In this gape, we obtain thorem I on volum of a n-dirmensional simplex and theorem 2 on dihedral angies of a simplex. Besides. We obtain Vasic inequality in E^n and its extension. The resultsin this paper contain and i...In this gape, we obtain thorem I on volum of a n-dirmensional simplex and theorem 2 on dihedral angies of a simplex. Besides. We obtain Vasic inequality in E^n and its extension. The resultsin this paper contain and improve the results in paper [1], [2], [3], [4].展开更多
Several experimental evidence suggests a link between brain Herpes simplex virus type-1 infection and the occurrence of Alzheimer’s disease.However,the molecular mechanisms underlying this association are not complet...Several experimental evidence suggests a link between brain Herpes simplex virus type-1 infection and the occurrence of Alzheimer’s disease.However,the molecular mechanisms underlying this association are not completely understood.Among the molecular mediators of synaptic and cognitive dysfunction occurring after Herpes simplex virus type-1 infection and reactivation in the brain neuroinflammatory cytokines seem to occupy a central role.Here,we specifically reviewed literature reports dealing with the impact of neuroinflammation on synaptic dysfunction observed after recurrent Herpes simplex virus type-1 reactivation in the brain,highlighting the role of interleukins and,in particular,interleukin 1βas a possible target against Herpes simplex virus type-1-induced neuronal dysfunctions.展开更多
BACKGROUND Aseptic meningitis is defined as meningeal inflammation caused by various etio-logies with negative cerebrospinal fluid(CSF)bacterial culture.The most common etiologies are viruses[enteroviruses,arboviruses...BACKGROUND Aseptic meningitis is defined as meningeal inflammation caused by various etio-logies with negative cerebrospinal fluid(CSF)bacterial culture.The most common etiologies are viruses[enteroviruses,arboviruses,and herpes simplex virus type 2(HSV-2)].Aseptic meningitis can have various presentations,including sensori-neural deafness.While sensorineural deafness from mumps meningoencephalitis has been reported,cases of HSV-2-induced hearing loss are rare.Herein,we re-port a case of HSV-2-induced meningitis that presented with sudden deafness.CASE SUMMARY A 68-year-old man experienced a profound sudden onset of left-sided hearing loss for one day.Pure-tone audiograms demonstrated sudden left-sided sensorineural hearing loss(thresholds 80-90 dB).After treatment with high-dose steroids for 1 week,he experienced an acute consciousness change with left hemiparesis.The laboratory data showed no significant abnormalities.Brain computed tomography without contrast and magnetic resonance imaging revealed no intracranial hemo-rrhage or obvious brain lesion.The CSF analysis and the Multiplex PCR panels showed HSV-2 positivity.Hence,under the diagnosis of herpes meningoenceph-alitis,acyclovir was prescribed and his symptoms gradually resolved.CONCLUSION This case report further demonstrates that a viral infection could be a cause of sudden sensorineural hearing loss.展开更多
Quercetin is a natural compound with potent antiviral effects;however,its role in the treatment of herpes simplex keratitis(HSK)remains underexplored.Here,we investigated the antiviral effects of quercetin against her...Quercetin is a natural compound with potent antiviral effects;however,its role in the treatment of herpes simplex keratitis(HSK)remains underexplored.Here,we investigated the antiviral effects of quercetin against herpes simplex virus 1(HSV-1).By examining different phases of viral infection in human corneal epithelial cells(HCECs),we found that 30μmol/L quercetin inhibits HSV-1 replication primarily by disrupting viral attachment.RNA-sequencing and subsequent analyses revealed that the nuclear factor E2-related factor 2(Nrf2)was upregulated by quercetin in a dose-dependent manner.Knocking down Nrf2 partially compromised quercetin's antiviral effect.Importantly,topical application of 100μmol/L quercetin alleviated HSK severity in mice,reduced viral titers in tears,and inhibited VP16 expression in the cornea and trigeminal ganglia.These findings demonstrate the antiviral effect of quercetin against HSV-1 and provide a foundation for mechanistic studies to elucidate its therapeutic potential in HSK.展开更多
