Installing internal bulkheads in a composite bucket foundation alters the rotational symmetry characteristic of a single-compartment bucket foundation,consequently influencing the stress distribution within the bucket...Installing internal bulkheads in a composite bucket foundation alters the rotational symmetry characteristic of a single-compartment bucket foundation,consequently influencing the stress distribution within the bucket and surrounding soil.During the seabed penetration of a spudcan from a jack-up wind turbine installation vessel,an angle may form between the spudcan’s axis and the axis of symmetry of the adjacent composite bucket foundation in the horizontal plane.Such a misalignment may affect load distribution and the non-uniform interaction between the foundation,soil,and spudcan,ultimately influencing the foundation’s stability.This study employs physical model tests to ascertain the trends in end resistance during spudcan penetration in sand,the extent of soil disturbance,and the backflow condition.The finite element coupled Eulerian-Lagrangian method is validated and utilized to determine the range of penetration angles that induce alterations in the maximum vertical displacement and tilt rate of the composite bucket foundation in sand.The differential contact stress distribution at the base of the bucket is analyzed,with qualitative criteria for sand backflow provided.Findings demonstrate that the maximum vertical displacement and tilt rate of the composite bucket foundation display a“wave-like”variation with the increasing spudcan penetration angle,peaking when the angle between the spudcan and bulkhead is the smallest.Stress distribution is predominantly concentrated at the base and apex of the bucket,becoming increasingly uneven as the penetration angle deviates from the foundation’s symmetry axis.The maximum stress gradually shifts to the junction of the bulkhead and bucket bottom on the side with the shortest net distance from the spudcan.Considering the in-place stability and stress state of the composite bucket foundation is therefore imperative,and particular attention should be paid to the foundation’s state when the angle between the spudcan and bulkhead is small.展开更多
Because of the challenge of compounding lightweight,high-strength Ti/Al alloys due to their considerable disparity in properties,Al 6063 as intermediate layer was proposed to fabricate TC4/Al 6063/Al 7075 three-layer ...Because of the challenge of compounding lightweight,high-strength Ti/Al alloys due to their considerable disparity in properties,Al 6063 as intermediate layer was proposed to fabricate TC4/Al 6063/Al 7075 three-layer composite plate by explosive welding.The microscopic properties of each bonding interface were elucidated through field emission scanning electron microscope and electron backscattered diffraction(EBSD).A methodology combining finite element method-smoothed particle hydrodynamics(FEM-SPH)and molecular dynamics(MD)was proposed for the analysis of the forming and evolution characteristics of explosive welding interfaces at multi-scale.The results demonstrate that the bonding interface morphologies of TC4/Al 6063 and Al 6063/Al 7075 exhibit a flat and wavy configuration,without discernible defects or cracks.The phenomenon of grain refinement is observed in the vicinity of the two bonding interfaces.Furthermore,the degree of plastic deformation of TC4 and Al 7075 is more pronounced than that of Al 6063 in the intermediate layer.The interface morphology characteristics obtained by FEM-SPH simulation exhibit a high degree of similarity to the experimental results.MD simulations reveal that the diffusion of interfacial elements predominantly occurs during the unloading phase,and the simulated thickness of interfacial diffusion aligns well with experimental outcomes.The introduction of intermediate layer in the explosive welding process can effectively produce high-quality titanium/aluminum alloy composite plates.Furthermore,this approach offers a multi-scale simulation strategy for the study of explosive welding bonding interfaces.展开更多
Improving the volumetric energy density of supercapacitors is essential for practical applications,which highly relies on the dense storage of ions in carbon-based electrodes.The functional units of carbon-based elect...Improving the volumetric energy density of supercapacitors is essential for practical applications,which highly relies on the dense storage of ions in carbon-based electrodes.The functional units of carbon-based electrode exhibit multi-scale structural characteristics including macroscopic electrode morphologies,mesoscopic microcrystals and pores,and microscopic defects and dopants in the carbon basal plane.Therefore,the ordered combination of multi-scale structures of carbon electrode is crucial for achieving dense energy storage and high volumetric performance by leveraging the functions of various scale structu re.Considering that previous reviews have focused more on the discussion of specific scale structu re of carbon electrodes,this review takes a multi-scale perspective in which recent progresses regarding the structureperformance relationship,underlying mechanism and directional design of carbon-based multi-scale structures including carbon morphology,pore structure,carbon basal plane micro-environment and electrode technology on dense energy storage and volumetric property of supercapacitors are systematically discussed.We analyzed in detail the effects of the morphology,pore,and micro-environment of carbon electrode materials on ion dense storage,summarized the specific effects of different scale structures on volumetric property and recent research progress,and proposed the mutual influence and trade-off relationship between various scale structures.In addition,the challenges and outlooks for improving the dense storage and volumetric performance of carbon-based supercapacitors are analyzed,which can provide feasible technical reference and guidance for the design and manufacture of dense carbon-based electrode materials.展开更多
Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to ...Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to the inability to effectively capture global information from images,CNNs can easily lead to loss of contours and textures in segmentation results.Notice that the transformer model can effectively capture the properties of long-range dependencies in the image,and furthermore,combining the CNN and the transformer can effectively extract local details and global contextual features of the image.Motivated by this,we propose a multi-branch and multi-scale attention network(M2ANet)for medical image segmentation,whose architecture consists of three components.Specifically,in the first component,we construct an adaptive multi-branch patch module for parallel extraction of image features to reduce information loss caused by downsampling.In the second component,we apply residual block to the well-known convolutional block attention module to enhance the network’s ability to recognize important features of images and alleviate the phenomenon of gradient vanishing.In the third component,we design a multi-scale feature fusion module,in which we adopt adaptive average pooling and position encoding to enhance contextual features,and then multi-head attention is introduced to further enrich feature representation.Finally,we validate the effectiveness and feasibility of the proposed M2ANet method through comparative experiments on four benchmark medical image segmentation datasets,particularly in the context of preserving contours and textures.展开更多
Prediction of production decline and evaluation of the adsorbed/free gas ratio are critical for determining the lifespan and production status of shale gas wells.Traditional production prediction methods have some sho...Prediction of production decline and evaluation of the adsorbed/free gas ratio are critical for determining the lifespan and production status of shale gas wells.Traditional production prediction methods have some shortcomings because of the low permeability and tightness of shale,complex gas flow behavior of multi-scale gas transport regions and multiple gas transport mechanism superpositions,and complex and variable production regimes of shale gas wells.Recent research has demonstrated the existence of a multi-stage isotope fractionation phenomenon during shale gas production,with the fractionation characteristics of each stage associated with the pore structure,gas in place(GIP),adsorption/desorption,and gas production process.This study presents a new approach for estimating shale gas well production and evaluating the adsorbed/free gas ratio throughout production using isotope fractionation techniques.A reservoir-scale carbon isotope fractionation(CIF)model applicable to the production process of shale gas wells was developed for the first time in this research.In contrast to the traditional model,this model improves production prediction accuracy by simultaneously fitting the gas production rate and δ^(13)C_(1) data and provides a new evaluation method of the adsorbed/free gas ratio during shale gas production.The results indicate that the diffusion and adsorption/desorption properties of rock,bottom-hole flowing pressure(BHP)of gas well,and multi-scale gas transport regions of the reservoir all affect isotope fractionation,with the diffusion and adsorption/desorption parameters of rock having the greatest effect on isotope fractionation being D∗/D,PL,VL,α,and others in that order.We effectively tested the universality of the four-stage isotope fractionation feature and revealed a unique isotope fractionation mechanism caused by the superimposed coupling of multi-scale gas transport regions during shale gas well production.Finally,we applied the established CIF model to a shale gas well in the Sichuan Basin,China,and calculated the estimated ultimate recovery(EUR)of the well to be 3.33×10^(8) m^(3);the adsorbed gas ratio during shale gas production was 1.65%,10.03%,and 23.44%in the first,fifth,and tenth years,respectively.The findings are significant for understanding the isotope fractionation mechanism during natural gas transport in complex systems and for formulating and optimizing unconventional natural gas development strategies.展开更多
