Complex network models are frequently employed for simulating and studyingdiverse real-world complex systems.Among these models,scale-free networks typically exhibit greater fragility to malicious attacks.Consequently...Complex network models are frequently employed for simulating and studyingdiverse real-world complex systems.Among these models,scale-free networks typically exhibit greater fragility to malicious attacks.Consequently,enhancing the robustness of scale-free networks has become a pressing issue.To address this problem,this paper proposes a Multi-Granularity Integration Algorithm(MGIA),which aims to improve the robustness of scale-free networks while keeping the initial degree of each node unchanged,ensuring network connectivity and avoiding the generation of multiple edges.The algorithm generates a multi-granularity structure from the initial network to be optimized,then uses different optimization strategies to optimize the networks at various granular layers in this structure,and finally realizes the information exchange between different granular layers,thereby further enhancing the optimization effect.We propose new network refresh,crossover,and mutation operators to ensure that the optimized network satisfies the given constraints.Meanwhile,we propose new network similarity and network dissimilarity evaluation metrics to improve the effectiveness of the optimization operators in the algorithm.In the experiments,the MGIA enhances the robustness of the scale-free network by 67.6%.This improvement is approximately 17.2%higher than the optimization effects achieved by eight currently existing complex network robustness optimization algorithms.展开更多
The multi-granularity spatial-temporal-related access control（MSTAC） model was proposed to meet the spatial access control requirements for the service-oriented spatial data infrastructure（SDI）. MSTAC extends the ...The multi-granularity spatial-temporal-related access control（MSTAC） model was proposed to meet the spatial access control requirements for the service-oriented spatial data infrastructure（SDI）. MSTAC extends the attribute constraints of role-based access control（RBAC）, which includes the user＇s location attribute, the role＇s time constraint, the layer vector constraint of a map class, the scale and time constraints of a geographic layer, the topological constraints of geographic features, the semantic attribute expression constraints of geographic features, and the field constraint of feature views. Through this model, authorized users would be limited to access different granularity spatial datasets, such as the map granularity, the graphic layer granularity, the feature object granularity and the feature view granularity. Finally, the MSTAC model is achieved in a web GIS, which shows the positive and negative authorizations to different services in different data granularities and time periods.展开更多
Visible-infrared Cross-modality Person Re-identification(VI-ReID)is a critical technology in smart public facilities such as cities,campuses and libraries.It aims to match pedestrians in visible light and infrared ima...Visible-infrared Cross-modality Person Re-identification(VI-ReID)is a critical technology in smart public facilities such as cities,campuses and libraries.It aims to match pedestrians in visible light and infrared images for video surveillance,which poses a challenge in exploring cross-modal shared information accurately and efficiently.Therefore,multi-granularity feature learning methods have been applied in VI-ReID to extract potential multi-granularity semantic information related to pedestrian body structure attributes.However,existing research mainly uses traditional dual-stream fusion networks and overlooks the core of cross-modal learning networks,the fusion module.This paper introduces a novel network called the Augmented Deep Multi-Granularity Pose-Aware Feature Fusion Network(ADMPFF-Net),incorporating the Multi-Granularity Pose-Aware Feature Fusion(MPFF)module to generate discriminative representations.MPFF efficiently explores and learns global and local features with multi-level semantic information by inserting disentangling and duplicating blocks into the fusion module of the backbone network.ADMPFF-Net also provides a new perspective for designing multi-granularity learning networks.By incorporating the multi-granularity feature disentanglement(mGFD)and posture information segmentation(pIS)strategies,it extracts more representative features concerning body structure information.The Local Information Enhancement(LIE)module augments high-performance features in VI-ReID,and the multi-granularity joint loss supervises model training for objective feature learning.Experimental results on two public datasets show that ADMPFF-Net efficiently constructs pedestrian feature representations and enhances the accuracy of VI-ReID.展开更多
Coronavirus disease 2019(COVID-19)is continuing to spread globally and still poses a great threat to human health.Since its outbreak,it has had catastrophic effects on human society.A visual method of analyzing COVID-...Coronavirus disease 2019(COVID-19)is continuing to spread globally and still poses a great threat to human health.Since its outbreak,it has had catastrophic effects on human society.A visual method of analyzing COVID-19 case information using spatio-temporal objects with multi-granularity is proposed based on the officially provided case information.This analysis reveals the spread of the epidemic,from the perspective of spatio-temporal objects,to provide references for related research and the formulation of epidemic prevention and control measures.The case information is abstracted,descripted,represented,and analyzed in the form of spatio-temporal objects through the construction of spatio-temporal case objects,multi-level visual expressions,and spatial correlation analysis.The rationality of the method is verified through visualization scenarios of case information statistics for China,Henan cases,and cases related to Shulan.The results show that the proposed method is helpful in the research and judgment of the development trend of the epidemic,the discovery of the transmission law,and the spatial traceability of the cases.It has a good portability and good expansion performance,so it can be used for the visual analysis of case information for other regions and can help users quickly discover the potential knowledge this information contains.展开更多
