This paper presents a two-phase genetic algorithm (TPGA) based on the multi- parent genetic algorithm (MPGA). Through analysis we find MPGA will lead the population' s evol vement to diversity or convergence accor...This paper presents a two-phase genetic algorithm (TPGA) based on the multi- parent genetic algorithm (MPGA). Through analysis we find MPGA will lead the population' s evol vement to diversity or convergence according to the population size and the crossover size, so we make it run in different forms during the global and local optimization phases and then forms TPGA. The experiment results show that TPGA is very efficient for the optimization of low-dimension multi-modal functions, usually we can obtain all the global optimal solutions.展开更多
In this paper, a new algorithm for solving multi-modal function optimization problems-two-level subspace evolutionary algorithm is proposed. In the first level, the improved GT algorithm is used to do global recombina...In this paper, a new algorithm for solving multi-modal function optimization problems-two-level subspace evolutionary algorithm is proposed. In the first level, the improved GT algorithm is used to do global recombination search so that the whole population can be separated into several niches according to the position of solutions; then, in the second level, the niche evolutionary strategy is used for local search in the subspaces gotten in the first level till solutions of the problem are found. The new algorithm has been tested on some hard problems and some good results are obtained.展开更多
A novel immune genetic algorithm with the elitist selection and elitist crossover was proposed, which is called the immune genetic algorithm with the elitism （IGAE）. In IGAE, the new methods for computing antibody s...A novel immune genetic algorithm with the elitist selection and elitist crossover was proposed, which is called the immune genetic algorithm with the elitism （IGAE）. In IGAE, the new methods for computing antibody similarity, expected reproduction probability, and clonal selection probability were given. IGAE has three features. The first is that the similarities of two antibodies in structure and quality are all defined in the form of percentage, which helps to describe the similarity of two antibodies more accurately and to reduce the computational burden effectively. The second is that with the elitist selection and elitist crossover strategy IGAE is able to find the globally optimal solution of a given problem. The third is that the formula of expected reproduction probability of antibody can be adjusted through a parameter r, which helps to balance the population diversity and the convergence speed of IGAE so that IGAE can find the globally optimal solution of a given problem more rapidly. Two different complex multi-modal functions were selected to test the validity of IGAE. The experimental results show that IGAE can find the globally maximum/minimum values of the two functions rapidly. The experimental results also confirm that IGAE is of better performance in convergence speed, solution variation behavior, and computational efficiency compared with the canonical genetic algorithm with the elitism and the immune genetic algorithm with the information entropy and elitism.展开更多
Metal organic framework(MOF) assembled with coordination bonds has the disadvantage of poor stability that limits its application in the field of stationary phase,while covalent organic framework(COF)assembled through...Metal organic framework(MOF) assembled with coordination bonds has the disadvantage of poor stability that limits its application in the field of stationary phase,while covalent organic framework(COF)assembled through covalent bonds exhibits excellent structural stability.It has been shown that the stationary phases prepared by combining MOF and COF can make up for the poor stability of MOF@SiO_(2),and the MOF/COF composites have superior chromatographic separation performance.However,the traditional methods for preparing COF/MOF based stationary phases are generally solvent thermal synthesis.In this study,a green and low-cost synthesis method was proposed for the preparation of MOF/COF@SiO_(2) stationary phase.Firstly,COF@SiO_(2) was prepared in a choline chloride/ethylene glycol based deep eutectic solvent(DES).Secondly,another acid-base tunable DES prepared by mixing p-toluenesulfonic acid(PTSA)and 2-methylimidazole in different proportions was introduced as the reaction solvent and reactant for rapid synthesis of MOF/COF@SiO_(2).Compared with the toxic transition metal-based MOFs selected in most previous studies,a lightweight and non-toxic S-zone metal(calcium) based MOF was employed in this study.PTSA and calcium will form the calcium/oxygen-containing organic acid framework in acidic DES,which assembles with terephthalic acid dissolved in basic DES to form MOF.The strong hydrogen bonding effect of DES can facilitate rapid assembly of Ca-MOF.The obtained Ca-MOF/COF@SiO_(2) can be used for multi-mode chromatography to efficiently separate multiple isomeric/hydrophilic/hydrophobic analytes.The synthesis method of Ca-MOF/COF@SiO_(2) is green and mild,especially the use of acid-base tunable DES promotes the rapid synthesis of non-toxic Ca-MOF/COF@silica composites,which offers an innovative approach of greenly synthesizing novel MOF/COF stationary phases and extends their applications in the field of chromatography.展开更多
In multi-modal emotion recognition,excessive reliance on historical context often impedes the detection of emotional shifts,while modality heterogeneity and unimodal noise limit recognition performance.Existing method...In multi-modal emotion recognition,excessive reliance on historical context often impedes the detection of emotional shifts,while modality heterogeneity and unimodal noise limit recognition performance.Existing methods struggle to dynamically adjust cross-modal complementary strength to optimize fusion quality and lack effective mechanisms to model the dynamic evolution of emotions.To address these issues,we propose a multi-level dynamic gating and emotion transfer framework for multi-modal emotion recognition.A dynamic gating mechanism is applied across unimodal encoding,cross-modal alignment,and emotion transfer modeling,substantially improving noise robustness and feature alignment.First,we construct a unimodal encoder based on gated recurrent units and feature-selection gating to suppress intra-modal noise and enhance contextual representation.Second,we design a gated-attention crossmodal encoder that dynamically calibrates the complementary contributions of visual and audio modalities to the dominant textual features and eliminates redundant information.Finally,we introduce a gated enhanced emotion transfer module that explicitly models the temporal dependence of emotional evolution in dialogues via transfer gating and optimizes continuity modeling with a comparative learning loss.Experimental results demonstrate that the proposed method outperforms state-of-the-art models on the public MELD and IEMOCAP datasets.展开更多
Objective To develop a non-invasive predictive model for coronary artery stenosis severity based on adaptive multi-modal integration of traditional Chinese and western medicine data.Methods Clinical indicators,echocar...Objective To develop a non-invasive predictive model for coronary artery stenosis severity based on adaptive multi-modal integration of traditional Chinese and western medicine data.Methods Clinical indicators,echocardiographic data,traditional Chinese medicine(TCM)tongue manifestations,and facial features were collected from patients who underwent coro-nary computed tomography angiography(CTA)in the Cardiac Care Unit(CCU)of Shanghai Tenth People's Hospital between May 1,2023 and May 1,2024.An adaptive weighted multi-modal data fusion(AWMDF)model based on deep learning was constructed to predict the severity of coronary artery stenosis.The model was evaluated using metrics including accura-cy,precision,recall,F1 score,and the area under the receiver operating characteristic(ROC)curve(AUC).Further performance assessment was conducted through comparisons with six ensemble machine learning methods,data ablation,model component ablation,and various decision-level fusion strategies.Results A total of 158 patients were included in the study.The AWMDF model achieved ex-cellent predictive performance(AUC=0.973,accuracy=0.937,precision=0.937,recall=0.929,and F1 score=0.933).Compared with model ablation,data ablation experiments,and various traditional machine learning models,the AWMDF model demonstrated superior per-formance.Moreover,the adaptive weighting strategy outperformed alternative approaches,including simple weighting,averaging,voting,and fixed-weight schemes.Conclusion The AWMDF model demonstrates potential clinical value in the non-invasive prediction of coronary artery disease and could serve as a tool for clinical decision support.展开更多
