期刊文献+
共找到415篇文章
< 1 2 21 >
每页显示 20 50 100
Theoretical Modeling and Compensation of Errors in Industrial Robot Accuracy and Repeatability
1
作者 Zhou Yang 《机械工程与设计(中英文版)》 2025年第2期14-17,共4页
Industrial robots are integral to modern manufacturing systems,enabling high precision,high throughput,and flexibility.However,errors in accuracy and repeatability,which arise from a variety of sources such as mechani... Industrial robots are integral to modern manufacturing systems,enabling high precision,high throughput,and flexibility.However,errors in accuracy and repeatability,which arise from a variety of sources such as mechanical wear,calibration issues,and environmental factors,can significantly impact the performance of industrial robots.This paper aims to explore the theoretical modeling of errors in industrial robot systems and propose compensation strategies to enhance their accuracy and repeatability.Key factors contributing to errors,such as kinematic,dynamic,and environmental influences,are discussed in detail.Additionally,the paper explores various compensation techniques,including geometric error compensation,dynamic compensation,and adaptive control approaches.Through the integration of error modeling and compensation methods,industrial robots can achieve improved performance,ensuring higher operational efficiency and product quality.The paper concludes by highlighting the challenges and future research directions for improving the accuracy and repeatability of industrial robots in practical applications. 展开更多
关键词 Industrial Robots ACCURACY repeatability Error modeling Compensation Strategies Kinematic Errors Dynamic Errors Adaptive Control
在线阅读 下载PDF
Viscoelastic model for asphalt mixture under repeated haversine load 被引量:1
2
作者 张久鹏 黄晓明 《Journal of Southeast University(English Edition)》 EI CAS 2009年第4期523-526,共4页
The series-wound dashpot of the Burgers model is modified by introducing the strain hardening parameter, and the new model is considered as a combination of the modified dashpot and the Van Der Poel model. The cyclica... The series-wound dashpot of the Burgers model is modified by introducing the strain hardening parameter, and the new model is considered as a combination of the modified dashpot and the Van Der Poel model. The cyclical pulse load consisting of a haversine load time and a rest period is adopted to simulate the actual vehicle load, and the permanent strain model under the repeated load is derived from the rheological and viscoelastic theories. Subsequently, the model is validated by the results of uniaxial repeated load permanent deformation tests of three asphalt mixtures. It is indicated that the proportion of residual viscoelastic strain to permanent strain decreases gradually with the load cycles, and only accounts for 2% to 3% during most of the loading period. If the rest period is long, the residual viscoelastic strain is little. The rest period of the actual vehicle load may be long enough, so the residual viscoelasticity can be ignored and the simplified model can be obtained. The proposed model can well describe the permanent deformation of asphalt mixtures under repeated load. 展开更多
关键词 asphalt mixture permanent deformation mechanics model repeated haversine load
在线阅读 下载PDF
Modeling diseases of noncoding unstable repeat expansions using mutant pluripotent stem cells 被引量:2
3
作者 Shira Yanovsky-Dagan Hagar Mor-Shaked Rachel Eiges 《World Journal of Stem Cells》 SCIE CAS 2015年第5期823-838,共16页
Pathogenic mutations involving DNA repeat expansions are responsible for over 20 different neuronal and neuromuscular diseases. All result from expanded tracts of repetitive DNA sequences(mostly microsatellites) that ... Pathogenic mutations involving DNA repeat expansions are responsible for over 20 different neuronal and neuromuscular diseases. All result from expanded tracts of repetitive DNA sequences(mostly microsatellites) that become unstable beyond a critical length whentransmitted across generations. Nearly all are inherited as autosomal dominant conditions and are typically associated with anticipation. Pathologic unstable repeat expansions can be classified according to their length, repeat sequence, gene location and underlying pathologic mechanisms. This review summarizes the current contribution of mutant pluripotent stem cells(diseased human embryonic stem cells and patient-derived induced pluripotent stem cells) to the research of unstable repeat pathologies by focusing on particularly large unstable noncoding expansions. Among this class of disorders are Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome, myotonic dystrophy type 1 and myotonic dystrophy type 2, Friedreich ataxia and C9 related amyotrophic lateral sclerosis and/or frontotemporal dementia, Facioscapulohumeral Muscular Dystrophy and potentially more. Common features that are typical to this subclass of conditions are RNA toxic gain-of-function, epigenetic loss-of-function, toxic repeat-associated non-ATG translation and somatic instability. For each mechanism we summarize the currently available stem cell based models, highlight how they contributed to better understanding of the related mechanism, and discuss how they may be utilized in future investigations. 展开更多
