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Interlocked covalent organic cages:Design,synthesis,and self-assembly
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作者 Bin Yao Yao Bu +3 位作者 Hongfei Sun Guowang Li Xianying Wu Wei Wang 《Chinese Chemical Letters》 2026年第1期92-105,共14页
Interlocked covalent organic cages have aesthetic skeletons endowed with structural and topological complexity.Their self-assembly provides a unique possibility to mimic the hierarchical self-assembly of biomacromolec... Interlocked covalent organic cages have aesthetic skeletons endowed with structural and topological complexity.Their self-assembly provides a unique possibility to mimic the hierarchical self-assembly of biomacromolecules.In recent years,significant progresses in interlocked covalent organic cages have been witnessed.Different topological structures have been fabricated via various non-template induced methods,and diverse weak interactions are demonstrated to play critical roles in guiding the formation of interlocked structures.Therefore,this article systematically summarizes the recent advances in interlocked covalent organic cages,especially their design,synthesis,and self-assembly properties.Depending on different types of chemical reactions,irreversible and reversible reactions are separately introduced.In each section,proper monomer selection,critical topology design,key driving forces as well as detailed interlocked mechanisms for the formation of interlocked structures,and their self-assembly behaviors in single crystals are discussed detailedly.Finally,the challenge and future development of interlocked covalent organic cages are briefly prospected. 展开更多
关键词 Mechanically interlocked molecules Chemical topology Dynamic covalent chemistry Non-covalent interactions Supramolecular chemistry
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Impact toughness,crack initiation and propagation mechanism of Ti6422 alloy with multi-level lamellar microstructure
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作者 Jie Shen Zhihao Zhang Jianxin Xie 《International Journal of Minerals,Metallurgy and Materials》 2026年第2期595-609,共15页
The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.... The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.By adjusting the furnace cooling time after solution treatment and the aging temperature,Ti6422 alloy samples were developed with a multi-level lamellar microstructure,in-cluding microscaleαcolonies and α_(p) lamellae,as well as nanoscale α_(s) phases.Extending the furnace cooling time after solution treatment at 920℃ for 1 h from 240 to 540 min,followed by aging at 600℃ for 6 h,increased the α_(p) lamella content,reduced the α_(s) phase content,expanded theαcolonies and α_(p) lamellae size,and improved the impact toughness from 22.7 to 53.8 J/cm^(2).Additionally,under the same solution treatment,raising the aging temperature from 500 to 700℃ resulted in a decrease in the α_(s) phase content and a growth in the thickness of the α_(p) lamella and α_(s) phase.The impact toughness increased significantly with these changes.Samples with high α_(p) lamellae content or large α_(s) phase size exhibited high crack initiation and propagation energies.Impact deformation caused severe kinking of the α_(p) lamellae in crack initiation and propagation areas,leading to a uniform and high-density kernel average misorientation(KAM)distribu-tion,enhancing plastic deformation coordination and uniformity.Moreover,the multidirectional arrangement of coarserαcolonies and α_(p) lamellae continuously deflect the crack propagation direction,inhibiting crack propagation. 展开更多
关键词 novel titanium alloy multi-level lamellar microstructure impact toughness crack initiation and propagation
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A Multi-Level Semantic Constraint Approach for Highway Tunnel Scene Twin Modeling 被引量:2
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作者 LI Yufei XIE Yakun +3 位作者 CHEN Mingzhen ZHAO Yaoji TU Jiaxing HU Ya 《Journal of Geodesy and Geoinformation Science》 2025年第2期37-56,共20页
As a key node of modern transportation network,the informationization management of road tunnels is crucial to ensure the operation safety and traffic efficiency.However,the existing tunnel vehicle modeling methods ge... As a key node of modern transportation network,the informationization management of road tunnels is crucial to ensure the operation safety and traffic efficiency.However,the existing tunnel vehicle modeling methods generally have problems such as insufficient 3D scene description capability and low dynamic update efficiency,which are difficult to meet the demand of real-time accurate management.For this reason,this paper proposes a vehicle twin modeling method for road tunnels.This approach starts from the actual management needs,and supports multi-level dynamic modeling from vehicle type,size to color by constructing a vehicle model library that can be flexibly invoked;at the same time,semantic constraint rules with geometric layout,behavioral attributes,and spatial relationships are designed to ensure that the virtual model matches with the real model with a high degree of