Traditional Chinese medicine(TCM)demonstrates distinctive advantages in disease prevention and treatment.However,analyzing its biological mechanisms through the modern medical research paradigm of“single drug,single ...Traditional Chinese medicine(TCM)demonstrates distinctive advantages in disease prevention and treatment.However,analyzing its biological mechanisms through the modern medical research paradigm of“single drug,single target”presents significant challenges due to its holistic approach.Network pharmacology and its core theory of network targets connect drugs and diseases from a holistic and systematic perspective based on biological networks,overcoming the limitations of reductionist research models and showing considerable value in TCM research.Recent integration of network target computational and experimental methods with artificial intelligence(AI)and multi-modal multi-omics technologies has substantially enhanced network pharmacology methodology.The advancement in computational and experimental techniques provides complementary support for network target theory in decoding TCM principles.This review,centered on network targets,examines the progress of network target methods combined with AI in predicting disease molecular mechanisms and drug-target relationships,alongside the application of multi-modal multi-omics technologies in analyzing TCM formulae,syndromes,and toxicity.Looking forward,network target theory is expected to incorporate emerging technologies while developing novel approaches aligned with its unique characteristics,potentially leading to significant breakthroughs in TCM research and advancing scientific understanding and innovation in TCM.展开更多
The multi-modal characteristics of mineral particles play a pivotal role in enhancing the classification accuracy,which is critical for obtaining a profound understanding of the Earth's composition and ensuring ef...The multi-modal characteristics of mineral particles play a pivotal role in enhancing the classification accuracy,which is critical for obtaining a profound understanding of the Earth's composition and ensuring effective exploitation utilization of its resources.However,the existing methods for classifying mineral particles do not fully utilize these multi-modal features,thereby limiting the classification accuracy.Furthermore,when conventional multi-modal image classification methods are applied to planepolarized and cross-polarized sequence images of mineral particles,they encounter issues such as information loss,misaligned features,and challenges in spatiotemporal feature extraction.To address these challenges,we propose a multi-modal mineral particle polarization image classification network(MMGC-Net)for precise mineral particle classification.Initially,MMGC-Net employs a two-dimensional(2D)backbone network with shared parameters to extract features from two types of polarized images to ensure feature alignment.Subsequently,a cross-polarized intra-modal feature fusion module is designed to refine the spatiotemporal features from the extracted features of the cross-polarized sequence images.Ultimately,the inter-modal feature fusion module integrates the two types of modal features to enhance the classification precision.Quantitative and qualitative experimental results indicate that when compared with the current state-of-the-art multi-modal image classification methods,MMGC-Net demonstrates marked superiority in terms of mineral particle multi-modal feature learning and four classification evaluation metrics.It also demonstrates better stability than the existing models.展开更多
With the advent of the next-generation Air Traffic Control(ATC)system,there is growing interest in using Artificial Intelligence(AI)techniques to enhance Situation Awareness(SA)for ATC Controllers(ATCOs),i.e.,Intellig...With the advent of the next-generation Air Traffic Control(ATC)system,there is growing interest in using Artificial Intelligence(AI)techniques to enhance Situation Awareness(SA)for ATC Controllers(ATCOs),i.e.,Intelligent SA(ISA).However,the existing AI-based SA approaches often rely on unimodal data and lack a comprehensive description and benchmark of the ISA tasks utilizing multi-modal data for real-time ATC environments.To address this gap,by analyzing the situation awareness procedure of the ATCOs,the ISA task is refined to the processing of the two primary elements,i.e.,spoken instructions and flight trajectories.Subsequently,the ISA is further formulated into Controlling Intent Understanding(CIU)and Flight Trajectory Prediction(FTP)tasks.For the CIU task,an innovative automatic speech recognition and understanding framework is designed to extract the controlling intent from unstructured and continuous ATC communications.For the FTP task,the single-and multi-horizon FTP approaches are investigated to support the high-precision prediction of the situation evolution.A total of 32 unimodal/multi-modal advanced methods with extensive evaluation metrics are introduced to conduct the benchmarks on the real-world multi-modal ATC situation dataset.Experimental results demonstrate the effectiveness of AI-based techniques in enhancing ISA for the ATC environment.展开更多
A personalized outfit recommendation has emerged as a hot research topic in the fashion domain.However,existing recommendations do not fully exploit user style preferences.Typically,users prefer particular styles such...A personalized outfit recommendation has emerged as a hot research topic in the fashion domain.However,existing recommendations do not fully exploit user style preferences.Typically,users prefer particular styles such as casual and athletic styles,and consider attributes like color and texture when selecting outfits.To achieve personalized outfit recommendations in line with user style preferences,this paper proposes a personal style guided outfit recommendation with multi-modal fashion compatibility modeling,termed as PSGNet.Firstly,a style classifier is designed to categorize fashion images of various clothing types and attributes into distinct style categories.Secondly,a personal style prediction module extracts user style preferences by analyzing historical data.Then,to address the limitations of single-modal representations and enhance fashion compatibility,both fashion images and text data are leveraged to extract multi-modal features.Finally,PSGNet integrates these components through Bayesian personalized ranking(BPR)to unify the personal style and fashion compatibility,where the former is used as personal style features and guides the output of the personalized outfit recommendation tailored to the target user.Extensive experiments on large-scale datasets demonstrate that the proposed model is efficient on the personalized outfit recommendation.展开更多