关键词 UNSTABLE repeat ASSOCIATED disorders Human embryonic STEM CELLS Patient-derived inducedpluripotent STEM CELLS Disease modelING Epigenetics repeat-associated non-ATG translation RNA toxicity repeat somatic instability
暂未订购
Effect of Tire Repeated Root Modal on Tire Modelling with Experimental Modal
4
作者 Zhenfeng Wang Yongchang Du +1 位作者 Mingming Dong Liang Gu 《Journal of Beijing Institute of Technology》 EI CAS 2017年第1期67-74,共8页
The effect of tire repeated root modal(RRM)on tire modeling with an experimental modal is studied.Firstly,a radial tire with radial and tangential RRMs is tested and analyzed.By multi-point exciting of the radial ti... The effect of tire repeated root modal(RRM)on tire modeling with an experimental modal is studied.Firstly,a radial tire with radial and tangential RRMs is tested and analyzed.By multi-point exciting of the radial tire,a multiple reference frequency domain method based on a least squares(LMS PolyMAX)algorithm is used to identify modal parameters.Then,modal stability diagram(MSD),modal indication function(MIF)and modal assurance criteria(Auto-MAC)matrix are utilized to induce multiple inputs multiple outputs(MIMO)frequency response function(FRF)matrixes.The tests reveal that notable repeated roots exist in both radial and tangential response modes.Their modal frequencies and damping factors are approximately the same,the amplitudes of modal vectors are in the same order of magnitude,and the mode shapes are orthogonal.Based on the works mentioned,the method of trigonometric series modal shapes fitting is adopted,the effects of RRM model on tire modeling with a vertical experimental modal are discussed.The final results show that the effects of considering the RRM shapes are equivalent to the tire mode shapes depended on rotating the tire’s different exciting points during tire modeling,and since considering the RRM,the tire mode shapes can be unified and fixed during tire modeling. 展开更多
关键词 modal test repeated root modal ploy MAX method tire model
在线阅读 下载PDF
Elastic Predictions of 3D Orthogonal Woven Composites Using Micro/meso-scale Repeated Unit Cell Models
5
作者 JIA Xiwen GAO Limin +2 位作者 ZHANG Tian ZHANG Fa WANG Yan 《Journal of Donghua University(English Edition)》 EI CAS 2019年第4期390-398,共9页
This presentation predicts the elastic properties of three-dimensional(3D)orthogonal woven composite(3DOWC)by finite element analysis based on micro/meso repeated unit cell(RUC)models.First,the properties of fiber yar... This presentation predicts the elastic properties of three-dimensional(3D)orthogonal woven composite(3DOWC)by finite element analysis based on micro/meso repeated unit cell(RUC)models.First,the properties of fiber yarn are obtained by analysis on a micro-scale RUC model assuming fibers in a hexagonal distribution pattern in the polymer matrix.Then a full thickness meso-scale RUC model including weft yarns,warp yarns,Z-yarns and pure resin zones is established and full stiffness matrix of the 3DOWC including the in-plane and flexural constants are predicted.For thick 3DOWC with large number of weft,warp layers,an alternative analysis method is proposed in which an inner meso-RUC and a surface meso-RUC are established,respectively.Then the properties of 3DOWC are deduced based on laminate theory and properties of the inner and surface layers.The predicted results by the above two alternative methods are in good experimental agreement. 展开更多
关键词 composite MULTI-SCALE analysis repeated unit cell model FINITE ELEMENT method
在线阅读 下载PDF
A Novel Dynamic Decision Model in 2-player Symmetric Repeated Games
6
作者 Liu Weibing Wang Xianjia Wang Guangmin 《Engineering Sciences》 EI 2008年第1期43-46,共4页
Considering the dynamic character of repeated games and Markov process, this paper presented a novel dynamic decision model for symmetric repeated games. In this model, players' actions were mapped to a Markov decisi... Considering the dynamic character of repeated games and Markov process, this paper presented a novel dynamic decision model for symmetric repeated games. In this model, players' actions were mapped to a Markov decision process with payoffs, and the Boltzmann distribution was intousluced. Our dynamic model is different from others' , we used this dynamic model to study the iterated prisoner' s dilemma, and the results show that this decision model can successfully be used in symmetric repeated games and has an ability of adaptive learning. 展开更多
