Surface polaritons,as surface electromagnetic waves propagating along the surface of a medium,have played a crucial role in enhancing photonic spin Hall effect(PSHE)and developing highly sensitive refractive index(RI)...Surface polaritons,as surface electromagnetic waves propagating along the surface of a medium,have played a crucial role in enhancing photonic spin Hall effect(PSHE)and developing highly sensitive refractive index(RI)sensors.Among them,the traditional surface plasmon polariton(SPP)based on noble metals limits its application beyond the near-infrared(IR)regime due to the large negative permittivity and optical losses.In this contribution,we theoretically proposed a highly sensitive PSHE sensor with the structure of Ge prism-SiC-Si:InAs-sensing medium,by taking advantage of the hybrid surface plasmon phonon polariton(SPPhP)in mid-IR regime.Here,heavily Si-doped InAs(Si:InAs)and SiC excite the SPP and surface phonon polariton(SPhP),and the hybrid SPPhP is realized in this system.More importantly,the designed PSHE sensor based on this SPPhP mechanism achieves the multi-stage RI measurements from 1.00025-1.00225 to 1.70025-1.70225,and the maximal intensity sensitivity and angle sensitivity can be up to 9.4×10^(4)μm/RIU and245°/RIU,respectively.These findings provide a new pathway for the enhancement of PSHE in mid-IR regime,and offer new opportunities to develop highly sensitive RI sensors in multi-scenario applications,such as harmful gas monitoring and biosensing.展开更多
The Electrical Power System(EPS)is one of the spacecraft’s key subsystems,and its operational status directly affects the lifespan and performance of the entire spacecraft.The corresponding fault diagnosis has always...The Electrical Power System(EPS)is one of the spacecraft’s key subsystems,and its operational status directly affects the lifespan and performance of the entire spacecraft.The corresponding fault diagnosis has always been the discussion focus to ensure spacecraft reliability.In this paper,a few-shot unsupervised fault diagnosis method based on the improved Newman community division algorithm is proposed,to approach the scarcity of fault data samples and the inconspicuous characteristics of abnormal data.Firstly,aiming to capture the overall relevance of the fault dataset,a complex network model is built by adopting the K-Dynamic time warping distance Adjacent Nodes(KDAN)method.Based on the complex network model,the Newman community divisions algorithm is improved by using the Quantum-behaved Particle Swarm Optimization(QPSO).Subsequently,in order to evaluate the feasibility of the proposed method,experimental validation was conducted using an open-source dataset.The results indicate that the average accuracy can reach 96.43% for fault data diagnosis,and an F1_score of 97.76%with only 17.65%of the dataset used for training.The proposed method can accurately classify abnormal data by identifying the community structure in the data network,significantly improve the efficiency of the community divisions algorithm and reduce its complexity,and provide a new solution for fault diagnosis in large-scale complex systems.展开更多
In the context of the coordinated pursuit of"carbon peak and neutrality"objectives,alongside the strategy to establish a robust agricultural nation,the economic and social development of rural areas is under...In the context of the coordinated pursuit of"carbon peak and neutrality"objectives,alongside the strategy to establish a robust agricultural nation,the economic and social development of rural areas is undergoing a profound paradigm shift.The traditional rural division of labor pattern,which depends on tangible factors such as land,labor,and capital,has increasingly encountered developmental challenges characterized by diminishing marginal returns and a detrimental cycle of internal competition.The new quality productive force,centered on data,algorithms,green technologies,bioengineering,and clean energy,offers a potential pathway for the rural division of labor system to overcome the"low-level equilibrium".This force is characterized by attributes such as non-exclusivity,replicability,network collaboration,and ecological compatibility.This paper develops a three-dimensional collaborative analytical framework encompassing"technology,institution,and culture".It systematically elucidates the internal logic by which new quality productive forces drive the transformation of the rural division of labor from"quantitative factor matching"to"qualitative structural reorganization"through three principal mechanisms:technology embedding,institutional reconstruction,and cultural coupling.Furthermore,the study proposes corresponding policy recommendations,thereby offering theoretical insights to support the modernization of China s agriculture and rural areas,as well as the development of a strong agricultural country.展开更多
The application of machine learning for pyrite discrimination establishes a robust foundation for constructing the ore-forming history of multi-stage deposits;however,published models face challenges related to limite...The application of machine learning for pyrite discrimination establishes a robust foundation for constructing the ore-forming history of multi-stage deposits;however,published models face challenges related to limited,imbalanced datasets and oversampling.In this study,the dataset was expanded to approximately 500 samples for each type,including 508 sedimentary,573 orogenic gold,548 sedimentary exhalative(SEDEX)deposits,and 364 volcanogenic massive sulfides(VMS)pyrites,utilizing random forest(RF)and support vector machine(SVM)methodologies to enhance the reliability of the classifier models.The RF classifier achieved an overall accuracy of 99.8%,and the SVM classifier attained an overall accuracy of 100%.The model was evaluated by a five-fold cross-validation approach with 93.8%accuracy for the RF and 94.9%for the SVM classifier.These results demonstrate the strong feasibility of pyrite classification,supported by a relatively large,balanced dataset and high accuracy rates.The classifier was employed to reveal the genesis of the controversial Keketale Pb-Zn deposit in NW China,which has been inconclusive among SEDEX,VMS,or a SEDEX-VMS transition.Petrographic investigations indicated that the deposit comprises early fine-grained layered pyrite(Py1)and late recrystallized pyrite(Py2).The majority voting classified Py1 as the VMS type,with an accuracy of RF and SVM being 72.2%and 75%,respectively,and confirmed Py2 as an orogenic type with 74.3% and 77.1%accuracy,respectively.The new findings indicated that the Keketale deposit originated from a submarine VMS mineralization system,followed by late orogenic-type overprinting of metamorphism and deformation,which is consistent with the geological and geochemical observations.This study further emphasizes the advantages of Machine learning(ML)methods in accurately and directly discriminating the deposit types and reconstructing the formation history of multi-stage deposits.展开更多
Fast and accurate transient stability analysis is crucial to power system operation.With high penetration level of wind power resources,practical dynamic security region(PDSR)with hyper plane expression has outstandin...Fast and accurate transient stability analysis is crucial to power system operation.With high penetration level of wind power resources,practical dynamic security region(PDSR)with hyper plane expression has outstanding advantages in situational awareness and series of optimization problems.The precondition of obtaining accurate PDSR boundary is to locate sufficient points around the boundary(critical points).Therefore,this paper proposes a space division and Wasserstein generative adversarial network with gra-dient penalty(WGAN-GP)based fast generation method of PDSR boundary.First,the typical differential topological characterizations of dynamic security region(DSR)provide strong theoretical foundation that the interior of DSR is hole-free and the boundaries of DSR are tight and knot-free.Then,the space division method is proposed to calculate critical operation area where the PDSR boundary is located,tremen-dously compressing the search space to locate critical points and improving the confidence level of boundary fitting result.Furthermore,the WGAN-GP model is utilized to fast obtain large number of criti-cal points based on learning the data distribution of the small training set aforementioned.Finally,the PDSR boundary with hyperplanes is fitted by the least square method.The case study is tested on the Institute of Electrical and Electronics Engineers(IEEE)39-bus system and the results verify the accuracy and efficiency of the proposed method.展开更多