The human striatum is essential for both lowand high-level functions and has been implicated in the pathophysiology of various prevalent disorders,including Parkinson's disease(PD)and schizophrenia(SCZ).It is know...The human striatum is essential for both lowand high-level functions and has been implicated in the pathophysiology of various prevalent disorders,including Parkinson's disease(PD)and schizophrenia(SCZ).It is known to consist of structurally and functionally divergent subdivisions.However,previous parcellations are based on a single neuroimaging modality,leaving the extent of the multi-modal organization of the striatum unknown.Here,we investigated the organization of the striatum across three modalities—resting-state functional connectivity,probabilistic diffusion tractography,and structural covariance—to provide a holistic convergent view of its structure and function.We found convergent clusters in the dorsal,dorsolateral,rostral,ventral,and caudal striatum.Functional characterization revealed the anterior striatum to be mainly associated with cognitive and emotional functions,while the caudal striatum was related to action execution.Interestingly,significant structural atrophy in the rostral and ventral striatum was common to both PD and SCZ,but atrophy in the dorsolateral striatum was specifically attributable to PD.Our study revealed a cross-modal convergent organization of the striatum,representing a fundamental topographical model that can be useful for investigating structural and functional variability in aging and in clinical conditions.展开更多
Multi-modal Named Entity Recognition(MNER)aims to better identify meaningful textual entities by integrating information from images.Previous work has focused on extracting visual semantics at a fine-grained level,or ...Multi-modal Named Entity Recognition(MNER)aims to better identify meaningful textual entities by integrating information from images.Previous work has focused on extracting visual semantics at a fine-grained level,or obtaining entity related external knowledge from knowledge bases or Large Language Models(LLMs).However,these approaches ignore the poor semantic correlation between visual and textual modalities in MNER datasets and do not explore different multi-modal fusion approaches.In this paper,we present MMAVK,a multi-modal named entity recognition model with auxiliary visual knowledge and word-level fusion,which aims to leverage the Multi-modal Large Language Model(MLLM)as an implicit knowledge base.It also extracts vision-based auxiliary knowledge from the image formore accurate and effective recognition.Specifically,we propose vision-based auxiliary knowledge generation,which guides the MLLM to extract external knowledge exclusively derived from images to aid entity recognition by designing target-specific prompts,thus avoiding redundant recognition and cognitive confusion caused by the simultaneous processing of image-text pairs.Furthermore,we employ a word-level multi-modal fusion mechanism to fuse the extracted external knowledge with each word-embedding embedded from the transformerbased encoder.Extensive experimental results demonstrate that MMAVK outperforms or equals the state-of-the-art methods on the two classical MNER datasets,even when the largemodels employed have significantly fewer parameters than other baselines.展开更多
Multi-modal knowledge graph completion(MMKGC)aims to complete missing entities or relations in multi-modal knowledge graphs,thereby discovering more previously unknown triples.Due to the continuous growth of data and ...Multi-modal knowledge graph completion(MMKGC)aims to complete missing entities or relations in multi-modal knowledge graphs,thereby discovering more previously unknown triples.Due to the continuous growth of data and knowledge and the limitations of data sources,the visual knowledge within the knowledge graphs is generally of low quality,and some entities suffer from the issue of missing visual modality.Nevertheless,previous studies of MMKGC have primarily focused on how to facilitate modality interaction and fusion while neglecting the problems of low modality quality and modality missing.In this case,mainstream MMKGC models only use pre-trained visual encoders to extract features and transfer the semantic information to the joint embeddings through modal fusion,which inevitably suffers from problems such as error propagation and increased uncertainty.To address these problems,we propose a Multi-modal knowledge graph Completion model based on Super-resolution and Detailed Description Generation(MMCSD).Specifically,we leverage a pre-trained residual network to enhance the resolution and improve the quality of the visual modality.Moreover,we design multi-level visual semantic extraction and entity description generation,thereby further extracting entity semantics from structural triples and visual images.Meanwhile,we train a variational multi-modal auto-encoder and utilize a pre-trained multi-modal language model to complement the missing visual features.We conducted experiments on FB15K-237 and DB13K,and the results showed that MMCSD can effectively perform MMKGC and achieve state-of-the-art performance.展开更多
Integrating multiple medical imaging techniques,including Magnetic Resonance Imaging(MRI),Computed Tomography,Positron Emission Tomography(PET),and ultrasound,provides a comprehensive view of the patient health status...Integrating multiple medical imaging techniques,including Magnetic Resonance Imaging(MRI),Computed Tomography,Positron Emission Tomography(PET),and ultrasound,provides a comprehensive view of the patient health status.Each of these methods contributes unique diagnostic insights,enhancing the overall assessment of patient condition.Nevertheless,the amalgamation of data from multiple modalities presents difficulties due to disparities in resolution,data collection methods,and noise levels.While traditional models like Convolutional Neural Networks(CNNs)excel in single-modality tasks,they struggle to handle multi-modal complexities,lacking the capacity to model global relationships.This research presents a novel approach for examining multi-modal medical imagery using a transformer-based system.The framework employs self-attention and cross-attention mechanisms to synchronize and integrate features across various modalities.Additionally,it shows resilience to variations in noise and image quality,making it adaptable for real-time clinical use.To address the computational hurdles linked to transformer models,particularly in real-time clinical applications in resource-constrained environments,several optimization techniques have been integrated to boost scalability and efficiency.Initially,a streamlined transformer architecture was adopted to minimize the computational load while maintaining model effectiveness.Methods such as model pruning,quantization,and knowledge distillation have been applied to reduce the parameter count and enhance the inference speed.Furthermore,efficient attention mechanisms such as linear or sparse attention were employed to alleviate the substantial memory and processing requirements of traditional self-attention operations.For further deployment optimization,researchers have implemented hardware-aware acceleration strategies,including the use of TensorRT and ONNX-based model compression,to ensure efficient execution on edge devices.These optimizations allow the approach to function effectively in real-time clinical settings,ensuring viability even in environments with limited resources.Future research directions include integrating non-imaging data to facilitate personalized treatment and enhancing computational efficiency for implementation in resource-limited environments.This study highlights the transformative potential of transformer models in multi-modal medical imaging,offering improvements in diagnostic accuracy and patient care outcomes.展开更多
In recent years,the analysis of encrypted network traffic has gained momentum due to the widespread use of Transport Layer Security and Quick UDP Internet Connections protocols,which complicate and prolong the analysi...In recent years,the analysis of encrypted network traffic has gained momentum due to the widespread use of Transport Layer Security and Quick UDP Internet Connections protocols,which complicate and prolong the analysis process.Classification models face challenges in understanding and classifying unknown traffic because of issues related to interpret ability and the representation of traffic data.To tackle these complexities,multi-modal representation learning can be employed to extract meaningful features and represent them in a lower-dimensional latent space.Recently,auto-encoder-based multi-modal representation techniques have shown superior performance in representing network traffic.By combining the advantages of multi-modal representation with efficient classifiers,we can develop robust network traffic classifiers.In this paper,we propose a novel multi-modal encoder-decoder model to create unified representations of network traffic,paired with a robust 1D-CNN(one-dimensional convolution neural network)classifier for effective traffic classification.The proposed model utilizes the ISCX Virtual Private Networknon Virtual Private Network 2016 datasets to extract general multi-modal representations and to train both shallow and deep learning models,such as Random Forest and the 1D-CNN model,for traffic classification.We compare these learning approaches based on the multi-modal representations generated from the autoencoder and the early feature fusion technique.For the classification task,both the Random Forest and 1D-CNN models,when trained on multimodal representations,achieve over 90%accuracy on a highly imbalanced dataset.展开更多
