A magnetic field sensor with a magnetic fluid(MF)-coated intermodal interferometer is proposed and experimentally demonstrated. The interferometer is formed by sandwiching a segment of single mode fiber(SMF) between a...A magnetic field sensor with a magnetic fluid(MF)-coated intermodal interferometer is proposed and experimentally demonstrated. The interferometer is formed by sandwiching a segment of single mode fiber(SMF) between a segment of multi-mode fiber(MMF) and a spherical structure. It can be considered as a cascade of the traditional SMF-MMF-SMF structure and MMF-SMF-sphere structure. The transmission spectral characteristics change with the variation of applied magnetic field. The experimental results exhibit that the magnetic field sensitivities for wavelength and transmission loss are 0.047 nm/m T and 0.215 d B/m T for the interference dip around 1 535.36 nm. For the interference dip around 1548.41 nm,the sensitivities are 0.077 nm/m T and 0.243 d B/m T. Simultaneous measurement can be realized according to the different spectral responses.展开更多
In this paper,a novel refractive index(RI) sensor is proposed based on the fused tapered special multi-mode fiber(SMMF).Firstly,a section of SMMF is spliced between two single-mode fibers(SMFs).Then,the SMMF is proces...In this paper,a novel refractive index(RI) sensor is proposed based on the fused tapered special multi-mode fiber(SMMF).Firstly,a section of SMMF is spliced between two single-mode fibers(SMFs).Then,the SMMF is processed by a fused tapering machine,and a tapered fiber structure is fabricated.Finally,a fused tapered SMMF sensor is obtained for measuring external RI.The RI sensing mechanism of tapered SMMF sensor is analyzed in detail.For different fused tapering lengths,the experimental results show that the RI sensitivity can be up to 444.517 81 nm/RIU in the RI range of 1.334 9—1.347 0.The RI sensitivity is increased with the increase of fused tapering length.Moreover,it has many advantages,including high sensitivity,compact structure,fast response and wide application range.So it can be used to measure the solution concentration in the fields of biochemistry,health care and food processing.展开更多
Multi-mode fiber(MMF)links are expected to greatly enhance capacity to cope with rapidly increasing data traffic in optical short-reach systems and networks.Recently,mode division multiplexing(MDM)over MMF has been pr...Multi-mode fiber(MMF)links are expected to greatly enhance capacity to cope with rapidly increasing data traffic in optical short-reach systems and networks.Recently,mode division multiplexing(MDM)over MMF has been proposed,in which different modes in MMF are utilized as spatial channels for data transmission.Stronglycoupled MDM techniques utilizing coherent detection and multiplex-input-multiplex-output(MIMO)digital signal processing(DSP)are complex and expensive for shortreach transmission.So the weakly-coupled approach by significantly suppressing mode coupling in the fiber and optical components has been proposed.In this way,the signals in each mode can be independently transmitted and received using conventional intensity modulation and direct detection(IM-DD).In this paper,we elaborate the key technologies to realize weakly-coupled MDM transmission over conventional MMF,including mode characteristic in MMF and weakly-coupled mode multiplexer/ demultiplexer(MUX/DEMUX).We also present the upto-date experimental results for weakly-coupled MDM transmission over conventional OM3 MMF.We show that weakly-coupled MDM scheme is promising for high-speed optical interconnections and bandwidth upgrade of already-deployed MMF links.展开更多
Carbon dots(CDs)-based composites have shown impressive performance in fields of information encryption and sensing,however,a great challenge is to simultaneously implement multi-mode luminescence and room-temperature...Carbon dots(CDs)-based composites have shown impressive performance in fields of information encryption and sensing,however,a great challenge is to simultaneously implement multi-mode luminescence and room-temperature phosphorescence(RTP)detection in single system due to the formidable synthesis.Herein,a multifunctional composite of Eu&CDs@p RHO has been designed by co-assembly strategy and prepared via a facile calcination and impregnation treatment.Eu&CDs@p RHO exhibits intense fluorescence(FL)and RTP coming from two individual luminous centers,Eu3+in the free pores and CDs in the interrupted structure of RHO zeolite.Unique four-mode color outputs including pink(Eu^(3+),ex.254 nm),light violet(CDs,ex.365 nm),blue(CDs,254 nm off),and green(CDs,365 nm off)could be realized,on the basis of it,a preliminary application of advanced information encoding has been demonstrated.Given the free pores of matrix and stable RTP in water of confined CDs,a visual RTP detection of Fe^(3+)ions is achieved with the detection limit as low as 9.8μmol/L.This work has opened up a new perspective for the strategic amalgamation of luminous vips with porous zeolite to construct the advanced functional materials.展开更多
Prostate cancer(PCa)is characterized by high incidence and propensity for easy metastasis,presenting significant challenges in clinical diagnosis and treatment.Tumor microenvironment(TME)-responsive nanomaterials prov...Prostate cancer(PCa)is characterized by high incidence and propensity for easy metastasis,presenting significant challenges in clinical diagnosis and treatment.Tumor microenvironment(TME)-responsive nanomaterials provide a promising prospect for imaging-guided precision therapy.Considering that tumor-derived alkaline phosphatase(ALP)is over-expressed in metastatic PCa,it makes a great chance to develop a theranostics system with ALP responsive in the TME.Herein,an ALP-responsive aggregationinduced emission luminogens(AIEgens)nanoprobe AMNF self-assembly was designed for enhancing the diagnosis and treatment of metastatic PCa.The nanoprobe exhibited self-aggregation in the presence of ALP resulted in aggregation-induced fluorescence,and enhanced accumulation and prolonged retention period at the tumor site.In terms of detection,the fluorescence(FL)/computed tomography(CT)/magnetic resonance(MR)multi-mode imaging effect of nanoprobe was significantly improved post-aggregation,enabling precise diagnosis through the amalgamation of multiple imaging modes.Enhanced CT/MR imaging can achieve assist preoperative tumor diagnosis,and enhanced FL imaging technology can achieve“intraoperative visual navigation”,showing its potential application value in clinical tumor detection and surgical guidance.In terms of treatment,AMNF showed strong absorption in the near infrared region after aggregation,which improved the photothermal treatment effect.Overall,our work developed an effective aggregation-enhanced theranostic strategy for ALP-related cancers.展开更多