The relation between the circum-radius and the in-radius of an n-dimensional simplex in E^n is studied.Two new generalizations of Euler inequality for the n-dimensional simplex are established.Besides,we obtain some s...The relation between the circum-radius and the in-radius of an n-dimensional simplex in E^n is studied.Two new generalizations of Euler inequality for the n-dimensional simplex are established.Besides,we obtain some stronger generalizations of Euler inequality for the n-dimensional simplex than previously known results.展开更多
In this paper, it is proved that the commutator Hβ,b which is generated by the n-dimensional fractional Hardy operator Hβ and b ∈λα （R^n） is bounded from L^p（R^n） to L^q（R^n）, where 0 〈 α 〈 1, 1 〈 p, q ...In this paper, it is proved that the commutator Hβ,b which is generated by the n-dimensional fractional Hardy operator Hβ and b ∈λα （R^n） is bounded from L^p（R^n） to L^q（R^n）, where 0 〈 α 〈 1, 1 〈 p, q 〈 ∞ and 1/P - 1/q = （α＋β）/n. Furthermore, the boundedness of Hβ,b on the homogenous Herz space Kq^α,p（R^n） is obtained.展开更多
Dynamic fault tree analysis is widely used for the reliability analysis of the complex system with dynamic failure characteristics. In many circumstances, the exact value of system reliability is difficult to obtain d...Dynamic fault tree analysis is widely used for the reliability analysis of the complex system with dynamic failure characteristics. In many circumstances, the exact value of system reliability is difficult to obtain due to absent or insufficient data for failure probabilities or failure rates of components. The traditional fuzzy operation arithmetic based on extension principle or interval theory may lead to fuzzy accumulations. Moreover, the existing fuzzy dynamic fault tree analysis methods are restricted to the case that all system components follow exponential time-to-failure distributions. To overcome these problems, a new fuzzy dynamic fault tree analysis approach based on the weakest n-dimensional t-norm arithmetic and developed sequential binary decision diagrams method is proposed to evaluate system fuzzy reliability. Compared with the existing approach,the proposed method can effectively reduce fuzzy cumulative and be applicable to any time-tofailure distribution type for system components. Finally, a case study is presented to illustrate the application and advantages of the proposed approach.展开更多
Here an asymptotic study to the N-dimensional radial Schrdinger equation for the quark-antiquark interaction potential employing asymptotic iteration method via an ansatz to the wavefunction is carried out. The comp...Here an asymptotic study to the N-dimensional radial Schrdinger equation for the quark-antiquark interaction potential employing asymptotic iteration method via an ansatz to the wavefunction is carried out. The complete energy spectra of the consigned system is obtained by computing and adding energy eigenvalues for ground state, for large " r" and for small " r". From this analysis, the mass spectra of heavy quarkonia is derived in three dimensions. Our analytical and numerical results are in good correspondence with other experimental and theoretical studies.展开更多
In this paper, the general calculation formulas of radial matrix elements for relativistic n-dimensional hydrogen atom of spin S=0 are obtained, and the recurrence relation of different power order radial matrix eleme...In this paper, the general calculation formulas of radial matrix elements for relativistic n-dimensional hydrogen atom of spin S=0 are obtained, and the recurrence relation of different power order radial matrix elements are also derived.展开更多
In this paper, inspired by the multiplicative generators of overlap functions, we mainly propose the concepts of multiplicative generator pairs of n-dimensional overlap functions, in order to extend the dimensionality...In this paper, inspired by the multiplicative generators of overlap functions, we mainly propose the concepts of multiplicative generator pairs of n-dimensional overlap functions, in order to extend the dimensionality of overlap functions from 2 to n. We present the condition under which the pair (g, h) can multiplicatively generate an n-dimensional overlap function O<sub>g,h</sub>. we focus on the homogeneity and idempotency property on multiplicatively generated n-dimensional overlap functions.展开更多
