As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-...As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-nomic and trade interactions.Nonetheless,the safety of train operations remains a paramount concern,prompting extensive research into the dynamic behavior of critical components,which is essential to ensuring seamless and secure transportation services.This article commences by comprehensively reviewing the current landscape and evolutionary trajectory of dynamic model analysis for both traditional bearings and axle box bearings.Emphasis is placed on elucidating the profound influence of diverse bearing fault types on the system's kinematic state,alongside delving into the research methodologies employed in developing multi-physics field coupling models.Subsequently,it expounds on the content of investigations focusing on various wheel and track impairments,grounded in the dynamic modeling of the bearing vehicle coupling system.Concurrently,the intricate interplay between wheel-rail excitation and axle box bearing faults on the system's performance is elucidated.Concludingly,the article underscores the inadequacy of current multi-source fault diagnosis meth-odologies in tackling the intricacies of complex train operating environments,thereby highlighting its sig-nificance as a pressing and vital research agenda for the future.展开更多
The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR ...The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR bridges.Drive-by monitoring of bridge uneven settlement demonstrates significant potential due to its practicality,cost-effectiveness,and efficiency.However,existing drive-by methods for detecting bridge offset have limitations such as reliance on a single data source,low detection accuracy,and the inability to identify lateral deformations of bridges.This paper proposes a novel drive-by inspection method for spatial offset of HSR bridge based on multi-source data fusion of comprehensive inspection train.Firstly,dung beetle optimizer-variational mode decomposition was employed to achieve adaptive decomposition of non-stationary dynamic signals,and explore the hidden temporal relationships in the data.Subsequently,a long short-term memory neural network was developed to achieve feature fusion of multi-source signal and accurate prediction of spatial settlement of HSR bridge.A dataset of track irregularities and CRH380A high-speed train responses was generated using a 3D train-track-bridge interaction model,and the accuracy and effectiveness of the proposed hybrid deep learning model were numerically validated.Finally,the reliability of the proposed drive-by inspection method was further validated by analyzing the actual measurement data obtained from comprehensive inspection train.The research findings indicate that the proposed approach enables rapid and accurate detection of spatial offset in HSR bridge,ensuring the long-term operational safety of HSR bridges.展开更多
Domain adaptation aims to reduce the distribution gap between the training data(source domain)and the target data.This enables effective predictions even for domains not seen during training.However,most conventional ...Domain adaptation aims to reduce the distribution gap between the training data(source domain)and the target data.This enables effective predictions even for domains not seen during training.However,most conventional domain adaptation methods assume a single source domain,making them less suitable for modern deep learning settings that rely on diverse and large-scale datasets.To address this limitation,recent research has focused on Multi-Source Domain Adaptation(MSDA),which aims to learn effectively from multiple source domains.In this paper,we propose Efficient Domain Transition for Multi-source(EDTM),a novel and efficient framework designed to tackle two major challenges in existing MSDA approaches:(1)integrating knowledge across different source domains and(2)aligning label distributions between source and target domains.EDTM leverages an ensemble-based classifier expert mechanism to enhance the contribution of source domains that are more similar to the target domain.To further stabilize the learning process and improve performance,we incorporate imitation learning into the training of the target model.In addition,Maximum Classifier Discrepancy(MCD)is employed to align class-wise label distributions between the source and target domains.Experiments were conducted using Digits-Five,one of the most representative benchmark datasets for MSDA.The results show that EDTM consistently outperforms existing methods in terms of average classification accuracy.Notably,EDTM achieved significantly higher performance on target domains such as Modified National Institute of Standards and Technolog with blended background images(MNIST-M)and Street View House Numbers(SVHN)datasets,demonstrating enhanced generalization compared to baseline approaches.Furthermore,an ablation study analyzing the contribution of each loss component validated the effectiveness of the framework,highlighting the importance of each module in achieving optimal performance.展开更多
Benthic habitat mapping is an emerging discipline in the international marine field in recent years,providing an effective tool for marine spatial planning,marine ecological management,and decision-making applications...Benthic habitat mapping is an emerging discipline in the international marine field in recent years,providing an effective tool for marine spatial planning,marine ecological management,and decision-making applications.Seabed sediment classification is one of the main contents of seabed habitat mapping.In response to the impact of remote sensing imaging quality and the limitations of acoustic measurement range,where a single data source does not fully reflect the substrate type,we proposed a high-precision seabed habitat sediment classification method that integrates data from multiple sources.Based on WorldView-2 multi-spectral remote sensing image data and multibeam bathymetry data,constructed a random forests(RF)classifier with optimal feature selection.A seabed sediment classification experiment integrating optical remote sensing and acoustic remote sensing data was carried out in the shallow water area of Wuzhizhou Island,Hainan,South China.Different seabed sediment types,such as sand,seagrass,and coral reefs were effectively identified,with an overall classification accuracy of 92%.Experimental results show that RF matrix optimized by fusing multi-source remote sensing data for feature selection were better than the classification results of simple combinations of data sources,which improved the accuracy of seabed sediment classification.Therefore,the method proposed in this paper can be effectively applied to high-precision seabed sediment classification and habitat mapping around islands and reefs.展开更多
Accurate estimation of understory terrain has significant scientific importance for maintaining ecosystem balance and biodiversity conservation.Addressing the issue of inadequate representation of spatial heterogeneit...Accurate estimation of understory terrain has significant scientific importance for maintaining ecosystem balance and biodiversity conservation.Addressing the issue of inadequate representation of spatial heterogeneity when traditional forest topographic inversion methods consider the entire forest as the inversion unit,this study pro⁃poses a differentiated modeling approach to forest types based on refined land cover classification.Taking Puerto Ri⁃co and Maryland as study areas,a multi-dimensional feature system is constructed by integrating multi-source re⁃mote sensing data:ICESat-2 spaceborne LiDAR is used to obtain benchmark values for understory terrain,topo⁃graphic factors such as slope and aspect are extracted based on SRTM data,and vegetation cover characteristics are analyzed using Landsat-8 multispectral imagery.This study incorporates forest type as a classification modeling con⁃dition and applies the random forest algorithm to build differentiated topographic inversion models.Experimental re⁃sults indicate that,compared to traditional whole-area modeling methods(RMSE=5.06 m),forest type-based classi⁃fication modeling significantly improves the accuracy of understory terrain estimation(RMSE=2.94 m),validating the effectiveness of spatial heterogeneity modeling.Further sensitivity analysis reveals that canopy structure parame⁃ters(with RMSE variation reaching 4.11 m)exert a stronger regulatory effect on estimation accuracy compared to forest cover,providing important theoretical support for optimizing remote sensing models of forest topography.展开更多
