Deep neural networks(DNNs)are effective in solving both forward and inverse problems for nonlinear partial differential equations(PDEs).However,conventional DNNs are not effective in handling problems such as delay di...Deep neural networks(DNNs)are effective in solving both forward and inverse problems for nonlinear partial differential equations(PDEs).However,conventional DNNs are not effective in handling problems such as delay differential equations(DDEs)and delay integrodifferential equations(DIDEs)with constant delays,primarily due to their low regularity at delayinduced breaking points.In this paper,a DNN method that combines multi-task learning(MTL)which is proposed to solve both the forward and inverse problems of DIDEs.The core idea of this approach is to divide the original equation into multiple tasks based on the delay,using auxiliary outputs to represent the integral terms,followed by the use of MTL to seamlessly incorporate the properties at the breaking points into the loss function.Furthermore,given the increased training dificulty associated with multiple tasks and outputs,we employ a sequential training scheme to reduce training complexity and provide reference solutions for subsequent tasks.This approach significantly enhances the approximation accuracy of solving DIDEs with DNNs,as demonstrated by comparisons with traditional DNN methods.We validate the effectiveness of this method through several numerical experiments,test various parameter sharing structures in MTL and compare the testing results of these structures.Finally,this method is implemented to solve the inverse problem of nonlinear DIDE and the results show that the unknown parameters of DIDE can be discovered with sparse or noisy data.展开更多
Quantum error correction is a technique that enhances a system’s ability to combat noise by encoding logical information into additional quantum bits,which plays a key role in building practical quantum computers.The...Quantum error correction is a technique that enhances a system’s ability to combat noise by encoding logical information into additional quantum bits,which plays a key role in building practical quantum computers.The XZZX surface code,with only one stabilizer generator on each face,demonstrates significant application potential under biased noise.However,the existing minimum weight perfect matching(MWPM)algorithm has high computational complexity and lacks flexibility in large-scale systems.Therefore,this paper proposes a decoding method that combines graph neural networks(GNN)with multi-classifiers,the syndrome is transformed into an undirected graph,and the features are aggregated by convolutional layers,providing a more efficient and accurate decoding strategy.In the experiments,we evaluated the performance of the XZZX code under different biased noise conditions(bias=1,20,200)and different code distances(d=3,5,7,9,11).The experimental results show that under low bias noise(bias=1),the GNN decoder achieves a threshold of 0.18386,an improvement of approximately 19.12%compared to the MWPM decoder.Under high bias noise(bias=200),the GNN decoder reaches a threshold of 0.40542,improving by approximately 20.76%,overcoming the limitations of the conventional decoder.They demonstrate that the GNN decoding method exhibits superior performance and has broad application potential in the error correction of XZZX code.展开更多
BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes tha...BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes that may relate to NSSI through distinct psychological mechanisms.However,how these subtypes interact with specific NSSI behaviors remains unclear.AIM To examine associations between rumination subtypes and specific NSSI behaviors in adolescents.METHODS We conducted a cross-sectional study with 305 hospitalized adolescents diagnosed with depressive disorders.The subjects ranged from 12-18 years in age.Rumi-nation subtypes were assessed using the Ruminative Response Scale,and 12 NSSI behaviors were evaluated using a validated questionnaire.Network analysis was applied to explore symptom-level associations and identify central symptoms.RESULTS The network analysis revealed close connections between rumination subtypes and NSSI behaviors.Brooding was linked to behaviors such as hitting objects and burning.Scratching emerged as the most influential NSSI symptom.Symptomfocused rumination served as a key bridge connecting rumination and NSSI.CONCLUSION Symptom-focused rumination and scratching were identified as potential intervention targets.These findings highlight the psychological significance of specific cognitive-behavioral links in adolescent depression and suggest directions for tailored prevention and treatment.However,the cross-sectional,single-site design limits causal inference and generalizability.Future longitudinal and multi-center studies are needed to confirm causal pathways and verify the generalizability of the findings to broader adolescent populations.展开更多
Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY o...Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY on AD.Methods:The DNFB-induced mouse models of AD were established to investigate the therapeutic effects of WQY on AD.The symptoms of AD in the ears and backs of the mice were assessed,while inflammatory factors in the ear were quantified using quantitative real-time-polymerase chain reaction(qRT-PCR),and the percentages of CD4^(+)and CD8^(+)cells in the spleen were analyzed through flow cytometry.The compounds in WQY were identified using ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)analysis and the key targets and pathways of WQY to treat AD were predicted by network pharmacology.Subsequently,the key genes were tested and verified by qRT-PCR,and the potential active components and target proteins were verified by molecular docking.Results:WQY relieved the AD symptoms and histopathological injuries in the ear and back skin of mice with AD.Meanwhile,WQY significantly reduced the levels of inflammatory factors IL-6 and IL-1βin ear tissue,as well as the ratio of CD4^(+)/CD8^(+)cells in spleen.Additionally,a total of 142 compounds were identified from the water extract of WQY by UPLC-Orbitrap-MS/MS.39 key targets related to AD were screened out by network pharmacology methods.The KEGG analysis indicated that the effects of WQY were primarily mediated through pathways associated with Toll-like receptor signaling and T cell receptor signaling.Moreover,the results of qRT-PCR demonstrated that WQY significantly reduced the mRNA expressions of IL-4,IL-10,GATA3 and FOXP3,and molecular docking simulation verified that the active components of WQY had excellent binding abilities with IL-4,IL-10,GATA3 and FOXP3 proteins.Conclusion:The present study demonstrated that WQY effectively relieved AD symptoms in mice,decreased the inflammatory factors levels,regulated the balance of CD4^(+)and CD8^(+)cells,and the mechanism may be associated with the suppression of Th2 and Treg cell immune responses.展开更多
This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for ...This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.展开更多
