Polyacrylonitrile-based commercial carbon fibers(CFs)have garnered significant attention in mechanical applications because of their exceptional mechanical properties.However,their functional versatility relies heavil...Polyacrylonitrile-based commercial carbon fibers(CFs)have garnered significant attention in mechanical applications because of their exceptional mechanical properties.However,their functional versatility relies heavily on the structural intricacies of duplex carbon layers.Current modification approaches,though effective,are encumbered by complexity and cost,limiting widespread adoption across diverse fields.We herein present a straightforward modification strategy centered on regulating carbon layers to unlock the multifunctional potential of CFs.Our method leverages two common anions,Cl^(-)and SO_(4)^(2-),to facilitate oxidation reactions in CFs under robust alkali and high voltage conditions.Cl^(-)effectively activates carbon layers,while SO_(4)^(2-)facilitates layer movement.The electrocatalytic activities of the resultant CFs are enhanced,with state-of-the-art performance as supercapacitors and exceptional stability.Moreover,our approach achieves a groundbreaking milestone by bending and fusing CFs without using binders.This breakthrough can reduce the manufacturing costs of CF-based products.It also facilitates the development of novel microelectronic devices.展开更多
Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine.Citrate-based polymers are the few bioactive polymer biomaterials used in biomedic...Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine.Citrate-based polymers are the few bioactive polymer biomaterials used in biomedicine because of their facile synthesis,controllable structure,biocompatibility,biomimetic viscoelastic mechanical behavior,and functional groups available for modification.In recent years,various multifunctional designs and biomedical applications,including cardiovascular,orthopedic,muscle tissue,skin tissue,nerve and spinal cord,bioimaging,and drug or gene delivery based on citrate-based polymers,have been extensively studied,and many of them have good clinical application potential.In this review,we summarize recent progress in the multifunctional design and biomedical applications of citrate-based polymers.We also discuss the further development of multifunctional citrate-based polymers with tailored properties to meet the requirements of various biomedical applications.展开更多
Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural plants.In this paper,a novel method of dyeing and multifunctional modification of silk fabric by impregnation with rib...Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural plants.In this paper,a novel method of dyeing and multifunctional modification of silk fabric by impregnation with riboflavin sodium phosphate was proposed,such that protein silk fabric can be endowed with bright yellow color and multi-functionality.The results of this paper confirmed that the pH and concentration of riboflavin sodium phosphate solution are critical factors for dyeing and multifunctional modification.Attractively,the photochromic performance was one of the most distinctive features of the modified silk fabric,and the dyed silk fabric turned into fluorescent green from original yellow under 365 nm ultraviolet lamp.Furthermore,the modified silk fabric exhibited good antibacterial properties with a high inhibition rate of 92%for Escherichia coli.Besides,the flame retardancy of silk fabric was significantly improved after modification.The damaged length of modified silk fabric with 40%owf riboflavin sodium phosphate was lower than 10.4 cm and passed the B1 classification.As revealed by the result of this paper,riboflavin sodium phosphate is sufficiently effective in serving as an eco-friendly multifunctional agent for strengthening the add-value of silk textiles.展开更多
Ultrasmall silica nanoparticles,as one type of nanocarriers featured by excellent biocompatibility and efficient renal clearance,are of rapidly growing interest for biomedical applications,particularly in oncology.Und...Ultrasmall silica nanoparticles,as one type of nanocarriers featured by excellent biocompatibility and efficient renal clearance,are of rapidly growing interest for biomedical applications,particularly in oncology.Undesirably,the intrinsic issues of low site-targeting capability,short circulation time,and limited functionalities of ultrasmall silica nanoparticles severely impede their widespread application in the biomedical domain.Recent researches on surface modification for improved physical properties,enhanced site-specific abilities and multimodality imaging have been continuously emerging,which provide the prerequisite for possible application in the integration of diagnosis and treatment.On this basis,this review summarizes the most widely used synthesis approaches for wellordered ultrasmall silica nanoparticles with uniform diameter and tunable pore size,and simultaneously highlights the diverse surface functionalization for versatile purposes and biomedical applications,including site-targeted delivery of drugs,stimuli-responsive cargo release,real-time bioimaging as well as cancer theranostics.Finally,the challenges of ultrasmall silica nanoparticles in oncology are further discussed with the aim of promoting their future clinical application.展开更多
基金support from the Key-Area Research and Development Program of Guangdong Province(2019B111107002)the National Natural Science Foundation of China(52478266 and 52108231)+1 种基金the Basic and Applied Basic Research Fund of Guangdong Province(2023A1515012150 and 2023A1515012409)the Shenzhen Science and Technology Innovation Program(20220810140230001 and 20220810160453001).