The geological data are constructed in vector format in geographical information system (GIS) while other data such as remote sensing images, geographical data and geochemical data are saved in raster ones. This paper...The geological data are constructed in vector format in geographical information system (GIS) while other data such as remote sensing images, geographical data and geochemical data are saved in raster ones. This paper converts the vector data into 8 bit images according to their importance to mineralization each by programming. We can communicate the geological meaning with the raster images by this method. The paper also fuses geographical data and geochemical data with the programmed strata data. The result shows that image fusion can express different intensities effectively and visualize the structure characters in 2 dimensions. Furthermore, it also can produce optimized information from multi-source data and express them more directly.展开更多
To elucidate the fracturing mechanism of deep hard rock under complex disturbance environments,this study investigates the dynamic failure behavior of pre-damaged granite subjected to multi-source dynamic disturbances...To elucidate the fracturing mechanism of deep hard rock under complex disturbance environments,this study investigates the dynamic failure behavior of pre-damaged granite subjected to multi-source dynamic disturbances.Blasting vibration monitoring was conducted in a deep-buried drill-and-blast tunnel to characterize in-situ dynamic loading conditions.Subsequently,true triaxial compression tests incorporating multi-source disturbances were performed using a self-developed wide-low-frequency true triaxial system to simulate disturbance accumulation and damage evolution in granite.The results demonstrate that combined dynamic disturbances and unloading damage significantly accelerate strength degradation and trigger shear-slip failure along preferentially oriented blast-induced fractures,with strength reductions up to 16.7%.Layered failure was observed on the free surface of pre-damaged granite under biaxial loading,indicating a disturbance-induced fracture localization mechanism.Time-stress-fracture-energy coupling fields were constructed to reveal the spatiotemporal characteristics of fracture evolution.Critical precursor frequency bands(105-150,185-225,and 300-325 kHz)were identified,which serve as diagnostic signatures of impending failure.A dynamic instability mechanism driven by multi-source disturbance superposition and pre-damage evolution was established.Furthermore,a grouting-based wave-absorption control strategy was proposed to mitigate deep dynamic disasters by attenuating disturbance amplitude and reducing excitation frequency.展开更多
The SiO_(2) inverse opal photonic crystals(PC)with a three-dimensional macroporous structure were fabricated by the sacrificial template method,followed by infiltration of a pyrene derivative,1-(pyren-8-yl)but-3-en-1-...The SiO_(2) inverse opal photonic crystals(PC)with a three-dimensional macroporous structure were fabricated by the sacrificial template method,followed by infiltration of a pyrene derivative,1-(pyren-8-yl)but-3-en-1-amine(PEA),to achieve a formaldehyde(FA)-sensitive and fluorescence-enhanced sensing film.Utilizing the specific Aza-Cope rearrangement reaction of allylamine of PEA and FA to generate a strong fluorescent product emitted at approximately 480 nm,we chose a PC whose blue band edge of stopband overlapped with the fluorescence emission wavelength.In virtue of the fluorescence enhancement property derived from slow photon effect of PC,FA was detected highly selectively and sensitively.The limit of detection(LoD)was calculated to be 1.38 nmol/L.Furthermore,the fast detection of FA(within 1 min)is realized due to the interconnected three-dimensional macroporous structure of the inverse opal PC and its high specific surface area.The prepared sensing film can be used for the detection of FA in air,aquatic products and living cells.The very close FA content in indoor air to the result from FA detector,the recovery rate of 101.5%for detecting FA in aquatic products and fast fluorescence imaging in 2 min for living cells demonstrate the reliability and accuracy of our method in practical applications.展开更多
Due to the development of cloud computing and machine learning,users can upload their data to the cloud for machine learning model training.However,dishonest clouds may infer user data,resulting in user data leakage.P...Due to the development of cloud computing and machine learning,users can upload their data to the cloud for machine learning model training.However,dishonest clouds may infer user data,resulting in user data leakage.Previous schemes have achieved secure outsourced computing,but they suffer from low computational accuracy,difficult-to-handle heterogeneous distribution of data from multiple sources,and high computational cost,which result in extremely poor user experience and expensive cloud computing costs.To address the above problems,we propose amulti-precision,multi-sourced,andmulti-key outsourcing neural network training scheme.Firstly,we design a multi-precision functional encryption computation based on Euclidean division.Second,we design the outsourcing model training algorithm based on a multi-precision functional encryption with multi-sourced heterogeneity.Finally,we conduct experiments on three datasets.The results indicate that our framework achieves an accuracy improvement of 6%to 30%.Additionally,it offers a memory space optimization of 1.0×2^(24) times compared to the previous best approach.展开更多
Accurate monitoring of track irregularities is very helpful to improving the vehicle operation quality and to formulating appropriate track maintenance strategies.Existing methods have the problem that they rely on co...Accurate monitoring of track irregularities is very helpful to improving the vehicle operation quality and to formulating appropriate track maintenance strategies.Existing methods have the problem that they rely on complex signal processing algorithms and lack multi-source data analysis.Driven by multi-source measurement data,including the axle box,the bogie frame and the carbody accelerations,this paper proposes a track irregularities monitoring network(TIMNet)based on deep learning methods.TIMNet uses the feature extraction capability of convolutional neural networks and the sequence map-ping capability of the long short-term memory model to explore the mapping relationship between vehicle accelerations and track irregularities.The particle swarm optimization algorithm is used to optimize the network parameters,so that both the vertical and lateral track irregularities can be accurately identified in the time and spatial domains.The effectiveness and superiority of the proposed TIMNet is analyzed under different simulation conditions using a vehicle dynamics model.Field tests are conducted to prove the availability of the proposed TIMNet in quantitatively monitoring vertical and lateral track irregularities.Furthermore,comparative tests show that the TIMNet has a better fitting degree and timeliness in monitoring track irregularities(vertical R2 of 0.91,lateral R2 of 0.84 and time cost of 10 ms),compared to other classical regression.The test also proves that the TIMNet has a better anti-interference ability than other regression models.展开更多