AIM:To identify topographic determinants of the anterior chamber angle(ACA)in patients with keratoconus(KCN).METHODS:Four hundred and ten eyes of 294 patients with KCN were recruited for this study.First,complete ocul...AIM:To identify topographic determinants of the anterior chamber angle(ACA)in patients with keratoconus(KCN).METHODS:Four hundred and ten eyes of 294 patients with KCN were recruited for this study.First,complete ocular examinations were performed for all patients,including visual acuity measurement,refraction,and slit-lamp biomicroscopy.Then,all participants underwent corneal imaging by the Oculus Pentacam HR.RESULTS:The mean age of the participants was 32.40±8.52y(15-60y)and 69.5%of them were male.The mean ACA was 38.47°±5.75°(range:14.40°to 56.50°)in the whole sample,38.24°±6.00°in males,and 38.98°±5.11°in females(P=0.447).The mean ACA was significantly different among different groups of cone morphology,as patients with nipple cones showed the lowest mean ACA.Moreover,there were statistically significant differences in the mean ACA among different groups of cone locations,with patients having central cones exhibiting the lowest mean ACA(P<0.001).Anterior and posterior Q values were significantly,directly correlated with ACA(anterior Q:r=0.122,P=0.014,posterior Q:r=0.192,P<0.001).CONCLUSION:This study provides critical insights into the risk factors for ACA narrowing in KCN patients,which is essential for planning intraocular surgeries.Patients with nipple and central cones exhibited the most significant ACA narrowing.Additionally,more negative Q-values are associated with increased ACA narrowing,highlighting the need for targeted diagnostic and therapeutic strategies.展开更多
To improve the vertical axis wind turbine(VAWT)design,the angle of attack(AOA)and airfoil data must be treated correctly.The present paper develops a method for determining AOA on a VAWT based on computational fluid d...To improve the vertical axis wind turbine(VAWT)design,the angle of attack(AOA)and airfoil data must be treated correctly.The present paper develops a method for determining AOA on a VAWT based on computational fluid dynamics(CFD)analysis.First,a CFD analysis of a two-bladed VAWT equipped with a NACA 0012 airfoil is conducted.The thrust and power coefficients are validated through experiments.Second,the blade force and velocity data at monitoring points are collected.The AOA at different azimuth angles is determined by removing the blade self-induction at the monitoring point.Then,the lift and drag coefficients as a function of AOA are extracted.Results show that this method is independent of the monitoring points selection located at certain distance to the blades and the extracted dynamic stall hysteresis is more precise than the one with the“usual”method without considering the self-induction from bound vortices.展开更多
In recent years,gait-based emotion recognition has been widely applied in the field of computer vision.However,existing gait emotion recognition methods typically rely on complete human skeleton data,and their accurac...In recent years,gait-based emotion recognition has been widely applied in the field of computer vision.However,existing gait emotion recognition methods typically rely on complete human skeleton data,and their accuracy significantly declines when the data is occluded.To enhance the accuracy of gait emotion recognition under occlusion,this paper proposes a Multi-scale Suppression Graph ConvolutionalNetwork(MS-GCN).TheMS-GCN consists of three main components:Joint Interpolation Module(JI Moudle),Multi-scale Temporal Convolution Network(MS-TCN),and Suppression Graph Convolutional Network(SGCN).The JI Module completes the spatially occluded skeletal joints using the(K-Nearest Neighbors)KNN interpolation method.The MS-TCN employs convolutional kernels of various sizes to comprehensively capture the emotional information embedded in the gait,compensating for the temporal occlusion of gait information.The SGCN extracts more non-prominent human gait features by suppressing the extraction of key body part features,thereby reducing the negative impact of occlusion on emotion recognition results.The proposed method is evaluated on two comprehensive datasets:Emotion-Gait,containing 4227 real gaits from sources like BML,ICT-Pollick,and ELMD,and 1000 synthetic gaits generated using STEP-Gen technology,and ELMB,consisting of 3924 gaits,with 1835 labeled with emotions such as“Happy,”“Sad,”“Angry,”and“Neutral.”On the standard datasets Emotion-Gait and ELMB,the proposed method achieved accuracies of 0.900 and 0.896,respectively,attaining performance comparable to other state-ofthe-artmethods.Furthermore,on occlusion datasets,the proposedmethod significantly mitigates the performance degradation caused by occlusion compared to other methods,the accuracy is significantly higher than that of other methods.展开更多
Unsteady aerodynamic characteristics at high angles of attack are of great importance to the design and development of advanced fighter aircraft, which are characterized by post-stall maneuverability with multiple Deg...Unsteady aerodynamic characteristics at high angles of attack are of great importance to the design and development of advanced fighter aircraft, which are characterized by post-stall maneuverability with multiple Degrees-of-Freedom(multi-DOF) and complex flow field structure.In this paper, a special kind of cable-driven parallel mechanism is firstly utilized as a new suspension method to conduct unsteady dynamic wind tunnel tests at high angles of attack, thereby providing experimental aerodynamic data. These tests include a wide range of multi-DOF coupled oscillatory motions with various amplitudes and frequencies. Then, for aerodynamic modeling and analysis, a novel data-driven Feature-Level Attention Recurrent neural network(FLAR) is proposed. This model incorporates a specially designed feature-level attention module that focuses on the state variables affecting the aerodynamic coefficients, thereby enhancing the physical interpretability of the aerodynamic model. Subsequently, spin maneuver simulations, using a mathematical model as the baseline, are conducted to validate the effectiveness of the FLAR. Finally, the results on wind tunnel data reveal that the FLAR accurately predicts aerodynamic coefficients, and observations through the visualization of attention scores identify the key state variables that affect the aerodynamic coefficients. It is concluded that the proposed FLAR enhances the interpretability of the aerodynamic model while achieving good prediction accuracy and generalization capability for multi-DOF coupling motion at high angles of attack.展开更多
Coral reef limestone(CRL)constitutes a distinctive marine carbonate formation with complex mechanical properties.This study investigates the multiscale damage and fracture mechanisms of CRL through integrated experime...Coral reef limestone(CRL)constitutes a distinctive marine carbonate formation with complex mechanical properties.This study investigates the multiscale damage and fracture mechanisms of CRL through integrated experimental testing,digital core technology,and theoretical modelling.Two CRL types with contrasting mesostructures were characterized across three scales.Macroscopically,CRL-I and CRL-II exhibited mean compressive strengths of 8.46 and 5.17 MPa,respectively.Mesoscopically,CRL-I featured small-scale highly interconnected pores,whilst CRL-II developed larger stratified pores with diminished connectivity.Microscopically,both CRL matrices demonstrated remarkable similarity in mineral composition and mechanical properties.A novel voxel average-based digital core scaling methodology was developed to facilitate numerical simulation of cross-scale damage processes,revealing network-progressive failure in CRL-I versus directional-brittle failure in CRL-II.Furthermore,a damage statistical constitutive model based on digital core technology and mesoscopic homogenisation theory established quantitative relationships between microelement strength distribution and macroscopic mechanical behavior.These findings illuminate the fundamental mechanisms through which mesoscopic structure governs the macroscopic mechanical properties of CRL.展开更多