To address the challenge of missing modal information in entity alignment and to mitigate information loss or bias arising frommodal heterogeneity during fusion,while also capturing shared information acrossmodalities...To address the challenge of missing modal information in entity alignment and to mitigate information loss or bias arising frommodal heterogeneity during fusion,while also capturing shared information acrossmodalities,this paper proposes a Multi-modal Pre-synergistic Entity Alignmentmodel based on Cross-modalMutual Information Strategy Optimization(MPSEA).The model first employs independent encoders to process multi-modal features,including text,images,and numerical values.Next,a multi-modal pre-synergistic fusion mechanism integrates graph structural and visual modal features into the textual modality as preparatory information.This pre-fusion strategy enables unified perception of heterogeneous modalities at the model’s initial stage,reducing discrepancies during the fusion process.Finally,using cross-modal deep perception reinforcement learning,the model achieves adaptive multilevel feature fusion between modalities,supporting learningmore effective alignment strategies.Extensive experiments on multiple public datasets show that the MPSEA method achieves gains of up to 7% in Hits@1 and 8.2% in MRR on the FBDB15K dataset,and up to 9.1% in Hits@1 and 7.7% in MRR on the FBYG15K dataset,compared to existing state-of-the-art methods.These results confirm the effectiveness of the proposed model.展开更多
As the number and complexity of sensors in autonomous vehicles continue to rise,multimodal fusionbased object detection algorithms are increasingly being used to detect 3D environmental information,significantly advan...As the number and complexity of sensors in autonomous vehicles continue to rise,multimodal fusionbased object detection algorithms are increasingly being used to detect 3D environmental information,significantly advancing the development of perception technology in autonomous driving.To further promote the development of fusion algorithms and improve detection performance,this paper discusses the advantages and recent advancements of multimodal fusion-based object detection algorithms.Starting fromsingle-modal sensor detection,the paper provides a detailed overview of typical sensors used in autonomous driving and introduces object detection methods based on images and point clouds.For image-based detection methods,they are categorized into monocular detection and binocular detection based on different input types.For point cloud-based detection methods,they are classified into projection-based,voxel-based,point cluster-based,pillar-based,and graph structure-based approaches based on the technical pathways for processing point cloud features.Additionally,multimodal fusion algorithms are divided into Camera-LiDAR fusion,Camera-Radar fusion,Camera-LiDAR-Radar fusion,and other sensor fusion methods based on the types of sensors involved.Furthermore,the paper identifies five key future research directions in this field,aiming to provide insights for researchers engaged in multimodal fusion-based object detection algorithms and to encourage broader attention to the research and application of multimodal fusion-based object detection.展开更多
The primary objective of Chinese spelling correction(CSC)is to detect and correct erroneous characters in Chinese text,which can result from various factors,such as inaccuracies in pinyin representation,character rese...The primary objective of Chinese spelling correction(CSC)is to detect and correct erroneous characters in Chinese text,which can result from various factors,such as inaccuracies in pinyin representation,character resemblance,and semantic discrepancies.However,existing methods often struggle to fully address these types of errors,impacting the overall correction accuracy.This paper introduces a multi-modal feature encoder designed to efficiently extract features from three distinct modalities:pinyin,semantics,and character morphology.Unlike previous methods that rely on direct fusion or fixed-weight summation to integrate multi-modal information,our approach employs a multi-head attention mechanism to focuse more on relevant modal information while dis-regarding less pertinent data.To prevent issues such as gradient explosion or vanishing,the model incorporates a residual connection of the original text vector for fine-tuning.This approach ensures robust model performance by maintaining essential linguistic details throughout the correction process.Experimental evaluations on the SIGHAN benchmark dataset demonstrate that the pro-posed model outperforms baseline approaches across various metrics and datasets,confirming its effectiveness and feasibility.展开更多
BACKGROUND Stress ulcers are common complications in critically ill patients,with a higher incidence observed in older patients following gastrointestinal surgery.This study aimed to develop and evaluate the effective...BACKGROUND Stress ulcers are common complications in critically ill patients,with a higher incidence observed in older patients following gastrointestinal surgery.This study aimed to develop and evaluate the effectiveness of a multi-modal intervention protocol to prevent stress ulcers in this high-risk population.AIM To assess the impact of a multi-modal intervention on preventing stress ulcers in older intensive care unit(ICU)patients postoperatively.METHODS A randomized controlled trial involving critically ill patients(aged≥65 years)admitted to the ICU after gastrointestinal surgery was conducted.Patients were randomly assigned to either the intervention group,which received a multimodal stress ulcer prevention protocol,or the control group,which received standard care.The primary outcome measure was the incidence of stress ulcers.The secondary outcomes included ulcer healing time,complication rates,and length of hospital stay.RESULTS A total of 200 patients(100 in each group)were included in this study.The intervention group exhibited a significantly lower incidence of stress ulcers than the control group(15%vs 30%,P<0.01).Additionally,the intervention group demonstrated shorter ulcer healing times(mean 5.2 vs 7.8 days,P<0.05),lower complication rates(10%vs 22%,P<0.05),and reduced length of hospital stay(mean 12.3 vs 15.7 days,P<0.05).CONCLUSION This multi-modal intervention protocol significantly reduced the incidence of stress ulcers and improved clinical outcomes in critically ill older patients after gastrointestinal surgery.This comprehensive approach may provide a valuable strategy for managing high-risk populations in intensive care settings.展开更多
基金Supported by the National Natural Science Foundation of China (70071042,60073043,60133010)
文摘This paper presents a two-phase genetic algorithm (TPGA) based on the multi- parent genetic algorithm (MPGA). Through analysis we find MPGA will lead the population' s evol vement to diversity or convergence according to the population size and the crossover size, so we make it run in different forms during the global and local optimization phases and then forms TPGA. The experiment results show that TPGA is very efficient for the optimization of low-dimension multi-modal functions, usually we can obtain all the global optimal solutions.
