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Reform of Teacher-Machine-Student Interactive Teaching Model of“HarmonyOS Development Technology”Course Based on Congyou Platform
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作者 Yixian Liu Jun Guo +1 位作者 Dongming Chen Zhiliang Zhu 《计算机教育》 2026年第3期158-166,共9页
Aiming at the problems of lagging curriculum,weak practice,and single evaluation in the cultivation of HarmonyOS Development talents,this study constructs a“teacher-machine-student”ternary interactive teaching model... Aiming at the problems of lagging curriculum,weak practice,and single evaluation in the cultivation of HarmonyOS Development talents,this study constructs a“teacher-machine-student”ternary interactive teaching model based on the Congyou platform.Through the building block curriculum system,the HarmonyOS technology stack is decoupled into dynamic capability units,and a multi-disciplinary cross-case library is jointly built with Huawei,which significantly improves the synchronization of teaching content and industrial technology.This paper innovatively designs an AI collaborative teaching system,which employs knowledge graphs to plan learning paths,utilizes virtual equipment clusters to simulate development environments,and establishes a“diagnosis-feedback-enhancement”closed loop through AI-based review,thereby effectively improving students’development efficiency and code reuse rate.A three-dimensional evaluation model integrating task outcomes,process performance,and innovation is constructed,incorporating indicators such as code standardization and an innovation index to strengthen the cultivation of engineering thinking and innovative ability.Furthermore,a data-driven support platform is built to generate student competency profiles,open up the“credit-competency-certification”pathway,promote the transformation of course achievements into contributions to the Huawei ecosystem,and significantly shorten the job adaptation cycle for graduates.The research results provide a replicable paradigm for the cultivation of domestic operating system talents. 展开更多
关键词 interactive teaching model HarmonyOS development technology Building-block curriculum system Domestic software ecosystem
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A review of microfluidic technology for CO_(2)sequestration in saline aquifers
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作者 Yiyan Zhong Qi Li +2 位作者 Wenbin Gao Yiping Wen Yao Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期810-829,共20页
In recent years,microfluidic technology has emerged as a powerful and innovative tool,attracting significant attention for its ability to provide real-time visualization of CO_(2)flow,mass transfer,and reaction proces... In recent years,microfluidic technology has emerged as a powerful and innovative tool,attracting significant attention for its ability to provide real-time visualization of CO_(2)flow,mass transfer,and reaction processes in porous media.This review examines the application of microfluidic technology in CO_(2)sequestration in saline aquifers,emphasizing the advantages of saline aquifer for geological sequestration,including safety,high storage capacity,stability,and cost-effectiveness.The materials used for microfluidic chips and the design of microchannels are systematically reviewed,offering forward-looking recommendations for chip selection and microchannel characterization in future research on CO_(2)sequestration in saline aquifer.Based on a detailed analysis of advancements in microfluidic technology,this review highlights key findings related to CO_(2)trapping mechanisms,salt precipitation,and CO_(2)-water-rock chemical interactions within saline aquifers.Although microfluidic technology shows great promise in these areas,this review identifies limitations in current studies and outlines future research directions,aiming to promote further innovation and broader application of microfluidic technology in the field of CO_(2)sequestration in saline aquifer. 展开更多
关键词 Microfluidic technology Chip materials Microchannel fabrication CO_(2)trapping mechanisms Salt precipitation CO_(2)-water-rock interaction
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Research on the process of fabricating a multi-layer metal micro-structure based on UV-LIGA overlay technology 被引量:3
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作者 Yali Ma Wenkai Liu Chong Liu 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2019年第2期83-88,共6页
In this paper,we report the study of the process of fabricating a multi-layermetal micro-structure using UV-LIGA overlay technology,includingmask fabrication,substrate treatment,and UV-LIGA overlay processes.To solve ... In this paper,we report the study of the process of fabricating a multi-layermetal micro-structure using UV-LIGA overlay technology,includingmask fabrication,substrate treatment,and UV-LIGA overlay processes.To solve the process problems in the masking procedure,the swelling problemof the first layer of SU-8 thick photoresist was studied experimentally.The 5μmline-width compensation and closed 20μmand 30μmisolation strips were designed and fabricated around the micro-structure pattern.The pore problemin the Ni micro-electroforming layer was analyzed and the electroforming parameters were improved.The pH value of the electroforming solution should be controlled between 3.8 and 4.4 and the current density should be below 3 A/dm^2.To solve the problems of high inner stress and incomplete development of the micro-cylinder hole array with a diameter of 30μm,the lithography process was optimized.The pre-baking temperature was increased via gradient heating and rose every 5℃ from 65℃ to 85℃ and then remained at 85℃ for 50 min–1 h.In addition,the full contact exposure was used.Finally,a multi-layer metal micro-structure with high precision and good quality of microelectroforming layer was fabricated using UV-LIGA overlay technology. 展开更多
