The high mortality rates of colon and rectal tumors have put forward an urgent need for rapid, sensitive, and accurate diagnosis. The polarization imaging technology, with the advantages of noninvasiveness, noncontact...The high mortality rates of colon and rectal tumors have put forward an urgent need for rapid, sensitive, and accurate diagnosis. The polarization imaging technology, with the advantages of noninvasiveness, noncontact, quantification, rapidity, and high sensitivity, is expected to be used for auxiliary diagnosis of colorectal cancer. Herein, the differences in colorectal tissues of four pathological types were studied using this powerful technology. Polarized light imaging combined with the Mueller matrix decomposition (MMPD) method was applied to extract structural features that may be related to colorectal tumors. It demonstrated that parameters δ and θ could reflect the structural differences of colorectal tumors. Preliminary simulated experiment results revealed that the parameter δ was related to the fiber density, and the parameter θ was related to the fiber angle. Then Tamura image texture analysis was used to quantitatively describe tissues of different pathological types, and the results showed that the coarseness, contrast, directionality, and roughness of the four groups were statistically different. Texture analysis based on the quantitative data of the four dimensions could be applied for the identification of benign and malignant colorectal tumors.展开更多
Cardiovascular damage caused by cancer treatment has become an important cause of death for tumor survivors.With the recognition of cardiovascular diseases and cancer therapy-related cardiovascular toxicity(CTR-CVT)in...Cardiovascular damage caused by cancer treatment has become an important cause of death for tumor survivors.With the recognition of cardiovascular diseases and cancer therapy-related cardiovascular toxicity(CTR-CVT)in tumor patients,noninvasive imaging technologies play pivotal roles in the risk stratification,early diagnosis,monitoring and follow-up for CTR-CVT.In recent years,the field of cardio-oncology has witnessed continual updates in diagnostic and therapeutic strategies,with several pertinent guidelines and expert consensus documents issued in China and abroad.However,there remains a conspicuous absence of systematic guidance documents on the application of imaging techniques in the clinical practice of cardio-oncology.Therefore,the Chinese Anti-Cancer Association Society of Integrative Cardio-oncology,the Ultrasound Branch of the Chinese Medical Association,and the Chinese Society of Echocardiography convened experts to formulate the"Chinese guideline for the clinical application of noninvasive imaging technology in accessing cancer therapy-related cardiovascular toxicity".Building upon the systematic evaluation of guidelines and the latest evidence-based medical research in the field of cardio-oncology domestically and abroad,and in conjunction with data derived from evidence-based medical research in China,this guideline proposes noninvasive imaging examination methods and monitoring strategies for CTR-CVT,aiming to further standardize and guide the clinical practice of multidisciplinary physicians specializing in cardio-oncology in China.展开更多
Traditional laparoscopic liver cancer resection faces challenges,such as difficultiesin tumor localization and accurate marking of liver segments,as well as theinability to provide real-time intraoperative navigation....Traditional laparoscopic liver cancer resection faces challenges,such as difficultiesin tumor localization and accurate marking of liver segments,as well as theinability to provide real-time intraoperative navigation.This approach falls shortof meeting the demands for precise and anatomical liver resection.The introductionof fluorescence imaging technology,particularly indocyanine green,hasdemonstrated significant advantages in visualizing bile ducts,tumor localization,segment staining,microscopic lesion display,margin examination,and lymphnode visualization.This technology addresses the inherent limitations oftraditional laparoscopy,which lacks direct tactile feedback,and is increasinglybecoming the standard in laparoscopic procedures.Guided by fluorescenceimaging technology,laparoscopic liver cancer resection is poised to become thepredominant technique for liver tumor removal,enhancing the accuracy,safetyand efficiency of the procedure.展开更多
Skin imaging technologies such as dermoscopy, high-frequency ultrasound, reflective confocal microscopy and optical coherence tomography are developing rapidly in clinical application. Skin imaging technology can impr...Skin imaging technologies such as dermoscopy, high-frequency ultrasound, reflective confocal microscopy and optical coherence tomography are developing rapidly in clinical application. Skin imaging technology can improve clinical diagnosis rate, and its non-invasiveness and repeatability make it occupy an irreplaceable position in clinical diagnosis. With the “booming development” of medical technology, skin imaging technology can improve clinical diagnosis rate. Researchers have made significant advances in assisting clinical diagnosis, prediction, and treatment of disease. This article reviews the application and progress of skin imaging in the diagnosis of psoriasis.展开更多
Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biot...Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.展开更多
BACKGROUND Duodenal web is a rare congenital malformation,exceedingly uncommon in adults,and often misdiagnosed due to the subtle imaging features.CASE SUMMARY By analyzing the clinical diagnosis process and various i...BACKGROUND Duodenal web is a rare congenital malformation,exceedingly uncommon in adults,and often misdiagnosed due to the subtle imaging features.CASE SUMMARY By analyzing the clinical diagnosis process and various imaging findings of a patient from our institution,this case report emphasizes the necessity of upper gastrointestinal series in diagnosing duodenal webs,outlines its typical radiographic features,and provides a literature review on the etiology,clinical presentation,and management of this condition.CONCLUSION This case report emphasizes the necessity of upper gastrointestinal series in diagnosing duodenal webs.展开更多
With the reform and opening up entering a new era,China’s modern civilization and technology are“rolling forward”.In the medical field,innovative changes in radiology imaging technology have presented unprecedented...With the reform and opening up entering a new era,China’s modern civilization and technology are“rolling forward”.In the medical field,innovative changes in radiology imaging technology have presented unprecedented value opportunities in tumor diagnosis.Therefore,this article explores the classification of radiological imaging techniques,specifically including X-ray imaging,Computed Tomography(CT),Magnetic Resonance Imaging(MRI),Positron Emission Tomography(PET),and ultrasound imaging.Furthermore,it analyzes the practical application of these key technologies in tumor diagnosis and propose new ideas.In the end,the advantages and characteristics of radiology imaging technology are evaluated,and two limitations are also pointed out,which deserves profound reflection.展开更多
Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised m...Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised models such as 3D U-Net perform well in this domain,but their accuracy significantly improves with appropriate preprocessing.This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model(GGMM)to T1 contrastenhanced MRI scans from the BraTS 2020 dataset.The Expectation-Maximization(EM)algorithm is employed to estimate parameters for four tissue classes,generating a new pre-segmented channel that enhances the training and performance of the 3DU-Net model.The proposed GGMM+3D U-Net framework achieved a Dice coefficient of 0.88 for whole tumor segmentation,outperforming both the standard multiscale 3D U-Net(0.84)and MMU-Net(0.85).It also delivered higher Intersection over Union(IoU)scores compared to models trained without preprocessing or with simpler GMM-based segmentation.These results,supported by qualitative visualizations,suggest that GGMM-based preprocessing should be integrated into brain tumor segmentation pipelines to optimize performance.展开更多
Background:Quantum-enhanced medical imaging algorithms–quantum entanglement reconstruction,quantum noise suppression,and quantum beamforming–propose possible remedies for significant constraints in traditional diagn...Background:Quantum-enhanced medical imaging algorithms–quantum entanglement reconstruction,quantum noise suppression,and quantum beamforming–propose possible remedies for significant constraints in traditional diagnostic imaging,such as resolution,radiation efficiency,and real-time processing.Methods:This work used a mixed-methods strategy,including controlled phantom experiments,retrospective multi-center clinical data analysis,and quantum-classical hybrid processing to assess enhancements in resolution,dosage efficiency,and diagnostic confidence.Statistical validation included analysis of variance(ANOVA)and receiver-operating characteristic curve analysis,juxtaposing quantum-enhanced methodologies with conventional and deep learning approaches.Results:Quantum entanglement reconstruction enhanced magnetic resonance imaging spatial resolution by 33.2%(P<0.01),quantum noise suppression facilitated computed tomography scans with a 60%reduction in radiation,and quantum beamforming improved ultrasound contrast by 27%while preserving real-time processing(<2 ms delay).Inter-reader variability(12%in Diagnostic Confidence Scores)showed that systematic training is needed,even if the performance was better.The research presented(1)a reusable clinical quantum imaging framework,(2)enhanced hardware processes(field-programmable gate array/graphics processing unit acceleration),and(3)cost-benefit analyses demonstrating a 22-month return on investment breakeven point.Conclusion:Quantum-enhanced imaging has a lot of promise for use in medicine,especially in neurology and cancer.Future research should focus on multi-modal integration(e.g.,positron emission tomography–magnetic resonance imaging),cloud-based quantum simulations for enhanced accessibility,and extensive trials to confirm long-term diagnostic accuracy.This breakthrough gives healthcare systems a technology roadmap and a reason to spend money on quantum-enhanced diagnostics.展开更多
Airborne hyperspectral imaging spectrometers have been used for Earth observation over the past four decades.Despite the high sensitivity of push-broom hyperspectral imagers,they experience limited swath and wavelengt...Airborne hyperspectral imaging spectrometers have been used for Earth observation over the past four decades.Despite the high sensitivity of push-broom hyperspectral imagers,they experience limited swath and wavelength coverage.In this study,we report the development of a push-broom airborne multimodular imaging spectrometer(AMMIS)that spans ultraviolet(UV),visible near-infrared(VNIR),shortwave infrared(SWIR),and thermal infrared(TIR)wavelengths.As an integral part of China's HighResolution Earth Observation Program,AMMIS is intended for civilian applications and for validating key technologies for future spaceborne hyperspectral payloads.It has been mounted on aircraft platforms such as Y-5,Y-12,and XZ-60.Since 2016,AMMIS has been used to perform more than 30 flight campaigns and gather more than 200 TB of hyperspectral data.This study describes the system design,calibration techniques,performance tests,flight campaigns,and applications of the AMMIS.The system integrates UV,VNIR,SWIR,and TIR modules,which can be operated in combination or individually based on the application requirements.Each module includes three spectrometers,utilizing field-of-view(FOV)stitching technology to achieve a 40°FOV,thereby enhancing operational efficiency.We designed advanced optical systems for all modules,particularly for the TIR module,and employed cryogenic optical technology to maintain optical system stability at 100 K.Both laboratory and in-flight calibrations were conducted to improve preprocessing accuracy and produce high-quality hyperspectral data.The AMMIS features more than 1400 spectral bands,with spectral sampling intervals of 0.1 nm for UV,2.4 nm for VNIR,3 nm for SWIR,and 32 nm for TIR.In addition,the instantaneous fields of view(IFoVs)for the four modules were 0.5,0.25,0.5,and 1 mrad,respectively,with the VNIR module achieving an IFoV of 0.125 mrad in the high-spatial-resolution mode.This study reports on land-cover surveys,pollution gas detection,mineral exploration,coastal water detection,and plant investigations conducted using AMMIS,highlighting its excellent performance.Furthermore,we present three hyperspectral datasets with diverse scene distributions and categories suitable for developing artificial intelligence algorithms.This study paves the way for next-generation airborne and spaceborne hyperspectral payloads and serves as a valuable reference for hyperspectral sensor designers and data users.展开更多
1.Introduction Infrared Imaging Missiles(IRIMs)are advanced weapons utilizing infrared technology for target detection and tracking.Their sensors capture thermal signatures and convert them into electronic images,enab...1.Introduction Infrared Imaging Missiles(IRIMs)are advanced weapons utilizing infrared technology for target detection and tracking.Their sensors capture thermal signatures and convert them into electronic images,enabling precise target identification and tracking.To a certain extent,the all-weather adaptability of IRIMs enables their effective operation across diverse environmental conditions,providing high targeting accuracy and cost efficiency.展开更多
BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)is a pivotal intervention for managing esophagogastric variceal bleeding in patients with chronic hepatic schistosomiasis.AIM To evaluate the efficacy of d...BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)is a pivotal intervention for managing esophagogastric variceal bleeding in patients with chronic hepatic schistosomiasis.AIM To evaluate the efficacy of digital subtraction angiography image overlay tech-nology(DIT)in guiding the TIPS procedure.METHODS We conducted a retrospective analysis of patients who underwent TIPS at our hospital,comparing outcomes between an ultrasound-guided group and a DIT-guided group.Our analysis focused on the duration of the portosystemic shunt puncture,the number of punctures needed,the total surgical time,and various clinical indicators related to the surgery.RESULTS The study included 52 patients with esophagogastric varices due to chronic hepatic schistosomiasis.Results demonstrated that the DIT-guided group expe-rienced significantly shorter puncture times(P<0.001)and surgical durations(P=0.022)compared to the ultrasound-guided group.Additionally,postoperative assessments showed significant reductions in aspartate aminotransferase,B-type natriuretic peptide,and portal vein pressure in both groups.Notably,the DIT-guided group also showed significant reductions in total bilirubin(P=0.001)and alanine aminotransferase(P=0.023).CONCLUSION The use of DIT for guiding TIPS procedures highlights its potential to enhance procedural efficiency and reduce surgical times in the treatment of esophagogastric variceal bleeding in patients with chronic hepatic schistoso-miasis.展开更多
