With breakthroughs in data processing and pattern recognition through deep learning technologies,the use of advanced algorithmic models for analyzing and interpreting soil spectral information has provided an efficien...With breakthroughs in data processing and pattern recognition through deep learning technologies,the use of advanced algorithmic models for analyzing and interpreting soil spectral information has provided an efficient and economical method for soil quality assessment.However,traditional single-output networks exhibit limitations in the prediction process,particularly in their inability to fully utilize the correlations among various elements.As a result,single-output networks tend to be optimized for a single task,neglecting the interrelationships among different soil elements,which limits prediction accuracy and model generalizability.To overcome this limitation,in this study,a multi-task learning architecture with a progressive extraction network was implemented for the simultaneous prediction of multiple indicators in soil,including nitrogen(N),organic carbon(OC),calcium carbonate(CaCO 3),cation exchange capacity(CEC),and pH.Furthermore,while incorporating the Pearson correlation coefficient,convolutional neural networks,long short-term memory networks and attention mechanisms were combined to extract local abstract features from the original spectra,thereby further improving the model.This architecture is referred to as the Relevance-sharing Progressive Layered Extraction Network.The model employs an adaptive joint loss optimization method to update the weights of individual task losses in the multi-task learning training process.展开更多
In the management of land resources and the protection of cultivated land,the law enforcement of land satellite images is often used as one of the main means.In recent years,the policies and regulations of the law enf...In the management of land resources and the protection of cultivated land,the law enforcement of land satellite images is often used as one of the main means.In recent years,the policies and regulations of the law enforcement of land satellite images have become more and more strict and been adjusted increasingly frequently,playing a decisive role in preventing excessive non-agricultural and non-food urbanization.In the process of the law enforcement,the extraction of suspected illegal buildings is the most important and time-consuming content.Compared with the traditional deep learning model,fully convolutional networks(FCN)has a great advantage in remote sensing image processing because its input images are not limited by size,and both convolution and deconvolution are independent of the overall size of images.In this paper,an intelligent extraction model of suspected illegal buildings from land satellite images based on deep learning FCN was built.Kaiyuan City,Yunnan Province was taken as an example.The verification results show that the global accuracy of this model was 86.6%in the process of building extraction,and mean intersection over union(mIoU)was 73.6%.This study can provide reference for the extraction of suspected illegal buildings in the law enforcement work of land satellite images,and reduce the tedious manual operation to a certain extent.展开更多
A large number of network security breaches in IoT networks have demonstrated the unreliability of current Network Intrusion Detection Systems(NIDSs).Consequently,network interruptions and loss of sensitive data have ...A large number of network security breaches in IoT networks have demonstrated the unreliability of current Network Intrusion Detection Systems(NIDSs).Consequently,network interruptions and loss of sensitive data have occurred,which led to an active research area for improving NIDS technologies.In an analysis of related works,it was observed that most researchers aim to obtain better classification results by using a set of untried combinations of Feature Reduction(FR)and Machine Learning(ML)techniques on NIDS datasets.However,these datasets are different in feature sets,attack types,and network design.Therefore,this paper aims to discover whether these techniques can be generalised across various datasets.Six ML models are utilised:a Deep Feed Forward(DFF),Convolutional Neural Network(CNN),Recurrent Neural Network(RNN),Decision Tree(DT),Logistic Regression(LR),and Naive Bayes(NB).The accuracy of three Feature Extraction(FE)algorithms is detected;Principal Component Analysis(PCA),Auto-encoder(AE),and Linear Discriminant Analysis(LDA),are evaluated using three benchmark datasets:UNSW-NB15,ToN-IoT and CSE-CIC-IDS2018.Although PCA and AE algorithms have been widely used,the determination of their optimal number of extracted dimensions has been overlooked.The results indicate that no clear FE method or ML model can achieve the best scores for all datasets.The optimal number of extracted dimensions has been identified for each dataset,and LDA degrades the performance of the ML models on two datasets.The variance is used to analyse the extracted dimensions of LDA and PCA.Finally,this paper concludes that the choice of datasets significantly alters the performance of the applied techniques.We believe that a universal(benchmark)feature set is needed to facilitate further advancement and progress of research in this field.展开更多
The anti-hair loss mechanism of Aquilaria sinensis leaf extract(ASE)has been studied by using metabolomics and network pharmacology.Metabolomics was utilized to comprehensively identify the active constituents of ASE,...The anti-hair loss mechanism of Aquilaria sinensis leaf extract(ASE)has been studied by using metabolomics and network pharmacology.Metabolomics was utilized to comprehensively identify the active constituents of ASE,and the network pharmacology was used to elucidate their anti-hair loss mechanism,which was verified by molecular docking technology.572 active compounds were identified from the ASE by metabolomics methods,where there are 1447 corresponding targets and 492 targets related to hair loss,totaling 88 targets.20 core active substances were identified by constructing a network between common targets and active substances,which include vanillic acid,chorionic acid,caffeic acid and apigenin.The five key targets of TNF,TP53,IL6,PPARG,and EGFR were screened out by the PPI network analysis on 88 common targets.The GO and KEGG pathway enrichment analysis showed that the inflammation,hormone balance,cell growth,proliferation,apoptosis,and oxidative stress are involved.Molecular docking studies have confirmed the high binding affinity between core active compounds and key targets.The drug similarity assessment on these core compounds suggested that they have the potential to be used as potential hair loss treatment drugs.This study elucidates the complex molecular mechanism of ASE in treating hair loss,and provides a reference for the future applications in hair care products.展开更多
The complex network of fractures formed by randomly distributed natural fractures in hot-dry rocks(HDRs)complicates the heat transfer regularity of injected fluid.On the basis of the fracture network,exploring the cha...The complex network of fractures formed by randomly distributed natural fractures in hot-dry rocks(HDRs)complicates the heat transfer regularity of injected fluid.On the basis of the fracture network,exploring the characteristics of the fluid flow and heat transfer as influenced by different parameters helps enable efficient resource extraction and effectively promotes the construction of diversified energy utilization structures.Accordingly,accounting for the effect of the thermal shock on the evolution of the permeability of the rock matrix,a thermo-hydromechanical(THM)coupling model is developed to analyze the influences of fracture network characteristics on the heat extraction performance of HDRs.In addition,a large-scale injection and production physical simulation experiment is performed using a newly developed,in-house,large-scale true triaxial experimental system.The corresponding numerical model is established and validated.The good agreement between the numerical and experimental results verifies the reliability and accuracy of the proposed THM model.Subsequently,a two-dimensional model is established under complex fracture network conditions,taking,as a research object,the natural fracture characteristics of HDR in the Qinghai Gonghe Basin in combination with the regional geological information.The effects of different parameters,including the production well location,rock matrix permeability,injection rate,initial fracture width,and number of fractures,on the production temperature and heat extraction performance are systematically analyzed.The results indicate that an increase in the number of fractures,the distance between the injection well and the production well,or the width of the initial fractures leads to an improved heat extraction performance.The number of fractures increased from 11 horizontal fractures and 22 high-angle fractures to 35 horizontal fractures and 70 high-angle fractures,with a 20%increase in heat extraction rate.While the influence of the rock matrix permeability is not highly significant,it cannot be ignored.It is crucial to select an injection rate that is neither too low nor too high,taking into consideration economic factors.展开更多
