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Multi-dimensional optimization of polymer-involved Li^(+)solvation enabling stable polymer plastic crystal electrolyte for long-cycle lithium metal batteries
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作者 Lianzhan Huang Yuanlong Wu +6 位作者 Piao Luo Kexin Su Xin Song Mingdong Liu Minjian Li Huiyu Song Zhiming Cui 《Journal of Energy Chemistry》 2026年第1期656-665,I0015,共11页
Succinonitrile(SN)-based polymer plastic crystal electrolytes(PPCEs)are regarded as promising candidates for lithium metal batteries but suffer from serious side reactions with Li metal.Herein,we propose a multi-dimen... Succinonitrile(SN)-based polymer plastic crystal electrolytes(PPCEs)are regarded as promising candidates for lithium metal batteries but suffer from serious side reactions with Li metal.Herein,we propose a multi-dimensional optimization strategy to alleviate the side reactions between SN and Li metal,and develop a highly stable poly-vinylethylene carbonate-based PPCE(PPCE-VEC).Moreover,we identify the intrinsic factors of multi-dimensional polymer structures on the electrolyte stability by three typical classes of polyesters.The PPCE-VEC constructed by in situ polymerization exhibits much better stability than poly-vinylene carbonate-based PPCE(PPCE-VCA)and poly-trifluoroethyl acrylate-based PPCE(PPCE-TFA),which is verified by its fewer SN-decomposition species in X-ray photoelectron spectroscopy(XPS)and outstanding full cell performance.The PPCE-VEC-enabled LiNi_(0.6)Co_(0.2)Mn_(0.2)O_(2)full cell achieve 73.7%capacity retention after 1400 cycles,which outperforms PPCE-VCA-and PPCE-TFA-enabled full cells(61.9%and 46.9%).Spectral analysis and theoretical calculation reveal that the high solvation ability of the carbonyl site,flexible polymer chain,and homogeneous electrolyte phase of PPCE-VEC are favorable to maximizing competition coordination with Li^(+)to weaken the Li^(+)–SN binding and shape an anion-rich solvation structure.This optimized polymer-involved Li^(+)solvation enhances SN stability and facilitates the formation of B/F enriched solid-electrolyte interphase(SEI),thus significantly improving PPCE stability. 展开更多
关键词 SUCCINONITRILE Li metal Polymer plastic crystal electrolytes multi-dimensional polymer structures
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Composite anti-disturbance predictive control of unmanned systems with time-delay using multi-dimensional Taylor network 被引量:1
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作者 Chenlong LI Wenshuo LI Zejun ZHANG 《Chinese Journal of Aeronautics》 2025年第7期589-600,共12页
A composite anti-disturbance predictive control strategy employing a Multi-dimensional Taylor Network(MTN)is presented for unmanned systems subject to time-delay and multi-source disturbances.First,the multi-source di... A composite anti-disturbance predictive control strategy employing a Multi-dimensional Taylor Network(MTN)is presented for unmanned systems subject to time-delay and multi-source disturbances.First,the multi-source disturbances are addressed according to their specific characteristics as follows:(A)an MTN data-driven model,which is used for uncertainty description,is designed accompanied with the mechanism model to represent the unmanned systems;(B)an adaptive MTN filter is used to remove the influence of the internal disturbance;(C)an MTN disturbance observer is constructed to estimate and compensate for the influence of the external disturbance;(D)the Extended Kalman Filter(EKF)algorithm is utilized as the learning mechanism for MTNs.Second,to address the time-delay effect,a recursiveτstep-ahead MTN predictive model is designed utilizing recursive technology,aiming to mitigate the impact of time-delay,and the EKF algorithm is employed as its learning mechanism.Then,the MTN predictive control law is designed based on the quadratic performance index.By implementing the proposed composite controller to unmanned systems,simultaneous feedforward compensation and feedback suppression to the multi-source disturbances are conducted.Finally,the convergence of the MTN and the stability of the closed-loop system are established utilizing the Lyapunov theorem.Two exemplary applications of unmanned systems involving unmanned vehicle and rigid spacecraft are presented to validate the effectiveness of the proposed approach. 展开更多
关键词 multi-dimensional Taylor network Composite anti-disturbance Predictive control Unmanned systems Multi-source disturbances TIME-DELAY
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Retraced Multi-dimensional Chinese Logic System behind Chinese Medicine
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作者 Edwin C.L.Yu 《Chinese Medicine and Culture》 2025年第1期1-12,共12页