关键词 UV-LIGA OVERLAY technology SU-8 photoresist Micro-electroforming technology multi-layer METAL MICRO-STRUCTURE
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Research on the Multi-Interactive Intelligent Teaching Model of College English in the Information Technology Environment
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作者 MA Huan 《International English Education Research》 2019年第3期43-45,共3页
The multi-interactive teaching mode based on the information technology is a new teaching mode, which promotes students' autonomous learning and research-oriented learning through the online and offline effective ... The multi-interactive teaching mode based on the information technology is a new teaching mode, which promotes students' autonomous learning and research-oriented learning through the online and offline effective interaction in and out of class, fully embodying the principle of the learning-orientation. Based on this, this paper focuses on the connotation and the theoretical basis o f the multi-interactive teaching model, as well as its implementation practices and characteristics, with a view o f providing help to improve the quality of the college English teaching. 展开更多
关键词 Information technology environment COLLEGE ENGLISH multiple interaction intelligent TEACHING mode RESEARCH
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Network Interactive Teaching in High School Information Technology Classroom
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作者 MAOQili 《外文科技期刊数据库(文摘版)教育科学》 2022年第1期075-078,共4页
Network interactive teaching is an advanced teaching idea. Under the background of the continuous development of information technology, the teaching content and information technology are combined to achieve the seam... Network interactive teaching is an advanced teaching idea. Under the background of the continuous development of information technology, the teaching content and information technology are combined to achieve the seamless connection of teaching links such as "speaking, thinking, practice and application" in teaching activities. Information technology as a technical course, its teaching focus is to improve students' ability to use information technology. Therefore, in the process of continuous development and improvement of classroom interactive network teaching, senior high school information technology teachers should carry out the teaching idea of "student-centered", give play to the student-centered status, so as to improve the quality of classroom teaching. Due to the particularity and natural advantages of the subject, information technology can conveniently realize the development of interactive teaching mode based on network in the classroom. This paper mainly discusses the practice and exploration of network interactive teaching in high school information technology classroom and its application effect analysis. 展开更多
关键词 high school information technology classroom NETWORK interactive teaching
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Strengthening the three-dimensional comprehensive observation system of multi-layer interaction on the Tibetan Plateau to cope with the warming and wetting trend 被引量:1
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作者 Yaoming Ma Binbin Wang +5 位作者 Xuelong Chen Lei Zhong Zeyong Hu Weiqiang Ma Cunbo Han Maoshan Li 《Atmospheric and Oceanic Science Letters》 CSCD 2022年第4期67-71,共5页
Changes in the water cycle on the Tibetan Plateau(TP)have a significant impact on local agricultural production and livelihoods and its downstream regions.Against the background of widely reported warming and wetting,... Changes in the water cycle on the Tibetan Plateau(TP)have a significant impact on local agricultural production and livelihoods and its downstream regions.Against the background of widely reported warming and wetting,the hydrological cycle has accelerated and the likelihood of extreme weather events and natural disasters occurring(i.e.,snowstorms,floods,landslides,mudslides,and ice avalanches)has also intensified,especially in the highelevation mountainous regions.Thus,an accurate estimation of the intensity and variation of each component of the water cycle is an urgent scientific question for the assessment of plateau environmental changes.Following the transformation and movement of water between the atmosphere,biosphere and hydrosphere,the authors highlight the urgent need to strengthen the three-dimensional comprehensive observation system(including the eddy covariance system;planetary boundary layer tower;profile measurements of temperature,humidity,and wind by microwave radiometers,wind profiler,and radiosonde system;and cloud and precipitation radars)in the TP region and propose a practical implementation plan.The construction of such a three-dimensional observation system is expected to promote the study of environmental changes and natural hazards prevention. 展开更多
关键词 Plateau warming and wetting Hydrological cycle Three-dimensional comprehensive observation system of multi-layer interaction Mountain-disaster response Tibetan Plateau
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Interaction mechanisms between green development and low-carbon economy in China:Using digital intelligence technologies as a coupling point