To examine the effect of bedding angle upon burst proneness in terms of energy,phyllites with seven various bedding angles are selected for conventional uniaxial compression and single-cyclic loading eunloading uniaxi...To examine the effect of bedding angle upon burst proneness in terms of energy,phyllites with seven various bedding angles are selected for conventional uniaxial compression and single-cyclic loading eunloading uniaxial compression tests.The ejection and failure during compression process of phyllites are monitored in real-time by high-speed camera system.The results demonstrate that the phyllites with different bedding angles all consistently follow the linear energy storage and dissipation(LESD)law during compression.The ultimate energy storage of phyllites with varying bedding angles can be calculated precisely via using the LESD law.Based on this,four kinds of energy-based rockburst indices are applied to quantitatively assess the burst proneness for phyllites.Combined with the recorded images of high-speed camera system,ejection distance,and mass of rock fragments and powder,the burst proneness for phyllites with various bedding angles is qualitatively evaluated adopting the far-field ejection mass ratio.Next,burst proneness of anisotropic phyllites is assessed quantitatively and qualitatively.It is found that phyllites with bedding angles of 0°,15°,and 90°have a high burst proneness,and that with bedding angle of 30°has a medium burst proneness,whereas the ones with bedding angles of 45°,60°,and 75°have a low burst proneness.Finally,the published experimental data of shale and sandstone specimens with different bedding angles are extracted,and it is preliminarily verified that the bedding angle does not change the LESD law of rocks.展开更多
The fusion of infrared and visible images should emphasize the salient targets in the infrared image while preserving the textural details of the visible images.To meet these requirements,an autoencoder-based method f...The fusion of infrared and visible images should emphasize the salient targets in the infrared image while preserving the textural details of the visible images.To meet these requirements,an autoencoder-based method for infrared and visible image fusion is proposed.The encoder designed according to the optimization objective consists of a base encoder and a detail encoder,which is used to extract low-frequency and high-frequency information from the image.This extraction may lead to some information not being captured,so a compensation encoder is proposed to supplement the missing information.Multi-scale decomposition is also employed to extract image features more comprehensively.The decoder combines low-frequency,high-frequency and supplementary information to obtain multi-scale features.Subsequently,the attention strategy and fusion module are introduced to perform multi-scale fusion for image reconstruction.Experimental results on three datasets show that the fused images generated by this network effectively retain salient targets while being more consistent with human visual perception.展开更多
A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and...A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and development of the NMI model and then emphasize that the NMI model represents a new tool for identifying the basic physics of how climate change influences mid-to-high latitude weather extremes.The building of the NMI model took place over three main periods.In the 1990s,a nonlinear Schr?dinger(NLS)equation model was presented to describe atmospheric blocking as a wave packet;however,it could not depict the lifetime(10-20 days)of atmospheric blocking.In the 2000s,we proposed an NMI model of atmospheric blocking in a uniform basic flow by making a scale-separation assumption and deriving an eddyforced NLS equation.This model succeeded in describing the life cycle of atmospheric blocking.In the 2020s,the NMI model was extended to include the impact of a changing climate mainly by altering the basic zonal winds and the magnitude of the meridional background potential vorticity gradient(PVy).Model results show that when PVy is smaller,blocking has a weaker dispersion and a stronger nonlinearity,so blocking can be more persistent and have a larger zonal scale and weaker eastward movement,thus favoring stronger weather extremes.However,when PVy is much smaller and below a critical threshold under much stronger winter Arctic warming of global warming,atmospheric blocking becomes locally less persistent and shows a much stronger westward movement,which acts to inhibit local cold extremes.Such a case does not happen in summer under global warming because PVy fails to fall below the critical threshold.Thus,our theory indicates that global warming can render summer-blocking anticyclones and mid-to-high latitude heatwaves more persistent,intense,and widespread.展开更多
In this study,to better decide the effect of coal seam dip angle upon the dynamic change of the crossfusion in gas transport and storage areas during the progress of working face in the high gas thick coal seam,a two-...In this study,to better decide the effect of coal seam dip angle upon the dynamic change of the crossfusion in gas transport and storage areas during the progress of working face in the high gas thick coal seam,a two-dimensional physical simulation experiment regarded as the theoretical research was conducted to properly explore the variation law of overburden fracture.The results demonstrated that the boundary of the gas transport zone was located in the region of fracture separation.The boundary of the gas storage area was located in the abrupt penetration zone.Also,according to the information theory,the state of the gas transport and storage areas was determined by the changing trend of the fracture rate and fracture entropy.The mathematical representation model of the dip effect in gas transport and storage areas was established.The criteria upon which the regional location of the gas transport area and gas storage area can be based were put forward.The cross-fusion evolution process of the dip effect in gas transport and storage areas was revealed as well.The research results could provide guidance for realising directional and accurate gas extraction.展开更多
AIM:To investigate how angles kappa and alpha affect postoperative visual quality in patients with multifocal intraocular lens(mIOLs)implantation.METHODS:Retrospective cases series.A total of 46 patients(46 eyes)who u...AIM:To investigate how angles kappa and alpha affect postoperative visual quality in patients with multifocal intraocular lens(mIOLs)implantation.METHODS:Retrospective cases series.A total of 46 patients(46 eyes)who underwent phacoemulsification were subsumed.The correlation between Preoperative angles kappa and alpha,wave-front aberrations and objective visual quality of cornea,internal,and total eye after surgery were analyzed using iTrace.RESULTS:The magnitude of angle kappa was negatively correlated with internal and total modulation transfer function(MTF)at 3 mm;the magnitude of angle kappa was positively correlated with astigmatism,trefoil,higher-order aberrations(HOAs)of both internal and total eye at 3 mm.The magnitude of angle alpha was negatively correlated with total MTF and total Strehl ratio at 3 mm.The magnitude of angle alpha was positively correlated with corneal coma at 5 mm,internal astigmatism at both 3 mm and 5 mm,and total spherical aberration(SA)at 3 mm.Multivariate linear regression analysis showed that,among candidate independent variables(kappa,alpha,astigmatism,SA,coma,trefoil,and HOAs),astigmatism is the only independent factor for altering corneal MTF at 3 mm and 5 mm;astigmatism and HOAs emerged as independent factors for altering internal MTF at 3 mm and 5 mm,and total MTF at 3 mm;astigmatism,SA and HOAs emerged as independent factors for altering total MTF at 5 mm.CONCLUSION:With greater preoperative angle kappa or angle alpha,patients who accept mIOL implantation tend to have larger internal astigmatism and HOAs,which resulting in poor visual quality,especially those with small pupil size.展开更多
AIM:To explore the effect of Alpha angle and Kappa angle before multifocal intraocular lenses(MIOLs)implantation on postoperative visual quality of patients.METHODS:Before and 3mo after cataract surgery,Alpha angle an...AIM:To explore the effect of Alpha angle and Kappa angle before multifocal intraocular lenses(MIOLs)implantation on postoperative visual quality of patients.METHODS:Before and 3mo after cataract surgery,Alpha angle and Kappa angle were collected using IOL Master 700,iTrace,and Pentacam for clinical observation.Postoperative visual quality indicators,including high-order aberrations(HOA),modulation transfer function(MTF)and point spread function(PSF),were collected using iTrace.multiple linear regression analysis was used to analyze the correlation of the Kappa angle and the Alpha angle with age,axial length(AL),anterior chamber depth(ACD),keratometry(K),lens thickness(LT)and corneal white to white distance(WTW).Pearson correlation coefficient was used to analyze the correlation between Alpha angle and Kappa angle;Bland Altman analysis was used to evaluate the consistency of pairwise detection results of three instruments.RESULTS:The Alpha angle was modeled as Alpha=2.230+0.003×age-0.036×AL-0.025×K-0.058×WTW and the Kappa angle was modeled as Kappa=0.685+0.003×age-0.013×K-0.061×WTW.The correlation between the total Alpha angle and Kappa angle of the three instruments was weakly positive(r=0.291,P=0.000).Comparing the measurement of Alpha angle and Kappa angle using three instruments,only IOL Master 700 and iTrace showed good consistency in measuring Kappa angle(P=0.4254).After 3mo of surgery,the Alpha angle and Kappa angle significantly decreased(P=0.011,0.018;P=0.008,0.036).△Kappa=1.136-0.021×AL-0.013×K.Kappa angle could positively predict HOA(β=0.18,P=0.000),MTF(β=0.171,P=0.000),PSF(β=0.088,P=0.000),Alpha angle cannot(P>0.05).CONCLUSION:The patients with older age,flatter K and shorter WTW should be alert to the possibility of larger Alpha angle and Kappa angle.Alpha angle should also consider the factor of AL.When selecting patients with MIOLs implantation,there is no need to consider the Alpha angle.Careful consideration should be given to the Kappa angle,and the preoperative standard of<0.5 mm can refer to△Kappa=1.136-0.021×AL-0.013×K and be appropriately relaxed.展开更多