Objective Forsythia suspensa has long been utilized in traditional Chinese medicine(TCM)for the treatment of IgA nephropathy(IgAN),the most prevalent form of primary glomerular disease.However,the precise mechanisms r...Objective Forsythia suspensa has long been utilized in traditional Chinese medicine(TCM)for the treatment of IgA nephropathy(IgAN),the most prevalent form of primary glomerular disease.However,the precise mechanisms remain inadequately understood.This study seeks to elucidate the underlying mechanisms of Forsythia suspensa extract(FSE)in the treatment of IgAN by employing an integrated approach that combines network pharmacology with in vivo experimental validation.Methods The chemical components of FSE were identified using high-performance liquid chromatography-mass spectrometry(HPLC–MS/MS).Additional chemical components and targets were determined through the Traditional Chinese Medicine Systems Pharmacology database.Potential therapeutic targets for IgAN were sourced from GeneCards and the Comparative Toxicogenomics Database.Subsequently,the enrichment analyses were conducted to evaluate the biological functions and pathways associated with the core targets.Finally,a mousemodel of IgAN was developed to validate the findings of the network pharmacology analysis.Results Through network analysis and HPLC–MS/MS,31 chemical components of FSE were identified.A total of 99 common targets were discovered between FSE and IgAN.The enrichment analyses suggested that FSE may mitigate IgAN primarily by inhibiting the TLR and NF-κB signaling pathways.In vivo experiments demonstrated that FSE reduced inflammation and preserved renal function in mice with IgAN through the Tolllike receptor 9(TLR9)/NF-κB pathway.Conclusion The integration of network pharmacology and animal experiments suggests that FSE alleviates renal inflammation and damage in IgAN through the TLR9/NF-κB signaling pathway.展开更多
Nowadays,ensuring thequality of networkserviceshas become increasingly vital.Experts are turning toknowledge graph technology,with a significant emphasis on entity extraction in the identification of device configurat...Nowadays,ensuring thequality of networkserviceshas become increasingly vital.Experts are turning toknowledge graph technology,with a significant emphasis on entity extraction in the identification of device configurations.This research paper presents a novel entity extraction method that leverages a combination of active learning and attention mechanisms.Initially,an improved active learning approach is employed to select the most valuable unlabeled samples,which are subsequently submitted for expert labeling.This approach successfully addresses the problems of isolated points and sample redundancy within the network configuration sample set.Then the labeled samples are utilized to train the model for network configuration entity extraction.Furthermore,the multi-head self-attention of the transformer model is enhanced by introducing the Adaptive Weighting method based on the Laplace mixture distribution.This enhancement enables the transformer model to dynamically adapt its focus to words in various positions,displaying exceptional adaptability to abnormal data and further elevating the accuracy of the proposed model.Through comparisons with Random Sampling(RANDOM),Maximum Normalized Log-Probability(MNLP),Least Confidence(LC),Token Entrop(TE),and Entropy Query by Bagging(EQB),the proposed method,Entropy Query by Bagging and Maximum Influence Active Learning(EQBMIAL),achieves comparable performance with only 40% of the samples on both datasets,while other algorithms require 50% of the samples.Furthermore,the entity extraction algorithm with the Adaptive Weighted Multi-head Attention mechanism(AW-MHA)is compared with BILSTM-CRF,Mutil_Attention-Bilstm-Crf,Deep_Neural_Model_NER and BERT_Transformer,achieving precision rates of 75.98% and 98.32% on the two datasets,respectively.Statistical tests demonstrate the statistical significance and effectiveness of the proposed algorithms in this paper.展开更多
In minimally invasive surgery,endoscopes or laparoscopes equipped with miniature cameras and tools are used to enter the human body for therapeutic purposes through small incisions or natural cavities.However,in clini...In minimally invasive surgery,endoscopes or laparoscopes equipped with miniature cameras and tools are used to enter the human body for therapeutic purposes through small incisions or natural cavities.However,in clinical operating environments,endoscopic images often suffer from challenges such as low texture,uneven illumination,and non-rigid structures,which affect feature observation and extraction.This can severely impact surgical navigation or clinical diagnosis due to missing feature points in endoscopic images,leading to treatment and postoperative recovery issues for patients.To address these challenges,this paper introduces,for the first time,a Cross-Channel Multi-Modal Adaptive Spatial Feature Fusion(ASFF)module based on the lightweight architecture of EfficientViT.Additionally,a novel lightweight feature extraction and matching network based on attention mechanism is proposed.This network dynamically adjusts attention weights for cross-modal information from grayscale images and optical flow images through a dual-branch Siamese network.It extracts static and dynamic information features ranging from low-level to high-level,and from local to global,ensuring robust feature extraction across different widths,noise levels,and blur scenarios.Global and local matching are performed through a multi-level cascaded attention mechanism,with cross-channel attention introduced to simultaneously extract low-level and high-level features.Extensive ablation experiments and comparative studies are conducted on the HyperKvasir,EAD,M2caiSeg,CVC-ClinicDB,and UCL synthetic datasets.Experimental results demonstrate that the proposed network improves upon the baseline EfficientViT-B3 model by 75.4%in accuracy(Acc),while also enhancing runtime performance and storage efficiency.When compared with the complex DenseDescriptor feature extraction network,the difference in Acc is less than 7.22%,and IoU calculation results on specific datasets outperform complex dense models.Furthermore,this method increases the F1 score by 33.2%and accelerates runtime by 70.2%.It is noteworthy that the speed of CMMCAN surpasses that of comparative lightweight models,with feature extraction and matching performance comparable to existing complex models but with faster speed and higher cost-effectiveness.展开更多
Deep neural network-based relational extraction research has made significant progress in recent years,andit provides data support for many natural language processing downstream tasks such as building knowledgegraph,...Deep neural network-based relational extraction research has made significant progress in recent years,andit provides data support for many natural language processing downstream tasks such as building knowledgegraph,sentiment analysis and question-answering systems.However,previous studies ignored much unusedstructural information in sentences that could enhance the performance of the relation extraction task.Moreover,most existing dependency-based models utilize self-attention to distinguish the importance of context,whichhardly deals withmultiple-structure information.To efficiently leverage multiple structure information,this paperproposes a dynamic structure attention mechanism model based on textual structure information,which deeplyintegrates word embedding,named entity recognition labels,part of speech,dependency tree and dependency typeinto a graph convolutional network.Specifically,our model extracts text features of different structures from theinput sentence.Textual Structure information Graph Convolutional Networks employs the dynamic structureattention mechanism to learn multi-structure attention,effectively distinguishing important contextual features invarious structural information.In addition,multi-structure weights are carefully designed as amergingmechanismin the different structure attention to dynamically adjust the final attention.This paper combines these featuresand trains a graph convolutional network for relation extraction.We experiment on supervised relation extractiondatasets including SemEval 2010 Task 8,TACRED,TACREV,and Re-TACED,the result significantly outperformsthe previous.展开更多