The global nuclear mass based on the macroscopic-microscopic model was studied by applying a newly designed multi-task learning artificial neural network(MTL-ANN). First, the reported nuclear binding energies of 2095 ...The global nuclear mass based on the macroscopic-microscopic model was studied by applying a newly designed multi-task learning artificial neural network(MTL-ANN). First, the reported nuclear binding energies of 2095 nuclei(Z ≥ 8, N ≥ 8) released in the latest Atomic Mass Evaluation AME2020 and the deviations between the fitting result of the liquid drop model(LDM)and data from AME2020 for each nucleus were obtained.To compensate for the deviations and investigate the possible ignored physics in the LDM, the MTL-ANN method was introduced in the model. Compared to the single-task learning(STL) method, this new network has a powerful ability to simultaneously learn multi-nuclear properties,such as the binding energies and single neutron and proton separation energies. Moreover, it is highly effective in reducing the risk of overfitting and achieving better predictions. Consequently, good predictions can be obtained using this nuclear mass model for both the training and validation datasets and for the testing dataset. In detail, the global root mean square(RMS) of the binding energy is effectively reduced from approximately 2.4 MeV of LDM to the current 0.2 MeV, and the RMS of Sn, Spcan also reach approximately 0.2 MeV. Moreover, compared to STL, for the training and validation sets, 3-9% improvement can be achieved with the binding energy, and 20-30% improvement for S_(n), S_(p);for the testing sets, the reduction in deviations can even reach 30-40%, which significantly illustrates the advantage of the current MTL.展开更多
With the rapid development of the mobile Internet,users generate massive data in different forms in social network every day,and different characteristics of users are reflected by these social media data.How to integ...With the rapid development of the mobile Internet,users generate massive data in different forms in social network every day,and different characteristics of users are reflected by these social media data.How to integrate multiple heterogeneous information and establish user profiles from multiple perspectives plays an important role in providing personalized services,marketing,and recommendation systems.In this paper,we propose Multi-source&Multi-task Learning for User Profiles in Social Network which integrates multiple social data sources and contains a multi-task learning framework to simultaneously predict various attributes of a user.Firstly,we design their own feature extraction models for multiple heterogeneous data sources.Secondly,we design a shared layer to fuse multiple heterogeneous data sources as general shared representation for multi-task learning.Thirdly,we design each task’s own unique presentation layer for discriminant output of specific-task.Finally,we design a weighted loss function to improve the learning efficiency and prediction accuracy of each task.Our experimental results on more than 5000 Sina Weibo users demonstrate that our approach outperforms state-of-the-art baselines for inferring gender,age and region of social media users.展开更多
This paper proposes a universal framework,termed as Multi-Task Hybrid Convolutional Neural Network(MHCNN),for joint face detection,facial landmark detection,facial quality,and facial attribute analysis.MHCNN consists ...This paper proposes a universal framework,termed as Multi-Task Hybrid Convolutional Neural Network(MHCNN),for joint face detection,facial landmark detection,facial quality,and facial attribute analysis.MHCNN consists of a high-accuracy single stage detector(SSD)and an efficient tiny convolutional neural network(T-CNN)for joint face detection refinement,alignment and attribute analysis.Though the SSD face detectors achieve promising results,we find that applying a tiny CNN on detections further boosts the detected face scores and bounding boxes.By multi-task training,our T-CNN aims to provide five facial landmarks,facial quality scores,and facial attributes like wearing sunglasses and wearing masks.Since there is no public facial quality data and facial attribute data as we need,we contribute two datasets,namely FaceQ and FaceA,which are collected from the Internet.Experiments show that our MHCNN achieves face detection performance comparable to the state of the art in face detection data set and benchmark(FDDB),and gets reasonable results on AFLW,FaceQ and FaceA.展开更多
Spatio-temporal cellular network traffic prediction at wide-area level plays an important role in resource reconfiguration,traffic scheduling and intrusion detection,thus potentially supporting connected intelligence ...Spatio-temporal cellular network traffic prediction at wide-area level plays an important role in resource reconfiguration,traffic scheduling and intrusion detection,thus potentially supporting connected intelligence of the sixth generation of mobile communications technology(6G).However,the existing studies just focus on the spatio-temporal modeling of traffic data of single network service,such as short message,call,or Internet.It is not conducive to accurate prediction of traffic data,characterised by diverse network service,spatio-temporality and supersize volume.To address this issue,a novel multi-task deep learning framework is developed for citywide cellular network traffic prediction.Functionally,this framework mainly consists of a dual modular feature sharing layer and a multi-task learning layer(DMFS-MT).The former aims at mining long-term spatio-temporal dependencies and local spatio-temporal fluctuation trends in data,respectively,via a new combination of convolutional gated recurrent unit(ConvGRU)and 3-dimensional convolutional neural network(3D-CNN).For the latter,each task is performed for predicting service-specific traffic data based on a fully connected network.On the real-world Telecom Italia dataset,simulation results demonstrate the effectiveness of our proposal through prediction performance measure,spatial pattern comparison and statistical distribution verification.展开更多
Unmanned Aerial Vehicles(UAVs)cooperative multi-task system has become the research focus in recent years.However,the existing network frameworks of UAVs are not flexible and efficient enough to deal with the complex ...Unmanned Aerial Vehicles(UAVs)cooperative multi-task system has become the research focus in recent years.However,the existing network frameworks of UAVs are not flexible and efficient enough to deal with the complex multi-task scheduling,because they are not able to perceive the different features.In this paper,a novel cooperated UAVs network framework for multi-task scheduling is proposed.It is a three-layer network including a core layer,an aggregation layer and an execution layer,which enhances the efficiency of multi-task distribution,aggregation and transmission.Furthermore,an Aggre Gate Flow(AGFlow)based scheduler is dedicatedly designed to maximize the task completion rate,whose key point is to aggregate flows belonging to one task during the multi-task transmission of UAVs network and to allocate priority by calculating the urgency-level of each AGFlow.Simulation results demonstrate that,compared with that of state-of-the-art scheduler,the average task completion rate of AGFlow based scheduler is raised by 0.278.展开更多