Mental health problems and potential psychological crises affect the healthy growth and learning performance of college students.Effective and suitable prevention of psychological crises among college students is a co...Mental health problems and potential psychological crises affect the healthy growth and learning performance of college students.Effective and suitable prevention of psychological crises among college students is a continuous challenge university managers face.To explore a method of preventing psychological crises among college students,we measured 38661 students by using SCL-90(symptom check list-90)and screened out 5790 students with positive results.Then,we measured 33188 students by using PHQ-9(patient health questionnaire-9)and screened out 603 students with suicidal ideation or behavior;we interviewed 392 students by using GAQ(growth adversity questionnaire).The number of students who had positive results at both phases is 155.As a result,we obtained a data set(N=76)by integrating the students who tested positive on the PHQ-9(i.e.total score≥20)with those who completed the PHQ-9 and GAQ.In addition,we obtained a data set(N=50)by excluding the cases in which the GAQ score is 0.With regard to QCA(qualitative comparative analysis)results,the data set(N=76)exhibits 5 constellations of solutions with a coverage rate greater than 0.7,and the first eight indicators of the PHQ-9 constitute the explanatory variables in the combined solutions.About the data set(N=50),the combined solutions are extremely complicated and the explanatory variables encompass indicators from both the PHQ-9 and GAQ.All these mean that the multi-scale could more comprehensively reflect mental health states of college students,thus enhance the accuracy and effectiveness of the corresponding hierarchical intervention,and finally provide support for preventing psychological crises in universities.展开更多
Water electrolyzers play a crucial role in green hydrogen production.However,their efficiency and scalability are often compromised by bubble dynamics across various scales,from nanoscale to macroscale components.This...Water electrolyzers play a crucial role in green hydrogen production.However,their efficiency and scalability are often compromised by bubble dynamics across various scales,from nanoscale to macroscale components.This review explores multi-scale modeling as a tool to visualize multi-phase flow and improve mass transport in water electrolyzers.At the nanoscale,molecular dynamics(MD)simulations reveal how electrode surface features and wettability influence nanobubble nucleation and stability.Moving to the mesoscale,models such as volume of fluid(VOF)and lattice Boltzmann method(LBM)shed light on bubble transport in porous transport layers(PTLs).These insights inform innovative designs,including gradient porosity and hydrophilic-hydrophobic patterning,aimed at minimizing gas saturation.At the macroscale,VOF simulations elucidate two-phase flow regimes within channels,showing how flow field geometry and wettability affect bubble discharging.Moreover,artificial intelligence(AI)-driven surrogate models expedite the optimization process,allowing for rapid exploration of structural parameters in channel-rib flow fields and porous flow field designs.By integrating these approaches,we can bridge theoretical insights with experimental validation,ultimately enhancing water electrolyzer performance,reducing costs,and advancing affordable,high-efficiency hydrogen production.展开更多
Dear Editor,X-linked retinoschisis(XLRS)is a rare X-linked recessive disorder predominantly afflicting young males.The schisis of the retinal layers is a result of deleterious mutations in the RS1 gene.Insufficient ep...Dear Editor,X-linked retinoschisis(XLRS)is a rare X-linked recessive disorder predominantly afflicting young males.The schisis of the retinal layers is a result of deleterious mutations in the RS1 gene.Insufficient epidemiological data has caused significant variation in reported global prevalence,with estimates fluctuating between 1 in 5000 and 1 in 30000 individuals[1].A large follow-up multicenter study recently published has yielded noteworthy findings concerning the phenotypic spectrum,long-term natural history,and genotype of XLRS.The investigation revealed a significant variability in visual function and disease progression,with particular variants of the RS1 gene displaying diverse phenotypic expressions,suggesting the intricate genetic basis underlying this disorder[2].The range of visual impairments associated with XLRS is extensive,varying from minor to severe.This condition is also characterized by specific retinal abnormalities,including radial streaks emanating from a divided central fovea,schisis affecting the inner layers of the retina in peripheral areas,and a diminished amplitude ratio of b-to a-wave,or even an electronegative electroretinography(ERG)[3].At their initial consultation,the majority of individuals with XLRS exhibit visual acuity(VA)levels between 20/60 and 20/120.However,there is a significant diversity in the condition’s presentation and progression,even among relatives,with VA levels spanning from near-normal to complete loss of sight[4-5].While vision tends to be reasonably consistent over several years for those with XLRS,there is documentation of a more rapid decline in later adulthood,specifically during the fourth and fifth decades,due to central retinal degeneration[5-7].Moreover,those with XLRS face an elevated risk for serious visual issues,such as retinal detachment,vitreous hemorrhages,and neovascular glaucoma[4].Female carriers could be found with slightly abnormal retinal changes without clinical symptoms[5].Even within the same family,the manifestation and progression of the condition can vary greatly,with individuals experiencing anything from nearly normal vision to complete loss of sight[8-9].Earlier investigations have revealed that retinoschisisrelated cystoid degeneration can impact multiple layers of the retina,beginning at the retinal nerve fiber zone and continuing to the nuclear stratum,with considerable fluctuation in the severity of the schisis[10-13].展开更多
文摘Installing internal bulkheads in a composite bucket foundation alters the rotational symmetry characteristic of a single-compartment bucket foundation,consequently influencing the stress distribution within the bucket and surrounding soil.During the seabed penetration of a spudcan from a jack-up wind turbine installation vessel,an angle may form between the spudcan’s axis and the axis of symmetry of the adjacent composite bucket foundation in the horizontal plane.Such a misalignment may affect load distribution and the non-uniform interaction between the foundation,soil,and spudcan,ultimately influencing the foundation’s stability.This study employs physical model tests to ascertain the trends in end resistance during spudcan penetration in sand,the extent of soil disturbance,and the backflow condition.The finite element coupled Eulerian-Lagrangian method is validated and utilized to determine the range of penetration angles that induce alterations in the maximum vertical displacement and tilt rate of the composite bucket foundation in sand.The differential contact stress distribution at the base of the bucket is analyzed,with qualitative criteria for sand backflow provided.Findings demonstrate that the maximum vertical displacement and tilt rate of the composite bucket foundation display a“wave-like”variation with the increasing spudcan penetration angle,peaking when the angle between the spudcan and bulkhead is the smallest.Stress distribution is predominantly concentrated at the base and apex of the bucket,becoming increasingly uneven as the penetration angle deviates from the foundation’s symmetry axis.The maximum stress gradually shifts to the junction of the bulkhead and bucket bottom on the side with the shortest net distance from the spudcan.Considering the in-place stability and stress state of the composite bucket foundation is therefore imperative,and particular attention should be paid to the foundation’s state when the angle between the spudcan and bulkhead is small.
