BACKGROUND Post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis is a common complication of the procedure.The effective prevention of post-ERCP pancreatitis(PEP)remains a key focus of clinical researc...BACKGROUND Post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis is a common complication of the procedure.The effective prevention of post-ERCP pancreatitis(PEP)remains a key focus of clinical research.AIM To develop a prediction model for PEP based on multidimensional clinical indicators and evaluate its clinical application value.METHODS We retrospectively analyzed 183 patients with biliary tract diseases who underwent ERCP at Xuzhou Medical University from January 2020 to June 2023,divided into non-PEP(n=159)and PEP(n=24)groups based on PEP development.Baseline and intraoperative data were compared,and PEP-related factors examined via univariate and multivariate logistic regression.Using R,70%of patients were assigned to training and 30%to testing sets for PEP prediction model development.Model accuracy was evaluated using a calibration curve and receiver operating characteristic(ROC)area under the curve(AUC).RESULTS Age,total cholesterol level,history of pancreatitis,pancreatic ductography,bleeding,and intubation time differed significantly between the two groups when baseline data and intraoperative conditions were compared(P<0.05).Multifactorial logistic regression analysis demonstrated that age[odds ratio(OR)=0.192,95%confidence interval(CI):0.053-0.698],total cholesterol(OR=0.324,95%CI:0.152-0.694),history of pancreatitis(OR=6.159,95%CI:1.770-21.434),pancreatography(OR=3.726,95%CI:1.028-13.507),and bleeding(OR=3.059,95%CI:1.001-9.349)were independently associated with acute pancreatitis after ERCP.The predictive probabilities from the calibration curves had mean errors of 0.021 and 0.030,with ROC AUCs of 0.840 and 0.797 in the training and test sets,respectively.CONCLUSION Age,total cholesterol,pancreatitis history,pancreatic ductography,and bleeding influence the risk of acute PEP.A model incorporating these factors may aid early detection and intervention.展开更多
The following analysis is based on a multidimensional understanding of poverty using a nonmonetary basic needs approach. It is ground on data from the first survey on household living conditions for poverty assessment...The following analysis is based on a multidimensional understanding of poverty using a nonmonetary basic needs approach. It is ground on data from the first survey on household living conditions for poverty assessment, conducted by the National Institute of Statistics of Congo in 2005. Multiple Correspondence Analysis is applied to construct a composite indicator by aggregating several attributes likely to reflect the poverty of individuals or households. The application shows that Congolese households are not affected by the same type of poverty. Three types of non-monetary poverty are identified: infrastructure poverty, vulnerability of human existence and poverty of comfort. These households were then classified according to the composite indicator of Poverty. The results show that the incidence of poverty corresponds to the weight of poor class of about 70.67%.展开更多
Objective:To analyze the pathological characteristics of patients with transient cerebral ischemic attack(TIA)through multidimensional laboratory indicators and explore their clinical significance.Methods:Patients who...Objective:To analyze the pathological characteristics of patients with transient cerebral ischemic attack(TIA)through multidimensional laboratory indicators and explore their clinical significance.Methods:Patients who visited the outpa-tient department or were hospitalized in Rongxian Hospital of Traditional Chi-nese Medicine from January to December 2024 were selected.TIA patients were set as the experimental group(n=31),and healthy physical examination subjects were set as the control group(n=50).Multidimensional laboratory indicators such as blood routine,liver function,kidney function,blood lipids,electrolytes,hemorheology and blood glucose were detected and compared between the two groups.Results:In the experimental group,the WBC and NEUT#indexes in the blood routine were significantly different from those in the control group(P<0.05);the AST,AST/ALT,TP,GLO and A/G indexes in liver function were sig-nificantly different between the two groups(P<0.05);the K and CA indexes in electrolytes were significantly different between the two groups(P<0.05).Alt-hough there were differences in other indexes,they did not reach statistical sig-nificance.Conclusion:Multidimensional laboratory indicator detection is help-ful in revealing the pathological characteristics of TIA patients,and the abnormal changes of some indicators can provide an important reference for clinical diag-nosis,disease assessment and treatment.展开更多
文摘BACKGROUND Post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis is a common complication of the procedure.The effective prevention of post-ERCP pancreatitis(PEP)remains a key focus of clinical research.AIM To develop a prediction model for PEP based on multidimensional clinical indicators and evaluate its clinical application value.METHODS We retrospectively analyzed 183 patients with biliary tract diseases who underwent ERCP at Xuzhou Medical University from January 2020 to June 2023,divided into non-PEP(n=159)and PEP(n=24)groups based on PEP development.Baseline and intraoperative data were compared,and PEP-related factors examined via univariate and multivariate logistic regression.Using R,70%of patients were assigned to training and 30%to testing sets for PEP prediction model development.Model accuracy was evaluated using a calibration curve and receiver operating characteristic(ROC)area under the curve(AUC).RESULTS Age,total cholesterol level,history of pancreatitis,pancreatic ductography,bleeding,and intubation time differed significantly between the two groups when baseline data and intraoperative conditions were compared(P<0.05).Multifactorial logistic regression analysis demonstrated that age[odds ratio(OR)=0.192,95%confidence interval(CI):0.053-0.698],total cholesterol(OR=0.324,95%CI:0.152-0.694),history of pancreatitis(OR=6.159,95%CI:1.770-21.434),pancreatography(OR=3.726,95%CI:1.028-13.507),and bleeding(OR=3.059,95%CI:1.001-9.349)were independently associated with acute pancreatitis after ERCP.The predictive probabilities from the calibration curves had mean errors of 0.021 and 0.030,with ROC AUCs of 0.840 and 0.797 in the training and test sets,respectively.CONCLUSION Age,total cholesterol,pancreatitis history,pancreatic ductography,and bleeding influence the risk of acute PEP.A model incorporating these factors may aid early detection and intervention.
文摘The following analysis is based on a multidimensional understanding of poverty using a nonmonetary basic needs approach. It is ground on data from the first survey on household living conditions for poverty assessment, conducted by the National Institute of Statistics of Congo in 2005. Multiple Correspondence Analysis is applied to construct a composite indicator by aggregating several attributes likely to reflect the poverty of individuals or households. The application shows that Congolese households are not affected by the same type of poverty. Three types of non-monetary poverty are identified: infrastructure poverty, vulnerability of human existence and poverty of comfort. These households were then classified according to the composite indicator of Poverty. The results show that the incidence of poverty corresponds to the weight of poor class of about 70.67%.
文摘Objective:To analyze the pathological characteristics of patients with transient cerebral ischemic attack(TIA)through multidimensional laboratory indicators and explore their clinical significance.Methods:Patients who visited the outpa-tient department or were hospitalized in Rongxian Hospital of Traditional Chi-nese Medicine from January to December 2024 were selected.TIA patients were set as the experimental group(n=31),and healthy physical examination subjects were set as the control group(n=50).Multidimensional laboratory indicators such as blood routine,liver function,kidney function,blood lipids,electrolytes,hemorheology and blood glucose were detected and compared between the two groups.Results:In the experimental group,the WBC and NEUT#indexes in the blood routine were significantly different from those in the control group(P<0.05);the AST,AST/ALT,TP,GLO and A/G indexes in liver function were sig-nificantly different between the two groups(P<0.05);the K and CA indexes in electrolytes were significantly different between the two groups(P<0.05).Alt-hough there were differences in other indexes,they did not reach statistical sig-nificance.Conclusion:Multidimensional laboratory indicator detection is help-ful in revealing the pathological characteristics of TIA patients,and the abnormal changes of some indicators can provide an important reference for clinical diag-nosis,disease assessment and treatment.