Traffic characterization(e.g.,chat,video)and application identifi-cation(e.g.,FTP,Facebook)are two of the more crucial jobs in encrypted network traffic classification.These two activities are typically carried out se...Traffic characterization(e.g.,chat,video)and application identifi-cation(e.g.,FTP,Facebook)are two of the more crucial jobs in encrypted network traffic classification.These two activities are typically carried out separately by existing systems using separate models,significantly adding to the difficulty of network administration.Convolutional Neural Network(CNN)and Transformer are deep learning-based approaches for network traf-fic classification.CNN is good at extracting local features while ignoring long-distance information from the network traffic sequence,and Transformer can capture long-distance feature dependencies while ignoring local details.Based on these characteristics,a multi-task learning model that combines Transformer and 1D-CNN for encrypted traffic classification is proposed(MTC).In order to make up for the Transformer’s lack of local detail feature extraction capability and the 1D-CNN’s shortcoming of ignoring long-distance correlation information when processing traffic sequences,the model uses a parallel structure to fuse the features generated by the Transformer block and the 1D-CNN block with each other using a feature fusion block.This structure improved the representation of traffic features by both blocks and allows the model to perform well with both long and short length sequences.The model simultaneously handles multiple tasks,which lowers the cost of training.Experiments reveal that on the ISCX VPN-nonVPN dataset,the model achieves an average F1 score of 98.25%and an average recall of 98.30%for the task of identifying applications,and an average F1 score of 97.94%,and an average recall of 97.54%for the task of traffic characterization.When advanced models on the same dataset are chosen for comparison,the model produces the best results.To prove the generalization,we applied MTC to CICIDS2017 dataset,and our model also achieved good results.展开更多
Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body.Recently,efforts have been made to alleviate the discomfort associated with invasive medical procedures through the u...Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body.Recently,efforts have been made to alleviate the discomfort associated with invasive medical procedures through the use of virtual reality(VR)technology.VR has been demonstrated to be an effective treatment for pain associated with medical procedures,as well as for chronic pain conditions for which no effective treatment has been established.The precise mechanism by which the diversion from reality facilitated by VR contributes to the diminution of pain and anxiety has yet to be elucidated.However,the provision of positive images through VR-based visual stimulation may enhance the functionality of brain networks.The salience network is diminished,while the default mode network is enhanced.Additionally,the medial prefrontal cortex may establish a stronger connection with the default mode network,which could result in a reduction of pain and anxiety.Further research into the potential of VR technology to alleviate pain could lead to a reduction in the number of individuals who overdose on painkillers and contribute to positive change in the medical field.展开更多
The direction-of-arrival(DoA) estimation is one of the hot research areas in signal processing. To overcome the DoA estimation challenge without the prior information about signal sources number and multipath number i...The direction-of-arrival(DoA) estimation is one of the hot research areas in signal processing. To overcome the DoA estimation challenge without the prior information about signal sources number and multipath number in millimeter wave system,the multi-task deep residual shrinkage network(MTDRSN) and transfer learning-based convolutional neural network(TCNN), namely MDTCNet, are proposed. The sampling covariance matrix based on the received signal is used as the input to the proposed network. A DRSN-based multi-task classifications model is first introduced to estimate signal sources number and multipath number simultaneously. Then, the DoAs with multi-signal and multipath are estimated by the regression model. The proposed CNN is applied for DoAs estimation with the predicted number of signal sources and paths. Furthermore, the modelbased transfer learning is also introduced into the regression model. The TCNN inherits the partial network parameters of the already formed optimization model obtained by the CNN. A series of experimental results show that the MDTCNet-based DoAs estimation method can accurately predict the signal sources number and multipath number under a range of signal-to-noise ratios. Remarkably, the proposed method achieves the lower root mean square error compared with some existing deep learning-based and traditional methods.展开更多
Complex network models are frequently employed for simulating and studyingdiverse real-world complex systems.Among these models,scale-free networks typically exhibit greater fragility to malicious attacks.Consequently...Complex network models are frequently employed for simulating and studyingdiverse real-world complex systems.Among these models,scale-free networks typically exhibit greater fragility to malicious attacks.Consequently,enhancing the robustness of scale-free networks has become a pressing issue.To address this problem,this paper proposes a Multi-Granularity Integration Algorithm(MGIA),which aims to improve the robustness of scale-free networks while keeping the initial degree of each node unchanged,ensuring network connectivity and avoiding the generation of multiple edges.The algorithm generates a multi-granularity structure from the initial network to be optimized,then uses different optimization strategies to optimize the networks at various granular layers in this structure,and finally realizes the information exchange between different granular layers,thereby further enhancing the optimization effect.We propose new network refresh,crossover,and mutation operators to ensure that the optimized network satisfies the given constraints.Meanwhile,we propose new network similarity and network dissimilarity evaluation metrics to improve the effectiveness of the optimization operators in the algorithm.In the experiments,the MGIA enhances the robustness of the scale-free network by 67.6%.This improvement is approximately 17.2%higher than the optimization effects achieved by eight currently existing complex network robustness optimization algorithms.展开更多
Satellite edge computing has garnered significant attention from researchers;however,processing a large volume of tasks within multi-node satellite networks still poses considerable challenges.The sharp increase in us...Satellite edge computing has garnered significant attention from researchers;however,processing a large volume of tasks within multi-node satellite networks still poses considerable challenges.The sharp increase in user demand for latency-sensitive tasks has inevitably led to offloading bottlenecks and insufficient computational capacity on individual satellite edge servers,making it necessary to implement effective task offloading scheduling to enhance user experience.In this paper,we propose a priority-based task scheduling strategy based on a Software-Defined Network(SDN)framework for satellite-terrestrial integrated networks,which clarifies the execution order of tasks based on their priority.Subsequently,we apply a Dueling-Double Deep Q-Network(DDQN)algorithm enhanced with prioritized experience replay to derive a computation offloading strategy,improving the experience replay mechanism within the Dueling-DDQN framework.Next,we utilize the Deep Deterministic Policy Gradient(DDPG)algorithm to determine the optimal resource allocation strategy to reduce the processing latency of sub-tasks.Simulation results demonstrate that the proposed d3-DDPG algorithm outperforms other approaches,effectively reducing task processing latency and thus improving user experience and system efficiency.展开更多
