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Multi-dimensional expansion of urban space through the lens of land use:The case study of Nanjing City, China 被引量:1
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作者 乔伟峰 高军波 +3 位作者 郭远智 冀青青 吴菊 曹敏 《Journal of Geographical Sciences》 SCIE CSCD 2019年第5期749-761,共13页
The study of multi-dimensional expansion of urban space(MEUS) addresses the laws of urban spatial expansion from all directions and angles. Using Nanjing as an example,this paper constructs multi-temporal, urban three... The study of multi-dimensional expansion of urban space(MEUS) addresses the laws of urban spatial expansion from all directions and angles. Using Nanjing as an example,this paper constructs multi-temporal, urban three-dimensional models based on RS and GIS technology and then conducts qualitative and quantitative analysis of MEUS using plot ratio change maps and MEUS quantitative index for built-up areas. Based especially on the concept of volume growth contribution rate, this paper analyzes the characteristics of MEUS in different stages. The results show that in 2000–2004, planar expansion played the main role,the internal potential development(IPD) intensity of the urban built-up areas was relatively large, and the volume growth contribution rate was low; in 2004–2008, planar expansion accelerated, and IPD slowed down; in 2008–2012, planar expansion slowed while IPD intensity increased; the contribution rates of volume growth of urban IPD for the three periods were 22.21%, 24.51% and 73.38%, respectively. This study expands the research perspective of urban spatial expansion, and the adopted methods are instructive and meaningful for MEUS research. In addition, the results of this study will deepen the understanding of MEUS laws and help improve scientific decision-making for urban planning and urban land use management. 展开更多
关键词 urban land use PLOT ratio change map multi-dimensional expansion volume growth CONTRIBUTION rate NANJING
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Composite anti-disturbance predictive control of unmanned systems with time-delay using multi-dimensional Taylor network 被引量:1
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作者 Chenlong LI Wenshuo LI Zejun ZHANG 《Chinese Journal of Aeronautics》 2025年第7期589-600,共12页
A composite anti-disturbance predictive control strategy employing a Multi-dimensional Taylor Network(MTN)is presented for unmanned systems subject to time-delay and multi-source disturbances.First,the multi-source di... A composite anti-disturbance predictive control strategy employing a Multi-dimensional Taylor Network(MTN)is presented for unmanned systems subject to time-delay and multi-source disturbances.First,the multi-source disturbances are addressed according to their specific characteristics as follows:(A)an MTN data-driven model,which is used for uncertainty description,is designed accompanied with the mechanism model to represent the unmanned systems;(B)an adaptive MTN filter is used to remove the influence of the internal disturbance;(C)an MTN disturbance observer is constructed to estimate and compensate for the influence of the external disturbance;(D)the Extended Kalman Filter(EKF)algorithm is utilized as the learning mechanism for MTNs.Second,to address the time-delay effect,a recursiveτstep-ahead MTN predictive model is designed utilizing recursive technology,aiming to mitigate the impact of time-delay,and the EKF algorithm is employed as its learning mechanism.Then,the MTN predictive control law is designed based on the quadratic performance index.By implementing the proposed composite controller to unmanned systems,simultaneous feedforward compensation and feedback suppression to the multi-source disturbances are conducted.Finally,the convergence of the MTN and the stability of the closed-loop system are established utilizing the Lyapunov theorem.Two exemplary applications of unmanned systems involving unmanned vehicle and rigid spacecraft are presented to validate the effectiveness of the proposed approach. 展开更多
关键词 multi-dimensional Taylor network Composite anti-disturbance Predictive control Unmanned systems Multi-source disturbances TIME-DELAY
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Research on expansion joint for high-speed railway long-span bridges in China 被引量:1
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作者 Hui Guo Jinzhou Jiang +8 位作者 Suoting Hu Chun Yang Qiqi Xiang Kou Luo Xinxin Zhao Bing Li Ziquan Yan Liubin Niu Jianye Zhao 《Railway Sciences》 2025年第1期52-81,共30页