similarity;ultimately,the prototype system is constructed and the case region is selected for the case study,and the dynamic vehicle status in the tunnel is realized by integrating real-time monitoring data with semantic constraints for precise virtual-real mapping.Finally,the prototype system is constructed and case experiments are conducted in selected case areas,which are combined with real-time monitoring data to realize dynamic updating and three-dimensional visualization of vehicle states in tunnels.The experiments show that the proposed method can run smoothly with an average rendering efficiency of 17.70 ms while guaranteeing the modeling accuracy(composite similarity of 0.867),which significantly improves the real-time and intuitive tunnel management.The research results provide reliable technical support for intelligent operation and emergency response of road tunnels,and offer new ideas for digital twin modeling of complex scenes. 展开更多
关键词 highway tunnel twin modeling multi-level semantic constraints tunnel vehicles multidimensional modeling
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Research on Multi-Level Automatic Filling Optimization Design Method for Layered Cross-Sectional Layout of Umbilical 被引量:1
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作者 YIN Xu FAN Zhi-rui +4 位作者 CAO Dong-hui LIU Yu-jie LI Meng-shu YAN Jun YANG Zhi-xun 《China Ocean Engineering》 2025年第5期891-903,共13页
The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly comple... The umbilical,a key component in offshore energy extraction,plays a vital role in ensuring the stable operation of the entire production system.The extensive variety of cross-sectional components creates highly complex layout combinations.Furthermore,due to constraints in component quantity and geometry within the cross-sectional layout,filler bodies must be incorporated to maintain cross-section performance.Conventional design approaches based on manual experience suffer from inefficiency,high variability,and difficulties in quantification.This paper presents a multi-level automatic filling optimization design method for umbilical cross-sectional layouts to address these limitations.Initially,the research establishes a multi-objective optimization model that considers compactness,balance,and wear resistance of the cross-section,employing an enhanced genetic algorithm to achieve a near-optimal layout.Subsequently,the study implements an image processing-based vacancy detection technique to accurately identify cross-sectional gaps.To manage the variability and diversity of these vacant regions,the research introduces a multi-level filling method that strategically selects and places filler bodies of varying dimensions,overcoming the constraints of uniform-size fillers.Additionally,the method incorporates a hierarchical strategy that subdivides the complex cross-section into multiple layers,enabling layer-by-layer optimization and filling.This approach reduces manufac-turing equipment requirements while ensuring practical production process feasibility.The methodology is validated through a specific umbilical case study.The results demonstrate improvements in compactness,balance,and wear resistance compared with the initial cross-section,offering novel insights and valuable references for filler design in umbilical cross-sections. 展开更多
关键词 UMBILICAL cross-sectional layout multi-level filling layered layout optimization design
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A toughening strategy of the glass composite with a laminated interlocking feature
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作者 Qi WANG Li DING +6 位作者 Shuo WANG Danping RUAN Yuanzhi XU Yanshu CHU D.AROLA Bingbing AN Dongsheng ZHANG 《Applied Mathematics and Mechanics(English Edition)》 2025年第7期1315-1330,共16页
Inspired by brick-and-mortar architectures and suture interfaces,we propose a design of bioinspired nacre-like materials with interlocking sutures to improve the toughness of brittle materials.Laser-engraved glass int... Inspired by brick-and-mortar architectures and suture interfaces,we propose a design of bioinspired nacre-like materials with interlocking sutures to improve the toughness of brittle materials.Laser-engraved glass interlockers are laminated with soft interlayers in a staggered arrangement,and the fundamental mechanical properties of the structure are investigated through experiments and numerical modeling.It is found that the tensile performance,such as the strength and toughness,is strongly affected by the interlocking angle and suture line spacing.The geometric interlocking originated from suture interfaces as well as tablet sliding arising from the staggered arrangement of interlockers cooperatively contribute to enhancing the strength and toughness of this bioinspired design.Additionally,the finite element modeling shows the interfacial failure and plastic deformation,revealing the interplay of the geometric interlocking mechanism and the sliding mechanism.This novel bioinspired design paves a new path for fabrication of structural materials combining high stiffness,high strength,and enhanced toughness. 展开更多
关键词 jigsaw-like geometric interlocking nacre-like tablet sliding toughness GLASS
