Sand production and high water content in oil wells are two major challenges that restrict high and stable production in loose sandstone reservoirs.In this paper,nano SiO_(2),coupling agent triethoxysilane,phenolic re...Sand production and high water content in oil wells are two major challenges that restrict high and stable production in loose sandstone reservoirs.In this paper,nano SiO_(2),coupling agent triethoxysilane,phenolic resin and n-octanol were used to synthesize the main agent SCA-2.Hexamethylenetetramine and vinyl carbonate were selected to prepare the curing agent YGA-1,which was then compounded with SCA-2 to develop a sand fixation and water plugging system.Firstly,single-factor experiments were conducted to determine the optimal concentrations of SCA-2 and YGA-1,subsequently,the system’s sand fixation and water blocking performance were evaluated.Finally,a pilot test was carried out in the mining site.Experimental results showed that the optimal formula composition of the system was 10%SCA-2+5%YGA-1.The gelation time of the system was 180 minutes and the viscosity after gelation could reach 108.4 mPa·s.When the dosage of the drug system was 0.6 PV,the sand production rate remained below 0.08%.Dual-tube parallel experiments showed that the sand fixation and water plugging system had a water flow channel plugging rate of 87.5%,while the oil flow channel plugging rate was only 11.3%,indicating minimal damage to the oil-bearing reservoir.The field test showed that after the measures taken in Well M of X oilfield,the sand free oil recovery period exceeded 360 days,the water content decreased by 5.0%and the cumulative oil production increased by 7092 m^(3).This study provides new ideas for efficient development of loose sandstone reservoirs.展开更多
A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and...A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and development of the NMI model and then emphasize that the NMI model represents a new tool for identifying the basic physics of how climate change influences mid-to-high latitude weather extremes.The building of the NMI model took place over three main periods.In the 1990s,a nonlinear Schr?dinger(NLS)equation model was presented to describe atmospheric blocking as a wave packet;however,it could not depict the lifetime(10-20 days)of atmospheric blocking.In the 2000s,we proposed an NMI model of atmospheric blocking in a uniform basic flow by making a scale-separation assumption and deriving an eddyforced NLS equation.This model succeeded in describing the life cycle of atmospheric blocking.In the 2020s,the NMI model was extended to include the impact of a changing climate mainly by altering the basic zonal winds and the magnitude of the meridional background potential vorticity gradient(PVy).Model results show that when PVy is smaller,blocking has a weaker dispersion and a stronger nonlinearity,so blocking can be more persistent and have a larger zonal scale and weaker eastward movement,thus favoring stronger weather extremes.However,when PVy is much smaller and below a critical threshold under much stronger winter Arctic warming of global warming,atmospheric blocking becomes locally less persistent and shows a much stronger westward movement,which acts to inhibit local cold extremes.Such a case does not happen in summer under global warming because PVy fails to fall below the critical threshold.Thus,our theory indicates that global warming can render summer-blocking anticyclones and mid-to-high latitude heatwaves more persistent,intense,and widespread.展开更多
The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical m...The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical model height.The Taguchi method was employed to establish the correlations between process parameter combinations and multi-objective characterization of metal deposition morphology(height error and roughness).Results show that using the signal-to-noise ratio and grey relational analysis,the optimal parameter combination for multi-layer and multi-pass deposition is determined as follows:laser power of 800 W,powder feeding rate of 0.3 r/min,step distance of 1.6 mm,and scanning speed of 20 mm/s.Subsequently,a Genetic Bayesian-back propagation(GB-BP)network is constructed to predict multi-objective responses.Compared with the traditional back propagation network,the GB-back propagation network improves the prediction accuracy of height error and surface roughness by 43.14%and 71.43%,respectively.This network can accurately predict the multi-objective characterization of morphological quality of multi-layer and multi-pass metal deposited parts.展开更多
Three extreme cold events occurred in eastern Asia in January 2016,January 2021,and December 2023.As important factors in atmospheric circulation anomalies,the Blocking High and East Asian Trough(BH-ET)structure playe...Three extreme cold events occurred in eastern Asia in January 2016,January 2021,and December 2023.As important factors in atmospheric circulation anomalies,the Blocking High and East Asian Trough(BH-ET)structure played key roles during these three extreme cold wave events.Among these two dynamic patterns,the BH affected the development of the cold waves in two different ways:(1)before the cold waves in 2016 and 2023,the BH pushed the cold air southward,resulting in a slow and gradual cooling,with a cooling rate(CR)in eastern Asia of 1.34℃d^(-1)and 1.2℃d^(-1),respectively,and(2)in January 2021,the sudden collapse of BH caused the cold air to rapidly attack mid-latitude regions,with a CR of 1.87℃d^(-1).In terms of the spatial CR,the temperature drop in 2021 occurred 38.8%and 55%faster than those in 2016 and 2023,respectively.At the same time,the ET influences the wind direction of cold waves by modulating the pressure gradient.Before the cold waves occurred,the meridional wind field near the ET showed negative values,forming northwesterly or northeasterly winds,which continued to affect the southern part of East Asia.The meridional wind in January 2021 was stronger than those in 2016 and 2023,which is thought to be the reason for the strength of the 2021 cold wave.Finally,results from the temperature Empirical Orthogonal Function(EOF)analysis from 1980-2023 verify an obvious BH-ET structure in the three cold wave events,which suggests that this particular climatological state provides a climatic background for the occurrence of cold waves.展开更多
Seawater is the most abundant source of molecular hydrogen.Utilizing the hydrogen reserves present in the seawater may inaugurate innovative strategies aimed at advancing sustainable energy and environmental preservat...Seawater is the most abundant source of molecular hydrogen.Utilizing the hydrogen reserves present in the seawater may inaugurate innovative strategies aimed at advancing sustainable energy and environmental preservation endeavors in the future.Recently,there has been a surge in study in the field addressing the production of hydrogen through the electrochemical seawater splitting.However,the performance and durability of the electrode have limitations due to the fact that there are a few challenges that need to be addressed in order to make the technology suitable for the industrial purpose.The active site blockage caused by chloride ions that are prevalent in seawater and chloride corrosion is the most significant issue;it has a negative impact on both the activity and the durability of the anode component.Addressing this particular issue is of upmost importance in the seawater splitting area.This review concentrates on the newly developed materials and techniques for inhibiting chloride ions by blocking the active sites,simultaneously preventing the chloride corrosion.It is anticipated that the concept will be advantageous for a large audience and will inspire researchers to study on this particular area of concern.展开更多