基金Supported by the National Natural Science Foundation of China (70071042,60073043,60133010)
文摘In this paper, a new algorithm for solving multi-modal function optimization problems-two-level subspace evolutionary algorithm is proposed. In the first level, the improved GT algorithm is used to do global recombination search so that the whole population can be separated into several niches according to the position of solutions; then, in the second level, the niche evolutionary strategy is used for local search in the subspaces gotten in the first level till solutions of the problem are found. The new algorithm has been tested on some hard problems and some good results are obtained.
基金Project(50275150) supported by the National Natural Science Foundation of ChinaProjects(20040533035, 20070533131) supported by the National Research Foundation for the Doctoral Program of Higher Education of China
文摘A novel immune genetic algorithm with the elitist selection and elitist crossover was proposed, which is called the immune genetic algorithm with the elitism （IGAE）. In IGAE, the new methods for computing antibody similarity, expected reproduction probability, and clonal selection probability were given. IGAE has three features. The first is that the similarities of two antibodies in structure and quality are all defined in the form of percentage, which helps to describe the similarity of two antibodies more accurately and to reduce the computational burden effectively. The second is that with the elitist selection and elitist crossover strategy IGAE is able to find the globally optimal solution of a given problem. The third is that the formula of expected reproduction probability of antibody can be adjusted through a parameter r, which helps to balance the population diversity and the convergence speed of IGAE so that IGAE can find the globally optimal solution of a given problem more rapidly. Two different complex multi-modal functions were selected to test the validity of IGAE. The experimental results show that IGAE can find the globally maximum/minimum values of the two functions rapidly. The experimental results also confirm that IGAE is of better performance in convergence speed, solution variation behavior, and computational efficiency compared with the canonical genetic algorithm with the elitism and the immune genetic algorithm with the information entropy and elitism.
基金supported by National Natural Science Foundation of China (Nos.21906124,32302202)Natural Science Foundation of Hubei Province (No.2017CFB220)Natural Science Foundation of Shandong Province (No.ZR2023MH278)。
文摘Metal organic framework(MOF) assembled with coordination bonds has the disadvantage of poor stability that limits its application in the field of stationary phase,while covalent organic framework(COF)assembled through covalent bonds exhibits excellent structural stability.It has been shown that the stationary phases prepared by combining MOF and COF can make up for the poor stability of MOF@SiO_(2),and the MOF/COF composites have superior chromatographic separation performance.However,the traditional methods for preparing COF/MOF based stationary phases are generally solvent thermal synthesis.In this study,a green and low-cost synthesis method was proposed for the preparation of MOF/COF@SiO_(2) stationary phase.Firstly,COF@SiO_(2) was prepared in a choline chloride/ethylene glycol based deep eutectic solvent(DES).Secondly,another acid-base tunable DES prepared by mixing p-toluenesulfonic acid(PTSA)and 2-methylimidazole in different proportions was introduced as the reaction solvent and reactant for rapid synthesis of MOF/COF@SiO_(2).Compared with the toxic transition metal-based MOFs selected in most previous studies,a lightweight and non-toxic S-zone metal(calcium) based MOF was employed in this study.PTSA and calcium will form the calcium/oxygen-containing organic acid framework in acidic DES,which assembles with terephthalic acid dissolved in basic DES to form MOF.The strong hydrogen bonding effect of DES can facilitate rapid assembly of Ca-MOF.The obtained Ca-MOF/COF@SiO_(2) can be used for multi-mode chromatography to efficiently separate multiple isomeric/hydrophilic/hydrophobic analytes.The synthesis method of Ca-MOF/COF@SiO_(2) is green and mild,especially the use of acid-base tunable DES promotes the rapid synthesis of non-toxic Ca-MOF/COF@silica composites,which offers an innovative approach of greenly synthesizing novel MOF/COF stationary phases and extends their applications in the field of chromatography.
基金funded by“the Fanying Special Program of the National Natural Science Foundation of China,grant number 62341307”“the Scientific research project of Jiangxi Provincial Department of Education,grant number GJJ200839”“theDoctoral startup fund of JiangxiUniversity of Technology,grant number 205200100402”.
文摘In multi-modal emotion recognition,excessive reliance on historical context often impedes the detection of emotional shifts,while modality heterogeneity and unimodal noise limit recognition performance.Existing methods struggle to dynamically adjust cross-modal complementary strength to optimize fusion quality and lack effective mechanisms to model the dynamic evolution of emotions.To address these issues,we propose a multi-level dynamic gating and emotion transfer framework for multi-modal emotion recognition.A dynamic gating mechanism is applied across unimodal encoding,cross-modal alignment,and emotion transfer modeling,substantially improving noise robustness and feature alignment.First,we construct a unimodal encoder based on gated recurrent units and feature-selection gating to suppress intra-modal noise and enhance contextual representation.Second,we design a gated-attention crossmodal encoder that dynamically calibrates the complementary contributions of visual and audio modalities to the dominant textual features and eliminates redundant information.Finally,we introduce a gated enhanced emotion transfer module that explicitly models the temporal dependence of emotional evolution in dialogues via transfer gating and optimizes continuity modeling with a comparative learning loss.Experimental results demonstrate that the proposed method outperforms state-of-the-art models on the public MELD and IEMOCAP datasets.
基金Construction Program of the Key Discipline of State Administration of Traditional Chinese Medicine of China(ZYYZDXK-2023069)Research Project of Shanghai Municipal Health Commission (2024QN018)Shanghai University of Traditional Chinese Medicine Science and Technology Development Program (23KFL005)。
文摘Objective To develop a non-invasive predictive model for coronary artery stenosis severity based on adaptive multi-modal integration of traditional Chinese and western medicine data.Methods Clinical indicators,echocardiographic data,traditional Chinese medicine(TCM)tongue manifestations,and facial features were collected from patients who underwent coro-nary computed tomography angiography(CTA)in the Cardiac Care Unit(CCU)of Shanghai Tenth People's Hospital between May 1,2023 and May 1,2024.An adaptive weighted multi-modal data fusion(AWMDF)model based on deep learning was constructed to predict the severity of coronary artery stenosis.The model was evaluated using metrics including accura-cy,precision,recall,F1 score,and the area under the receiver operating characteristic(ROC)curve(AUC).Further performance assessment was conducted through comparisons with six ensemble machine learning methods,data ablation,model component ablation,and various decision-level fusion strategies.Results A total of 158 patients were included in the study.The AWMDF model achieved ex-cellent predictive performance(AUC=0.973,accuracy=0.937,precision=0.937,recall=0.929,and F1 score=0.933).Compared with model ablation,data ablation experiments,and various traditional machine learning models,the AWMDF model demonstrated superior per-formance.Moreover,the adaptive weighting strategy outperformed alternative approaches,including simple weighting,averaging,voting,and fixed-weight schemes.Conclusion The AWMDF model demonstrates potential clinical value in the non-invasive prediction of coronary artery disease and could serve as a tool for clinical decision support.