Low-carbon smart parks achieve selfbalanced carbon emission and absorption through the cooperative scheduling of direct current(DC)-based distributed photovoltaic,energy storage units,and loads.Direct current power li...Low-carbon smart parks achieve selfbalanced carbon emission and absorption through the cooperative scheduling of direct current(DC)-based distributed photovoltaic,energy storage units,and loads.Direct current power line communication(DC-PLC)enables real-time data transmission on DC power lines.With traffic adaptation,DC-PLC can be integrated with other complementary media such as 5G to reduce transmission delay and improve reliability.However,traffic adaptation for DC-PLC and 5G integration still faces the challenges such as coupling between traffic admission control and traffic partition,dimensionality curse,and the ignorance of extreme event occurrence.To address these challenges,we propose a deep reinforcement learning(DRL)-based delay sensitive and reliable traffic adaptation algorithm(DSRTA)to minimize the total queuing delay under the constraints of traffic admission control,queuing delay,and extreme events occurrence probability.DSRTA jointly optimizes traffic admission control and traffic partition,and enables learning-based intelligent traffic adaptation.The long-term constraints are incorporated into both state and bound of drift-pluspenalty to achieve delay awareness and enforce reliability guarantee.Simulation results show that DSRTA has lower queuing delay and more reliable quality of service(QoS)guarantee than other state-of-the-art algorithms.展开更多
The remodeling of axonal connections following injury is an important feature driving functional recovery.The reticulospinal tract is an interesting descending motor tract that contains both excitatory and inhibitory ...The remodeling of axonal connections following injury is an important feature driving functional recovery.The reticulospinal tract is an interesting descending motor tract that contains both excitatory and inhibitory fibers.While the reticulospinal tract has been shown to be particularly prone to axonal growth and plasticity following injuries of the spinal cord,the differential capacities of excitatory and inhibitory fibers for plasticity remain unclear.As adaptive axonal plasticity involves a sophisticated interplay between excitatory and inhibitory input,we investigated in this study the plastic potential of glutamatergic(vGlut2)and GABAergic(vGat)fibers originating from the gigantocellular nucleus and the lateral paragigantocellular nucleus,two nuclei important for locomotor function.Using a combination of viral tracing,chemogenetic silencing,and AI-based kinematic analysis,we investigated plasticity and its impact on functional recovery within the first 3 weeks following injury,a period prone to neuronal remodeling.We demonstrate that,in this time frame,while vGlut2-positive fibers within the gigantocellular and lateral paragigantocellular nuclei rewire significantly following cervical spinal cord injury,vGat-positive fibers are rather unresponsive to injury.We also show that the acute silencing of excitatory axonal fibers which rewire in response to lesions of the spinal cord triggers a worsening of the functional recovery.Using kinematic analysis,we also pinpoint the locomotion features associated with the gigantocellular nucleus or lateral paragigantocellular nucleus during functional recovery.Overall,our study increases the understanding of the role of the gigantocellular and lateral paragigantocellular nuclei during functional recovery following spinal cord injury.展开更多
Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexib...Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexible fiber sensors.Through the preform-tofiber manufacturing technique,a variety of fiber sensors with complex functionalities spanning from the nanoscale to kilometer scale can be automated in a short time.Examples include temperature,acoustic,mechanical,chemical,biological,optoelectronic,and multifunctional sensors,which operate on diverse sensing principles such as resistance,capacitance,piezoelectricity,triboelectricity,photoelectricity,and thermoelectricity.This review outlines the principles of the thermal drawing process and provides a detailed overview of the latest advancements in various thermally drawn fiber sensors.Finally,the future developments of thermally drawn fiber sensors are discussed.展开更多
This paper considers the problem of time varying congestion pricing to determine optimal time-varying tolls at peak periods for a queuing network with the interactions between buses and private cars.Through the combin...This paper considers the problem of time varying congestion pricing to determine optimal time-varying tolls at peak periods for a queuing network with the interactions between buses and private cars.Through the combined applications of the space-time expanded network（STEN） and the conventional network equilibrium modeling techniques,a multi-class,multi-mode and multi-criteria traffic network equilibrium model is developed.Travelers of different classes have distinctive value of times（VOTs）,and travelers from the same class perceive their travel disutility or generalized costs on a route according to different weights of travel time and travel costs.Moreover,the symmetric cost function model is extended to deal with the interactions between buses and private cars.It is found that there exists a uniform（anonymous） link toll pattern which can drive a multi-class,multi-mode and multi-criteria user equilibrium flow pattern to a system optimum when the system＇s objective function is measured in terms of money.It is also found that the marginal cost pricing models with a symmetric travel cost function do not reflect the interactions between traffic flows of different road sections,and the obtained congestion pricing toll is smaller than the real value.展开更多