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作者 DU Yang XU Jun +1 位作者 YUAN Xiao YANG Qing-qing 《Ecological Economy》 2025年第1期81-99,共19页
Green development and the low-carbon economy in China have operated as parallel,distinct systems,with interactions limited to energy,industry,and technology.Guided by the concept of high-quality growth,green developm... Green development and the low-carbon economy in China have operated as parallel,distinct systems,with interactions limited to energy,industry,and technology.Guided by the concept of high-quality growth,green development—centered on sustainability principles and green targets—has focused on green living,production,industrial optimization,system-building,land-use planning,and global ecological objectives,thereby forming a uniquely Chinese green development framework.Similarly,the low-carbon economy,structured around carbon emission goals,development drivers,models of growth,management mechanisms,and international carbon responsibilities,has also developed a distinct framework.Introducing digital intelligence as a new dimension can serve as a coupling point to foster interactive mechanisms between green development and the low-carbon economy.These interactive mechanisms are reflected through smart green cloud collaboration systems and intelligent low-carbon governance platforms,using digital intelligence technology to enhance the synergy between green and low-carbon efforts in energy,carbon management,technology,innovation,governance,and the economy.Through analyzing these mechanisms,and returning to sustainability principles while responding to China's modern development philosophy,a uniquely Chinese theory and framework for green and low-carbon development can be constructed. 展开更多
关键词 green development low-carbon economy digital intelligence technology interactION
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Advances in applying somatosensory interaction technology in geriatric care:A bibliometric analysis
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作者 Changle Pei Weibo Lyu +4 位作者 Jingxia Liu Yan Wang Wenjia Ye Zhou Zhou Kangyao Cheng 《International Journal of Nursing Sciences》 CSCD 2024年第5期571-577,I0003,I0004,共9页
Objectives:Somatosensory Interaction Technology(SIT)is used in various aspects of geriatric care.We aimed to conduct a bibliometric analysis to summarize relevant publications and visualize publication characteristics... Objectives:Somatosensory Interaction Technology(SIT)is used in various aspects of geriatric care.We aimed to conduct a bibliometric analysis to summarize relevant publications and visualize publication characteristics,current hotspots,and development trends,thereby inspiring subsequent researches.Methods:We searched theWeb of Science Core Collection database for publications on the application of SIT in geriatric care.Bibliometric visualization and clustering analysis were performed using VOSviewer V1.6.18 Software,while keywords burst detection analysis was conducted with CiteSpace 6.1.R6 Software.Results:After screening,a total of 1,019 publications were included.The number of publications on SIT in geriatric care is gradually increasing,exhibiting a rapid growth rate.The United States,Canada,and Australia led in terms of publication volume.Keyword clustering analysis identified major research hotspots:crisis warning,somatic abilities,rehabilitation training and psychosocial support.Initial studies primarily explored themes such as recovery,movement,systems,and later shifted towards gait analysis,muscle strength,parameters,and home-based care.More recently,research themes have evolved to dementia,machine learning,and gamification.Conclusions:SIT is innovative for promoting active aging,advancing intelligent healthcare,and elevating the daily quality of life for older adults in clinical and domestic settings.Applications of SIT can be categorized into early warning systems for crises,detailed analyses of physical conditions,rehabilitation enhancement,and support for psychosocial health.Research trends have transitioned from whole-body recognition to precise feedback,from a focus on physical health to mental health,and from technical feasibility to user-friendliness.Future research should focus on developing accessible and user-friendly devices,fostering interdisciplinary collaborations for innovation,expanding research to address both the physical and mental health needs of diverse older adults,and integrating emerging technologies to enhance data precision and accelerate the development of intelligent platforms. 展开更多
关键词 BIBLIOMETRICS Data visualization Geriatric care Health management REVIEW Somatosensory interaction technology
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The Using Condition of Interactive Reading Strategy in Reading Scientific and Technological English Literature of Postgraduates of Engineering
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作者 苏红 CUI Xiao-ling 《海外英语》 2014年第15期89-91,共3页
In the reading process and after reading of the scientific and technological English literature for postgraduates of engineering, there are several barriers like the understanding of the vocabulary, the analyzing the ... In the reading process and after reading of the scientific and technological English literature for postgraduates of engineering, there are several barriers like the understanding of the vocabulary, the analyzing the complex sentences and the grasping the whole texts. This paper tries to investigate the using condition of interactive reading strategy in reading scientific and technological English literature of postgraduates of engineering. The study reveals that postgraduates of engineering frequently using some of strategies of the interactive reading strategy, but the overall using condition is only in the average level, and is not so flexible. 展开更多
