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Oncogenic Ras,Yki and Notch signals converge to confer clone competitiveness through Upd2
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作者 Ying Wang Rui Huang +6 位作者 Minfeng Deng Jingjing He Mingxi Deng Toyotaka Ishibashi Cong Yu Zongzhao Zhai Yan Yan 《Journal of Genetics and Genomics》 2026年第1期110-120,共11页
Cell competition is an evolutionarily ancient mechanism that functions to remove unfit or dangerous clonal cells in a multicellular community.A classical model is the removal of polarity-deficient clones,such as the p... Cell competition is an evolutionarily ancient mechanism that functions to remove unfit or dangerous clonal cells in a multicellular community.A classical model is the removal of polarity-deficient clones,such as the precancerous scribble(scrib)mutant clones,in Drosophila imaginal discs.The activation of Ras,Yki,or Notch signaling robustly reverses the scrib mutant clonal fate from elimination to tumorous growth.Whether these signals converge to adopt a common mechanism to overcome the elimination pressure posed by cell competition remains unclear.Using single-cell transcriptomics,we find that a critical converging point downstream of Ras,Yki,and Notch signals is the upregulation of Upd2,an IL-6 family cytokine.Overexpression of Upd2 is sufficient to rescue the scrib mutant clones from elimination.Depletion of Upd2 blocks the growth of the scrib mutant clones with active Ras,Yki,and Notch signals.Moreover,Upd2 overexpression promotes robust intestinal stem cell(ISC)proliferation,while Upd2 is intrinsically required in ISCs for the growth of the adult intestine.Together,these results identify Upd2 as a crucial cell fitness factor that sustains tissue growth but can potentiate tumorigenesis when deregulated. 展开更多
关键词 Drosophila melanogaster Cell competition Single-cell transcriptomics Notch signaling Ras signaling Hippo signaling
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A review on research of system dynamics and multi-source fault diagnosis of key components in high-speed train
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作者 Baosen Wang Yongqiang Liu +4 位作者 Qilan Li Min Wang Qiaoying Ma Yingying Liao Shaopu Yang 《Chinese Journal of Mechanical Engineering》 2026年第1期496-507,共12页
As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-... As China's high-speed railway technology advances,high-speed trains have emerged as a pivotal mode of transportation,instrumental in facilitating passenger and freight mobility while fostering robust regional eco-nomic and trade interactions.Nonetheless,the safety of train operations remains a paramount concern,prompting extensive research into the dynamic behavior of critical components,which is essential to ensuring seamless and secure transportation services.This article commences by comprehensively reviewing the current landscape and evolutionary trajectory of dynamic model analysis for both traditional bearings and axle box bearings.Emphasis is placed on elucidating the profound influence of diverse bearing fault types on the system's kinematic state,alongside delving into the research methodologies employed in developing multi-physics field coupling models.Subsequently,it expounds on the content of investigations focusing on various wheel and track impairments,grounded in the dynamic modeling of the bearing vehicle coupling system.Concurrently,the intricate interplay between wheel-rail excitation and axle box bearing faults on the system's performance is elucidated.Concludingly,the article underscores the inadequacy of current multi-source fault diagnosis meth-odologies in tackling the intricacies of complex train operating environments,thereby highlighting its sig-nificance as a pressing and vital research agenda for the future. 展开更多
关键词 High-speed train Axle box bearing Dynamic model Wheel rail excitation multi-source fault
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Drive-by spatial offset detection for high-speed railway bridges based on fusion analysis of multi-source data from comprehensive inspection train
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作者 Chuang Wang Jiawang Zhan +4 位作者 Nan Zhang Yujie Wang Xinxiang Xu Zhihang Wang Zhen Ni 《Railway Engineering Science》 2026年第1期128-148,共21页
The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR ... The spatial offset of bridge has a significant impact on the safety,comfort,and durability of high-speed railway(HSR)operations,so it is crucial to rapidly and effectively detect the spatial offset of operational HSR bridges.Drive-by monitoring of bridge uneven settlement demonstrates significant potential due to its practicality,cost-effectiveness,and efficiency.However,existing drive-by methods for detecting bridge offset have limitations such as reliance on a single data source,low detection accuracy,and the inability to identify lateral deformations of bridges.This paper proposes a novel drive-by inspection method for spatial offset of HSR bridge based on multi-source data fusion of comprehensive inspection train.Firstly,dung beetle optimizer-variational mode decomposition was employed to achieve adaptive decomposition of non-stationary dynamic signals,and explore the