Gas Turbine Engines （GTEs） are vastly used for generation of mechanical power in a wide range of applications from airplane propulsion systems to stationary power plants. The gaspath components of a GTE are exposed ...Gas Turbine Engines （GTEs） are vastly used for generation of mechanical power in a wide range of applications from airplane propulsion systems to stationary power plants. The gaspath components of a GTE are exposed to harsh operating and ambient conditions, leading to several degradation mechanisms. Because GTE components are mostly inaccessible for direct measure- ments and their degradation levels must be inferred from the measurements of accessible parameters, it is a challenge to acquire reliable information on the degradation conditions of the parts in different fault modes. In this work, a data-driven fault detection and degradation estima- tion scheme is developed for GTE diagnostics based on an Adaptive Neuro-Fuzzy Inference System （ANFIS）. To verify the performance and accuracy of the developed diagnostic framework on GTE data, an ensemble of measurable gas path parameters has been generated by a high-fidelity GTE model under （a） diverse ambient conditions and control settings, （b） every possible combination of degradation symptoms, and （c） a broad range of signal to noise ratios. The results prove the competency of the developed framework in fault diagnostics and reveal the sensitivity of diagnostic results to measurement noise for different degradation symptoms.展开更多
For the multi-mode radar working in the modern electronicbattlefield, different working states of one single radar areprone to being classified as multiple emitters when adoptingtraditional classification methods to p...For the multi-mode radar working in the modern electronicbattlefield, different working states of one single radar areprone to being classified as multiple emitters when adoptingtraditional classification methods to process intercepted signals,which has a negative effect on signal classification. A classificationmethod based on spatial data mining is presented to address theabove challenge. Inspired by the idea of spatial data mining, theclassification method applies nuclear field to depicting the distributioninformation of pulse samples in feature space, and digs out thehidden cluster information by analyzing distribution characteristics.In addition, a membership-degree criterion to quantify the correlationamong all classes is established, which ensures classificationaccuracy of signal samples. Numerical experiments show that thepresented method can effectively prevent different working statesof multi-mode emitter from being classified as several emitters,and achieve higher classification accuracy.展开更多
A new multi-mode resistivity imaging sonde, with toroidal coils as source, can conduct three resistivity measurements: azimuthal resistivity, lateral resistivity, and bit resistivity measurements. Thus, the logging ti...A new multi-mode resistivity imaging sonde, with toroidal coils as source, can conduct three resistivity measurements: azimuthal resistivity, lateral resistivity, and bit resistivity measurements. Thus, the logging time and cost are greatly saved. The toroidal coils are simplified as an extended voltage dipole and the response equations are derived for a homogenous formation. Based on 3D FEM, the depth of investigation(DOI), vertical resolution, circumferential azimuthal capacity, borehole diameter, mud resistivity, thickness of target formation, and the resistivity of the surrounding formation and mud invasion are simulated. The results suggest that the three measurement modes of the new sonde are different in vertical resolutions and DOIs. The circumferential detection ability of the azimuth button depends on the contrast between the anomaly and formation resistivity and the open angle of the anomaly. Whether the borehole is truncated at the bit or not has a great influence on the simulation results. The borehole and mud invasion affect the apparent resistivity in all modes, but the effects of resistivity of surrounding formation and thickness of the target formation are only corrected for lateral resistivity measurement.展开更多
There are multiple operating modes in the real industrial process, and the collected data follow the complex multimodal distribution, so most traditional process monitoring methods are no longer applicable because the...There are multiple operating modes in the real industrial process, and the collected data follow the complex multimodal distribution, so most traditional process monitoring methods are no longer applicable because their presumptions are that sampled-data should obey the single Gaussian distribution or non-Gaussian distribution. In order to solve these problems, a novel weighted local standardization(WLS) strategy is proposed to standardize the multimodal data, which can eliminate the multi-mode characteristics of the collected data, and normalize them into unimodal data distribution. After detailed analysis of the raised data preprocessing strategy, a new algorithm using WLS strategy with support vector data description(SVDD) is put forward to apply for multi-mode monitoring process. Unlike the strategy of building multiple local models, the developed method only contains a model without the prior knowledge of multi-mode process. To demonstrate the proposed method's validity, it is applied to a numerical example and a Tennessee Eastman(TE) process. Finally, the simulation results show that the WLS strategy is very effective to standardize multimodal data, and the WLS-SVDD monitoring method has great advantages over the traditional SVDD and PCA combined with a local standardization strategy(LNS-PCA) in multi-mode process monitoring.展开更多
In mobile machinery,hydro-mechanical pumps are increasingly replaced by electronically controlled pumps to improve the automation level,but diversified control functions(e.g.,power limitation and pressure cut-off)are ...In mobile machinery,hydro-mechanical pumps are increasingly replaced by electronically controlled pumps to improve the automation level,but diversified control functions(e.g.,power limitation and pressure cut-off)are integrated into the electronic controller only from the pump level,leading to the potential instability of the overall system.To solve this problem,a multi-mode electrohydraulic load sensing(MELS)control scheme is proposed especially considering the switching stability from the system level,which includes four working modes of flow control,load sensing,power limitation,and pressure control.Depending on the actual working requirements,the switching rules for the different modes and the switching direction(i.e.,the modes can be switched bilaterally or unilaterally)are defined.The priority of different modes is also defined,from high to low:pressure control,power limitation,load sensing,and flow control.When multiple switching rules are satisfied at the same time,the system switches to the control mode with the highest priority.In addition,the switching stability between flow control and pressure control modes is analyzed,and the controller parameters that guarantee the switching stability are obtained.A comparative study is carried out based on a test rig with a 2-ton hydraulic excavator.The results show that the MELS controller can achieve the control functions of proper flow supplement,power limitation,and pressure cut-off,which has good stability performance when switching between different control modes.This research proposes the MELS control method that realizes the stability of multi-mode switching of the hydraulic system of mobile machinery under different working conditions.展开更多