文摘Traditional Chinese medicine(TCM)demonstrates distinctive advantages in disease prevention and treatment.However,analyzing its biological mechanisms through the modern medical research paradigm of“single drug,single target”presents significant challenges due to its holistic approach.Network pharmacology and its core theory of network targets connect drugs and diseases from a holistic and systematic perspective based on biological networks,overcoming the limitations of reductionist research models and showing considerable value in TCM research.Recent integration of network target computational and experimental methods with artificial intelligence(AI)and multi-modal multi-omics technologies has substantially enhanced network pharmacology methodology.The advancement in computational and experimental techniques provides complementary support for network target theory in decoding TCM principles.This review,centered on network targets,examines the progress of network target methods combined with AI in predicting disease molecular mechanisms and drug-target relationships,alongside the application of multi-modal multi-omics technologies in analyzing TCM formulae,syndromes,and toxicity.Looking forward,network target theory is expected to incorporate emerging technologies while developing novel approaches aligned with its unique characteristics,potentially leading to significant breakthroughs in TCM research and advancing scientific understanding and innovation in TCM.
基金supported by the National Natural Science Foundation of China(Grant Nos.62071315 and 62271336).
文摘The multi-modal characteristics of mineral particles play a pivotal role in enhancing the classification accuracy,which is critical for obtaining a profound understanding of the Earth's composition and ensuring effective exploitation utilization of its resources.However,the existing methods for classifying mineral particles do not fully utilize these multi-modal features,thereby limiting the classification accuracy.Furthermore,when conventional multi-modal image classification methods are applied to planepolarized and cross-polarized sequence images of mineral particles,they encounter issues such as information loss,misaligned features,and challenges in spatiotemporal feature extraction.To address these challenges,we propose a multi-modal mineral particle polarization image classification network(MMGC-Net)for precise mineral particle classification.Initially,MMGC-Net employs a two-dimensional(2D)backbone network with shared parameters to extract features from two types of polarized images to ensure feature alignment.Subsequently,a cross-polarized intra-modal feature fusion module is designed to refine the spatiotemporal features from the extracted features of the cross-polarized sequence images.Ultimately,the inter-modal feature fusion module integrates the two types of modal features to enhance the classification precision.Quantitative and qualitative experimental results indicate that when compared with the current state-of-the-art multi-modal image classification methods,MMGC-Net demonstrates marked superiority in terms of mineral particle multi-modal feature learning and four classification evaluation metrics.It also demonstrates better stability than the existing models.
基金supported by the National Natural Science Foundation of China(Nos.62371323,62401380,U2433217,U2333209,and U20A20161)Natural Science Foundation of Sichuan Province,China(Nos.2025ZNSFSC1476)+2 种基金Sichuan Science and Technology Program,China(Nos.2024YFG0010 and 2024ZDZX0046)the Institutional Research Fund from Sichuan University(Nos.2024SCUQJTX030)the Open Fund of Key Laboratory of Flight Techniques and Flight Safety,CAAC(Nos.GY2024-01A).
文摘With the advent of the next-generation Air Traffic Control(ATC)system,there is growing interest in using Artificial Intelligence(AI)techniques to enhance Situation Awareness(SA)for ATC Controllers(ATCOs),i.e.,Intelligent SA(ISA).However,the existing AI-based SA approaches often rely on unimodal data and lack a comprehensive description and benchmark of the ISA tasks utilizing multi-modal data for real-time ATC environments.To address this gap,by analyzing the situation awareness procedure of the ATCOs,the ISA task is refined to the processing of the two primary elements,i.e.,spoken instructions and flight trajectories.Subsequently,the ISA is further formulated into Controlling Intent Understanding(CIU)and Flight Trajectory Prediction(FTP)tasks.For the CIU task,an innovative automatic speech recognition and understanding framework is designed to extract the controlling intent from unstructured and continuous ATC communications.For the FTP task,the single-and multi-horizon FTP approaches are investigated to support the high-precision prediction of the situation evolution.A total of 32 unimodal/multi-modal advanced methods with extensive evaluation metrics are introduced to conduct the benchmarks on the real-world multi-modal ATC situation dataset.Experimental results demonstrate the effectiveness of AI-based techniques in enhancing ISA for the ATC environment.
基金Shanghai Frontier Science Research Center for Modern Textiles,Donghua University,ChinaOpen Project of Henan Key Laboratory of Intelligent Manufacturing of Mechanical Equipment,Zhengzhou University of Light Industry,China(No.IM202303)National Key Research and Development Program of China(No.2019YFB1706300)。
文摘A personalized outfit recommendation has emerged as a hot research topic in the fashion domain.However,existing recommendations do not fully exploit user style preferences.Typically,users prefer particular styles such as casual and athletic styles,and consider attributes like color and texture when selecting outfits.To achieve personalized outfit recommendations in line with user style preferences,this paper proposes a personal style guided outfit recommendation with multi-modal fashion compatibility modeling,termed as PSGNet.Firstly,a style classifier is designed to categorize fashion images of various clothing types and attributes into distinct style categories.Secondly,a personal style prediction module extracts user style preferences by analyzing historical data.Then,to address the limitations of single-modal representations and enhance fashion compatibility,both fashion images and text data are leveraged to extract multi-modal features.Finally,PSGNet integrates these components through Bayesian personalized ranking(BPR)to unify the personal style and fashion compatibility,where the former is used as personal style features and guides the output of the personalized outfit recommendation tailored to the target user.Extensive experiments on large-scale datasets demonstrate that the proposed model is efficient on the personalized outfit recommendation.