Accurate forecasting of time series is crucial across various domains.Many prediction tasks rely on effectively segmenting,matching,and time series data alignment.For instance,regardless of time series with the same g...Accurate forecasting of time series is crucial across various domains.Many prediction tasks rely on effectively segmenting,matching,and time series data alignment.For instance,regardless of time series with the same granularity,segmenting them into different granularity events can effectively mitigate the impact of varying time scales on prediction accuracy.However,these events of varying granularity frequently intersect with each other,which may possess unequal durations.Even minor differences can result in significant errors when matching time series with future trends.Besides,directly using matched events but unaligned events as state vectors in machine learning-based prediction models can lead to insufficient prediction accuracy.Therefore,this paper proposes a short-term forecasting method for time series based on a multi-granularity event,MGE-SP(multi-granularity event-based short-termprediction).First,amethodological framework for MGE-SP established guides the implementation steps.The framework consists of three key steps,including multi-granularity event matching based on the LTF(latest time first)strategy,multi-granularity event alignment using a piecewise aggregate approximation based on the compression ratio,and a short-term prediction model based on XGBoost.The data from a nationwide online car-hailing service in China ensures the method’s reliability.The average RMSE(root mean square error)and MAE(mean absolute error)of the proposed method are 3.204 and 2.360,lower than the respective values of 4.056 and 3.101 obtained using theARIMA(autoregressive integratedmoving average)method,as well as the values of 4.278 and 2.994 obtained using k-means-SVR(support vector regression)method.The other experiment is conducted on stock data froma public data set.The proposed method achieved an average RMSE and MAE of 0.836 and 0.696,lower than the respective values of 1.019 and 0.844 obtained using the ARIMA method,as well as the values of 1.350 and 1.172 obtained using the k-means-SVR method.展开更多
A novel multi-granularity flexible-grid switching optical-node architecture is proposed in this paper.In our system,the photonic lanterns are used as mode division multiplexing/demultiplexing(MD-Mux/MD-Demux)for selec...A novel multi-granularity flexible-grid switching optical-node architecture is proposed in this paper.In our system,the photonic lanterns are used as mode division multiplexing/demultiplexing(MD-Mux/MD-Demux)for selecting mode.The wavelength division multiplexer/demultiplexer(WDMux/WD-Demux)and the fiber bragg gratings(FBGs)are used to select wavelength channels with the various grid.The experimental results show that the transmission bandwidth covers the C+L band,the average transmission loss is-13.4 dB,and the average crosstalk is-30.5 dB.The optical-node architecture is suit for mode division multiplexing(MDM)optical communication system.展开更多
Extracting valuable information frombiomedical texts is one of the current research hotspots of concern to a wide range of scholars.The biomedical corpus contains numerous complex long sentences and overlapping relati...Extracting valuable information frombiomedical texts is one of the current research hotspots of concern to a wide range of scholars.The biomedical corpus contains numerous complex long sentences and overlapping relational triples,making most generalized domain joint modeling methods difficult to apply effectively in this field.For a complex semantic environment in biomedical texts,in this paper,we propose a novel perspective to perform joint entity and relation extraction;existing studies divide the relation triples into several steps or modules.However,the three elements in the relation triples are interdependent and inseparable,so we regard joint extraction as a tripartite classification problem.At the same time,fromthe perspective of triple classification,we design amulti-granularity 2D convolution to refine the word pair table and better utilize the dependencies between biomedical word pairs.Finally,we use a biaffine predictor to assist in predicting the labels of word pairs for relation extraction.Our model(MCTPL)Multi-granularity Convolutional Tokens Pairs of Labeling better utilizes the elements of triples and improves the ability to extract overlapping triples compared to previous approaches.Finally,we evaluated our model on two publicly accessible datasets.The experimental results show that our model’s ability to extract relation triples on the CPI dataset improves the F1 score by 2.34%compared to the current optimal model.On the DDI dataset,the F1 value improves the F1 value by 1.68%compared to the current optimal model.Our model achieved state-of-the-art performance compared to other baseline models in biomedical text entity relation extraction.展开更多