The high proportion of uncertain distributed power sources and the access to large-scale random electric vehicle(EV)charging resources further aggravate the voltage fluctuation of the distribution network,and the exis...The high proportion of uncertain distributed power sources and the access to large-scale random electric vehicle(EV)charging resources further aggravate the voltage fluctuation of the distribution network,and the existing research has not deeply explored the EV active-reactive synergistic regulating characteristics,and failed to realize themulti-timescale synergistic control with other regulatingmeans,For this reason,this paper proposes amultilevel linkage coordinated optimization strategy to reduce the voltage deviation of the distribution network.Firstly,a capacitor bank reactive power compensation voltage control model and a distributed photovoltaic(PV)activereactive power regulationmodel are established.Additionally,an external characteristicmodel of EVactive-reactive power regulation is developed considering the four-quadrant operational characteristics of the EVcharger.Amultiobjective optimization model of the distribution network is then constructed considering the time-series coupling constraints of multiple types of voltage regulators.A multi-timescale control strategy is proposed by considering the impact of voltage regulators on active-reactive EV energy consumption and PV energy consumption.Then,a four-stage voltage control optimization strategy is proposed for various types of voltage regulators with multiple time scales.Themulti-objective optimization is solved with the improvedDrosophila algorithmto realize the power fluctuation control of the distribution network and themulti-stage voltage control optimization.Simulation results validate that the proposed voltage control optimization strategy achieves the coordinated control of decentralized voltage control resources in the distribution network.It effectively reduces the voltage deviation of the distribution network while ensuring the energy demand of EV users and enhancing the stability and economic efficiency of the distribution network.展开更多
Although previous researchers have attempted to decipher ore genesis and mineralization in the Erdaokan Ag-Pb-Zn deposit,some uncertainties regarding the mineralization process and evolution of both ore-forming fluids...Although previous researchers have attempted to decipher ore genesis and mineralization in the Erdaokan Ag-Pb-Zn deposit,some uncertainties regarding the mineralization process and evolution of both ore-forming fluids and magnetite types still need to be addressed.In this study,we obtained new EPMA,LA-ICP-MS,and in situ Fe isotope data from magnetite from the Erdaokan deposit,in order to better understand the mineralization mechanism and evolution of both magnetite and the ore-forming fluids.Our results identified seven types of magnetite at Erdaokan:disseminated magnetite(Mag1),coarse-grained magnetite(Mag2a),radial magnetite(Mag2b),fragmented fine-grained magnetite(Mag2c),vermicular gel magnetite(Mag3a1 and Mag3a2),colloidal magnetite(Mag3b)and dark gray magnetite(Mag4).All of the magnetite types were hydrothermal in origin and generally low in Ti(<400 ppm)and Ni(<800 ppm),while being enriched in light Fe isotopes(δ^(56)Fe ranging from−1.54‰to−0.06‰).However,they exhibit different geochemical signatures and are thus classified into high-manganese magnetite(Mag1,MnO>5 wt%),low-silicon magnetite(Mag2a-c,SiO_(2)<1 wt%),high-silicon magnetite(Mag3a-b,SiO_(2)from 1 to 7 wt%)and high-silicon-manganese magnetite(Mag4,SiO_(2)>1 wt%,MnO>0.2 wt%),each being formed within distinct hydrothermal environments.Based on mineralogy,elemental geochemistry,Fe isotopes,temperature trends,TMg-mag and(Ti+V)vs.(Al+Mn)diagrams,we propose that the Erdaokan Ag-Pb-Zn deposit underwent multi-stage mineralization,which can be broken down into four stages and nine sub-stages.Mag1,Mag2a-c,Mag3a-b and Mag4 were formed during the first sub-stage of each of the four stages,respectively.Additionally,fluid mixing,cooling and depressurization boiling were identified as the main mechanisms for mineral precipitation.The enrichment of Ag was significantly enhanced by the superposition of multi-stage ore-forming hydrothermal fluids in the Erdaokan Ag-Pb-Zn deposit.展开更多
Using data from the 2022 China Family Panel Studies(CFPS),this study selects 11,375 dual-spouse households as the research sample and constructs a comprehensive housework division index via the entropy weight method.T...Using data from the 2022 China Family Panel Studies(CFPS),this study selects 11,375 dual-spouse households as the research sample and constructs a comprehensive housework division index via the entropy weight method.The index integrates four dimensions:participation subject,time allocation,content type,and fairness perception,aiming to explore the fairness level of housework division and group differences in Chinese households.The results show that the overall fairness of housework division in Chinese households is relatively low:the mean value of the index(after 10,000-fold linear expansion)is 0.0632,showing a significant right-skewed distribution,with most households concentrated in the"low-fairness"range and only a few achieving relatively balanced division.Significant group differences exist:rural households have a slightly higher housework division index(0.0659)than urban households(0.0608);male respondents have a higher index(0.0660)than female respondents(0.0603);and the high-education group has a significantly lower index(0.0501)than the low-education group(0.0653).The fairness of housework division is jointly influenced by structural factors and perceptual factors,with an obvious"concept-action gap":74.02%of respondents perceive housework division as"fair",but the low index level indicates this perception mostly stems from normative adaptation rather than objective balance.This study provides empirical evidence for optimizing family labor allocation and promoting gender equality.展开更多
This paper presents a new criterion for determining the unloading points quantitatively and consistently in a multi-stage triaxial test.The radial strain gradient(RSG)is first introduced as an arc tangent function of ...This paper presents a new criterion for determining the unloading points quantitatively and consistently in a multi-stage triaxial test.The radial strain gradient(RSG)is first introduced as an arc tangent function of the rate of change of radial strain to time.RSG is observed to correlate closely with the stress state of a compressed sample,and reaches a horizontal asymptote as approaching failure.For a given rock type,RSG value at peak stress is almost the same,irrespective of the porosity and permeability.These findings lead to the development of RSG criterion:Unloading points can be precisely determined at the time when RSG reaches a pre-determined value that is a little smaller than or equal to the RSG at peak stress.The RSG criterion is validated against other criteria and the single-stage triaxial test on various types of rocks.Failure envelopes from the RSG criterion match well with those from single-stage tests.A practical procedure is recommended to use the RSG criterion:an unconfined compression or single-stage test is first conducted to determine the RSG at peak stress for one sample,the unloading point is then selected to be a value close to the RSG at peak stress,and the multi-stage test is finally performed on another sample using the pre-selected RSG unloading criterion.Generally,the RSG criterion is applicable for any type of rocks,especially brittle rocks,where other criteria are not suitable.Further,it can be practically implemented on the most available rock mechanical testing instruments.展开更多
A new hang-off system has been proposed to improve the security of risers in hang-off modes during typhoons.However,efficient anti-typhoon evacuation strategies have not been investigated.Optimiza-tion model and metho...A new hang-off system has been proposed to improve the security of risers in hang-off modes during typhoons.However,efficient anti-typhoon evacuation strategies have not been investigated.Optimiza-tion model and method for the anti-typhoon evacuation strategies should be researched.Therefore,multi-objective functions are proposed based on operation time,evacuation speed stability,and steering stability.An evacuation path model and a dynamic model of risers with the new hang-off system are developed for design variables and constraints.A multi-objective optimization model with high-dimensional variables and complex constraints is established.Finally,a three-stage optimization method based on genetic algorithm,least square method,and the penalty function method is proposed to solve the multi-objective optimization model.Optimization results show that the operation time can be reduced through operation parameter optimization,especially evacuation heading optimization.The optimal anti-typhoon strategy is evacuation with all risers suspended along a variable path when the direction angle is large,while evacuation with all risers suspended along a straight path at another di-rection angle.Besides,the influencing factors on anti-typhoon evacuation strategies indicate that the proposed optimization model and method have strong applicability to working conditions and remarkable optimization effects.展开更多