关键词 game theory evolutionary game repeated game Markov process decision model
在线阅读 下载PDF
Long-term floor heave analysis of loess tunnel based on modified Green-Ampt infiltration model
7
作者 CHANG Zhou YAN Changgen +2 位作者 YIN Peijie LAN Hengxing BAO Han 《Journal of Mountain Science》 2025年第12期4574-4594,共21页
Floor heave is a common water-induced issue of loess tunnels.However,the mechanism of tunnel floor heave induced by repeated rainfall or irrigation remains poorly understood.This study analyzes moisture variation at t... Floor heave is a common water-induced issue of loess tunnels.However,the mechanism of tunnel floor heave induced by repeated rainfall or irrigation remains poorly understood.This study analyzes moisture variation at the tunnel base and invert deformation through a 15-year survey of an operational loess tunnel.An improved Green-Ampt model was developed to capture the effects of interannual repeated infiltration on water content,permeability,and matric suction at the tunnel base.The model was validated using soil column infiltration tests.The calculated wetting front depth was incorporated into the tunnel numerical simulation to analyze the development of floor heave and assess its several influencing factors.Results show the base average water content at the tunnel base increases exponentially with operational years.After 15 years,over 50%of the monitored sections reach saturation,leading to significant invert uplift.Based on the plastic limit,saturation water content,and liquid limit of loess,floor heave is categorized into four levels with deformation thresholds at 10,25,and 50 mm.The modified Green-Ampt model is suitable for repeated infiltration conditions and offers practical guidance.Neglecting hydraulic deterioration due to repeated infiltration may lead to significant prediction errors.Numerical simulations reveal that the inverted arch uplift height,width,and height-to-width ratio increase linearly with the rise in the number of infiltration events.The uplift deformation follows Gaussian distribution in both cross and longitudinal sections,forming aΛ-shaped floor heave.The influence of infiltration duration,water content,horizontal infiltration,asymmetric infiltration,burial depth,and the number of infiltration events enhanced successively on floor heave.This model facilitates the prediction of floor heave under dynamic hydrological conditions during long-term tunnel operation. 展开更多
关键词 Loess tunnel Floor heave Green-Ampt model repeated infiltration Sensitivity analysis Loess Plateau
原文传递
Exploiting a No-Regret Opponent in Repeated Zero-Sum Games
8
作者 LI Kai HUANG Wenhan +1 位作者 LI Chenchen DENG Xiaotie 《Journal of Shanghai Jiaotong university(Science)》 2025年第2期385-398,共14页
In repeated zero-sum games,instead of constantly playing an equilibrium strategy of the stage game,learning to exploit the opponent given historical interactions could typically obtain a higher utility.However,when pl... In repeated zero-sum games,instead of constantly playing an equilibrium strategy of the stage game,learning to exploit the opponent given historical interactions could typically obtain a higher utility.However,when playing against a fully adaptive opponent,one would have dificulty identifying the opponent's adaptive dynamics and further exploiting its potential weakness.In this paper,we study the problem of optimizing against the adaptive opponent who uses no-regret learning.No-regret learning is a classic and widely-used branch of adaptive learning algorithms.We propose a general framework for online modeling no-regret opponents and exploiting their weakness.With this framework,one could approximate the opponent's no-regret learning dynamics and then develop a response plan to obtain a significant profit based on the inferences of the opponent's strategies.We employ two system identification architectures,including the recurrent neural network(RNN)and the nonlinear autoregressive exogenous model,and adopt an efficient greedy response plan within the framework.Theoretically,we prove the approximation capability of our RNN architecture at approximating specific no-regret dynamics.Empirically,we demonstrate that during interactions at a low level of non-stationarity,our architectures could approximate the dynamics with a low error,and the derived policies could exploit the no-regret opponent to obtain a decent utility. 展开更多
关键词 no-regret learning repeated game opponent exploitation opponent modeling dynamical system system identification recurrent neural network(RNN)