In the heterogeneous power internet of things(IoT)environment,data signals are acquired to support different business systems to realize advanced intelligent applications,with massive,multi-source,heterogeneous and ot...In the heterogeneous power internet of things(IoT)environment,data signals are acquired to support different business systems to realize advanced intelligent applications,with massive,multi-source,heterogeneous and other characteristics.Reliable perception of information and efficient transmission of energy in multi-source heterogeneous environments are crucial issues.Compressive sensing(CS),as an effective method of signal compression and transmission,can accurately recover the original signal only by very few sampling.In this paper,we study a new method of multi-source heterogeneous data signal reconstruction of power IoT based on compressive sensing technology.Based on the traditional compressive sensing technology to directly recover multi-source heterogeneous signals,we fully use the interference subspace information to design the measurement matrix,which directly and effectively eliminates the interference while making the measurement.The measure matrix is optimized by minimizing the average cross-coherence of the matrix,and the reconstruction performance of the new method is further improved.Finally,the effectiveness of the new method with different parameter settings under different multi-source heterogeneous data signal cases is verified by using orthogonal matching pursuit(OMP)and sparsity adaptive matching pursuit(SAMP)for considering the actual environment with prior information utilization of signal sparsity and no prior information utilization of signal sparsity.展开更多
This paper deeply discusses the causes of gear howling noise,the identification and analysis of multi-source excitation,the transmission path of dynamic noise,simulation and experimental research,case analysis,optimiz...This paper deeply discusses the causes of gear howling noise,the identification and analysis of multi-source excitation,the transmission path of dynamic noise,simulation and experimental research,case analysis,optimization effect,etc.,aiming to better provide a certain guideline and reference for relevant researchers.展开更多
With the acceleration of intelligent transformation of energy system,the monitoring of equipment operation status and optimization of production process in thermal power plants face the challenge of multi-source heter...With the acceleration of intelligent transformation of energy system,the monitoring of equipment operation status and optimization of production process in thermal power plants face the challenge of multi-source heterogeneous data integration.In view of the heterogeneous characteristics of physical sensor data,including temperature,vibration and pressure that generated by boilers,steam turbines and other key equipment and real-time working condition data of SCADA system,this paper proposes a multi-source heterogeneous data fusion and analysis platform for thermal power plants based on edge computing and deep learning.By constructing a multi-level fusion architecture,the platform adopts dynamic weight allocation strategy and 5D digital twin model to realize the collaborative analysis of physical sensor data,simulation calculation results and expert knowledge.The data fusion module combines Kalman filter,wavelet transform and Bayesian estimation method to solve the problem of data time series alignment and dimension difference.Simulation results show that the data fusion accuracy can be improved to more than 98%,and the calculation delay can be controlled within 500 ms.The data analysis module integrates Dymola simulation model and AERMOD pollutant diffusion model,supports the cascade analysis of boiler combustion efficiency prediction and flue gas emission monitoring,system response time is less than 2 seconds,and data consistency verification accuracy reaches 99.5%.展开更多
Multi-source data fusion provides high-precision spatial situational awareness essential for analyzing granular urban social activities.This study used Shanghai’s catering industry as a case study,leveraging electron...Multi-source data fusion provides high-precision spatial situational awareness essential for analyzing granular urban social activities.This study used Shanghai’s catering industry as a case study,leveraging electronic reviews and consumer data sourced from third-party restaurant platforms collected in 2021.By performing weighted processing on two-dimensional point-of-interest(POI)data,clustering hotspots of high-dimensional restaurant data were identified.A hierarchical network of restaurant hotspots was constructed following the Central Place Theory(CPT)framework,while the Geo-Informatic Tupu method was employed to resolve the challenges posed by network deformation in multi-scale processes.These findings suggest the necessity of enhancing the spatial balance of Shanghai’s urban centers by moderately increasing the number and service capacity of suburban centers at the urban periphery.Such measures would contribute to a more optimized urban structure and facilitate the outward dispersion of comfort-oriented facilities such as the restaurant industry.At a finer spatial scale,the distribution of restaurant hotspots demonstrates a polycentric and symmetric spatial pattern,with a developmental trend radiating outward along the city’s ring roads.This trend can be attributed to the efforts of restaurants to establish connections with other urban functional spaces,leading to the reconfiguration of urban spaces,expansion of restaurant-dedicated land use,and the reorganization of associated commercial activities.The results validate the existence of a polycentric urban structure in Shanghai but also highlight the instability of the restaurant hotspot network during cross-scale transitions.展开更多
Taking the Ming Tombs Forest Farm in Beijing as the research object,this research applied multi-source data fusion and GIS heat-map overlay analysis techniques,systematically collected bird observation point data from...Taking the Ming Tombs Forest Farm in Beijing as the research object,this research applied multi-source data fusion and GIS heat-map overlay analysis techniques,systematically collected bird observation point data from the Global Biodiversity Information Facility(GBIF),population distribution data from the Oak Ridge National Laboratory(ORNL)in the United States,as well as information on the composition of tree species in suitable forest areas for birds and the forest geographical information of the Ming Tombs Forest Farm,which is based on literature research and field investigations.By using GIS technology,spatial processing was carried out on bird observation points and population distribution data to identify suitable bird-watching areas in different seasons.Then,according to the suitability value range,these areas were classified into different grades(from unsuitable to highly suitable).The research findings indicated that there was significant spatial heterogeneity in the bird-watching suitability of the Ming Tombs Forest Farm.The north side of the reservoir was generally a core area with high suitability in all seasons.The deep-aged broad-leaved mixed forests supported the overlapping co-existence of the ecological niches of various bird species,such as the Zosterops simplex and Urocissa erythrorhyncha.In contrast,the shallow forest-edge coniferous pure forests and mixed forests were more suitable for specialized species like Carduelis sinica.The southern urban area and the core area of the mausoleums had relatively low suitability due to ecological fragmentation or human interference.Based on these results,this paper proposed a three-level protection framework of“core area conservation—buffer zone management—isolation zone construction”and a spatio-temporal coordinated human-bird co-existence strategy.It was also suggested that the human-bird co-existence space could be optimized through measures such as constructing sound and light buffer interfaces,restoring ecological corridors,and integrating cultural heritage elements.This research provided an operational technical approach and decision-making support for the scientific planning of bird-watching sites and the coordination of ecological protection and tourism development.展开更多
