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Expanding the Scope of Multivariate Regression Approaches in Cross-Omics Research
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作者 Xiaoxi Hu Yue Ma +2 位作者 Yakun Xu Peiyao Zhao Jun Wang 《Engineering》 SCIE EI 2021年第12期1725-1731,共7页
Recent technological advancements and developments have led to a dramatic increase in the amount of high-dimensional data and thus have increased the demand for proper and efficient multivariate regression methods.Num... Recent technological advancements and developments have led to a dramatic increase in the amount of high-dimensional data and thus have increased the demand for proper and efficient multivariate regression methods.Numerous traditional multivariate approaches such as principal component analysis have been used broadly in various research areas,including investment analysis,image identification,and population genetic structure analysis.However,these common approaches have the limitations of ignoring the correlations between responses and a low variable selection efficiency.Therefore,in this article,we introduce the reduced rank regression method and its extensions,sparse reduced rank regression and subspace assisted regression with row sparsity,which hold potential to meet the above demands and thus improve the interpretability of regression models.We conducted a simulation study to evaluate their performance and compared them with several other variable selection methods.For different application scenarios,we also provide selection suggestions based on predictive ability and variable selection accuracy.Finally,to demonstrate the practical value of these methods in the field of microbiome research,we applied our chosen method to real population-level microbiome data,the results of which validated our method.Our method extensions provide valuable guidelines for future omics research,especially with respect to multivariate regression,and could pave the way for novel discoveries in microbiome and related research fields. 展开更多
关键词 multivariate regression methods Reduced rank regression SPARSITY Dimensionality reduction Variable selection
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Prediction of lateral wall deflections of excavations in water-rich sands by a modified multivariate-adaptiveregression- splines method
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作者 Dongdong FAN Delujia GONG +1 位作者 Yong TAN Yongjing TANG 《Frontiers of Structural and Civil Engineering》 CSCD 2024年第12期1971-1984,共14页
Machine learning methods have advantages in predicting excavation-induced lateral wall displacements.Due to lack of sufficient field data,training data for prediction models were often derived from the results of nume... Machine learning methods have advantages in predicting excavation-induced lateral wall displacements.Due to lack of sufficient field data,training data for prediction models were often derived from the results of numerical simulations,leading to poor prediction accuracy.Based on a specific quantity of data,a multivariate adaptive regression splines method(MARS)was introduced to predict lateral wall deflections caused by deep excavations in thick water-rich sands.Sensitivity of lateral wall deflections to affecting factors was analyzed.It is disclosed that dewatering mode has the most significant influence on lateral wall deflections,while the soil cohesion has the least influence.Using crossvalidation analysis,weights were introduced to modify the MARS method to optimize the prediction model.Comparison of the predicted and measured deflections shows that the prediction based on the modified multivariate adaptive regression splines method(MMARS)is more accurate than that based on the traditional MARS method.The prediction model established in this paper can help engineers make predictions for wall displacement,and the proposed methodology can also serve as a reference for researchers to develop prediction models. 展开更多
关键词 lateral wall deflection machine learning multivariate adaptive regression splines method excavation database water-rich sand
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