原文传递
轻质馏分油运动黏度测量结果的不确定度评定
9
作者 赵丽信 石欣 康徐伟 《当代化工》 2026年第1期31-34,41,共5页
采用玻璃毛细管黏度计,针对轻质馏分油在40℃下的运动黏度进行了测量。为了更准确地评估测量结果的可靠性,建立了相应的测量模型,深入分析了不确定度的主要来源及其影响因素。根据标准《测量不确定度的评定与表示》(JJF 1059.1—2012),... 采用玻璃毛细管黏度计,针对轻质馏分油在40℃下的运动黏度进行了测量。为了更准确地评估测量结果的可靠性,建立了相应的测量模型,深入分析了不确定度的主要来源及其影响因素。根据标准《测量不确定度的评定与表示》(JJF 1059.1—2012),量化了各个不确定度分量,并合成了测试结果的相对标准不确定度。最终,计算出了相对扩展不确定度,并给出了相应的评定结果。结果表明:测量重复性和玻璃毛细管黏度计常数是影响轻质馏分油在40℃下运动黏度测量结果不确定度的主要因素。经计算,轻质馏分油运动黏度(40℃)测定结果的扩展不确定度为U=0.082(k=2)。 展开更多
关键词 不确定度 轻质馏分油 运动黏度 测量 重复性 黏度 模型 实验验证
在线阅读 下载PDF
Quantum Homomorphic Signature with Repeatable Verification 被引量:2
10
作者 Tao Shang Zhuang Pei +1 位作者 Ranyiliu Chen Jianwei Liu 《Computers, Materials & Continua》 SCIE EI 2019年第4期149-165,共17页
In January 2015,the first quantum homomorphic signature scheme was proposed creatively.However,only one verifier is allowed to verify a signature once in this scheme.In order to support repeatable verification for gen... In January 2015,the first quantum homomorphic signature scheme was proposed creatively.However,only one verifier is allowed to verify a signature once in this scheme.In order to support repeatable verification for general scenario,we propose a new quantum homomorphic signature scheme with repeatable verification by introducing serial verification model and parallel verification model.Serial verification model solves the problem of signature verification by combining key distribution and Bell measurement.Parallel verification model solves the problem of signature duplication by logically treating one particle of an EPR pair as a quantum signature and physically preparing a new EPR pair.These models will be beneficial to the signature verification of general scenarios.Scheme analysis shows that both intermediate verifiers and terminal verifiers can successfully verify signatures in the same operation with fewer resource consumption,and especially the verified signature in entangled states can be used repeatedly. 展开更多
关键词 Quantum homomorphic signature repeatable verification serial model parallel model bell measurement
在线阅读 下载PDF
Experimental study on repeatedly loaded foundation soil strengthened by wraparound geosynthetic reinforcement technique 被引量:3
11
作者 Muhammad Nouman Amjad Raja Sanjay Kumar Shukla 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2021年第4期899-911,共13页
In the recent past,the potential benefits of wraparound geosynthetic reinforcement technique for constructing the reinforced soil foundations have been reported.This paper presents the experimental study on the behavi... In the recent past,the potential benefits of wraparound geosynthetic reinforcement technique for constructing the reinforced soil foundations have been reported.This paper presents the experimental study on the behaviour of model strip footing resting on sandy soil bed reinforced with geosynthetic in wraparound and planar forms under monotonic and repeated loadings.The geosynthetic layers were laid according to the reinforcement ratio to minimise the scale effect.It is found that for the same amount of reinforcement material,the wraparound reinforced model resulted in less settlement in comparison to planar reinforced models.The efficiency of wraparound reinforced model increased with the increase in load amplitude and the rate of total cumulative settlement substantially decreased with the increase in number of load cycles.The wraparound reinforced model has shown about 45% lower average total settlement in comparison to unreinforced model,while the double-layer reinforced model has about 41% lower average total settlement at the cost of approximately twice the material and 1.5 times the occupied land width ratio.Moreover,wraparound models have shown much greater stability in comparison to their counterpart models when subjected to incremental repeated loading. 展开更多
关键词 GEOSYNTHETICS repeated loads Wraparound reinforcement technique model tests Footing settlement Bearing capacity Reinforcement ratio Strip footing
在线阅读 下载PDF
Analytical solutions for Earth discontinuous coverage of satellite constellation with repeating ground tracks 被引量:3
12
作者 Xiangyue HE Haiyang LI 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2022年第10期275-291,共17页