hidden temporal relationships in the data.Subsequently,a long short-term memory neural network was developed to achieve feature fusion of multi-source signal and accurate prediction of spatial settlement of HSR bridge.A dataset of track irregularities and CRH380A high-speed train responses was generated using a 3D train-track-bridge interaction model,and the accuracy and effectiveness of the proposed hybrid deep learning model were numerically validated.Finally,the reliability of the proposed drive-by inspection method was further validated by analyzing the actual measurement data obtained from comprehensive inspection train.The research findings indicate that the proposed approach enables rapid and accurate detection of spatial offset in HSR bridge,ensuring the long-term operational safety of HSR bridges. 展开更多
关键词 High-speed railway bridge Drive-by inspection Spatial offset multi-source data fusion Deep learning
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EDTM:Efficient Domain Transition for Multi-Source Domain Adaptation
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作者 Mangyu Lee Jaekyun Jeong +2 位作者 Yun Wook Choo Keejun Han Jungeun Kim 《Computer Modeling in Engineering & Sciences》 2026年第2期955-970,共16页
Domain adaptation aims to reduce the distribution gap between the training data(source domain)and the target data.This enables effective predictions even for domains not seen during training.However,most conventional ... Domain adaptation aims to reduce the distribution gap between the training data(source domain)and the target data.This enables effective predictions even for domains not seen during training.However,most conventional domain adaptation methods assume a single source domain,making them less suitable for modern deep learning settings that rely on diverse and large-scale datasets.To address this limitation,recent research has focused on Multi-Source Domain Adaptation(MSDA),which aims to learn effectively from multiple source domains.In this paper,we propose Efficient Domain Transition for Multi-source(EDTM),a novel and efficient framework designed to tackle two major challenges in existing MSDA approaches:(1)integrating knowledge across different source domains and(2)aligning label distributions between source and target domains.EDTM leverages an ensemble-based classifier expert mechanism to enhance the contribution of source domains that are more similar to the target domain.To further stabilize the learning process and improve performance,we incorporate imitation learning into the training of the target model.In addition,Maximum Classifier Discrepancy(MCD)is employed to align class-wise label distributions between the source and target domains.Experiments were conducted using Digits-Five,one of the most representative benchmark datasets for MSDA.The results show that EDTM consistently outperforms existing methods in terms of average classification accuracy.Notably,EDTM achieved significantly higher performance on target domains such as Modified National Institute of Standards and Technolog with blended background images(MNIST-M)and Street View House Numbers(SVHN)datasets,demonstrating enhanced generalization compared to baseline approaches.Furthermore,an ablation study analyzing the contribution of each loss component validated the effectiveness of the framework,highlighting the importance of each module in achieving optimal performance. 展开更多
关键词 multi-source domain adaptation imitation learning maximum classifier discrepancy ensemble based classifier EDTM
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A CNN-Transformer Hybrid Model for Real-Time Recognition of Affective Tactile Biosignals
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作者 Chang Xu Xianbo Yin +1 位作者 Zhiyong Zhou Bomin Liu 《Computers, Materials & Continua》 2026年第4期2343-2356,共14页
This study presents a hybrid CNN-Transformer model for real-time recognition of affective tactile biosignals.The proposed framework combines convolutional neural networks(CNNs)to extract spatial and local temporal fea... This study presents a hybrid CNN-Transformer model for real-time recognition of affective tactile biosignals.The proposed framework combines convolutional neural networks(CNNs)to extract spatial and local temporal features with the Transformer encoder that captures long-range dependencies in time-series data through multi-head attention.Model performance was evaluated on two widely used tactile biosignal datasets,HAART and CoST,which contain diverse affective touch gestures recorded from pressure sensor arrays.TheCNN-Transformer model achieved recognition rates of 93.33%on HAART and 80.89%on CoST,outperforming existing methods on both benchmarks.By incorporating temporal windowing,the model enables instantaneous prediction,improving generalization across gestures of varying duration.These results highlight the effectiveness of deep learning for tactile biosignal processing and demonstrate the potential of theCNN-Transformer approach for future applications in wearable sensors,affective computing,and biomedical monitoring. 展开更多
关键词 Tactile biosignals affective touch recognition wearable sensors signal processing human-machine interaction