Cell division is a fundamental biological process in which a parent cell divides into two daughter cells.The cell cortex,a thin layer primarily composed of actin filaments and myosin motors beneath the plasma membrane...Cell division is a fundamental biological process in which a parent cell divides into two daughter cells.The cell cortex,a thin layer primarily composed of actin filaments and myosin motors beneath the plasma membrane,plays a critical role in ensuring proper cell division.In this study,we apply a hydrodynamic model to describe the actin cortex as an active nematic surface,incorporating orientational order arising from actin filament alignment and anisotropic active stress produced by myosin motors.By analyzing the linearized dynamics,we investigate how shape,flow,and stress regulators evolve over time when the surface deviates slightly from a sphere.Our findings reveal that the active alignment of actin filaments,often overlooked in previous studies,is crucial for successful division.Furthermore,we demonstrate that a cortical chiral flow naturally emerges as a consequence of this active alignment.Overall,our results provide a mechanistic explanation for key phenomena observed during cell division,offering new insights into the role of active stress and filament alignment in cortical dynamics.展开更多
Acute respiratory distress syndrome(ARDS)is a common respiratory emergency,but current clinical treatment remains at the level of symptomatic support and there is a lack of effective targeted treatment measures.Our pr...Acute respiratory distress syndrome(ARDS)is a common respiratory emergency,but current clinical treatment remains at the level of symptomatic support and there is a lack of effective targeted treatment measures.Our previous study confirmed that inhalation of hydrogen gas can reduce the acute lung injury of ARDS,but the application of hydrogen has flammable and explosive safety concerns.Drinking hydrogen-rich liquid or inhaling hydrogen gas has been shown to play an important role in scavenging reactive oxygen species and maintaining mitochondrial quality control balance,thus improving ARDS in patients and animal models.Coral calcium hydrogenation(CCH)is a new solid molecular hydrogen carrier prepared from coral calcium(CC).Whether and how CCH affects acute lung injury in ARDS remains unstudied.In this study,we observed the therapeutic effect of CCH on lipopolysaccharide(LPS)induced acute lung injury in ARDS mice.The survival rate of mice treated with CCH and hydrogen inhalation was found to be comparable,demonstrating a significant improvement compared to the untreated ARDS model group.CCH treatment significantly reduced pulmonary hemorrhage and edema,and improved pulmonary function and local microcirculation in ARDS mice.CCH promoted mitochondrial peripheral division in the early course of ARDS by activating mitochondrial thioredoxin 2(Trx2),improved lung mitochondrial dysfunction induced by LPS,and reduced oxidative stress damage.The results indicate that CCH is a highly efficient hydrogen-rich agent that can attenuate acute lung injury of ARDS by improving the mitochondrial function through Trx2 activation.展开更多
Nano zero-valent iron(nZVI)is a promising phosphate adsorbent for advanced phosphate removal.However,the rapid passivation of nZVI and the low activity of adsorption sites seriously limit its phosphate removal perform...Nano zero-valent iron(nZVI)is a promising phosphate adsorbent for advanced phosphate removal.However,the rapid passivation of nZVI and the low activity of adsorption sites seriously limit its phosphate removal performance,accounting for its inapplicability to meet the emission criteria of 0.1 mg P/L phosphate.In this study,we report that the oxalate modification can inhibit the passivation of nZVI and alter the multi-stage phosphate adsorption mechanism by changing the adsorption sites.As expected,the stronger antipassivation ability of oxalate modified nZVI(OX-nZVI)strongly favored its phosphate adsorption.Interestingly,the oxalate modification endowed the surface Fe(III)sites with the lowest chemisorption energy and the fastest phosphate adsorption ability than the other adsorption sites,by in situ forming a Fe(III)-phosphate-oxalate ternary complex,therefore enabling an advanced phosphate removal process.At an initial phosphate concentration of 1.00 mg P/L,pH of 6.0 and a dosage of 0.3 g/L of adsorbents,OX-nZVI exhibited faster phosphate removal rate(0.11 g/mg/min)and lower residual phosphate level(0.02 mg P/L)than nZVI(0.055 g/mg/min and 0.19 mg P/L).This study sheds light on the importance of site manipulation in the development of high-performance adsorbents,and offers a facile surface modification strategy to prepare superior iron-basedmaterials for advanced phosphate removal.展开更多
From the concept of the "Production-Living-Ecology" Spaces, this paper sorts out the theoretical basis, division principles, and division methods of the "Production-Living-Ecology" Spaces, and then...From the concept of the "Production-Living-Ecology" Spaces, this paper sorts out the theoretical basis, division principles, and division methods of the "Production-Living-Ecology" Spaces, and then proposes future prospects for them. The integration of theory and practice of "Production-Living-Ecology" Spaces is currently in a stage of in-depth exploration and practical application. Future research should fully recognize the importance and necessity of theoretical research on "Production-Living-Ecology" Spaces under the new situation, and consolidate the theoretical foundation for research on the development and protection of territorial space in the new era.展开更多
Time division multiplexing(TDM)architecture is an important approach to creating sensor arrays for massive scale monitoring.But it is paradoxical for the TDM interferometric sensor array to keep a short delay fiber fo...Time division multiplexing(TDM)architecture is an important approach to creating sensor arrays for massive scale monitoring.But it is paradoxical for the TDM interferometric sensor array to keep a short delay fiber for high sensing resolution and meanwhile use low sampling rate for practical applications.In this paper,a phase matching sampling(PMS)paradigm is proposed to address the above contradiction.By matching the phase of the sampling clock with the delay fiber length,combining with multiple-pulses sampling strategy,the proposed PMS method can avoid collecting the redundant information,facilitating the decreasing of sampling rate as well as delay fiber length of the TDM sensing system.The proof-of-concept experiments on an 8-channel TDM interferometric system demonstrate that when the sampling rate is fixed at 20 MS/s,by applying the PMS algorithm,the delay fiber length can be shortened from 100 m to 1 m,compared with applying the conventional sampling method.It reduced the phase noise of the system by a factor of 10 at 1 mHz and by a factor of 50 at 1 Hz.The PMS algorithm for greatly reducing the sampling rate is expected to fuel the TDM interferometric sensor arrays for many applications.展开更多
Large-capacity data transmission is increasingly required to meet the growing demands of big data and artificial intelligence applications.Wavelength-division multiplexing(WDM)technology is a reliable method of increa...Large-capacity data transmission is increasingly required to meet the growing demands of big data and artificial intelligence applications.Wavelength-division multiplexing(WDM)technology is a reliable method of increasing link capacity by enabling multiple wavelength signals to be transmitted in a single channel.Here,for the first time,a large-capacity transmitter on thin-film lithium tantalate-on-insulator(LTOI)is demonstrated by monolithically integrating an 8-channel WDM and Mach–Zehnder interferometer(MZI)electro-optic modulators(EOMs).The integrated 8-channel WDM,comprised of 8 cascaded waveguide Bragg grating optical filters,realizes channel spacing of 16.8 nm,1-dB bandwidth of 15.4 nm,and thermal sensitivity of 10 pm/oC.The MZI EOMs show low direct current drift and 3-dB bandwidth beyond 67 GHz.Finally,the WDM transmitter achieves a data rate of 100 Gbps OOK and 200 Gbps PAM4 for a single channel,indicating the demonstrated total capacity of 1.6 Tbps.Therefore,the demonstrated large-capacity WDM transmitter will find many applications,such as artificial intelligence and data centers.展开更多