White light illumination is essential in daily life,however,the substantial amount of blue light it contains can damage human eyes.Therefore,it is important to block this high-energy blue light to protect visual healt...White light illumination is essential in daily life,however,the substantial amount of blue light it contains can damage human eyes.Therefore,it is important to block this high-energy blue light to protect visual health.In this study,yellow-emitting carbon dots(CDs)with a quantum yield exceeding 94%were synthesized using citric acid and urea.These CDs effectively absorb blue light.By incorporating them into polystyrene,multiple films termed CDs-based blue light blocking films(CBFs)were developed,each offering different levels of blue light absorption.These CBFs exhibited excellent transparency and efficient blue light filtering capabilities.This study highlights the potential of high quantum yield CDs,which specifically absorb blue light,as foundational materials for developing light-blocking solutions against highenergy short-wavelength light.展开更多
In this paper,we present a necessary and sufficient condition for hyponormal block Toeplitz operators T on the vector-valued weighted Bergman space with symbolsΦ(z)=G^(*)(z)+F(z),where F(z)=∑^(N)_(i)=1 A_(i)z^(i)and...In this paper,we present a necessary and sufficient condition for hyponormal block Toeplitz operators T on the vector-valued weighted Bergman space with symbolsΦ(z)=G^(*)(z)+F(z),where F(z)=∑^(N)_(i)=1 A_(i)z^(i)and G(z)=∑^(N)_(i)=1 A_(−i)z^(i),A_(i)ae culants.展开更多
This paper investigates a distributed heterogeneous hybrid blocking flow-shop scheduling problem(DHHBFSP)designed to minimize the total tardiness and total energy consumption simultaneously,and proposes an improved pr...This paper investigates a distributed heterogeneous hybrid blocking flow-shop scheduling problem(DHHBFSP)designed to minimize the total tardiness and total energy consumption simultaneously,and proposes an improved proximal policy optimization(IPPO)method to make real-time decisions for the DHHBFSP.A multi-objective Markov decision process is modeled for the DHHBFSP,where the reward function is represented by a vector with dynamic weights instead of the common objectiverelated scalar value.A factory agent(FA)is formulated for each factory to select unscheduled jobs and is trained by the proposed IPPO to improve the decision quality.Multiple FAs work asynchronously to allocate jobs that arrive randomly at the shop.A two-stage training strategy is introduced in the IPPO,which learns from both single-and dual-policy data for better data utilization.The proposed IPPO is tested on randomly generated instances and compared with variants of the basic proximal policy optimization(PPO),dispatch rules,multi-objective metaheuristics,and multi-agent reinforcement learning methods.Extensive experimental results suggest that the proposed strategies offer significant improvements to the basic PPO,and the proposed IPPO outperforms the state-of-the-art scheduling methods in both convergence and solution quality.展开更多
BACKGROUND A major cause of mortality in the coronavirus disease 2019(COVID-19)pandemic was acute respiratory distress syndrome(ARDS).Currently,moderate to severe ARDS induced by COVID-19(COVID ARDS)and other viral an...BACKGROUND A major cause of mortality in the coronavirus disease 2019(COVID-19)pandemic was acute respiratory distress syndrome(ARDS).Currently,moderate to severe ARDS induced by COVID-19(COVID ARDS)and other viral and non-viral etiologies are treated by traditional ARDS protocols that recommend 12-16 hours of prone position ventilation(PPV)with neuromuscular blocking agents(NMBA)and a trial of inhaled vasodilators(IVd)if oxygenation does not improve.However,debate on the efficacy of adjuncts to PPV and low tidal volume ventilation persists and evidence about the benefits of IVd/NMBA in COVID ARDS is sparse.In our multi-center retrospective review,we evaluated the impact of PPV,IVd,and NMBA on outcomes and lung mechanics in COVID ARDS patients with moderate to severe ARDS.AIM To evaluate the impact of PPV used alone or in combination with pulmonary IVd and/or NMBA in mechanically ventilated patients with moderate to severe ARDS during the COVID-19 pandemic.METHODS A retrospective study at two tertiary academic medical centers compared outcomes between COVID ARDS patients receiving PPV and patients in the supine position.PPV patients were divided based on concurrent use of ARDS adjunct therapies resulting in four subgroups:(1)PPV alone;(2)PPV and IVd;(3)PPV and NMBA;and(4)PPV,IVd,and NMBA.Primary outcomes were hospital and intensive care unit(ICU)length of stay(LOS),mortality,and venovenous extracorporeal membrane oxygenation(VV-ECMO)status.Secondary outcomes included changes in lung mechanics at 24-hour intervals for 7 days.RESULTS Total 114 patients were included in this study.Baseline respiratory parameters and Sequential Organ Failure Assessment scores were significantly worse in the PPV group.ICU LOS and LOS were significantly longer for patients who were proned,but no mortality benefit or difference in VV-ECMO status was found.Among the subgroups,no difference in primary outcomes were found.In the secondary analysis,PPV was associated with a significant improvement in arterial oxygen partial pressure(PaO_(2))/fractional inspired oxygen(FiO_(2))(P/F)ratio from day 1 to day 4(P<0.05)and higher driving pressures day 5 to day 7(P<0.05).The combination of PPV and IVd together resulted in improvements in P/F ratio from day 1 to day 7 and plateau pressure on day 4 and day 6(P<0.05).PPV with NMBA was not associated with improvements in any of the secondary outcomes.The use of all three rescue therapies together resulted in improvements in lung compliance on day 2(P<0.05)but no other improvements.CONCLUSION In mechanically ventilated patients diagnosed with moderate to severe COVID ARDS,PPV and PPV with the addition of IVd produced a significant and sustained increase in P/F ratio.The combination of PPV,IVd and NMBA improved compliance however this did not reach significance.Mortality and LOS did not improve with adjunct therapies.Further research is warranted to determine the efficacy of these therapies alone and in combination in the treatment of COVID ARDS.展开更多