As coal mining progresses to greater depths,controlling the stability of surrounding rock in deep roadways has become an increasingly complex challenge.Although four-dimensional(4D)support theoretically offers unique ...As coal mining progresses to greater depths,controlling the stability of surrounding rock in deep roadways has become an increasingly complex challenge.Although four-dimensional(4D)support theoretically offers unique advantages in maintaining the stability of rock mass,the disaster evolution processes and multi-source information response characteristics in deep roadways with 4D support remain unclear.Consequently,a large-scale physical model testing system and self-designed 4D support components were employed to conduct similarity model tests on the surrounding rock failure process under unsupported(U-1),traditional bolt-mesh-cable support(T-2),and 4D support(4D-R-3)conditions.Combined with multi-source monitoring techniques,including stress–strain,digital image correlation(DIC),acoustic emission(AE),microseismic(MS),parallel electric(PE),and electromagnetic radiation(EMR),the mechanical behavior and multi-source information responses were comprehensively analyzed.The results show that the peak stress and displacement of the models are positively correlated with the support strength.The multi-source information exhibits distinct response characteristics under different supports.The response frequency,energy,and fluctuationsof AE,MS,and EMR signals,along with the apparent resistivity(AR)high-resistivity zone,follow the trend U-1>T-2>4D-R-3.Furthermore,multi-source information exhibits significantdifferences in sensitivity across different phases.The AE,MS,and EMR signals exhibit active responses to rock mass activity at each phase.However,AR signals are only sensitive to the fracture propagation during the plastic yield and failure phases.In summary,the 4D support significantlyenhances the bearing capacity and plastic deformation of the models,while substantially reducing the frequency,energy,and fluctuationsof multi-source signals.展开更多
Vector transducer can simultaneously measure components of particle velocity as well as pressure at some point in sound field. In this paper, a series of equations are obtained from the correlation of particle velocit...Vector transducer can simultaneously measure components of particle velocity as well as pressure at some point in sound field. In this paper, a series of equations are obtained from the correlation of particle velocity and pressure of the incident wave field, the error of each equation with white noise is studied, and Differential Evolution is used in solving the equations to distinguish multi-sources. Results of computer simulation show that Differential Evolution has more superiority than Genetic Algorithms on the rate and precision of convergence under the same condition.展开更多
Modern intelligent systems,such as autonomous vehicles and face recognition,must continuously adapt to new scenarios while preserving their ability to handle previously encountered situations.However,when neural netwo...Modern intelligent systems,such as autonomous vehicles and face recognition,must continuously adapt to new scenarios while preserving their ability to handle previously encountered situations.However,when neural networks learn new classes sequentially,they suffer from catastrophic forgetting—the tendency to lose knowledge of earlier classes.This challenge,which lies at the core of class-incremental learning,severely limits the deployment of continual learning systems in real-world applications with streaming data.Existing approaches,including rehearsalbased methods and knowledge distillation techniques,have attempted to address this issue but often struggle to effectively preserve decision boundaries and discriminative features under limited memory constraints.To overcome these limitations,we propose a support vector-guided framework for class-incremental learning.The framework integrates an enhanced feature extractor with a Support Vector Machine classifier,which generates boundary-critical support vectors to guide both replay and distillation.Building on this architecture,we design a joint feature retention strategy that combines boundary proximity with feature diversity,and a Support Vector Distillation Loss that enforces dual alignment in decision and semantic spaces.In addition,triple attention modules are incorporated into the feature extractor to enhance representation power.Extensive experiments on CIFAR-100 and Tiny-ImageNet demonstrate effective improvements.On CIFAR-100 and Tiny-ImageNet with 5 tasks,our method achieves 71.68%and 58.61%average accuracy,outperforming strong baselines by 3.34%and 2.05%.These advantages are consistently observed across different task splits,highlighting the robustness and generalization of the proposed approach.Beyond benchmark evaluations,the framework also shows potential in few-shot and resource-constrained applications such as edge computing and mobile robotics.展开更多
The development of clinical candidates that modify the natural progression of sporadic Parkinson's disease and related synucleinopathies is a praiseworthy endeavor,but extremely challenging.Therapeutic candidates ...The development of clinical candidates that modify the natural progression of sporadic Parkinson's disease and related synucleinopathies is a praiseworthy endeavor,but extremely challenging.Therapeutic candidates that were successful in preclinical Parkinson's disease animal models have repeatedly failed when tested in clinical trials.While these failures have many possible explanations,it is perhaps time to recognize that the problem lies with the animal models rather than the putative candidate.In other words,the lack of adequate animal models of Parkinson's disease currently represents the main barrier to preclinical identification of potential disease-modifying therapies likely to succeed in clinical trials.However,this barrier may be overcome by the recent introduction of novel generations of viral vectors coding for different forms of alpha-synuclein species and related genes.Although still facing several limitations,these models have managed to mimic the known neuropathological hallmarks of Parkinson's disease with unprecedented accuracy,delineating a more optimistic scenario for the near future.展开更多
Fluidic Thrust Vectoring(FTV)is used for the yaw attitude control of tailless flying wing,which can significantly improve stealth performance,maneuverability and lateral/heading maneuverability.The FTV control scheme ...Fluidic Thrust Vectoring(FTV)is used for the yaw attitude control of tailless flying wing,which can significantly improve stealth performance,maneuverability and lateral/heading maneuverability.The FTV control scheme of co-directional secondary flow was designed based on a 30 kgf thrust turbojet engine,an equivalent rudder deflection control variable of Mass Flow Combination(MFC)was proposed,and a control model was established to form a FTV control system scheme,which was integrated with the flight control system of a 100 kg tailless flying wing with medium aspect ratio to achieve closed-loop control of the yaw attitude based on FTV.The heading stability augmentation and maneuvering control characteristics and time response characteristics of tailless flying wing by FTV were quantitatively studied through virtual flight test in a wind tunnel at a wind speed of 35 m/s.The results show that the control strategy based on MFC achieves bidirectional continuous and stable control of thrust vector angle in a range of±11°,and the thrust vector angle varies monotonically with MFC;the co-directional FTV realizes bidirectional continuous and stable control of the yaw attitude of tailless flying wing,without longitudinal/lateral coupling moment.The increment of the maximum yawing moment coefficient is 0.0029,the maximum yaw rate is 7.55(°)/s,and the response time of the yaw rate of the vectoring nozzle actuated by the secondary flow is about 0.06 s,which satisfies the heading stability augmentation and maneuvering control response requirements of the aircraft with statically unstable heading,and provides new control means for the heading rudderless attitude control of tailless flying wing.展开更多
基金Supported by the National Natural Science Foundation of China(Grant Nos.12393783,12302067,12172235,52072249)Joint Funds of the National Natural Science Foundation of China(Grant No.U24A2003)+3 种基金College Education Scientific Research Project of Hebei Province(Grant No.JZX2024006)Central Guiding Local Scientific and Technological Development Funding Project(Grant No.246Z2206G)the Key Research Project of China State Railway Group Co.,Ltd.(Grant No.N2024T009)S&T Program of Hebei(Grant No.21567622H).