The integration of Unmanned Aerial Vehicles(UAVs)into Intelligent Transportation Systems(ITS)holds trans-formative potential for real-time traffic monitoring,a critical component of emerging smart city infrastructure....The integration of Unmanned Aerial Vehicles(UAVs)into Intelligent Transportation Systems(ITS)holds trans-formative potential for real-time traffic monitoring,a critical component of emerging smart city infrastructure.UAVs offer unique advantages over stationary traffic cameras,including greater flexibility in monitoring large and dynamic urban areas.However,detecting small,densely packed vehicles in UAV imagery remains a significant challenge due to occlusion,variations in lighting,and the complexity of urban landscapes.Conventional models often struggle with these issues,leading to inaccurate detections and reduced performance in practical applications.To address these challenges,this paper introduces CFEMNet,an advanced deep learning model specifically designed for high-precision vehicle detection in complex urban environments.CFEMNet is built on the High-Resolution Network(HRNet)architecture and integrates a Context-aware Feature Extraction Module(CFEM),which combines multi-scale feature learning with a novel Self-Attention and Convolution layer setup within a Multi-scale Feature Block(MFB).This combination allows CFEMNet to accurately capture fine-grained details across varying scales,crucial for detecting small or partially occluded vehicles.Furthermore,the model incorporates an Equivalent Feed-Forward Network(EFFN)Block to ensure robust extraction of both spatial and semantic features,enhancing its ability to distinguish vehicles from similar objects.To optimize computational efficiency,CFEMNet employs a local window adaptation of Multi-head Self-Attention(MSA),which reduces memory overhead without sacrificing detection accuracy.Extensive experimental evaluations on the UAVDT and VisDrone-DET2018 datasets confirm CFEMNet’s superior performance in vehicle detection compared to existing models.This new architecture establishes CFEMNet as a benchmark for UAV-enabled traffic management,offering enhanced precision,reduced computational demands,and scalability for deployment in smart city applications.The advancements presented in CFEMNet contribute significantly to the evolution of smart city technologies,providing a foundation for intelligent and responsive traffic management systems that can adapt to the dynamic demands of urban environments.展开更多
This study aims to identify a natural plant chemical with hypolipidemic effects that can be used to treat high cholesterol without adverse reactions.Through network pharmacology screening,it was found that Rosae Rugos...This study aims to identify a natural plant chemical with hypolipidemic effects that can be used to treat high cholesterol without adverse reactions.Through network pharmacology screening,it was found that Rosae Rugosae Flos(RF)flavonoids had potential therapeutic effects on hyperlipidemia and its mechanism of action was discussed.TCMSP and GeneCards databases were used to obtain active ingredients and disease targets.Venn diagrams were drawn to illustrate the findings.The interaction network diagram was created using Cytoscape 3.8.0 software.The PPI protein network was constructed using String.GO and KEGG enrichment analysis was performed using Metascape.The results revealed 2 active flavonoid ingredients and 60 potential targets in RF.The key targets,including CCL2,PPARG,and PPARA,were found to play a role in multiple pathways such as the AGE-RAGE signaling pathway,lipid and atherosclerosis,and cancer pathway in diabetic complications.The solvent extraction method was optimized for efficient flavonoid extraction based on network pharmacology prediction results.This was achieved through a single factor and orthogonal test,resulting in an optimum process with a reflux time of 1.5 h,a solid-liquid ratio of 1:13 g/mL,and an ethanol concentration of 50%.展开更多
In light of the limited efficacy of conventional methods for identifying pavement cracks and the absence of comprehensive depth and location data in two-dimensional photographs,this study presents an intelligent strat...In light of the limited efficacy of conventional methods for identifying pavement cracks and the absence of comprehensive depth and location data in two-dimensional photographs,this study presents an intelligent strategy for extracting road cracks.This methodology involves the integration of laser point cloud data obtained from a vehicle-mounted system and a panoramic sequence of images.The study employs a vehicle-mounted LiDAR measurement system to acquire laser point cloud and panoramic sequence image data simultaneously.A convolutional neural network is utilized to extract cracks from the panoramic sequence image.The extracted sequence image is then aligned with the laser point cloud,enabling the assignment of RGB information to the vehicle-mounted three dimensional(3D)point cloud and location information to the two dimensional(2D)panoramic image.Additionally,a threshold value is set based on the crack elevation change to extract the aligned roadway point cloud.The three-dimensional data pertaining to the cracks can be acquired.The experimental findings demonstrate that the use of convolutional neural networks has yielded noteworthy outcomes in the extraction of road cracks.The utilization of point cloud and image alignment techniques enables the extraction of precise location data pertaining to road cracks.This approach exhibits superior accuracy when compared to conventional methods.Moreover,it facilitates rapid and accurate identification and localization of road cracks,thereby playing a crucial role in ensuring road maintenance and traffic safety.Consequently,this technique finds extensive application in the domains of intelligent transportation and urbanization development.The technology exhibits significant promise for use in the domains of intelligent transportation and city development.展开更多
Choosing the right characteristic parameter is the key to fault diagnosis in analog circuit. The feature evaluation and extraction methods based on neural network are presented. Parameter evaluation of circuit feature...Choosing the right characteristic parameter is the key to fault diagnosis in analog circuit. The feature evaluation and extraction methods based on neural network are presented. Parameter evaluation of circuit features is realized by training results from neural network; the superior nonlinear mapping capability is competent for extracting fault features which are normalized and compressed subsequently. The complex classification problem on fault pattern recognition in analog circuit is transferred into feature processing stage by feature extraction based on neural network effectively, which improves the diagnosis efficiency. A fault diagnosis illustration validated this method.展开更多
Throught fusion of the mechanism modeling and the neural networks modeling,a compo- nent content soft-sensor,which is composed of the equilibrium calculation model for multi-component rare earth extraction and the err...Throught fusion of the mechanism modeling and the neural networks modeling,a compo- nent content soft-sensor,which is composed of the equilibrium calculation model for multi-component rare earth extraction and the error compensation model of fuzzy system,is proposed to solve the prob- lem that the component content in countercurrent rare-earth extraction process is hardly measured on-line.An industry experiment in the extraction Y process by HAB using this hybrid soft-sensor proves its effectiveness.展开更多
The development of precision agriculture demands high accuracy and efficiency of cultivated land information extraction. As a new means of monitoring the ground in recent years, unmanned aerial vehicle （UAV） low-hei...The development of precision agriculture demands high accuracy and efficiency of cultivated land information extraction. As a new means of monitoring the ground in recent years, unmanned aerial vehicle （UAV） low-height remote sensing technique, which is flexible, efficient with low cost and with high resolution, is widely applied to investing various resources. Based on this, a novel extraction method for cultivated land information based on Deep Convolutional Neural Network and Transfer Learning （DTCLE） was proposed. First, linear features （roads and ridges etc.） were excluded based on Deep Convolutional Neural Network （DCNN）. Next, feature extraction method learned from DCNN was used to cultivated land information extraction by introducing transfer learning mechanism. Last, cultivated land information extraction results were completed by the DTCLE and eCognifion for cultivated land information extraction （ECLE）. The location of the Pengzhou County and Guanghan County, Sichuan Province were selected for the experimental purpose. The experimental results showed that the overall precision for the experimental image 1, 2 and 3 （of extracting cultivated land） with the DTCLE method was 91.7%, 88.1% and 88.2% respectively, and the overall precision of ECLE is 9o.7%, 90.5% and 87.0%, respectively. Accuracy of DTCLE was equivalent to that of ECLE, and also outperformed ECLE in terms of integrity and continuity.展开更多