When patients initially present with atrial fibrillation along with an enlarged heart and heart failure, followed by atrioventricular block, it's essential to consider genetic factors.^([1])Genetic testing can off...When patients initially present with atrial fibrillation along with an enlarged heart and heart failure, followed by atrioventricular block, it's essential to consider genetic factors.^([1])Genetic testing can offer crucial diagnostic evidence, aiding in prognosis assessment and the adoption of appropriate treatment strategies.展开更多
Nanoporous polymers are extensively coated on various substrates to deliver optical,permselective,or other functions.However,it remains desired to fast produce uniform nanoporous polymer coatings on substrates with co...Nanoporous polymers are extensively coated on various substrates to deliver optical,permselective,or other functions.However,it remains desired to fast produce uniform nanoporous polymer coatings on substrates with complex surfaces.Herein,by manipulating the interactions between block copolymers and selective solvents,we prepare repairable nanoporous polymers on arbitrary substrates.This is realized by an extremely simple sequential coating process:sequential coating of block copolymers and their swelling agents on substrate surfaces.The swelling agents are comprised of two solvents that swell the constituent blocks of the copolymers to different degrees,rapidly producing polymer coatings with uniform,interconnected,sub-50 nm pores.This sequential coating process is able to conformally build nanoporous polymers on nonplanar substrates with large lateral sizes and complex surface features,and also to in situ repair defects arising during usages.We further demonstrate that the nanoporous coatings show excellent antireflective and membrane separation performances.This sequential coating process is dictated by polymer–solvent interactions,and is expected to find applications in diverse fields for its simplicity,adaptability,and the capability to produce well-defined nanoporosities.展开更多
The diagnostic efficacy of contemporary bioimaging technologies remains constrained by inherent limitations of conventional imaging agents,including suboptimal sensitivity,off-target biodistribution,and inherent cytot...The diagnostic efficacy of contemporary bioimaging technologies remains constrained by inherent limitations of conventional imaging agents,including suboptimal sensitivity,off-target biodistribution,and inherent cytotoxicity.These limitations have catalyzed the development of intelligent stimuli-responsive block copolymers-based bioimaging agents,which was engineered to dynamically respond to endogenous biochemical cues(e.g.,p H gradients,redox potential,enzyme activity,hypoxia environment) or exogenous physical triggers(e.g.,photoirradiation,thermal gradients,ultrasound(US)/magnetic stimuli).Through spatiotemporally controlled structural transformations,stimuli-responsive block copolymers enable precise contrast targeting,activatable signal amplification,and theranostic integration,thereby substantially enhancing signal-to-noise ratios of bioimaging and diagnostic specificity.Hence,this mini-review systematically examines molecular engineering principles for designing p H-,redox-,enzyme-,light-,thermo-,and US/magnetic-responsive polymers,with emphasis on structure-property relationships governing imaging performance modulation.Furthermore,we critically analyze emerging strategies for optical imaging,US synergies,and magnetic resonance imaging(MRI).Multimodal bioimaging has also been elaborated,which could overcome the inherent trade-offs between resolution,penetration depth,and functional specificity in single-modal approaches.By elucidating mechanistic insights and translational challenges,this mini-review aims to establish a design framework of stimuli-responsive block copolymersbased for high fidelity bioimaging agents and accelerate their clinical translation in precise diagnosis and therapy.展开更多
Switchable polymerization is emerging as a powerful tool to construct block copolymers directly from mixtures of monomers.However,current achievements typically iterate between two polymerization cycles to afford prod...Switchable polymerization is emerging as a powerful tool to construct block copolymers directly from mixtures of monomers.However,current achievements typically iterate between two polymerization cycles to afford products with fixed sequences and compositions.Herein,we report the triethylborane/1,8-diazabicyclo[5.4.0]undec-7-ene(Et_3B/DBU)pair-mediated four-component switchable polymerization of propylene oxide(PO),CO_(2),phthalic anhydride(PA),and racemic lactide(rac-LA),which enables the on-demand synthesis of four different block copolymers,i.e.,poly(propylene phthalate)-b-polylactide(PPE-b-PLA),PPE-b-PLA-b-poly(propylene carbonate)(PPC),PPE-b-PPC-b-PLA,and PPE-b-PPCb-poly(propylene oxide)(PPO),through rationally modulating the Lewis pair(LP)ratio.Core to this protocol is that increasing the loading of Et_(3)B accelerates the ring-opening of PO while impeding the reactivity of rac-LA,thus allowing for fine-tuning of the thermodynamic and kinetic of the switchable polymerization.Therefore,the four polymerization cycles involving PO/PA ring-opening copolymerization(ROCOP),PO/CO_(2) ROCOP,rac-LA ring-opening polymerization(ROP),and PO ROP can be connected and discriminated in precisely programmed manners.展开更多
This paper presents a novel artificial intelligence(AI)-assisted two-stage method for optimising rock slope stability by integrating advanced 3D modelling with rock support design,aiming at minimising risks,material u...This paper presents a novel artificial intelligence(AI)-assisted two-stage method for optimising rock slope stability by integrating advanced 3D modelling with rock support design,aiming at minimising risks,material usage,and costs.In the first stage,an extended key block analysis identifies key blocks and key block groups,accounting for progressive failure and force interactions.The second stage uses AI algorithms to optimise rockbolting design,balancing stability,cost,and material use.The most efficient algorithms include the multi-objective tree-structured Parzen estimator(MOTPE)and non-dominated sorting genetic algorithms(NSGA-II and NSGA-III).Applied to the Larvik rock slope,the optimised solution uses 18 pre-tensioned cablebolts,providing 13.2 MN of active force and achieving a factor of safety of 1.31 while reducing the average anchorage length by approximately 16%compared to traditional design.The AI-assisted approach also reduces computation time by over 90%compared to Quasi-Monte Carlo(QMC)methods,demonstrating its efficiency for small-scale civil engineering projects and large-scale mining operations.The developed tool is practical,compatible with Building Information Modelling(BIM),and ready for engineering implementation,supporting sustainable and cost-effective rock slope stabilisation.While the method is largely automated,professional judgement remains crucial for verifying ground conditions and selecting the final solution.Future work will focus on integrating data uncertainties,addressing complex block deformation mechanisms,refining optimisation objectives,and improving the performance of multi-objective optimisation for slope rockboling applications to further enhance the method's versatility.展开更多