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High-precision classification of benthic habitat sediments in shallow waters of islands by multi-source data
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作者 Qiuhua TANG Ningning LI +4 位作者 Yujie ZHANG Zhipeng DONG Yongling ZHENG Jingjing BAO Jingyu ZHANG 《Journal of Oceanology and Limnology》 2026年第1期99-108,共10页
Benthic habitat mapping is an emerging discipline in the international marine field in recent years,providing an effective tool for marine spatial planning,marine ecological management,and decision-making applications... Benthic habitat mapping is an emerging discipline in the international marine field in recent years,providing an effective tool for marine spatial planning,marine ecological management,and decision-making applications.Seabed sediment classification is one of the main contents of seabed habitat mapping.In response to the impact of remote sensing imaging quality and the limitations of acoustic measurement range,where a single data source does not fully reflect the substrate type,we proposed a high-precision seabed habitat sediment classification method that integrates data from multiple sources.Based on WorldView-2 multi-spectral remote sensing image data and multibeam bathymetry data,constructed a random forests(RF)classifier with optimal feature selection.A seabed sediment classification experiment integrating optical remote sensing and acoustic remote sensing data was carried out in the shallow water area of Wuzhizhou Island,Hainan,South China.Different seabed sediment types,such as sand,seagrass,and coral reefs were effectively identified,with an overall classification accuracy of 92%.Experimental results show that RF matrix optimized by fusing multi-source remote sensing data for feature selection were better than the classification results of simple combinations of data sources,which improved the accuracy of seabed sediment classification.Therefore,the method proposed in this paper can be effectively applied to high-precision seabed sediment classification and habitat mapping around islands and reefs. 展开更多
关键词 Wuzhizhou Island marine remote sensing coastal mapping multi-spectral remote sensing shallow water reef seabed sediment classification benthic habitat mapping multi-source data fusion random forest(RF)
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Fatigue Detection with Multimodal Physiological Signals via Uncertainty-Aware Deep Transfer Learning
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作者 Kourosh Kakhi Hamzeh Asgharnezhad +2 位作者 Abbas Khosravi Roohallah Alizadehsani U.Rajendra Acharya 《Journal of Bionic Engineering》 2026年第1期472-487,共16页
Accurate detection of driver fatigue is essential for improving road safety.This study investigates the effectiveness of using multimodal physiological signals for fatigue detection while incorporating uncertainty qua... Accurate detection of driver fatigue is essential for improving road safety.This study investigates the effectiveness of using multimodal physiological signals for fatigue detection while incorporating uncertainty quantification to enhance the reliability of predictions.Physiological signals,including Electrocardiogram(ECG),Galvanic Skin Response(GSR),and Electroencephalogram(EEG),were transformed into image representations and analyzed using pretrained deep neu-ral networks.The extracted features were classified through a feedforward neural network,and prediction reliability was assessed using uncertainty quantification techniques such as Monte Carlo Dropout(MCD),model ensembles,and combined approaches.Evaluation metrics included standard measures(sensitivity,specificity,precision,and accuracy)along with uncertainty-aware metrics such as uncertainty sensitivity and uncertainty precision.Across all evaluations,ECG-based models consistently demonstrated strong performance.The findings indicate that combining multimodal physi-ological signals,Transfer Learning(TL),and uncertainty quantification can significantly improve both the accuracy and trustworthiness of fatigue detection systems.This approach supports the development of more reliable driver assistance technologies aimed at preventing fatigue-related accidents. 展开更多
关键词 Fatigue detection Multimodal physiological signals Deep transfer learning Uncertainty-aware learning Driver monitoring
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New Method of Multi-Source Heterogeneous Data Signal Processing of Power Internet of Things Based on Compressive Sensing
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作者 Li Yongjie Shen Jing +3 位作者 Zang Huaping Hou Huanpeng Yang Yimu Yao Haoyu 《China Communications》 2025年第11期242-255,共14页