基金Opening Foundation of Key Laboratory of Explosive Energy Utilization and Control,Anhui Province(BP20240104)Graduate Innovation Program of China University of Mining and Technology(2024WLJCRCZL049)Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX24_2701)。
文摘Because of the challenge of compounding lightweight,high-strength Ti/Al alloys due to their considerable disparity in properties,Al 6063 as intermediate layer was proposed to fabricate TC4/Al 6063/Al 7075 three-layer composite plate by explosive welding.The microscopic properties of each bonding interface were elucidated through field emission scanning electron microscope and electron backscattered diffraction(EBSD).A methodology combining finite element method-smoothed particle hydrodynamics(FEM-SPH)and molecular dynamics(MD)was proposed for the analysis of the forming and evolution characteristics of explosive welding interfaces at multi-scale.The results demonstrate that the bonding interface morphologies of TC4/Al 6063 and Al 6063/Al 7075 exhibit a flat and wavy configuration,without discernible defects or cracks.The phenomenon of grain refinement is observed in the vicinity of the two bonding interfaces.Furthermore,the degree of plastic deformation of TC4 and Al 7075 is more pronounced than that of Al 6063 in the intermediate layer.The interface morphology characteristics obtained by FEM-SPH simulation exhibit a high degree of similarity to the experimental results.MD simulations reveal that the diffusion of interfacial elements predominantly occurs during the unloading phase,and the simulated thickness of interfacial diffusion aligns well with experimental outcomes.The introduction of intermediate layer in the explosive welding process can effectively produce high-quality titanium/aluminum alloy composite plates.Furthermore,this approach offers a multi-scale simulation strategy for the study of explosive welding bonding interfaces.
基金funded by the Joint Fund for Regional Innovation and Development of National Natural Science Foundation of China(U21A20143)the National Science Fund for Excellent Young Scholars(52322607)the Excellent Youth Foundation of Heilongjiang Scientific Committee(YQ2022E028)。
文摘Improving the volumetric energy density of supercapacitors is essential for practical applications,which highly relies on the dense storage of ions in carbon-based electrodes.The functional units of carbon-based electrode exhibit multi-scale structural characteristics including macroscopic electrode morphologies,mesoscopic microcrystals and pores,and microscopic defects and dopants in the carbon basal plane.Therefore,the ordered combination of multi-scale structures of carbon electrode is crucial for achieving dense energy storage and high volumetric performance by leveraging the functions of various scale structu re.Considering that previous reviews have focused more on the discussion of specific scale structu re of carbon electrodes,this review takes a multi-scale perspective in which recent progresses regarding the structureperformance relationship,underlying mechanism and directional design of carbon-based multi-scale structures including carbon morphology,pore structure,carbon basal plane micro-environment and electrode technology on dense energy storage and volumetric property of supercapacitors are systematically discussed.We analyzed in detail the effects of the morphology,pore,and micro-environment of carbon electrode materials on ion dense storage,summarized the specific effects of different scale structures on volumetric property and recent research progress,and proposed the mutual influence and trade-off relationship between various scale structures.In addition,the challenges and outlooks for improving the dense storage and volumetric performance of carbon-based supercapacitors are analyzed,which can provide feasible technical reference and guidance for the design and manufacture of dense carbon-based electrode materials.
基金supported by the Natural Science Foundation of the Anhui Higher Education Institutions of China(Grant Nos.2023AH040149 and 2024AH051915)the Anhui Provincial Natural Science Foundation(Grant No.2208085MF168)+1 种基金the Science and Technology Innovation Tackle Plan Project of Maanshan(Grant No.2024RGZN001)the Scientific Research Fund Project of Anhui Medical University(Grant No.2023xkj122).
文摘Convolutional neural networks(CNNs)-based medical image segmentation technologies have been widely used in medical image segmentation because of their strong representation and generalization abilities.However,due to the inability to effectively capture global information from images,CNNs can easily lead to loss of contours and textures in segmentation results.Notice that the transformer model can effectively capture the properties of long-range dependencies in the image,and furthermore,combining the CNN and the transformer can effectively extract local details and global contextual features of the image.Motivated by this,we propose a multi-branch and multi-scale attention network(M2ANet)for medical image segmentation,whose architecture consists of three components.Specifically,in the first component,we construct an adaptive multi-branch patch module for parallel extraction of image features to reduce information loss caused by downsampling.In the second component,we apply residual block to the well-known convolutional block attention module to enhance the network’s ability to recognize important features of images and alleviate the phenomenon of gradient vanishing.In the third component,we design a multi-scale feature fusion module,in which we adopt adaptive average pooling and position encoding to enhance contextual features,and then multi-head attention is introduced to further enrich feature representation.Finally,we validate the effectiveness and feasibility of the proposed M2ANet method through comparative experiments on four benchmark medical image segmentation datasets,particularly in the context of preserving contours and textures.
基金supported by the Natural Science Foundation of China(Grant No.42302170)National Postdoctoral Innovative Talent Support Program(Grant No.BX20220062)+3 种基金CNPC Innovation Found(Grant No.2022DQ02-0104)National Science Foundation of Heilongjiang Province of China(Grant No.YQ2023D001)Postdoctoral Science Foundation of Heilongjiang Province of China(Grant No.LBH-Z22091)the Natural Science Foundation of Shandong Province(Grant No.ZR2022YQ30).
文摘Prediction of production decline and evaluation of the adsorbed/free gas ratio are critical for determining the lifespan and production status of shale gas wells.Traditional production prediction methods have some shortcomings because of the low permeability and tightness of shale,complex gas flow behavior of multi-scale gas transport regions and multiple gas transport mechanism superpositions,and complex and variable production regimes of shale gas wells.Recent research has demonstrated the existence of a multi-stage isotope fractionation phenomenon during shale gas production,with the fractionation characteristics of each stage associated with the pore structure,gas in place(GIP),adsorption/desorption,and gas production process.This study presents a new approach for estimating shale gas well production and evaluating the adsorbed/free gas ratio throughout production using isotope fractionation techniques.A reservoir-scale carbon isotope fractionation(CIF)model applicable to the production process of shale gas wells was developed for the first time in this research.In contrast to the traditional model,this model improves production prediction accuracy by simultaneously fitting the gas production rate and δ^(13)C_(1) data and provides a new evaluation method of the adsorbed/free gas ratio during shale gas production.The results indicate that the diffusion and adsorption/desorption properties of rock,bottom-hole flowing pressure(BHP)of gas well,and multi-scale gas transport regions of the reservoir all affect isotope fractionation,with the diffusion and adsorption/desorption parameters of rock having the greatest effect on isotope fractionation being D∗/D,PL,VL,α,and others in that order.We effectively tested the universality of the four-stage isotope fractionation feature and revealed a unique isotope fractionation mechanism caused by the superimposed coupling of multi-scale gas transport regions during shale gas well production.Finally,we applied the established CIF model to a shale gas well in the Sichuan Basin,China,and calculated the estimated ultimate recovery(EUR)of the well to be 3.33×10^(8) m^(3);the adsorbed gas ratio during shale gas production was 1.65%,10.03%,and 23.44%in the first,fifth,and tenth years,respectively.The findings are significant for understanding the isotope fractionation mechanism during natural gas transport in complex systems and for formulating and optimizing unconventional natural gas development strategies.
