The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect...The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect more than 50million people worldwide.Neurodegenerative disorders are characterized by sundry factors and pathophysiological mechanisms that a re challenging to be fully profiled.Many of these rely on cell signaling pathways to preserve homeostasis,involving second messengers such as cyclic adenosine monophosphate (cAMP)and cyclic guanosine 3',5'-monophosphate(cGMP).Their ability to control the duration and amplitude of the signaling cascade is given by the presence of several common and uncommon effectors.Protein kinases A and G (PKA and PKG),phosphodiesterases (PDEs),and scaffold proteins are among them.展开更多
The synergy and complementary strengths between Macao and Hengqin can create an important channel for Chinese companies to internationalize.CHINESE enterprises have placed much emphasis on going global in recent years...The synergy and complementary strengths between Macao and Hengqin can create an important channel for Chinese companies to internationalize.CHINESE enterprises have placed much emphasis on going global in recent years,from traditional manufacturing giants to emerging tech unicorns,and from traditional sectors to emerging industries like electric vehicles,lithium batteries,and photovoltaic products.The enthusiasm to internationalize reached unprecedented levels in 2024.展开更多
Chengdu,a city rich in history and culture,is a beacon of China’s storied past embracing a distinct postmodern vibe.As an important hub along the ancient Silk Road,it has long been a meeting point for di!erent civili...Chengdu,a city rich in history and culture,is a beacon of China’s storied past embracing a distinct postmodern vibe.As an important hub along the ancient Silk Road,it has long been a meeting point for di!erent civilizations,where ideas and cultures have exchanged and thrived.Driven by the vision of a community with a shared future for mankind in recent years,Chengdu scholars and media have opened their arms to the world,engaging in multilingual storytelling.These efforts share the warmth and goodwill of a city consistently ranked one of the happiest in China.Through consistent efforts,new insights have emerged—ideas and aspirations intended to be shared with readers both at home and abroad.展开更多
As industrialization and informatization in China deeply integrate and the Internet of Things rapidly develops,industrial control systems are facing increasingly severe information security challenges.The industrial c...As industrialization and informatization in China deeply integrate and the Internet of Things rapidly develops,industrial control systems are facing increasingly severe information security challenges.The industrial control system of the gas extraction plant is characterized by numerous points and centralized operations,with a strong reliance on the system and stringent real-time requirements.展开更多
Open Gateway作为GSMA的倡议计划,通过统一API实现跨网络无缝访问,推动网络能力标准化开放,全球已有众多移动运营商参与其中,共同探索网络能力的商业变现。各大运营商对NaaS发展战略态度各异,但均在积极探索网络能力开放的新模式,以满...Open Gateway作为GSMA的倡议计划,通过统一API实现跨网络无缝访问,推动网络能力标准化开放,全球已有众多移动运营商参与其中,共同探索网络能力的商业变现。各大运营商对NaaS发展战略态度各异,但均在积极探索网络能力开放的新模式,以满足数字化转型需求。然而,运营商在开放网络能力方面仍面临跨境数据流动、网络安全和运营体系建设等诸多关键问题,商业模式、发展策略仍存在诸多问题需要决策。本文综合考虑国内外发展形势及实践经验,提出若干运营模式构想及运营发展建议,对运营商开展网络能力开放建设工作具有一定借鉴意义。展开更多
This ancient city has a history going back over 2,000 years.It has witnessed the fusion of multiple ethnic cultures including the Miao,Dong,and Han,and hosts a number of cultural heritage sites.THE old town of Zhenyua...This ancient city has a history going back over 2,000 years.It has witnessed the fusion of multiple ethnic cultures including the Miao,Dong,and Han,and hosts a number of cultural heritage sites.THE old town of Zhenyuan is located in Zhenyuan County,Qiandongnan Miao and Dong Autonomous Prefecture in southwest China’s Guizhou Province.Covering an area of just around three square kilometers,it sits on the banks of the Wuyang River and is surrounded by mountains.Zhenyuan has been a county for more than 2,281 years and was the prefectural capital during the Yuan(1271-1368)and Qing(1644-1911)dynasties.It is a multicultural region,with Miao,Dong,and other ethnic minorities making up nearly half of the population.展开更多
This work proposes an innovative approach to evaluate the functional characteristics of a heterogeneous underwater wireless acoustic sensor network(UWASN)using a stochastic model and the network connectivity criterion...This work proposes an innovative approach to evaluate the functional characteristics of a heterogeneous underwater wireless acoustic sensor network(UWASN)using a stochastic model and the network connectivity criterion.The connectivity criterion is probabilistic and considers inherently distinct groups of parameters:technical parameters that determine the network function at specific levels of the communication stack and physical parameters that describe the environment in the water area.The proposed approach enables researchers to evaluate the network characteristics in terms of energy efficiency and reliability while considering specific network and environmental parameters.Moreover,this approach is a simple and convenient tool for analyzing the effectiveness of protocols in various open systems interconnection model levels.It is possible to assess the potential capabilities of any protocol and include it in the proposed model.This work presents the results of modeling the critical characteristics of heterogeneous three-dimensional UWASNs of different scales consisting of stationary sensors and a wave glider as a mobile gateway,using specific protocols as examples.Several alternative routes for the wave glider are considered to optimize the network’s functional capabilities.Optimal trajectories of the wave glider’s movement have been determined in terms of ensuring the efficiency and reliability of the hybrid UWASN at various scales.In the context of the problem,an evaluation of different reference node placement was to ensure message transmission to a mobile gateway.The best location of reference nodes has been found.展开更多
With the vigorous development of Internet of Things(IoT)technology,the demand for communication and data exchange between different types of IoT devices is increasing day by day.To solve the problems of diversity and ...With the vigorous development of Internet of Things(IoT)technology,the demand for communication and data exchange between different types of IoT devices is increasing day by day.To solve the problems of diversity and complexity of communication protocols between devices,this paper proposes a design scheme of a multi-connector IoT central gateway based on Raspberry Pi and Docker.Through the research and application of related technologies,by integrating multiple communication interfaces and utilizing containerization technology,an efficient,flexible,and scalable IoT central gateway has been realized,which can support the connection and data interaction of multiple communication protocols and provide strong support for the stable operation and development of the IoT system.展开更多
文摘The umbrella term"neurodege ne rative disorders"(NDDs) refers to several conditions characterized by a progressive loss of structure and function of cells belonging to the nervous system.Such diseases affect more than 50million people worldwide.Neurodegenerative disorders are characterized by sundry factors and pathophysiological mechanisms that a re challenging to be fully profiled.Many of these rely on cell signaling pathways to preserve homeostasis,involving second messengers such as cyclic adenosine monophosphate (cAMP)and cyclic guanosine 3',5'-monophosphate(cGMP).Their ability to control the duration and amplitude of the signaling cascade is given by the presence of several common and uncommon effectors.Protein kinases A and G (PKA and PKG),phosphodiesterases (PDEs),and scaffold proteins are among them.