Radiation‐induced heart disease(RIHD)is a heterogeneous,delayed,and potentially fatal adverse reaction to radiation that can damage all structures of the heart,including the pericardium,myocardium,coronary arteries,v...Radiation‐induced heart disease(RIHD)is a heterogeneous,delayed,and potentially fatal adverse reaction to radiation that can damage all structures of the heart,including the pericardium,myocardium,coronary arteries,valves,and conduction system,leading to a series of diseases.Acute and chronic disease processes play a role in the development of RIHD,the onset times of which range from months to decades.However,the clinical manifestations of RIHD are usually insidious,overlap with several other diseases,and lack specificity.Cardiovascular imaging is essential for early diagnosis,follow‐up,and outcome assessment in patients with RIHD.This review first describes the pathogenesis and clinical manifestations of RIHD before providing an overview of the practical approaches and research advances in multimodal cardiovascular imaging in patients with RIHD,including echocardiography,cardiac magnetic resonance(CMR)and nuclear medicine,and cardiac computed tomography(CT).Then,the value of new cardiac imaging assessments for the early diagnosis of RIHD is described,particularly with relation to speckle‐tracking echocardiography,extracellular volume fraction assessment as a quantitative CMR technique,CMR myocardial strain assessment,positron emission tomography‐CT myocardial perfusion imaging,CT‐ECV,and CT strain assessment,amongst others.In addition,the advantages and disadvantages of each screening technique are compared with the aim of better guiding the follow‐up and diagnosis of subclinical RIHD and preventing cardiovascular events.展开更多
Acute pancreatitis(AP)is a potentially life-threatening inflammatory disease of the pancreas,with clinical management determined by the severity of the disease.Diagnosis,severity prediction,and prognosis assessment of...Acute pancreatitis(AP)is a potentially life-threatening inflammatory disease of the pancreas,with clinical management determined by the severity of the disease.Diagnosis,severity prediction,and prognosis assessment of AP typically involve the use of imaging technologies,such as computed tomography,magnetic resonance imaging,and ultrasound,and scoring systems,including Ranson,Acute Physiology and Chronic Health Evaluation II,and Bedside Index for Severity in AP scores.Computed tomography is considered the gold standard imaging modality for AP due to its high sensitivity and specificity,while magnetic resonance imaging and ultrasound can provide additional information on biliary obstruction and vascular complications.Scoring systems utilize clinical and laboratory parameters to classify AP patients into mild,moderate,or severe categories,guiding treatment decisions,such as intensive care unit admission,early enteral feeding,and antibiotic use.Despite the central role of imaging technologies and scoring systems in AP management,these methods have limitations in terms of accuracy,reproducibility,practicality and economics.Recent advancements of artificial intelligence(AI)provide new opportunities to enhance their performance by analyzing vast amounts of clinical and imaging data.AI algorithms can analyze large amounts of clinical and imaging data,identify scoring system patterns,and predict the clinical course of disease.AI-based models have shown promising results in predicting the severity and mortality of AP,but further validation and standardization are required before widespread clinical application.In addition,understanding the correlation between these three technologies will aid in developing new methods that can accurately,sensitively,and specifically be used in the diagnosis,severity prediction,and prognosis assessment of AP through complementary advantages.展开更多
By utilizing wave velocity imaging technology,the uniaxial multi-stage loading test was conducted on siltstone to attain wave velocity imagings during rock fracture.Based on the time series parameters of acoustic emis...By utilizing wave velocity imaging technology,the uniaxial multi-stage loading test was conducted on siltstone to attain wave velocity imagings during rock fracture.Based on the time series parameters of acoustic emissions(AE),joint response characteristics of the velocity field and AE during rock fracture were analyzed.Moreover,the localization effect of damage during rock fracture was explored by applying wave velocity imagings.The experimental result showed that the wave velocity imagings enable three-dimensional(3-D)visualization of the extent and spatial position of damage to the rock.A damaged zone has a low wave velocity and a zone where the low wave velocity is concentrated tends to correspond to a severely damaged zone.AE parameters and wave velocity imagings depict the changes in activity of cracks during rock fracture from temporal and spatial perspectives,respectively:the activity of cracks is strengthened,and the rate of AE events increases during rock fracture;correspondingly,the low-velocity zones are gradually aggregated and their area gradually increases.From the wave velocity imagings,the damaged zones in rock were divided into an initially damaged zone,a progressively damaged zone,and a fractured zone.During rock fracture,the progressively damaged zone and the fractured zone both develop around the initially damaged zone,showing a typical localization effect of the damage.By capturing the spatial development trends of the progressively damaged zone and fractured zone in wave velocity imagings,the development of microfractures can be predicted,exerting practical significance for determining the position of the main fracture.展开更多
Three-dimensional(3D)printing technology is increasingly used in experimental research of geotechnical engineering.Compared to other materials,3D layer-by-layer printing specimens are extremely similar to the inherent...Three-dimensional(3D)printing technology is increasingly used in experimental research of geotechnical engineering.Compared to other materials,3D layer-by-layer printing specimens are extremely similar to the inherent properties of natural layered rock masses.In this paper,soft-hard interbedded rock masses with different dip angles were prepared based on 3D printing(3DP)sand core technology.Uniaxial compression creep tests were conducted to investigate its anisotropic creep behavior based on digital imaging correlation(DIC)technology.The results show that the anisotropic creep behavior of the 3DP soft-hard interbedded rock mass is mainly affected by the dip angles of the weak interlayer when the stress is at low levels.As the stress level increases,the effect of creep stress on its creep anisotropy increases significantly,and the dip angle is no longer the main factor.The minimum value of the long-term strength and creep failure strength always appears in the weak interlayer within 30°–60°,which explains why the failure of the layered rock mass is controlled by the weak interlayer and generally emerges at 45°.The tests results are verified by comparing with theoretical and other published studies.The feasibility of the 3DP soft-hard interbedded rock mass provides broad prospects and application values for 3DP technology in future experimental research.展开更多