This paper presents an analytical model for calculating the Earth discontinuous coverage of satellite constellation with repeating ground tracks by integrating and extending the application of coverage region and rout... This paper presents an analytical model for calculating the Earth discontinuous coverage of satellite constellation with repeating ground tracks by integrating and extending the application of coverage region and route theory.Specifically,the visibility condition for a ground point is represented as a coverage region in the two-dimension map of visibility properties,and the trajectories of satellites with circular orbits and repeating ground tracks are converted to several inclined lines in the map.By analyzing the intersections of the lines and the edge of the coverage region,the coverage durations for the ground point can be calculated.Based on the point coverage,the variations of coverage characteristics along the parallel are analyzed,and the regional or global coverage characteristics of constellations can be obtained.Numerical examples show that the proposed method can accurately and rapidly calculate the coverage characteristics,e.g.revisit time and coverage time.The calculated results are extremely close to those of the Satellite Tool Kit(STK)and are also superior to the existing research results.The proposed analytical model can be a useful tool for constellation design and coverage performance analysis. 展开更多
关键词 Analytical model Coverage region Earth discontinuous coverage repeating ground track Satellite constellation Two-dimension map of visibility properties
原文传递
Neural network-based model for prediction of permanent deformation of unbound granular materials 被引量:1
13
作者 Ali Alnedawi Riyadh Al-Ameri Kali Prasad Nepal 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2019年第6期1231-1242,共12页
Several available mechanistic-empirical pavement design methods fail to include predictive model for permanent deformation(PD)of unbound granular materials(UGMs),which make these methods more conservative.In addition,... Several available mechanistic-empirical pavement design methods fail to include predictive model for permanent deformation(PD)of unbound granular materials(UGMs),which make these methods more conservative.In addition,there are limited regression models capable of predicting the PD under multistress levels,and these models have regression limitations and generally fail to cover the complexity of UGM behaviour.Recent researches are focused on using new methods of computational intelligence systems to address the problems,such as artificial neural network(ANN).In this context,we aim to develop an artificial neural model to predict the PD of UGMs exposed to repeated loads.Extensive repeated load triaxial tests(RLTTs)were conducted on base and subbase materials locally available in Victoria,Australia to investigate the PD properties of the tested materials and to prepare the database of the neural networks.Specimens were prepared over different moisture contents and gradations to cover a wide testing matrix.The ANN model consists of one input layer with five neurons,one hidden layer with twelve neurons,and one output layer with one neuron.The five inputs were the number of load cycles,deviatoric stress,moisture content,coefficient of uniformity,and coefficient of curvature.The sensitivity analysis showed that the most important indicator that impacts PD is the number of load cycles with influence factor of 41%.It shows that the ANN method is rapid and efficient to predict the PD,which could be implemented in the Austroads pavement design method. 展开更多
关键词 Flexible PAVEMENT design Unbound GRANULAR materials PERMANENT deformation (PD) repeated load TRIAXIAL test (RLTT) PREDICTION models Artificial neural network (ANN)
在线阅读 下载PDF
Influence of Repeated Variable Load on Long-Term Behavior of Concrete Elements 被引量:3
14
作者 Toni Arangjelovski GoranMarkovski Peter Mark 《Journal of Civil Engineering and Architecture》 2014年第3期302-314,共13页
The objective of this paper is to study the influence of repeated variable action on long-term behavior of concrete structural elements using quasi-permanent combination of actions, for the assessment of long-term eff... The objective of this paper is to study the influence of repeated variable action on long-term behavior of concrete structural elements using quasi-permanent combination of actions, for the assessment of long-term effects (e.g., effects due to creep and shrinkage in concrete structures), as it is proposed in Eurocodes. Extensive experimental program and analytical research using model B3 and AAEM (age adjusted effective modulus) method was performed in order to define quasi-permanent factor ψ2, for two specific loading histories. These loading histories were consist of long-term permanent action "G" and repeated variable action "Q". The variable load was applied in cycles of loading/unloading for 24 h and 48 h in period of 400 days appropriately for one series of concrete elements. 24 reinforced concrete beams, dimensions 150 mm × 280 mm × 3,000 mm, were tested. Twelve beams were made of concrete class C30/37 and 12 of concrete class C60/75. 展开更多
关键词 repeated variable actions autogenous shrinkage CREEP model B3.