WITHDRAWAL:Zhang,J.J.,Guo,Y.Q.,Qin,Z.Y.,Wei,C.T.,Hu,Q.H.,Vandeginste,V.,Miao,H.Y.,Yao,P.,and Zhang,P.F.,“Predicting Irreducible Water Saturation of Unconventional Reservoirs by Using NMR T2 Spectra:Methods of Morphol...WITHDRAWAL:Zhang,J.J.,Guo,Y.Q.,Qin,Z.Y.,Wei,C.T.,Hu,Q.H.,Vandeginste,V.,Miao,H.Y.,Yao,P.,and Zhang,P.F.,“Predicting Irreducible Water Saturation of Unconventional Reservoirs by Using NMR T2 Spectra:Methods of Morphological Division and Fractal Models”,Acta Geologica Sinica-English Edition(Accepted Article):https://doi.org/10.1111/1755-6724.15094.展开更多
The Asia-Pacific region is the most dynamic part of the global economy.After over 50 years of continuously expanding trade,investment and industrial cooperation,the region has formed a highly-tied multi-level labor di...The Asia-Pacific region is the most dynamic part of the global economy.After over 50 years of continuously expanding trade,investment and industrial cooperation,the region has formed a highly-tied multi-level labor division system covering vertical integration and horizontal complementarity of industrial chains.From the V-shaped development model in the twentieth century to the East Asian production network in the twenty-first century,the intra-industry and intra-product division of labor in the Asia-Pacific region has been ever deepening.However,due to the region’s high dependence on the U.S.market,the division of labor model in the Asia-Pacific suffers structural problems and is relatively fragile.Under the shock of Trump 1.0,countries in the Asia-Pacific region were forced to make adaptive adjustments,causing short-term turmoil in the regional economic order.Trump’s strong return in 2025,driven by the“America First”principle,brought forth a series of policies with strong unilateralism,isolationism and protectionism tendencies within just a few months。展开更多
The effectiveness of horizontal well multi-stage and multi-cluster fracturing in the fractured soft coal seam roof for coalbed methane(CBM) extraction has been demonstrated.This study focuses on the geological charact...The effectiveness of horizontal well multi-stage and multi-cluster fracturing in the fractured soft coal seam roof for coalbed methane(CBM) extraction has been demonstrated.This study focuses on the geological characteristics of the No.5 and No.11 coal seams in the Hancheng Block,Ordos Basin,China.A multi-functional,variable-size rock sample mold capable of securing the wellbore was developed to simulate layered formations comprising strata of varying lithology and thicknesses.A novel segmented fracturing simulation method based on an expandable pipe plugging technique is proposed.Large-scale true triaxial experiments were conducted to investigate the effects of horizontal wellbore location,perforation strategy,roof lithology,and vertical stress difference on fracture propagation,hydraulic energy variation,and the stimulated reservoir volume in horizontal wells targeting the soft coal seam roof.The results indicate that bilateral downward perforation with a phase angle of 120° optimizes hydraulic energy conservation,reduces operational costs,enhances fracture formation,and prevents fracturing failure caused by coal powder generation and migration.This perforation mode is thus considered optimal for coal seam roof fracturing.When the roof consists of sandstone,each perforation cluster tends to initiate a single dominant fracture with a regular geometry.In contrast,hydraulic fractures formed in mudstone roofs display diverse morphology.Due to its high strength,the sandstone roof requires significantly higher pressure for crack initiation and propagation,whereas the mudstone roof,with its strong water sensitivity,exhibits lower fracturing pressures.To mitigate inter-cluster interference,cluster spacing in mudstone roofs should be greater than that in sandstone roofs.Horizontal wellbore placement critically influences fracturing effectiveness.For indirect fracturing in sandstone roofs,an optimal position is 25 mm away from the lithological interface.In contrast,the optimal location for indirect fracturing in mudstone roofs is directly at the lithological interface with the coal seam.Higher vertical stress coefficients lead to increased fractu ring pressures and promote vertical,layer-penetrating fractures.A coefficient of 0.5 is identified as optimal for achieving effective indirect fracturing.This study provides valuable insights for the design and optimization of staged fracturing in horizontal wells targeting crushed soft coal seam roofs.展开更多
BACKGROUND Hepatocellular carcinoma(HCC)ranks among the most prevalent and deadly malignancies,characterized by a high recurrence rate.Regulator of chromosome condensation 1(RCC1)serves as a principal guanine nucleoti...BACKGROUND Hepatocellular carcinoma(HCC)ranks among the most prevalent and deadly malignancies,characterized by a high recurrence rate.Regulator of chromosome condensation 1(RCC1)serves as a principal guanine nucleotide exchange factor for ras-related nuclear protein guanosine triphosphatase(GTPase)and is implicated in various cancers.However,the role of RCC1 in HCC remains unex-plored.AIM To elucidate the functional significance and molecular mechanisms of RCC1 in HCC.METHODS Bioinformatics were to examine the expression levels of RCC1 in HCC and to assess its impact on the prognosis of this malignancy.The cell counting kit-8 assay and flow cytometry were utilized to evaluate the cell viability and cell cycle of HCC cells.Furthermore,quantitative reverse transcription and immunoblotting were to investigate the influence of RCC1 on cyclin associated proteins.RESULTS Bioinformatics analysis revealed that RCC1 was highly expressed in HCC and correlated with poor prognosis in HCC patients.Functional studies showed that RCC1 overexpression promoted the malignant phenotype of HCC cells,especially the proliferation of HCC cells,whereas RCC1 knockdown had the opposite effect.Mechanistically,we identied cell division cycle-associated(CDCA)8 as a downstream target of RCC1 in HCC.RCC1 overexpression markedly increased CDCA8 levels,consequently enhancing cell proliferation and survival in HCC cells.Additionally,we discovered that RCC1 contributed to the development and progression of HCC by activating the phosphoinositide 3-kinase/protein kinase B/cyclin-dependent kinase inhibitor 1a pathway through CDCA8.CONCLUSION Our study provides profound insights into the pivotal role of RCC1 in HCC and its potential as a therapeutic target.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant No.12175107)the Qing Lan Project of Jiangsu Province+2 种基金the Hua Li Talents Program of Nanjing University of PostsTelecommunications,Natural Science Foundation of Nanjing Vocational University of Industry Technology(Grant No.YK22-02-08)the Fund from the Research Center of Industrial Perception and Intelligent Manufacturing Equipment Engineering of Jiangsu Province,China(Grant No.ZK21-05-09)。
文摘Surface polaritons,as surface electromagnetic waves propagating along the surface of a medium,have played a crucial role in enhancing photonic spin Hall effect(PSHE)and developing highly sensitive refractive index(RI)sensors.Among them,the traditional surface plasmon polariton(SPP)based on noble metals limits its application beyond the near-infrared(IR)regime due to the large negative permittivity and optical losses.In this contribution,we theoretically proposed a highly sensitive PSHE sensor with the structure of Ge prism-SiC-Si:InAs-sensing medium,by taking advantage of the hybrid surface plasmon phonon polariton(SPPhP)in mid-IR regime.Here,heavily Si-doped InAs(Si:InAs)and SiC excite the SPP and surface phonon polariton(SPhP),and the hybrid SPPhP is realized in this system.More importantly,the designed PSHE sensor based on this SPPhP mechanism achieves the multi-stage RI measurements from 1.00025-1.00225 to 1.70025-1.70225,and the maximal intensity sensitivity and angle sensitivity can be up to 9.4×10^(4)μm/RIU and245°/RIU,respectively.These findings provide a new pathway for the enhancement of PSHE in mid-IR regime,and offer new opportunities to develop highly sensitive RI sensors in multi-scenario applications,such as harmful gas monitoring and biosensing.