基金Supported by Iranian University of Medical Sciences(code:IR.IUMS.REC.1401.371).
文摘AIM:To identify topographic determinants of the anterior chamber angle(ACA)in patients with keratoconus(KCN).METHODS:Four hundred and ten eyes of 294 patients with KCN were recruited for this study.First,complete ocular examinations were performed for all patients,including visual acuity measurement,refraction,and slit-lamp biomicroscopy.Then,all participants underwent corneal imaging by the Oculus Pentacam HR.RESULTS:The mean age of the participants was 32.40±8.52y(15-60y)and 69.5%of them were male.The mean ACA was 38.47°±5.75°(range:14.40°to 56.50°)in the whole sample,38.24°±6.00°in males,and 38.98°±5.11°in females(P=0.447).The mean ACA was significantly different among different groups of cone morphology,as patients with nipple cones showed the lowest mean ACA.Moreover,there were statistically significant differences in the mean ACA among different groups of cone locations,with patients having central cones exhibiting the lowest mean ACA(P<0.001).Anterior and posterior Q values were significantly,directly correlated with ACA(anterior Q:r=0.122,P=0.014,posterior Q:r=0.192,P<0.001).CONCLUSION:This study provides critical insights into the risk factors for ACA narrowing in KCN patients,which is essential for planning intraocular surgeries.Patients with nipple and central cones exhibited the most significant ACA narrowing.Additionally,more negative Q-values are associated with increased ACA narrowing,highlighting the need for targeted diagnostic and therapeutic strategies.
文摘To improve the vertical axis wind turbine(VAWT)design,the angle of attack(AOA)and airfoil data must be treated correctly.The present paper develops a method for determining AOA on a VAWT based on computational fluid dynamics(CFD)analysis.First,a CFD analysis of a two-bladed VAWT equipped with a NACA 0012 airfoil is conducted.The thrust and power coefficients are validated through experiments.Second,the blade force and velocity data at monitoring points are collected.The AOA at different azimuth angles is determined by removing the blade self-induction at the monitoring point.Then,the lift and drag coefficients as a function of AOA are extracted.Results show that this method is independent of the monitoring points selection located at certain distance to the blades and the extracted dynamic stall hysteresis is more precise than the one with the“usual”method without considering the self-induction from bound vortices.
基金supported by the National Natural Science Foundation of China(62272049,62236006,62172045)the Key Projects of Beijing Union University(ZKZD202301).
文摘In recent years,gait-based emotion recognition has been widely applied in the field of computer vision.However,existing gait emotion recognition methods typically rely on complete human skeleton data,and their accuracy significantly declines when the data is occluded.To enhance the accuracy of gait emotion recognition under occlusion,this paper proposes a Multi-scale Suppression Graph ConvolutionalNetwork(MS-GCN).TheMS-GCN consists of three main components:Joint Interpolation Module(JI Moudle),Multi-scale Temporal Convolution Network(MS-TCN),and Suppression Graph Convolutional Network(SGCN).The JI Module completes the spatially occluded skeletal joints using the(K-Nearest Neighbors)KNN interpolation method.The MS-TCN employs convolutional kernels of various sizes to comprehensively capture the emotional information embedded in the gait,compensating for the temporal occlusion of gait information.The SGCN extracts more non-prominent human gait features by suppressing the extraction of key body part features,thereby reducing the negative impact of occlusion on emotion recognition results.The proposed method is evaluated on two comprehensive datasets:Emotion-Gait,containing 4227 real gaits from sources like BML,ICT-Pollick,and ELMD,and 1000 synthetic gaits generated using STEP-Gen technology,and ELMB,consisting of 3924 gaits,with 1835 labeled with emotions such as“Happy,”“Sad,”“Angry,”and“Neutral.”On the standard datasets Emotion-Gait and ELMB,the proposed method achieved accuracies of 0.900 and 0.896,respectively,attaining performance comparable to other state-ofthe-artmethods.Furthermore,on occlusion datasets,the proposedmethod significantly mitigates the performance degradation caused by occlusion compared to other methods,the accuracy is significantly higher than that of other methods.
基金supported by the National Natural Science Foundation of China(Nos.12172315,12072304,11702232)the Fujian Provincial Natural Science Foundation,China(No.2021J01050)the Aeronautical Science Foundation of China(No.20220013068002).
文摘Unsteady aerodynamic characteristics at high angles of attack are of great importance to the design and development of advanced fighter aircraft, which are characterized by post-stall maneuverability with multiple Degrees-of-Freedom(multi-DOF) and complex flow field structure.In this paper, a special kind of cable-driven parallel mechanism is firstly utilized as a new suspension method to conduct unsteady dynamic wind tunnel tests at high angles of attack, thereby providing experimental aerodynamic data. These tests include a wide range of multi-DOF coupled oscillatory motions with various amplitudes and frequencies. Then, for aerodynamic modeling and analysis, a novel data-driven Feature-Level Attention Recurrent neural network(FLAR) is proposed. This model incorporates a specially designed feature-level attention module that focuses on the state variables affecting the aerodynamic coefficients, thereby enhancing the physical interpretability of the aerodynamic model. Subsequently, spin maneuver simulations, using a mathematical model as the baseline, are conducted to validate the effectiveness of the FLAR. Finally, the results on wind tunnel data reveal that the FLAR accurately predicts aerodynamic coefficients, and observations through the visualization of attention scores identify the key state variables that affect the aerodynamic coefficients. It is concluded that the proposed FLAR enhances the interpretability of the aerodynamic model while achieving good prediction accuracy and generalization capability for multi-DOF coupling motion at high angles of attack.
基金National Key Research and Development Program of China (No.2021YFC3100800)the National Natural Science Foundation of China (Nos.42407235 and 42271026)+1 种基金the Project of Sanya Yazhou Bay Science and Technology City (No.SCKJ-JYRC-2023-54)supported by the Hefei advanced computing center
文摘Coral reef limestone(CRL)constitutes a distinctive marine carbonate formation with complex mechanical properties.This study investigates the multiscale damage and fracture mechanisms of CRL through integrated experimental testing,digital core technology,and theoretical modelling.Two CRL types with contrasting mesostructures were characterized across three scales.Macroscopically,CRL-I and CRL-II exhibited mean compressive strengths of 8.46 and 5.17 MPa,respectively.Mesoscopically,CRL-I featured small-scale highly interconnected pores,whilst CRL-II developed larger stratified pores with diminished connectivity.Microscopically,both CRL matrices demonstrated remarkable similarity in mineral composition and mechanical properties.A novel voxel average-based digital core scaling methodology was developed to facilitate numerical simulation of cross-scale damage processes,revealing network-progressive failure in CRL-I versus directional-brittle failure in CRL-II.Furthermore,a damage statistical constitutive model based on digital core technology and mesoscopic homogenisation theory established quantitative relationships between microelement strength distribution and macroscopic mechanical behavior.These findings illuminate the fundamental mechanisms through which mesoscopic structure governs the macroscopic mechanical properties of CRL.
