Integration can diversify the function of a device with the same volume, therefore it facilitates the development of portable, wearable and flexible electronics. In this review, we described several kinds of novel and...Integration can diversify the function of a device with the same volume, therefore it facilitates the development of portable, wearable and flexible electronics. In this review, we described several kinds of novel and unconventional multifunctional integrated supercapacitors which can not only be used to storage energy but also be applied to other fields such as photodetecting, electrochromics, monitoring physiological/mechanical activities, gas sensor, and so on. First, a brief introduction of the significance and advantages of multifunctional integrated supercapacitors was presented. Then we outlined the enormous progress which has been made in the area of multifunctional integrated supercapacitors. In the end, the prospects and further developments in this exciting field were also suggested.展开更多
Thermotherapy is a conventional and effective physiotherapy for arthritis.However,the current thermotherapy devices are often bulky and lack real-time temperature feedback and self-adjustment functions.Here,we develop...Thermotherapy is a conventional and effective physiotherapy for arthritis.However,the current thermotherapy devices are often bulky and lack real-time temperature feedback and self-adjustment functions.Here,we developed a multifunctional wearable system for real-time thermotherapy of arthritic joints based on a multilayered flexible electronic device consisting of homomorphic hollow thin-film sensors and heater.The kirigami−serpentine thin-film sensors provide stretchability and rapid response to changes in environmental temperature and humidity,and the homomorphic design offers easy de-coupling of dual-modal sensing signals.Based on a closed-loop control,the thin-film Joule heater exhibits rapid and stable temperature regulation capability,with thermal response time<1's and maximum deviation<0.4℃ at 45℃.Based on the multifunctional wearable system,we developed a series of user-friendly gears and demonstrated programmable on-demand thermotherapy,real-time personal thermal management,thermal dehumidification,and relief of the pain via increasing blood perfusion.Our innovation offers a promising solution for arthritis management and has the potential to benefit the well-being of thousands of patients.展开更多
Organoids have gained significant interest due to their ability to recapitulate the structural,molecular,and functional complexity of corresponding organs.While methods have been developed to characterize and benchmar...Organoids have gained significant interest due to their ability to recapitulate the structural,molecular,and functional complexity of corresponding organs.While methods have been developed to characterize and benchmark organoid structural and molecular properties,capturing the functional development and maturation of organoids remains challenging.To address this,the development of multifunctional bioelectronics for interfacing with organoids has been actively pursued.However,conventional electronics face limitations in achieving multifunctional recording and control across the entire three-dimensional(3D)volume of organoids in a long-term stable manner due to the large morphological and cellular composition changes during development.In this review,we first discuss the application of conventional electronics for organoid interfacing.We then focus on the development of flexible and stretchable electronics designed to create organoid/electronics hybrids for chronically stable interfaces.We also review recent advancements in flexible multifunctional electronics for charting multimodal cell activities throughout development.Furthermore,we explore the integration of flexible bioelectronics with other characterization modalities for comprehensive multimodal charting of cells within 3D tissues.Finally,we discuss the potential of integrating artificial intelligence into the organoid system through embedded electronics,harnessing organoid intelligence for biosymbiotic computational systems.These advancements could provide valuable tools for characterizing organoid functional development and maturation,establishing patient-specific models,developing therapeutic opportunities,and exploring novel computational strategies.展开更多
基金financial support of the National Natural Science Foundation of China(No.51502009)the Key Laboratory of Jiangxi Province for Persistent Pollutants Control and Resources Recycle(No.ST201522008)
文摘Integration can diversify the function of a device with the same volume, therefore it facilitates the development of portable, wearable and flexible electronics. In this review, we described several kinds of novel and unconventional multifunctional integrated supercapacitors which can not only be used to storage energy but also be applied to other fields such as photodetecting, electrochromics, monitoring physiological/mechanical activities, gas sensor, and so on. First, a brief introduction of the significance and advantages of multifunctional integrated supercapacitors was presented. Then we outlined the enormous progress which has been made in the area of multifunctional integrated supercapacitors. In the end, the prospects and further developments in this exciting field were also suggested.
基金supported by the National Natural Science Foundation of China(U23A20362,51875083)the funding from Dalian University of Technology(DUT23YG215,DUT22LAB504).
文摘Thermotherapy is a conventional and effective physiotherapy for arthritis.However,the current thermotherapy devices are often bulky and lack real-time temperature feedback and self-adjustment functions.Here,we developed a multifunctional wearable system for real-time thermotherapy of arthritic joints based on a multilayered flexible electronic device consisting of homomorphic hollow thin-film sensors and heater.The kirigami−serpentine thin-film sensors provide stretchability and rapid response to changes in environmental temperature and humidity,and the homomorphic design offers easy de-coupling of dual-modal sensing signals.Based on a closed-loop control,the thin-film Joule heater exhibits rapid and stable temperature regulation capability,with thermal response time<1's and maximum deviation<0.4℃ at 45℃.Based on the multifunctional wearable system,we developed a series of user-friendly gears and demonstrated programmable on-demand thermotherapy,real-time personal thermal management,thermal dehumidification,and relief of the pain via increasing blood perfusion.Our innovation offers a promising solution for arthritis management and has the potential to benefit the well-being of thousands of patients.
基金supported by grants from NIH/NIMH 1RF1MH123948NIH/NIDDK 1DP1DK130673+2 种基金NIH/NSF ECCS-2038603NIH/NLM 5R01LM014465the support of the Kwanjeong Educational Foundation.
文摘Organoids have gained significant interest due to their ability to recapitulate the structural,molecular,and functional complexity of corresponding organs.While methods have been developed to characterize and benchmark organoid structural and molecular properties,capturing the functional development and maturation of organoids remains challenging.To address this,the development of multifunctional bioelectronics for interfacing with organoids has been actively pursued.However,conventional electronics face limitations in achieving multifunctional recording and control across the entire three-dimensional(3D)volume of organoids in a long-term stable manner due to the large morphological and cellular composition changes during development.In this review,we first discuss the application of conventional electronics for organoid interfacing.We then focus on the development of flexible and stretchable electronics designed to create organoid/electronics hybrids for chronically stable interfaces.We also review recent advancements in flexible multifunctional electronics for charting multimodal cell activities throughout development.Furthermore,we explore the integration of flexible bioelectronics with other characterization modalities for comprehensive multimodal charting of cells within 3D tissues.Finally,we discuss the potential of integrating artificial intelligence into the organoid system through embedded electronics,harnessing organoid intelligence for biosymbiotic computational systems.These advancements could provide valuable tools for characterizing organoid functional development and maturation,establishing patient-specific models,developing therapeutic opportunities,and exploring novel computational strategies.