文摘The synergy and complementary strengths between Macao and Hengqin can create an important channel for Chinese companies to internationalize.CHINESE enterprises have placed much emphasis on going global in recent years,from traditional manufacturing giants to emerging tech unicorns,and from traditional sectors to emerging industries like electric vehicles,lithium batteries,and photovoltaic products.The enthusiasm to internationalize reached unprecedented levels in 2024.
文摘Chengdu,a city rich in history and culture,is a beacon of China’s storied past embracing a distinct postmodern vibe.As an important hub along the ancient Silk Road,it has long been a meeting point for di!erent civilizations,where ideas and cultures have exchanged and thrived.Driven by the vision of a community with a shared future for mankind in recent years,Chengdu scholars and media have opened their arms to the world,engaging in multilingual storytelling.These efforts share the warmth and goodwill of a city consistently ranked one of the happiest in China.Through consistent efforts,new insights have emerged—ideas and aspirations intended to be shared with readers both at home and abroad.
文摘As industrialization and informatization in China deeply integrate and the Internet of Things rapidly develops,industrial control systems are facing increasingly severe information security challenges.The industrial control system of the gas extraction plant is characterized by numerous points and centralized operations,with a strong reliance on the system and stringent real-time requirements.
文摘This ancient city has a history going back over 2,000 years.It has witnessed the fusion of multiple ethnic cultures including the Miao,Dong,and Han,and hosts a number of cultural heritage sites.THE old town of Zhenyuan is located in Zhenyuan County,Qiandongnan Miao and Dong Autonomous Prefecture in southwest China’s Guizhou Province.Covering an area of just around three square kilometers,it sits on the banks of the Wuyang River and is surrounded by mountains.Zhenyuan has been a county for more than 2,281 years and was the prefectural capital during the Yuan(1271-1368)and Qing(1644-1911)dynasties.It is a multicultural region,with Miao,Dong,and other ethnic minorities making up nearly half of the population.
基金partially funded by the Ministry of Science and Higher Education of the Russian Federation as a part of World-class Research Center Program:Advanced Digital Technologies(contract No.075-15-2022-312 dated 20 April 2022).
文摘This work proposes an innovative approach to evaluate the functional characteristics of a heterogeneous underwater wireless acoustic sensor network(UWASN)using a stochastic model and the network connectivity criterion.The connectivity criterion is probabilistic and considers inherently distinct groups of parameters:technical parameters that determine the network function at specific levels of the communication stack and physical parameters that describe the environment in the water area.The proposed approach enables researchers to evaluate the network characteristics in terms of energy efficiency and reliability while considering specific network and environmental parameters.Moreover,this approach is a simple and convenient tool for analyzing the effectiveness of protocols in various open systems interconnection model levels.It is possible to assess the potential capabilities of any protocol and include it in the proposed model.This work presents the results of modeling the critical characteristics of heterogeneous three-dimensional UWASNs of different scales consisting of stationary sensors and a wave glider as a mobile gateway,using specific protocols as examples.Several alternative routes for the wave glider are considered to optimize the network’s functional capabilities.Optimal trajectories of the wave glider’s movement have been determined in terms of ensuring the efficiency and reliability of the hybrid UWASN at various scales.In the context of the problem,an evaluation of different reference node placement was to ensure message transmission to a mobile gateway.The best location of reference nodes has been found.
文摘With the vigorous development of Internet of Things(IoT)technology,the demand for communication and data exchange between different types of IoT devices is increasing day by day.To solve the problems of diversity and complexity of communication protocols between devices,this paper proposes a design scheme of a multi-connector IoT central gateway based on Raspberry Pi and Docker.Through the research and application of related technologies,by integrating multiple communication interfaces and utilizing containerization technology,an efficient,flexible,and scalable IoT central gateway has been realized,which can support the connection and data interaction of multiple communication protocols and provide strong support for the stable operation and development of the IoT system.