This paper introduces a multi-granularity locking model (MGL) for concurrency control in object-oriented database system briefiy, and presents a MGL model formally. Four lockingscheduling algorithms for MGL are propos...This paper introduces a multi-granularity locking model (MGL) for concurrency control in object-oriented database system briefiy, and presents a MGL model formally. Four lockingscheduling algorithms for MGL are proposed in the paper. The ideas of single queue scheduling(SQS) and dual queue scheduling (DQS) are proposed and the algorithm and the performance evaluation for these two scheduling are presented in some paper. This paper describes a new idea of thescheduling for MGL, compatible requests first (CRF). Combining the new idea with SQS and DQS,we propose two new scheduling algorithms called CRFS and CRFD. After describing the simulationmodel, this paper illustrates the comparisons of the performance among these four algorithms. Asshown in the experiments, DQS has better performance than SQS, CRFD is better than DQS, CRFSperforms better than SQS, and CRFS is the best one of these four scheduling algorithms.展开更多
The research on named entity recognition for label-few domain is becoming increasingly important.In this paper,a novel algorithm,positive unlabeled named entity recognition(PUNER)with multi-granularity language inform...The research on named entity recognition for label-few domain is becoming increasingly important.In this paper,a novel algorithm,positive unlabeled named entity recognition(PUNER)with multi-granularity language information,is proposed,which combines positive unlabeled(PU)learning and deep learning to obtain the multi-granularity language information from a few labeled in-stances and many unlabeled instances to recognize named entities.First,PUNER selects reliable negative instances from unlabeled datasets,uses positive instances and a corresponding number of negative instances to train the PU learning classifier,and iterates continuously to label all unlabeled instances.Second,a neural network-based architecture to implement the PU learning classifier is used,and comprehensive text semantics through multi-granular language information are obtained,which helps the classifier correctly recognize named entities.Performance tests of the PUNER are carried out on three multilingual NER datasets,which are CoNLL2003,CoNLL 2002 and SIGHAN Bakeoff 2006.Experimental results demonstrate the effectiveness of the proposed PUNER.展开更多
The two universes multi-granularity fuzzy rough set model is an effective tool for handling uncertainty problems between two domains with the help of binary fuzzy relations. This article applies the idea of neighborho...The two universes multi-granularity fuzzy rough set model is an effective tool for handling uncertainty problems between two domains with the help of binary fuzzy relations. This article applies the idea of neighborhood rough sets to two universes multi-granularity fuzzy rough sets, and discusses the two-universes multi-granularity neighborhood fuzzy rough set model. Firstly, the upper and lower approximation operators are defined in the two universes multi-granularity neighborhood fuzzy rough set model. Secondly, the properties of the upper and lower approximation operators are discussed. Finally, the properties of the two universes multi-granularity neighborhood fuzzy rough set model are verified through case studies.展开更多
To effectively deal with fuzzy and uncertain information in public engineering emergencies,an emergency decision-making method based on multi-granularity language information is proposed.Firstly,decision makers select...To effectively deal with fuzzy and uncertain information in public engineering emergencies,an emergency decision-making method based on multi-granularity language information is proposed.Firstly,decision makers select the appropriate language phrase set according to their own situation,give the preference information of the weight of each key indicator,and then transform the multi-granularity language information through consistency.On this basis,the sequential optimization technology of the approximately ideal scheme is introduced to obtain the weight coefficient of each key indicator.Subsequently,the weighted average operator is used to aggregate the preference information of each alternative scheme with the relative importance of decision-makers and the weight of key indicators in sequence,and the comprehensive evaluation value of each scheme is obtained to determine the optimal scheme.Lastly,the effectiveness and practicability of the method are verified by taking the earthwork collapse accident in the construction of a reservoir as an example.展开更多
In view of the complexity of emergencies and the subjectivity of decision-makers,a method of determining key emergency indicators based on multi-granularity uncertainty language is proposed.Firstly,decision members us...In view of the complexity of emergencies and the subjectivity of decision-makers,a method of determining key emergency indicators based on multi-granularity uncertainty language is proposed.Firstly,decision members use preferred uncertain language phrases to represent the importance of each key indicator and use transformation functions to carry out the consistent transformation of this multi-granularity uncertain language information.Secondly,the group evaluation vector is obtained by using the extended weighted average operator of uncertainty,and then the weight vector of each key index is obtained by using the decision theory of uncertain language.Finally,an example is given to verify the practicability and effectiveness of the proposed method.展开更多