Aiming at the problem that the lattice feature exceeds the view field of the scanning electron microscope(SEM)measuring system,a new lattice measuring method is proposed based on integral imaging technology.When the s...Aiming at the problem that the lattice feature exceeds the view field of the scanning electron microscope(SEM)measuring system,a new lattice measuring method is proposed based on integral imaging technology.When the system works,the SEM measuring system is equivalent to an integral image acquisition system.Firstly,a lattice measuring method is researched based on integral imaging theory.Secondly,the system parameters are calibrated by the VLSI lattice standard.Finally,the value of the lattice standard to be tested is determined based on the calibration parameters and the lattice measuring algorithm.The experimental results show that,compared with the traditional electron microscope measurement method,the relative error of the measured value of the algorithm is maintained within 0.2%,with the same level of measurement accuracy,but it expands the field of view of the electron microscope measurement system,which is suitable for the measurement of samples under high magnification.展开更多
Photodissociation dynamics of dichlorodifluoromethane (CF2Cl2) around 235 nm has been studied using the time-sliced velocity map imaging technology in combination with the resonance enhanced multi-photon ionization te...Photodissociation dynamics of dichlorodifluoromethane (CF2Cl2) around 235 nm has been studied using the time-sliced velocity map imaging technology in combination with the resonance enhanced multi-photon ionization technology. By measuring the raw images of chlorine atoms which are formed via one-photon dissociation of CF2Cl2, the speed and angular distributions can be directly obtained. The speed distribution of excited-state chlorine atoms consists of high translation energy (ET) and low ET components, which are related to direct dissociation on 3Q0 state and predissociation on the ground state induced by internal conversion, respectively. The speed distribution of ground-state chlorine atoms also consists of high ET and low ET components which are related to predissociation between 3Q0 and 1Q1 states and predissociation on the ground state induced by internal conversion, respectively. Radical dissociation channel is confirmed, nevertheless, secondary dissociation and three-body dissociation channels are excluded.展开更多
To solve the problem that the production of Mahu conglomerate reservoir is not up to expectation after the multi-cluster plus temporary plugging fracturing technology is applied in horizontal wells, stages 2–6 in the...To solve the problem that the production of Mahu conglomerate reservoir is not up to expectation after the multi-cluster plus temporary plugging fracturing technology is applied in horizontal wells, stages 2–6 in the test well MaHW6285 are selected to carry out erosion tests with different pumping parameters. The downhole video imaging technology is used to monitor the degree of perforations erosion, and then the fracture initiation and proppant distribution of each cluster are analyzed. The results showed that proppant entered 76.7% of the perforations. The proppant was mainly distributed in a few perforation clusters, and the amount of proppant entered in most of the clusters was limited. The proppant distribution in Stage 4 was relatively uniform, and the fracture initiation of each cluster in the stage is more uniform. The proppant distribution in stages 2, 3, 5, and 6 was significantly uneven, and the uniform degree of fracture initiation in each cluster is low. More than 70% of the proppant dose in the stage entered clusters near the heel end, so the addition of diverters did not promote the uniform initiation of hydraulic fractures. There was a positive correlation between the amount of proppant added and the degree of perforations erosion, and the degree of perforations erosion ranged from 15% to 352%, with an average value of 74.5%, which was far higher than the statistical results of shale reservoir tests in North America. The use of 180° phase perforation(horizontal direction) can reduce the “Phase Bias” of perforations erosion, promote uniform perforations erosion and fluid inflow. The research results provide the basis for optimizing the pumping procedure, reducing the perforation erosion and improving the success rate of diversion.展开更多
The Staring Area Imaging Technology(SAIT) satellite continuously "images" the target over a certain time range, and can realize continuous imaging and multi-angle imaging of the area of interest. It has the ...The Staring Area Imaging Technology(SAIT) satellite continuously "images" the target over a certain time range, and can realize continuous imaging and multi-angle imaging of the area of interest. It has the characteristics of flexible imaging parameter setting and fast image preprocessing speed, enabling dynamic target detection and tracking, super-resolution, surface 3 D model construction, night-time imaging and many other application tasks. Based on the technical characteristics of the SAIT satellite, this paper analyzes the challenges in satellite development and data processing, focuses on the quasi-realtime application of SAIT satellite data, and looks at the development trend of the SAIT satellite.展开更多
文摘The high mortality rates of colon and rectal tumors have put forward an urgent need for rapid, sensitive, and accurate diagnosis. The polarization imaging technology, with the advantages of noninvasiveness, noncontact, quantification, rapidity, and high sensitivity, is expected to be used for auxiliary diagnosis of colorectal cancer. Herein, the differences in colorectal tissues of four pathological types were studied using this powerful technology. Polarized light imaging combined with the Mueller matrix decomposition (MMPD) method was applied to extract structural features that may be related to colorectal tumors. It demonstrated that parameters δ and θ could reflect the structural differences of colorectal tumors. Preliminary simulated experiment results revealed that the parameter δ was related to the fiber density, and the parameter θ was related to the fiber angle. Then Tamura image texture analysis was used to quantitatively describe tissues of different pathological types, and the results showed that the coarseness, contrast, directionality, and roughness of the four groups were statistically different. Texture analysis based on the quantitative data of the four dimensions could be applied for the identification of benign and malignant colorectal tumors.