基金This work was supported by the Deutsche Forschungsgemeinschaft(GE 2835/1-1,El 816/4-1)the Helmholtz Portfolio Theme 4 Supercomputing and Modelling for the Human Brain'and the European Union's Horizon 2020 Research and Innovation Programme under Grant Agreement No.785907(HBP SGA2)We gratefully acknowledge financial support from the China Scholarship Council(201606750003).
文摘The human striatum is essential for both lowand high-level functions and has been implicated in the pathophysiology of various prevalent disorders,including Parkinson's disease(PD)and schizophrenia(SCZ).It is known to consist of structurally and functionally divergent subdivisions.However,previous parcellations are based on a single neuroimaging modality,leaving the extent of the multi-modal organization of the striatum unknown.Here,we investigated the organization of the striatum across three modalities—resting-state functional connectivity,probabilistic diffusion tractography,and structural covariance—to provide a holistic convergent view of its structure and function.We found convergent clusters in the dorsal,dorsolateral,rostral,ventral,and caudal striatum.Functional characterization revealed the anterior striatum to be mainly associated with cognitive and emotional functions,while the caudal striatum was related to action execution.Interestingly,significant structural atrophy in the rostral and ventral striatum was common to both PD and SCZ,but atrophy in the dorsolateral striatum was specifically attributable to PD.Our study revealed a cross-modal convergent organization of the striatum,representing a fundamental topographical model that can be useful for investigating structural and functional variability in aging and in clinical conditions.
基金funded by Research Project,grant number BHQ090003000X03.
文摘Multi-modal Named Entity Recognition(MNER)aims to better identify meaningful textual entities by integrating information from images.Previous work has focused on extracting visual semantics at a fine-grained level,or obtaining entity related external knowledge from knowledge bases or Large Language Models(LLMs).However,these approaches ignore the poor semantic correlation between visual and textual modalities in MNER datasets and do not explore different multi-modal fusion approaches.In this paper,we present MMAVK,a multi-modal named entity recognition model with auxiliary visual knowledge and word-level fusion,which aims to leverage the Multi-modal Large Language Model(MLLM)as an implicit knowledge base.It also extracts vision-based auxiliary knowledge from the image formore accurate and effective recognition.Specifically,we propose vision-based auxiliary knowledge generation,which guides the MLLM to extract external knowledge exclusively derived from images to aid entity recognition by designing target-specific prompts,thus avoiding redundant recognition and cognitive confusion caused by the simultaneous processing of image-text pairs.Furthermore,we employ a word-level multi-modal fusion mechanism to fuse the extracted external knowledge with each word-embedding embedded from the transformerbased encoder.Extensive experimental results demonstrate that MMAVK outperforms or equals the state-of-the-art methods on the two classical MNER datasets,even when the largemodels employed have significantly fewer parameters than other baselines.
基金funded by Research Project,grant number BHQ090003000X03。
文摘Multi-modal knowledge graph completion(MMKGC)aims to complete missing entities or relations in multi-modal knowledge graphs,thereby discovering more previously unknown triples.Due to the continuous growth of data and knowledge and the limitations of data sources,the visual knowledge within the knowledge graphs is generally of low quality,and some entities suffer from the issue of missing visual modality.Nevertheless,previous studies of MMKGC have primarily focused on how to facilitate modality interaction and fusion while neglecting the problems of low modality quality and modality missing.In this case,mainstream MMKGC models only use pre-trained visual encoders to extract features and transfer the semantic information to the joint embeddings through modal fusion,which inevitably suffers from problems such as error propagation and increased uncertainty.To address these problems,we propose a Multi-modal knowledge graph Completion model based on Super-resolution and Detailed Description Generation(MMCSD).Specifically,we leverage a pre-trained residual network to enhance the resolution and improve the quality of the visual modality.Moreover,we design multi-level visual semantic extraction and entity description generation,thereby further extracting entity semantics from structural triples and visual images.Meanwhile,we train a variational multi-modal auto-encoder and utilize a pre-trained multi-modal language model to complement the missing visual features.We conducted experiments on FB15K-237 and DB13K,and the results showed that MMCSD can effectively perform MMKGC and achieve state-of-the-art performance.
基金supported by the Deanship of Research and Graduate Studies at King Khalid University under Small Research Project grant number RGP1/139/45.
文摘Integrating multiple medical imaging techniques,including Magnetic Resonance Imaging(MRI),Computed Tomography,Positron Emission Tomography(PET),and ultrasound,provides a comprehensive view of the patient health status.Each of these methods contributes unique diagnostic insights,enhancing the overall assessment of patient condition.Nevertheless,the amalgamation of data from multiple modalities presents difficulties due to disparities in resolution,data collection methods,and noise levels.While traditional models like Convolutional Neural Networks(CNNs)excel in single-modality tasks,they struggle to handle multi-modal complexities,lacking the capacity to model global relationships.This research presents a novel approach for examining multi-modal medical imagery using a transformer-based system.The framework employs self-attention and cross-attention mechanisms to synchronize and integrate features across various modalities.Additionally,it shows resilience to variations in noise and image quality,making it adaptable for real-time clinical use.To address the computational hurdles linked to transformer models,particularly in real-time clinical applications in resource-constrained environments,several optimization techniques have been integrated to boost scalability and efficiency.Initially,a streamlined transformer architecture was adopted to minimize the computational load while maintaining model effectiveness.Methods such as model pruning,quantization,and knowledge distillation have been applied to reduce the parameter count and enhance the inference speed.Furthermore,efficient attention mechanisms such as linear or sparse attention were employed to alleviate the substantial memory and processing requirements of traditional self-attention operations.For further deployment optimization,researchers have implemented hardware-aware acceleration strategies,including the use of TensorRT and ONNX-based model compression,to ensure efficient execution on edge devices.These optimizations allow the approach to function effectively in real-time clinical settings,ensuring viability even in environments with limited resources.Future research directions include integrating non-imaging data to facilitate personalized treatment and enhancing computational efficiency for implementation in resource-limited environments.This study highlights the transformative potential of transformer models in multi-modal medical imaging,offering improvements in diagnostic accuracy and patient care outcomes.