The ancient tacit knowledge behind the logic system permeated the culture and promoted numerous impactful inventions throughout the history. Traditional Chinese medicine with its effectiveness should also have stemmed... The ancient tacit knowledge behind the logic system permeated the culture and promoted numerous impactful inventions throughout the history. Traditional Chinese medicine with its effectiveness should also have stemmed out from such logic system. This article aims to rearticulate the underlying lucid multi-dimensional logic system, which faded in obscurity only because of time-out loss of the mid-right concept. Retracing this past tacit but important concept could uncover a multi-dimensional system over a point relating to all matters while capturing the central core of the matter. The seemingly unmanageable multidimensional logic was strengthened by verification processes which affirmed its further extensions, and made up the language of the people, the concepts of yin-yang(阴阳), and the development of extensions of Ba Gua(八卦) derivatives, which furthered the interpretation of the space-time properties and Chinese medicine. 展开更多
关键词 multi-dimensional logic system Traditional Chinese medicine YIN-YANG
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Effective stress dissipation by multi-dimensional architecture engineering for ultrafast and ultralong sodium storage
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作者 Man Zhang Jing Zhu +7 位作者 Qianqian Li Fenghua Zheng Sijiang Hu Youguo Huang Hongqiang Wang Xing Ou Qichang Pan Qingyu Li 《Journal of Energy Chemistry》 2025年第2期619-629,I0013,共12页
Stress accumulation is a key factor leading to sodium storage performance deterioration for NiSe_(2)-based anodes.Therefore,inhibiting the concentrated local stress during the sodiataion/desodiation process is crucial... Stress accumulation is a key factor leading to sodium storage performance deterioration for NiSe_(2)-based anodes.Therefore,inhibiting the concentrated local stress during the sodiataion/desodiation process is crucial for acquiring stable NiSe2-based materials for sodium-ion batteries(SIBs),Herein,a stress dissipation strategy driven by architecture engineering is proposed,which can achieve ultrafast and ultralong sodium storage properties.Different from the conventional sphere-like or rod-like architecture,the three-dimensional(3D)flower-like NiSe_(2)@C composite is delicately designed and assembled with onedimensional nanorods and carbon framework.More importantly,the fundamental mechanism of improved structure stability is unveiled by simulations and experimental results simultaneously.It demonstrates that this designed multidimensional flower-like architecture with dispersed nanorods can balance the structural mismatch,avoid concentrated local strain,and relax the internal stress,mainly induced by the unavoidable volume variation during the repeated conversion processes.Moreover,it can provide more Na^(+)-storage sites and multi-directional migration pathways,leading to a fast Na^(+)-migration channel with boosted reaction kinetic.As expected,it delivers superior rate performance(441 mA h g^(-1)at 5.0 A g^(-1))and long cycling stability(563 mA h g^(-1)at 1.0 A g^(-1)over 1000 cycles)for SIBs.This work provides useful insights for designing high-performance conversion-based anode materials for SIBs. 展开更多
关键词 Stress dissipation multi-dimensional architecture Structure engineering Conversion-based anodes Sodium-ion batteries
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Research on Multi-Dimensional Collaborative Strategies in Design Management,Investment Management,and Beyond from the Perspective of Whole-Process Engineering Consulting
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作者 Zexin Chen 《Journal of Architectural Research and Development》 2025年第5期21-28,共8页
This paper explores whole-process engineering consulting,including its application models in public buildings and elderly-friendly projects,such as service integration and whole lifecycle management.It also addresses ... This paper explores whole-process engineering consulting,including its application models in public buildings and elderly-friendly projects,such as service integration and whole lifecycle management.It also addresses the construction of multi-dimensional collaborative theoretical models,public space streamline organization,and other aspects,emphasizing the importance of multi-dimensional collaboration.Additionally,it highlights the role of talent cultivation and digital transformation in enhancing project efficiency. 展开更多
关键词 Whole-process engineering consulting multi-dimensional collaboration Project efficiency