Reader proteins that bind specific methyllysine are important to biological functions of lysine methylation,but readers of many methyllysine sites are still unknown.Therefore,development of covalent probes is importan...Reader proteins that bind specific methyllysine are important to biological functions of lysine methylation,but readers of many methyllysine sites are still unknown.Therefore,development of covalent probes is important to identify readers from cell samples so as to understand biological roles of lysine methylation.Generally,readers bind methyllysine via aromatic cages that contain tryptophan,tyrosine and phenylalanine,that offer a unique motif for selective crosslinking.We recently reported a site-selective tryptophan crosslinking strategy based on dimethylsulfonium that mimics dimethyllysine to crosslink tryptophan in aromatic cages of readers.Since tyrosine is a key residue for binding affinity to methyllysine,especially some readers that do not contain tryptophan residues in the binding pocket.Here we developed strategies of site-selective crosslinking to tyrosine.Ultraviolet(UV)source was applied to excite tyrosine at neutral pH or phenoxide at basic p H,and subsequent single-electron transfer(SET)from Tyr*to sulfonium inside the binding pocket enables selective crosslinking.In consequence,methyllysine readers with tyrosine-containing aromatic cages could be selectively crosslinked by site-specific sulfonium peptide probes.In addition,we expanded substrates from aromatic cages to tyrosine residues of proximate contact with sulfonium probes.The pair of LgBiT and SmBiT exhibited orthogonal crosslinking in complicated cell samples.As a result,we may expand sulfonium tools to target local tyrosine in future investigations.展开更多
N6-methyladenosine(m^(6)A)represents the most abundant and functionally significant RNA modification implicated in epigenetic regulation,significantly impacting gene expression through the selective recognition by m^(...N6-methyladenosine(m^(6)A)represents the most abundant and functionally significant RNA modification implicated in epigenetic regulation,significantly impacting gene expression through the selective recognition by m^(6)A reader proteins.Aberrant expression of m^(6)A readers has been associated with cancer progression,contributing to tumor growth,metastasis,drug resistance,and immune evasion.With the increasing research on m^(6)A readers,the discovery of small-molecule inhibitors targeting these proteins has emerged as a promising avenue for cancer therapy.This review delineates the classification and functional roles of m^(6)A readers across various cancers.Furthermore,we summarize and discuss the recent progress in the development of small-molecule inhibitors,with a focus on the medicinal chemistry perspectives.We hope to provide valuable insights to guide future efforts in drug discovery and rational design targeting m^(6)A readers for innovative cancer therapeutics.展开更多
In the context of the continuous deepening of the“Double Reduction”policy and the growing demand for quality education,leveled mathematics readers,as an emerging form of publishing that integrates subject education ...In the context of the continuous deepening of the“Double Reduction”policy and the growing demand for quality education,leveled mathematics readers,as an emerging form of publishing that integrates subject education and reading experience,face challenges such as unclear leveling logic,insufficient functional support,and weak user engagement.This paper introduces the 4V marketing theory and constructs an analytical framework from four dimensions:differentiation,functionality,added value,and resonance.Two representative products,“Climbing Mathematics”and“Spark Mathematics,”are selected for a typical case comparison to identify their strengths and weaknesses in content design,service systems,and brand operation,and to extract transferable strategic elements.The study finds that the user-value-oriented strategy based on the 4V model can effectively address the core issues in the market promotion and user relationship building of leveled mathematics readers,providing practical paths and theoretical support for educational publishing institutions to achieve product innovation and brand upgrading in this niche field.展开更多
A quadrature mixer with a shared transconductor stage is analyzed,including voltage conversion gain, linearity, noise figure, and image rejection. The analysis indicates it has better performance than a conventional G...A quadrature mixer with a shared transconductor stage is analyzed,including voltage conversion gain, linearity, noise figure, and image rejection. The analysis indicates it has better performance than a conventional Gilbert mixer pair in commutating mode. A quadrature down-conversion mixer based on this topology is designed and optimized for an ultra high frequency RFID reader. Operating in the 915MHz ISM band, the presented quadrature mixer measures a conversion gain of 12.5dB,an IIP3 of 10dBm, an IIP2 of 58dBm, and an SSB noise figure of 17.6riB. The chip was fabricated in a 0. 18μm 1P6M RF CMOS process and consumes only 3mA of current from a 1.8V power supply.展开更多
A direct conversion receiver with optimized tolerance to local carrier interference is designed and implemented in a 0.18μm 1P6M mixed-signal CMOS process for a 900MHz RFID reader transceiver. A baseband amplifier wi...A direct conversion receiver with optimized tolerance to local carrier interference is designed and implemented in a 0.18μm 1P6M mixed-signal CMOS process for a 900MHz RFID reader transceiver. A baseband amplifier with series feedback topology is proposed to achieve passive mixer buffering,baseband DC cancellation,and signal amplification simultaneously. The receiver has a measured input ldB compression point of - 4dBm and a sensitivity of - 70dBm when 10dB SNR for digital demodulation is required. The receiver is integrated in a reader transceiver chip and consumes 90mA from a 1.8V supply.展开更多
基金National Natural Science Foundation of China(11971211,12171388).
