In view of the anisotropy,heterogeneity and stress-sensitive permeability in low permeability reservoirs,an analytical well test model was established by introducing the concept of permeability modulus.This model cons...In view of the anisotropy,heterogeneity and stress-sensitive permeability in low permeability reservoirs,an analytical well test model was established by introducing the concept of permeability modulus.This model considered the permeability stress-sensitivity,wellbore storage effect,and the skin effect.The perturbation technique and Laplace transformation were used to solve the mathematical model analytically in Laplace space,and the bottom-hole pressure type curves were plotted and analyzed in real space by using the Stehfest numerical inversion.展开更多
The vehicular sensor network (VSN) is an important part of intelligent transportation, which is used for real-timedetection and operation control of vehicles and real-time transmission of data and information. In the ...The vehicular sensor network (VSN) is an important part of intelligent transportation, which is used for real-timedetection and operation control of vehicles and real-time transmission of data and information. In the environmentofVSN, massive private data generated by vehicles are transmitted in open channels and used by other vehicle users,so it is crucial to maintain high transmission efficiency and high confidentiality of data. To deal with this problem, inthis paper, we propose a heterogeneous fault-tolerant aggregate signcryption scheme with an equality test (HFTASET).The scheme combines fault-tolerant and aggregate signcryption,whichnot onlymakes up for the deficiency oflow security of aggregate signature, but alsomakes up for the deficiency that aggregate signcryption cannot tolerateinvalid signature. The scheme supports one verification pass when all signcryptions are valid, and it supportsunbounded aggregation when the total number of signcryptions grows dynamically. In addition, this schemesupports heterogeneous equality test, and realizes the access control of private data in different cryptographicenvironments, so as to achieve flexibility in the application of our scheme and realize the function of quick searchof plaintext or ciphertext. Then, the security of HFTAS-ET is demonstrated by strict theoretical analysis. Finally, weconduct strict and standardized experimental operation and performance evaluation, which shows that the schemehas better performance.展开更多
The heterogeneity of coal was studied by mechanical tests. Probability plots of experimental data show that the mechanical parameters of heterogeneous coal follow a Weibull distribution. Based on elasto-plastic mechan...The heterogeneity of coal was studied by mechanical tests. Probability plots of experimental data show that the mechanical parameters of heterogeneous coal follow a Weibull distribution. Based on elasto-plastic mechanics and gas dynamics, the model of coupled gas flow＇ and deformation process of heterogeneous coal was presented and the effects of heterogeneity of coal on gas flow and failure of coal wcrc investigated. Major findings include： The effect of the heterogeneity of coal on gas flow and mechanical thilure of coal can be considered by the model in this paper. Failure of coal has a great effect on gas flow.展开更多
Slip transfer is influential in determining damage nucleation of polycrystalline material.The interactions between dislocations and grain boundaries(GBs)was investigated using in-situ tension test in a multi-direction...Slip transfer is influential in determining damage nucleation of polycrystalline material.The interactions between dislocations and grain boundaries(GBs)was investigated using in-situ tension test in a multi-directionally forged Mg-5.4Gd-1.8Y-1.5Zn(wt%)alloy.It was found that strain accommodation of individual grains by means of slip occurred more easily than slip transfer when several slip systems were operable.The basal-basal slip transfer occurred when the GB misorientation was smaller than 34.2°,whereas basal-pyramidal type took place when the crystallographic misorientation was larger than 48.8°.The product of Luster-Morris m factor and the sum of the Schmid factors of the two correlated slip systems indicated that the threshold for basal-basal slip transfer may exist,however,basal-pyramidal slip transfer shows no such threshold and is more complicated.These results presented here demonstrated that besides the geometrical alignment,the deformation details(such as the number of operable slip systems)and stress state in each individual grain must be considered.展开更多
The “National Institutes of Health” genetically heterogeneous (NIH-HS) rat stock was created in the 1980s through an eight-way cross of as much as possible separate inbred rat strains (i.e. the MR/N, WN/N, WKY/N, M5...The “National Institutes of Health” genetically heterogeneous (NIH-HS) rat stock was created in the 1980s through an eight-way cross of as much as possible separate inbred rat strains (i.e. the MR/N, WN/N, WKY/N, M520/N, F344/N, ACI/N, BN/SsN and BUF/N strains) which were readily available at that time. Hansen and Spuhler [1] developed a more naturalistic, genetically heterogeneous rat stock with the aim of optimizing the distribution of genotypic frequencies and recombination and under the hypothesis that the NIH-HS stock could yield a broad-range distribution of responses (broader than commonly used laboratory