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Practical Application of the Multi-Dimensional Interactive Teaching Model in College English
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作者 Bo Sun 《Journal of Contemporary Educational Research》 2025年第10期106-111,共6页
The multi-dimensional interactive teaching model significantly enhances the effectiveness of college English instruction by emphasizing dynamic engagement between teachers and students,as well as among students themse... The multi-dimensional interactive teaching model significantly enhances the effectiveness of college English instruction by emphasizing dynamic engagement between teachers and students,as well as among students themselves.This paper explores practical strategies for implementing this model,focusing on four key aspects:deepening teachers’understanding of the model through continuous learning,innovating interactive methods such as questioning techniques and practical activities,leveraging modern technology to integrate resources and track learning progress,and establishing a communication platform that centers on student participation.By adopting these approaches,the model fosters a student-centered classroom environment,improves comprehensive English application skills,and optimizes overall teaching quality. 展开更多
关键词 multi-dimensional interactive teaching model Student-centered approach Teacher-student interaction
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Construction of the Practice System of Landscape Architecture Major Based on“Multi-dimensional Integration”
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作者 LI Yinan DING Juan +4 位作者 ZHU Yan WU Jing ZHAO Zhiyan LI Jie XIANG Cheng 《Journal of Landscape Research》 2025年第3期89-92,共4页
During the critical transformation period of landscape architecture major after the adjustment of disciplinary structure and the changes in market demand,private colleges and universities,as important places for culti... During the critical transformation period of landscape architecture major after the adjustment of disciplinary structure and the changes in market demand,private colleges and universities,as important places for cultivating local talents,have pain points such as uneven quality of teachers and students and weak innovation and practice.The practice system with“multi-dimensional Integration”integrates four dimensions:interdisciplinary integration,spatial and temporal intersection,historical inheritance,and behavioral activity,deepens the disciplinary connotation,and integrates the three elements of nature,humanity,and technology,aiming to provide a new path for private colleges and universities to cultivate application-oriented and compound talents with innovative capabilities.In terms of optimizing talent cultivation and adapting to industry changes,this system provides thinking and reference for landscape architecture major,helping the major reshape its core competitiveness and promoting educational innovation and industry development. 展开更多
关键词 Landscape architecture Practice system multi-dimensional integration”model Talent cultivation Teaching reform
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Reliability of multi-dimensional network systems with nodes having stochastic connection ranges
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作者 FU Yuqiang MA Xiaoyang ZHAO Fei 《Journal of Systems Engineering and Electronics》 2025年第4期1017-1023,共7页
This paper proposes a reliability evaluation model for a multi-dimensional network system,which has potential to be applied to the internet of things or other practical networks.A multi-dimensional network system with... This paper proposes a reliability evaluation model for a multi-dimensional network system,which has potential to be applied to the internet of things or other practical networks.A multi-dimensional network system with one source element and multiple sink elements is considered first.Each element can con-nect with other elements within a stochastic connection ranges.The system is regarded as successful as long as the source ele-ment remains connected with all sink elements.An importance measure is proposed to evaluate the performance of non-source elements.Furthermore,to calculate the system reliability and the element importance measure,a multi-valued decision diagram based approach is structured and its complexity is analyzed.Finally,a numerical example about the signal transfer station system is illustrated to analyze the system reliability and the ele-ment importance measure. 展开更多
关键词 multi-dimensional network multi-valued decision diagram stochastic connection range reliability analysis impor-tance measure.