关键词 interactive READING STRATEGY SCIENTIFIC and techno
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Convective transport of nanoparticles in multi-layer fluid flow 被引量:4
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作者 K.VAJRAVELU K.V.PRASAD S.ABBASBANDY 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2013年第2期177-188,共12页
Technologically, multi-layer fluid models are important in understanding fluid-fluid or fluid-nanoparticle interactions and their effects on flow and heat transfer characteristics. However, to the best of the authors... Technologically, multi-layer fluid models are important in understanding fluid-fluid or fluid-nanoparticle interactions and their effects on flow and heat transfer characteristics. However, to the best of the authors' knowledge, little attention has been paid to the study of three-layer fluid models with nanofluids. Therefore, a three-layer fluid flow model with nanofluids is formulated in this paper. The governing coupled nonlinear differential equations of the problem are non-dimensionalized by using appropriate fundamental quantities. The resulting multi-point boundary value problem is solved numerically by quasi-linearization and Richardson's extrapolation with modified boundary conditions. The effects of the model parameters on the flow and heat transfer are obtained and analyzed. The results show that an increase in the nanoparticle concentration in the base fluid can modify the fluid-velocity at the interface of the two fluids and reduce the shear not only at the surface of the clear fluid but also at the interface between them. That is, nanofluids play a vital role in modifying the flow phenomena. Therefore, one can use nanofluids to obtain the desired qualities for the multi-fluid flow and heat transfer characteristics. 展开更多
关键词 multi-layer fluid model interactION NANOFLUID
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A Study of Multi-Permeating TiN/Ti Alloying Layer Using Plasma Surface Alloying Technology
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作者 刘燕萍 徐晋勇 +6 位作者 隗小云 王建忠 高原 徐重 张广秋 葛袁静 张跃飞 《Plasma Science and Technology》 SCIE EI CAS CSCD 2006年第2期213-216,共4页
TiN/Ti multi-permeating alloying layer has been formed on the low carbon steel by means of the double glow-discharge plasma surface alloying technique and hollow-cathode effect. The alloying layer was detected by axio... TiN/Ti multi-permeating alloying layer has been formed on the low carbon steel by means of the double glow-discharge plasma surface alloying technique and hollow-cathode effect. The alloying layer was detected by axiovert 25 CA optical microscope with computer analyzing software (LEC), GDA-2 glow discharge spectroscopy (GDS), X-ray diffraction (XRD) and galvanochemical method. The results showed that the thickness of TiN/Ti multi-permeating alloying layer was about 10μm, the content of Ti on the surface was up to 63.48 wt% and the content of N was up to 12.46 wt%. The atom Ti and N concentrations changed gradually across the depth of the alloying layer and the preferred orientation of TiN/Ti alloying layer was crystal surface (200). The multi-permeating alloying layer and substrate were combined through metallurgy. The surface appearances of the multi-permeating alloying layer were uniform and of a compact cellular structure. The hardness of the surface was about 1600-3000 HV0.1. The corrosion resistance of the permeating TiN/Ti alloying layer in 0.5 mol/L H2SO4 solution was greatly increased and the corrosion rate was only 0.3082 g/m^2. h. 展开更多
关键词 plasma surface technology TiN multi-layer double glow discharge process diffusion structure corrosion resistance
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An Overview of Interactive Immersive Services
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作者 Xiaozhi Yuan Qingyang Wang +5 位作者 Linfeng Zhang Li Peng Xiaojie Zhu Jinlan Ma Zhan Liu Yuxiang Jiang 《China Communications》 SCIE CSCD 2023年第12期1-18,共18页
Immersive services are the typical emerging services in current IMT-2020 network.With the development of network evolution,real-time interactive applications emerge one after another.This article provides an overview ... Immersive services are the typical emerging services in current IMT-2020 network.With the development of network evolution,real-time interactive applications emerge one after another.This article provides an overview on immersive services which focus on real-time interaction.The scenarios,framework,requirements,key technologies,and issues of interactive immersive service are presented. 展开更多
关键词 framework interactive immersive service key technology REQUIREMENT SCENARIO
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Multi-layer phenomena in petawatt laser-driven acceleration of heavy ions
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作者 苏琬晴 曹喜光 +2 位作者 马春旺 王玉廷 张国强 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第2期70-76,共7页