基金National Key Research and Development Program of China(2022YFC 3602400)Shanghai Municipal Health Commission“Top Priority Research Center”(2023-ZZ02021)+2 种基金Shanghai Public Health Key Discipline Construction Project(GWVI-11.1-26)Shanghai Academic/Technology Research Leader(21XD1432100)Key Research and Development Program of Shandong Province(2021SFGC0503)。
文摘Cardiovascular damage caused by cancer treatment has become an important cause of death for tumor survivors.With the recognition of cardiovascular diseases and cancer therapy-related cardiovascular toxicity(CTR-CVT)in tumor patients,noninvasive imaging technologies play pivotal roles in the risk stratification,early diagnosis,monitoring and follow-up for CTR-CVT.In recent years,the field of cardio-oncology has witnessed continual updates in diagnostic and therapeutic strategies,with several pertinent guidelines and expert consensus documents issued in China and abroad.However,there remains a conspicuous absence of systematic guidance documents on the application of imaging techniques in the clinical practice of cardio-oncology.Therefore,the Chinese Anti-Cancer Association Society of Integrative Cardio-oncology,the Ultrasound Branch of the Chinese Medical Association,and the Chinese Society of Echocardiography convened experts to formulate the"Chinese guideline for the clinical application of noninvasive imaging technology in accessing cancer therapy-related cardiovascular toxicity".Building upon the systematic evaluation of guidelines and the latest evidence-based medical research in the field of cardio-oncology domestically and abroad,and in conjunction with data derived from evidence-based medical research in China,this guideline proposes noninvasive imaging examination methods and monitoring strategies for CTR-CVT,aiming to further standardize and guide the clinical practice of multidisciplinary physicians specializing in cardio-oncology in China.
文摘Traditional laparoscopic liver cancer resection faces challenges,such as difficultiesin tumor localization and accurate marking of liver segments,as well as theinability to provide real-time intraoperative navigation.This approach falls shortof meeting the demands for precise and anatomical liver resection.The introductionof fluorescence imaging technology,particularly indocyanine green,hasdemonstrated significant advantages in visualizing bile ducts,tumor localization,segment staining,microscopic lesion display,margin examination,and lymphnode visualization.This technology addresses the inherent limitations oftraditional laparoscopy,which lacks direct tactile feedback,and is increasinglybecoming the standard in laparoscopic procedures.Guided by fluorescenceimaging technology,laparoscopic liver cancer resection is poised to become thepredominant technique for liver tumor removal,enhancing the accuracy,safetyand efficiency of the procedure.
文摘Skin imaging technologies such as dermoscopy, high-frequency ultrasound, reflective confocal microscopy and optical coherence tomography are developing rapidly in clinical application. Skin imaging technology can improve clinical diagnosis rate, and its non-invasiveness and repeatability make it occupy an irreplaceable position in clinical diagnosis. With the “booming development” of medical technology, skin imaging technology can improve clinical diagnosis rate. Researchers have made significant advances in assisting clinical diagnosis, prediction, and treatment of disease. This article reviews the application and progress of skin imaging in the diagnosis of psoriasis.
基金supported by grants from the National Key R&D Program of China,No.2017YFC0909200(to DC)the National Natural Science Foundation of China,No.62075225(to HZ)+1 种基金Zhejiang Provincial Medical Health Science and Technology Project,No.2023XY053(to ZP)Zhejiang Provincial Traditional Chinese Medical Science and Technology Project,No.2023ZL703(to ZP).
文摘Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.
文摘BACKGROUND Duodenal web is a rare congenital malformation,exceedingly uncommon in adults,and often misdiagnosed due to the subtle imaging features.CASE SUMMARY By analyzing the clinical diagnosis process and various imaging findings of a patient from our institution,this case report emphasizes the necessity of upper gastrointestinal series in diagnosing duodenal webs,outlines its typical radiographic features,and provides a literature review on the etiology,clinical presentation,and management of this condition.CONCLUSION This case report emphasizes the necessity of upper gastrointestinal series in diagnosing duodenal webs.
文摘With the reform and opening up entering a new era,China’s modern civilization and technology are“rolling forward”.In the medical field,innovative changes in radiology imaging technology have presented unprecedented value opportunities in tumor diagnosis.Therefore,this article explores the classification of radiological imaging techniques,specifically including X-ray imaging,Computed Tomography(CT),Magnetic Resonance Imaging(MRI),Positron Emission Tomography(PET),and ultrasound imaging.Furthermore,it analyzes the practical application of these key technologies in tumor diagnosis and propose new ideas.In the end,the advantages and characteristics of radiology imaging technology are evaluated,and two limitations are also pointed out,which deserves profound reflection.