In the heterogeneous power internet of things(IoT)environment,data signals are acquired to support different business systems to realize advanced intelligent applications,with massive,multi-source,heterogeneous and ot... In the heterogeneous power internet of things(IoT)environment,data signals are acquired to support different business systems to realize advanced intelligent applications,with massive,multi-source,heterogeneous and other characteristics.Reliable perception of information and efficient transmission of energy in multi-source heterogeneous environments are crucial issues.Compressive sensing(CS),as an effective method of signal compression and transmission,can accurately recover the original signal only by very few sampling.In this paper,we study a new method of multi-source heterogeneous data signal reconstruction of power IoT based on compressive sensing technology.Based on the traditional compressive sensing technology to directly recover multi-source heterogeneous signals,we fully use the interference subspace information to design the measurement matrix,which directly and effectively eliminates the interference while making the measurement.The measure matrix is optimized by minimizing the average cross-coherence of the matrix,and the reconstruction performance of the new method is further improved.Finally,the effectiveness of the new method with different parameter settings under different multi-source heterogeneous data signal cases is verified by using orthogonal matching pursuit(OMP)and sparsity adaptive matching pursuit(SAMP)for considering the actual environment with prior information utilization of signal sparsity and no prior information utilization of signal sparsity. 展开更多
关键词 compressive sensing heterogeneous power internet of things multi-source heterogeneous signal reconstruction
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Cycle-by-Cycle Queue Length Estimation for Signalized Intersections Using Multi-Source Data 被引量:4
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作者 Zhongyu Wang Qing Cai +2 位作者 Bing Wu Yinhai Wang Linbo Li 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2015年第2期86-93,共8页
In order to estimate vehicular queue length at signalized intersections accurately and overcome the shortcomings and restrictions of existing studies especially those based on shockwave theory,a new methodology is pre... In order to estimate vehicular queue length at signalized intersections accurately and overcome the shortcomings and restrictions of existing studies especially those based on shockwave theory,a new methodology is presented for estimating vehicular queue length using data from both point detectors and probe vehicles. The methodology applies the shockwave theory to model queue evolution over time and space. Using probe vehicle locations and times as well as point detector measured traffic states,analytical formulations for calculating the maximum and minimum( residual) queue length are developed. The proposed methodology is verified using ground truth data collected from numerical experiments conducted in Shanghai,China. It is found that the methodology has a mean absolute percentage error of 17. 09%,which is reasonably effective in estimating the queue length at traffic signalized intersections. Limitations of the proposed models and algorithms are also discussed in the paper. 展开更多
关键词 QUEUE LENGTH estimation multi-source data TRAFFIC signals TRAFFIC SHOCKWAVE theory
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Time-frequency Feature Extraction Method of the Multi-Source Shock Signal Based on Improved VMD and Bilateral Adaptive Laplace Wavelet 被引量:5
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作者 Nanyang Zhao Jinjie Zhang +2 位作者 Zhiwei Mao Zhinong Jiang He Li 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第2期166-179,共14页
Vibration signals have the characteristics of multi-source strong shock coupling and strong noise interference owing to the complex structure of reciprocating machinery.Therefore,it is difficult to extract,analyze,and... Vibration signals have the characteristics of multi-source strong shock coupling and strong noise interference owing to the complex structure of reciprocating machinery.Therefore,it is difficult to extract,analyze,and diagnose mechanical fault features.To accurately extract sensitive features from the strong noise interference and unsteady monitoring signals of reciprocating machinery,a study on the time-frequency feature extraction method of multi-source shock signals is conducted.Combining the characteristics of reciprocating mechanical vibration signals,a targeted optimization method considering the variational modal decomposition(VMD)mode number and second penalty factor is proposed,which completed the adaptive decomposition of coupled signals.Aiming at the bilateral asymmetric attenuation characteristics of reciprocating mechanical shock signals,a new bilateral adaptive Laplace wavelet(BALW)is established.A search strategy for wavelet local parameters of multi-shock signals is proposed using the harmony search(HS)method.A multi-source shock simulation signal is established,and actual data on the valve fault are obtained through diesel engine fault experiments.The fault recognition rate of the intake and exhaust valve clearance is above 90%and the extraction accuracy of the shock start position is improved by 10°. 展开更多
关键词 Shock signal processing WAVELET VMD Fault diagnosis Diesel engine
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Dynamics of inflammatory signals within the tumor microenvironment 被引量:1
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作者 Hala Issa Lokjan Singh +2 位作者 Kok-Song Lai Tina Parusheva-Borsitzky Shamshul Ansari 《World Journal of Experimental Medicine》 2025年第2期24-39,共16页