In metal cutting industry it is a common practice to search for optimal combination of cutting parameters in order to maximize the tool life for a fixed minimum value of material removal rate（MRR）. After the advent ...In metal cutting industry it is a common practice to search for optimal combination of cutting parameters in order to maximize the tool life for a fixed minimum value of material removal rate（MRR）. After the advent of high-speed milling（HSM） pro cess, lots of experimental and theoretical researches have been done for this purpose which mainly emphasized on the optimization of the cutting parameters. It is highly beneficial to convert raw data into a comprehensive knowledge-based expert system using fuzzy logic as the reasoning mechanism. In this paper an attempt has been presented for the extraction of the rules from fuzzy neural network（FNN） so as to have the most effective knowledge-base for given set of data. Experiments were conducted to determine the best values of cutting speeds that can maximize tool life for different combinations of input parameters. A fuzzy neural network was constructed based on the fuzzification of input parameters and the cutting speed. After training process, raw rule sets were extracted and a rule pruning approach was proposed to obtain concise linguistic rules. The estimation process with fuzzy inference showed that the optimized combination of fuzzy rules provided the estimation error of only 6.34 m/min as compared to 314 m/min of that of randomized combination of rule s.展开更多
In this paper, the estimation capacities of the response surface methodology (RSM) and artificial neural network (ANN), in a microwave-assisted extraction method to determine the amount of zinc in fish samples were in...In this paper, the estimation capacities of the response surface methodology (RSM) and artificial neural network (ANN), in a microwave-assisted extraction method to determine the amount of zinc in fish samples were investigated. The experiments were carried out based on a 3-level, 4-variable Box–Behnken design. The amount of zinc was considered as a function of four independent variables, namely irradiation power, irradiation time, nitric acid concentration, and temperature. The RSM results showed the quadratic polynomial model can be used to describe the relationship between the various factors and the response. Using the ANN analysis, the optimal configuration of the ANN model was found to be 4-10-1. After predicting the model using RSM and ANN, two methodologies were then compared for their predictive capabilities. The results showed that the ANN model is much more accurate in prediction as compared to the RSM.展开更多
The equilibrium model for multicomponent rare earth extraction is developed using neural networks, which combined with the material balance model could give online prediction of component content in countercurrent rar...The equilibrium model for multicomponent rare earth extraction is developed using neural networks, which combined with the material balance model could give online prediction of component content in countercurrent rare earth (extraction) production. Simulation experiments with industrial operation data prove the effectiveness of the hybrid soft-(sensor).展开更多
Maintaining a steady power supply requires accurate forecasting of solar irradiance,since clean energy resources do not provide steady power.The existing forecasting studies have examined the limited effects of weathe...Maintaining a steady power supply requires accurate forecasting of solar irradiance,since clean energy resources do not provide steady power.The existing forecasting studies have examined the limited effects of weather conditions on solar radiation such as temperature and precipitation utilizing convolutional neural network(CNN),but no comprehensive study has been conducted on concentrations of air pollutants along with weather conditions.This paper proposes a hybrid approach based on deep learning,expanding the feature set by adding new air pollution concentrations,and ranking these features to select and reduce their size to improve efficiency.In order to improve the accuracy of feature selection,a maximum-dependency and minimum-redundancy(mRMR)criterion is applied to the constructed feature space to identify and rank the features.The combination of air pollution data with weather conditions data has enabled the prediction of solar irradiance with a higher accuracy.An evaluation of the proposed approach is conducted in Istanbul over 12 months for 43791 discrete times,with the main purpose of analyzing air data,including particular matter(PM10 and PM25),carbon monoxide(CO),nitric oxide(NOX),nitrogen dioxide(NO_(2)),ozone(O₃),sulfur dioxide(SO_(2))using a CNN,a long short-term memory network(LSTM),and MRMR feature extraction.Compared with the benchmark models with root mean square error(RMSE)results of 76.2,60.3,41.3,32.4,there is a significant improvement with the RMSE result of 5.536.This hybrid model presented here offers high prediction accuracy,a wider feature set,and a novel approach based on air concentrations combined with weather conditions for solar irradiance prediction.展开更多
OBJECTIVE: To explore the pharmacodynamic effects and potential mechanisms of Shuangling extract against ulcerative colitis(UC). METHODS: The bioinformatics method was used to predict the active ingredients and action...OBJECTIVE: To explore the pharmacodynamic effects and potential mechanisms of Shuangling extract against ulcerative colitis(UC). METHODS: The bioinformatics method was used to predict the active ingredients and action targets of Shuangling extract against UC in mice. And the biological experiments such as serum biochemical indexes and histopathological staining were used to verify the pharmacological effect and mechanism of Shuangling extract against UC in mice. RESULTS: The Shuangling extract reduced the levels of seruminterleukin-1β(IL-1β), tumor necrosis factor-α(TNF-N), interleukin-6(IL-6) and other inflammatory factors in UC mice and inhibited the inflammatory response. AKT Serine/threonine Kinase 1 and IL-6 may be the main targets of the anti-UC action of Shuangling extract, and the TNF signaling pathway, Forkhead box O signaling pathway and T-cell receptor signaling pathway may be the main signaling pathways. CONCLUSION: The Shuangling extract could inhibit the inflammatory response induced by UC and regulate intestinal immune function through multiple targets and multiple channels, which provided a new option and theoretical basis for anti-UC.展开更多
文摘With breakthroughs in data processing and pattern recognition through deep learning technologies,the use of advanced algorithmic models for analyzing and interpreting soil spectral information has provided an efficient and economical method for soil quality assessment.However,traditional single-output networks exhibit limitations in the prediction process,particularly in their inability to fully utilize the correlations among various elements.As a result,single-output networks tend to be optimized for a single task,neglecting the interrelationships among different soil elements,which limits prediction accuracy and model generalizability.To overcome this limitation,in this study,a multi-task learning architecture with a progressive extraction network was implemented for the simultaneous prediction of multiple indicators in soil,including nitrogen(N),organic carbon(OC),calcium carbonate(CaCO 3),cation exchange capacity(CEC),and pH.Furthermore,while incorporating the Pearson correlation coefficient,convolutional neural networks,long short-term memory networks and attention mechanisms were combined to extract local abstract features from the original spectra,thereby further improving the model.This architecture is referred to as the Relevance-sharing Progressive Layered Extraction Network.The model employs an adaptive joint loss optimization method to update the weights of individual task losses in the multi-task learning training process.