在线阅读 下载PDF
Similarity evaluation model for the internal defect detection of strip steel 被引量:1
15
作者 ZHANG Yalin WANG Yaojie WANG Xuemin 《Baosteel Technical Research》 CAS 2024年第1期8-13,共6页
An internal defect meter is an instrument to detect the internal inclusion defects of cold-rolled strip steel.The detection accuracy of the equipment can be evaluated based on the similarity of the multiple detection ... An internal defect meter is an instrument to detect the internal inclusion defects of cold-rolled strip steel.The detection accuracy of the equipment can be evaluated based on the similarity of the multiple detection data obtained for the same steel coil.Based on the cosine similarity model and eigenvalue matrix model,a comprehensive evaluation method to calculate the weighted average of similarity is proposed.Results show that the new method is consistent with and can even replace artificial evaluation to realize the automatic evaluation of strip defect detection results. 展开更多
关键词 internal defect INCLUSION similarity evaluation model repeatability detection equipment strip steel
在线阅读 下载PDF
The impact of consumer perceived value on repeat purchase intention based on online reviews: by the method of text mining 被引量:3
16
作者 Ning Zhang Rong Liu +1 位作者 Xiao-Yang Zhang Zhi-Liang Pang 《Data Science and Management》 2021年第3期22-32,共11页
The progress of IT technology such as social network and mobile payment and the change of social economic environment promote the emergence of sharing economy.As a subversive business model,the sharing economy is grow... The progress of IT technology such as social network and mobile payment and the change of social economic environment promote the emergence of sharing economy.As a subversive business model,the sharing economy is growing at an alarming rate all over the world.However,the influencing factors of consumers'continuous participation in the sharing economy are not clear.The paper aims to clarify the relationship between consumer perceived value and repeat purchase intention in the sharing economy.Taking the sharing economy platform(Airbnb)as an example,it proposes a dimension framework of consumer perceived value in peer-to-peer(P2P)accommodation rental service,including functional value,hedonic value,epistemic value and social relationship value.This paper used big data technology to crawl online reviews of P2P accommodation platform.LDA(Latent Dirichlet Allocation)topic model and sentiment analytics method were applied to construct the measurement indicators of perceived value based on online reviews.And repeat purchase intention variables were extracted from online reviews.Then structural equation model was used to examine the effect of perceived value dimensions on it.The paper identified that perceived value has a positive impact on consumers'repurchase intention in P2P accommodation.Also,social relationship value was considered as the most important influencing factor. 展开更多
关键词 Sharing economy Peer-to-peer accommodation repeat purchase intention LDA topic model Sentiment analytics
在线阅读 下载PDF
Establishment of a Tumor-bearing Mouse Model Stably Expressing Human Tumor Antigens Survivin and MUC1 VNTRs
17
作者 ZHANG Li-xing DU Jian-shi +5 位作者 WANG Yu-qian LIU Chen-lu XIA Qiu ZHANG Xi-zhen CONG Xian-ling ZHANG Hai-hong 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2012年第2期259-263,共5页