rat strains) to experimental conditions, and thus serve as a base population for selection studies. Along the last decade, in a series of studies we have phenotypically characterized the NIH-HS rat stock (a colony exists at our laboratory since 2004) for their anxiety/fearfulness profiles (using a battery of both unconditioned and conditioned tests/tasks), as well as regarding their stress-induced hormonal responses, coping style under inescapable stress and spatial learning ability. We have also compared the phenotypic profiles of NIH-HS rats with those of the low anxious RHA-I and the high anxious RLA-I rat strains. The NIH-HS rat stock is, as a population, a rather anxious type of rat, with predominantly reactive/passive coping style in unlearned and learned anxiety/fear tests, and elevated stress hormone responses (as well as enhanced “depressive” symptoms in the forced swimming test). Genetic studies currently under way have thus far revealed that the genetically heterogeneous NIH-HS rat stock constitutes a unique tool for fine mapping of QTL (for multiple behavioural and biological complex traits) to megabase resolution levels, thus enabling candidate gene identification. We give some examples of this in the present paper, while also highlighting that microarray gene expression studies reveal that HPA-axis- and prolactin-related genes (among others) in the amygdala appear to be related with (or associated to) the coping style and anxiety/fearfulness responses of NIH-HS rats.展开更多
This paper proposes a methodology to construct logs of rock strength from the cutting force signal recorded in scratch tests conducted in the ductile regime.The approach,which is based on the application of discrete w...This paper proposes a methodology to construct logs of rock strength from the cutting force signal recorded in scratch tests conducted in the ductile regime.The approach,which is based on the application of discrete wavelet transforms,recognizes the existence of two length scales[c and[r.The strength length scale[c represents the length over which it is meaningful to measure strength,while the repeatability length scale[r is related to the resolution at which the force signal must be observed to become insensitive to the stochastic micro-failure events triggered by the motion of the cutter.It is postulated that the original cutting force signal,assumed to be sampled at a high enough frequency,can be decomposed into a deterministic signal intrinsic to the rock and a stochastic one resulting from discrete rock failure events.The technique of multiresolution analysis based on the maximal overlap discrete wavelet transform is applied as a low-pass filter to the original cutting force signals so as to wipe out the high-frequency components associated with the stochastic rock failure events.A criterion to determine the optimum cutoff frequency of the low-pass filter and the corresponding repeatability length scale is discussed in terms of the correlation coefficients between different filtered signals.It is shown that the low-pass filtered signals obtained at the optimum cutoff frequency have two salient features:(i)repeatability over different tests conducted at the same depth of cut on the same sample,and(ii)variability along the cutting distance.The excellent repeatability reveals that the deterministic background trend of the original force signals is relevant to the rock strength property,and the variability of the background trend captures the spatial variation of the rock strength.展开更多
It is well-known that the power of Cochran’s Q test to assess the presence of heterogeneity among treatment effects in a clinical meta-analysis is low due to the small number of studies combined. Two modified tests (...It is well-known that the power of Cochran’s Q test to assess the presence of heterogeneity among treatment effects in a clinical meta-analysis is low due to the small number of studies combined. Two modified tests (PL1, PL2) were proposed by replacing the profile maximum likelihood estimator (PMLE) into the variance formula of logarithm of risk ratio in the standard chi-square test statistic for testing the null common risk ratios across all k studies (i = 1, L, k). The simply naive test (SIM) as another comparative candidate has considerably arisen. The performance of tests in terms of type I error rate under the null hypothesis and power of test under the random effects hypothesis was done via a simulation plan with various combinations of significance levels, numbers of studies, sample sizes in treatment and control arms, and true risk ratios as effect sizes of interest. The results indicated that for moderate to large study sizes (k?≥ 16)?in combination with moderate to large sample sizes?(?≥ 50), three tests (PL1, PL2, and Q) could control type I error rates in almost all situations. Two proposed tests (PL1, PL2) performed best with the highest power when?k?≥ 16?and moderate sample sizes (= 50,100);this finding was very useful to make a recommendation to use them in practical situations. Meanwhile, the standard Q test performed best when?k?≥ 16 and large sample sizes (≥ 500). Moreover, no tests were reasonable for small sample sizes (≤ 10), regardless of study size k. The simply naive test (SIM) is recommended to be adopted with high performance when k = 4 in combination with (≥ 500).展开更多