文摘As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-nomic and trade interactions.Nonetheless,the safety of train operations remains a paramount concern,prompting extensive research into the dynamic behavior of critical components,which is essential to ensuring seamless and secure transportation services.This article commences by comprehensively reviewing the current landscape and evolutionary trajectory of dynamic model analysis for both traditional bearings and axle box bearings.Emphasis is placed on elucidating the profound influence of diverse bearing fault types on the system's kinematic state,alongside delving into the research methodologies employed in developing multi-physics field coupling models.Subsequently,it expounds on the content of investigations focusing on various wheel and track impairments,grounded in the dynamic modeling of the bearing vehicle coupling system.Concurrently,the intricate interplay between wheel-rail excitation and axle box bearing faults on the system's performance is elucidated.Concludingly,the article underscores the inadequacy of current multi-source fault diagnosis meth-odologies in tackling the intricacies of complex train operating environments,thereby highlighting its sig-nificance as a pressing and vital research agenda for the future.
基金sponsored by the National Natural Science Foundation of China(Grant No.52178100).
文摘The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR bridges.Drive-by monitoring of bridge uneven settlement demonstrates significant potential due to its practicality,cost-effectiveness,and efficiency.However,existing drive-by methods for detecting bridge offset have limitations such as reliance on a single data source,low detection accuracy,and the inability to identify lateral deformations of bridges.This paper proposes a novel drive-by inspection method for spatial offset of HSR bridge based on multi-source data fusion of comprehensive inspection train.Firstly,dung beetle optimizer-variational mode decomposition was employed to achieve adaptive decomposition of non-stationary dynamic signals,and explore the hidden temporal relationships in the data.Subsequently,a long short-term memory neural network was developed to achieve feature fusion of multi-source signal and accurate prediction of spatial settlement of HSR bridge.A dataset of track irregularities and CRH380A high-speed train responses was generated using a 3D train-track-bridge interaction model,and the accuracy and effectiveness of the proposed hybrid deep learning model were numerically validated.Finally,the reliability of the proposed drive-by inspection method was further validated by analyzing the actual measurement data obtained from comprehensive inspection train.The research findings indicate that the proposed approach enables rapid and accurate detection of spatial offset in HSR bridge,ensuring the long-term operational safety of HSR bridges.
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.RS-2024-00406320)the Institute of Information&Communica-tions Technology Planning&Evaluation(IITP)-Innovative Human Resource Development for Local Intellectualization Program Grant funded by the Korea government(MSIT)(IITP-2026-RS-2023-00259678).
文摘Domain adaptation aims to reduce the distribution gap between the training data(source domain)and the target data.This enables effective predictions even for domains not seen during training.However,most conventional domain adaptation methods assume a single source domain,making them less suitable for modern deep learning settings that rely on diverse and large-scale datasets.To address this limitation,recent research has focused on Multi-Source Domain Adaptation(MSDA),which aims to learn effectively from multiple source domains.In this paper,we propose Efficient Domain Transition for Multi-source(EDTM),a novel and efficient framework designed to tackle two major challenges in existing MSDA approaches:(1)integrating knowledge across different source domains and(2)aligning label distributions between source and target domains.EDTM leverages an ensemble-based classifier expert mechanism to enhance the contribution of source domains that are more similar to the target domain.To further stabilize the learning process and improve performance,we incorporate imitation learning into the training of the target model.In addition,Maximum Classifier Discrepancy(MCD)is employed to align class-wise label distributions between the source and target domains.Experiments were conducted using Digits-Five,one of the most representative benchmark datasets for MSDA.The results show that EDTM consistently outperforms existing methods in terms of average classification accuracy.Notably,EDTM achieved significantly higher performance on target domains such as Modified National Institute of Standards and Technolog with blended background images(MNIST-M)and Street View House Numbers(SVHN)datasets,demonstrating enhanced generalization compared to baseline approaches.Furthermore,an ablation study analyzing the contribution of each loss component validated the effectiveness of the framework,highlighting the importance of each module in achieving optimal performance.
基金Supported by the National Natural Science Foundation of China(Nos.42376185,41876111)the Shandong Provincial Natural Science Foundation(No.ZR2023MD073)。
文摘Benthic habitat mapping is an emerging discipline in the international marine field in recent years,providing an effective tool for marine spatial planning,marine ecological management,and decision-making applications.Seabed sediment classification is one of the main contents of seabed habitat mapping.In response to the impact of remote sensing imaging quality and the limitations of acoustic measurement range,where a single data source does not fully reflect the substrate type,we proposed a high-precision seabed habitat sediment classification method that integrates data from multiple sources.Based on WorldView-2 multi-spectral remote sensing image data and multibeam bathymetry data,constructed a random forests(RF)classifier with optimal feature selection.A seabed sediment classification experiment integrating optical remote sensing and acoustic remote sensing data was carried out in the shallow water area of Wuzhizhou Island,Hainan,South China.Different seabed sediment types,such as sand,seagrass,and coral reefs were effectively identified,with an overall classification accuracy of 92%.Experimental results show that RF matrix optimized by fusing multi-source remote sensing data for feature selection were better than the classification results of simple combinations of data sources,which improved the accuracy of seabed sediment classification.Therefore,the method proposed in this paper can be effectively applied to high-precision seabed sediment classification and habitat mapping around islands and reefs.
基金Supported by the National Natural Science Foundation of China(42401488,42071351)the National Key Research and Development Program of China(2020YFA0608501,2017YFB0504204)+4 种基金the Liaoning Revitalization Talents Program(XLYC1802027)the Talent Recruited Program of the Chinese Academy of Science(Y938091)the Project Supported Discipline Innovation Team of the Liaoning Technical University(LNTU20TD-23)the Liaoning Province Doctoral Research Initiation Fund Program(2023-BS-202)the Basic Research Projects of Liaoning Department of Education(JYTQN2023202)。
文摘Accurate estimation of understory terrain has significant scientific importance for maintaining ecosystem balance and biodiversity conservation.Addressing the issue of inadequate representation of spatial heterogeneity when traditional forest topographic inversion methods consider the entire forest as the inversion unit,this study pro⁃poses a differentiated modeling approach to forest types based on refined land cover classification.Taking Puerto Ri⁃co and Maryland as study areas,a multi-dimensional feature system is constructed by integrating multi-source re⁃mote sensing data:ICESat-2 spaceborne LiDAR is used to obtain benchmark values for understory terrain,topo⁃graphic factors such as slope and aspect are extracted based on SRTM data,and vegetation cover characteristics are analyzed using Landsat-8 multispectral imagery.This study incorporates forest type as a classification modeling con⁃dition and applies the random forest algorithm to build differentiated topographic inversion models.Experimental re⁃sults indicate that,compared to traditional whole-area modeling methods(RMSE=5.06 m),forest type-based classi⁃fication modeling significantly improves the accuracy of understory terrain estimation(RMSE=2.94 m),validating the effectiveness of spatial heterogeneity modeling.Further sensitivity analysis reveals that canopy structure parame⁃ters(with RMSE variation reaching 4.11 m)exert a stronger regulatory effect on estimation accuracy compared to forest cover,providing important theoretical support for optimizing remote sensing models of forest topography.