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Multi-dimensional hydrogen bonds regulated emissions of single-molecule system enabling surficial hydrophobicity/hydrophilicity mapping
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作者 Hao Gu Rui Li +6 位作者 Qiuying Li Sheng Lu Yahui Chen Xiaoning Yang Huili Ma Zhijun Xu Xiaoqiang Chen 《Chinese Chemical Letters》 2025年第5期515-520,共6页
Constructing multi-dimensional hydrogen bond(H-bond)regulated single-molecule systems with multiemission remains a challenge.Herein,we report the design of a new excited-state intramolecular proton transfer(ESIPT)feat... Constructing multi-dimensional hydrogen bond(H-bond)regulated single-molecule systems with multiemission remains a challenge.Herein,we report the design of a new excited-state intramolecular proton transfer(ESIPT)featured chromophore(HBT-DPI)that shows flexible emission tunability via the multidimensional regulation of intra-and intermolecular H-bonds.The feature of switchable intramolecular Hbonds is induced via incorporating several hydrogen bond acceptors and donors into one single HBT-DPI molecule,allowing the“turn on/off”of ESIPT process by forming isomers with distinct intramolecular Hbonds configurations.In response to different external H-bonding environments,the obtained four types of crystal/cocrystals vary in the contents of isomers and the molecular packing modes,which are mainly guided by the intermolecular H-bonds,exhibiting non-emissive features or emissions ranging from green to orange.Utilizing the feature of intermolecular H-bond guided molecular packing,we demonstrate the utility of this fluorescent material for visualizing hydrophobic/hydrophilic areas on large-scale heterogeneous surfaces of modified poly(1,1-difluoroethylene)(PVDF)membranes and quantitatively estimating the surface hydrophobicity,providing a new approach for hydrophobicity/hydrophilicity monitoring and measurement.Overall,this study represents a new design strategy for constructing multi-dimensional hydrogen bond regulated ESIPT-based fluorescent materials that enable multiple emissions and unique applications. 展开更多
关键词 multi-dimensional hydrogen bonds Emission regulation Hydrophobicity/hydrophilicity Surficial mapping Excited-state intramolecular proton transfer
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A novel multi-dimensional isolation platform for low-frequency excitations:analysis and experiment
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作者 Lingjun MENG Xiuting SUN Jian XU 《Applied Mathematics and Mechanics(English Edition)》 2025年第12期2241-2264,共24页
To break the limitations of the multi-dimensional(M-D)vibration isolation(VI)platforms with the Stewart-Gough design,such as strongly coupling motions,excessive friction in connections,heavy weight,and limited workspa... To break the limitations of the multi-dimensional(M-D)vibration isolation(VI)platforms with the Stewart-Gough design,such as strongly coupling motions,excessive friction in connections,heavy weight,and limited workspace,this study processes a novel platform integrated by a stiffness-adjustable origami spring sub-structure and a parallel mechanism.The origami-based stiffness-adjustable spring realizes low-frequency VI,and the parallel mechanism symmetry design realizes motions decoupling.In the origami-based sub-leg,the parallel-stack-assembly(PSA)design mechanism with two Miura origami configurations is proposed to generate a symmetrical negative stiffness property.Paired with a linear positive stiffness spring,the origami-based sub-leg has wide-amplitude-high-static-low-dynamic stiffness(WA-HSLDS)characteristics in one direction.Then,with construction of the parallel mechanism connected with origami-based sub-legs,an M-D VI platform is achieved,whose motions in the vertical direction and yaw direction are decoupled with the motions in the other directions.Based on the dynamic model and incremental harmonic balance(IHB)with the arc-length continuation method,appropriate structural parameters in the parallel mechanism part are figured out,and the accurate transmissibility in different directions is defined,which gives the parametric influencing investigations for realization of low-frequency VI performances.Finally,experiments are conducted to validate the accuracy and feasibility of the theoretical methods,and to demonstrate the performance of M-D low-frequency isolation with load-carrying capacity of the proposed VI platform.The integration of the origami into the parallel mechanism results in a compact,efficient,and flexible platform with nonlinear adjustability,offering new possibilities for lightweight M-D VI,and developing the practical applications in high-precision platforms in ocean and aerospace environments. 展开更多
关键词 multi-dimensional(M-D)vibration isolation(VI) wide-amplitude high-static-low-dynamic stiffness(WA-HSLDS) origami-based elastic spring parallel mechanism
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Long-term Cumulative Depressive Symptoms and Incident Cardiovascular Disease in Middle-aged and Older Population:Two Cohort Studies