Aquifers derived from the crystalline basement rocks for parts of Sanga Local Government area of Kaduna State, Nigeria consist of clay, silt, sand, gravel and laterite materials which may be in various proportions. Us...Aquifers derived from the crystalline basement rocks for parts of Sanga Local Government area of Kaduna State, Nigeria consist of clay, silt, sand, gravel and laterite materials which may be in various proportions. Using Cooper-Jacobs non-equilibrium graphical method, the hydraulic properties were estimated from pumping test data of 18 boreholes. Conductivity varies from 1.02 × 10<sup>﹣2</sup> m/s to 4.07 × 10<sup>﹣2</sup> m/s and transmissivity varies from 1.14 × 10<sup>﹣1</sup> m<sup>2</sup>/s to 4.40 × 10<sup>﹣1</sup> m<sup>2</sup>/s. The values of specific capacity range between 1.03 × 10<sup>﹣1</sup> m<sup>2</sup>/s/m and 9.00 × 10<sup>﹣2</sup> m<sup>2</sup>/s/m, and these values indicate that the aquifers in the area have low to moderate ground water potentials. The low yield range of between 0.45 l/s and 1.00 l/s recorded in the area shows the heterogeneous and anisotropy nature of the basement aquifer system in terms of groundwater discharge. On the average, the boreholes assessed have potentials to sustain local to regional supply provided the best drilling method and materials are used and well completion properly done.展开更多
The genetically heterogeneous NIH-HS rat stock has been characterized by its response to anxiety- and fear-inducing situations, thus leading to the conclusion that they are a rather anxious and passive coping type of ...The genetically heterogeneous NIH-HS rat stock has been characterized by its response to anxiety- and fear-inducing situations, thus leading to the conclusion that they are a rather anxious and passive coping type of rats. Taking advantage of these profiles, and knowing that they show very poor performance in the two-way active (shuttle box) escape/avoidance task, we have tested NIH-HS rats (n = 80) in the forced swimming test (FST) as well as we have studied escape response deficits (i.e. response failures) of the same animals in the two-way shuttle box task. They were also tested for anxiety in the elevated zero-maze. The goal of such a study was that of investigating whether there are associations or relationships among helplessness-like or passive coping responses between both models of depression, i.e. the FST and the helplessness-like escape deficits in the shuttle box task. The results for the first time show associations among responses from both depression models and that selecting rats for displaying extreme (active or passive) responses in one of the models predict in a coherent manner (according to the hypothesis) their behaviour in the other model. These findings are discussed in the context of the concurrent validity of both models of depression as well as concerning the possible relevance of NIH-HS rats as a tool for future studies on this field.展开更多
基金support from the National 973 Program (Grant No. 2006CB705808)PetroChina Young and Middle Aged People Innovation Fund (Grant No. 07E1016)+1 种基金PetroChina Science & Technology Innovation Fund (Grant No. 2008D-5006-02-09)Science & Technology Innovation Fund of Southwest Petroleum University (Grant No. 2007XJZ010)
文摘In view of the anisotropy,heterogeneity and stress-sensitive permeability in low permeability reservoirs,an analytical well test model was established by introducing the concept of permeability modulus.This model considered the permeability stress-sensitivity,wellbore storage effect,and the skin effect.The perturbation technique and Laplace transformation were used to solve the mathematical model analytically in Laplace space,and the bottom-hole pressure type curves were plotted and analyzed in real space by using the Stehfest numerical inversion.
基金supported in part by the Open Fund of Advanced Cryptography and System Security Key Laboratory of Sichuan Province under Grant SKLACSS-202102in part by the Intelligent Terminal Key Laboratory of Sichuan Province under Grant SCITLAB-1019.
文摘The vehicular sensor network (VSN) is an important part of intelligent transportation, which is used for real-timedetection and operation control of vehicles and real-time transmission of data and information. In the environmentofVSN, massive private data generated by vehicles are transmitted in open channels and used by other vehicle users,so it is crucial to maintain high transmission efficiency and high confidentiality of data. To deal with this problem, inthis paper, we propose a heterogeneous fault-tolerant aggregate signcryption scheme with an equality test (HFTASET).The scheme combines fault-tolerant and aggregate signcryption,whichnot onlymakes up for the deficiency oflow security of aggregate signature, but alsomakes up for the deficiency that aggregate signcryption cannot tolerateinvalid signature. The scheme supports one verification pass when all signcryptions are valid, and it supportsunbounded aggregation when the total number of signcryptions grows dynamically. In addition, this schemesupports heterogeneous equality test, and realizes the access control of private data in different cryptographicenvironments, so as to achieve flexibility in the application of our scheme and realize the function of quick searchof plaintext or ciphertext. Then, the security of HFTAS-ET is demonstrated by strict theoretical analysis. Finally, weconduct strict and standardized experimental operation and performance evaluation, which shows that the schemehas better performance.