Waste graphitization cathode carbon blocks are a type of hazardous solid waste generated during the aluminum electrolysis process,and their proper disposal is a key step in the resource utilization of discarded graphi...Waste graphitization cathode carbon blocks are a type of hazardous solid waste generated during the aluminum electrolysis process,and their proper disposal is a key step in the resource utilization of discarded graphite.This study utilizes the porous“defect advantage”of a cathode carbon block matrix to prepare silicon-doped and asphalt-coated detoxified and purified waste graphitization cathode carbon blocks for use as high-performance silicon/carbon composite anode materials.The results show that the uniformly silicondoped silicon/carbon composite material features a unique amorphous carbon-encapsulated“locked silicon”structure,which effectively addresses issues such as cathode volume expansion,excessive growth of the solid electrolyte interphase(SEI)film,and poor electrical contact between active materials.Consequently,electrochemical performance is enhanced.After assembly in a half-cell,the PSCC/10%Si@C(purified waste graphitization cathode carbon/10%Si@C)material exhibits optimal electrochemical stability,with an initial charging specific capacity of 514.5 mAh/g at 0.1 C(1 C=170 mA/g)and a capacity retention rate of 95.1%after 100 cycles.At a charge rate of 2.0 C,a specific capacity of 216.9 mAh/g is achieved.This technology provides a new pathway for the economical and high-value utilization of waste cathode carbon blocks and the development of low-cost,high-performance anode materials.展开更多
Star-shaped six-arm polymers with hexaaza[2_(6)]orthoparacyclophane core and arms of block copolymers of poly-2-ethyl-5,6-dihydrooxazine with poly-2-isopropyl-5,6-dihydrooxazine were synthesized successfully using cat...Star-shaped six-arm polymers with hexaaza[2_(6)]orthoparacyclophane core and arms of block copolymers of poly-2-ethyl-5,6-dihydrooxazine with poly-2-isopropyl-5,6-dihydrooxazine were synthesized successfully using cationic ring-opening polymerization.The ratio of blocks,the order of their attachment to the core,and arm length were varied.Conformation of synthesized stars was determined by methods of molecular hydrodynamics and optics.It has been shown that star-shaped molecules were characterized by high intramolecular density,and the arm folding increased with their lengthening.The influence of the structure of block copolymers and their molar mass on the critical micelle concentration has been established.Complexes of synthesized star-shaped block copolymers with curcumin were obtained and the efficient binding of curcumin to polymer molecules was demonstrated.The behavior of the aqueous solutions of the prepared polymer stars and their complexes with curcumin was investigated by light scattering and turbidimetry methods.The influence of the structure and molar mass of star polymers on their thermoresponsiveness and the phase separation temperatures in aqueous solutions was analyzed.A slight increase in the phase separation temperature was found on passage from polymer solutions to solutions of polymer complexes with hydrophobic curcumin.展开更多
Some novel techniques of computational fluid dynamics are used to establish a mathematical model for the open diversion channel with two embankments in river blocking.The technique of boundary fitted coordinate syste...Some novel techniques of computational fluid dynamics are used to establish a mathematical model for the open diversion channel with two embankments in river blocking.The technique of boundary fitted coordinate system is used to overcome the difficulties resulting from the complicated shapes of natural river boundaries;the method of alternating direction implicit finite difference scheme is used to solve the partial differential equations in the transformed plane;and the technique of moving boundary is used to deal with the river bed exposed to water surface.This model has been used to predict the flow characteristics in the blocking of the Yangtz river in the Three Gorge Project (TGP).Comparison between the computed and experimental data shows a satisfactory agreement.展开更多
Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan （龙眼, Extra） acupoint. M...Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan （龙眼, Extra） acupoint. Methods According to the random mumber table, 104 cases of herpes zoster were randomized into an observation group and a control group, 52 cases in each one. In the observation group, the blocking method was used at the starting site and the ending site of herpetic zone, the surrounding needling method was applied toward the center of the painful zone, with horizontal needling technique; and the local pricking and cupping methods as well as the bloodletting at Longyan （Extra） acupoint were adopted. In the control group, Jiáj （夹脊 EX-B 2） at the corresponding affected nerve segments and the local Ashi points were selected and stimulated with electroacupuncture. The visual analogue scale （VAS） was adopted to determine the analgesic effect 20 min, 1, 6, 12, 24 and 48 h after treatment separately in each group. Results The onset time of analgesic effect in the observation group was shorter than that in the control group and the efficacy time of duration was longer than that in the control group （all P0.05）. The analgesic effect and the result of comprehensive efficacy assessment were superior to those of the control group （both P0.05）. Conclusion The comprehensive therapy of blocking, surrounding needling, pricking and cupping method combined with bloodletting at Longyan （Extra） achieves the significant analgesic effect on herpes zoster.展开更多
文摘Sand production and high water content in oil wells are two major challenges that restrict high and stable production in loose sandstone reservoirs.In this paper,nano SiO_(2),coupling agent triethoxysilane,phenolic resin and n-octanol were used to synthesize the main agent SCA-2.Hexamethylenetetramine and vinyl carbonate were selected to prepare the curing agent YGA-1,which was then compounded with SCA-2 to develop a sand fixation and water plugging system.Firstly,single-factor experiments were conducted to determine the optimal concentrations of SCA-2 and YGA-1,subsequently,the system’s sand fixation and water blocking performance were evaluated.Finally,a pilot test was carried out in the mining site.Experimental results showed that the optimal formula composition of the system was 10%SCA-2+5%YGA-1.The gelation time of the system was 180 minutes and the viscosity after gelation could reach 108.4 mPa·s.When the dosage of the drug system was 0.6 PV,the sand production rate remained below 0.08%.Dual-tube parallel experiments showed that the sand fixation and water plugging system had a water flow channel plugging rate of 87.5%,while the oil flow channel plugging rate was only 11.3%,indicating minimal damage to the oil-bearing reservoir.The field test showed that after the measures taken in Well M of X oilfield,the sand free oil recovery period exceeded 360 days,the water content decreased by 5.0%and the cumulative oil production increased by 7092 m^(3).This study provides new ideas for efficient development of loose sandstone reservoirs.