The digital communication in a system of two multi-mode solid state chaotic lasers is investigated theoretically. If the usual method working well in a single-mode laser system is applied to a multi-mode laser system,...The digital communication in a system of two multi-mode solid state chaotic lasers is investigated theoretically. If the usual method working well in a single-mode laser system is applied to a multi-mode laser system, the memory effect of the two nearest digits can cause high rate of mistakes when the digits are decoded through the subtraction of receiver output from the transmittal. By introducing the deviations of two nearest maximum and minimum fluctuationsof the signal to decode the digit, the message can be decoded correctly. Also, this communication method does not critically depend on the quality of the chaotic synchronization of the two multi-mode lasers.展开更多
Multi-mode power internet of things(PIoT)combines various communication media to provide spatio-temporal coverage for low-carbon operation in smart park.Edge-end collaboration is feasible to achieve the full utilizati...Multi-mode power internet of things(PIoT)combines various communication media to provide spatio-temporal coverage for low-carbon operation in smart park.Edge-end collaboration is feasible to achieve the full utilization of heterogeneous resources and anti-eavesdropping.However,edge-end collaboration-based multi-mode PIoT faces challenges of mutual contradiction in communication and security quality of service(QoS)guarantee,inadaptability of resource management,and multi-mode access conflict.We propose an Adaptive learning based delAysensitive and seCure Edge-End Collaboration algorithm(ACE_(2))to optimize multi-mode channel selection and split device power into artificial noise(AN)transmission and data transmission for secure data delivery.ACE_(2) can achieve multi-attribute QoS guarantee,adaptive resource management and security enhancement,and access conflict elimination with the combined power of deep actor-critic(DAC),“win or learn fast(WoLF)”mechanism,and edge-end collaboration.Simulations demonstrate its superior performance in queuing delay,energy consumption,secrecy capacity,and adaptability to differentiated low-carbon services.展开更多
Based on the analysis of B3G evolution, the base-band processing chips for mobile terminals are introduced. Key technologies for multi-mode mobile terminal base-band chips are discussed. Terminal technologies are thou...Based on the analysis of B3G evolution, the base-band processing chips for mobile terminals are introduced. Key technologies for multi-mode mobile terminal base-band chips are discussed. Terminal technologies are thought to be the key of B3G, and terminal base-band chips are regarded as the core of terminal technologies. Therefore, a unified wireless development platform is required for the R&D of multi-mode mobile terminal base-band processing chips.展开更多
The classic multi-mode input shapers(MMISs)are valid to decrease multi-mode residual vibration of manipulators or robots simultaneously.But these input shapers cannot suppress more residual vibration with a quick resp...The classic multi-mode input shapers(MMISs)are valid to decrease multi-mode residual vibration of manipulators or robots simultaneously.But these input shapers cannot suppress more residual vibration with a quick response time when the frequency bandwidth of each mode vibration is very different.The methodologies and various types of multi-mode classic and hybrid input shaping control schemes with positive impulses were introduced in this paper.Six types of two-mode hybrid input shapers with positive impulses of a 3 degree of freedom robot were established.The ability and robustness of these two-mode hybrid input shapers to suppress residual vibration were analyzed by vibration response curve and sensitivity curve via numerical simulation.The response time of the zero vibration-zero vibration and derivative(ZV-ZVD)input shaper is the fastest,but the robustness is the least.The robustness of the zero vibration and derivative-extra insensitive(ZVD-EI)input shaper is the best,while the response time is the longest.According to the frequency bandwidth at each mode and required system response time,the most appropriate multi-mode hybrid input shaper(MMHIS)can be selected in order to improve response time as much as possible under the condition of suppressing more residual vibration.展开更多
基金supported by the National Natural Science Foundation of China(No.61475118)the National High-Tech Research and Development Program of China(863 Program)(No.2013AA014201)the Opened Fund of the State Key Laboratory on Integrated Optoelectronics(No.IOSKL2015KF06)
文摘A magnetic field sensor with a magnetic fluid(MF)-coated intermodal interferometer is proposed and experimentally demonstrated. The interferometer is formed by sandwiching a segment of single mode fiber(SMF) between a segment of multi-mode fiber(MMF) and a spherical structure. It can be considered as a cascade of the traditional SMF-MMF-SMF structure and MMF-SMF-sphere structure. The transmission spectral characteristics change with the variation of applied magnetic field. The experimental results exhibit that the magnetic field sensitivities for wavelength and transmission loss are 0.047 nm/m T and 0.215 d B/m T for the interference dip around 1 535.36 nm. For the interference dip around 1548.41 nm,the sensitivities are 0.077 nm/m T and 0.243 d B/m T. Simultaneous measurement can be realized according to the different spectral responses.