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Laser-Induced Nanowire Percolation Interlocking for Ultrarobust Soft Electronics
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作者 Yeongju Jung Kyung Rok Pyun +8 位作者 Sejong Yu Jiyong Ahn Jinsol Kim Jung Jae Park Min Jae Lee Byunghong Lee Daeyeon Won Junhyuk Bang Seung Hwan Ko 《Nano-Micro Letters》 2025年第6期40-54,共15页
Metallic nanowires have served as novel materials for soft electronics due to their outstanding mechanical compliance and electrical properties.However,weak adhesion and low mechanical robustness of nanowire networks ... Metallic nanowires have served as novel materials for soft electronics due to their outstanding mechanical compliance and electrical properties.However,weak adhesion and low mechanical robustness of nanowire networks to substrates significantly undermine their reliability,necessitating the use of an insulating protective layer,which greatly limits their utility.Herein,we present a versatile and generalized laser-based process that simultaneously achieves strong adhesion and mechanical robustness of nanowire networks on diverse substrates without the need for a protective layer.In this method,the laser-induced photothermal energy at the interface between the nanowire network and the substrate facilitates the interpenetration of the nanowire network and the polymer matrix,resulting in mechanical interlocking through percolation.This mechanism is broadly applicable across different metallic nanowires and thermoplastic substrates,significantly enhancing its universality in diverse applications.Thereby,we demonstrated the mechanical robustness of nanowires in reusable wearable physiological sensors on the skin without compromising the performance of the sensor.Furthermore,enhanced robustness and electrical conductivity by the laser-induced interlocking enables a stable functionalization of conducting polymers in a wet environment,broadening its application into various electrochemical devices. 展开更多
关键词 Nanowire percolation network Laser processing Mechanical interlocking FUNCTIONALIZATION Conducting polymer
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Multi-relation spatiotemporal graph residual network model with multi-level feature attention:A novel approach for landslide displacement prediction
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作者 Ziqian Wang Xiangwei Fang +3 位作者 Wengang Zhang Xuanming Ding Luqi Wang Chao Chen 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第7期4211-4226,共16页
Accurate prediction of landslide displacement is crucial for effective early warning of landslide disasters.While most existing prediction methods focus on time-series forecasting for individual monitoring points,ther... Accurate prediction of landslide displacement is crucial for effective early warning of landslide disasters.While most existing prediction methods focus on time-series forecasting for individual monitoring points,there is limited research on the spatiotemporal characteristics of landslide deformation.This paper proposes a novel Multi-Relation Spatiotemporal Graph Residual Network with Multi-Level Feature Attention(MFA-MRSTGRN)that effectively improves the prediction performance of landslide displacement through spatiotemporal fusion.This model integrates internal seepage factors as data feature enhancements with external triggering factors,allowing for accurate capture of the complex spatiotemporal characteristics of landslide displacement and the construction of a multi-source heterogeneous dataset.The MFA-MRSTGRN model incorporates dynamic graph theory and four key modules:multilevel feature attention,temporal-residual decomposition,spatial multi-relational graph convolution,and spatiotemporal fusion prediction.This comprehensive approach enables the efficient analyses of multi-source heterogeneous datasets,facilitating adaptive exploration of the evolving multi-relational,multi-dimensional spatiotemporal complexities in landslides.When applying this model to predict the displacement of the Liangshuijing landslide,we demonstrate that the MFA-MRSTGRN model surpasses traditional models,such as random forest(RF),long short-term memory(LSTM),and spatial temporal graph convolutional networks(ST-GCN)models in terms of various evaluation metrics including mean absolute error(MAE=1.27 mm),root mean square error(RMSE=1.49 mm),mean absolute percentage error(MAPE=0.026),and R-squared(R^(2)=0.88).Furthermore,feature ablation experiments indicate that incorporating internal seepage factors improves the predictive performance of landslide displacement models.This research provides an advanced and reliable method for landslide displacement prediction. 展开更多
关键词 Landslide displacement prediction Spatiotemporal fusion Dynamic graph Data feature enhancement multi-level feature attention
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Biomimetic Engineering High-Sensitivity Flexible Pressure Sensors with Ultra-Wide Pressure Detection Range via Synergistic Interlocked Structures and Multi-scale Micro-dome Interfaces