基金supported by the National Natural Science Foundation of China(Grant Nos.42150204 and 2288101)supported by the China National Postdoctoral Program for Innovative Talents(BX20230045)the China Postdoctoral Science Foundation(2023M730279)。
文摘A nonlinear multi-scale interaction(NMI)model was proposed and developed by the first author for nearly 30 years to represent the evolution of atmospheric blocking.In this review paper,we first review the creation and development of the NMI model and then emphasize that the NMI model represents a new tool for identifying the basic physics of how climate change influences mid-to-high latitude weather extremes.The building of the NMI model took place over three main periods.In the 1990s,a nonlinear Schr?dinger(NLS)equation model was presented to describe atmospheric blocking as a wave packet;however,it could not depict the lifetime(10-20 days)of atmospheric blocking.In the 2000s,we proposed an NMI model of atmospheric blocking in a uniform basic flow by making a scale-separation assumption and deriving an eddyforced NLS equation.This model succeeded in describing the life cycle of atmospheric blocking.In the 2020s,the NMI model was extended to include the impact of a changing climate mainly by altering the basic zonal winds and the magnitude of the meridional background potential vorticity gradient(PVy).Model results show that when PVy is smaller,blocking has a weaker dispersion and a stronger nonlinearity,so blocking can be more persistent and have a larger zonal scale and weaker eastward movement,thus favoring stronger weather extremes.However,when PVy is much smaller and below a critical threshold under much stronger winter Arctic warming of global warming,atmospheric blocking becomes locally less persistent and shows a much stronger westward movement,which acts to inhibit local cold extremes.Such a case does not happen in summer under global warming because PVy fails to fall below the critical threshold.Thus,our theory indicates that global warming can render summer-blocking anticyclones and mid-to-high latitude heatwaves more persistent,intense,and widespread.
基金National Natural Science Foundation of China(52175237)。
文摘The key parameters that characterize the morphological quality of multi-layer and multi-pass metal laser deposited parts are the surface roughness and the error between the actual printing height and the theoretical model height.The Taguchi method was employed to establish the correlations between process parameter combinations and multi-objective characterization of metal deposition morphology(height error and roughness).Results show that using the signal-to-noise ratio and grey relational analysis,the optimal parameter combination for multi-layer and multi-pass deposition is determined as follows:laser power of 800 W,powder feeding rate of 0.3 r/min,step distance of 1.6 mm,and scanning speed of 20 mm/s.Subsequently,a Genetic Bayesian-back propagation(GB-BP)network is constructed to predict multi-objective responses.Compared with the traditional back propagation network,the GB-back propagation network improves the prediction accuracy of height error and surface roughness by 43.14%and 71.43%,respectively.This network can accurately predict the multi-objective characterization of morphological quality of multi-layer and multi-pass metal deposited parts.
基金supported by the National Natural Science Foundation of China under Grant No.41821004,the National Key Research and Development Program of China under contract No.2022YFE0140500the National Key R&D Program of China under contract No.2022YFA1004403+2 种基金the Laoshan Laboratory Science and Technology Innovation Project No.LSKJ202202104the National Nature Science Foundation of China No.42130406the Project of Doctoral Found of Qingdao University of Science and Technology under contract No.210010022746.
文摘Three extreme cold events occurred in eastern Asia in January 2016,January 2021,and December 2023.As important factors in atmospheric circulation anomalies,the Blocking High and East Asian Trough(BH-ET)structure played key roles during these three extreme cold wave events.Among these two dynamic patterns,the BH affected the development of the cold waves in two different ways:(1)before the cold waves in 2016 and 2023,the BH pushed the cold air southward,resulting in a slow and gradual cooling,with a cooling rate(CR)in eastern Asia of 1.34℃d^(-1)and 1.2℃d^(-1),respectively,and(2)in January 2021,the sudden collapse of BH caused the cold air to rapidly attack mid-latitude regions,with a CR of 1.87℃d^(-1).In terms of the spatial CR,the temperature drop in 2021 occurred 38.8%and 55%faster than those in 2016 and 2023,respectively.At the same time,the ET influences the wind direction of cold waves by modulating the pressure gradient.Before the cold waves occurred,the meridional wind field near the ET showed negative values,forming northwesterly or northeasterly winds,which continued to affect the southern part of East Asia.The meridional wind in January 2021 was stronger than those in 2016 and 2023,which is thought to be the reason for the strength of the 2021 cold wave.Finally,results from the temperature Empirical Orthogonal Function(EOF)analysis from 1980-2023 verify an obvious BH-ET structure in the three cold wave events,which suggests that this particular climatological state provides a climatic background for the occurrence of cold waves.