The aim of our minireview is to provide a brief overview of the diagnosis,clinical aspects,treatment options,management,and current literature available regarding herpes simplex keratitis(HSK).This type of corneal vir...The aim of our minireview is to provide a brief overview of the diagnosis,clinical aspects,treatment options,management,and current literature available regarding herpes simplex keratitis(HSK).This type of corneal viral infection is caused by the herpes simplex virus(HSV),which can affect several tissues,including the cornea.One significant aspect of HSK is its potential to cause recurrent episodes of inflammation and damage to the cornea.After the initial infection,the HSV can establish a latent infection in the trigeminal ganglion,a nerve cluster near the eye.The virus may remain dormant for extended periods.Periodic reactivation of the virus can occur,leading to recurrent episodes of HSK.Factors triggering reactivation include stress,illness,immunosuppression,or trauma.Recurrent episodes can manifest in different clinical patterns,ranging from mild epithelial involvement to more severe stromal or endothelial disease.The severity and frequency of recurrences vary among individuals.Severe cases of HSK,especially those involving the stroma and leading to scarring,can result in vision impairment or even blindness in extreme cases.The cornea's clarity is crucial for good vision,and scarring can compromise this,potentially leading to visual impairment.The management of HSK involves not only treating acute episodes but also implementing long-term strategies to prevent recurrences and attempt repairs of corneal nerve endings via neurotization.Antiviral medications,such as oral Acyclovir or topical Ganciclovir,may be prescribed for prophylaxis.The immune response to the virus can contribute to corneal damage.Inflammation,caused by the body's attempt to control the infection,may inadvertently harm the corneal tissues.Clinicians should be informed about triggers and advised on measures to minimize the risk of reactivation.In summary,the recurrent nature of HSK underscores the importance of both acute and long-term management strategies to preserve corneal health and maintain optimal visual function.展开更多
The solutions of the Laplace equation in n-dimensional space are studied. The angular eigenfunctions have the form of associated Jacob/polynomials. The radial solution of the Helmholtz equation is derived.
Acoustic emission(AE)source localization is a fundamental element of rock fracture damage imaging.To improve the efficiency and accuracy of AE source localization,this paper proposes a joint method comprising a three-...Acoustic emission(AE)source localization is a fundamental element of rock fracture damage imaging.To improve the efficiency and accuracy of AE source localization,this paper proposes a joint method comprising a three-dimensional(3D)AE source localization simplex method and grid search scanning.Using the concept of the geometry of simplexes,tetrahedral iterations were first conducted to narrow down the suspected source region.This is followed by a process of meshing the region and node searching to scan for optimal solutions,until the source location is determined.The resulting algorithm was tested using the artificial excitation source localization and uniaxial compression tests,after which the localization results were compared with the simplex and exhaustive methods.The results revealed that the localization obtained using the proposed method is more stable and can be effectively avoided compared with the simplex localization method.Furthermore,compared with the global scanning method,the proposed method is more efficient,with an average time of 10%–20%of the global scanning localization algorithm.Thus,the proposed algorithm is of great significance for laboratory research focused on locating rupture damages sustained by large-sized rock masses or test blocks.展开更多
It is proved that when solving SchrSdinger equations for radially symmetric potentials the effect of higher dimensions on the radial wave function is equivalent to the effect of higher angular momenta in lower-dimensi...It is proved that when solving SchrSdinger equations for radially symmetric potentials the effect of higher dimensions on the radial wave function is equivalent to the effect of higher angular momenta in lower-dimensional cases. This result is applied to giving solutions for several radially symmetric potentials in N dimensions.展开更多
Some new characterizations and immediate explicit expressions of best L(1≤p≤∞) approximation and their deviations by an n-dimensional subspace on a set of n+1 points are given.