基金supported in part by the Natural Science Foundation of Shanghai,China(No.23ZR1432400)the Shanghai Pilot Program for Basic Research-Chinese Academy of Science(No.JCYJ-SHFY-2022-015).
文摘The Electrical Power System(EPS)is one of the spacecraft’s key subsystems,and its operational status directly affects the lifespan and performance of the entire spacecraft.The corresponding fault diagnosis has always been the discussion focus to ensure spacecraft reliability.In this paper,a few-shot unsupervised fault diagnosis method based on the improved Newman community division algorithm is proposed,to approach the scarcity of fault data samples and the inconspicuous characteristics of abnormal data.Firstly,aiming to capture the overall relevance of the fault dataset,a complex network model is built by adopting the K-Dynamic time warping distance Adjacent Nodes(KDAN)method.Based on the complex network model,the Newman community divisions algorithm is improved by using the Quantum-behaved Particle Swarm Optimization(QPSO).Subsequently,in order to evaluate the feasibility of the proposed method,experimental validation was conducted using an open-source dataset.The results indicate that the average accuracy can reach 96.43% for fault data diagnosis,and an F1_score of 97.76%with only 17.65%of the dataset used for training.The proposed method can accurately classify abnormal data by identifying the community structure in the data network,significantly improve the efficiency of the community divisions algorithm and reduce its complexity,and provide a new solution for fault diagnosis in large-scale complex systems.
基金Supported by Key Project of Jiangsu Education Science Planning"Research on the Structural Adjustment of Higher Education in Jiangsu in the Context of High-Quality Economic Development"(B/2021/01/67).
文摘In the context of the coordinated pursuit of"carbon peak and neutrality"objectives,alongside the strategy to establish a robust agricultural nation,the economic and social development of rural areas is undergoing a profound paradigm shift.The traditional rural division of labor pattern,which depends on tangible factors such as land,labor,and capital,has increasingly encountered developmental challenges characterized by diminishing marginal returns and a detrimental cycle of internal competition.The new quality productive force,centered on data,algorithms,green technologies,bioengineering,and clean energy,offers a potential pathway for the rural division of labor system to overcome the"low-level equilibrium".This force is characterized by attributes such as non-exclusivity,replicability,network collaboration,and ecological compatibility.This paper develops a three-dimensional collaborative analytical framework encompassing"technology,institution,and culture".It systematically elucidates the internal logic by which new quality productive forces drive the transformation of the rural division of labor from"quantitative factor matching"to"qualitative structural reorganization"through three principal mechanisms:technology embedding,institutional reconstruction,and cultural coupling.Furthermore,the study proposes corresponding policy recommendations,thereby offering theoretical insights to support the modernization of China s agriculture and rural areas,as well as the development of a strong agricultural country.
基金the National Key Research and Development Program of China(2021YFC2900300)the Natural Science Foundation of Guangdong Province(2024A1515030216)+2 种基金MOST Special Fund from State Key Laboratory of Geological Processes and Mineral Resources,China University of Geosciences(GPMR202437)the Guangdong Province Introduced of Innovative R&D Team(2021ZT09H399)the Third Xinjiang Scientific Expedition Program(2022xjkk1301).
文摘The application of machine learning for pyrite discrimination establishes a robust foundation for constructing the ore-forming history of multi-stage deposits;however,published models face challenges related to limited,imbalanced datasets and oversampling.In this study,the dataset was expanded to approximately 500 samples for each type,including 508 sedimentary,573 orogenic gold,548 sedimentary exhalative(SEDEX)deposits,and 364 volcanogenic massive sulfides(VMS)pyrites,utilizing random forest(RF)and support vector machine(SVM)methodologies to enhance the reliability of the classifier models.The RF classifier achieved an overall accuracy of 99.8%,and the SVM classifier attained an overall accuracy of 100%.The model was evaluated by a five-fold cross-validation approach with 93.8%accuracy for the RF and 94.9%for the SVM classifier.These results demonstrate the strong feasibility of pyrite classification,supported by a relatively large,balanced dataset and high accuracy rates.The classifier was employed to reveal the genesis of the controversial Keketale Pb-Zn deposit in NW China,which has been inconclusive among SEDEX,VMS,or a SEDEX-VMS transition.Petrographic investigations indicated that the deposit comprises early fine-grained layered pyrite(Py1)and late recrystallized pyrite(Py2).The majority voting classified Py1 as the VMS type,with an accuracy of RF and SVM being 72.2%and 75%,respectively,and confirmed Py2 as an orogenic type with 74.3% and 77.1%accuracy,respectively.The new findings indicated that the Keketale deposit originated from a submarine VMS mineralization system,followed by late orogenic-type overprinting of metamorphism and deformation,which is consistent with the geological and geochemical observations.This study further emphasizes the advantages of Machine learning(ML)methods in accurately and directly discriminating the deposit types and reconstructing the formation history of multi-stage deposits.
基金funded in part by the National Key Research and Development Program of China(2020YFB0905900)in part by Science and Technology Project of State Grid Corporation of China(SGCC)The Key Technologies for Electric Internet of Things(SGTJDK00DWJS2100223).
文摘Fast and accurate transient stability analysis is crucial to power system operation.With high penetration level of wind power resources,practical dynamic security region(PDSR)with hyper plane expression has outstanding advantages in situational awareness and series of optimization problems.The precondition of obtaining accurate PDSR boundary is to locate sufficient points around the boundary(critical points).Therefore,this paper proposes a space division and Wasserstein generative adversarial network with gra-dient penalty(WGAN-GP)based fast generation method of PDSR boundary.First,the typical differential topological characterizations of dynamic security region(DSR)provide strong theoretical foundation that the interior of DSR is hole-free and the boundaries of DSR are tight and knot-free.Then,the space division method is proposed to calculate critical operation area where the PDSR boundary is located,tremen-dously compressing the search space to locate critical points and improving the confidence level of boundary fitting result.Furthermore,the WGAN-GP model is utilized to fast obtain large number of criti-cal points based on learning the data distribution of the small training set aforementioned.Finally,the PDSR boundary with hyperplanes is fitted by the least square method.The case study is tested on the Institute of Electrical and Electronics Engineers(IEEE)39-bus system and the results verify the accuracy and efficiency of the proposed method.