文摘Polyacrylonitrile-based commercial carbon fibers(CFs)have garnered significant attention in mechanical applications because of their exceptional mechanical properties.However,their functional versatility relies heavily on the structural intricacies of duplex carbon layers.Current modification approaches,though effective,are encumbered by complexity and cost,limiting widespread adoption across diverse fields.We herein present a straightforward modification strategy centered on regulating carbon layers to unlock the multifunctional potential of CFs.Our method leverages two common anions,Cl^(-)and SO_(4)^(2-),to facilitate oxidation reactions in CFs under robust alkali and high voltage conditions.Cl^(-)effectively activates carbon layers,while SO_(4)^(2-)facilitates layer movement.The electrocatalytic activities of the resultant CFs are enhanced,with state-of-the-art performance as supercapacitors and exceptional stability.Moreover,our approach achieves a groundbreaking milestone by bending and fusing CFs without using binders.This breakthrough can reduce the manufacturing costs of CF-based products.It also facilitates the development of novel microelectronic devices.
基金supported by the National Natural Science Foundation of China(grant No.52172288)Special Support Program for High Level Talents of Shaanxi Province of China(grant No.TZ0278)+4 种基金the key R&D plan of Shaanxi Province of China(grant No.2021GXLH-Z-052)State Key Laboratory for Manufacturing Systems Engineering of China(grant No.sklms2021006)Young Talent Support Plan of Xi’an Jiaotong University of China(grant No.QY6J003)the Fundamental Research Funds for the Central Universities(grant No.xzy012021075)China Postdoctoral Science Foundation(grant No.2021M702644).
文摘Developing bioactive biomaterials with highly controlled functions is crucial to enhancing their applications in regenerative medicine.Citrate-based polymers are the few bioactive polymer biomaterials used in biomedicine because of their facile synthesis,controllable structure,biocompatibility,biomimetic viscoelastic mechanical behavior,and functional groups available for modification.In recent years,various multifunctional designs and biomedical applications,including cardiovascular,orthopedic,muscle tissue,skin tissue,nerve and spinal cord,bioimaging,and drug or gene delivery based on citrate-based polymers,have been extensively studied,and many of them have good clinical application potential.In this review,we summarize recent progress in the multifunctional design and biomedical applications of citrate-based polymers.We also discuss the further development of multifunctional citrate-based polymers with tailored properties to meet the requirements of various biomedical applications.
基金The present work was found by Natural Science Foundation of Jiangsu Province(Grant No.BK20200868)Natural Science Fund for Universities and Colleges in Jiangsu Province(Grant No.20KJB540002).
文摘Riboflavin sodium phosphate has been confirmed as a promising biomass product derived from natural plants.In this paper,a novel method of dyeing and multifunctional modification of silk fabric by impregnation with riboflavin sodium phosphate was proposed,such that protein silk fabric can be endowed with bright yellow color and multi-functionality.The results of this paper confirmed that the pH and concentration of riboflavin sodium phosphate solution are critical factors for dyeing and multifunctional modification.Attractively,the photochromic performance was one of the most distinctive features of the modified silk fabric,and the dyed silk fabric turned into fluorescent green from original yellow under 365 nm ultraviolet lamp.Furthermore,the modified silk fabric exhibited good antibacterial properties with a high inhibition rate of 92%for Escherichia coli.Besides,the flame retardancy of silk fabric was significantly improved after modification.The damaged length of modified silk fabric with 40%owf riboflavin sodium phosphate was lower than 10.4 cm and passed the B1 classification.As revealed by the result of this paper,riboflavin sodium phosphate is sufficiently effective in serving as an eco-friendly multifunctional agent for strengthening the add-value of silk textiles.
基金financially supported by the National Natural Science Foundation of China(92059202,82330060,82302273)the Funding of Double First-Rate Discipline Innovation Team of China Pharmaceutical University(CPUQNJC22_04)the Fundamental Research Funds for the Central Universities of China(2632023TD01).
文摘Ultrasmall silica nanoparticles,as one type of nanocarriers featured by excellent biocompatibility and efficient renal clearance,are of rapidly growing interest for biomedical applications,particularly in oncology.Undesirably,the intrinsic issues of low site-targeting capability,short circulation time,and limited functionalities of ultrasmall silica nanoparticles severely impede their widespread application in the biomedical domain.Recent researches on surface modification for improved physical properties,enhanced site-specific abilities and multimodality imaging have been continuously emerging,which provide the prerequisite for possible application in the integration of diagnosis and treatment.On this basis,this review summarizes the most widely used synthesis approaches for wellordered ultrasmall silica nanoparticles with uniform diameter and tunable pore size,and simultaneously highlights the diverse surface functionalization for versatile purposes and biomedical applications,including site-targeted delivery of drugs,stimuli-responsive cargo release,real-time bioimaging as well as cancer theranostics.Finally,the challenges of ultrasmall silica nanoparticles in oncology are further discussed with the aim of promoting their future clinical application.