In this paper, with the help of the eigenvalue properties of orthogonal tensors in n-dimensional Euclidean space and the representations of the orthogonal tensors in 2-dimensional space, the canonical representations ...In this paper, with the help of the eigenvalue properties of orthogonal tensors in n-dimensional Euclidean space and the representations of the orthogonal tensors in 2-dimensional space, the canonical representations of orthogonal tensors in n-dimensional Euclidean space are easily gotten. The paper also gives all the constraint relationships among the principal invariants of arbitrarily given orthogonal tensor by use of Cayley-Hamilton theorem; these results make it possible to solve all the eigenvalues of any orthogonal tensor based on a quite reduced equation of m-th order, where m is the integer part ofn \2. Finally, the formulae of the degree of freedom of orthogonal tensors are given.展开更多
Allicin, an antioxidant, is known for providing garlic with its unique fragrance and taste, as well as for its antimicrobial properties. Black garlic, a fermented form of garlic, contains higher levels of antioxidants...Allicin, an antioxidant, is known for providing garlic with its unique fragrance and taste, as well as for its antimicrobial properties. Black garlic, a fermented form of garlic, contains higher levels of antioxidants than fresh garlic. Antioxidants play a vital role in alleviating cellular stress during viral infections. Viral infections result in oxidative stress through the production of reactive oxidative species (ROS). A prolonged state of oxidative stress can result in cell death, DNA damage, and disease progression. In this study, black garlic extract (BGE) is evaluated for its ability to mitigate cytopathic effects and oxidative stress caused by herpes simplex virus-2 (HSV-2) infections in vitro. Antiviral assays were performed to determine the percent of viral inhibition resulting from treatment with the BGE. ROS-Glo<sup>TM</sup> H<sub>2</sub>O<sub>2</sub> assays were then completed to measure the post-infection ROS levels of BGE-treated virus and cells. The results thus far suggest that BGE may inhibit viral infection and decrease levels of oxidative stress.展开更多
AIM:To explore whether unilateral herpes simplex keratitis(HSK)can cause morphological changes of bilateral meibomian glands(MGs)based on artificial intelligence(AI)analytical system.METHODS:In the retrospective study...AIM:To explore whether unilateral herpes simplex keratitis(HSK)can cause morphological changes of bilateral meibomian glands(MGs)based on artificial intelligence(AI)analytical system.METHODS:In the retrospective study,29 patients with unilateral HSK and 29 participants matched in terms of age and sex were included as control group.Meibographic images of the upper eyelid using Keratograph 5M and assessed ocular surface parameters including tear meniscus height and tear break-up time.MG density and vagueness values were automatically analyzed and calculated using an AI analytical system.We compared the differences between the affected and the contralateral unaffected eyes in HSK patients,and the normal control eyes.We employed either the paired t-test or the Wilcoxon signed-rank test to compare significant difference between the affected and unaffected eyes in HSK patients or between the HSK group and control group.RESULTS:The MG density was 0.19±0.09 in the HSKaffected eye and 0.18±0.07 in contralateral unaffected eye,which had no significant difference(P=0.616).The MG density between the affected eye with HSK and the normal control group was statistically significant(P=0.028).There was a significant difference in MG density between the contralateral unaffected eye and the normal control group(P=0.012).However,no significant difference in vagueness value was observed between the eye with HSK and the control group or between HSK eye and contralateral eye.CONCLUSION:The MG density between the HSKaffected eye and the contralateral unaffected eye don’t significantly differ,whereas there is a significant decrease in the HSK group compared to that of the normal participants.Unilateral HSV keratitis may suffer from bilateral changes of MG morphology indicating bilateral dry eye.Therefore,the fellow eye of patients with unilateral HSK should be considered a potential case of MG dysfunction,necessitating early treatment for bilateral dry eye in the clinic.展开更多
This paper proposes an improved version of the Partial Reinforcement Optimizer(PRO),termed LNPRO.The LNPRO has undergone a learner phase,which allows for further communication of information among the PRO population,c...This paper proposes an improved version of the Partial Reinforcement Optimizer(PRO),termed LNPRO.The LNPRO has undergone a learner phase,which allows for further communication of information among the PRO population,changing the state of the PRO in terms of self-strengthening.Furthermore,the Nelder-Mead simplex is used to optimize the best agent in the population,accelerating the convergence speed and improving the accuracy of the PRO population.By comparing LNPRO with nine advanced algorithms in the IEEE CEC 2022 benchmark function,the convergence accuracy of the LNPRO has been verified.The accuracy and stability of simulated data and real data in the parameter extraction of PV systems are crucial.Compared to the PRO,the precision and stability of LNPRO have indeed been enhanced in four types of photovoltaic components,and it is also superior to other excellent algorithms.To further verify the parameter extraction problem of LNPRO in complex environments,LNPRO has been applied to three types of manufacturer data,demonstrating excellent results under varying irradiation and temperatures.In summary,LNPRO holds immense potential in solving the parameter extraction problems in PV systems.展开更多
文摘In this gape, we obtain thorem I on volum of a n-dirmensional simplex and theorem 2 on dihedral angies of a simplex. Besides. We obtain Vasic inequality in E^n and its extension. The resultsin this paper contain and improve the results in paper [1], [2], [3], [4].