基金Princess Nourah Bint Abdulrahman University Researchers Supporting Project number(PNURSP2025R826),Princess Nourah Bint Abdulrahman University,Riyadh,Saudi ArabiaNorthern Border University,Saudi Arabia,for supporting this work through project number(NBU-CRP-2025-2933).
文摘Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised models such as 3D U-Net perform well in this domain,but their accuracy significantly improves with appropriate preprocessing.This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model(GGMM)to T1 contrastenhanced MRI scans from the BraTS 2020 dataset.The Expectation-Maximization(EM)algorithm is employed to estimate parameters for four tissue classes,generating a new pre-segmented channel that enhances the training and performance of the 3DU-Net model.The proposed GGMM+3D U-Net framework achieved a Dice coefficient of 0.88 for whole tumor segmentation,outperforming both the standard multiscale 3D U-Net(0.84)and MMU-Net(0.85).It also delivered higher Intersection over Union(IoU)scores compared to models trained without preprocessing or with simpler GMM-based segmentation.These results,supported by qualitative visualizations,suggest that GGMM-based preprocessing should be integrated into brain tumor segmentation pipelines to optimize performance.
文摘Background:Quantum-enhanced medical imaging algorithms–quantum entanglement reconstruction,quantum noise suppression,and quantum beamforming–propose possible remedies for significant constraints in traditional diagnostic imaging,such as resolution,radiation efficiency,and real-time processing.Methods:This work used a mixed-methods strategy,including controlled phantom experiments,retrospective multi-center clinical data analysis,and quantum-classical hybrid processing to assess enhancements in resolution,dosage efficiency,and diagnostic confidence.Statistical validation included analysis of variance(ANOVA)and receiver-operating characteristic curve analysis,juxtaposing quantum-enhanced methodologies with conventional and deep learning approaches.Results:Quantum entanglement reconstruction enhanced magnetic resonance imaging spatial resolution by 33.2%(P<0.01),quantum noise suppression facilitated computed tomography scans with a 60%reduction in radiation,and quantum beamforming improved ultrasound contrast by 27%while preserving real-time processing(<2 ms delay).Inter-reader variability(12%in Diagnostic Confidence Scores)showed that systematic training is needed,even if the performance was better.The research presented(1)a reusable clinical quantum imaging framework,(2)enhanced hardware processes(field-programmable gate array/graphics processing unit acceleration),and(3)cost-benefit analyses demonstrating a 22-month return on investment breakeven point.Conclusion:Quantum-enhanced imaging has a lot of promise for use in medicine,especially in neurology and cancer.Future research should focus on multi-modal integration(e.g.,positron emission tomography–magnetic resonance imaging),cloud-based quantum simulations for enhanced accessibility,and extensive trials to confirm long-term diagnostic accuracy.This breakthrough gives healthcare systems a technology roadmap and a reason to spend money on quantum-enhanced diagnostics.
基金supported by the Shanghai Industrial Collaborative Innovation Fund(HCXBCY-2021-001)the Academy of Finland(349229)。
文摘Airborne hyperspectral imaging spectrometers have been used for Earth observation over the past four decades.Despite the high sensitivity of push-broom hyperspectral imagers,they experience limited swath and wavelength coverage.In this study,we report the development of a push-broom airborne multimodular imaging spectrometer(AMMIS)that spans ultraviolet(UV),visible near-infrared(VNIR),shortwave infrared(SWIR),and thermal infrared(TIR)wavelengths.As an integral part of China's HighResolution Earth Observation Program,AMMIS is intended for civilian applications and for validating key technologies for future spaceborne hyperspectral payloads.It has been mounted on aircraft platforms such as Y-5,Y-12,and XZ-60.Since 2016,AMMIS has been used to perform more than 30 flight campaigns and gather more than 200 TB of hyperspectral data.This study describes the system design,calibration techniques,performance tests,flight campaigns,and applications of the AMMIS.The system integrates UV,VNIR,SWIR,and TIR modules,which can be operated in combination or individually based on the application requirements.Each module includes three spectrometers,utilizing field-of-view(FOV)stitching technology to achieve a 40°FOV,thereby enhancing operational efficiency.We designed advanced optical systems for all modules,particularly for the TIR module,and employed cryogenic optical technology to maintain optical system stability at 100 K.Both laboratory and in-flight calibrations were conducted to improve preprocessing accuracy and produce high-quality hyperspectral data.The AMMIS features more than 1400 spectral bands,with spectral sampling intervals of 0.1 nm for UV,2.4 nm for VNIR,3 nm for SWIR,and 32 nm for TIR.In addition,the instantaneous fields of view(IFoVs)for the four modules were 0.5,0.25,0.5,and 1 mrad,respectively,with the VNIR module achieving an IFoV of 0.125 mrad in the high-spatial-resolution mode.This study reports on land-cover surveys,pollution gas detection,mineral exploration,coastal water detection,and plant investigations conducted using AMMIS,highlighting its excellent performance.Furthermore,we present three hyperspectral datasets with diverse scene distributions and categories suitable for developing artificial intelligence algorithms.This study paves the way for next-generation airborne and spaceborne hyperspectral payloads and serves as a valuable reference for hyperspectral sensor designers and data users.
基金co-supported by the China Postdoctoral Science Foundation(No.2024M754304)the Hunan Provincial Natural Science Foundation of China(No.2025JJ60072)。
文摘1.Introduction Infrared Imaging Missiles(IRIMs)are advanced weapons utilizing infrared technology for target detection and tracking.Their sensors capture thermal signatures and convert them into electronic images,enabling precise target identification and tracking.To a certain extent,the all-weather adaptability of IRIMs enables their effective operation across diverse environmental conditions,providing high targeting accuracy and cost efficiency.