文摘Complex network models are frequently employed for simulating and studyingdiverse real-world complex systems.Among these models,scale-free networks typically exhibit greater fragility to malicious attacks.Consequently,enhancing the robustness of scale-free networks has become a pressing issue.To address this problem,this paper proposes a Multi-Granularity Integration Algorithm(MGIA),which aims to improve the robustness of scale-free networks while keeping the initial degree of each node unchanged,ensuring network connectivity and avoiding the generation of multiple edges.The algorithm generates a multi-granularity structure from the initial network to be optimized,then uses different optimization strategies to optimize the networks at various granular layers in this structure,and finally realizes the information exchange between different granular layers,thereby further enhancing the optimization effect.We propose new network refresh,crossover,and mutation operators to ensure that the optimized network satisfies the given constraints.Meanwhile,we propose new network similarity and network dissimilarity evaluation metrics to improve the effectiveness of the optimization operators in the algorithm.In the experiments,the MGIA enhances the robustness of the scale-free network by 67.6%.This improvement is approximately 17.2%higher than the optimization effects achieved by eight currently existing complex network robustness optimization algorithms.
基金Projects(41074010,41171343)supported by the National Natural Science Foundation of ChinaProject(BK20140185)supported by Jiangsu Province Natural Science Foundation for Youths,China+1 种基金Project(51204185)supported by National Youth Science Foundation of ChinaProject(2014QNA44)supported by Youth Science Fund of China University of Mining and Technology
文摘The multi-granularity spatial-temporal-related access control（MSTAC） model was proposed to meet the spatial access control requirements for the service-oriented spatial data infrastructure（SDI）. MSTAC extends the attribute constraints of role-based access control（RBAC）, which includes the user＇s location attribute, the role＇s time constraint, the layer vector constraint of a map class, the scale and time constraints of a geographic layer, the topological constraints of geographic features, the semantic attribute expression constraints of geographic features, and the field constraint of feature views. Through this model, authorized users would be limited to access different granularity spatial datasets, such as the map granularity, the graphic layer granularity, the feature object granularity and the feature view granularity. Finally, the MSTAC model is achieved in a web GIS, which shows the positive and negative authorizations to different services in different data granularities and time periods.
基金supported in part by the National Natural Science Foundation of China under Grant 62177029,62307025in part by the Startup Foundation for Introducing Talent of Nanjing University of Posts and Communications under Grant NY221041in part by the General Project of The Natural Science Foundation of Jiangsu Higher Education Institution of China 22KJB520025,23KJD580.
文摘Visible-infrared Cross-modality Person Re-identification(VI-ReID)is a critical technology in smart public facilities such as cities,campuses and libraries.It aims to match pedestrians in visible light and infrared images for video surveillance,which poses a challenge in exploring cross-modal shared information accurately and efficiently.Therefore,multi-granularity feature learning methods have been applied in VI-ReID to extract potential multi-granularity semantic information related to pedestrian body structure attributes.However,existing research mainly uses traditional dual-stream fusion networks and overlooks the core of cross-modal learning networks,the fusion module.This paper introduces a novel network called the Augmented Deep Multi-Granularity Pose-Aware Feature Fusion Network(ADMPFF-Net),incorporating the Multi-Granularity Pose-Aware Feature Fusion(MPFF)module to generate discriminative representations.MPFF efficiently explores and learns global and local features with multi-level semantic information by inserting disentangling and duplicating blocks into the fusion module of the backbone network.ADMPFF-Net also provides a new perspective for designing multi-granularity learning networks.By incorporating the multi-granularity feature disentanglement(mGFD)and posture information segmentation(pIS)strategies,it extracts more representative features concerning body structure information.The Local Information Enhancement(LIE)module augments high-performance features in VI-ReID,and the multi-granularity joint loss supervises model training for objective feature learning.Experimental results on two public datasets show that ADMPFF-Net efficiently constructs pedestrian feature representations and enhances the accuracy of VI-ReID.