基金supported by UniversitàCattolica(D1 intramural funds to RP)Italian Ministry of University and Research(PRIN 2022ZYLB7B,P2022YW7BP funds to CG).
文摘Several experimental evidence suggests a link between brain Herpes simplex virus type-1 infection and the occurrence of Alzheimer’s disease.However,the molecular mechanisms underlying this association are not completely understood.Among the molecular mediators of synaptic and cognitive dysfunction occurring after Herpes simplex virus type-1 infection and reactivation in the brain neuroinflammatory cytokines seem to occupy a central role.Here,we specifically reviewed literature reports dealing with the impact of neuroinflammation on synaptic dysfunction observed after recurrent Herpes simplex virus type-1 reactivation in the brain,highlighting the role of interleukins and,in particular,interleukin 1βas a possible target against Herpes simplex virus type-1-induced neuronal dysfunctions.
文摘BACKGROUND Aseptic meningitis is defined as meningeal inflammation caused by various etio-logies with negative cerebrospinal fluid(CSF)bacterial culture.The most common etiologies are viruses[enteroviruses,arboviruses,and herpes simplex virus type 2(HSV-2)].Aseptic meningitis can have various presentations,including sensori-neural deafness.While sensorineural deafness from mumps meningoencephalitis has been reported,cases of HSV-2-induced hearing loss are rare.Herein,we re-port a case of HSV-2-induced meningitis that presented with sudden deafness.CASE SUMMARY A 68-year-old man experienced a profound sudden onset of left-sided hearing loss for one day.Pure-tone audiograms demonstrated sudden left-sided sensorineural hearing loss(thresholds 80-90 dB).After treatment with high-dose steroids for 1 week,he experienced an acute consciousness change with left hemiparesis.The laboratory data showed no significant abnormalities.Brain computed tomography without contrast and magnetic resonance imaging revealed no intracranial hemo-rrhage or obvious brain lesion.The CSF analysis and the Multiplex PCR panels showed HSV-2 positivity.Hence,under the diagnosis of herpes meningoenceph-alitis,acyclovir was prescribed and his symptoms gradually resolved.CONCLUSION This case report further demonstrates that a viral infection could be a cause of sudden sensorineural hearing loss.
基金supported by the National Natural Science Foundation of China(No.81970848).
文摘Quercetin is a natural compound with potent antiviral effects;however,its role in the treatment of herpes simplex keratitis(HSK)remains underexplored.Here,we investigated the antiviral effects of quercetin against herpes simplex virus 1(HSV-1).By examining different phases of viral infection in human corneal epithelial cells(HCECs),we found that 30μmol/L quercetin inhibits HSV-1 replication primarily by disrupting viral attachment.RNA-sequencing and subsequent analyses revealed that the nuclear factor E2-related factor 2(Nrf2)was upregulated by quercetin in a dose-dependent manner.Knocking down Nrf2 partially compromised quercetin's antiviral effect.Importantly,topical application of 100μmol/L quercetin alleviated HSK severity in mice,reduced viral titers in tears,and inhibited VP16 expression in the cornea and trigeminal ganglia.These findings demonstrate the antiviral effect of quercetin against HSV-1 and provide a foundation for mechanistic studies to elucidate its therapeutic potential in HSK.