Laser-accelerated high-flux-intensity heavy-ion beams are important for new types of accelerators.A particle-in-cell program(Smilei) is employed to simulate the entire process of Station of Extreme Light(SEL) 100 PW l... Laser-accelerated high-flux-intensity heavy-ion beams are important for new types of accelerators.A particle-in-cell program(Smilei) is employed to simulate the entire process of Station of Extreme Light(SEL) 100 PW laser-accelerated heavy particles using different nanoscale short targets with a thickness of 100 nm Cr, Fe, Ag, Ta, Au, Pb, Th and U, as well as 200 nm thick Al and Ca. An obvious stratification is observed in the simulation. The layering phenomenon is a hybrid acceleration mechanism reflecting target normal sheath acceleration and radiation pressure acceleration, and this phenomenon is understood from the simulated energy spectrum,ionization and spatial electric field distribution. According to the stratification, it is suggested that high-quality heavy-ion beams could be expected for fusion reactions to synthesize superheavy nuclei. Two plasma clusters in the stratification are observed simultaneously, which suggest new techniques for plasma experiments as well as thinner metal targets in the precision machining process. 展开更多
关键词 petawatt laser-plasma interaction laser-driven heavy-ion accelerator for synthesizing superheavy nuclei PARTICLE-IN-CELL multi-layer phenomena target fabrication
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3D Seismic Technology Applications to the Analysis of Sedimentary Basins
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作者 Xiangquan Li Tao Jiang 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期202-202,共1页
The recent advances of 3D seismic technique applied in geological study of sedimentary basin analysis were reviewed.The achievements in the study of the sedimentology,structural analysis,fluid-rock interaction and ign... The recent advances of 3D seismic technique applied in geological study of sedimentary basin analysis were reviewed.The achievements in the study of the sedimentology,structural analysis,fluid-rock interaction and igneous geology were summarized.Because 3D seismic resolution and interpretation technology are enhanced surprisingly. 展开更多
关键词 3D seismic technology basin analysis fluid-rock interactions seismic stratigraphy structural analysis igneous geology
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Research on the Application of Flash Animation Technology in Digital Media
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作者 Yong Zhang Peng Li 《International Journal of Technology Management》 2014年第5期115-117,共3页
This article first respectively introduces the characteristics of product design and digital media technology, combined with knowledge of the new economic background and user participation trends in innovation, analyz... This article first respectively introduces the characteristics of product design and digital media technology, combined with knowledge of the new economic background and user participation trends in innovation, analyzed the shortcomings of traditional design expression and digital media technology, through the use of digital media flash design expression and method, to solve the problem of traditional design expression. Finally, through the expression model of digital media and interactive animation based on flash animation technology, showed that flash obtained the rapid development and application in the multimedia platform. 展开更多
关键词 Digital media Flash animation technology interactive animation
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Development and Applications of Simulation Technology 被引量:1
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作者 WangZicai 《工程科学(英文版)》 2004年第2期33-37,共5页
The developing process of simulation technology is discussed in view of its development, maturation and further development. The applications of simulation technology in the fields of national economy are introduced. ... The developing process of simulation technology is discussed in view of its development, maturation and further development. The applications of simulation technology in the fields of national economy are introduced. Finally, the level and status quo of simulation technology home and overseas are analyzed, and its future trend in the new century is presented. 展开更多
关键词 系统仿真 分布式相互模拟 军事领域 工业 武器设备 仿真技术 计算机 网络技术
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Interactive Media Visual Interpretation of Traditional Chinese Graphics in Urban Public Spaces
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作者 Fu Zhang 《Journal of Electronic Research and Application》 2024年第3期42-46,共5页
This paper focuses on the application of interactive media technology in the visual interpretation of traditional graphic urban public spaces in China.Case studies and practical exploration show that interactive media... This paper focuses on the application of interactive media technology in the visual interpretation of traditional graphic urban public spaces in China.Case studies and practical exploration show that interactive media technologies such as projection mapping,interactive devices,virtual reality technology,etc.,have realized the diversity of traditional graphics display forms in urban public space.The rich interactive experience design enhances the sense of participation and experience of urban citizens and tourists and promotes the visual culture transmission of traditional Chinese graphics.The future urban public space exhibition is destined to continue to deepen the integration of technology and graphics,promote the visual communication of traditional Chinese graphics visual interpretation in urban public space,and promote sustainable innovation in cultural output in urban public space exhibitions around the world. 展开更多
关键词 Motion graphic design Public space interactive media technology
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Numerical Modeling of Ship-Ice-Water Interaction for Freerunning Ships in Pack Ice