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作者 Junqiu Zhang Jiachao Wu +16 位作者 Lili Liu Tao Sun Xiangbo Gu Zijian Shi Xueyang Li Xueping Zhang Yu Chen Jiqi Gao Kejun Wang Bin Zhu Wenze Sun Yutao Mei Yubo Yan Yan Li Zhijing Wu Zhiwu Han Luquan Ren 《Journal of Bionic Engineering》 2025年第5期2550-2560,共11页
Flexible pressure sensors have excellent prospects in applications of human-machine interfaces,artificial intelligence and human health monitoring due to their bendable and lightweight characteristics compared to rigi... Flexible pressure sensors have excellent prospects in applications of human-machine interfaces,artificial intelligence and human health monitoring due to their bendable and lightweight characteristics compared to rigid pressure sensors.However,arising from the limited compressibility of soft materials and the hardening of microstructures at the device interface,there is always a trade-off between high sensitivity and broad sensing range for most flexible pressure sensors,which results in a gradual saturation response and limits their practical applications.Herein,inspired by the distinct pressure perception function of crocodile receptors,a highly sensitive and wide-range flexible pressure sensor with multiscale microdomes and interlocked architecture is developed via a facile PS-decorated molding method.Combined with interlocked architecture,the multiscale dome-shaped structured interface enhances the compressibility of the material through structural complementarity,increases the contact area between functional materials,which compensates for the stiffness induced by the deformation of dense microscale columns.This effectively mitigates structural hardening across a wide pressure range,leading to the overall high performance of the sensor.As a result,the obtained sensor exhibits a low detection limit of 5 Pa,a high sensitivity of 6.14 kPa^(-1),a wide measurement range up to 231 kPa,short response/recovery time of 56 ms/69 ms,outstanding stability over 10,000 cycles.Considering these excellent properties,the sensor shows promising potential in health monitoring,human-computer interaction,wearable electronics.This study presents a strategy for the fabrication of flexible pressure sensors exhibiting high sensitivity and a wide pressure response range. 展开更多
关键词 Biomimetic engineering Flexible pressure sensors Ultrahigh sensitivity and wide-range detection Multiscale interface interlocked structure
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A robust method for large-scale route optimization on lunar surface utilizing a multi-level map model
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作者 Yutong JIA Shengnan ZHANG +5 位作者 Bin LIU Kaichang DI Bin XIE Jing NAN Chenxu ZHAO Gang WAN 《Chinese Journal of Aeronautics》 2025年第3期134-150,共17页
As we look ahead to future lunar exploration missions, such as crewed lunar exploration and establishing lunar scientific research stations, the lunar rovers will need to cover vast distances. These distances could ra... As we look ahead to future lunar exploration missions, such as crewed lunar exploration and establishing lunar scientific research stations, the lunar rovers will need to cover vast distances. These distances could range from kilometers to tens of kilometers, and even hundreds and thousands of kilometers. Therefore, it is crucial to develop effective long-range path planning for lunar rovers to meet the demands of lunar patrol exploration. This paper presents a hierarchical map model path planning method that utilizes the existing high-resolution images, digital elevation models and mineral abundance maps. The objective is to address the issue of the construction of lunar rover travel costs in the absence of large-scale, high-resolution digital elevation models. This method models the reference and semantic layers using the middle- and low-resolution remote sensing data. The multi-scale obstacles on the lunar surface are extracted by combining the deep learning algorithm on the high-resolution image, and the obstacle avoidance layer is modeled. A two-stage exploratory path planning decision is employed for long-distance driving path planning on a global–local scale. The proposed method analyzes the long-distance accessibility of various areas of scientific significance, such as Rima Bode. A high-precision digital elevation model is created using stereo images to validate the method. Based on the findings, it can be observed that the entire route spans a distance of 930.32 km. The route demonstrates an impressive ability to avoid meter-level impact craters and linear structures while maintaining an average slope of less than 8°. This paper explores scientific research by traversing at least seven basalt units, uncovering the secrets of lunar volcanic activities, and establishing ‘golden spike’ reference points for lunar stratigraphy. The final result of path planning can serve as a valuable reference for the design, mission demonstration, and subsequent project implementation of the new manned lunar rover. 展开更多
关键词 Crewed lunar exploration Long-range path planningi multi-level map Deep learning Volcanic activities
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Multi-level distribution alignment-based domain adaptation for segmentation of 3D neuronal soma images