基金supported by the National Natural Science Foundation of China(Nos.61205068 and 61475133)the Hebei Province Science and Technology Support Program(Nos.15273304D and 14273301D)+1 种基金the College Youth Talent Project of Hebei Province(No.BJ2014057)the“Xin Rui Gong Cheng”Talent Project and the Excellent Youth Funds for School of Information Science and Engineering in Yanshan University(No.2014201)
文摘In this paper,a novel refractive index(RI) sensor is proposed based on the fused tapered special multi-mode fiber(SMMF).Firstly,a section of SMMF is spliced between two single-mode fibers(SMFs).Then,the SMMF is processed by a fused tapering machine,and a tapered fiber structure is fabricated.Finally,a fused tapered SMMF sensor is obtained for measuring external RI.The RI sensing mechanism of tapered SMMF sensor is analyzed in detail.For different fused tapering lengths,the experimental results show that the RI sensitivity can be up to 444.517 81 nm/RIU in the RI range of 1.334 9—1.347 0.The RI sensitivity is increased with the increase of fused tapering length.Moreover,it has many advantages,including high sensitivity,compact structure,fast response and wide application range.So it can be used to measure the solution concentration in the fields of biochemistry,health care and food processing.
基金the National Natural Science Foundation of China(Grant Nos.61771024,61627814,61505002,61690194 and 61605004)Fundamental Research Project of Shenzhen Science and Technology Foundation(Nos.JCYJ 20170412153729436 and 20170307172513653).
文摘Multi-mode fiber(MMF)links are expected to greatly enhance capacity to cope with rapidly increasing data traffic in optical short-reach systems and networks.Recently,mode division multiplexing(MDM)over MMF has been proposed,in which different modes in MMF are utilized as spatial channels for data transmission.Stronglycoupled MDM techniques utilizing coherent detection and multiplex-input-multiplex-output(MIMO)digital signal processing(DSP)are complex and expensive for shortreach transmission.So the weakly-coupled approach by significantly suppressing mode coupling in the fiber and optical components has been proposed.In this way,the signals in each mode can be independently transmitted and received using conventional intensity modulation and direct detection(IM-DD).In this paper,we elaborate the key technologies to realize weakly-coupled MDM transmission over conventional MMF,including mode characteristic in MMF and weakly-coupled mode multiplexer/ demultiplexer(MUX/DEMUX).We also present the upto-date experimental results for weakly-coupled MDM transmission over conventional OM3 MMF.We show that weakly-coupled MDM scheme is promising for high-speed optical interconnections and bandwidth upgrade of already-deployed MMF links.
基金supported by the National Natural Science Foundation of China(No.22288101)the 111 Project(No.B17020)。
文摘Carbon dots(CDs)-based composites have shown impressive performance in fields of information encryption and sensing,however,a great challenge is to simultaneously implement multi-mode luminescence and room-temperature phosphorescence(RTP)detection in single system due to the formidable synthesis.Herein,a multifunctional composite of Eu&CDs@p RHO has been designed by co-assembly strategy and prepared via a facile calcination and impregnation treatment.Eu&CDs@p RHO exhibits intense fluorescence(FL)and RTP coming from two individual luminous centers,Eu3+in the free pores and CDs in the interrupted structure of RHO zeolite.Unique four-mode color outputs including pink(Eu^(3+),ex.254 nm),light violet(CDs,ex.365 nm),blue(CDs,254 nm off),and green(CDs,365 nm off)could be realized,on the basis of it,a preliminary application of advanced information encoding has been demonstrated.Given the free pores of matrix and stable RTP in water of confined CDs,a visual RTP detection of Fe^(3+)ions is achieved with the detection limit as low as 9.8μmol/L.This work has opened up a new perspective for the strategic amalgamation of luminous vips with porous zeolite to construct the advanced functional materials.