Cooperative multi-agent reinforcement learning(MARL)is a key technology for enabling cooperation in complex multi-agent systems.It has achieved remarkable progress in areas such as gaming,autonomous driving,and multi-...Cooperative multi-agent reinforcement learning(MARL)is a key technology for enabling cooperation in complex multi-agent systems.It has achieved remarkable progress in areas such as gaming,autonomous driving,and multi-robot control.Empowering cooperative MARL with multi-task decision-making capabilities is expected to further broaden its application scope.In multi-task scenarios,cooperative MARL algorithms need to address 3 types of multi-task problems:reward-related multi-task,arising from different reward functions;multi-domain multi-task,caused by differences in state and action spaces,state transition functions;and scalability-related multi-task,resulting from the dynamic variation in the number of agents.Most existing studies focus on scalability-related multitask problems.However,with the increasing integration between large language models(LLMs)and multi-agent systems,a growing number of LLM-based multi-agent systems have emerged,enabling more complex multi-task cooperation.This paper provides a comprehensive review of the latest advances in this field.By combining multi-task reinforcement learning with cooperative MARL,we categorize and analyze the 3 major types of multi-task problems under multi-agent settings,offering more fine-grained classifications and summarizing key insights for each.In addition,we summarize commonly used benchmarks and discuss future directions of research in this area,which hold promise for further enhancing the multi-task cooperation capabilities of multi-agent systems and expanding their practical applications in the real world.展开更多
The accurate prediction of drug absorption,distribution,metabolism,excretion,and toxicity(ADMET)properties represents a crucial step in early drug development for reducing failure risk.Current deep learning approaches...The accurate prediction of drug absorption,distribution,metabolism,excretion,and toxicity(ADMET)properties represents a crucial step in early drug development for reducing failure risk.Current deep learning approaches face challenges with data sparsity and information loss due to single-molecule representation limitations and isolated predictive tasks.This research proposes molecular properties prediction with parallel-view and collaborative learning(MolP-PC),a multi-view fusion and multi-task deep learning framework that integrates 1D molecular fingerprints(MFs),2D molecular graphs,and 3D geometric representations,incorporating an attention-gated fusion mechanism and multi-task adaptive learning strategy for precise ADMET property predictions.Experimental results demonstrate that MolP-PC achieves optimal performance in 27 of 54 tasks,with its multi-task learning(MTL)mechanism significantly enhancing predictive performance on small-scale datasets and surpassing single-task models in 41 of 54 tasks.Additional ablation studies and interpretability analyses confirm the significance of multi-view fusion in capturing multi-dimensional molecular information and enhancing model generalization.A case study examining the anticancer compound Oroxylin A demonstrates MolP-PC’s effective generalization in predicting key pharmacokinetic parameters such as half-life(T0.5)and clearance(CL),indicating its practical utility in drug modeling.However,the model exhibits a tendency to underestimate volume of distribution(VD),indicating potential for improvement in analyzing compounds with high tissue distribution.This study presents an efficient and interpretable approach for ADMET property prediction,establishing a novel framework for molecular optimization and risk assessment in drug development.展开更多
Two-dimensional endoscopic images are susceptible to interferences such as specular reflections and monotonous texture illumination,hindering accurate three-dimensional lesion reconstruction by surgical robots.This st...Two-dimensional endoscopic images are susceptible to interferences such as specular reflections and monotonous texture illumination,hindering accurate three-dimensional lesion reconstruction by surgical robots.This study proposes a novel end-to-end disparity estimation model to address these challenges.Our approach combines a Pseudo-Siamese neural network architecture with pyramid dilated convolutions,integrating multi-scale image information to enhance robustness against lighting interferences.This study introduces a Pseudo-Siamese structure-based disparity regression model that simplifies left-right image comparison,improving accuracy and efficiency.The model was evaluated using a dataset of stereo endoscopic videos captured by the Da Vinci surgical robot,comprising simulated silicone heart sequences and real heart video data.Experimental results demonstrate significant improvement in the network’s resistance to lighting interference without substantially increasing parameters.Moreover,the model exhibited faster convergence during training,contributing to overall performance enhancement.This study advances endoscopic image processing accuracy and has potential implications for surgical robot applications in complex environments.展开更多
文摘Deep neural networks(DNNs)are effective in solving both forward and inverse problems for nonlinear partial differential equations(PDEs).However,conventional DNNs are not effective in handling problems such as delay differential equations(DDEs)and delay integrodifferential equations(DIDEs)with constant delays,primarily due to their low regularity at delayinduced breaking points.In this paper,a DNN method that combines multi-task learning(MTL)which is proposed to solve both the forward and inverse problems of DIDEs.The core idea of this approach is to divide the original equation into multiple tasks based on the delay,using auxiliary outputs to represent the integral terms,followed by the use of MTL to seamlessly incorporate the properties at the breaking points into the loss function.Furthermore,given the increased training dificulty associated with multiple tasks and outputs,we employ a sequential training scheme to reduce training complexity and provide reference solutions for subsequent tasks.This approach significantly enhances the approximation accuracy of solving DIDEs with DNNs,as demonstrated by comparisons with traditional DNN methods.We validate the effectiveness of this method through several numerical experiments,test various parameter sharing structures in MTL and compare the testing results of these structures.Finally,this method is implemented to solve the inverse problem of nonlinear DIDE and the results show that the unknown parameters of DIDE can be discovered with sparse or noisy data.