文摘In the management of land resources and the protection of cultivated land,the law enforcement of land satellite images is often used as one of the main means.In recent years,the policies and regulations of the law enforcement of land satellite images have become more and more strict and been adjusted increasingly frequently,playing a decisive role in preventing excessive non-agricultural and non-food urbanization.In the process of the law enforcement,the extraction of suspected illegal buildings is the most important and time-consuming content.Compared with the traditional deep learning model,fully convolutional networks(FCN)has a great advantage in remote sensing image processing because its input images are not limited by size,and both convolution and deconvolution are independent of the overall size of images.In this paper,an intelligent extraction model of suspected illegal buildings from land satellite images based on deep learning FCN was built.Kaiyuan City,Yunnan Province was taken as an example.The verification results show that the global accuracy of this model was 86.6%in the process of building extraction,and mean intersection over union(mIoU)was 73.6%.This study can provide reference for the extraction of suspected illegal buildings in the law enforcement work of land satellite images,and reduce the tedious manual operation to a certain extent.
文摘A large number of network security breaches in IoT networks have demonstrated the unreliability of current Network Intrusion Detection Systems(NIDSs).Consequently,network interruptions and loss of sensitive data have occurred,which led to an active research area for improving NIDS technologies.In an analysis of related works,it was observed that most researchers aim to obtain better classification results by using a set of untried combinations of Feature Reduction(FR)and Machine Learning(ML)techniques on NIDS datasets.However,these datasets are different in feature sets,attack types,and network design.Therefore,this paper aims to discover whether these techniques can be generalised across various datasets.Six ML models are utilised:a Deep Feed Forward(DFF),Convolutional Neural Network(CNN),Recurrent Neural Network(RNN),Decision Tree(DT),Logistic Regression(LR),and Naive Bayes(NB).The accuracy of three Feature Extraction(FE)algorithms is detected;Principal Component Analysis(PCA),Auto-encoder(AE),and Linear Discriminant Analysis(LDA),are evaluated using three benchmark datasets:UNSW-NB15,ToN-IoT and CSE-CIC-IDS2018.Although PCA and AE algorithms have been widely used,the determination of their optimal number of extracted dimensions has been overlooked.The results indicate that no clear FE method or ML model can achieve the best scores for all datasets.The optimal number of extracted dimensions has been identified for each dataset,and LDA degrades the performance of the ML models on two datasets.The variance is used to analyse the extracted dimensions of LDA and PCA.Finally,this paper concludes that the choice of datasets significantly alters the performance of the applied techniques.We believe that a universal(benchmark)feature set is needed to facilitate further advancement and progress of research in this field.
文摘The anti-hair loss mechanism of Aquilaria sinensis leaf extract(ASE)has been studied by using metabolomics and network pharmacology.Metabolomics was utilized to comprehensively identify the active constituents of ASE,and the network pharmacology was used to elucidate their anti-hair loss mechanism,which was verified by molecular docking technology.572 active compounds were identified from the ASE by metabolomics methods,where there are 1447 corresponding targets and 492 targets related to hair loss,totaling 88 targets.20 core active substances were identified by constructing a network between common targets and active substances,which include vanillic acid,chorionic acid,caffeic acid and apigenin.The five key targets of TNF,TP53,IL6,PPARG,and EGFR were screened out by the PPI network analysis on 88 common targets.The GO and KEGG pathway enrichment analysis showed that the inflammation,hormone balance,cell growth,proliferation,apoptosis,and oxidative stress are involved.Molecular docking studies have confirmed the high binding affinity between core active compounds and key targets.The drug similarity assessment on these core compounds suggested that they have the potential to be used as potential hair loss treatment drugs.This study elucidates the complex molecular mechanism of ASE in treating hair loss,and provides a reference for the future applications in hair care products.
基金supported by the Major Program of National Natural Science Foundation of China(No.52192622)the State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Independent Research Project(No.SKLGP2022Z018).
文摘The complex network of fractures formed by randomly distributed natural fractures in hot-dry rocks(HDRs)complicates the heat transfer regularity of injected fluid.On the basis of the fracture network,exploring the characteristics of the fluid flow and heat transfer as influenced by different parameters helps enable efficient resource extraction and effectively promotes the construction of diversified energy utilization structures.Accordingly,accounting for the effect of the thermal shock on the evolution of the permeability of the rock matrix,a thermo-hydromechanical(THM)coupling model is developed to analyze the influences of fracture network characteristics on the heat extraction performance of HDRs.In addition,a large-scale injection and production physical simulation experiment is performed using a newly developed,in-house,large-scale true triaxial experimental system.The corresponding numerical model is established and validated.The good agreement between the numerical and experimental results verifies the reliability and accuracy of the proposed THM model.Subsequently,a two-dimensional model is established under complex fracture network conditions,taking,as a research object,the natural fracture characteristics of HDR in the Qinghai Gonghe Basin in combination with the regional geological information.The effects of different parameters,including the production well location,rock matrix permeability,injection rate,initial fracture width,and number of fractures,on the production temperature and heat extraction performance are systematically analyzed.The results indicate that an increase in the number of fractures,the distance between the injection well and the production well,or the width of the initial fractures leads to an improved heat extraction performance.The number of fractures increased from 11 horizontal fractures and 22 high-angle fractures to 35 horizontal fractures and 70 high-angle fractures,with a 20%increase in heat extraction rate.While the influence of the rock matrix permeability is not highly significant,it cannot be ignored.It is crucial to select an injection rate that is neither too low nor too high,taking into consideration economic factors.