Tumor stroma,or tumor microenvironment(TME),has been in the spotlight during recent years for its role in tumor development,growth,and metastasis.It consists of a myriad of elements,including tumor-associated macropha... Tumor stroma,or tumor microenvironment(TME),has been in the spotlight during recent years for its role in tumor development,growth,and metastasis.It consists of a myriad of elements,including tumor-associated macrophages,cancer-associated fibroblasts,a deregulated extracellular matrix,endothelial cells,and vascular vessels.The release of proinflammatory molecules,due to the inflamed microenvironment,such as cytokines and chemokines is found to play a pivotal role in progression of cancer and response to therapy.This review discusses the major key players and important chemical inflammatory signals released in the TME.Furthermore,the latest breakthroughs in cytokine-mediated crosstalk between immune cells and cancer cells have been highlighted.In addition,recent updates on alterations in cytokine signaling between chronic inflammation and malignant TME have also been reviewed. 展开更多
关键词 Inflammatory signals Tumor microenvironment CYTOKINES INTERLEUKINS Transforming growth factor
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Understory terrain estimation using multi-source remote sensing data under different forest-type conditions
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作者 HUANG Jia-Peng FAN Qing-Nan ZHANG Yue 《红外与毫米波学报》 北大核心 2025年第6期919-932,共14页
Accurate estimation of understory terrain has significant scientific importance for maintaining ecosystem balance and biodiversity conservation.Addressing the issue of inadequate representation of spatial heterogeneit... Accurate estimation of understory terrain has significant scientific importance for maintaining ecosystem balance and biodiversity conservation.Addressing the issue of inadequate representation of spatial heterogeneity when traditional forest topographic inversion methods consider the entire forest as the inversion unit,this study pro⁃poses a differentiated modeling approach to forest types based on refined land cover classification.Taking Puerto Ri⁃co and Maryland as study areas,a multi-dimensional feature system is constructed by integrating multi-source re⁃mote sensing data:ICESat-2 spaceborne LiDAR is used to obtain benchmark values for understory terrain,topo⁃graphic factors such as slope and aspect are extracted based on SRTM data,and vegetation cover characteristics are analyzed using Landsat-8 multispectral imagery.This study incorporates forest type as a classification modeling con⁃dition and applies the random forest algorithm to build differentiated topographic inversion models.Experimental re⁃sults indicate that,compared to traditional whole-area modeling methods(RMSE=5.06 m),forest type-based classi⁃fication modeling significantly improves the accuracy of understory terrain estimation(RMSE=2.94 m),validating the effectiveness of spatial heterogeneity modeling.Further sensitivity analysis reveals that canopy structure parame⁃ters(with RMSE variation reaching 4.11 m)exert a stronger regulatory effect on estimation accuracy compared to forest cover,providing important theoretical support for optimizing remote sensing models of forest topography. 展开更多
关键词 understory terrain forest type multi-source remote sensing data random forest model
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Fracturing mechanism of pre-damaged granite induced by multi-source dynamic disturbances in tunnels
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作者 Biao Wang Benguo He +1 位作者 Xiating Feng Hongpu Li 《International Journal of Mining Science and Technology》 2025年第9期1439-1459,共21页
To elucidate the fracturing mechanism of deep hard rock under complex disturbance environments,this study investigates the dynamic failure behavior of pre-damaged granite subjected to multi-source dynamic disturbances... To elucidate the fracturing mechanism of deep hard rock under complex disturbance environments,this study investigates the dynamic failure behavior of pre-damaged granite subjected to multi-source dynamic disturbances.Blasting vibration monitoring was conducted in a deep-buried drill-and-blast tunnel to characterize in-situ dynamic loading conditions.Subsequently,true triaxial compression tests incorporating multi-source disturbances were performed using a self-developed wide-low-frequency true triaxial system to simulate disturbance accumulation and damage evolution in granite.The results demonstrate that combined dynamic disturbances and unloading damage significantly accelerate strength degradation and trigger shear-slip failure along preferentially oriented blast-induced fractures,with strength reductions up to 16.7%.Layered failure was observed on the free surface of pre-damaged granite under biaxial loading,indicating a disturbance-induced fracture localization mechanism.Time-stress-fracture-energy coupling fields were constructed to reveal the spatiotemporal characteristics of fracture evolution.Critical precursor frequency bands(105-150,185-225,and 300-325 kHz)were identified,which serve as diagnostic signatures of impending failure.A dynamic instability mechanism driven by multi-source disturbance superposition and pre-damage evolution was established.Furthermore,a grouting-based wave-absorption control strategy was proposed to mitigate deep dynamic disasters by attenuating disturbance amplitude and reducing excitation frequency. 展开更多