基金supported by the Natural Science Foundation of Shandong Province,China(Grant No.ZR2021MF049)the Joint Fund of Natural Science Foundation of Shandong Province,China(Grant Nos.ZR2022LL.Z012 and ZR2021LLZ001)the Key Research and Development Program of Shandong Province,China(Grant No.2023CXGC010901).
文摘Quantum error correction is a technique that enhances a system’s ability to combat noise by encoding logical information into additional quantum bits,which plays a key role in building practical quantum computers.The XZZX surface code,with only one stabilizer generator on each face,demonstrates significant application potential under biased noise.However,the existing minimum weight perfect matching(MWPM)algorithm has high computational complexity and lacks flexibility in large-scale systems.Therefore,this paper proposes a decoding method that combines graph neural networks(GNN)with multi-classifiers,the syndrome is transformed into an undirected graph,and the features are aggregated by convolutional layers,providing a more efficient and accurate decoding strategy.In the experiments,we evaluated the performance of the XZZX code under different biased noise conditions(bias=1,20,200)and different code distances(d=3,5,7,9,11).The experimental results show that under low bias noise(bias=1),the GNN decoder achieves a threshold of 0.18386,an improvement of approximately 19.12%compared to the MWPM decoder.Under high bias noise(bias=200),the GNN decoder reaches a threshold of 0.40542,improving by approximately 20.76%,overcoming the limitations of the conventional decoder.They demonstrate that the GNN decoding method exhibits superior performance and has broad application potential in the error correction of XZZX code.
基金Supported by Key Research and Development Program of Shaanxi Province,China,No.2024SF-YBXM-078.
文摘BACKGROUND Non-suicidal self-injury(NSSI)is common among adolescents with depressive disorders and poses a major public health challenge.Rumination,a key cognitive feature of depression,includes different subtypes that may relate to NSSI through distinct psychological mechanisms.However,how these subtypes interact with specific NSSI behaviors remains unclear.AIM To examine associations between rumination subtypes and specific NSSI behaviors in adolescents.METHODS We conducted a cross-sectional study with 305 hospitalized adolescents diagnosed with depressive disorders.The subjects ranged from 12-18 years in age.Rumi-nation subtypes were assessed using the Ruminative Response Scale,and 12 NSSI behaviors were evaluated using a validated questionnaire.Network analysis was applied to explore symptom-level associations and identify central symptoms.RESULTS The network analysis revealed close connections between rumination subtypes and NSSI behaviors.Brooding was linked to behaviors such as hitting objects and burning.Scratching emerged as the most influential NSSI symptom.Symptomfocused rumination served as a key bridge connecting rumination and NSSI.CONCLUSION Symptom-focused rumination and scratching were identified as potential intervention targets.These findings highlight the psychological significance of specific cognitive-behavioral links in adolescent depression and suggest directions for tailored prevention and treatment.However,the cross-sectional,single-site design limits causal inference and generalizability.Future longitudinal and multi-center studies are needed to confirm causal pathways and verify the generalizability of the findings to broader adolescent populations.
基金supported by grants from the National Natural Science Foundation of China(82004252)the Project of Administration of Traditional Chinese Medicine of Guangdong Province(202405112017596500)the Basic and Applied Basic Research Foundation of Guangzhou Municipal Science and Technology Bureau(202102020533).
文摘Background:Wenqing Yin(WQY)is a classic prescription used to treat skin diseases like atopic dermatitis(AD)in China,and the aim of this study is to investigate the therapeutic effects and molecular mechanisms of WQY on AD.Methods:The DNFB-induced mouse models of AD were established to investigate the therapeutic effects of WQY on AD.The symptoms of AD in the ears and backs of the mice were assessed,while inflammatory factors in the ear were quantified using quantitative real-time-polymerase chain reaction(qRT-PCR),and the percentages of CD4^(+)and CD8^(+)cells in the spleen were analyzed through flow cytometry.The compounds in WQY were identified using ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS)analysis and the key targets and pathways of WQY to treat AD were predicted by network pharmacology.Subsequently,the key genes were tested and verified by qRT-PCR,and the potential active components and target proteins were verified by molecular docking.Results:WQY relieved the AD symptoms and histopathological injuries in the ear and back skin of mice with AD.Meanwhile,WQY significantly reduced the levels of inflammatory factors IL-6 and IL-1βin ear tissue,as well as the ratio of CD4^(+)/CD8^(+)cells in spleen.Additionally,a total of 142 compounds were identified from the water extract of WQY by UPLC-Orbitrap-MS/MS.39 key targets related to AD were screened out by network pharmacology methods.The KEGG analysis indicated that the effects of WQY were primarily mediated through pathways associated with Toll-like receptor signaling and T cell receptor signaling.Moreover,the results of qRT-PCR demonstrated that WQY significantly reduced the mRNA expressions of IL-4,IL-10,GATA3 and FOXP3,and molecular docking simulation verified that the active components of WQY had excellent binding abilities with IL-4,IL-10,GATA3 and FOXP3 proteins.Conclusion:The present study demonstrated that WQY effectively relieved AD symptoms in mice,decreased the inflammatory factors levels,regulated the balance of CD4^(+)and CD8^(+)cells,and the mechanism may be associated with the suppression of Th2 and Treg cell immune responses.
基金supported by Istanbul Technical University(Project No.45698)supported through the“Young Researchers’Career Development Project-training of doctoral students”of the Croatian Science Foundation.