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作者 Fangfei You Yining Gao +11 位作者 Wenfang Zhong Zhihao Li Jian Gao Dong Shen Xiaomeng Wang Weiqi Song Qi Fu Haoyu Yan Jiahao Xie Huan Chen Hao Yan Chen Mao 《Biomedical and Environmental Sciences》 2026年第1期15-25,共11页
Objective Elevated depressive symptoms are well-documented among geriatric adults with cardiovascular disease(CVD);however,few studies have accounted for long-term cumulative depressive symptom exposure.This study det... Objective Elevated depressive symptoms are well-documented among geriatric adults with cardiovascular disease(CVD);however,few studies have accounted for long-term cumulative depressive symptom exposure.This study determined the relationship between cumulative depressive symptoms and CVD.Methods Individual participant data were obtained from the China Health and Retirement Longitudinal Study(CHARLS)and Health and Retirement Study(HRS).Eligible participants had access to assessment information on depressive symptoms and had no history of CVD at baseline.Long-term cumulative depressive symptoms were estimated by calculating the area under the curve based on the Center for Epidemiological Studies Depression Scale.Results Herein,8,861 participants from CHARLS(mean age:58.58 years;male:48.6%)and 7,284 from HRS(60.94 years;35.0%)were enrolled.The median follow-up period was 5 years for the CHARLS and10 years for the HRS.Compared with the first quartile of cumulative depressive symptoms,the HRs(95%CI)in the fourth quartile were 1.73(1.48,2.02)for predicting CVD(P<0.001),1.83(1.52,2.19)for heart disease(P<0.001),1.53(95%CI:1.17,1.99)for stroke(P=0.002)in CHARLS.For HRS,the HRs(95%CI)were 1.41(95%CI:1.27,1.57;P<0.001),1.42(95%CI:1.26,1.59;P<0.001),and 1.30(95%CI:1.06,1.58;P=0.010)respectively.Strong dose-response relationships were observed,with similar results for the two cohorts.Conclusion Long-term cumulative depressive symptoms were significantly associated with incident CVD in middle-aged and older adults,providing insights into controlling long-term depressive symptoms to improve this cohort's health. 展开更多
关键词 Cumulative depressive symptom CVD COHORT CHARLS HRS
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Mapping the acute trajectory of sport-related concussion outcomes across symptoms,cognition,and blood biomarkers
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作者 SoYoung Ahn Michael Prock +3 位作者 Ji-won Seo Sanghyuk Han David Michael O'Sullivan Wook Song 《Sports Medicine and Health Science》 2026年第2期119-127,共9页
Sport-related concussion(SRC)and its potential neurological sequela represent an emerging global health concern,requiring improved recovery management and strategies for return-to-play(RTP)to enhance brain health in a... Sport-related concussion(SRC)and its potential neurological sequela represent an emerging global health concern,requiring improved recovery management and strategies for return-to-play(RTP)to enhance brain health in athletes.Given the dynamic and multifaceted nature of SRC recovery,the purpose of this review is to synthesize existing literature on post-SRC outcomes in adult athletes,and to outline the temporal trajectories of key recovery indicators(symptoms,cognitive function,blood biomarkers)across distinct recovery phases until resolution.In the acute phase of SRC(first 48 h),symptom scores and brain damage markers peaked immediately,while cognitive impairments and neuroinflammation emerged with a slight delay.Following the initial rise,brain damage marker concentrations rapidly dropped below baseline levels at approximately 48 h following SRC injury.During the early recovery phase,neuroinflammation and most cognitive alterations resolved after 3–5 days,though symptom burden and attention deficits persisted for up to 7 days.Despite prolonged alterations reported in some individuals,recovery markers typically returned to pre-injury levels in the transition phase(≤2 weeks),though mild attention deficits were detected up to 3 weeks,and TNF-α concentrations remained elevated throughout late recovery(>2 weeks).These results reveal distinct temporal discrepancies across recovery markers and emphasize that physiological disturbances can outlast symptom resolution,underscoring the need for both multimodal assessments and appropriately timed evaluations to accurately track recovery progression.Incorporating structured follow-ups at key time points,particularly beyond symptom resolution,may improve RTP decision-making and reduce the risk of premature return and long-term neurological consequences. 展开更多
关键词 Sport-related concussion Recovery Return-to-play symptomS Cognitive function Blood biomarkers Narrative review
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Feasibility of water vapor thermal therapy for treating lower urinary tract symptoms in men with localized prostate cancer on active surveillance:a case series
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作者 Mustufa Babar Farooz Babar +2 位作者 Noah Hawks-Ladds Justin Loloi Michael Ciatto 《The Canadian Journal of Urology》 2026年第1期193-199,共7页