关键词 multi-source dynamic disturbances Blasting vibration Deep-buried tunnel Acoustic emission Time-delayed rockburst
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A Review of Deep Learning for Biomedical Signals:Current Applications,Advancements,Future Prospects,Interpretation,and Challenges
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作者 Ali Mohammad Alqudah Zahra Moussavi 《Computers, Materials & Continua》 2025年第6期3753-3841,共89页
This reviewpresents a comprehensive technical analysis of deep learning(DL)methodologies in biomedical signal processing,focusing on architectural innovations,experimental validation,and evaluation frameworks.We syste... This reviewpresents a comprehensive technical analysis of deep learning(DL)methodologies in biomedical signal processing,focusing on architectural innovations,experimental validation,and evaluation frameworks.We systematically evaluate key deep learning architectures including convolutional neural networks(CNNs),recurrent neural networks(RNNs),transformer-based models,and hybrid systems across critical tasks such as arrhythmia classification,seizure detection,and anomaly segmentation.The study dissects preprocessing techniques(e.g.,wavelet denoising,spectral normalization)and feature extraction strategies(time-frequency analysis,attention mechanisms),demonstrating their impact on model accuracy,noise robustness,and computational efficiency.Experimental results underscore the superiority of deep learning over traditional methods,particularly in automated feature extraction,real-time processing,cross-modal generalization,and achieving up to a 15%increase in classification accuracy and enhanced noise resilience across electrocardiogram(ECG),electroencephalogram(EEG),and electromyogram(EMG)signals.Performance is rigorously benchmarked using precision,recall,F1-scores,area under the receiver operating characteristic curve(AUC-ROC),and computational complexitymetrics,providing a unified framework for comparing model efficacy.Thesurvey addresses persistent challenges:synthetic data generationmitigates limited training samples,interpretability tools(e.g.,Gradient-weighted Class Activation Mapping(Grad-CAM),Shapley values)resolve model opacity,and federated learning ensures privacy-compliant deployments.Distinguished from prior reviews,this work offers a structured taxonomy of deep learning architectures,integrates emerging paradigms like transformers and domain-specific attention mechanisms,and evaluates preprocessing pipelines for spectral-temporal trade-offs.It advances the field by bridging technical advancements with clinical needs,such as scalability in real-world settings(e.g.,wearable devices)and regulatory alignment with theHealth Insurance Portability and Accountability Act(HIPAA)and General Data Protection Regulation(GDPR).By synthesizing technical rigor,ethical considerations,and actionable guidelines for model selection,this survey establishes a holistic reference for developing robust,interpretable biomedical artificial intelligence(AI)systems,accelerating their translation into personalized and equitable healthcare solutions. 展开更多
关键词 Deep learning deep models biomedical signals physiological signals biosignals
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A fluorescence-enhanced inverse opal sensing film for multi-sources detection of formaldehyde
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作者 Xiaokang Lu Bo Han +6 位作者 Deyilei Wei Mingzhu Chu Haojie Ma Ran Li Xueyan Hou Yuqi Zhang Jijiang Wang 《Food Science and Human Wellness》 2025年第5期1818-1826,共9页
The SiO_(2) inverse opal photonic crystals(PC)with a three-dimensional macroporous structure were fabricated by the sacrificial template method,followed by infiltration of a pyrene derivative,1-(pyren-8-yl)but-3-en-1-... The SiO_(2) inverse opal photonic crystals(PC)with a three-dimensional macroporous structure were fabricated by the sacrificial template method,followed by infiltration of a pyrene derivative,1-(pyren-8-yl)but-3-en-1-amine(PEA),to achieve a formaldehyde(FA)-sensitive and fluorescence-enhanced sensing film.Utilizing the specific Aza-Cope rearrangement reaction of allylamine of PEA and FA to generate a strong fluorescent product emitted at approximately 480 nm,we chose a PC whose blue band edge of stopband overlapped with the fluorescence emission wavelength.In virtue of the fluorescence enhancement property derived from slow photon effect of PC,FA was detected highly selectively and sensitively.The limit of detection(LoD)was calculated to be 1.38 nmol/L.Furthermore,the fast detection of FA(within 1 min)is realized due to the interconnected three-dimensional macroporous structure of the inverse opal PC and its high specific surface area.The prepared sensing film can be used for the detection of FA in air,aquatic products and living cells.The very close FA content in indoor air to the result from FA detector,the recovery rate of 101.5%for detecting FA in aquatic products and fast fluorescence imaging in 2 min for living cells demonstrate the reliability and accuracy of our method in practical applications. 展开更多