文摘This paper investigates the reliability of internal marine combustion engines using an integrated approach that combines Fault Tree Analysis(FTA)and Bayesian Networks(BN).FTA provides a structured,top-down method for identifying critical failure modes and their root causes,while BN introduces flexibility in probabilistic reasoning,enabling dynamic updates based on new evidence.This dual methodology overcomes the limitations of static FTA models,offering a comprehensive framework for system reliability analysis.Critical failures,including External Leakage(ELU),Failure to Start(FTS),and Overheating(OHE),were identified as key risks.By incorporating redundancy into high-risk components such as pumps and batteries,the likelihood of these failures was significantly reduced.For instance,redundant pumps reduced the probability of ELU by 31.88%,while additional batteries decreased the occurrence of FTS by 36.45%.The results underscore the practical benefits of combining FTA and BN for enhancing system reliability,particularly in maritime applications where operational safety and efficiency are critical.This research provides valuable insights for maintenance planning and highlights the importance of redundancy in critical systems,especially as the industry transitions toward more autonomous vessels.
基金supported by the National Natural Science Foundation of China(Nos.1187050492,12005303,and 12175170).
文摘The global nuclear mass based on the macroscopic-microscopic model was studied by applying a newly designed multi-task learning artificial neural network(MTL-ANN). First, the reported nuclear binding energies of 2095 nuclei(Z ≥ 8, N ≥ 8) released in the latest Atomic Mass Evaluation AME2020 and the deviations between the fitting result of the liquid drop model(LDM)and data from AME2020 for each nucleus were obtained.To compensate for the deviations and investigate the possible ignored physics in the LDM, the MTL-ANN method was introduced in the model. Compared to the single-task learning(STL) method, this new network has a powerful ability to simultaneously learn multi-nuclear properties,such as the binding energies and single neutron and proton separation energies. Moreover, it is highly effective in reducing the risk of overfitting and achieving better predictions. Consequently, good predictions can be obtained using this nuclear mass model for both the training and validation datasets and for the testing dataset. In detail, the global root mean square(RMS) of the binding energy is effectively reduced from approximately 2.4 MeV of LDM to the current 0.2 MeV, and the RMS of Sn, Spcan also reach approximately 0.2 MeV. Moreover, compared to STL, for the training and validation sets, 3-9% improvement can be achieved with the binding energy, and 20-30% improvement for S_(n), S_(p);for the testing sets, the reduction in deviations can even reach 30-40%, which significantly illustrates the advantage of the current MTL.
基金This work is supported by State Grid Science and Technology Project under Grant No.520613180002,62061318C002the Fundamental Research Funds for the Central Universities(Grant No.HIT.NSRIF.201714)+4 种基金Weihai Science and Technology Development Program(2016DXGJMS15)Key Research and Development Program in Shandong Provincial(2017GGX90103)Sanming Science and Technology Project,Grant No.2015-G-6,Shandong province vocational education educational reform research project.Grant No.2017209Study and Development of Smart Agriculture Control System Based on Spark Big Data Decision(2017N0029)Jiangsu Province industrial Communication Technology Application Technology Innovation Team Project.
文摘With the rapid development of the mobile Internet,users generate massive data in different forms in social network every day,and different characteristics of users are reflected by these social media data.How to integrate multiple heterogeneous information and establish user profiles from multiple perspectives plays an important role in providing personalized services,marketing,and recommendation systems.In this paper,we propose Multi-source&Multi-task Learning for User Profiles in Social Network which integrates multiple social data sources and contains a multi-task learning framework to simultaneously predict various attributes of a user.Firstly,we design their own feature extraction models for multiple heterogeneous data sources.Secondly,we design a shared layer to fuse multiple heterogeneous data sources as general shared representation for multi-task learning.Thirdly,we design each task’s own unique presentation layer for discriminant output of specific-task.Finally,we design a weighted loss function to improve the learning efficiency and prediction accuracy of each task.Our experimental results on more than 5000 Sina Weibo users demonstrate that our approach outperforms state-of-the-art baselines for inferring gender,age and region of social media users.
基金supported by ZTE Corporation and State Key Laboratory of Mobile Network and Mobile Multimedia Technology
文摘This paper proposes a universal framework,termed as Multi-Task Hybrid Convolutional Neural Network(MHCNN),for joint face detection,facial landmark detection,facial quality,and facial attribute analysis.MHCNN consists of a high-accuracy single stage detector(SSD)and an efficient tiny convolutional neural network(T-CNN)for joint face detection refinement,alignment and attribute analysis.Though the SSD face detectors achieve promising results,we find that applying a tiny CNN on detections further boosts the detected face scores and bounding boxes.By multi-task training,our T-CNN aims to provide five facial landmarks,facial quality scores,and facial attributes like wearing sunglasses and wearing masks.Since there is no public facial quality data and facial attribute data as we need,we contribute two datasets,namely FaceQ and FaceA,which are collected from the Internet.Experiments show that our MHCNN achieves face detection performance comparable to the state of the art in face detection data set and benchmark(FDDB),and gets reasonable results on AFLW,FaceQ and FaceA.
基金supported in part by the Science and Technology Project of Hebei Education Department(No.ZD2021088)in part by the S&T Major Project of the Science and Technology Ministry of China(No.2017YFE0135700)。
文摘Spatio-temporal cellular network traffic prediction at wide-area level plays an important role in resource reconfiguration,traffic scheduling and intrusion detection,thus potentially supporting connected intelligence of the sixth generation of mobile communications technology(6G).However,the existing studies just focus on the spatio-temporal modeling of traffic data of single network service,such as short message,call,or Internet.It is not conducive to accurate prediction of traffic data,characterised by diverse network service,spatio-temporality and supersize volume.To address this issue,a novel multi-task deep learning framework is developed for citywide cellular network traffic prediction.Functionally,this framework mainly consists of a dual modular feature sharing layer and a multi-task learning layer(DMFS-MT).The former aims at mining long-term spatio-temporal dependencies and local spatio-temporal fluctuation trends in data,respectively,via a new combination of convolutional gated recurrent unit(ConvGRU)and 3-dimensional convolutional neural network(3D-CNN).For the latter,each task is performed for predicting service-specific traffic data based on a fully connected network.On the real-world Telecom Italia dataset,simulation results demonstrate the effectiveness of our proposal through prediction performance measure,spatial pattern comparison and statistical distribution verification.