基金National Key Research and Development Program of China,No.2016YFB0502300。
文摘Coronavirus disease 2019(COVID-19)is continuing to spread globally and still poses a great threat to human health.Since its outbreak,it has had catastrophic effects on human society.A visual method of analyzing COVID-19 case information using spatio-temporal objects with multi-granularity is proposed based on the officially provided case information.This analysis reveals the spread of the epidemic,from the perspective of spatio-temporal objects,to provide references for related research and the formulation of epidemic prevention and control measures.The case information is abstracted,descripted,represented,and analyzed in the form of spatio-temporal objects through the construction of spatio-temporal case objects,multi-level visual expressions,and spatial correlation analysis.The rationality of the method is verified through visualization scenarios of case information statistics for China,Henan cases,and cases related to Shulan.The results show that the proposed method is helpful in the research and judgment of the development trend of the epidemic,the discovery of the transmission law,and the spatial traceability of the cases.It has a good portability and good expansion performance,so it can be used for the visual analysis of case information for other regions and can help users quickly discover the potential knowledge this information contains.
基金funded by the Fujian Province Science and Technology Plan,China(Grant Number 2019H0017).
文摘Accurate forecasting of time series is crucial across various domains.Many prediction tasks rely on effectively segmenting,matching,and time series data alignment.For instance,regardless of time series with the same granularity,segmenting them into different granularity events can effectively mitigate the impact of varying time scales on prediction accuracy.However,these events of varying granularity frequently intersect with each other,which may possess unequal durations.Even minor differences can result in significant errors when matching time series with future trends.Besides,directly using matched events but unaligned events as state vectors in machine learning-based prediction models can lead to insufficient prediction accuracy.Therefore,this paper proposes a short-term forecasting method for time series based on a multi-granularity event,MGE-SP(multi-granularity event-based short-termprediction).First,amethodological framework for MGE-SP established guides the implementation steps.The framework consists of three key steps,including multi-granularity event matching based on the LTF(latest time first)strategy,multi-granularity event alignment using a piecewise aggregate approximation based on the compression ratio,and a short-term prediction model based on XGBoost.The data from a nationwide online car-hailing service in China ensures the method’s reliability.The average RMSE(root mean square error)and MAE(mean absolute error)of the proposed method are 3.204 and 2.360,lower than the respective values of 4.056 and 3.101 obtained using theARIMA(autoregressive integratedmoving average)method,as well as the values of 4.278 and 2.994 obtained using k-means-SVR(support vector regression)method.The other experiment is conducted on stock data froma public data set.The proposed method achieved an average RMSE and MAE of 0.836 and 0.696,lower than the respective values of 1.019 and 0.844 obtained using the ARIMA method,as well as the values of 1.350 and 1.172 obtained using the k-means-SVR method.
文摘A novel multi-granularity flexible-grid switching optical-node architecture is proposed in this paper.In our system,the photonic lanterns are used as mode division multiplexing/demultiplexing(MD-Mux/MD-Demux)for selecting mode.The wavelength division multiplexer/demultiplexer(WDMux/WD-Demux)and the fiber bragg gratings(FBGs)are used to select wavelength channels with the various grid.The experimental results show that the transmission bandwidth covers the C+L band,the average transmission loss is-13.4 dB,and the average crosstalk is-30.5 dB.The optical-node architecture is suit for mode division multiplexing(MDM)optical communication system.
基金supported by the National Natural Science Foundation of China(Nos.62002206 and 62202373)the open topic of the Green Development Big Data Decision-Making Key Laboratory(DM202003).
文摘Extracting valuable information frombiomedical texts is one of the current research hotspots of concern to a wide range of scholars.The biomedical corpus contains numerous complex long sentences and overlapping relational triples,making most generalized domain joint modeling methods difficult to apply effectively in this field.For a complex semantic environment in biomedical texts,in this paper,we propose a novel perspective to perform joint entity and relation extraction;existing studies divide the relation triples into several steps or modules.However,the three elements in the relation triples are interdependent and inseparable,so we regard joint extraction as a tripartite classification problem.At the same time,fromthe perspective of triple classification,we design amulti-granularity 2D convolution to refine the word pair table and better utilize the dependencies between biomedical word pairs.Finally,we use a biaffine predictor to assist in predicting the labels of word pairs for relation extraction.Our model(MCTPL)Multi-granularity Convolutional Tokens Pairs of Labeling better utilizes the elements of triples and improves the ability to extract overlapping triples compared to previous approaches.Finally,we evaluated our model on two publicly accessible datasets.The experimental results show that our model’s ability to extract relation triples on the CPI dataset improves the F1 score by 2.34%compared to the current optimal model.On the DDI dataset,the F1 value improves the F1 value by 1.68%compared to the current optimal model.Our model achieved state-of-the-art performance compared to other baseline models in biomedical text entity relation extraction.