关键词 Inverse opal photonic crystals Slow photon effect Fluorescence enhancement multi-sources detection FORMALDEHYDE
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MMH-FE:AMulti-Precision and Multi-Sourced Heterogeneous Privacy-Preserving Neural Network Training Based on Functional Encryption
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作者 Hao Li Kuan Shao +2 位作者 Xin Wang Mufeng Wang Zhenyong Zhang 《Computers, Materials & Continua》 2025年第3期5387-5405,共19页
Due to the development of cloud computing and machine learning,users can upload their data to the cloud for machine learning model training.However,dishonest clouds may infer user data,resulting in user data leakage.P... Due to the development of cloud computing and machine learning,users can upload their data to the cloud for machine learning model training.However,dishonest clouds may infer user data,resulting in user data leakage.Previous schemes have achieved secure outsourced computing,but they suffer from low computational accuracy,difficult-to-handle heterogeneous distribution of data from multiple sources,and high computational cost,which result in extremely poor user experience and expensive cloud computing costs.To address the above problems,we propose amulti-precision,multi-sourced,andmulti-key outsourcing neural network training scheme.Firstly,we design a multi-precision functional encryption computation based on Euclidean division.Second,we design the outsourcing model training algorithm based on a multi-precision functional encryption with multi-sourced heterogeneity.Finally,we conduct experiments on three datasets.The results indicate that our framework achieves an accuracy improvement of 6%to 30%.Additionally,it offers a memory space optimization of 1.0×2^(24) times compared to the previous best approach. 展开更多
关键词 Functional encryption multi-sourced heterogeneous data privacy preservation neural networks
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RBOHD,GLR3.3,and GLR3.6 cooperatively control wounding hypocotyl-induced systemic Ca^(2+) signals,jasmonic acid,and glucosinolates in Arabidopsis leaves
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作者 Che Zhan Na Xue +2 位作者 Zhongxiang Tianyin Zheng Jianqiang Wu 《Plant Diversity》 2025年第4期690-701,共12页
Ca^(2+)signaling plays crucial roles in plant stress responses,including defense against insects.To counteract insect feeding,different parts of a plant deploy systemic signaling to communicate and coordinate defense ... Ca^(2+)signaling plays crucial roles in plant stress responses,including defense against insects.To counteract insect feeding,different parts of a plant deploy systemic signaling to communicate and coordinate defense responses,but little is known about the underlying mechanisms.In this study,micrografting,in vivo imaging of Ca^(2+)and reactive oxygen species(ROS),quantification of jasmonic acid(JA)and defensive metabolites,and bioassay were used to study how Arabidopsis seedlings regulate systemic responses in leaves after hypocotyls are wounded.We show that wounding hypocotyls rapidly activated both Ca^(2+)and ROS signals in leaves.RBOHD,which functions to produce ROS,along with two glutamate receptors GLR3.3 and GLR3.6,but not individually RBOHD or GLR3.3 and GLR3.6,in hypocotyls regulate the dynamics of systemic Ca^(2+)signals in leaves.In line with the systemic Ca^(2+)signals,after wounding hypocotyl,RBOHD,GLR3.3,and GLR3.6 in hypocotyl also cooperatively regulate the transcriptome,hormone jasmonic acid,and defensive secondary metabolites in leaves of Arabidopsis seedlings,thus controlling the systemic resistance to insects.Unlike leaf-to-leaf systemic signaling,this study reveals the unique regulation of wounding-induced hypocotyl-to-leaf systemic signaling and sheds new light on how different plant organs use complex signaling pathways to modulate defense responses. 展开更多
关键词 signal transduction GRAFTING Reactive oxygen species Calcium signaling GLUTAMATE Jasmonic acid
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Memory-Fused Dual-Stream Fault Diagnosis Network Based on Transformer Vibration Signals
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作者 Mingxing Wu Chengzhen Li +5 位作者 Xinyan Feng Fei Chen Yingchun Feng Huihui Song Wenyu Wang Faye Zhang 《Structural Durability & Health Monitoring》 2025年第6期1473-1487,共15页
As a core component of power systems, the operational status of transformers directly affects grid stability. To address the problem of “domain shift” in cross-domain fault diagnosis, this paper proposes a memory-en... As a core component of power systems, the operational status of transformers directly affects grid stability. To address the problem of “domain shift” in cross-domain fault diagnosis, this paper proposes a memory-enhanced dual-stream network (MemFuse-DSN). The method reconstructs the feature space by selecting and enhancing multi-source domain samples based on similarity metrics. An adaptive weighted dual-stream architecture is designed, integrating gradient reversal and orthogonality constraints to achieve efficient feature alignment. In addition, a novel dual dynamic