基金supported by Natural Science Foundation of Jilin Province(No.SKL202302002)Key Research and Development project of Jilin Provincial Science and Technology Department(No.20210204142YY)+2 种基金The Science and Technology Development Program of Jilin Province(No.2020122256JC)Beijing Kechuang Medical Development Foundation Fund of China(No.KC2023-JX-0186BQ079)Talent Reserve Program(TRP),the First Hospital of Jilin University(No.JDYY-TRP-2024007)。
文摘Prostate cancer(PCa)is characterized by high incidence and propensity for easy metastasis,presenting significant challenges in clinical diagnosis and treatment.Tumor microenvironment(TME)-responsive nanomaterials provide a promising prospect for imaging-guided precision therapy.Considering that tumor-derived alkaline phosphatase(ALP)is over-expressed in metastatic PCa,it makes a great chance to develop a theranostics system with ALP responsive in the TME.Herein,an ALP-responsive aggregationinduced emission luminogens(AIEgens)nanoprobe AMNF self-assembly was designed for enhancing the diagnosis and treatment of metastatic PCa.The nanoprobe exhibited self-aggregation in the presence of ALP resulted in aggregation-induced fluorescence,and enhanced accumulation and prolonged retention period at the tumor site.In terms of detection,the fluorescence(FL)/computed tomography(CT)/magnetic resonance(MR)multi-mode imaging effect of nanoprobe was significantly improved post-aggregation,enabling precise diagnosis through the amalgamation of multiple imaging modes.Enhanced CT/MR imaging can achieve assist preoperative tumor diagnosis,and enhanced FL imaging technology can achieve“intraoperative visual navigation”,showing its potential application value in clinical tumor detection and surgical guidance.In terms of treatment,AMNF showed strong absorption in the near infrared region after aggregation,which improved the photothermal treatment effect.Overall,our work developed an effective aggregation-enhanced theranostic strategy for ALP-related cancers.
基金supported by the Science and Technology Project of State Grid Corporation of China under grant 52094021N010(5400-202199534A-0-5-ZN)。
文摘Low-carbon smart parks achieve selfbalanced carbon emission and absorption through the cooperative scheduling of direct current(DC)-based distributed photovoltaic,energy storage units,and loads.Direct current power line communication(DC-PLC)enables real-time data transmission on DC power lines.With traffic adaptation,DC-PLC can be integrated with other complementary media such as 5G to reduce transmission delay and improve reliability.However,traffic adaptation for DC-PLC and 5G integration still faces the challenges such as coupling between traffic admission control and traffic partition,dimensionality curse,and the ignorance of extreme event occurrence.To address these challenges,we propose a deep reinforcement learning(DRL)-based delay sensitive and reliable traffic adaptation algorithm(DSRTA)to minimize the total queuing delay under the constraints of traffic admission control,queuing delay,and extreme events occurrence probability.DSRTA jointly optimizes traffic admission control and traffic partition,and enables learning-based intelligent traffic adaptation.The long-term constraints are incorporated into both state and bound of drift-pluspenalty to achieve delay awareness and enforce reliability guarantee.Simulation results show that DSRTA has lower queuing delay and more reliable quality of service(QoS)guarantee than other state-of-the-art algorithms.
基金supported by the Deutsche Forschungsgemeinschaft(DFG),TRR274(Project ID 408885537,Sy Nergy,EXC 2145/ID 390857198,to FMB)。
文摘The remodeling of axonal connections following injury is an important feature driving functional recovery.The reticulospinal tract is an interesting descending motor tract that contains both excitatory and inhibitory fibers.While the reticulospinal tract has been shown to be particularly prone to axonal growth and plasticity following injuries of the spinal cord,the differential capacities of excitatory and inhibitory fibers for plasticity remain unclear.As adaptive axonal plasticity involves a sophisticated interplay between excitatory and inhibitory input,we investigated in this study the plastic potential of glutamatergic(vGlut2)and GABAergic(vGat)fibers originating from the gigantocellular nucleus and the lateral paragigantocellular nucleus,two nuclei important for locomotor function.Using a combination of viral tracing,chemogenetic silencing,and AI-based kinematic analysis,we investigated plasticity and its impact on functional recovery within the first 3 weeks following injury,a period prone to neuronal remodeling.We demonstrate that,in this time frame,while vGlut2-positive fibers within the gigantocellular and lateral paragigantocellular nuclei rewire significantly following cervical spinal cord injury,vGat-positive fibers are rather unresponsive to injury.We also show that the acute silencing of excitatory axonal fibers which rewire in response to lesions of the spinal cord triggers a worsening of the functional recovery.Using kinematic analysis,we also pinpoint the locomotion features associated with the gigantocellular nucleus or lateral paragigantocellular nucleus during functional recovery.Overall,our study increases the understanding of the role of the gigantocellular and lateral paragigantocellular nuclei during functional recovery following spinal cord injury.
基金supported by the National Key Research and Development Program of China(2023YFB3809800)the National Natural Science Foundation of China(52172249,52525601)+2 种基金the Chinese Academy of Sciences Talents Program(E2290701)the Jiangsu Province Talents Program(JSSCRC2023545)the Special Fund Project of Carbon Peaking Carbon Neutrality Science and Technology Innovation of Jiangsu Province(BE2022011).
文摘Flexible fiber sensors,However,traditional methods face challenges in fabricating low-cost,large-scale fiber sensors.In recent years,the thermal drawing process has rapidly advanced,offering a novel approach to flexible fiber sensors.Through the preform-tofiber manufacturing technique,a variety of fiber sensors with complex functionalities spanning from the nanoscale to kilometer scale can be automated in a short time.Examples include temperature,acoustic,mechanical,chemical,biological,optoelectronic,and multifunctional sensors,which operate on diverse sensing principles such as resistance,capacitance,piezoelectricity,triboelectricity,photoelectricity,and thermoelectricity.This review outlines the principles of the thermal drawing process and provides a detailed overview of the latest advancements in various thermally drawn fiber sensors.Finally,the future developments of thermally drawn fiber sensors are discussed.