基金Foundation item： Supported by the National Science Foundation of China（60671051） Supported by the Foundation of Anhui Higher School（KJ2009A45）
文摘The relation between the circum-radius and the in-radius of an n-dimensional simplex in E^n is studied.Two new generalizations of Euler inequality for the n-dimensional simplex are established.Besides,we obtain some stronger generalizations of Euler inequality for the n-dimensional simplex than previously known results.
基金The NSF (Q2008A01) of Shandong,Chinathe NSF (10871024) of China
文摘In this paper, it is proved that the commutator Hβ,b which is generated by the n-dimensional fractional Hardy operator Hβ and b ∈λα （R^n） is bounded from L^p（R^n） to L^q（R^n）, where 0 〈 α 〈 1, 1 〈 p, q 〈 ∞ and 1/P - 1/q = （α＋β）/n. Furthermore, the boundedness of Hβ,b on the homogenous Herz space Kq^α,p（R^n） is obtained.
基金supported by the National Defense Basic Scientific Research program of China (No.61325102)
文摘Dynamic fault tree analysis is widely used for the reliability analysis of the complex system with dynamic failure characteristics. In many circumstances, the exact value of system reliability is difficult to obtain due to absent or insufficient data for failure probabilities or failure rates of components. The traditional fuzzy operation arithmetic based on extension principle or interval theory may lead to fuzzy accumulations. Moreover, the existing fuzzy dynamic fault tree analysis methods are restricted to the case that all system components follow exponential time-to-failure distributions. To overcome these problems, a new fuzzy dynamic fault tree analysis approach based on the weakest n-dimensional t-norm arithmetic and developed sequential binary decision diagrams method is proposed to evaluate system fuzzy reliability. Compared with the existing approach,the proposed method can effectively reduce fuzzy cumulative and be applicable to any time-tofailure distribution type for system components. Finally, a case study is presented to illustrate the application and advantages of the proposed approach.
基金University Grant Commission(UGC) INDIA for providing the financial assistance in terms of UGC-SRF
文摘Here an asymptotic study to the N-dimensional radial Schrdinger equation for the quark-antiquark interaction potential employing asymptotic iteration method via an ansatz to the wavefunction is carried out. The complete energy spectra of the consigned system is obtained by computing and adding energy eigenvalues for ground state, for large " r" and for small " r". From this analysis, the mass spectra of heavy quarkonia is derived in three dimensions. Our analytical and numerical results are in good correspondence with other experimental and theoretical studies.
文摘In this paper, the general calculation formulas of radial matrix elements for relativistic n-dimensional hydrogen atom of spin S=0 are obtained, and the recurrence relation of different power order radial matrix elements are also derived.
文摘In this paper, inspired by the multiplicative generators of overlap functions, we mainly propose the concepts of multiplicative generator pairs of n-dimensional overlap functions, in order to extend the dimensionality of overlap functions from 2 to n. We present the condition under which the pair (g, h) can multiplicatively generate an n-dimensional overlap function O<sub>g,h</sub>. we focus on the homogeneity and idempotency property on multiplicatively generated n-dimensional overlap functions.