memory module is introduced: the task memory bank is used to store high-confidence class prototype information, and adopts an exponential moving average (EMA) strategy to ensure the smooth evolution of prototypes over time;the domain memory bank is periodically updated and clusters potential noisy features, dynamically tracking domain shift trends, thereby optimizing the decoupled feature learning process. Experimental validation was conducted on a ±110 kV transformer vibration testing platform using typical fault types including winding looseness, core looseness, and compound faults. The results show that the proposed method achieves a fault diagnosis accuracy of 99.2%, providing a highly generalizable solution for the intelligent operation and maintenance of power equipment. 展开更多
关键词 Power transformer partial domain multi-source domain intelligent fault diagnosis
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A Method for Detecting Non-Cooperative Communication Signals Utilizing Multi-Resolution Time-Frequency Images
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作者 Zhaoqi Zhang Chundong Qi Danping Yu 《Journal of Beijing Institute of Technology》 2025年第5期447-457,共11页
Non-cooperative communication detection is a key technology for locating radio interfer-ence sources and conducting reconnaissance on adversary radiation sources.To meet the require-ments of wide-area monitoring,a sin... Non-cooperative communication detection is a key technology for locating radio interfer-ence sources and conducting reconnaissance on adversary radiation sources.To meet the require-ments of wide-area monitoring,a single interception channel often contains mixed multi-source sig-nals and interference,resulting in generally low signal-to-noise ratio(SNR)of the received signals;meanwhile,improving detection quality urgently requires either high frequency resolution or high-time resolution,which poses severe challenges to detection techniques based on time-frequency rep-resentations(TFR).To address this issue,this paper proposes a fixed-frame-structure signal detec-tion algorithm that integrates image enhancement and multi-scale template matching:first,the Otsu-Sauvola hybrid thresholding algorithm is employed to enhance TFR features,suppress noise interference,and extract time-frequency parameters of potential target signals(such as bandwidth and occurrence time);then,by exploiting the inherent time-frequency characteristics of the fixed-frame structure,the signal is subjected to multi-scale transformation(with either high-frequency resolution or high-time resolution),and accurate detection is achieved through the corresponding multi-scale template matching.Experimental results demonstrate that under 0 dB SNR conditions,the proposed algorithm achieves a detection rate greater than 87%,representing a significant improvement over traditional methods. 展开更多
关键词 signal detection non-cooperative communication signal image enhancement time-fre-quency transformation
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Monitoring track irregularities using multi-source on-board measurement data
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作者 Qinglin Xie Fei Peng +4 位作者 Gongquan Tao Yu Ren Fangbo Liu Jizhong Yang Zefeng Wen 《Railway Engineering Science》 2025年第4期746-765,共20页
Accurate monitoring of track irregularities is very helpful to improving the vehicle operation quality and to formulating appropriate track maintenance strategies.Existing methods have the problem that they rely on co... Accurate monitoring of track irregularities is very helpful to improving the vehicle operation quality and to formulating appropriate track maintenance strategies.Existing methods have the problem that they rely on complex signal processing algorithms and lack multi-source data analysis.Driven by multi-source measurement data,including the axle box,the bogie frame and the carbody accelerations,this paper proposes a track irregularities monitoring network(TIMNet)based on deep learning methods.TIMNet uses the feature extraction capability of convolutional neural networks and the sequence map-ping capability of the long short-term memory model to explore the mapping relationship between vehicle accelerations and track irregularities.The particle swarm optimization algorithm is used to optimize the network parameters,so that both the vertical and lateral track irregularities can be accurately identified in the time and spatial domains.The effectiveness and superiority of the proposed TIMNet is analyzed under different simulation conditions using a vehicle dynamics model.Field tests are conducted to prove the availability of the proposed TIMNet in quantitatively monitoring vertical and lateral track irregularities.Furthermore,comparative tests show that the TIMNet has a better fitting degree and timeliness in monitoring track irregularities(vertical R2 of 0.91,lateral R2 of 0.84 and time cost of 10 ms),compared to other classical regression.The test also proves that the TIMNet has a better anti-interference ability than other regression models. 展开更多
关键词 Track irregularities Vehicle accelerations On-board monitoring multi-source data Deep learning
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