Background:Prostate cancer is a common malignancy,with many men on active surveillance for localized,low-risk disease also experiencing lower urinary tract symptoms(LUTS)from benign prostatic hyperplasia(BPH).Water Va... Background:Prostate cancer is a common malignancy,with many men on active surveillance for localized,low-risk disease also experiencing lower urinary tract symptoms(LUTS)from benign prostatic hyperplasia(BPH).Water Vapor Thermal Therapy(WVTT)is a minimally invasive BPH treatment,but its safety and efficacy in this setting are unclear.Case Description:We report three men with localized PCa on active surveillance who underwent WVTT for LUTS.Conclusions:WVTT appears safe and potentially effective in treating LUTS,especially in those with lower-risk disease and smaller prostate volumes.Further research is needed to confirm safety,efficacy,and optimal patient selection. 展开更多
关键词 lower urinary tract symptoms benign prostatic hyperplasia prostatic neoplasms active surveillance case report
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Brain insulin resistance and neuropsychiatric symptoms in Alzheimer's disease:A role for dopamine signaling
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作者 Anastasia Kontogianni Hongbin Yang Wenqiang Chen 《Neural Regeneration Research》 2026年第5期1995-1996,共2页
Type 2 diabetes mellitus has central complications:Diabetes,a metabolic disorder primarily characterized by hyperglycemia due to insufficient insulin secretion,or impaired insulin signaling,has significant central com... Type 2 diabetes mellitus has central complications:Diabetes,a metabolic disorder primarily characterized by hyperglycemia due to insufficient insulin secretion,or impaired insulin signaling,has significant central complications.Type 2 diabetes mellitus(T2DM),the most prevalent type of diabetes,affects more than 38 million individuals in the United States(approximately 1 in 10)and is defined by chronic hyperglycemia and insulin resistance,which refers to a reduced cellular response to insulin. 展开更多
关键词 reduced cellular response insulin dopamine signaling insulin resistancewhich metabolic disorder type diabetes mellitus brain insulin resistance Alzheimers disease neuropsychiatric symptoms
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Neuropsychiatric symptoms and apolipoprotein E genotypes in neurocognitive disorders
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作者 Madia Lozupone Ivana Leccisotti +9 位作者 Anita Mollica Giuseppe Berardino Maria Claudia Moretti Mario Altamura Antonello Bellomo Antonio Daniele Vittorio Dibello Vincenzo Solfrizzi Emanuela Resta Francesco Panza 《Neural Regeneration Research》 2026年第4期1528-1541,共14页
Complex genetic relationships between neurodegenerative disorders and neuropsychiatric symptoms have been shown, suggesting shared pathogenic mechanisms and emphasizing the potential for developing common therapeutic ... Complex genetic relationships between neurodegenerative disorders and neuropsychiatric symptoms have been shown, suggesting shared pathogenic mechanisms and emphasizing the potential for developing common therapeutic targets. Apolipoprotein E(APOE) genotypes and their corresponding protein(Apo E) isoforms may influence the biophysical properties of the cell membrane lipid bilayer. However, the role of APOE in central nervous system pathophysiology extended beyond its lipid transport function. In the present review article, we analyzed the links existing between APOE genotypes and the neurobiology of neuropsychiatric symptoms in neurodegenerative and vascular diseases. APOE genotypes(APOE ε2, APOE ε3, and APOE ε4) were implicated in common mechanisms underlying a wide spectrum of neurodegenerative diseases, including sporadic Alzheimer's disease, synucleinopathies such as Parkinson's disease and Lewy body disease, stroke, and traumatic brain injury. These shared pathways often involved neuroinflammation, abnormal protein accumulation, or responses to acute detrimental events. Across these conditions, APOE variants are believed to contribute to the modulation of inflammatory responses, the regulation of amyloid and tau pathology, as well as the clearance of proteins such as α-synuclein. The bidirectional interactions among Apo E, amyloid and mitochondrial metabolism, immunomodulatory effects, neuronal repair, and remodeling underscored the complexity of Apo E's role in neuropsychiatric symptoms associated with these conditions since from early phases of cognitive impairment such as mild cognitive impairment and mild behavioral impairment. Besides Apo E-specific isoforms' link to increased neuropsychiatric symptoms in Alzheimer's disease(depression, psychosis, aberrant motor behaviors, and anxiety, not apathy), the APOE ε4 genotype was also considered a significant genetic risk factor for Lewy body disease and its worse cognitive outcomes. Conversely, the APOE ε2 variant has been observed not to exert a protective effect equally in all neurodegenerative diseases. Specifically, in Lewy body disease, this variant may delay disease onset, paralleling its protective role in Alzheimer's disease, although its role in frontotemporal dementia is uncertain. The APOE ε4 genotype has been associated with adverse cognitive outcomes across other various neurodegenerative conditions. In Parkinson's disease, the APOE ε4 allele significantly impacted cognitive performance, increasing the risk of developing dementia, even in cases of pure synucleinopathies with minimal co-pathology from Alzheimer's disease. Similarly, in traumatic brain injury, recovery rates varied, with APOE ε4 carriers demonstrating a greater risk of poor long-term cognitive outcomes and elevated levels of neuropsychiatric symptoms. Furthermore, APOE ε4 influenced the age of onset and severity of stroke, as well as the likelihood of developing stroke-associated dementia, potentially due to its role in compromising endothelial integrity and promoting blood–brain barrier dysfunction. 展开更多