文摘The geological data are constructed in vector format in geographical information system (GIS) while other data such as remote sensing images, geographical data and geochemical data are saved in raster ones. This paper converts the vector data into 8 bit images according to their importance to mineralization each by programming. We can communicate the geological meaning with the raster images by this method. The paper also fuses geographical data and geochemical data with the programmed strata data. The result shows that image fusion can express different intensities effectively and visualize the structure characters in 2 dimensions. Furthermore, it also can produce optimized information from multi-source data and express them more directly.
基金supported by the National Key R&D Program of China(No.2023YFB2603602)the National Natural Science Foundation of China(Nos.52222810 and 52178383).
文摘To elucidate the fracturing mechanism of deep hard rock under complex disturbance environments,this study investigates the dynamic failure behavior of pre-damaged granite subjected to multi-source dynamic disturbances.Blasting vibration monitoring was conducted in a deep-buried drill-and-blast tunnel to characterize in-situ dynamic loading conditions.Subsequently,true triaxial compression tests incorporating multi-source disturbances were performed using a self-developed wide-low-frequency true triaxial system to simulate disturbance accumulation and damage evolution in granite.The results demonstrate that combined dynamic disturbances and unloading damage significantly accelerate strength degradation and trigger shear-slip failure along preferentially oriented blast-induced fractures,with strength reductions up to 16.7%.Layered failure was observed on the free surface of pre-damaged granite under biaxial loading,indicating a disturbance-induced fracture localization mechanism.Time-stress-fracture-energy coupling fields were constructed to reveal the spatiotemporal characteristics of fracture evolution.Critical precursor frequency bands(105-150,185-225,and 300-325 kHz)were identified,which serve as diagnostic signatures of impending failure.A dynamic instability mechanism driven by multi-source disturbance superposition and pre-damage evolution was established.Furthermore,a grouting-based wave-absorption control strategy was proposed to mitigate deep dynamic disasters by attenuating disturbance amplitude and reducing excitation frequency.
基金supported by the National Natural Science Foundation of China(21663032 and 22061041)the Open Sharing Platform for Scientific and Technological Resources of Shaanxi Province(2021PT-004)the National Innovation and Entrepreneurship Training Program for College Students of China(S202110719044)。
文摘The SiO_(2) inverse opal photonic crystals(PC)with a three-dimensional macroporous structure were fabricated by the sacrificial template method,followed by infiltration of a pyrene derivative,1-(pyren-8-yl)but-3-en-1-amine(PEA),to achieve a formaldehyde(FA)-sensitive and fluorescence-enhanced sensing film.Utilizing the specific Aza-Cope rearrangement reaction of allylamine of PEA and FA to generate a strong fluorescent product emitted at approximately 480 nm,we chose a PC whose blue band edge of stopband overlapped with the fluorescence emission wavelength.In virtue of the fluorescence enhancement property derived from slow photon effect of PC,FA was detected highly selectively and sensitively.The limit of detection(LoD)was calculated to be 1.38 nmol/L.Furthermore,the fast detection of FA(within 1 min)is realized due to the interconnected three-dimensional macroporous structure of the inverse opal PC and its high specific surface area.The prepared sensing film can be used for the detection of FA in air,aquatic products and living cells.The very close FA content in indoor air to the result from FA detector,the recovery rate of 101.5%for detecting FA in aquatic products and fast fluorescence imaging in 2 min for living cells demonstrate the reliability and accuracy of our method in practical applications.
基金supported by Natural Science Foundation of China(Nos.62303126,62362008,author Z.Z,https://www.nsfc.gov.cn/,accessed on 20 December 2024)Major Scientific and Technological Special Project of Guizhou Province([2024]014)+2 种基金Guizhou Provincial Science and Technology Projects(No.ZK[2022]General149) ,author Z.Z,https://kjt.guizhou.gov.cn/,accessed on 20 December 2024)The Open Project of the Key Laboratory of Computing Power Network and Information Security,Ministry of Education under Grant 2023ZD037,author Z.Z,https://www.gzu.edu.cn/,accessed on 20 December 2024)Open Research Project of the State Key Laboratory of Industrial Control Technology,Zhejiang University,China(No.ICT2024B25),author Z.Z,https://www.gzu.edu.cn/,accessed on 20 December 2024).
文摘Due to the development of cloud computing and machine learning,users can upload their data to the cloud for machine learning model training.However,dishonest clouds may infer user data,resulting in user data leakage.Previous schemes have achieved secure outsourced computing,but they suffer from low computational accuracy,difficult-to-handle heterogeneous distribution of data from multiple sources,and high computational cost,which result in extremely poor user experience and expensive cloud computing costs.To address the above problems,we propose amulti-precision,multi-sourced,andmulti-key outsourcing neural network training scheme.Firstly,we design a multi-precision functional encryption computation based on Euclidean division.Second,we design the outsourcing model training algorithm based on a multi-precision functional encryption with multi-sourced heterogeneity.Finally,we conduct experiments on three datasets.The results indicate that our framework achieves an accuracy improvement of 6%to 30%.Additionally,it offers a memory space optimization of 1.0×2^(24) times compared to the previous best approach.
基金supported by the Sichuan Science and Technology Program(Nos.2024JDRC0100 and 2023YFQ0091)the National Natural Science Foundation of China(Nos.U21A20167 and 52475138)the Scientific Research Foundation of the State Key Laboratory of Rail Transit Vehicle System(No.2024RVL-T08).
文摘Accurate monitoring of track irregularities is very helpful to improving the vehicle operation quality and to formulating appropriate track maintenance strategies.Existing methods have the problem that they rely on complex signal processing algorithms and lack multi-source data analysis.Driven by multi-source measurement data,including the axle box,the bogie frame and the carbody accelerations,this paper proposes a track irregularities monitoring network(TIMNet)based on deep learning methods.TIMNet uses the feature extraction capability of convolutional neural networks and the sequence map-ping capability of the long short-term memory model to explore the mapping relationship between vehicle accelerations and track irregularities.The particle swarm optimization algorithm is used to optimize the network parameters,so that both the vertical and lateral track irregularities can be accurately identified in the time and spatial domains.The effectiveness and superiority of the proposed TIMNet is analyzed under different simulation conditions using a vehicle dynamics model.Field tests are conducted to prove the availability of the proposed TIMNet in quantitatively monitoring vertical and lateral track irregularities.Furthermore,comparative tests show that the TIMNet has a better fitting degree and timeliness in monitoring track irregularities(vertical R2 of 0.91,lateral R2 of 0.84 and time cost of 10 ms),compared to other classical regression.The test also proves that the TIMNet has a better anti-interference ability than other regression models.