文摘This paper introduces a multi-granularity locking model (MGL) for concurrency control in object-oriented database system briefiy, and presents a MGL model formally. Four lockingscheduling algorithms for MGL are proposed in the paper. The ideas of single queue scheduling(SQS) and dual queue scheduling (DQS) are proposed and the algorithm and the performance evaluation for these two scheduling are presented in some paper. This paper describes a new idea of thescheduling for MGL, compatible requests first (CRF). Combining the new idea with SQS and DQS,we propose two new scheduling algorithms called CRFS and CRFD. After describing the simulationmodel, this paper illustrates the comparisons of the performance among these four algorithms. Asshown in the experiments, DQS has better performance than SQS, CRFD is better than DQS, CRFSperforms better than SQS, and CRFS is the best one of these four scheduling algorithms.
基金the National Natural Science Foundation of China(No.61876144)the Strategy Priority Research Program of Chinese Acade-my of Sciences(No.XDC02070600).
文摘The research on named entity recognition for label-few domain is becoming increasingly important.In this paper,a novel algorithm,positive unlabeled named entity recognition(PUNER)with multi-granularity language information,is proposed,which combines positive unlabeled(PU)learning and deep learning to obtain the multi-granularity language information from a few labeled in-stances and many unlabeled instances to recognize named entities.First,PUNER selects reliable negative instances from unlabeled datasets,uses positive instances and a corresponding number of negative instances to train the PU learning classifier,and iterates continuously to label all unlabeled instances.Second,a neural network-based architecture to implement the PU learning classifier is used,and comprehensive text semantics through multi-granular language information are obtained,which helps the classifier correctly recognize named entities.Performance tests of the PUNER are carried out on three multilingual NER datasets,which are CoNLL2003,CoNLL 2002 and SIGHAN Bakeoff 2006.Experimental results demonstrate the effectiveness of the proposed PUNER.
文摘The two universes multi-granularity fuzzy rough set model is an effective tool for handling uncertainty problems between two domains with the help of binary fuzzy relations. This article applies the idea of neighborhood rough sets to two universes multi-granularity fuzzy rough sets, and discusses the two-universes multi-granularity neighborhood fuzzy rough set model. Firstly, the upper and lower approximation operators are defined in the two universes multi-granularity neighborhood fuzzy rough set model. Secondly, the properties of the upper and lower approximation operators are discussed. Finally, the properties of the two universes multi-granularity neighborhood fuzzy rough set model are verified through case studies.
文摘To effectively deal with fuzzy and uncertain information in public engineering emergencies,an emergency decision-making method based on multi-granularity language information is proposed.Firstly,decision makers select the appropriate language phrase set according to their own situation,give the preference information of the weight of each key indicator,and then transform the multi-granularity language information through consistency.On this basis,the sequential optimization technology of the approximately ideal scheme is introduced to obtain the weight coefficient of each key indicator.Subsequently,the weighted average operator is used to aggregate the preference information of each alternative scheme with the relative importance of decision-makers and the weight of key indicators in sequence,and the comprehensive evaluation value of each scheme is obtained to determine the optimal scheme.Lastly,the effectiveness and practicability of the method are verified by taking the earthwork collapse accident in the construction of a reservoir as an example.
文摘In view of the complexity of emergencies and the subjectivity of decision-makers,a method of determining key emergency indicators based on multi-granularity uncertainty language is proposed.Firstly,decision members use preferred uncertain language phrases to represent the importance of each key indicator and use transformation functions to carry out the consistent transformation of this multi-granularity uncertain language information.Secondly,the group evaluation vector is obtained by using the extended weighted average operator of uncertainty,and then the weight vector of each key index is obtained by using the decision theory of uncertain language.Finally,an example is given to verify the practicability and effectiveness of the proposed method.