关键词 Alzheimer's disease ApoE isoforms apolipoprotein E gene DEPRESSION Lewy body disease mild cognitive impairment NEUROINFLAMMATION neuropsychiatric symptoms Parkinson's disease stroke traumatic brain injury
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The Study on College English Writing Based on Multi-dimensional Feed-back Mode
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作者 骆敏 徐敏娜 《海外英语》 2020年第12期273-274,共2页
The study constructed a multi-dimensional feedback mode integrating teacher feedback, peer feedback and network feedback, and applied it in the teaching of College English Writing. After 16 weeks of teaching, the stud... The study constructed a multi-dimensional feedback mode integrating teacher feedback, peer feedback and network feedback, and applied it in the teaching of College English Writing. After 16 weeks of teaching, the students in the multi-dimen-sional feedback class had significantly better overall writing scores than those in the teacher-feedback class. In terms of individual scores, multi-dimensional feedback played a better role in improving vocabulary and grammar than the class using teacher feed-back. However, there were no significant differences in the responses of writing tasks, coherence and cohesion. The study showed that most students were satisfied with the mode, believing that it was helpful to relieve writing anxiety, stimulate writing interest and improve their writing level. 展开更多
关键词 College English Writing multi-dimensional feedback MODE
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Structural Engineering of Hierarchical Aerogels Comprised of Multi-dimensional Gradient Carbon Nanoarchitectures for Highly Efficient Microwave Absorption 被引量:19
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作者 Yongpeng Zhao Xueqing Zuo +11 位作者 Yuan Guo Hui Huang Hao Zhang Ting Wang Ningxuan Wen Huan Chen Tianze Cong Javid Muhammad Xuan Yang Xinnan Wang Zeng Fan Lujun Pan 《Nano-Micro Letters》 SCIE EI CAS CSCD 2021年第9期344-363,共20页
Recently,multilevel structural carbon aerogels are deemed as attractive candidates for microwave absorbing materials.Nevertheless,excessive stack and agglomeration for low-dimension carbon nanomaterials inducing imped... Recently,multilevel structural carbon aerogels are deemed as attractive candidates for microwave absorbing materials.Nevertheless,excessive stack and agglomeration for low-dimension carbon nanomaterials inducing impedance mismatch are significant challenges.Herein,the delicate“3D helix-2D sheet-1D fiber-0D dot”hierarchical aerogels have been successfully synthesized,for the first time,by sequential processes of hydrothermal self-assembly and in-situ chemical vapor deposition method.Particularly,the graphene sheets are uniformly intercalated by 3D helical carbon nanocoils,which give a feasible solution to the mentioned problem and endows the as-obtained aerogel with abundant porous structures and better dielectric properties.Moreover,by adjusting the content of 0D core-shell structured particles and the parameters for growth of the 1D carbon nanofibers,tunable electromagnetic properties and excellent impedance matching are achieved,which plays a vital role in the microwave absorption performance.As expected,the optimized aerogels harvest excellent performance,including broad effective bandwidth and strong reflection loss at low filling ratio and thin thickness.This work gives valuable guidance and inspiration for the design of hierarchical materials comprised of dimensional gradient structures,which holds great application potential for electromagnetic wave attenuation. 展开更多
关键词 Hierarchical aerogels multi-dimensional gradient Carbon nanocoils Microwave absorption
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Seismic fragility analysis of highway bridges considering multi-dimensional performance limit state 被引量:17
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作者 Wang, Qi'ang Wu, Ziyan Liu, Shukui 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2012年第2期185-193,共9页
Fragility analysis for highway bridges has become increasingly important in the risk assessment of highway transportation networks exposed to seismic hazards. This study introduces a methodology to calculate fragility... Fragility analysis for highway bridges has become increasingly important in the risk assessment of highway transportation networks exposed to seismic hazards. This study introduces a methodology to calculate fragility that considers multi-dimensional performance limit state parameters and makes a first attempt to develop fragility curves for a multi-span continuous (MSC) concrete girder bridge considering two performance limit state parameters: column ductility and transverse deformation in the abutments. The main purpose of this paper is to show that the performance limit states, which are compared with the seismic response parameters in the calculation of fragility, should be properly modeled as randomly interdependent variables instead of deterministic quantities. The sensitivity of fragility curves is also investigated when the dependency between the limit states is different. The results indicate that the proposed method can be used to describe the vulnerable behavior of bridges which are sensitive to multiple response parameters and that the fragility information generated by this method will be more reliable and likely to be implemented into transportation network loss estimation. 展开更多