基金supported by the Natural Science Foundation of China(82560923)Natural Science Foundation of InnerMongolia(2019MS08008)+1 种基金Natural Science Foundation of Inner Mongolia Joint Program(2023LHMS08075)General Project of Inner Mongolia Medical University(YKD2025MS026).
文摘Objective Forsythia suspensa has long been utilized in traditional Chinese medicine(TCM)for the treatment of IgA nephropathy(IgAN),the most prevalent form of primary glomerular disease.However,the precise mechanisms remain inadequately understood.This study seeks to elucidate the underlying mechanisms of Forsythia suspensa extract(FSE)in the treatment of IgAN by employing an integrated approach that combines network pharmacology with in vivo experimental validation.Methods The chemical components of FSE were identified using high-performance liquid chromatography-mass spectrometry(HPLC–MS/MS).Additional chemical components and targets were determined through the Traditional Chinese Medicine Systems Pharmacology database.Potential therapeutic targets for IgAN were sourced from GeneCards and the Comparative Toxicogenomics Database.Subsequently,the enrichment analyses were conducted to evaluate the biological functions and pathways associated with the core targets.Finally,a mousemodel of IgAN was developed to validate the findings of the network pharmacology analysis.Results Through network analysis and HPLC–MS/MS,31 chemical components of FSE were identified.A total of 99 common targets were discovered between FSE and IgAN.The enrichment analyses suggested that FSE may mitigate IgAN primarily by inhibiting the TLR and NF-κB signaling pathways.In vivo experiments demonstrated that FSE reduced inflammation and preserved renal function in mice with IgAN through the Tolllike receptor 9(TLR9)/NF-κB pathway.Conclusion The integration of network pharmacology and animal experiments suggests that FSE alleviates renal inflammation and damage in IgAN through the TLR9/NF-κB signaling pathway.
基金supported by the National Key R&D Program of China(2019YFB2103202).
文摘Nowadays,ensuring thequality of networkserviceshas become increasingly vital.Experts are turning toknowledge graph technology,with a significant emphasis on entity extraction in the identification of device configurations.This research paper presents a novel entity extraction method that leverages a combination of active learning and attention mechanisms.Initially,an improved active learning approach is employed to select the most valuable unlabeled samples,which are subsequently submitted for expert labeling.This approach successfully addresses the problems of isolated points and sample redundancy within the network configuration sample set.Then the labeled samples are utilized to train the model for network configuration entity extraction.Furthermore,the multi-head self-attention of the transformer model is enhanced by introducing the Adaptive Weighting method based on the Laplace mixture distribution.This enhancement enables the transformer model to dynamically adapt its focus to words in various positions,displaying exceptional adaptability to abnormal data and further elevating the accuracy of the proposed model.Through comparisons with Random Sampling(RANDOM),Maximum Normalized Log-Probability(MNLP),Least Confidence(LC),Token Entrop(TE),and Entropy Query by Bagging(EQB),the proposed method,Entropy Query by Bagging and Maximum Influence Active Learning(EQBMIAL),achieves comparable performance with only 40% of the samples on both datasets,while other algorithms require 50% of the samples.Furthermore,the entity extraction algorithm with the Adaptive Weighted Multi-head Attention mechanism(AW-MHA)is compared with BILSTM-CRF,Mutil_Attention-Bilstm-Crf,Deep_Neural_Model_NER and BERT_Transformer,achieving precision rates of 75.98% and 98.32% on the two datasets,respectively.Statistical tests demonstrate the statistical significance and effectiveness of the proposed algorithms in this paper.
基金This work was supported by Science and Technology Cooperation Special Project of Shijiazhuang(SJZZXA23005).
文摘In minimally invasive surgery,endoscopes or laparoscopes equipped with miniature cameras and tools are used to enter the human body for therapeutic purposes through small incisions or natural cavities.However,in clinical operating environments,endoscopic images often suffer from challenges such as low texture,uneven illumination,and non-rigid structures,which affect feature observation and extraction.This can severely impact surgical navigation or clinical diagnosis due to missing feature points in endoscopic images,leading to treatment and postoperative recovery issues for patients.To address these challenges,this paper introduces,for the first time,a Cross-Channel Multi-Modal Adaptive Spatial Feature Fusion(ASFF)module based on the lightweight architecture of EfficientViT.Additionally,a novel lightweight feature extraction and matching network based on attention mechanism is proposed.This network dynamically adjusts attention weights for cross-modal information from grayscale images and optical flow images through a dual-branch Siamese network.It extracts static and dynamic information features ranging from low-level to high-level,and from local to global,ensuring robust feature extraction across different widths,noise levels,and blur scenarios.Global and local matching are performed through a multi-level cascaded attention mechanism,with cross-channel attention introduced to simultaneously extract low-level and high-level features.Extensive ablation experiments and comparative studies are conducted on the HyperKvasir,EAD,M2caiSeg,CVC-ClinicDB,and UCL synthetic datasets.Experimental results demonstrate that the proposed network improves upon the baseline EfficientViT-B3 model by 75.4%in accuracy(Acc),while also enhancing runtime performance and storage efficiency.When compared with the complex DenseDescriptor feature extraction network,the difference in Acc is less than 7.22%,and IoU calculation results on specific datasets outperform complex dense models.Furthermore,this method increases the F1 score by 33.2%and accelerates runtime by 70.2%.It is noteworthy that the speed of CMMCAN surpasses that of comparative lightweight models,with feature extraction and matching performance comparable to existing complex models but with faster speed and higher cost-effectiveness.
文摘Deep neural network-based relational extraction research has made significant progress in recent years,andit provides data support for many natural language processing downstream tasks such as building knowledgegraph,sentiment analysis and question-answering systems.However,previous studies ignored much unusedstructural information in sentences that could enhance the performance of the relation extraction task.Moreover,most existing dependency-based models utilize self-attention to distinguish the importance of context,whichhardly deals withmultiple-structure information.To efficiently leverage multiple structure information,this paperproposes a dynamic structure attention mechanism model based on textual structure information,which deeplyintegrates word embedding,named entity recognition labels,part of speech,dependency tree and dependency typeinto a graph convolutional network.Specifically,our model extracts text features of different structures from theinput sentence.Textual Structure information Graph Convolutional Networks employs the dynamic structureattention mechanism to learn multi-structure attention,effectively distinguishing important contextual features invarious structural information.In addition,multi-structure weights are carefully designed as amergingmechanismin the different structure attention to dynamically adjust the final attention.This paper combines these featuresand trains a graph convolutional network for relation extraction.We experiment on supervised relation extractiondatasets including SemEval 2010 Task 8,TACRED,TACREV,and Re-TACED,the result significantly outperformsthe previous.