基金the support from National Natural Science Foundation of China(No.22161132006)Key R&D Program of Zhejiang(No.2024SSYS0036)Westlake University Startup。
文摘Reader proteins that bind specific methyllysine are important to biological functions of lysine methylation,but readers of many methyllysine sites are still unknown.Therefore,development of covalent probes is important to identify readers from cell samples so as to understand biological roles of lysine methylation.Generally,readers bind methyllysine via aromatic cages that contain tryptophan,tyrosine and phenylalanine,that offer a unique motif for selective crosslinking.We recently reported a site-selective tryptophan crosslinking strategy based on dimethylsulfonium that mimics dimethyllysine to crosslink tryptophan in aromatic cages of readers.Since tyrosine is a key residue for binding affinity to methyllysine,especially some readers that do not contain tryptophan residues in the binding pocket.Here we developed strategies of site-selective crosslinking to tyrosine.Ultraviolet(UV)source was applied to excite tyrosine at neutral pH or phenoxide at basic p H,and subsequent single-electron transfer(SET)from Tyr*to sulfonium inside the binding pocket enables selective crosslinking.In consequence,methyllysine readers with tyrosine-containing aromatic cages could be selectively crosslinked by site-specific sulfonium peptide probes.In addition,we expanded substrates from aromatic cages to tyrosine residues of proximate contact with sulfonium probes.The pair of LgBiT and SmBiT exhibited orthogonal crosslinking in complicated cell samples.As a result,we may expand sulfonium tools to target local tyrosine in future investigations.
基金supported by the National Natural Science Foundation of China(82173680 and 82373741)the Fundamental Research Funds for the Central Universities(2632025TD01,China)+2 种基金the Basic Research Program of Jiangsu for Distinguished Young Scientists(grant BK20220087,China)the China Postdoctoral Science Foundation(2023M743900)the Basic Research Program of Jiangsu(grant BK20241588,China).
文摘N6-methyladenosine(m^(6)A)represents the most abundant and functionally significant RNA modification implicated in epigenetic regulation,significantly impacting gene expression through the selective recognition by m^(6)A reader proteins.Aberrant expression of m^(6)A readers has been associated with cancer progression,contributing to tumor growth,metastasis,drug resistance,and immune evasion.With the increasing research on m^(6)A readers,the discovery of small-molecule inhibitors targeting these proteins has emerged as a promising avenue for cancer therapy.This review delineates the classification and functional roles of m^(6)A readers across various cancers.Furthermore,we summarize and discuss the recent progress in the development of small-molecule inhibitors,with a focus on the medicinal chemistry perspectives.We hope to provide valuable insights to guide future efforts in drug discovery and rational design targeting m^(6)A readers for innovative cancer therapeutics.
文摘In the context of the continuous deepening of the“Double Reduction”policy and the growing demand for quality education,leveled mathematics readers,as an emerging form of publishing that integrates subject education and reading experience,face challenges such as unclear leveling logic,insufficient functional support,and weak user engagement.This paper introduces the 4V marketing theory and constructs an analytical framework from four dimensions:differentiation,functionality,added value,and resonance.Two representative products,“Climbing Mathematics”and“Spark Mathematics,”are selected for a typical case comparison to identify their strengths and weaknesses in content design,service systems,and brand operation,and to extract transferable strategic elements.The study finds that the user-value-oriented strategy based on the 4V model can effectively address the core issues in the market promotion and user relationship building of leveled mathematics readers,providing practical paths and theoretical support for educational publishing institutions to achieve product innovation and brand upgrading in this niche field.
文摘A quadrature mixer with a shared transconductor stage is analyzed,including voltage conversion gain, linearity, noise figure, and image rejection. The analysis indicates it has better performance than a conventional Gilbert mixer pair in commutating mode. A quadrature down-conversion mixer based on this topology is designed and optimized for an ultra high frequency RFID reader. Operating in the 915MHz ISM band, the presented quadrature mixer measures a conversion gain of 12.5dB,an IIP3 of 10dBm, an IIP2 of 58dBm, and an SSB noise figure of 17.6riB. The chip was fabricated in a 0. 18μm 1P6M RF CMOS process and consumes only 3mA of current from a 1.8V power supply.
基金the Science and Technology Commission of Shanghai Municipality(No.057062010)the EU BRIDGE Project(No.033546)~~
文摘A direct conversion receiver with optimized tolerance to local carrier interference is designed and implemented in a 0.18μm 1P6M mixed-signal CMOS process for a 900MHz RFID reader transceiver. A baseband amplifier with series feedback topology is proposed to achieve passive mixer buffering,baseband DC cancellation,and signal amplification simultaneously. The receiver has a measured input ldB compression point of - 4dBm and a sensitivity of - 70dBm when 10dB SNR for digital demodulation is required. The receiver is integrated in a reader transceiver chip and consumes 90mA from a 1.8V supply.