基金funded by the State Grid Corporation Science and Technology Project(5108-202218280A-2-391-XG).
文摘The high proportion of uncertain distributed power sources and the access to large-scale random electric vehicle(EV)charging resources further aggravate the voltage fluctuation of the distribution network,and the existing research has not deeply explored the EV active-reactive synergistic regulating characteristics,and failed to realize themulti-timescale synergistic control with other regulatingmeans,For this reason,this paper proposes amultilevel linkage coordinated optimization strategy to reduce the voltage deviation of the distribution network.Firstly,a capacitor bank reactive power compensation voltage control model and a distributed photovoltaic(PV)activereactive power regulationmodel are established.Additionally,an external characteristicmodel of EVactive-reactive power regulation is developed considering the four-quadrant operational characteristics of the EVcharger.Amultiobjective optimization model of the distribution network is then constructed considering the time-series coupling constraints of multiple types of voltage regulators.A multi-timescale control strategy is proposed by considering the impact of voltage regulators on active-reactive EV energy consumption and PV energy consumption.Then,a four-stage voltage control optimization strategy is proposed for various types of voltage regulators with multiple time scales.Themulti-objective optimization is solved with the improvedDrosophila algorithmto realize the power fluctuation control of the distribution network and themulti-stage voltage control optimization.Simulation results validate that the proposed voltage control optimization strategy achieves the coordinated control of decentralized voltage control resources in the distribution network.It effectively reduces the voltage deviation of the distribution network while ensuring the energy demand of EV users and enhancing the stability and economic efficiency of the distribution network.
基金financially supported by the Heilongjiang Provincial Key R&D Program Project(No.GA21A204)Heilongjiang Provincial Natural Science Foundation of China(No.LH2022D031)the Research Project of Heilongjiang Province Bureau of Geology and Mineral Resources(No.HKY202302).
文摘Although previous researchers have attempted to decipher ore genesis and mineralization in the Erdaokan Ag-Pb-Zn deposit,some uncertainties regarding the mineralization process and evolution of both ore-forming fluids and magnetite types still need to be addressed.In this study,we obtained new EPMA,LA-ICP-MS,and in situ Fe isotope data from magnetite from the Erdaokan deposit,in order to better understand the mineralization mechanism and evolution of both magnetite and the ore-forming fluids.Our results identified seven types of magnetite at Erdaokan:disseminated magnetite(Mag1),coarse-grained magnetite(Mag2a),radial magnetite(Mag2b),fragmented fine-grained magnetite(Mag2c),vermicular gel magnetite(Mag3a1 and Mag3a2),colloidal magnetite(Mag3b)and dark gray magnetite(Mag4).All of the magnetite types were hydrothermal in origin and generally low in Ti(<400 ppm)and Ni(<800 ppm),while being enriched in light Fe isotopes(δ^(56)Fe ranging from−1.54‰to−0.06‰).However,they exhibit different geochemical signatures and are thus classified into high-manganese magnetite(Mag1,MnO>5 wt%),low-silicon magnetite(Mag2a-c,SiO_(2)<1 wt%),high-silicon magnetite(Mag3a-b,SiO_(2)from 1 to 7 wt%)and high-silicon-manganese magnetite(Mag4,SiO_(2)>1 wt%,MnO>0.2 wt%),each being formed within distinct hydrothermal environments.Based on mineralogy,elemental geochemistry,Fe isotopes,temperature trends,TMg-mag and(Ti+V)vs.(Al+Mn)diagrams,we propose that the Erdaokan Ag-Pb-Zn deposit underwent multi-stage mineralization,which can be broken down into four stages and nine sub-stages.Mag1,Mag2a-c,Mag3a-b and Mag4 were formed during the first sub-stage of each of the four stages,respectively.Additionally,fluid mixing,cooling and depressurization boiling were identified as the main mechanisms for mineral precipitation.The enrichment of Ag was significantly enhanced by the superposition of multi-stage ore-forming hydrothermal fluids in the Erdaokan Ag-Pb-Zn deposit.
文摘Using data from the 2022 China Family Panel Studies(CFPS),this study selects 11,375 dual-spouse households as the research sample and constructs a comprehensive housework division index via the entropy weight method.The index integrates four dimensions:participation subject,time allocation,content type,and fairness perception,aiming to explore the fairness level of housework division and group differences in Chinese households.The results show that the overall fairness of housework division in Chinese households is relatively low:the mean value of the index(after 10,000-fold linear expansion)is 0.0632,showing a significant right-skewed distribution,with most households concentrated in the"low-fairness"range and only a few achieving relatively balanced division.Significant group differences exist:rural households have a slightly higher housework division index(0.0659)than urban households(0.0608);male respondents have a higher index(0.0660)than female respondents(0.0603);and the high-education group has a significantly lower index(0.0501)than the low-education group(0.0653).The fairness of housework division is jointly influenced by structural factors and perceptual factors,with an obvious"concept-action gap":74.02%of respondents perceive housework division as"fair",but the low index level indicates this perception mostly stems from normative adaptation rather than objective balance.This study provides empirical evidence for optimizing family labor allocation and promoting gender equality.
文摘This paper presents a new criterion for determining the unloading points quantitatively and consistently in a multi-stage triaxial test.The radial strain gradient(RSG)is first introduced as an arc tangent function of the rate of change of radial strain to time.RSG is observed to correlate closely with the stress state of a compressed sample,and reaches a horizontal asymptote as approaching failure.For a given rock type,RSG value at peak stress is almost the same,irrespective of the porosity and permeability.These findings lead to the development of RSG criterion:Unloading points can be precisely determined at the time when RSG reaches a pre-determined value that is a little smaller than or equal to the RSG at peak stress.The RSG criterion is validated against other criteria and the single-stage triaxial test on various types of rocks.Failure envelopes from the RSG criterion match well with those from single-stage tests.A practical procedure is recommended to use the RSG criterion:an unconfined compression or single-stage test is first conducted to determine the RSG at peak stress for one sample,the unloading point is then selected to be a value close to the RSG at peak stress,and the multi-stage test is finally performed on another sample using the pre-selected RSG unloading criterion.Generally,the RSG criterion is applicable for any type of rocks,especially brittle rocks,where other criteria are not suitable.Further,it can be practically implemented on the most available rock mechanical testing instruments.
基金supported by the National Natural Science Foundation of China(Grant No:52271300,52071337)National Key Research and Development Program of China(2022YFC2806501)+1 种基金High-tech Ship Research Projects Sponsored by MIIT(CBG2N21-4-25)Program for Changjiang Scholars and Innovative Research Team in University(Grant No.IRT14R58).