文摘In recent years,the analysis of encrypted network traffic has gained momentum due to the widespread use of Transport Layer Security and Quick UDP Internet Connections protocols,which complicate and prolong the analysis process.Classification models face challenges in understanding and classifying unknown traffic because of issues related to interpret ability and the representation of traffic data.To tackle these complexities,multi-modal representation learning can be employed to extract meaningful features and represent them in a lower-dimensional latent space.Recently,auto-encoder-based multi-modal representation techniques have shown superior performance in representing network traffic.By combining the advantages of multi-modal representation with efficient classifiers,we can develop robust network traffic classifiers.In this paper,we propose a novel multi-modal encoder-decoder model to create unified representations of network traffic,paired with a robust 1D-CNN(one-dimensional convolution neural network)classifier for effective traffic classification.The proposed model utilizes the ISCX Virtual Private Networknon Virtual Private Network 2016 datasets to extract general multi-modal representations and to train both shallow and deep learning models,such as Random Forest and the 1D-CNN model,for traffic classification.We compare these learning approaches based on the multi-modal representations generated from the autoencoder and the early feature fusion technique.For the classification task,both the Random Forest and 1D-CNN models,when trained on multimodal representations,achieve over 90%accuracy on a highly imbalanced dataset.
基金partially supported by the National Natural Science Foundation of China under Grants 62471493 and 62402257(for conceptualization and investigation)partially supported by the Natural Science Foundation of Shandong Province,China under Grants ZR2023LZH017,ZR2024MF066,and 2023QF025(for formal analysis and validation)+1 种基金partially supported by the Open Foundation of Key Laboratory of Computing Power Network and Information Security,Ministry of Education,Qilu University of Technology(Shandong Academy of Sciences)under Grant 2023ZD010(for methodology and model design)partially supported by the Russian Science Foundation(RSF)Project under Grant 22-71-10095-P(for validation and results verification).
文摘To address the challenge of missing modal information in entity alignment and to mitigate information loss or bias arising frommodal heterogeneity during fusion,while also capturing shared information acrossmodalities,this paper proposes a Multi-modal Pre-synergistic Entity Alignmentmodel based on Cross-modalMutual Information Strategy Optimization(MPSEA).The model first employs independent encoders to process multi-modal features,including text,images,and numerical values.Next,a multi-modal pre-synergistic fusion mechanism integrates graph structural and visual modal features into the textual modality as preparatory information.This pre-fusion strategy enables unified perception of heterogeneous modalities at the model’s initial stage,reducing discrepancies during the fusion process.Finally,using cross-modal deep perception reinforcement learning,the model achieves adaptive multilevel feature fusion between modalities,supporting learningmore effective alignment strategies.Extensive experiments on multiple public datasets show that the MPSEA method achieves gains of up to 7% in Hits@1 and 8.2% in MRR on the FBDB15K dataset,and up to 9.1% in Hits@1 and 7.7% in MRR on the FBYG15K dataset,compared to existing state-of-the-art methods.These results confirm the effectiveness of the proposed model.
基金funded by the Yangtze River Delta Science and Technology Innovation Community Joint Research Project(2023CSJGG1600)the Natural Science Foundation of Anhui Province(2208085MF173)Wuhu“ChiZhu Light”Major Science and Technology Project(2023ZD01,2023ZD03).
文摘As the number and complexity of sensors in autonomous vehicles continue to rise,multimodal fusionbased object detection algorithms are increasingly being used to detect 3D environmental information,significantly advancing the development of perception technology in autonomous driving.To further promote the development of fusion algorithms and improve detection performance,this paper discusses the advantages and recent advancements of multimodal fusion-based object detection algorithms.Starting fromsingle-modal sensor detection,the paper provides a detailed overview of typical sensors used in autonomous driving and introduces object detection methods based on images and point clouds.For image-based detection methods,they are categorized into monocular detection and binocular detection based on different input types.For point cloud-based detection methods,they are classified into projection-based,voxel-based,point cluster-based,pillar-based,and graph structure-based approaches based on the technical pathways for processing point cloud features.Additionally,multimodal fusion algorithms are divided into Camera-LiDAR fusion,Camera-Radar fusion,Camera-LiDAR-Radar fusion,and other sensor fusion methods based on the types of sensors involved.Furthermore,the paper identifies five key future research directions in this field,aiming to provide insights for researchers engaged in multimodal fusion-based object detection algorithms and to encourage broader attention to the research and application of multimodal fusion-based object detection.
基金Supported by the National Natural Science Foundation of China(No.61472256,61170277)the Hujiang Foundation(No.A14006).
文摘The primary objective of Chinese spelling correction(CSC)is to detect and correct erroneous characters in Chinese text,which can result from various factors,such as inaccuracies in pinyin representation,character resemblance,and semantic discrepancies.However,existing methods often struggle to fully address these types of errors,impacting the overall correction accuracy.This paper introduces a multi-modal feature encoder designed to efficiently extract features from three distinct modalities:pinyin,semantics,and character morphology.Unlike previous methods that rely on direct fusion or fixed-weight summation to integrate multi-modal information,our approach employs a multi-head attention mechanism to focuse more on relevant modal information while dis-regarding less pertinent data.To prevent issues such as gradient explosion or vanishing,the model incorporates a residual connection of the original text vector for fine-tuning.This approach ensures robust model performance by maintaining essential linguistic details throughout the correction process.Experimental evaluations on the SIGHAN benchmark dataset demonstrate that the pro-posed model outperforms baseline approaches across various metrics and datasets,confirming its effectiveness and feasibility.
文摘BACKGROUND Stress ulcers are common complications in critically ill patients,with a higher incidence observed in older patients following gastrointestinal surgery.This study aimed to develop and evaluate the effectiveness of a multi-modal intervention protocol to prevent stress ulcers in this high-risk population.AIM To assess the impact of a multi-modal intervention on preventing stress ulcers in older intensive care unit(ICU)patients postoperatively.METHODS A randomized controlled trial involving critically ill patients(aged≥65 years)admitted to the ICU after gastrointestinal surgery was conducted.Patients were randomly assigned to either the intervention group,which received a multimodal stress ulcer prevention protocol,or the control group,which received standard care.The primary outcome measure was the incidence of stress ulcers.The secondary outcomes included ulcer healing time,complication rates,and length of hospital stay.RESULTS A total of 200 patients(100 in each group)were included in this study.The intervention group exhibited a significantly lower incidence of stress ulcers than the control group(15%vs 30%,P<0.01).Additionally,the intervention group demonstrated shorter ulcer healing times(mean 5.2 vs 7.8 days,P<0.05),lower complication rates(10%vs 22%,P<0.05),and reduced length of hospital stay(mean 12.3 vs 15.7 days,P<0.05).CONCLUSION This multi-modal intervention protocol significantly reduced the incidence of stress ulcers and improved clinical outcomes in critically ill older patients after gastrointestinal surgery.This comprehensive approach may provide a valuable strategy for managing high-risk populations in intensive care settings.