基金supported by National Natural Science Foundation of China(12174350)Science and Technology Project of State Grid Henan Electric Power Company(5217Q0240008).
文摘In the heterogeneous power internet of things(IoT)environment,data signals are acquired to support different business systems to realize advanced intelligent applications,with massive,multi-source,heterogeneous and other characteristics.Reliable perception of information and efficient transmission of energy in multi-source heterogeneous environments are crucial issues.Compressive sensing(CS),as an effective method of signal compression and transmission,can accurately recover the original signal only by very few sampling.In this paper,we study a new method of multi-source heterogeneous data signal reconstruction of power IoT based on compressive sensing technology.Based on the traditional compressive sensing technology to directly recover multi-source heterogeneous signals,we fully use the interference subspace information to design the measurement matrix,which directly and effectively eliminates the interference while making the measurement.The measure matrix is optimized by minimizing the average cross-coherence of the matrix,and the reconstruction performance of the new method is further improved.Finally,the effectiveness of the new method with different parameter settings under different multi-source heterogeneous data signal cases is verified by using orthogonal matching pursuit(OMP)and sparsity adaptive matching pursuit(SAMP)for considering the actual environment with prior information utilization of signal sparsity and no prior information utilization of signal sparsity.
文摘This paper deeply discusses the causes of gear howling noise,the identification and analysis of multi-source excitation,the transmission path of dynamic noise,simulation and experimental research,case analysis,optimization effect,etc.,aiming to better provide a certain guideline and reference for relevant researchers.
文摘With the acceleration of intelligent transformation of energy system,the monitoring of equipment operation status and optimization of production process in thermal power plants face the challenge of multi-source heterogeneous data integration.In view of the heterogeneous characteristics of physical sensor data,including temperature,vibration and pressure that generated by boilers,steam turbines and other key equipment and real-time working condition data of SCADA system,this paper proposes a multi-source heterogeneous data fusion and analysis platform for thermal power plants based on edge computing and deep learning.By constructing a multi-level fusion architecture,the platform adopts dynamic weight allocation strategy and 5D digital twin model to realize the collaborative analysis of physical sensor data,simulation calculation results and expert knowledge.The data fusion module combines Kalman filter,wavelet transform and Bayesian estimation method to solve the problem of data time series alignment and dimension difference.Simulation results show that the data fusion accuracy can be improved to more than 98%,and the calculation delay can be controlled within 500 ms.The data analysis module integrates Dymola simulation model and AERMOD pollutant diffusion model,supports the cascade analysis of boiler combustion efficiency prediction and flue gas emission monitoring,system response time is less than 2 seconds,and data consistency verification accuracy reaches 99.5%.
基金Under the auspices of the Key Program of National Natural Science Foundation of China(No.42030409)。
文摘Multi-source data fusion provides high-precision spatial situational awareness essential for analyzing granular urban social activities.This study used Shanghai’s catering industry as a case study,leveraging electronic reviews and consumer data sourced from third-party restaurant platforms collected in 2021.By performing weighted processing on two-dimensional point-of-interest(POI)data,clustering hotspots of high-dimensional restaurant data were identified.A hierarchical network of restaurant hotspots was constructed following the Central Place Theory(CPT)framework,while the Geo-Informatic Tupu method was employed to resolve the challenges posed by network deformation in multi-scale processes.These findings suggest the necessity of enhancing the spatial balance of Shanghai’s urban centers by moderately increasing the number and service capacity of suburban centers at the urban periphery.Such measures would contribute to a more optimized urban structure and facilitate the outward dispersion of comfort-oriented facilities such as the restaurant industry.At a finer spatial scale,the distribution of restaurant hotspots demonstrates a polycentric and symmetric spatial pattern,with a developmental trend radiating outward along the city’s ring roads.This trend can be attributed to the efforts of restaurants to establish connections with other urban functional spaces,leading to the reconfiguration of urban spaces,expansion of restaurant-dedicated land use,and the reorganization of associated commercial activities.The results validate the existence of a polycentric urban structure in Shanghai but also highlight the instability of the restaurant hotspot network during cross-scale transitions.
基金Sponsored by Beijing Youth Innovation Talent Support Program for Urban Greening and Landscaping——The 2024 Special Project for Promoting High-Quality Development of Beijing’s Landscaping through Scientific and Technological Innovation(KJCXQT202410).
文摘Taking the Ming Tombs Forest Farm in Beijing as the research object,this research applied multi-source data fusion and GIS heat-map overlay analysis techniques,systematically collected bird observation point data from the Global Biodiversity Information Facility(GBIF),population distribution data from the Oak Ridge National Laboratory(ORNL)in the United States,as well as information on the composition of tree species in suitable forest areas for birds and the forest geographical information of the Ming Tombs Forest Farm,which is based on literature research and field investigations.By using GIS technology,spatial processing was carried out on bird observation points and population distribution data to identify suitable bird-watching areas in different seasons.Then,according to the suitability value range,these areas were classified into different grades(from unsuitable to highly suitable).The research findings indicated that there was significant spatial heterogeneity in the bird-watching suitability of the Ming Tombs Forest Farm.The north side of the reservoir was generally a core area with high suitability in all seasons.The deep-aged broad-leaved mixed forests supported the overlapping co-existence of the ecological niches of various bird species,such as the Zosterops simplex and Urocissa erythrorhyncha.In contrast,the shallow forest-edge coniferous pure forests and mixed forests were more suitable for specialized species like Carduelis sinica.The southern urban area and the core area of the mausoleums had relatively low suitability due to ecological fragmentation or human interference.Based on these results,this paper proposed a three-level protection framework of“core area conservation—buffer zone management—isolation zone construction”and a spatio-temporal coordinated human-bird co-existence strategy.It was also suggested that the human-bird co-existence space could be optimized through measures such as constructing sound and light buffer interfaces,restoring ecological corridors,and integrating cultural heritage elements.This research provided an operational technical approach and decision-making support for the scientific planning of bird-watching sites and the coordination of ecological protection and tourism development.