基金Jinshan Science and Technology Committee(the data collection for this study was partially funded by the project),No.2021-3-05.
文摘BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)is a pivotal intervention for managing esophagogastric variceal bleeding in patients with chronic hepatic schistosomiasis.AIM To evaluate the efficacy of digital subtraction angiography image overlay tech-nology(DIT)in guiding the TIPS procedure.METHODS We conducted a retrospective analysis of patients who underwent TIPS at our hospital,comparing outcomes between an ultrasound-guided group and a DIT-guided group.Our analysis focused on the duration of the portosystemic shunt puncture,the number of punctures needed,the total surgical time,and various clinical indicators related to the surgery.RESULTS The study included 52 patients with esophagogastric varices due to chronic hepatic schistosomiasis.Results demonstrated that the DIT-guided group expe-rienced significantly shorter puncture times(P<0.001)and surgical durations(P=0.022)compared to the ultrasound-guided group.Additionally,postoperative assessments showed significant reductions in aspartate aminotransferase,B-type natriuretic peptide,and portal vein pressure in both groups.Notably,the DIT-guided group also showed significant reductions in total bilirubin(P=0.001)and alanine aminotransferase(P=0.023).CONCLUSION The use of DIT for guiding TIPS procedures highlights its potential to enhance procedural efficiency and reduce surgical times in the treatment of esophagogastric variceal bleeding in patients with chronic hepatic schistoso-miasis.
文摘Radiation‐induced heart disease(RIHD)is a heterogeneous,delayed,and potentially fatal adverse reaction to radiation that can damage all structures of the heart,including the pericardium,myocardium,coronary arteries,valves,and conduction system,leading to a series of diseases.Acute and chronic disease processes play a role in the development of RIHD,the onset times of which range from months to decades.However,the clinical manifestations of RIHD are usually insidious,overlap with several other diseases,and lack specificity.Cardiovascular imaging is essential for early diagnosis,follow‐up,and outcome assessment in patients with RIHD.This review first describes the pathogenesis and clinical manifestations of RIHD before providing an overview of the practical approaches and research advances in multimodal cardiovascular imaging in patients with RIHD,including echocardiography,cardiac magnetic resonance(CMR)and nuclear medicine,and cardiac computed tomography(CT).Then,the value of new cardiac imaging assessments for the early diagnosis of RIHD is described,particularly with relation to speckle‐tracking echocardiography,extracellular volume fraction assessment as a quantitative CMR technique,CMR myocardial strain assessment,positron emission tomography‐CT myocardial perfusion imaging,CT‐ECV,and CT strain assessment,amongst others.In addition,the advantages and disadvantages of each screening technique are compared with the aim of better guiding the follow‐up and diagnosis of subclinical RIHD and preventing cardiovascular events.
基金Fujian Provincial Health Technology Project,No.2020GGA079Natural Science Foundation of Fujian Province,No.2021J011380National Natural Science Foundation of China,No.62276146.
文摘Acute pancreatitis(AP)is a potentially life-threatening inflammatory disease of the pancreas,with clinical management determined by the severity of the disease.Diagnosis,severity prediction,and prognosis assessment of AP typically involve the use of imaging technologies,such as computed tomography,magnetic resonance imaging,and ultrasound,and scoring systems,including Ranson,Acute Physiology and Chronic Health Evaluation II,and Bedside Index for Severity in AP scores.Computed tomography is considered the gold standard imaging modality for AP due to its high sensitivity and specificity,while magnetic resonance imaging and ultrasound can provide additional information on biliary obstruction and vascular complications.Scoring systems utilize clinical and laboratory parameters to classify AP patients into mild,moderate,or severe categories,guiding treatment decisions,such as intensive care unit admission,early enteral feeding,and antibiotic use.Despite the central role of imaging technologies and scoring systems in AP management,these methods have limitations in terms of accuracy,reproducibility,practicality and economics.Recent advancements of artificial intelligence(AI)provide new opportunities to enhance their performance by analyzing vast amounts of clinical and imaging data.AI algorithms can analyze large amounts of clinical and imaging data,identify scoring system patterns,and predict the clinical course of disease.AI-based models have shown promising results in predicting the severity and mortality of AP,but further validation and standardization are required before widespread clinical application.In addition,understanding the correlation between these three technologies will aid in developing new methods that can accurately,sensitively,and specifically be used in the diagnosis,severity prediction,and prognosis assessment of AP through complementary advantages.
基金Projects(51774138,51804122,51904105)supported by the National Natural Science Foundation of ChinaProjects(E2021209148,E2021209052)supported by the Natural Science Foundation of Hebei Province,China。
文摘By utilizing wave velocity imaging technology,the uniaxial multi-stage loading test was conducted on siltstone to attain wave velocity imagings during rock fracture.Based on the time series parameters of acoustic emissions(AE),joint response characteristics of the velocity field and AE during rock fracture were analyzed.Moreover,the localization effect of damage during rock fracture was explored by applying wave velocity imagings.The experimental result showed that the wave velocity imagings enable three-dimensional(3-D)visualization of the extent and spatial position of damage to the rock.A damaged zone has a low wave velocity and a zone where the low wave velocity is concentrated tends to correspond to a severely damaged zone.AE parameters and wave velocity imagings depict the changes in activity of cracks during rock fracture from temporal and spatial perspectives,respectively:the activity of cracks is strengthened,and the rate of AE events increases during rock fracture;correspondingly,the low-velocity zones are gradually aggregated and their area gradually increases.From the wave velocity imagings,the damaged zones in rock were divided into an initially damaged zone,a progressively damaged zone,and a fractured zone.During rock fracture,the progressively damaged zone and the fractured zone both develop around the initially damaged zone,showing a typical localization effect of the damage.By capturing the spatial development trends of the progressively damaged zone and fractured zone in wave velocity imagings,the development of microfractures can be predicted,exerting practical significance for determining the position of the main fracture.