关键词 highway bridge seismic hazard multi-dimensional performance limit state fragility curves sensitivity
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Hydraulic directional valve fault diagnosis using a weighted adaptive fusion of multi-dimensional features of a multi-sensor 被引量:13
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作者 Jin-chuan SHI Yan REN +1 位作者 He-sheng TANG Jia-wei XIANG 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2022年第4期257-271,共15页
Because the hydraulic directional valve usually works in a bad working environment and is disturbed by multi-factor noise,the traditional single sensor monitoring technology is difficult to use for an accurate diagnos... Because the hydraulic directional valve usually works in a bad working environment and is disturbed by multi-factor noise,the traditional single sensor monitoring technology is difficult to use for an accurate diagnosis of it.Therefore,a fault diagnosis method based on multi-sensor information fusion is proposed in this paper to reduce the inaccuracy and uncertainty of traditional single sensor information diagnosis technology and to realize accurate monitoring for the location or diagnosis of early faults in such valves in noisy environments.Firstly,the statistical features of signals collected by the multi-sensor are extracted and the depth features are obtained by a convolutional neural network(CNN)to form a complete and stable multi-dimensional feature set.Secondly,to obtain a weighted multi-dimensional feature set,the multi-dimensional feature sets of similar sensors are combined,and the entropy weight method is used to weight these features to reduce the interference of insensitive features.Finally,the attention mechanism is introduced to improve the dual-channel CNN,which is used to adaptively fuse the weighted multi-dimensional feature sets of heterogeneous sensors,to flexibly select heterogeneous sensor information so as to achieve an accurate diagnosis.Experimental results show that the weighted multi-dimensional feature set obtained by the proposed method has a high fault-representation ability and low information redundancy.It can diagnose simultaneously internal wear faults of the hydraulic directional valve and electromagnetic faults of actuators that are difficult to diagnose by traditional methods.This proposed method can achieve high fault-diagnosis accuracy under severe working conditions. 展开更多
关键词 Hydraulic directional valve Internal fault diagnosis Weighted multi-dimensional features Multi-sensor information fusion
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Applications of multi-dimensional schemes on unstructured grids for high-accuracy heat flux prediction 被引量:2
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作者 Yunbo Wan Nianhua Wang +1 位作者 Laiping Zhang Yewei Gui 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2020年第1期57-71,共15页
The simulation of hypersonic flows with fully unstructured(tetrahedral)grids has severe problems with respect to the prediction of stagnation region heating,due to the random face orientation without alignment to the ... The simulation of hypersonic flows with fully unstructured(tetrahedral)grids has severe problems with respect to the prediction of stagnation region heating,due to the random face orientation without alignment to the bow shock.To improve the accuracy of aero-heating predictions,three multi-dimensional approaches on unstructured grids are coupled in our Reynolds-averaged Navier-Stokes(RANS)solver,including multi-dimensional upwind flux reconstruction(MUP),multi-dimensional limiter(MLP-u2)and multi-dimensional gradient reconstruction(MLR).The coupled multi-dimensional RANS solver is validated by several typical verification and validation(V&V)cases,including hypersonic flows over a cylinder,a blunt biconic,and a double-ellipsoid,with commonly used prism/tetrahedral hybrid grids.Finally,the coupled multi-dimensional solver is applied to simulating the heat flux distribution over a 3D engineering configuration,i.e.a Hermes-like space shuttle model.The obtained numerical results are compared with experimental data.The predicted results demonstrate that the coupled multi-dimensional approach has a good prediction capability on aerodynamic heating over a wide range of complex engineering configurations. 展开更多
关键词 Heat-flux prediction Unstructured grid multi-dimensional gradient reconstruction multi-dimensional limiter multi-dimensional upwind scheme
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