基金supported by the National Natural Science Foundation of China(Grant Nos.U22A20598 and 52104107)the"Qinglan Project"of Jiangsu Colleges and Universities,Young Elite Scientists Sponsorship Program of Jiangsu Province(Grant No.TJ-2023-086).
文摘As coal mining progresses to greater depths,controlling the stability of surrounding rock in deep roadways has become an increasingly complex challenge.Although four-dimensional(4D)support theoretically offers unique advantages in maintaining the stability of rock mass,the disaster evolution processes and multi-source information response characteristics in deep roadways with 4D support remain unclear.Consequently,a large-scale physical model testing system and self-designed 4D support components were employed to conduct similarity model tests on the surrounding rock failure process under unsupported(U-1),traditional bolt-mesh-cable support(T-2),and 4D support(4D-R-3)conditions.Combined with multi-source monitoring techniques,including stress–strain,digital image correlation(DIC),acoustic emission(AE),microseismic(MS),parallel electric(PE),and electromagnetic radiation(EMR),the mechanical behavior and multi-source information responses were comprehensively analyzed.The results show that the peak stress and displacement of the models are positively correlated with the support strength.The multi-source information exhibits distinct response characteristics under different supports.The response frequency,energy,and fluctuationsof AE,MS,and EMR signals,along with the apparent resistivity(AR)high-resistivity zone,follow the trend U-1>T-2>4D-R-3.Furthermore,multi-source information exhibits significantdifferences in sensitivity across different phases.The AE,MS,and EMR signals exhibit active responses to rock mass activity at each phase.However,AR signals are only sensitive to the fracture propagation during the plastic yield and failure phases.In summary,the 4D support significantlyenhances the bearing capacity and plastic deformation of the models,while substantially reducing the frequency,energy,and fluctuationsof multi-source signals.
文摘Vector transducer can simultaneously measure components of particle velocity as well as pressure at some point in sound field. In this paper, a series of equations are obtained from the correlation of particle velocity and pressure of the incident wave field, the error of each equation with white noise is studied, and Differential Evolution is used in solving the equations to distinguish multi-sources. Results of computer simulation show that Differential Evolution has more superiority than Genetic Algorithms on the rate and precision of convergence under the same condition.
基金supported by the Gansu Provincial Natural Science Foundation(grant number 25JRRA074)the Gansu Provincial Key R&D Science and Technology Program(grant number 24YFGA060)the National Natural Science Foundation of China(grant number 62161019).
文摘Modern intelligent systems,such as autonomous vehicles and face recognition,must continuously adapt to new scenarios while preserving their ability to handle previously encountered situations.However,when neural networks learn new classes sequentially,they suffer from catastrophic forgetting—the tendency to lose knowledge of earlier classes.This challenge,which lies at the core of class-incremental learning,severely limits the deployment of continual learning systems in real-world applications with streaming data.Existing approaches,including rehearsalbased methods and knowledge distillation techniques,have attempted to address this issue but often struggle to effectively preserve decision boundaries and discriminative features under limited memory constraints.To overcome these limitations,we propose a support vector-guided framework for class-incremental learning.The framework integrates an enhanced feature extractor with a Support Vector Machine classifier,which generates boundary-critical support vectors to guide both replay and distillation.Building on this architecture,we design a joint feature retention strategy that combines boundary proximity with feature diversity,and a Support Vector Distillation Loss that enforces dual alignment in decision and semantic spaces.In addition,triple attention modules are incorporated into the feature extractor to enhance representation power.Extensive experiments on CIFAR-100 and Tiny-ImageNet demonstrate effective improvements.On CIFAR-100 and Tiny-ImageNet with 5 tasks,our method achieves 71.68%and 58.61%average accuracy,outperforming strong baselines by 3.34%and 2.05%.These advantages are consistently observed across different task splits,highlighting the robustness and generalization of the proposed approach.Beyond benchmark evaluations,the framework also shows potential in few-shot and resource-constrained applications such as edge computing and mobile robotics.
基金supported by grants PID2020-120308RB-I00 and PID2023-147802OB-I00 funded by MICIU/AEI/10.13039/501100011033FEDER,UE,by Aligning Science Across Parkinson’s(ref.ASAP-020505)through the Michael J.Fox Foundation for Parkinson’s Research+1 种基金by CiberNed Intramural Collaborative Projects(ref.PI2020/09)by the Spanish Fundación Mutua Madrile?a de Investigación Médica(to JLL)。
文摘The development of clinical candidates that modify the natural progression of sporadic Parkinson's disease and related synucleinopathies is a praiseworthy endeavor,but extremely challenging.Therapeutic candidates that were successful in preclinical Parkinson's disease animal models have repeatedly failed when tested in clinical trials.While these failures have many possible explanations,it is perhaps time to recognize that the problem lies with the animal models rather than the putative candidate.In other words,the lack of adequate animal models of Parkinson's disease currently represents the main barrier to preclinical identification of potential disease-modifying therapies likely to succeed in clinical trials.However,this barrier may be overcome by the recent introduction of novel generations of viral vectors coding for different forms of alpha-synuclein species and related genes.Although still facing several limitations,these models have managed to mimic the known neuropathological hallmarks of Parkinson's disease with unprecedented accuracy,delineating a more optimistic scenario for the near future.
文摘Fluidic Thrust Vectoring(FTV)is used for the yaw attitude control of tailless flying wing,which can significantly improve stealth performance,maneuverability and lateral/heading maneuverability.The FTV control scheme of co-directional secondary flow was designed based on a 30 kgf thrust turbojet engine,an equivalent rudder deflection control variable of Mass Flow Combination(MFC)was proposed,and a control model was established to form a FTV control system scheme,which was integrated with the flight control system of a 100 kg tailless flying wing with medium aspect ratio to achieve closed-loop control of the yaw attitude based on FTV.The heading stability augmentation and maneuvering control characteristics and time response characteristics of tailless flying wing by FTV were quantitatively studied through virtual flight test in a wind tunnel at a wind speed of 35 m/s.The results show that the control strategy based on MFC achieves bidirectional continuous and stable control of thrust vector angle in a range of±11°,and the thrust vector angle varies monotonically with MFC;the co-directional FTV realizes bidirectional continuous and stable control of the yaw attitude of tailless flying wing,without longitudinal/lateral coupling moment.The increment of the maximum yawing moment coefficient is 0.0029,the maximum yaw rate is 7.55(°)/s,and the response time of the yaw rate of the vectoring nozzle actuated by the secondary flow is about 0.06 s,which satisfies the heading stability augmentation and maneuvering control response requirements of the aircraft with statically unstable heading,and provides new control means for the heading rudderless attitude control of tailless flying wing.