文摘A new hang-off system has been proposed to improve the security of risers in hang-off modes during typhoons.However,efficient anti-typhoon evacuation strategies have not been investigated.Optimiza-tion model and method for the anti-typhoon evacuation strategies should be researched.Therefore,multi-objective functions are proposed based on operation time,evacuation speed stability,and steering stability.An evacuation path model and a dynamic model of risers with the new hang-off system are developed for design variables and constraints.A multi-objective optimization model with high-dimensional variables and complex constraints is established.Finally,a three-stage optimization method based on genetic algorithm,least square method,and the penalty function method is proposed to solve the multi-objective optimization model.Optimization results show that the operation time can be reduced through operation parameter optimization,especially evacuation heading optimization.The optimal anti-typhoon strategy is evacuation with all risers suspended along a variable path when the direction angle is large,while evacuation with all risers suspended along a straight path at another di-rection angle.Besides,the influencing factors on anti-typhoon evacuation strategies indicate that the proposed optimization model and method have strong applicability to working conditions and remarkable optimization effects.
基金support from the National Nat-ural Science Foundation of China(Grant No.12474199)the Fundamental Research Funds for Central Universities of China(Grant No.20720240144),and 111 Project(B16029).
文摘Cell division is a fundamental biological process in which a parent cell divides into two daughter cells.The cell cortex,a thin layer primarily composed of actin filaments and myosin motors beneath the plasma membrane,plays a critical role in ensuring proper cell division.In this study,we apply a hydrodynamic model to describe the actin cortex as an active nematic surface,incorporating orientational order arising from actin filament alignment and anisotropic active stress produced by myosin motors.By analyzing the linearized dynamics,we investigate how shape,flow,and stress regulators evolve over time when the surface deviates slightly from a sphere.Our findings reveal that the active alignment of actin filaments,often overlooked in previous studies,is crucial for successful division.Furthermore,we demonstrate that a cortical chiral flow naturally emerges as a consequence of this active alignment.Overall,our results provide a mechanistic explanation for key phenomena observed during cell division,offering new insights into the role of active stress and filament alignment in cortical dynamics.
基金supported by the Nanjing Medical Science and Technology Development Project,China(Project No.:YKK23221)Open Project of Immune Cell Translational Research Center of Jiangning Hospital,Nanjing Medical University,China(Project No.:JNYYZXKY202216)+1 种基金General Project of Medical Education Collaborative Innovation Fund of Jiangsu University,China(Project No.:JDYY2023094)China Red Cross Foundation Medical Empowerment Charity Special Fund Project(Project No.:CRCF-YXFN-202302028).
文摘Acute respiratory distress syndrome(ARDS)is a common respiratory emergency,but current clinical treatment remains at the level of symptomatic support and there is a lack of effective targeted treatment measures.Our previous study confirmed that inhalation of hydrogen gas can reduce the acute lung injury of ARDS,but the application of hydrogen has flammable and explosive safety concerns.Drinking hydrogen-rich liquid or inhaling hydrogen gas has been shown to play an important role in scavenging reactive oxygen species and maintaining mitochondrial quality control balance,thus improving ARDS in patients and animal models.Coral calcium hydrogenation(CCH)is a new solid molecular hydrogen carrier prepared from coral calcium(CC).Whether and how CCH affects acute lung injury in ARDS remains unstudied.In this study,we observed the therapeutic effect of CCH on lipopolysaccharide(LPS)induced acute lung injury in ARDS mice.The survival rate of mice treated with CCH and hydrogen inhalation was found to be comparable,demonstrating a significant improvement compared to the untreated ARDS model group.CCH treatment significantly reduced pulmonary hemorrhage and edema,and improved pulmonary function and local microcirculation in ARDS mice.CCH promoted mitochondrial peripheral division in the early course of ARDS by activating mitochondrial thioredoxin 2(Trx2),improved lung mitochondrial dysfunction induced by LPS,and reduced oxidative stress damage.The results indicate that CCH is a highly efficient hydrogen-rich agent that can attenuate acute lung injury of ARDS by improving the mitochondrial function through Trx2 activation.
基金supported by the National Key Research and Development Program of China(Nos.2022YFA1205602,and 2023YFC3707801)the National Natural Science Foundation of China(Nos.U22A20402,22376073,21936003 and 22306119)China Postdoctoral Science Foundation(No.2023T160419).
文摘Nano zero-valent iron(nZVI)is a promising phosphate adsorbent for advanced phosphate removal.However,the rapid passivation of nZVI and the low activity of adsorption sites seriously limit its phosphate removal performance,accounting for its inapplicability to meet the emission criteria of 0.1 mg P/L phosphate.In this study,we report that the oxalate modification can inhibit the passivation of nZVI and alter the multi-stage phosphate adsorption mechanism by changing the adsorption sites.As expected,the stronger antipassivation ability of oxalate modified nZVI(OX-nZVI)strongly favored its phosphate adsorption.Interestingly,the oxalate modification endowed the surface Fe(III)sites with the lowest chemisorption energy and the fastest phosphate adsorption ability than the other adsorption sites,by in situ forming a Fe(III)-phosphate-oxalate ternary complex,therefore enabling an advanced phosphate removal process.At an initial phosphate concentration of 1.00 mg P/L,pH of 6.0 and a dosage of 0.3 g/L of adsorbents,OX-nZVI exhibited faster phosphate removal rate(0.11 g/mg/min)and lower residual phosphate level(0.02 mg P/L)than nZVI(0.055 g/mg/min and 0.19 mg P/L).This study sheds light on the importance of site manipulation in the development of high-performance adsorbents,and offers a facile surface modification strategy to prepare superior iron-basedmaterials for advanced phosphate removal.
基金Supported by Open Experimental Project in 2024 of Chuzhou University"Construction of Land and Space Planning System under the Background of Ecological Civilization"Humanities and Social Sciences Research Project Key Project of Anhui University in 2023"Digital Enabling Anhui Rural Human Settlements Environment Comprehensive Renovation Promotion Mechanism and Policy Optimization Research"(2023AH051571)+1 种基金Scientific Research Project of Chuzhou University"Research on the Mode,Mechanism and Promotion Path of Coordinated Development of Villages and Towns in the Suburbs of Metropolis from the Perspective of Three-dimensional Structure"(2023qd63)Digital Technology and Rural Revitalization Anhui Key Laboratory of Philosophy and Social Sciences 2024 Open Fund"Research on the Development Path and Supporting System of Rural Industry Driven by Digital Technology"(ZSKF202408).
文摘From the concept of the "Production-Living-Ecology" Spaces, this paper sorts out the theoretical basis, division principles, and division methods of the "Production-Living-Ecology" Spaces, and then proposes future prospects for them. The integration of theory and practice of "Production-Living-Ecology" Spaces is currently in a stage of in-depth exploration and practical application. Future research should fully recognize the importance and necessity of theoretical research on "Production-Living-Ecology" Spaces under the new situation, and consolidate the theoretical foundation for research on the development and protection of territorial space in the new era.
基金financial supports from Ministry of Science and Technology of the People’s Republic of China under Grant(No.2022YFC2203904)in part by Open Projects Foundation under Grant of State Key Laboratory of Optical Fiber and Cable Manufacture Technology(YOFC)(No.SKLD2306).