基金Supported by the Key National Natural Science Foundation of China （50434020） the Natural Science Foundation of Hebei Province, China （E2010000872, Z2009315）
文摘The heterogeneity of coal was studied by mechanical tests. Probability plots of experimental data show that the mechanical parameters of heterogeneous coal follow a Weibull distribution. Based on elasto-plastic mechanics and gas dynamics, the model of coupled gas flow＇ and deformation process of heterogeneous coal was presented and the effects of heterogeneity of coal on gas flow and failure of coal wcrc investigated. Major findings include： The effect of the heterogeneity of coal on gas flow and mechanical thilure of coal can be considered by the model in this paper. Failure of coal has a great effect on gas flow.
基金The authors acknowledge the funding support from National Natural Science Foundation of China via grant 51775135.
文摘Slip transfer is influential in determining damage nucleation of polycrystalline material.The interactions between dislocations and grain boundaries(GBs)was investigated using in-situ tension test in a multi-directionally forged Mg-5.4Gd-1.8Y-1.5Zn(wt%)alloy.It was found that strain accommodation of individual grains by means of slip occurred more easily than slip transfer when several slip systems were operable.The basal-basal slip transfer occurred when the GB misorientation was smaller than 34.2°,whereas basal-pyramidal type took place when the crystallographic misorientation was larger than 48.8°.The product of Luster-Morris m factor and the sum of the Schmid factors of the two correlated slip systems indicated that the threshold for basal-basal slip transfer may exist,however,basal-pyramidal slip transfer shows no such threshold and is more complicated.These results presented here demonstrated that besides the geometrical alignment,the deformation details(such as the number of operable slip systems)and stress state in each individual grain must be considered.
基金grants for the MICINN (PSI2009-10532) “Fundació La Maratò TV3” (ref. 092630/31) 2009SGR-0051 and the European pro- ject/consortium “EURATRANS” (grant agreement HEALTH-F4- 2010-241504)
文摘The “National Institutes of Health” genetically heterogeneous (NIH-HS) rat stock was created in the 1980s through an eight-way cross of as much as possible separate inbred rat strains (i.e. the MR/N, WN/N, WKY/N, M520/N, F344/N, ACI/N, BN/SsN and BUF/N strains) which were readily available at that time. Hansen and Spuhler [1] developed a more naturalistic, genetically heterogeneous rat stock with the aim of optimizing the distribution of genotypic frequencies and recombination and under the hypothesis that the NIH-HS stock could yield a broad-range distribution of responses (broader than commonly used laboratory rat strains) to experimental conditions, and thus serve as a base population for selection studies. Along the last decade, in a series of studies we have phenotypically characterized the NIH-HS rat stock (a colony exists at our laboratory since 2004) for their anxiety/fearfulness profiles (using a battery of both unconditioned and conditioned tests/tasks), as well as regarding their stress-induced hormonal responses, coping style under inescapable stress and spatial learning ability. We have also compared the phenotypic profiles of NIH-HS rats with those of the low anxious RHA-I and the high anxious RLA-I rat strains. The NIH-HS rat stock is, as a population, a rather anxious type of rat, with predominantly reactive/passive coping style in unlearned and learned anxiety/fear tests, and elevated stress hormone responses (as well as enhanced “depressive” symptoms in the forced swimming test). Genetic studies currently under way have thus far revealed that the genetically heterogeneous NIH-HS rat stock constitutes a unique tool for fine mapping of QTL (for multiple behavioural and biological complex traits) to megabase resolution levels, thus enabling candidate gene identification. We give some examples of this in the present paper, while also highlighting that microarray gene expression studies reveal that HPA-axis- and prolactin-related genes (among others) in the amygdala appear to be related with (or associated to) the coping style and anxiety/fearfulness responses of NIH-HS rats.
基金provided by the National Science Foundation of USA(Grant No.1742823)。
文摘This paper proposes a methodology to construct logs of rock strength from the cutting force signal recorded in scratch tests conducted in the ductile regime.The approach,which is based on the application of discrete wavelet transforms,recognizes the existence of two length scales[c and[r.The strength length scale[c represents the length over which it is meaningful to measure strength,while the repeatability length scale[r is related to the resolution at which the force signal must be observed to become insensitive to the stochastic micro-failure events triggered by the motion of the cutter.It is postulated that the original cutting force signal,assumed to be sampled at a high enough frequency,can be decomposed into a deterministic signal intrinsic to the rock and a stochastic one resulting from discrete rock failure events.The technique of multiresolution analysis based on the maximal overlap discrete wavelet transform is applied as a low-pass filter to the original cutting force signals so as to wipe out the high-frequency components associated with the stochastic rock failure events.A criterion to determine the optimum cutoff frequency of the low-pass filter and the corresponding repeatability length scale is discussed in terms of the correlation coefficients between different filtered signals.It is shown that the low-pass filtered signals obtained at the optimum cutoff frequency have two salient features:(i)repeatability over different tests conducted at the same depth of cut on the same sample,and(ii)variability along the cutting distance.The excellent repeatability reveals that the deterministic background trend of the original force signals is relevant to the rock strength property,and the variability of the background trend captures the spatial variation of the rock strength.