文摘The aim of our minireview is to provide a brief overview of the diagnosis,clinical aspects,treatment options,management,and current literature available regarding herpes simplex keratitis(HSK).This type of corneal viral infection is caused by the herpes simplex virus(HSV),which can affect several tissues,including the cornea.One significant aspect of HSK is its potential to cause recurrent episodes of inflammation and damage to the cornea.After the initial infection,the HSV can establish a latent infection in the trigeminal ganglion,a nerve cluster near the eye.The virus may remain dormant for extended periods.Periodic reactivation of the virus can occur,leading to recurrent episodes of HSK.Factors triggering reactivation include stress,illness,immunosuppression,or trauma.Recurrent episodes can manifest in different clinical patterns,ranging from mild epithelial involvement to more severe stromal or endothelial disease.The severity and frequency of recurrences vary among individuals.Severe cases of HSK,especially those involving the stroma and leading to scarring,can result in vision impairment or even blindness in extreme cases.The cornea's clarity is crucial for good vision,and scarring can compromise this,potentially leading to visual impairment.The management of HSK involves not only treating acute episodes but also implementing long-term strategies to prevent recurrences and attempt repairs of corneal nerve endings via neurotization.Antiviral medications,such as oral Acyclovir or topical Ganciclovir,may be prescribed for prophylaxis.The immune response to the virus can contribute to corneal damage.Inflammation,caused by the body's attempt to control the infection,may inadvertently harm the corneal tissues.Clinicians should be informed about triggers and advised on measures to minimize the risk of reactivation.In summary,the recurrent nature of HSK underscores the importance of both acute and long-term management strategies to preserve corneal health and maintain optimal visual function.
基金Supported by the Nationa1 Natural Science Foundation of China under Grant No.10874018"the Fundamental Research Funds for the Central Universities"
文摘The solutions of the Laplace equation in n-dimensional space are studied. The angular eigenfunctions have the form of associated Jacob/polynomials. The radial solution of the Helmholtz equation is derived.
基金supported by the Natural Science Foundation of Henan Province(No.222300420596)China Railway Science and Technology Innovation Program Funded Project(CZ02-Special-03)Science and Technology Innovation Project funded by China Railway Tunnel Group(Tunnel Research 2021-03)。
文摘Acoustic emission(AE)source localization is a fundamental element of rock fracture damage imaging.To improve the efficiency and accuracy of AE source localization,this paper proposes a joint method comprising a three-dimensional(3D)AE source localization simplex method and grid search scanning.Using the concept of the geometry of simplexes,tetrahedral iterations were first conducted to narrow down the suspected source region.This is followed by a process of meshing the region and node searching to scan for optimal solutions,until the source location is determined.The resulting algorithm was tested using the artificial excitation source localization and uniaxial compression tests,after which the localization results were compared with the simplex and exhaustive methods.The results revealed that the localization obtained using the proposed method is more stable and can be effectively avoided compared with the simplex localization method.Furthermore,compared with the global scanning method,the proposed method is more efficient,with an average time of 10%–20%of the global scanning localization algorithm.Thus,the proposed algorithm is of great significance for laboratory research focused on locating rupture damages sustained by large-sized rock masses or test blocks.
基金The project partly supported by National Natural Science Foundation of China under Grant No. 10247001.The author would like to thank Prof. T.D. Lee for his continuous guidance and instruction.
文摘It is proved that when solving SchrSdinger equations for radially symmetric potentials the effect of higher dimensions on the radial wave function is equivalent to the effect of higher angular momenta in lower-dimensional cases. This result is applied to giving solutions for several radially symmetric potentials in N dimensions.
文摘Some new characterizations and immediate explicit expressions of best L(1≤p≤∞) approximation and their deviations by an n-dimensional subspace on a set of n+1 points are given.
文摘In this paper, with the help of the eigenvalue properties of orthogonal tensors in n-dimensional Euclidean space and the representations of the orthogonal tensors in 2-dimensional space, the canonical representations of orthogonal tensors in n-dimensional Euclidean space are easily gotten. The paper also gives all the constraint relationships among the principal invariants of arbitrarily given orthogonal tensor by use of Cayley-Hamilton theorem; these results make it possible to solve all the eigenvalues of any orthogonal tensor based on a quite reduced equation of m-th order, where m is the integer part ofn \2. Finally, the formulae of the degree of freedom of orthogonal tensors are given.