文摘Time division multiplexing(TDM)architecture is an important approach to creating sensor arrays for massive scale monitoring.But it is paradoxical for the TDM interferometric sensor array to keep a short delay fiber for high sensing resolution and meanwhile use low sampling rate for practical applications.In this paper,a phase matching sampling(PMS)paradigm is proposed to address the above contradiction.By matching the phase of the sampling clock with the delay fiber length,combining with multiple-pulses sampling strategy,the proposed PMS method can avoid collecting the redundant information,facilitating the decreasing of sampling rate as well as delay fiber length of the TDM sensing system.The proof-of-concept experiments on an 8-channel TDM interferometric system demonstrate that when the sampling rate is fixed at 20 MS/s,by applying the PMS algorithm,the delay fiber length can be shortened from 100 m to 1 m,compared with applying the conventional sampling method.It reduced the phase noise of the system by a factor of 10 at 1 mHz and by a factor of 50 at 1 Hz.The PMS algorithm for greatly reducing the sampling rate is expected to fuel the TDM interferometric sensor arrays for many applications.
基金supported by the National Key Research and Development Program of China(2022YFB2803800)the National Natural Science Foundation of China(U23B2047)the Zhejiang Provincial Natural Science Foundation of China(LDT23F04012F05).
文摘Large-capacity data transmission is increasingly required to meet the growing demands of big data and artificial intelligence applications.Wavelength-division multiplexing(WDM)technology is a reliable method of increasing link capacity by enabling multiple wavelength signals to be transmitted in a single channel.Here,for the first time,a large-capacity transmitter on thin-film lithium tantalate-on-insulator(LTOI)is demonstrated by monolithically integrating an 8-channel WDM and Mach–Zehnder interferometer(MZI)electro-optic modulators(EOMs).The integrated 8-channel WDM,comprised of 8 cascaded waveguide Bragg grating optical filters,realizes channel spacing of 16.8 nm,1-dB bandwidth of 15.4 nm,and thermal sensitivity of 10 pm/oC.The MZI EOMs show low direct current drift and 3-dB bandwidth beyond 67 GHz.Finally,the WDM transmitter achieves a data rate of 100 Gbps OOK and 200 Gbps PAM4 for a single channel,indicating the demonstrated total capacity of 1.6 Tbps.Therefore,the demonstrated large-capacity WDM transmitter will find many applications,such as artificial intelligence and data centers.
文摘WITHDRAWAL:Zhang,J.J.,Guo,Y.Q.,Qin,Z.Y.,Wei,C.T.,Hu,Q.H.,Vandeginste,V.,Miao,H.Y.,Yao,P.,and Zhang,P.F.,“Predicting Irreducible Water Saturation of Unconventional Reservoirs by Using NMR T2 Spectra:Methods of Morphological Division and Fractal Models”,Acta Geologica Sinica-English Edition(Accepted Article):https://doi.org/10.1111/1755-6724.15094.
文摘The Asia-Pacific region is the most dynamic part of the global economy.After over 50 years of continuously expanding trade,investment and industrial cooperation,the region has formed a highly-tied multi-level labor division system covering vertical integration and horizontal complementarity of industrial chains.From the V-shaped development model in the twentieth century to the East Asian production network in the twenty-first century,the intra-industry and intra-product division of labor in the Asia-Pacific region has been ever deepening.However,due to the region’s high dependence on the U.S.market,the division of labor model in the Asia-Pacific suffers structural problems and is relatively fragile.Under the shock of Trump 1.0,countries in the Asia-Pacific region were forced to make adaptive adjustments,causing short-term turmoil in the regional economic order.Trump’s strong return in 2025,driven by the“America First”principle,brought forth a series of policies with strong unilateralism,isolationism and protectionism tendencies within just a few months。
基金support from China National Natural Science Foundation (11672333)。
文摘The effectiveness of horizontal well multi-stage and multi-cluster fracturing in the fractured soft coal seam roof for coalbed methane(CBM) extraction has been demonstrated.This study focuses on the geological characteristics of the No.5 and No.11 coal seams in the Hancheng Block,Ordos Basin,China.A multi-functional,variable-size rock sample mold capable of securing the wellbore was developed to simulate layered formations comprising strata of varying lithology and thicknesses.A novel segmented fracturing simulation method based on an expandable pipe plugging technique is proposed.Large-scale true triaxial experiments were conducted to investigate the effects of horizontal wellbore location,perforation strategy,roof lithology,and vertical stress difference on fracture propagation,hydraulic energy variation,and the stimulated reservoir volume in horizontal wells targeting the soft coal seam roof.The results indicate that bilateral downward perforation with a phase angle of 120° optimizes hydraulic energy conservation,reduces operational costs,enhances fracture formation,and prevents fracturing failure caused by coal powder generation and migration.This perforation mode is thus considered optimal for coal seam roof fracturing.When the roof consists of sandstone,each perforation cluster tends to initiate a single dominant fracture with a regular geometry.In contrast,hydraulic fractures formed in mudstone roofs display diverse morphology.Due to its high strength,the sandstone roof requires significantly higher pressure for crack initiation and propagation,whereas the mudstone roof,with its strong water sensitivity,exhibits lower fracturing pressures.To mitigate inter-cluster interference,cluster spacing in mudstone roofs should be greater than that in sandstone roofs.Horizontal wellbore placement critically influences fracturing effectiveness.For indirect fracturing in sandstone roofs,an optimal position is 25 mm away from the lithological interface.In contrast,the optimal location for indirect fracturing in mudstone roofs is directly at the lithological interface with the coal seam.Higher vertical stress coefficients lead to increased fractu ring pressures and promote vertical,layer-penetrating fractures.A coefficient of 0.5 is identified as optimal for achieving effective indirect fracturing.This study provides valuable insights for the design and optimization of staged fracturing in horizontal wells targeting crushed soft coal seam roofs.
基金Supported by the National Natural Science Foundation of China,No.82002940 and No.82203336Shaanxi Natural Science Foundation,No.2023-JC-YB-166.
文摘BACKGROUND Hepatocellular carcinoma(HCC)ranks among the most prevalent and deadly malignancies,characterized by a high recurrence rate.Regulator of chromosome condensation 1(RCC1)serves as a principal guanine nucleotide exchange factor for ras-related nuclear protein guanosine triphosphatase(GTPase)and is implicated in various cancers.However,the role of RCC1 in HCC remains unex-plored.AIM To elucidate the functional significance and molecular mechanisms of RCC1 in HCC.METHODS Bioinformatics were to examine the expression levels of RCC1 in HCC and to assess its impact on the prognosis of this malignancy.The cell counting kit-8 assay and flow cytometry were utilized to evaluate the cell viability and cell cycle of HCC cells.Furthermore,quantitative reverse transcription and immunoblotting were to investigate the influence of RCC1 on cyclin associated proteins.RESULTS Bioinformatics analysis revealed that RCC1 was highly expressed in HCC and correlated with poor prognosis in HCC patients.Functional studies showed that RCC1 overexpression promoted the malignant phenotype of HCC cells,especially the proliferation of HCC cells,whereas RCC1 knockdown had the opposite effect.Mechanistically,we identied cell division cycle-associated(CDCA)8 as a downstream target of RCC1 in HCC.RCC1 overexpression markedly increased CDCA8 levels,consequently enhancing cell proliferation and survival in HCC cells.Additionally,we discovered that RCC1 contributed to the development and progression of HCC by activating the phosphoinositide 3-kinase/protein kinase B/cyclin-dependent kinase inhibitor 1a pathway through CDCA8.CONCLUSION Our study provides profound insights into the pivotal role of RCC1 in HCC and its potential as a therapeutic target.