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作者 Li Ma Xuantai Xu Xiaoquan Yang 《Journal of Innovative Optical Health Sciences》 2025年第6期69-85,共17页
Deep learning networks are increasingly exploited in the field of neuronal soma segmentation.However,annotating dataset is also an expensive and time-consuming task.Unsupervised domain adaptation is an effective metho... Deep learning networks are increasingly exploited in the field of neuronal soma segmentation.However,annotating dataset is also an expensive and time-consuming task.Unsupervised domain adaptation is an effective method to mitigate the problem,which is able to learn an adaptive segmentation model by transferring knowledge from a rich-labeled source domain.In this paper,we propose a multi-level distribution alignment-based unsupervised domain adaptation network(MDA-Net)for segmentation of 3D neuronal soma images.Distribution alignment is performed in both feature space and output space.In the feature space,features from different scales are adaptively fused to enhance the feature extraction capability for small target somata and con-strained to be domain invariant by adversarial adaptation strategy.In the output space,local discrepancy maps that can reveal the spatial structures of somata are constructed on the predicted segmentation results.Then thedistribution alignment is performed on the local discrepancies maps across domains to obtain a superior discrepancy map in the target domain,achieving refined segmentation performance of neuronal somata.Additionally,after a period of distribution align-ment procedure,a portion of target samples with high confident pseudo-labels are selected as training data,which assist in learning a more adaptive segmentation network.We verified the superiority of the proposed algorithm by comparing several domain adaptation networks on two 3D mouse brain neuronal somata datasets and one macaque brain neuronal soma dataset. 展开更多
关键词 Unsupervised domain adaptation multi-level distribution alignment pseudo-labels 3D neuronal soma images
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MLRT-UNet:An Efficient Multi-Level Relation Transformer Based U-Net for Thyroid Nodule Segmentation
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作者 Kaku Haribabu Prasath R Praveen Joe IR 《Computer Modeling in Engineering & Sciences》 2025年第4期413-448,共36页
Thyroid nodules,a common disorder in the endocrine system,require accurate segmentation in ultrasound images for effective diagnosis and treatment.However,achieving precise segmentation remains a challenge due to vari... Thyroid nodules,a common disorder in the endocrine system,require accurate segmentation in ultrasound images for effective diagnosis and treatment.However,achieving precise segmentation remains a challenge due to various factors,including scattering noise,low contrast,and limited resolution in ultrasound images.Although existing segmentation models have made progress,they still suffer from several limitations,such as high error rates,low generalizability,overfitting,limited feature learning capability,etc.To address these challenges,this paper proposes a Multi-level Relation Transformer-based U-Net(MLRT-UNet)to improve thyroid nodule segmentation.The MLRTUNet leverages a novel Relation Transformer,which processes images at multiple scales,overcoming the limitations of traditional encoding methods.This transformer integrates both local and global features effectively through selfattention and cross-attention units,capturing intricate relationships within the data.The approach also introduces a Co-operative Transformer Fusion(CTF)module to combine multi-scale features from different encoding layers,enhancing the model’s ability to capture complex patterns in the data.Furthermore,the Relation Transformer block enhances long-distance dependencies during the decoding process,improving segmentation accuracy.Experimental results showthat the MLRT-UNet achieves high segmentation accuracy,reaching 98.2% on the Digital Database Thyroid Image(DDT)dataset,97.8% on the Thyroid Nodule 3493(TG3K)dataset,and 98.2% on the Thyroid Nodule3K(TN3K)dataset.These findings demonstrate that the proposed method significantly enhances the accuracy of thyroid nodule segmentation,addressing the limitations of existing models. 展开更多
关键词 Thyroid nodules endocrine system multi-level relation transformer U-Net self-attention external attention co-operative transformer fusion thyroid nodules segmentation
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3维可视化安全联锁系统研制及应用
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作者 金志伟 景川 +1 位作者 邢盼 蒋文静 《兵工自动化》 北大核心 2026年第2期37-39,60,共4页
针对2.4 m跨声速风洞运行监控缺少统一的基础显示平台,无法全面、准确、集中监测风洞整体运行情况,提出基于数字化技术研制3维可视化安全联锁监控系统。将风洞洞体、流场及主要执行机构等的总体态势以3维视图方式进行呈现,对油源、气密... 针对2.4 m跨声速风洞运行监控缺少统一的基础显示平台,无法全面、准确、集中监测风洞整体运行情况,提出基于数字化技术研制3维可视化安全联锁监控系统。将风洞洞体、流场及主要执行机构等的总体态势以3维视图方式进行呈现,对油源、气密封、电源等系统的状态进行远程在线监控。在控制系统出现故障、设备状态超出安全范围、模型出现剧烈抖动等情况时,及时对整个风洞系统实施联锁保护,同时解决风洞运行过程中监控内容过于繁杂及分散等问题,并优化完善设备故障的告警功能。结果表明:该系统在投入2.4 m跨声速风洞日常应用时,能够满足风洞运行的安全监控要求,使用效果良好。 展开更多
关键词 风洞 监控 3维可视化 安全联锁系统
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连锁董事网络会提升企业ESG绩效吗?