基金funded by the Deanship of Scientific Research at Northern Border University,Arar,Saudi Arabia through research group No.(RG-NBU-2022-1234).
文摘The integration of Unmanned Aerial Vehicles(UAVs)into Intelligent Transportation Systems(ITS)holds trans-formative potential for real-time traffic monitoring,a critical component of emerging smart city infrastructure.UAVs offer unique advantages over stationary traffic cameras,including greater flexibility in monitoring large and dynamic urban areas.However,detecting small,densely packed vehicles in UAV imagery remains a significant challenge due to occlusion,variations in lighting,and the complexity of urban landscapes.Conventional models often struggle with these issues,leading to inaccurate detections and reduced performance in practical applications.To address these challenges,this paper introduces CFEMNet,an advanced deep learning model specifically designed for high-precision vehicle detection in complex urban environments.CFEMNet is built on the High-Resolution Network(HRNet)architecture and integrates a Context-aware Feature Extraction Module(CFEM),which combines multi-scale feature learning with a novel Self-Attention and Convolution layer setup within a Multi-scale Feature Block(MFB).This combination allows CFEMNet to accurately capture fine-grained details across varying scales,crucial for detecting small or partially occluded vehicles.Furthermore,the model incorporates an Equivalent Feed-Forward Network(EFFN)Block to ensure robust extraction of both spatial and semantic features,enhancing its ability to distinguish vehicles from similar objects.To optimize computational efficiency,CFEMNet employs a local window adaptation of Multi-head Self-Attention(MSA),which reduces memory overhead without sacrificing detection accuracy.Extensive experimental evaluations on the UAVDT and VisDrone-DET2018 datasets confirm CFEMNet’s superior performance in vehicle detection compared to existing models.This new architecture establishes CFEMNet as a benchmark for UAV-enabled traffic management,offering enhanced precision,reduced computational demands,and scalability for deployment in smart city applications.The advancements presented in CFEMNet contribute significantly to the evolution of smart city technologies,providing a foundation for intelligent and responsive traffic management systems that can adapt to the dynamic demands of urban environments.
文摘This study aims to identify a natural plant chemical with hypolipidemic effects that can be used to treat high cholesterol without adverse reactions.Through network pharmacology screening,it was found that Rosae Rugosae Flos(RF)flavonoids had potential therapeutic effects on hyperlipidemia and its mechanism of action was discussed.TCMSP and GeneCards databases were used to obtain active ingredients and disease targets.Venn diagrams were drawn to illustrate the findings.The interaction network diagram was created using Cytoscape 3.8.0 software.The PPI protein network was constructed using String.GO and KEGG enrichment analysis was performed using Metascape.The results revealed 2 active flavonoid ingredients and 60 potential targets in RF.The key targets,including CCL2,PPARG,and PPARA,were found to play a role in multiple pathways such as the AGE-RAGE signaling pathway,lipid and atherosclerosis,and cancer pathway in diabetic complications.The solvent extraction method was optimized for efficient flavonoid extraction based on network pharmacology prediction results.This was achieved through a single factor and orthogonal test,resulting in an optimum process with a reflux time of 1.5 h,a solid-liquid ratio of 1:13 g/mL,and an ethanol concentration of 50%.
基金founded by National Key R&D Program of China (No.2021YFB2601200)National Natural Science Foundation of China (No.42171416)Teacher Support Program for Pyramid Talent Training Project of Beijing University of Civil Engineering and Architecture (No.JDJQ20200307).
文摘In light of the limited efficacy of conventional methods for identifying pavement cracks and the absence of comprehensive depth and location data in two-dimensional photographs,this study presents an intelligent strategy for extracting road cracks.This methodology involves the integration of laser point cloud data obtained from a vehicle-mounted system and a panoramic sequence of images.The study employs a vehicle-mounted LiDAR measurement system to acquire laser point cloud and panoramic sequence image data simultaneously.A convolutional neural network is utilized to extract cracks from the panoramic sequence image.The extracted sequence image is then aligned with the laser point cloud,enabling the assignment of RGB information to the vehicle-mounted three dimensional(3D)point cloud and location information to the two dimensional(2D)panoramic image.Additionally,a threshold value is set based on the crack elevation change to extract the aligned roadway point cloud.The three-dimensional data pertaining to the cracks can be acquired.The experimental findings demonstrate that the use of convolutional neural networks has yielded noteworthy outcomes in the extraction of road cracks.The utilization of point cloud and image alignment techniques enables the extraction of precise location data pertaining to road cracks.This approach exhibits superior accuracy when compared to conventional methods.Moreover,it facilitates rapid and accurate identification and localization of road cracks,thereby playing a crucial role in ensuring road maintenance and traffic safety.Consequently,this technique finds extensive application in the domains of intelligent transportation and urbanization development.The technology exhibits significant promise for use in the domains of intelligent transportation and city development.
基金the National Natural Science Fundation of China (60372001 90407007)the Ph. D. Programs Foundation of Ministry of Education of China (20030614006).
文摘Choosing the right characteristic parameter is the key to fault diagnosis in analog circuit. The feature evaluation and extraction methods based on neural network are presented. Parameter evaluation of circuit features is realized by training results from neural network; the superior nonlinear mapping capability is competent for extracting fault features which are normalized and compressed subsequently. The complex classification problem on fault pattern recognition in analog circuit is transferred into feature processing stage by feature extraction based on neural network effectively, which improves the diagnosis efficiency. A fault diagnosis illustration validated this method.
基金Supported by National Natural Science Foundation of P.R.China(50474020,60534010,60504006)
文摘Throught fusion of the mechanism modeling and the neural networks modeling,a compo- nent content soft-sensor,which is composed of the equilibrium calculation model for multi-component rare earth extraction and the error compensation model of fuzzy system,is proposed to solve the prob- lem that the component content in countercurrent rare-earth extraction process is hardly measured on-line.An industry experiment in the extraction Y process by HAB using this hybrid soft-sensor proves its effectiveness.