基金co-supported by the National Natural Science Foundation of China(Nos.61762030 and 61971148)the Guangxi Natural Science Foundation,China(Nos.2019GXNSFFA245007,2018GXNSFDA281013 and 2016GXNSFGA380002)Key Science and Technology Project of Guangxi,China(Nos.AA18242021,ZY19183005,2017AB13014,2018JJA70209,AA19110044 and AA19110046)。
文摘Unmanned Aerial Vehicles(UAVs)cooperative multi-task system has become the research focus in recent years.However,the existing network frameworks of UAVs are not flexible and efficient enough to deal with the complex multi-task scheduling,because they are not able to perceive the different features.In this paper,a novel cooperated UAVs network framework for multi-task scheduling is proposed.It is a three-layer network including a core layer,an aggregation layer and an execution layer,which enhances the efficiency of multi-task distribution,aggregation and transmission.Furthermore,an Aggre Gate Flow(AGFlow)based scheduler is dedicatedly designed to maximize the task completion rate,whose key point is to aggregate flows belonging to one task during the multi-task transmission of UAVs network and to allocate priority by calculating the urgency-level of each AGFlow.Simulation results demonstrate that,compared with that of state-of-the-art scheduler,the average task completion rate of AGFlow based scheduler is raised by 0.278.
基金supported by the People’s Public Security University of China central basic scientific research business program(No.2021JKF206).
文摘Traffic characterization(e.g.,chat,video)and application identifi-cation(e.g.,FTP,Facebook)are two of the more crucial jobs in encrypted network traffic classification.These two activities are typically carried out separately by existing systems using separate models,significantly adding to the difficulty of network administration.Convolutional Neural Network(CNN)and Transformer are deep learning-based approaches for network traf-fic classification.CNN is good at extracting local features while ignoring long-distance information from the network traffic sequence,and Transformer can capture long-distance feature dependencies while ignoring local details.Based on these characteristics,a multi-task learning model that combines Transformer and 1D-CNN for encrypted traffic classification is proposed(MTC).In order to make up for the Transformer’s lack of local detail feature extraction capability and the 1D-CNN’s shortcoming of ignoring long-distance correlation information when processing traffic sequences,the model uses a parallel structure to fuse the features generated by the Transformer block and the 1D-CNN block with each other using a feature fusion block.This structure improved the representation of traffic features by both blocks and allows the model to perform well with both long and short length sequences.The model simultaneously handles multiple tasks,which lowers the cost of training.Experiments reveal that on the ISCX VPN-nonVPN dataset,the model achieves an average F1 score of 98.25%and an average recall of 98.30%for the task of identifying applications,and an average F1 score of 97.94%,and an average recall of 97.54%for the task of traffic characterization.When advanced models on the same dataset are chosen for comparison,the model produces the best results.To prove the generalization,we applied MTC to CICIDS2017 dataset,and our model also achieved good results.
文摘Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body.Recently,efforts have been made to alleviate the discomfort associated with invasive medical procedures through the use of virtual reality(VR)technology.VR has been demonstrated to be an effective treatment for pain associated with medical procedures,as well as for chronic pain conditions for which no effective treatment has been established.The precise mechanism by which the diversion from reality facilitated by VR contributes to the diminution of pain and anxiety has yet to be elucidated.However,the provision of positive images through VR-based visual stimulation may enhance the functionality of brain networks.The salience network is diminished,while the default mode network is enhanced.Additionally,the medial prefrontal cortex may establish a stronger connection with the default mode network,which could result in a reduction of pain and anxiety.Further research into the potential of VR technology to alleviate pain could lead to a reduction in the number of individuals who overdose on painkillers and contribute to positive change in the medical field.
基金funded by Beijing University of Posts and Telecommunications-China Mobile Research Institute Joint Innovation Center。
文摘The direction-of-arrival(DoA) estimation is one of the hot research areas in signal processing. To overcome the DoA estimation challenge without the prior information about signal sources number and multipath number in millimeter wave system,the multi-task deep residual shrinkage network(MTDRSN) and transfer learning-based convolutional neural network(TCNN), namely MDTCNet, are proposed. The sampling covariance matrix based on the received signal is used as the input to the proposed network. A DRSN-based multi-task classifications model is first introduced to estimate signal sources number and multipath number simultaneously. Then, the DoAs with multi-signal and multipath are estimated by the regression model. The proposed CNN is applied for DoAs estimation with the predicted number of signal sources and paths. Furthermore, the modelbased transfer learning is also introduced into the regression model. The TCNN inherits the partial network parameters of the already formed optimization model obtained by the CNN. A series of experimental results show that the MDTCNet-based DoAs estimation method can accurately predict the signal sources number and multipath number under a range of signal-to-noise ratios. Remarkably, the proposed method achieves the lower root mean square error compared with some existing deep learning-based and traditional methods.
基金National Natural Science Foundation of China(11971211,12171388).
文摘Complex network models are frequently employed for simulating and studyingdiverse real-world complex systems.Among these models,scale-free networks typically exhibit greater fragility to malicious attacks.Consequently,enhancing the robustness of scale-free networks has become a pressing issue.To address this problem,this paper proposes a Multi-Granularity Integration Algorithm(MGIA),which aims to improve the robustness of scale-free networks while keeping the initial degree of each node unchanged,ensuring network connectivity and avoiding the generation of multiple edges.The algorithm generates a multi-granularity structure from the initial network to be optimized,then uses different optimization strategies to optimize the networks at various granular layers in this structure,and finally realizes the information exchange between different granular layers,thereby further enhancing the optimization effect.We propose new network refresh,crossover,and mutation operators to ensure that the optimized network satisfies the given constraints.Meanwhile,we propose new network similarity and network dissimilarity evaluation metrics to improve the effectiveness of the optimization operators in the algorithm.In the experiments,the MGIA enhances the robustness of the scale-free network by 67.6%.This improvement is approximately 17.2%higher than the optimization effects achieved by eight currently existing complex network robustness optimization algorithms.