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作者 吕英 谷晓雪 《首都经济贸易大学学报》 北大核心 2026年第1期102-114,共13页
为响应国家“双碳”目标和可持续发展的要求,ESG绩效的提升已成为企业经营和发展的重要任务。为深入了解企业ESG绩效的驱动因素,本文基于资源依赖理论和社会网络理论,以2009—2023年沪深A股上市公司为研究样本,实证分析连锁董事网络对企... 为响应国家“双碳”目标和可持续发展的要求,ESG绩效的提升已成为企业经营和发展的重要任务。为深入了解企业ESG绩效的驱动因素,本文基于资源依赖理论和社会网络理论,以2009—2023年沪深A股上市公司为研究样本,实证分析连锁董事网络对企业ESG绩效的影响路径。研究结果表明:(1)连锁董事网络能够改善企业ESG绩效,该研究结论在控制内生性及进行一系列稳健性检验后依然成立;(2)连锁董事网络通过资源溢出、协同和监督效应直接促进企业ESG绩效的提升;(3)在间接影响路径中,开放式创新构成连锁董事网络影响企业ESG绩效的机制变量;(4)公司治理和媒体关注程度均能加强连锁董事网络对企业ESG绩效的提升作用;(5)异质性分析显示,在所处行业集中度较高的企业和非国有企业中,连锁董事网络对企业ESG绩效的促进效果更明显。研究结论为加强连锁董事网络的综合治理效应以及提升企业ESG绩效提供了重要参考。 展开更多
关键词 连锁董事网络 企业ESG绩效 开放式创新 资源溢出 协同效应 监督效应
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穴位贴敷联合微创交锁髓内钉内固定术治疗胫腓骨骨折的效果
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作者 王明绪 李南 《临床医学研究与实践》 2026年第3期125-128,共4页
目的探讨穴位贴敷联合微创交锁髓内钉内固定术治疗胫腓骨骨折的效果。方法选择2021年1月5日至2024年7月3日连云港市赣榆区人民医院收治的88例胫腓骨骨折患者为研究对象,随机将其分为对照组(微创交锁髓内钉内固定术)与观察组(穴位贴敷联... 目的探讨穴位贴敷联合微创交锁髓内钉内固定术治疗胫腓骨骨折的效果。方法选择2021年1月5日至2024年7月3日连云港市赣榆区人民医院收治的88例胫腓骨骨折患者为研究对象,随机将其分为对照组(微创交锁髓内钉内固定术)与观察组(穴位贴敷联合微创交锁髓内钉内固定术),各44例。对比两组的治疗效果。结果观察组的治疗显效率高于对照组(P<0.05)。观察组术后1个月的肿瘤坏死因子-α(TNF-α)、白细胞介素-1(IL-1)、白细胞介素-6(IL-6)水平及全血高切黏度、全血低切黏度、血浆黏度明显低于对照组(P<0.05)。术后1、2、3个月,观察组的口述描绘评分法(VRS)评分明显低于对照组(P<0.05)。术后3个月,观察组的骨碱性磷酸酶(BALP)、骨钙素(BGP)水平明显高于对照组(P<0.05)。观察组的并发症总发生率为2.27%,较对照组的18.18%更低(P<0.05)。结论穴位贴敷联合微创交锁髓内钉内固定术治疗胫腓骨骨折效果显著,可降低患者的疼痛程度及并发症发生率,改善机体的炎症反应、血流动力学及骨代谢水平。 展开更多
关键词 穴位贴敷 微创交锁髓内钉内固定术 胫腓骨骨折 炎症反应 血流动力学
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Interlock可解脱弹簧圈在脾动脉瘤腔内治疗中的应用 被引量:3
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作者 张省 范毓 +5 位作者 秦金保 李维敏 殷敏毅 叶开创 杨心蕊 陆信武 《现代生物医学进展》 CAS 2020年第11期2059-2063,共5页
目的:探究Interlock可解脱弹簧圈在脾动脉瘤的腔内治疗中的应用价值。方法:回顾性分析2016年2月至2019年2月于本中心使用Interlock可解脱弹簧圈治疗的36例脾动脉瘤患者的临床资料,包括10例男性,26例女性,31例真性动脉瘤,5例假性脾动脉瘤... 目的:探究Interlock可解脱弹簧圈在脾动脉瘤的腔内治疗中的应用价值。方法:回顾性分析2016年2月至2019年2月于本中心使用Interlock可解脱弹簧圈治疗的36例脾动脉瘤患者的临床资料,包括10例男性,26例女性,31例真性动脉瘤,5例假性脾动脉瘤,术前均行超声或CTA明确诊断。术中栓塞后,立即血管造影以明确技术成功率。围手术期及术后2周、3个月和6个月监测血常规、胰淀粉酶和主动脉CTA,观察并发症的发生情况。结果:6例患者弹簧圈栓塞动脉瘤远近端及瘤腔,其余仅栓塞脾动脉瘤瘤腔。术中DSA血管造影提示即刻脾动脉瘤栓塞闭塞率为97%以上,术中共使用128枚Interlock弹簧圈,其中104枚为钻石型,24枚为普通2D型。弹簧圈平均直径为6.3±4.2(2-12)mm,平均长度为16±13.5(3-32)mm,瘤体平均尺寸为40.6±12.5(15-70)mm。围手术期无并发症发生。平均随访10.0±3.2(6-15)个月,1月后2例出现脾梗死,7例发生轻微腹痛及低热等症状,所有病例均未见瘤腔再通和瘤体增大。结论:Interlock可解脱弹簧圈可以安全有效地治疗脾动脉瘤,但其远期疗效需长期随访观察。 展开更多
关键词 脾动脉瘤 interlock可解脱弹簧圈 栓塞 腔内治疗
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锁结式口腔矫治器与颌架定位式口腔矫治器在阻塞性睡眠呼吸暂停低通气综合征颞下颌关节矫正中的应用
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作者 张玺 刘璐玮 倪密 《临床和实验医学杂志》 2026年第1期93-97,共5页