The eukaryotic vectors VR1012 expressing survivin or 33 tandem repeats of human mucin 1(MUC1)(VNTRs),namely,VR1012-S and VR1012-VNTR(VNTR=variable number of tandem repeat),were constructed by cloning survivin an... The eukaryotic vectors VR1012 expressing survivin or 33 tandem repeats of human mucin 1(MUC1)(VNTRs),namely,VR1012-S and VR1012-VNTR(VNTR=variable number of tandem repeat),were constructed by cloning survivin and VNTR genes into VR1012,respectively.The eukaryotic vector pEGFP expressing survivin and MUC1 VNTRs fusion gene pEGFP-MS was also constructed.Mouse melanoma cell line(B16) stably expressing survivin and MUC1 VNTRs(MS + B16) was established by Lipofectamine-mediated transfection of pEGFP-MS into B16 cells.EGFP expression in MS + B16 cells was observed using a fluorescent microscope and survivin and MUC1 VNTRs(MS) expression was confirmed by means of Western blot analysis.A syngenic graft tumor model was generated by subcutaneous injection of MS + B16 cells into C57/BL6 mice and tumor size increased rapidly with time in a cell number dependent manner.After the third immunization,mice were challenged subcutaneously with 5×l0 5 MS + B16 cells.Compared with that of the negative control immunized with phosphate-buffered saline(PBS),a significant reduction of tumor growth was observed in groups immunized with survivin plasmid DNA and MUC1 VNTRs plasmid DNA.Thus,the suppression of subcutaneous tumor was antigen-specific.This model is useful for the development of tumor vaccines targeting survivin and MUCI VNTRs. 展开更多
关键词 SURVIVIN MUC1 variable-number tandem repeat(MUC1 VNTR) Tumor antigen Tumor model Tumor vaccine
在线阅读 下载PDF
Parameter Estimation in Logistic Regression for Transition, Reverse Transition and Repeated Transition from Repeated Outcomes
18
作者 Rafiqul I. Chowdhury M. Ataharul Islam +1 位作者 Shahariar Huda Laurent Briollais 《Applied Mathematics》 2012年第11期1739-1749,共11页
Covariate dependent Markov models dealing with estimation of transition probabilities for higher orders appear to be restricted because of over-parameterization. An improvement of the previous methods for handling run... Covariate dependent Markov models dealing with estimation of transition probabilities for higher orders appear to be restricted because of over-parameterization. An improvement of the previous methods for handling runs of events by expressing the conditional probabilities in terms of the transition probabilities generated from Markovian assumptions was proposed using Chapman-Kolmogorov equations. Parameter estimation of that model needs extensive pre-processing and computations to prepare data before using available statistical softwares. A computer program developed using SAS/IML to estimate parameters of the model are demonstrated, with application to Health and Retirement Survey (HRS) data from USA. 展开更多
关键词 COMPUTER PROGRAM MARKOV model TRANSITION REVERSE TRANSITION repeated TRANSITION
暂未订购
农机数字化大数据管理平台的设计——基于电子商务平台重复客户预测模型 被引量:2
19
作者 张璐 《农机化研究》 北大核心 2025年第4期127-131,共5页
随着信息技术和农机现代化的加速推进,数字化农机管理已成为当今农业发展的重要趋势。为此,基于电子商务平台重复客户预测模型,提出了一种基于Hadoop和物联网的农机数字化大数据管理平台,旨在将传统农业生产与信息技术有机结合,实现农... 随着信息技术和农机现代化的加速推进,数字化农机管理已成为当今农业发展的重要趋势。为此,基于电子商务平台重复客户预测模型,提出了一种基于Hadoop和物联网的农机数字化大数据管理平台,旨在将传统农业生产与信息技术有机结合,实现农机作业数据的实时监测、质量分析、预测与预警、决策支持等功能,为农机作业的自动化和精准化提供有力保障。 展开更多
关键词 数字化农机 大数据 电子商务 预测模型 HADOOP 重复客户
在线阅读 下载PDF
上一页 1 2 21 下一页 到第
使用帮助 返回顶部