基金supported by the Nano&Material Technology Development Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science and ICT(RS-2024-00436563)supported by Brain Pool program funded by the Ministry of Science and ICT through the National Research Foundation of Korea(Grant No.RS-2023-00284361).
文摘Seawater is the most abundant source of molecular hydrogen.Utilizing the hydrogen reserves present in the seawater may inaugurate innovative strategies aimed at advancing sustainable energy and environmental preservation endeavors in the future.Recently,there has been a surge in study in the field addressing the production of hydrogen through the electrochemical seawater splitting.However,the performance and durability of the electrode have limitations due to the fact that there are a few challenges that need to be addressed in order to make the technology suitable for the industrial purpose.The active site blockage caused by chloride ions that are prevalent in seawater and chloride corrosion is the most significant issue;it has a negative impact on both the activity and the durability of the anode component.Addressing this particular issue is of upmost importance in the seawater splitting area.This review concentrates on the newly developed materials and techniques for inhibiting chloride ions by blocking the active sites,simultaneously preventing the chloride corrosion.It is anticipated that the concept will be advantageous for a large audience and will inspire researchers to study on this particular area of concern.
基金supported by Medical Science and Technology Research Project of Henan Province(Joint Construction Project)(No.LHGJ20200433)National Natural Science Foundation of China(No.52122308)。
文摘White light illumination is essential in daily life,however,the substantial amount of blue light it contains can damage human eyes.Therefore,it is important to block this high-energy blue light to protect visual health.In this study,yellow-emitting carbon dots(CDs)with a quantum yield exceeding 94%were synthesized using citric acid and urea.These CDs effectively absorb blue light.By incorporating them into polystyrene,multiple films termed CDs-based blue light blocking films(CBFs)were developed,each offering different levels of blue light absorption.These CBFs exhibited excellent transparency and efficient blue light filtering capabilities.This study highlights the potential of high quantum yield CDs,which specifically absorb blue light,as foundational materials for developing light-blocking solutions against highenergy short-wavelength light.
文摘In this paper,we present a necessary and sufficient condition for hyponormal block Toeplitz operators T on the vector-valued weighted Bergman space with symbolsΦ(z)=G^(*)(z)+F(z),where F(z)=∑^(N)_(i)=1 A_(i)z^(i)and G(z)=∑^(N)_(i)=1 A_(−i)z^(i),A_(i)ae culants.
基金partially supported by the National Key Research and Development Program of the Ministry of Science and Technology of China(2022YFE0114200)the National Natural Science Foundation of China(U20A6004).
文摘This paper investigates a distributed heterogeneous hybrid blocking flow-shop scheduling problem(DHHBFSP)designed to minimize the total tardiness and total energy consumption simultaneously,and proposes an improved proximal policy optimization(IPPO)method to make real-time decisions for the DHHBFSP.A multi-objective Markov decision process is modeled for the DHHBFSP,where the reward function is represented by a vector with dynamic weights instead of the common objectiverelated scalar value.A factory agent(FA)is formulated for each factory to select unscheduled jobs and is trained by the proposed IPPO to improve the decision quality.Multiple FAs work asynchronously to allocate jobs that arrive randomly at the shop.A two-stage training strategy is introduced in the IPPO,which learns from both single-and dual-policy data for better data utilization.The proposed IPPO is tested on randomly generated instances and compared with variants of the basic proximal policy optimization(PPO),dispatch rules,multi-objective metaheuristics,and multi-agent reinforcement learning methods.Extensive experimental results suggest that the proposed strategies offer significant improvements to the basic PPO,and the proposed IPPO outperforms the state-of-the-art scheduling methods in both convergence and solution quality.
文摘BACKGROUND A major cause of mortality in the coronavirus disease 2019(COVID-19)pandemic was acute respiratory distress syndrome(ARDS).Currently,moderate to severe ARDS induced by COVID-19(COVID ARDS)and other viral and non-viral etiologies are treated by traditional ARDS protocols that recommend 12-16 hours of prone position ventilation(PPV)with neuromuscular blocking agents(NMBA)and a trial of inhaled vasodilators(IVd)if oxygenation does not improve.However,debate on the efficacy of adjuncts to PPV and low tidal volume ventilation persists and evidence about the benefits of IVd/NMBA in COVID ARDS is sparse.In our multi-center retrospective review,we evaluated the impact of PPV,IVd,and NMBA on outcomes and lung mechanics in COVID ARDS patients with moderate to severe ARDS.AIM To evaluate the impact of PPV used alone or in combination with pulmonary IVd and/or NMBA in mechanically ventilated patients with moderate to severe ARDS during the COVID-19 pandemic.METHODS A retrospective study at two tertiary academic medical centers compared outcomes between COVID ARDS patients receiving PPV and patients in the supine position.PPV patients were divided based on concurrent use of ARDS adjunct therapies resulting in four subgroups:(1)PPV alone;(2)PPV and IVd;(3)PPV and NMBA;and(4)PPV,IVd,and NMBA.Primary outcomes were hospital and intensive care unit(ICU)length of stay(LOS),mortality,and venovenous extracorporeal membrane oxygenation(VV-ECMO)status.Secondary outcomes included changes in lung mechanics at 24-hour intervals for 7 days.RESULTS Total 114 patients were included in this study.Baseline respiratory parameters and Sequential Organ Failure Assessment scores were significantly worse in the PPV group.ICU LOS and LOS were significantly longer for patients who were proned,but no mortality benefit or difference in VV-ECMO status was found.Among the subgroups,no difference in primary outcomes were found.In the secondary analysis,PPV was associated with a significant improvement in arterial oxygen partial pressure(PaO_(2))/fractional inspired oxygen(FiO_(2))(P/F)ratio from day 1 to day 4(P<0.05)and higher driving pressures day 5 to day 7(P<0.05).The combination of PPV and IVd together resulted in improvements in P/F ratio from day 1 to day 7 and plateau pressure on day 4 and day 6(P<0.05).PPV with NMBA was not associated with improvements in any of the secondary outcomes.The use of all three rescue therapies together resulted in improvements in lung compliance on day 2(P<0.05)but no other improvements.CONCLUSION In mechanically ventilated patients diagnosed with moderate to severe COVID ARDS,PPV and PPV with the addition of IVd produced a significant and sustained increase in P/F ratio.The combination of PPV,IVd and NMBA improved compliance however this did not reach significance.Mortality and LOS did not improve with adjunct therapies.Further research is warranted to determine the efficacy of these therapies alone and in combination in the treatment of COVID ARDS.