目的比较分析锁合型与颌位定位型口腔矫治装置对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并颞颌关节紊乱病(TMD)患者的临床干预价值。方法前瞻性选取2022年1月至2024年12月南京医科大学附属南京医院(南京市第一医院)收治的80例中度OSAH... 目的比较分析锁合型与颌位定位型口腔矫治装置对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并颞颌关节紊乱病(TMD)患者的临床干预价值。方法前瞻性选取2022年1月至2024年12月南京医科大学附属南京医院(南京市第一医院)收治的80例中度OSAHS合并TMD患者,按照随机数字表法将其分为对照组和干预组,每组各40例。对照组使用颌架定位式口腔矫治器,干预组使用锁结式口腔矫治器,均持续干预12周。治疗前、治疗12周后,比较两组多导睡眠监测核心参数[呼吸暂停低通气指数(AHI)、睡眠效率、最低血氧饱和度]、颞颌关节功能分级指标(Fricton指数)、Epworth嗜睡量表(ESS)与Berlin睡眠症状调查问卷(BSSQ)评分及睡眠呼吸暂停的生活质量指数(SAQLI)变化。结果治疗12周后,两组患者的AHI均较治疗前降低,睡眠效率、最低血氧饱和度均较治疗前升高,差异均有统计学意义(P<0.05),而两组患者平均血氧饱和度、平均心率、最大心率与治疗前比较,差异均无统计学意义(P>0.05);治疗12周后,两组患者的各项睡眠呼吸参数比较,差异均无统计学意义(P>0.05)。治疗12周后,两组的ESS评分、BSSQ评分均较治疗前降低,差异均有统计学意义(P<0.05),但组间比较差异均无统计学意义(P>0.05)。治疗12周后,两组患者的生活质量各维度评分及总分均较治疗前升高,差异均有统计学意义(P<0.05),但组间比较差异均无统计学意义(P>0.05)。结论两种口腔矫治技术在改善OSAHS合并TMD患者的呼吸事件、睡眠质量及生活质量方面具有相近的临床疗效及安全性,其治疗参数优化可依据个体颌骨解剖特征进行临床决策。 展开更多
关键词 阻塞性睡眠呼吸暂停综合征 锁结式口腔矫治器 颌架定位式口腔矫治器 颞下颌关节紊乱 睡眠呼吸 生活质量
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Preparation of ultra-fine grain Ni-Al-WC coating with interlocking bonding on austenitic stainless steel by laser clad and friction stir processing 被引量:4
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作者 熊拥军 邱子力 +3 位作者 李瑞迪 袁铁锤 吴宏 刘锦辉 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2015年第11期3685-3693,共9页
The ultra-fine structured Ni?Al?WC layer with interlocking bonding was fabricated on austenitic stainless steel by combination of laser clad and friction stir processing (FSP). Laser was initially applied to Ni?Al ele... The ultra-fine structured Ni?Al?WC layer with interlocking bonding was fabricated on austenitic stainless steel by combination of laser clad and friction stir processing (FSP). Laser was initially applied to Ni?Al elemental powder preplaced on the austenitic stainless steel substrate to produce a coating for further processing. The as-received coating was subjected to FSP treatment, processed by a rotary tool rod made of WC?Co alloy, to obtain sample for inspection. Microstructure, phase constitutions, hardness and wear property were investigated by methods of scanning electronic microscopy (SEM) with energy-dispersive X-ray spectroscopy (EDX) microanalysis, and X-ray diffraction (XRD), hardness test alongside with dry sliding wear test. The results show that the severe deformation effect exerted on the specimen resulted in an ultra-fine grain layer of about 100μmin thickness and grain size of 1?2μm. Synergy between introduction of WC particles to the deformation layer and deformation strengthening contributes greatly to the increase in hardness and friction resistance. An interlocking bonding between the coating and matrix which significantly improves bonding strength was formed due to the severe deformation effect. 展开更多
关键词 laser clad friction stir processing Ni-Al-WC coating ultra-fine grain interlocking bonding
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软土夹层地基上的互锁式L型沉箱稳定性试验研究
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作者 陈树理 郭伟 +1 位作者 任宇晓 陈伟 《岩土力学》 北大核心 2026年第1期49-60,共12页