基金The National High Technology Research and Development Program of China (863 Program) (No. 2007AA11Z202)the National Key Technology R & D Program of China during the 11th Five-Year Plan Period(No. 2006BAJ18B03)the Fundamental Research Funds for the Central Universities (No. DUT10RC(3) 112)
文摘This paper considers the problem of time varying congestion pricing to determine optimal time-varying tolls at peak periods for a queuing network with the interactions between buses and private cars.Through the combined applications of the space-time expanded network（STEN） and the conventional network equilibrium modeling techniques,a multi-class,multi-mode and multi-criteria traffic network equilibrium model is developed.Travelers of different classes have distinctive value of times（VOTs）,and travelers from the same class perceive their travel disutility or generalized costs on a route according to different weights of travel time and travel costs.Moreover,the symmetric cost function model is extended to deal with the interactions between buses and private cars.It is found that there exists a uniform（anonymous） link toll pattern which can drive a multi-class,multi-mode and multi-criteria user equilibrium flow pattern to a system optimum when the system＇s objective function is measured in terms of money.It is also found that the marginal cost pricing models with a symmetric travel cost function do not reflect the interactions between traffic flows of different road sections,and the obtained congestion pricing toll is smaller than the real value.
基金financially co-supported by Fond de Recherche Nature et Technologies (FRQNT) from the Quebec government in Canadathe Natural Sciences and Engineering Research Council (NSERC) of CanadaLife Prediction Technologies Inc. (LPTi) in Ottawa, Canada
文摘Gas Turbine Engines （GTEs） are vastly used for generation of mechanical power in a wide range of applications from airplane propulsion systems to stationary power plants. The gaspath components of a GTE are exposed to harsh operating and ambient conditions, leading to several degradation mechanisms. Because GTE components are mostly inaccessible for direct measure- ments and their degradation levels must be inferred from the measurements of accessible parameters, it is a challenge to acquire reliable information on the degradation conditions of the parts in different fault modes. In this work, a data-driven fault detection and degradation estima- tion scheme is developed for GTE diagnostics based on an Adaptive Neuro-Fuzzy Inference System （ANFIS）. To verify the performance and accuracy of the developed diagnostic framework on GTE data, an ensemble of measurable gas path parameters has been generated by a high-fidelity GTE model under （a） diverse ambient conditions and control settings, （b） every possible combination of degradation symptoms, and （c） a broad range of signal to noise ratios. The results prove the competency of the developed framework in fault diagnostics and reveal the sensitivity of diagnostic results to measurement noise for different degradation symptoms.
基金supported by the National Natural Science Foundation of China(61371172)the International S&T Cooperation Program of China(2015DFR10220)+1 种基金the Ocean Engineering Project of National Key Laboratory Foundation(1213)the Fundamental Research Funds for the Central Universities(HEUCF1608)
文摘For the multi-mode radar working in the modern electronicbattlefield, different working states of one single radar areprone to being classified as multiple emitters when adoptingtraditional classification methods to process intercepted signals,which has a negative effect on signal classification. A classificationmethod based on spatial data mining is presented to address theabove challenge. Inspired by the idea of spatial data mining, theclassification method applies nuclear field to depicting the distributioninformation of pulse samples in feature space, and digs out thehidden cluster information by analyzing distribution characteristics.In addition, a membership-degree criterion to quantify the correlationamong all classes is established, which ensures classificationaccuracy of signal samples. Numerical experiments show that thepresented method can effectively prevent different working statesof multi-mode emitter from being classified as several emitters,and achieve higher classification accuracy.
基金sponsored by Study on High-Precision Logging While Drilling Imaging Technology of Low-Permeability Reservoirs(No.2016ZX05021-002)
文摘A new multi-mode resistivity imaging sonde, with toroidal coils as source, can conduct three resistivity measurements: azimuthal resistivity, lateral resistivity, and bit resistivity measurements. Thus, the logging time and cost are greatly saved. The toroidal coils are simplified as an extended voltage dipole and the response equations are derived for a homogenous formation. Based on 3D FEM, the depth of investigation(DOI), vertical resolution, circumferential azimuthal capacity, borehole diameter, mud resistivity, thickness of target formation, and the resistivity of the surrounding formation and mud invasion are simulated. The results suggest that the three measurement modes of the new sonde are different in vertical resolutions and DOIs. The circumferential detection ability of the azimuth button depends on the contrast between the anomaly and formation resistivity and the open angle of the anomaly. Whether the borehole is truncated at the bit or not has a great influence on the simulation results. The borehole and mud invasion affect the apparent resistivity in all modes, but the effects of resistivity of surrounding formation and thickness of the target formation are only corrected for lateral resistivity measurement.
基金Project(61374140)supported by the National Natural Science Foundation of China
文摘There are multiple operating modes in the real industrial process, and the collected data follow the complex multimodal distribution, so most traditional process monitoring methods are no longer applicable because their presumptions are that sampled-data should obey the single Gaussian distribution or non-Gaussian distribution. In order to solve these problems, a novel weighted local standardization(WLS) strategy is proposed to standardize the multimodal data, which can eliminate the multi-mode characteristics of the collected data, and normalize them into unimodal data distribution. After detailed analysis of the raised data preprocessing strategy, a new algorithm using WLS strategy with support vector data description(SVDD) is put forward to apply for multi-mode monitoring process. Unlike the strategy of building multiple local models, the developed method only contains a model without the prior knowledge of multi-mode process. To demonstrate the proposed method's validity, it is applied to a numerical example and a Tennessee Eastman(TE) process. Finally, the simulation results show that the WLS strategy is very effective to standardize multimodal data, and the WLS-SVDD monitoring method has great advantages over the traditional SVDD and PCA combined with a local standardization strategy(LNS-PCA) in multi-mode process monitoring.