文摘Satellite edge computing has garnered significant attention from researchers;however,processing a large volume of tasks within multi-node satellite networks still poses considerable challenges.The sharp increase in user demand for latency-sensitive tasks has inevitably led to offloading bottlenecks and insufficient computational capacity on individual satellite edge servers,making it necessary to implement effective task offloading scheduling to enhance user experience.In this paper,we propose a priority-based task scheduling strategy based on a Software-Defined Network(SDN)framework for satellite-terrestrial integrated networks,which clarifies the execution order of tasks based on their priority.Subsequently,we apply a Dueling-Double Deep Q-Network(DDQN)algorithm enhanced with prioritized experience replay to derive a computation offloading strategy,improving the experience replay mechanism within the Dueling-DDQN framework.Next,we utilize the Deep Deterministic Policy Gradient(DDPG)algorithm to determine the optimal resource allocation strategy to reduce the processing latency of sub-tasks.Simulation results demonstrate that the proposed d3-DDPG algorithm outperforms other approaches,effectively reducing task processing latency and thus improving user experience and system efficiency.
基金The National Natural Science Foundation of China(62136008,62293541)The Beijing Natural Science Foundation(4232056)The Beijing Nova Program(20240484514).
文摘Cooperative multi-agent reinforcement learning(MARL)is a key technology for enabling cooperation in complex multi-agent systems.It has achieved remarkable progress in areas such as gaming,autonomous driving,and multi-robot control.Empowering cooperative MARL with multi-task decision-making capabilities is expected to further broaden its application scope.In multi-task scenarios,cooperative MARL algorithms need to address 3 types of multi-task problems:reward-related multi-task,arising from different reward functions;multi-domain multi-task,caused by differences in state and action spaces,state transition functions;and scalability-related multi-task,resulting from the dynamic variation in the number of agents.Most existing studies focus on scalability-related multitask problems.However,with the increasing integration between large language models(LLMs)and multi-agent systems,a growing number of LLM-based multi-agent systems have emerged,enabling more complex multi-task cooperation.This paper provides a comprehensive review of the latest advances in this field.By combining multi-task reinforcement learning with cooperative MARL,we categorize and analyze the 3 major types of multi-task problems under multi-agent settings,offering more fine-grained classifications and summarizing key insights for each.In addition,we summarize commonly used benchmarks and discuss future directions of research in this area,which hold promise for further enhancing the multi-task cooperation capabilities of multi-agent systems and expanding their practical applications in the real world.
基金supported by the research on key technologies for monitoring and identifying drug abuse of anesthetic drugs and psychotropic drugs,and intervention for addiction(No.2023YFC3304200)the program of a study on the diagnosis of addiction to synthetic cannabinoids and methods of assessing the risk of abuse(No.2022YFC3300905)+1 种基金the program of Ab initio design and generation of AI models for small molecule ligands based on target structures(No.2022PE0AC03)ZHIJIANG LAB.
文摘The accurate prediction of drug absorption,distribution,metabolism,excretion,and toxicity(ADMET)properties represents a crucial step in early drug development for reducing failure risk.Current deep learning approaches face challenges with data sparsity and information loss due to single-molecule representation limitations and isolated predictive tasks.This research proposes molecular properties prediction with parallel-view and collaborative learning(MolP-PC),a multi-view fusion and multi-task deep learning framework that integrates 1D molecular fingerprints(MFs),2D molecular graphs,and 3D geometric representations,incorporating an attention-gated fusion mechanism and multi-task adaptive learning strategy for precise ADMET property predictions.Experimental results demonstrate that MolP-PC achieves optimal performance in 27 of 54 tasks,with its multi-task learning(MTL)mechanism significantly enhancing predictive performance on small-scale datasets and surpassing single-task models in 41 of 54 tasks.Additional ablation studies and interpretability analyses confirm the significance of multi-view fusion in capturing multi-dimensional molecular information and enhancing model generalization.A case study examining the anticancer compound Oroxylin A demonstrates MolP-PC’s effective generalization in predicting key pharmacokinetic parameters such as half-life(T0.5)and clearance(CL),indicating its practical utility in drug modeling.However,the model exhibits a tendency to underestimate volume of distribution(VD),indicating potential for improvement in analyzing compounds with high tissue distribution.This study presents an efficient and interpretable approach for ADMET property prediction,establishing a novel framework for molecular optimization and risk assessment in drug development.
基金Supported by Sichuan Science and Technology Program(2023YFSY0026,2023YFH0004)Supported by the Institute of Information&Communications Technology Planning&Evaluation(IITP)grant funded by the Korean government(MSIT)(No.RS-2022-00155885,Artificial Intelligence Convergence Innovation Human Resources Development(Hanyang University ERICA)).
文摘Two-dimensional endoscopic images are susceptible to interferences such as specular reflections and monotonous texture illumination,hindering accurate three-dimensional lesion reconstruction by surgical robots.This study proposes a novel end-to-end disparity estimation model to address these challenges.Our approach combines a Pseudo-Siamese neural network architecture with pyramid dilated convolutions,integrating multi-scale image information to enhance robustness against lighting interferences.This study introduces a Pseudo-Siamese structure-based disparity regression model that simplifies left-right image comparison,improving accuracy and efficiency.The model was evaluated using a dataset of stereo endoscopic videos captured by the Da Vinci surgical robot,comprising simulated silicone heart sequences and real heart video data.Experimental results demonstrate significant improvement in the network’s resistance to lighting interference without substantially increasing parameters.Moreover,the model exhibited faster convergence during training,contributing to overall performance enhancement.This study advances endoscopic image processing accuracy and has potential implications for surgical robot applications in complex environments.