基金supported by the National Natural Science Foundation of China(Grant No.42077244).
文摘To examine the effect of bedding angle upon burst proneness in terms of energy,phyllites with seven various bedding angles are selected for conventional uniaxial compression and single-cyclic loading eunloading uniaxial compression tests.The ejection and failure during compression process of phyllites are monitored in real-time by high-speed camera system.The results demonstrate that the phyllites with different bedding angles all consistently follow the linear energy storage and dissipation(LESD)law during compression.The ultimate energy storage of phyllites with varying bedding angles can be calculated precisely via using the LESD law.Based on this,four kinds of energy-based rockburst indices are applied to quantitatively assess the burst proneness for phyllites.Combined with the recorded images of high-speed camera system,ejection distance,and mass of rock fragments and powder,the burst proneness for phyllites with various bedding angles is qualitatively evaluated adopting the far-field ejection mass ratio.Next,burst proneness of anisotropic phyllites is assessed quantitatively and qualitatively.It is found that phyllites with bedding angles of 0°,15°,and 90°have a high burst proneness,and that with bedding angle of 30°has a medium burst proneness,whereas the ones with bedding angles of 45°,60°,and 75°have a low burst proneness.Finally,the published experimental data of shale and sandstone specimens with different bedding angles are extracted,and it is preliminarily verified that the bedding angle does not change the LESD law of rocks.
基金Supported by the Henan Province Key Research and Development Project(231111211300)the Central Government of Henan Province Guides Local Science and Technology Development Funds(Z20231811005)+2 种基金Henan Province Key Research and Development Project(231111110100)Henan Provincial Outstanding Foreign Scientist Studio(GZS2024006)Henan Provincial Joint Fund for Scientific and Technological Research and Development Plan(Application and Overcoming Technical Barriers)(242103810028)。
文摘The fusion of infrared and visible images should emphasize the salient targets in the infrared image while preserving the textural details of the visible images.To meet these requirements,an autoencoder-based method for infrared and visible image fusion is proposed.The encoder designed according to the optimization objective consists of a base encoder and a detail encoder,which is used to extract low-frequency and high-frequency information from the image.This extraction may lead to some information not being captured,so a compensation encoder is proposed to supplement the missing information.Multi-scale decomposition is also employed to extract image features more comprehensively.The decoder combines low-frequency,high-frequency and supplementary information to obtain multi-scale features.Subsequently,the attention strategy and fusion module are introduced to perform multi-scale fusion for image reconstruction.Experimental results on three datasets show that the fused images generated by this network effectively retain salient targets while being more consistent with human visual perception.
基金supported by the National Natural Science Foundation of China(Grant Nos.42150204 and 2288101)supported by the China National Postdoctoral Program for Innovative Talents(BX20230045)the China Postdoctoral Science Foundation(2023M730279)。
文摘A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and development of the NMI model and then emphasize that the NMI model represents a new tool for identifying the basic physics of how climate change influences mid-to-high latitude weather extremes.The building of the NMI model took place over three main periods.In the 1990s,a nonlinear Schr?dinger(NLS)equation model was presented to describe atmospheric blocking as a wave packet;however,it could not depict the lifetime(10-20 days)of atmospheric blocking.In the 2000s,we proposed an NMI model of atmospheric blocking in a uniform basic flow by making a scale-separation assumption and deriving an eddyforced NLS equation.This model succeeded in describing the life cycle of atmospheric blocking.In the 2020s,the NMI model was extended to include the impact of a changing climate mainly by altering the basic zonal winds and the magnitude of the meridional background potential vorticity gradient(PVy).Model results show that when PVy is smaller,blocking has a weaker dispersion and a stronger nonlinearity,so blocking can be more persistent and have a larger zonal scale and weaker eastward movement,thus favoring stronger weather extremes.However,when PVy is much smaller and below a critical threshold under much stronger winter Arctic warming of global warming,atmospheric blocking becomes locally less persistent and shows a much stronger westward movement,which acts to inhibit local cold extremes.Such a case does not happen in summer under global warming because PVy fails to fall below the critical threshold.Thus,our theory indicates that global warming can render summer-blocking anticyclones and mid-to-high latitude heatwaves more persistent,intense,and widespread.
基金supported by the National Natural Science Foundation of China(No.5217-4205)Shaanxi Provincial Outstanding Youth Science Fund Project(No.2023-JC-JQ-40)+4 种基金National Key Research and Development Project(No.2023YFC3009004)Key Project of Shaanxi Provincial Department of Education(No.22JY040)Xinjiang Uygur Autonomous Region Key Research and Development Task Special Project(No.2022B01034-3)Key Laboratory of Green Coal Mining in Xinjiang,Ministry of Education(No.KLXGY-KA2404)Shaanxi Provincial Key Research and Development Task General Project(No.2024GX–YBXM-490)。
文摘In this study,to better decide the effect of coal seam dip angle upon the dynamic change of the crossfusion in gas transport and storage areas during the progress of working face in the high gas thick coal seam,a two-dimensional physical simulation experiment regarded as the theoretical research was conducted to properly explore the variation law of overburden fracture.The results demonstrated that the boundary of the gas transport zone was located in the region of fracture separation.The boundary of the gas storage area was located in the abrupt penetration zone.Also,according to the information theory,the state of the gas transport and storage areas was determined by the changing trend of the fracture rate and fracture entropy.The mathematical representation model of the dip effect in gas transport and storage areas was established.The criteria upon which the regional location of the gas transport area and gas storage area can be based were put forward.The cross-fusion evolution process of the dip effect in gas transport and storage areas was revealed as well.The research results could provide guidance for realising directional and accurate gas extraction.
文摘AIM:To investigate how angles kappa and alpha affect postoperative visual quality in patients with multifocal intraocular lens(mIOLs)implantation.METHODS:Retrospective cases series.A total of 46 patients(46 eyes)who underwent phacoemulsification were subsumed.The correlation between Preoperative angles kappa and alpha,wave-front aberrations and objective visual quality of cornea,internal,and total eye after surgery were analyzed using iTrace.RESULTS:The magnitude of angle kappa was negatively correlated with internal and total modulation transfer function(MTF)at 3 mm;the magnitude of angle kappa was positively correlated with astigmatism,trefoil,higher-order aberrations(HOAs)of both internal and total eye at 3 mm.The magnitude of angle alpha was negatively correlated with total MTF and total Strehl ratio at 3 mm.The magnitude of angle alpha was positively correlated with corneal coma at 5 mm,internal astigmatism at both 3 mm and 5 mm,and total spherical aberration(SA)at 3 mm.Multivariate linear regression analysis showed that,among candidate independent variables(kappa,alpha,astigmatism,SA,coma,trefoil,and HOAs),astigmatism is the only independent factor for altering corneal MTF at 3 mm and 5 mm;astigmatism and HOAs emerged as independent factors for altering internal MTF at 3 mm and 5 mm,and total MTF at 3 mm;astigmatism,SA and HOAs emerged as independent factors for altering total MTF at 5 mm.CONCLUSION:With greater preoperative angle kappa or angle alpha,patients who accept mIOL implantation tend to have larger internal astigmatism and HOAs,which resulting in poor visual quality,especially those with small pupil size.