文摘It is well-known that the power of Cochran’s Q test to assess the presence of heterogeneity among treatment effects in a clinical meta-analysis is low due to the small number of studies combined. Two modified tests (PL1, PL2) were proposed by replacing the profile maximum likelihood estimator (PMLE) into the variance formula of logarithm of risk ratio in the standard chi-square test statistic for testing the null common risk ratios across all k studies (i = 1, L, k). The simply naive test (SIM) as another comparative candidate has considerably arisen. The performance of tests in terms of type I error rate under the null hypothesis and power of test under the random effects hypothesis was done via a simulation plan with various combinations of significance levels, numbers of studies, sample sizes in treatment and control arms, and true risk ratios as effect sizes of interest. The results indicated that for moderate to large study sizes (k?≥ 16)?in combination with moderate to large sample sizes?(?≥ 50), three tests (PL1, PL2, and Q) could control type I error rates in almost all situations. Two proposed tests (PL1, PL2) performed best with the highest power when?k?≥ 16?and moderate sample sizes (= 50,100);this finding was very useful to make a recommendation to use them in practical situations. Meanwhile, the standard Q test performed best when?k?≥ 16 and large sample sizes (≥ 500). Moreover, no tests were reasonable for small sample sizes (≤ 10), regardless of study size k. The simply naive test (SIM) is recommended to be adopted with high performance when k = 4 in combination with (≥ 500).
文摘Aquifers derived from the crystalline basement rocks for parts of Sanga Local Government area of Kaduna State, Nigeria consist of clay, silt, sand, gravel and laterite materials which may be in various proportions. Using Cooper-Jacobs non-equilibrium graphical method, the hydraulic properties were estimated from pumping test data of 18 boreholes. Conductivity varies from 1.02 × 10<sup>﹣2</sup> m/s to 4.07 × 10<sup>﹣2</sup> m/s and transmissivity varies from 1.14 × 10<sup>﹣1</sup> m<sup>2</sup>/s to 4.40 × 10<sup>﹣1</sup> m<sup>2</sup>/s. The values of specific capacity range between 1.03 × 10<sup>﹣1</sup> m<sup>2</sup>/s/m and 9.00 × 10<sup>﹣2</sup> m<sup>2</sup>/s/m, and these values indicate that the aquifers in the area have low to moderate ground water potentials. The low yield range of between 0.45 l/s and 1.00 l/s recorded in the area shows the heterogeneous and anisotropy nature of the basement aquifer system in terms of groundwater discharge. On the average, the boreholes assessed have potentials to sustain local to regional supply provided the best drilling method and materials are used and well completion properly done.
基金Supported by grants for the MICINN(SAF2009-10532),“Fundacio La Marato TV3”(ref.092630/31),2009SGR-0051EURATRANS consortium(grant agreement HEALTH-F4-2010-241504)the Welcome Trust(UK).C.M-C is recipient of a FPI(2010,MICINN)PhD fellowship.
文摘The genetically heterogeneous NIH-HS rat stock has been characterized by its response to anxiety- and fear-inducing situations, thus leading to the conclusion that they are a rather anxious and passive coping type of rats. Taking advantage of these profiles, and knowing that they show very poor performance in the two-way active (shuttle box) escape/avoidance task, we have tested NIH-HS rats (n = 80) in the forced swimming test (FST) as well as we have studied escape response deficits (i.e. response failures) of the same animals in the two-way shuttle box task. They were also tested for anxiety in the elevated zero-maze. The goal of such a study was that of investigating whether there are associations or relationships among helplessness-like or passive coping responses between both models of depression, i.e. the FST and the helplessness-like escape deficits in the shuttle box task. The results for the first time show associations among responses from both depression models and that selecting rats for displaying extreme (active or passive) responses in one of the models predict in a coherent manner (according to the hypothesis) their behaviour in the other model. These findings are discussed in the context of the concurrent validity of both models of depression as well as concerning the possible relevance of NIH-HS rats as a tool for future studies on this field.