基金National Key Research and Development Program of China(Grant No.2020YFB2009702)National Natural Science Foundation of China(Grant Nos.52075055,U21A20124 and 52111530069)Chongqing Natural Science Foundation of China(Grant No.cstc2020jcyj-msxmX0780)。
文摘In mobile machinery,hydro-mechanical pumps are increasingly replaced by electronically controlled pumps to improve the automation level,but diversified control functions(e.g.,power limitation and pressure cut-off)are integrated into the electronic controller only from the pump level,leading to the potential instability of the overall system.To solve this problem,a multi-mode electrohydraulic load sensing(MELS)control scheme is proposed especially considering the switching stability from the system level,which includes four working modes of flow control,load sensing,power limitation,and pressure control.Depending on the actual working requirements,the switching rules for the different modes and the switching direction(i.e.,the modes can be switched bilaterally or unilaterally)are defined.The priority of different modes is also defined,from high to low:pressure control,power limitation,load sensing,and flow control.When multiple switching rules are satisfied at the same time,the system switches to the control mode with the highest priority.In addition,the switching stability between flow control and pressure control modes is analyzed,and the controller parameters that guarantee the switching stability are obtained.A comparative study is carried out based on a test rig with a 2-ton hydraulic excavator.The results show that the MELS controller can achieve the control functions of proper flow supplement,power limitation,and pressure cut-off,which has good stability performance when switching between different control modes.This research proposes the MELS control method that realizes the stability of multi-mode switching of the hydraulic system of mobile machinery under different working conditions.
基金The project supported by Natural Science Foundation of Jiangsu Province of China under Grant No.BK2001138
文摘The digital communication in a system of two multi-mode solid state chaotic lasers is investigated theoretically. If the usual method working well in a single-mode laser system is applied to a multi-mode laser system, the memory effect of the two nearest digits can cause high rate of mistakes when the digits are decoded through the subtraction of receiver output from the transmittal. By introducing the deviations of two nearest maximum and minimum fluctuationsof the signal to decode the digit, the message can be decoded correctly. Also, this communication method does not critically depend on the quality of the chaotic synchronization of the two multi-mode lasers.
基金supported by the Science and Technology Project of State Grid Corporation of China under Grant Number 52094021N010 (5400202199534A-0-5-ZN)
文摘Multi-mode power internet of things(PIoT)combines various communication media to provide spatio-temporal coverage for low-carbon operation in smart park.Edge-end collaboration is feasible to achieve the full utilization of heterogeneous resources and anti-eavesdropping.However,edge-end collaboration-based multi-mode PIoT faces challenges of mutual contradiction in communication and security quality of service(QoS)guarantee,inadaptability of resource management,and multi-mode access conflict.We propose an Adaptive learning based delAysensitive and seCure Edge-End Collaboration algorithm(ACE_(2))to optimize multi-mode channel selection and split device power into artificial noise(AN)transmission and data transmission for secure data delivery.ACE_(2) can achieve multi-attribute QoS guarantee,adaptive resource management and security enhancement,and access conflict elimination with the combined power of deep actor-critic(DAC),“win or learn fast(WoLF)”mechanism,and edge-end collaboration.Simulations demonstrate its superior performance in queuing delay,energy consumption,secrecy capacity,and adaptability to differentiated low-carbon services.
文摘Based on the analysis of B3G evolution, the base-band processing chips for mobile terminals are introduced. Key technologies for multi-mode mobile terminal base-band chips are discussed. Terminal technologies are thought to be the key of B3G, and terminal base-band chips are regarded as the core of terminal technologies. Therefore, a unified wireless development platform is required for the R&D of multi-mode mobile terminal base-band processing chips.
基金Project(LQ12E05008)supported by Natural Science Foundation of Zhejiang Province,ChinaProject(201708330107)supported by China Scholarship Council
文摘The classic multi-mode input shapers(MMISs)are valid to decrease multi-mode residual vibration of manipulators or robots simultaneously.But these input shapers cannot suppress more residual vibration with a quick response time when the frequency bandwidth of each mode vibration is very different.The methodologies and various types of multi-mode classic and hybrid input shaping control schemes with positive impulses were introduced in this paper.Six types of two-mode hybrid input shapers with positive impulses of a 3 degree of freedom robot were established.The ability and robustness of these two-mode hybrid input shapers to suppress residual vibration were analyzed by vibration response curve and sensitivity curve via numerical simulation.The response time of the zero vibration-zero vibration and derivative(ZV-ZVD)input shaper is the fastest,but the robustness is the least.The robustness of the zero vibration and derivative-extra insensitive(ZVD-EI)input shaper is the best,while the response time is the longest.According to the frequency bandwidth at each mode and required system response time,the most appropriate multi-mode hybrid input shaper(MMHIS)can be selected in order to improve response time as much as possible under the condition of suppressing more residual vibration.