互锁式L型沉箱作为一种新型沉箱结构,能够有效应对复杂海洋环境荷载。该结构在深水港码头、防波堤和人工岛等海洋基础设施中具有广阔的应用前景。通过室内加载模型试验,探究了所提出的互锁式L型沉箱(interlocking L-shaped caisson,简称... 互锁式L型沉箱作为一种新型沉箱结构,能够有效应对复杂海洋环境荷载。该结构在深水港码头、防波堤和人工岛等海洋基础设施中具有广阔的应用前景。通过室内加载模型试验,探究了所提出的互锁式L型沉箱(interlocking L-shaped caisson,简称ILC)替代传统L型沉箱(conventional L-shaped caisson,简称CLC)的可行性。研究了相邻ILC形成的六棱柱空腔内部的填充材料、地基类型和荷载形式对沉箱码头稳定性的影响。与CLC码头相比,在条形荷载下采用碎石或混凝土块联锁加固的ILC码头极限承载力分别提高了15.5%和20.1%。混凝土块联锁加固的ILC码头具有更优的承载性能。随着软土夹层地基替代砂土地基,ILC码头的极限承载力降低,其破坏模式由倾覆破坏变为整体失稳破坏,破坏面形态由直线-圆弧状变为多折线状。随着作用范围更小的集中荷载替代条形荷载,ILC码头的整体性变差,极限承载力显著降低,沉箱附近回填土表面沉降增大。 展开更多
关键词 海洋基础设施 互锁式L型沉箱 软土夹层地基 模型试验 稳定性
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Multi-level access control model for tree-like hierarchical organizations
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作者 於光灿 李瑞轩 +3 位作者 卢正鼎 Mudar Sarem 宋伟 苏永红 《Journal of Southeast University(English Edition)》 EI CAS 2008年第3期393-396,共4页
An access control model is proposed based on the famous Bell-LaPadula (BLP) model.In the proposed model,hierarchical relationships among departments are built,a new concept named post is proposed,and assigning secur... An access control model is proposed based on the famous Bell-LaPadula (BLP) model.In the proposed model,hierarchical relationships among departments are built,a new concept named post is proposed,and assigning security tags to subjects and objects is greatly simplified.The interoperation among different departments is implemented through assigning multiple security tags to one post, and the more departments are closed on the organization tree,the more secret objects can be exchanged by the staff of the departments.The access control matrices of the department,post and staff are defined.By using the three access control matrices,a multi granularity and flexible discretionary access control policy is implemented.The outstanding merit of the BLP model is inherited,and the new model can guarantee that all the information flow is under control.Finally,our study shows that compared to the BLP model,the proposed model is more flexible. 展开更多
关键词 multi-level access control hierarchical organization multiple security tags
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临海钢厂水电共生海水淡化系统的安全控制策略研究
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作者 吴礼云 郑忠 +3 位作者 陈素君 于悦波 陈德磊 张开天 《重庆大学学报》 北大核心 2026年第2期19-33,共15页
以临海钢铁企业的水电共生海水淡化新技术系统为对象,针对该系统以汽轮机乏汽作为低温多效蒸发海水淡化的热源,汽轮发电机组与海水淡化机组耦合紧密,联合安全控制难度大、技术缺乏的问题,从优先考虑设备安全运行的角度,设计了适合水电... 以临海钢铁企业的水电共生海水淡化新技术系统为对象,针对该系统以汽轮机乏汽作为低温多效蒸发海水淡化的热源,汽轮发电机组与海水淡化机组耦合紧密,联合安全控制难度大、技术缺乏的问题,从优先考虑设备安全运行的角度,设计了适合水电共生工艺的启动逻辑、设备故障下的设备安全联锁保护逻辑、汽轮机低负荷场景下海水淡化装置的模式切换保护逻辑等安全控制策略,可实施对汽轮发电机组和海水淡化装置的双向联锁保护。该技术方案在某沿海钢铁厂的实际运用结果表明,所设计的水电共生安全控制策略,可实现整个系统的安全有序启动;在设备故障场景下能够实现主设备系统的双向安全联锁停机,具备既可在汽轮发电机组故障时连停海水淡化装置,也可以在海水淡化装置故障时连停汽轮发电机组;同时,安全策略能适应钢厂煤气大负荷调节的需要,安全运行效果明显。 展开更多
关键词 临海钢厂 水电共生 海水淡化 联锁保护 启停逻辑 大负荷调节
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