基金supported by the Fundamental Research Funds for the Central Universities of China(Grant No.2013SCU11006)the Key Laboratory of Digital Mapping and Land Information Application of National Administration of Surveying,Mapping and Geoinformation of China(Grant NO.DM2014SC02)the Key Laboratory of Geospecial Information Technology,Ministry of Land and Resources of China(Grant NO.KLGSIT201504)
文摘The development of precision agriculture demands high accuracy and efficiency of cultivated land information extraction. As a new means of monitoring the ground in recent years, unmanned aerial vehicle （UAV） low-height remote sensing technique, which is flexible, efficient with low cost and with high resolution, is widely applied to investing various resources. Based on this, a novel extraction method for cultivated land information based on Deep Convolutional Neural Network and Transfer Learning （DTCLE） was proposed. First, linear features （roads and ridges etc.） were excluded based on Deep Convolutional Neural Network （DCNN）. Next, feature extraction method learned from DCNN was used to cultivated land information extraction by introducing transfer learning mechanism. Last, cultivated land information extraction results were completed by the DTCLE and eCognifion for cultivated land information extraction （ECLE）. The location of the Pengzhou County and Guanghan County, Sichuan Province were selected for the experimental purpose. The experimental results showed that the overall precision for the experimental image 1, 2 and 3 （of extracting cultivated land） with the DTCLE method was 91.7%, 88.1% and 88.2% respectively, and the overall precision of ECLE is 9o.7%, 90.5% and 87.0%, respectively. Accuracy of DTCLE was equivalent to that of ECLE, and also outperformed ECLE in terms of integrity and continuity.
基金supported by International Science and Technology Cooperation project (Grant No. 2008DFA71750)
文摘In metal cutting industry it is a common practice to search for optimal combination of cutting parameters in order to maximize the tool life for a fixed minimum value of material removal rate（MRR）. After the advent of high-speed milling（HSM） pro cess, lots of experimental and theoretical researches have been done for this purpose which mainly emphasized on the optimization of the cutting parameters. It is highly beneficial to convert raw data into a comprehensive knowledge-based expert system using fuzzy logic as the reasoning mechanism. In this paper an attempt has been presented for the extraction of the rules from fuzzy neural network（FNN） so as to have the most effective knowledge-base for given set of data. Experiments were conducted to determine the best values of cutting speeds that can maximize tool life for different combinations of input parameters. A fuzzy neural network was constructed based on the fuzzification of input parameters and the cutting speed. After training process, raw rule sets were extracted and a rule pruning approach was proposed to obtain concise linguistic rules. The estimation process with fuzzy inference showed that the optimized combination of fuzzy rules provided the estimation error of only 6.34 m/min as compared to 314 m/min of that of randomized combination of rule s.
文摘In this paper, the estimation capacities of the response surface methodology (RSM) and artificial neural network (ANN), in a microwave-assisted extraction method to determine the amount of zinc in fish samples were investigated. The experiments were carried out based on a 3-level, 4-variable Box–Behnken design. The amount of zinc was considered as a function of four independent variables, namely irradiation power, irradiation time, nitric acid concentration, and temperature. The RSM results showed the quadratic polynomial model can be used to describe the relationship between the various factors and the response. Using the ANN analysis, the optimal configuration of the ANN model was found to be 4-10-1. After predicting the model using RSM and ANN, two methodologies were then compared for their predictive capabilities. The results showed that the ANN model is much more accurate in prediction as compared to the RSM.
基金ProjectsupportedbytheNationalTenthFive Year PlanofKeyTechnology (2 0 0 2BA3 15A)
文摘The equilibrium model for multicomponent rare earth extraction is developed using neural networks, which combined with the material balance model could give online prediction of component content in countercurrent rare earth (extraction) production. Simulation experiments with industrial operation data prove the effectiveness of the hybrid soft-(sensor).
文摘Maintaining a steady power supply requires accurate forecasting of solar irradiance,since clean energy resources do not provide steady power.The existing forecasting studies have examined the limited effects of weather conditions on solar radiation such as temperature and precipitation utilizing convolutional neural network(CNN),but no comprehensive study has been conducted on concentrations of air pollutants along with weather conditions.This paper proposes a hybrid approach based on deep learning,expanding the feature set by adding new air pollution concentrations,and ranking these features to select and reduce their size to improve efficiency.In order to improve the accuracy of feature selection,a maximum-dependency and minimum-redundancy(mRMR)criterion is applied to the constructed feature space to identify and rank the features.The combination of air pollution data with weather conditions data has enabled the prediction of solar irradiance with a higher accuracy.An evaluation of the proposed approach is conducted in Istanbul over 12 months for 43791 discrete times,with the main purpose of analyzing air data,including particular matter(PM10 and PM25),carbon monoxide(CO),nitric oxide(NOX),nitrogen dioxide(NO_(2)),ozone(O₃),sulfur dioxide(SO_(2))using a CNN,a long short-term memory network(LSTM),and MRMR feature extraction.Compared with the benchmark models with root mean square error(RMSE)results of 76.2,60.3,41.3,32.4,there is a significant improvement with the RMSE result of 5.536.This hybrid model presented here offers high prediction accuracy,a wider feature set,and a novel approach based on air concentrations combined with weather conditions for solar irradiance prediction.
基金the Innovation Team and Talents Support Program of National Administration of Traditional Chinese Medicine:Construction and Practice of Pharmacovigilance Theory System in Line with the Characteristics of Traditional Chinese Medicine (No. ZYYCXTD-C-202005-11)the National Leading Talents Support Plan of Traditional Chinese Medicine 'Qihuang Scholar' Plan:Chinese Medicine Inheritance and Innovation "One Hundred Million" Talent Project (Qihuang Project) Qihuang Scholars (No. 1040063320004)。
文摘OBJECTIVE: To explore the pharmacodynamic effects and potential mechanisms of Shuangling extract against ulcerative colitis(UC). METHODS: The bioinformatics method was used to predict the active ingredients and action targets of Shuangling extract against UC in mice. And the biological experiments such as serum biochemical indexes and histopathological staining were used to verify the pharmacological effect and mechanism of Shuangling extract against UC in mice. RESULTS: The Shuangling extract reduced the levels of seruminterleukin-1β(IL-1β), tumor necrosis factor-α(TNF-N), interleukin-6(IL-6) and other inflammatory factors in UC mice and inhibited the inflammatory response. AKT Serine/threonine Kinase 1 and IL-6 may be the main targets of the anti-UC action of Shuangling extract, and the TNF signaling pathway, Forkhead box O signaling pathway and T-cell receptor signaling pathway may be the main signaling pathways. CONCLUSION: The Shuangling extract could inhibit the inflammatory response induced by UC and regulate intestinal immune function through multiple targets and multiple channels, which provided a new option and theoretical basis for anti-UC.