文摘Allicin, an antioxidant, is known for providing garlic with its unique fragrance and taste, as well as for its antimicrobial properties. Black garlic, a fermented form of garlic, contains higher levels of antioxidants than fresh garlic. Antioxidants play a vital role in alleviating cellular stress during viral infections. Viral infections result in oxidative stress through the production of reactive oxidative species (ROS). A prolonged state of oxidative stress can result in cell death, DNA damage, and disease progression. In this study, black garlic extract (BGE) is evaluated for its ability to mitigate cytopathic effects and oxidative stress caused by herpes simplex virus-2 (HSV-2) infections in vitro. Antiviral assays were performed to determine the percent of viral inhibition resulting from treatment with the BGE. ROS-Glo<sup>TM</sup> H<sub>2</sub>O<sub>2</sub> assays were then completed to measure the post-infection ROS levels of BGE-treated virus and cells. The results thus far suggest that BGE may inhibit viral infection and decrease levels of oxidative stress.
基金Supported by Zhejiang Provincial Medical and Health Science Technology Program,Health Commission of Zhejiang Province(No.2022PY074)Science and Technology Program of Wenzhou City(No.Y2020335).
文摘AIM:To explore whether unilateral herpes simplex keratitis(HSK)can cause morphological changes of bilateral meibomian glands(MGs)based on artificial intelligence(AI)analytical system.METHODS:In the retrospective study,29 patients with unilateral HSK and 29 participants matched in terms of age and sex were included as control group.Meibographic images of the upper eyelid using Keratograph 5M and assessed ocular surface parameters including tear meniscus height and tear break-up time.MG density and vagueness values were automatically analyzed and calculated using an AI analytical system.We compared the differences between the affected and the contralateral unaffected eyes in HSK patients,and the normal control eyes.We employed either the paired t-test or the Wilcoxon signed-rank test to compare significant difference between the affected and unaffected eyes in HSK patients or between the HSK group and control group.RESULTS:The MG density was 0.19±0.09 in the HSKaffected eye and 0.18±0.07 in contralateral unaffected eye,which had no significant difference(P=0.616).The MG density between the affected eye with HSK and the normal control group was statistically significant(P=0.028).There was a significant difference in MG density between the contralateral unaffected eye and the normal control group(P=0.012).However,no significant difference in vagueness value was observed between the eye with HSK and the control group or between HSK eye and contralateral eye.CONCLUSION:The MG density between the HSKaffected eye and the contralateral unaffected eye don’t significantly differ,whereas there is a significant decrease in the HSK group compared to that of the normal participants.Unilateral HSV keratitis may suffer from bilateral changes of MG morphology indicating bilateral dry eye.Therefore,the fellow eye of patients with unilateral HSK should be considered a potential case of MG dysfunction,necessitating early treatment for bilateral dry eye in the clinic.
基金supported in part by the Natural Science Foundation of Zhejiang Province(LTGS23E070001).
文摘This paper proposes an improved version of the Partial Reinforcement Optimizer(PRO),termed LNPRO.The LNPRO has undergone a learner phase,which allows for further communication of information among the PRO population,changing the state of the PRO in terms of self-strengthening.Furthermore,the Nelder-Mead simplex is used to optimize the best agent in the population,accelerating the convergence speed and improving the accuracy of the PRO population.By comparing LNPRO with nine advanced algorithms in the IEEE CEC 2022 benchmark function,the convergence accuracy of the LNPRO has been verified.The accuracy and stability of simulated data and real data in the parameter extraction of PV systems are crucial.Compared to the PRO,the precision and stability of LNPRO have indeed been enhanced in four types of photovoltaic components,and it is also superior to other excellent algorithms.To further verify the parameter extraction problem of LNPRO in complex environments,LNPRO has been applied to three types of manufacturer data,demonstrating excellent results under varying irradiation and temperatures.In summary,LNPRO holds immense potential in solving the parameter extraction problems in PV systems.