基金Supported by National Natural Science Foundation of China(No.81902751).
文摘AIM:To explore the effect of Alpha angle and Kappa angle before multifocal intraocular lenses(MIOLs)implantation on postoperative visual quality of patients.METHODS:Before and 3mo after cataract surgery,Alpha angle and Kappa angle were collected using IOL Master 700,iTrace,and Pentacam for clinical observation.Postoperative visual quality indicators,including high-order aberrations(HOA),modulation transfer function(MTF)and point spread function(PSF),were collected using iTrace.multiple linear regression analysis was used to analyze the correlation of the Kappa angle and the Alpha angle with age,axial length(AL),anterior chamber depth(ACD),keratometry(K),lens thickness(LT)and corneal white to white distance(WTW).Pearson correlation coefficient was used to analyze the correlation between Alpha angle and Kappa angle;Bland Altman analysis was used to evaluate the consistency of pairwise detection results of three instruments.RESULTS:The Alpha angle was modeled as Alpha=2.230+0.003×age-0.036×AL-0.025×K-0.058×WTW and the Kappa angle was modeled as Kappa=0.685+0.003×age-0.013×K-0.061×WTW.The correlation between the total Alpha angle and Kappa angle of the three instruments was weakly positive(r=0.291,P=0.000).Comparing the measurement of Alpha angle and Kappa angle using three instruments,only IOL Master 700 and iTrace showed good consistency in measuring Kappa angle(P=0.4254).After 3mo of surgery,the Alpha angle and Kappa angle significantly decreased(P=0.011,0.018;P=0.008,0.036).△Kappa=1.136-0.021×AL-0.013×K.Kappa angle could positively predict HOA(β=0.18,P=0.000),MTF(β=0.171,P=0.000),PSF(β=0.088,P=0.000),Alpha angle cannot(P>0.05).CONCLUSION:The patients with older age,flatter K and shorter WTW should be alert to the possibility of larger Alpha angle and Kappa angle.Alpha angle should also consider the factor of AL.When selecting patients with MIOLs implantation,there is no need to consider the Alpha angle.Careful consideration should be given to the Kappa angle,and the preoperative standard of<0.5 mm can refer to△Kappa=1.136-0.021×AL-0.013×K and be appropriately relaxed.
文摘Mental health problems and potential psychological crises affect the healthy growth and learning performance of college students.Effective and suitable prevention of psychological crises among college students is a continuous challenge university managers face.To explore a method of preventing psychological crises among college students,we measured 38661 students by using SCL-90(symptom check list-90)and screened out 5790 students with positive results.Then,we measured 33188 students by using PHQ-9(patient health questionnaire-9)and screened out 603 students with suicidal ideation or behavior;we interviewed 392 students by using GAQ(growth adversity questionnaire).The number of students who had positive results at both phases is 155.As a result,we obtained a data set(N=76)by integrating the students who tested positive on the PHQ-9(i.e.total score≥20)with those who completed the PHQ-9 and GAQ.In addition,we obtained a data set(N=50)by excluding the cases in which the GAQ score is 0.With regard to QCA(qualitative comparative analysis)results,the data set(N=76)exhibits 5 constellations of solutions with a coverage rate greater than 0.7,and the first eight indicators of the PHQ-9 constitute the explanatory variables in the combined solutions.About the data set(N=50),the combined solutions are extremely complicated and the explanatory variables encompass indicators from both the PHQ-9 and GAQ.All these mean that the multi-scale could more comprehensively reflect mental health states of college students,thus enhance the accuracy and effectiveness of the corresponding hierarchical intervention,and finally provide support for preventing psychological crises in universities.
基金supported by a grant from the Research Grants Council of the Hong Kong Special Administrative Region,China(Project No.15308024)a grant from Research Centre for Carbon-Strategic Catalysis,The Hong Kong Polytechnic University(CE2X).
文摘Water electrolyzers play a crucial role in green hydrogen production.However,their efficiency and scalability are often compromised by bubble dynamics across various scales,from nanoscale to macroscale components.This review explores multi-scale modeling as a tool to visualize multi-phase flow and improve mass transport in water electrolyzers.At the nanoscale,molecular dynamics(MD)simulations reveal how electrode surface features and wettability influence nanobubble nucleation and stability.Moving to the mesoscale,models such as volume of fluid(VOF)and lattice Boltzmann method(LBM)shed light on bubble transport in porous transport layers(PTLs).These insights inform innovative designs,including gradient porosity and hydrophilic-hydrophobic patterning,aimed at minimizing gas saturation.At the macroscale,VOF simulations elucidate two-phase flow regimes within channels,showing how flow field geometry and wettability affect bubble discharging.Moreover,artificial intelligence(AI)-driven surrogate models expedite the optimization process,allowing for rapid exploration of structural parameters in channel-rib flow fields and porous flow field designs.By integrating these approaches,we can bridge theoretical insights with experimental validation,ultimately enhancing water electrolyzer performance,reducing costs,and advancing affordable,high-efficiency hydrogen production.
基金Supported by Capital’s Funds for Health Improvement and Research(No.2024-2-4087)Central Guidance for Local Scientific and Technological Development Funding Projects(No.2022ZY0026).
文摘Dear Editor,X-linked retinoschisis(XLRS)is a rare X-linked recessive disorder predominantly afflicting young males.The schisis of the retinal layers is a result of deleterious mutations in the RS1 gene.Insufficient epidemiological data has caused significant variation in reported global prevalence,with estimates fluctuating between 1 in 5000 and 1 in 30000 individuals[1].A large follow-up multicenter study recently published has yielded noteworthy findings concerning the phenotypic spectrum,long-term natural history,and genotype of XLRS.The investigation revealed a significant variability in visual function and disease progression,with particular variants of the RS1 gene displaying diverse phenotypic expressions,suggesting the intricate genetic basis underlying this disorder[2].The range of visual impairments associated with XLRS is extensive,varying from minor to severe.This condition is also characterized by specific retinal abnormalities,including radial streaks emanating from a divided central fovea,schisis affecting the inner layers of the retina in peripheral areas,and a diminished amplitude ratio of b-to a-wave,or even an electronegative electroretinography(ERG)[3].At their initial consultation,the majority of individuals with XLRS exhibit visual acuity(VA)levels between 20/60 and 20/120.However,there is a significant diversity in the condition’s presentation and progression,even among relatives,with VA levels spanning from near-normal to complete loss of sight[4-5].While vision tends to be reasonably consistent over several years for those with XLRS,there is documentation of a more rapid decline in later adulthood,specifically during the fourth and fifth decades,due to central retinal degeneration[5-7].Moreover,those with XLRS face an elevated risk for serious visual issues,such as retinal detachment,vitreous hemorrhages,and neovascular glaucoma[4].Female carriers could be found with slightly abnormal retinal changes without clinical symptoms[5].Even within the same family,the manifestation and progression of the condition can vary greatly,with individuals experiencing anything from nearly normal vision to complete loss of sight[8-9].Earlier investigations have revealed that retinoschisisrelated cystoid degeneration can impact multiple layers of the retina,beginning at the retinal nerve fiber zone and continuing to the nuclear stratum,with considerable fluctuation in the severity of the schisis[10-13].