基金the support of the National Natural Science Foundation of China(Grant Nos.42207199,52179113,42272333)Zhejiang Postdoctoral Scientific Research Project(Grant Nos.ZJ2022155,ZJ2022156)。
文摘Three-dimensional(3D)printing technology is increasingly used in experimental research of geotechnical engineering.Compared to other materials,3D layer-by-layer printing specimens are extremely similar to the inherent properties of natural layered rock masses.In this paper,soft-hard interbedded rock masses with different dip angles were prepared based on 3D printing(3DP)sand core technology.Uniaxial compression creep tests were conducted to investigate its anisotropic creep behavior based on digital imaging correlation(DIC)technology.The results show that the anisotropic creep behavior of the 3DP soft-hard interbedded rock mass is mainly affected by the dip angles of the weak interlayer when the stress is at low levels.As the stress level increases,the effect of creep stress on its creep anisotropy increases significantly,and the dip angle is no longer the main factor.The minimum value of the long-term strength and creep failure strength always appears in the weak interlayer within 30°–60°,which explains why the failure of the layered rock mass is controlled by the weak interlayer and generally emerges at 45°.The tests results are verified by comparing with theoretical and other published studies.The feasibility of the 3DP soft-hard interbedded rock mass provides broad prospects and application values for 3DP technology in future experimental research.
基金supported by the National Key Research and Development Program(No.2019YFB2005503)。
文摘Aiming at the problem that the lattice feature exceeds the view field of the scanning electron microscope(SEM)measuring system,a new lattice measuring method is proposed based on integral imaging technology.When the system works,the SEM measuring system is equivalent to an integral image acquisition system.Firstly,a lattice measuring method is researched based on integral imaging theory.Secondly,the system parameters are calibrated by the VLSI lattice standard.Finally,the value of the lattice standard to be tested is determined based on the calibration parameters and the lattice measuring algorithm.The experimental results show that,compared with the traditional electron microscope measurement method,the relative error of the measured value of the algorithm is maintained within 0.2%,with the same level of measurement accuracy,but it expands the field of view of the electron microscope measurement system,which is suitable for the measurement of samples under high magnification.
基金supported by the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (No.17KJB150005 and No.17KJD510001)the Natural Science Foundation of Changzhou Institute of Technology (No.YN1507 and No.YN1611)+1 种基金Undergraduate Training Program for Innovation of Changzhou Institute of Technology (No.2017276Y)the National Natural Science Foundation of China (No.21273212)
文摘Photodissociation dynamics of dichlorodifluoromethane (CF2Cl2) around 235 nm has been studied using the time-sliced velocity map imaging technology in combination with the resonance enhanced multi-photon ionization technology. By measuring the raw images of chlorine atoms which are formed via one-photon dissociation of CF2Cl2, the speed and angular distributions can be directly obtained. The speed distribution of excited-state chlorine atoms consists of high translation energy (ET) and low ET components, which are related to direct dissociation on 3Q0 state and predissociation on the ground state induced by internal conversion, respectively. The speed distribution of ground-state chlorine atoms also consists of high ET and low ET components which are related to predissociation between 3Q0 and 1Q1 states and predissociation on the ground state induced by internal conversion, respectively. Radical dissociation channel is confirmed, nevertheless, secondary dissociation and three-body dissociation channels are excluded.
基金Supported by the PetroChina–China University of Petroleum (Beijing) Strategic Cooperation Project (ZLZX2020-04)。
文摘To solve the problem that the production of Mahu conglomerate reservoir is not up to expectation after the multi-cluster plus temporary plugging fracturing technology is applied in horizontal wells, stages 2–6 in the test well MaHW6285 are selected to carry out erosion tests with different pumping parameters. The downhole video imaging technology is used to monitor the degree of perforations erosion, and then the fracture initiation and proppant distribution of each cluster are analyzed. The results showed that proppant entered 76.7% of the perforations. The proppant was mainly distributed in a few perforation clusters, and the amount of proppant entered in most of the clusters was limited. The proppant distribution in Stage 4 was relatively uniform, and the fracture initiation of each cluster in the stage is more uniform. The proppant distribution in stages 2, 3, 5, and 6 was significantly uneven, and the uniform degree of fracture initiation in each cluster is low. More than 70% of the proppant dose in the stage entered clusters near the heel end, so the addition of diverters did not promote the uniform initiation of hydraulic fractures. There was a positive correlation between the amount of proppant added and the degree of perforations erosion, and the degree of perforations erosion ranged from 15% to 352%, with an average value of 74.5%, which was far higher than the statistical results of shale reservoir tests in North America. The use of 180° phase perforation(horizontal direction) can reduce the “Phase Bias” of perforations erosion, promote uniform perforations erosion and fluid inflow. The research results provide the basis for optimizing the pumping procedure, reducing the perforation erosion and improving the success rate of diversion.
文摘The Staring Area Imaging Technology(SAIT) satellite continuously "images" the target over a certain time range, and can realize continuous imaging and multi-angle imaging of the area of interest. It has the characteristics of flexible imaging parameter setting and fast image preprocessing speed, enabling dynamic target detection and tracking, super-resolution, surface 3 D model construction, night-time imaging and many other application tasks. Based on the technical characteristics of the SAIT satellite, this paper analyzes the challenges in satellite development and data processing, focuses on the quasi-realtime application of SAIT satellite data, and looks at the development trend of the SAIT satellite.