基金Military Healthcare Special Scientific Research Project(25BJZ31, awarded to SHI XM)。
文摘When patients initially present with atrial fibrillation along with an enlarged heart and heart failure, followed by atrioventricular block, it's essential to consider genetic factors.^([1])Genetic testing can offer crucial diagnostic evidence, aiding in prognosis assessment and the adoption of appropriate treatment strategies.
基金support from National Science Foundation of China(22438005)the Natural Science Foundation of Jiangsu Province(BE2022056-3)is gratefully acknowledged.
文摘Nanoporous polymers are extensively coated on various substrates to deliver optical,permselective,or other functions.However,it remains desired to fast produce uniform nanoporous polymer coatings on substrates with complex surfaces.Herein,by manipulating the interactions between block copolymers and selective solvents,we prepare repairable nanoporous polymers on arbitrary substrates.This is realized by an extremely simple sequential coating process:sequential coating of block copolymers and their swelling agents on substrate surfaces.The swelling agents are comprised of two solvents that swell the constituent blocks of the copolymers to different degrees,rapidly producing polymer coatings with uniform,interconnected,sub-50 nm pores.This sequential coating process is able to conformally build nanoporous polymers on nonplanar substrates with large lateral sizes and complex surface features,and also to in situ repair defects arising during usages.We further demonstrate that the nanoporous coatings show excellent antireflective and membrane separation performances.This sequential coating process is dictated by polymer–solvent interactions,and is expected to find applications in diverse fields for its simplicity,adaptability,and the capability to produce well-defined nanoporosities.
基金supported by the National Natural Science Foundation of China (Nos.22208218,22078196,and 22278268)the Natural Science Foundation of Shanghai (No.22ZR1460400)Collaborative Innovation Center of Fragrance Flavour and Cosmetics,and Collaborative Innovation Project of Shanghai Institute of Technology (No.XTCX2023-07)。
文摘The diagnostic efficacy of contemporary bioimaging technologies remains constrained by inherent limitations of conventional imaging agents,including suboptimal sensitivity,off-target biodistribution,and inherent cytotoxicity.These limitations have catalyzed the development of intelligent stimuli-responsive block copolymers-based bioimaging agents,which was engineered to dynamically respond to endogenous biochemical cues(e.g.,p H gradients,redox potential,enzyme activity,hypoxia environment) or exogenous physical triggers(e.g.,photoirradiation,thermal gradients,ultrasound(US)/magnetic stimuli).Through spatiotemporally controlled structural transformations,stimuli-responsive block copolymers enable precise contrast targeting,activatable signal amplification,and theranostic integration,thereby substantially enhancing signal-to-noise ratios of bioimaging and diagnostic specificity.Hence,this mini-review systematically examines molecular engineering principles for designing p H-,redox-,enzyme-,light-,thermo-,and US/magnetic-responsive polymers,with emphasis on structure-property relationships governing imaging performance modulation.Furthermore,we critically analyze emerging strategies for optical imaging,US synergies,and magnetic resonance imaging(MRI).Multimodal bioimaging has also been elaborated,which could overcome the inherent trade-offs between resolution,penetration depth,and functional specificity in single-modal approaches.By elucidating mechanistic insights and translational challenges,this mini-review aims to establish a design framework of stimuli-responsive block copolymersbased for high fidelity bioimaging agents and accelerate their clinical translation in precise diagnosis and therapy.
基金financially supported by National Key R&D Program Young Scientists Project(No.2023YFC3903100)the National Natural Science Foundation of China(No.22322503)analytical and testing assistance from the Analysis and Testing Center of HUST。
文摘Switchable polymerization is emerging as a powerful tool to construct block copolymers directly from mixtures of monomers.However,current achievements typically iterate between two polymerization cycles to afford products with fixed sequences and compositions.Herein,we report the triethylborane/1,8-diazabicyclo[5.4.0]undec-7-ene(Et_3B/DBU)pair-mediated four-component switchable polymerization of propylene oxide(PO),CO_(2),phthalic anhydride(PA),and racemic lactide(rac-LA),which enables the on-demand synthesis of four different block copolymers,i.e.,poly(propylene phthalate)-b-polylactide(PPE-b-PLA),PPE-b-PLA-b-poly(propylene carbonate)(PPC),PPE-b-PPC-b-PLA,and PPE-b-PPCb-poly(propylene oxide)(PPO),through rationally modulating the Lewis pair(LP)ratio.Core to this protocol is that increasing the loading of Et_(3)B accelerates the ring-opening of PO while impeding the reactivity of rac-LA,thus allowing for fine-tuning of the thermodynamic and kinetic of the switchable polymerization.Therefore,the four polymerization cycles involving PO/PA ring-opening copolymerization(ROCOP),PO/CO_(2) ROCOP,rac-LA ring-opening polymerization(ROP),and PO ROP can be connected and discriminated in precisely programmed manners.
基金support from Research Council of Norway via STIPINST PhD grant(Grant No.323307),Bever Control AS,and Bane NOR.