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作者 ZOU Ming ZOU Zao−jian +1 位作者 ZOU Lu ZHU Sheng−tao 《船舶力学》 北大核心 2025年第6期878-887,共10页
Ice-going ships play a crucial role in polar transportation and resource extraction.Different from the existing modeling approach which assumes that ships remain stationary,dynamic overset grid technology and DFBI(Dyn... Ice-going ships play a crucial role in polar transportation and resource extraction.Different from the existing modeling approach which assumes that ships remain stationary,dynamic overset grid technology and DFBI(Dynamic Fluid-Body Interaction)method are employed in this paper to enable the free-running motion of the ship in modeling.A numerical model capable of simulating a ship navigating through pack ice area is proposed,which uses Computational Fluid Dynamics(CFD)method to solve the flow field and applies the Discrete Element Method(DEM)to simulate ship-ice and ice-ice interactions.Besides,the proposed high-precision method for generating pack ice area can be used in conjunction with the proposed numerical model.By comparing the numerical results with the available model test data and experimental observations,the effectiveness of the numerical model is validated,demonstrating its strong capability of predicting resistance and simulating ship navigation in pack ice,as well as its significant potential and applicability for further studies. 展开更多
关键词 pack ice ship-ice-water interaction CFD-DEM dynamic overset grid technology ship resistance
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Analysis of the Construction of Teacher-Student Interaction Mode in Piano Teaching in Normal Universities
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作者 Zitong Li 《Journal of Contemporary Educational Research》 2025年第4期81-90,共10页
In the modern higher education music curriculum system,the teacher-student interaction mode is a key factor affecting the effectiveness of piano teaching.However,the current teacher-student interaction mode in piano t... In the modern higher education music curriculum system,the teacher-student interaction mode is a key factor affecting the effectiveness of piano teaching.However,the current teacher-student interaction mode in piano teaching still has limitations,such as one-way transmission and a lack of personalized feedback.Based on constructivist learning theory and social interaction theory,combined with information technology,this paper explores the optimization strategy of interaction mode in the piano teaching process of normal universities.This study adopts classroom observation and interview methods to analyze the impact of different interaction modes on students’piano learning effectiveness,learning engagement,and autonomous learning ability.The research results show that the constructivist interactive teaching mode supported by information technology can significantly enhance students’interest in learning and playing skills,optimize the classroom teaching atmosphere,and promote the improvement of their comprehensive literacy. 展开更多
关键词 Piano teaching interactive teaching mode CONSTRUCTIVISM Information technology Autonomous learning
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Multi-scale information fusion and decoupled representation learning for robust microbe-disease interaction prediction
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作者 Wentao Wang Qiaoying Yan +5 位作者 Qingquan Liao Xinyuan Jin Yinyin Gong Linlin Zhuo Xiangzheng Fu Dongsheng Cao 《Journal of Pharmaceutical Analysis》 2025年第8期1738-1752,共15页
Research indicates that microbe activity within the human body significantly influences health by being closely linked to various diseases.Accurately predicting microbe-disease interactions(MDIs)offers critical insigh... Research indicates that microbe activity within the human body significantly influences health by being closely linked to various diseases.Accurately predicting microbe-disease interactions(MDIs)offers critical insights for disease intervention and pharmaceutical research.Current advanced AI-based technologies automatically generate robust representations of microbes and diseases,enabling effective MDI predictions.However,these models continue to face significant challenges.A major issue is their reliance on complex feature extractors and classifiers,which substantially diminishes the models’generalizability.To address this,we introduce a novel graph autoencoder framework that utilizes decoupled representation learning and multi-scale information fusion strategies to efficiently infer potential MDIs.Initially,we randomly mask portions of the input microbe-disease graph based on Bernoulli distribution to boost self-supervised training and minimize noise-related performance degradation.Secondly,we employ decoupled representation learning technology,compelling the graph neural network(GNN)to independently learn the weights for each feature subspace,thus enhancing its expressive power.Finally,we implement multi-scale information fusion technology to amalgamate the multi-layer outputs of GNN,reducing information loss due to occlusion.Extensive experiments on public datasets demonstrate that our model significantly surpasses existing top MDI prediction models.This indicates that our model can accurately predict unknown MDIs and is likely to aid in disease discovery and precision pharmaceutical research.Code and data are accessible at:https://github.com/shmildsj/MDI-IFDRL. 展开更多
关键词 Microbe-disease interactions(MDIs) Pharmaceutical research AI-Based technologies Decoupled representation learning Multi-scale information fusion
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