文摘This paper presents a novel artificial intelligence(AI)-assisted two-stage method for optimising rock slope stability by integrating advanced 3D modelling with rock support design,aiming at minimising risks,material usage,and costs.In the first stage,an extended key block analysis identifies key blocks and key block groups,accounting for progressive failure and force interactions.The second stage uses AI algorithms to optimise rockbolting design,balancing stability,cost,and material use.The most efficient algorithms include the multi-objective tree-structured Parzen estimator(MOTPE)and non-dominated sorting genetic algorithms(NSGA-II and NSGA-III).Applied to the Larvik rock slope,the optimised solution uses 18 pre-tensioned cablebolts,providing 13.2 MN of active force and achieving a factor of safety of 1.31 while reducing the average anchorage length by approximately 16%compared to traditional design.The AI-assisted approach also reduces computation time by over 90%compared to Quasi-Monte Carlo(QMC)methods,demonstrating its efficiency for small-scale civil engineering projects and large-scale mining operations.The developed tool is practical,compatible with Building Information Modelling(BIM),and ready for engineering implementation,supporting sustainable and cost-effective rock slope stabilisation.While the method is largely automated,professional judgement remains crucial for verifying ground conditions and selecting the final solution.Future work will focus on integrating data uncertainties,addressing complex block deformation mechanisms,refining optimisation objectives,and improving the performance of multi-objective optimisation for slope rockboling applications to further enhance the method's versatility.
基金supported by the National Natural Science Foundation of China(No.52274346).
文摘Waste graphitization cathode carbon blocks are a type of hazardous solid waste generated during the aluminum electrolysis process,and their proper disposal is a key step in the resource utilization of discarded graphite.This study utilizes the porous“defect advantage”of a cathode carbon block matrix to prepare silicon-doped and asphalt-coated detoxified and purified waste graphitization cathode carbon blocks for use as high-performance silicon/carbon composite anode materials.The results show that the uniformly silicondoped silicon/carbon composite material features a unique amorphous carbon-encapsulated“locked silicon”structure,which effectively addresses issues such as cathode volume expansion,excessive growth of the solid electrolyte interphase(SEI)film,and poor electrical contact between active materials.Consequently,electrochemical performance is enhanced.After assembly in a half-cell,the PSCC/10%Si@C(purified waste graphitization cathode carbon/10%Si@C)material exhibits optimal electrochemical stability,with an initial charging specific capacity of 514.5 mAh/g at 0.1 C(1 C=170 mA/g)and a capacity retention rate of 95.1%after 100 cycles.At a charge rate of 2.0 C,a specific capacity of 216.9 mAh/g is achieved.This technology provides a new pathway for the economical and high-value utilization of waste cathode carbon blocks and the development of low-cost,high-performance anode materials.
基金financially supported by the Russian Science Foundation(No.23-13-00205)。
文摘Star-shaped six-arm polymers with hexaaza[2_(6)]orthoparacyclophane core and arms of block copolymers of poly-2-ethyl-5,6-dihydrooxazine with poly-2-isopropyl-5,6-dihydrooxazine were synthesized successfully using cationic ring-opening polymerization.The ratio of blocks,the order of their attachment to the core,and arm length were varied.Conformation of synthesized stars was determined by methods of molecular hydrodynamics and optics.It has been shown that star-shaped molecules were characterized by high intramolecular density,and the arm folding increased with their lengthening.The influence of the structure of block copolymers and their molar mass on the critical micelle concentration has been established.Complexes of synthesized star-shaped block copolymers with curcumin were obtained and the efficient binding of curcumin to polymer molecules was demonstrated.The behavior of the aqueous solutions of the prepared polymer stars and their complexes with curcumin was investigated by light scattering and turbidimetry methods.The influence of the structure and molar mass of star polymers on their thermoresponsiveness and the phase separation temperatures in aqueous solutions was analyzed.A slight increase in the phase separation temperature was found on passage from polymer solutions to solutions of polymer complexes with hydrophobic curcumin.
文摘Some novel techniques of computational fluid dynamics are used to establish a mathematical model for the open diversion channel with two embankments in river blocking.The technique of boundary fitted coordinate system is used to overcome the difficulties resulting from the complicated shapes of natural river boundaries;the method of alternating direction implicit finite difference scheme is used to solve the partial differential equations in the transformed plane;and the technique of moving boundary is used to deal with the river bed exposed to water surface.This model has been used to predict the flow characteristics in the blocking of the Yangtz river in the Three Gorge Project (TGP).Comparison between the computed and experimental data shows a satisfactory agreement.
文摘Objective To observe the analgesic effect on herpes zoster treated by the comprehensive therapy of blocking, surrounding needling, pricking and cupping combined with bloodletting at Longyan （龙眼, Extra） acupoint. Methods According to the random mumber table, 104 cases of herpes zoster were randomized into an observation group and a control group, 52 cases in each one. In the observation group, the blocking method was used at the starting site and the ending site of herpetic zone, the surrounding needling method was applied toward the center of the painful zone, with horizontal needling technique; and the local pricking and cupping methods as well as the bloodletting at Longyan （Extra） acupoint were adopted. In the control group, Jiáj （夹脊 EX-B 2） at the corresponding affected nerve segments and the local Ashi points were selected and stimulated with electroacupuncture. The visual analogue scale （VAS） was adopted to determine the analgesic effect 20 min, 1, 6, 12, 24 and 48 h after treatment separately in each group. Results The onset time of analgesic effect in the observation group was shorter than that in the control group and the efficacy time of duration was longer than that in the control group （all P0.05）. The analgesic effect and the result of comprehensive efficacy assessment were superior to those of the control group （both P0.05）. Conclusion The comprehensive therapy of blocking, surrounding needling, pricking and cupping method combined with bloodletting at Longyan （Extra） achieves the significant analgesic effect on herpes zoster.