Purpose–The bridge expansion joint(BEJ)is a key device for accommodating spatial displacement at the beam end,and for providing vertical support for running trains passing over the gap between the main bridge and the... Purpose–The bridge expansion joint(BEJ)is a key device for accommodating spatial displacement at the beam end,and for providing vertical support for running trains passing over the gap between the main bridge and the approach bridge.For long-span railway bridges,it must also be coordinated with rail expansion joint(REJ),which is necessary to accommodate the expansion and contraction of,and reducing longitudinal stress in,the rails.The main aim of this study is to present analysis of recent developments in the research and application of BEJs in high-speed railway(HSR)long-span bridges in China,and to propose a performance-based integral design method for BEJs used with REJs,from both theoretical and engineering perspectives.Design/methodology/approach–The study first presents a summary on the application and maintenance of BEJs in HSR long-span bridges in China representing an overview of their state of development.Results of a survey of typical BEJ faults were analyzed,and field testing was conducted on a railway cable-stayed bridge in order to obtain information on the major mechanical characteristics of its BEJ under train load.Based on the above,a performance-based integral design method for BEJs with maximum expansion range 1600 mm(±800 mm),was proposed,covering all stages from overall conceptual design to consideration of detailed structural design issues.The performance of the novel BEJ design thus derived was then verified via theoretical analysis under different scenarios,full-scale model testing,and field testing and commissioning.Findings–Two major types of BEJs,deck-type and through-type,are used in HSR long-span bridges in China.Typical BEJ faults were found to mainly include skewness of steel sleepers at the bridge gap,abnormally large longitudinal frictional resistance,and flexural deformation of the scissor mechanisms.These faults influence BEJ functioning,and thus adversely affect track quality and train running performance at the beam end.Due to their simple and integral structure,deck-type BEJs with expansion range 1200 mm(±600 mm)or less have been favored as a solution offering improved operational conditions,and have emerged as a standard design.However,when the expansion range exceeds the above-mentioned value,special design work becomes necessary.Therefore,based on engineering practice,a performance-based integral design method for BEJs used with REJs was proposed,taking into account four major categories of performance requirements,i.e.,mechanical characteristics,train running quality,durability and insulation performance.Overall BEJ design must mainly consider component strength and the overall stiffness of BEJ;the latter factor in particular has a decisive influence on train running performance at the beam end.Detailed BEJ structural design must stress minimization of the frictional resistance of its sliding surface.The static and dynamic performance of the newlydesigned BEJ with expansion range 1600 mm have been confirmed to be satisfactory,via numerical simulation,full-scale model testing,and field testing and commissioning.Originality/value–This research provides a broad overview of the status of BEJs with large expansion range in HSR long-span bridges in China,along with novel insights into their design. 展开更多
关键词 High-speed railway(HSR) Long-span bridge Bridge expansion joint(BEJ) Integral design Rail expansion joint(REJ) Overall stiffness Longitudinal frictional resistance
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Safety assessment of overcharged batteries and a novel passive warning method based on relaxation expansion force 被引量:1
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作者 Long Chen Shaohong Zeng +4 位作者 Jiahua Li Kuijie Li Ruixin Ma Jizhen Liu Weixiong Wu 《Journal of Energy Chemistry》 2025年第6期595-607,I0013,共14页
Due to batteries inconsistencies and potential faults in battery management systems,slight overcharging remains a common yet insufficiently understood safety risk,lacking effective warning methods.To illuminate the de... Due to batteries inconsistencies and potential faults in battery management systems,slight overcharging remains a common yet insufficiently understood safety risk,lacking effective warning methods.To illuminate the degradation behavior and failure mechanism of various overcharged states(100%SOC,105%SOC,110%SOC,and 115%SOC),multiple advanced in-situ characterization techniques(accelerating rate calorimeter,electrochemical impedance spectroscopy,ultrasonic scanning,and expansion instrument)were utilized.Additionally,re-overcharge-induced thermal runaway(TR)tests were conducted,with a specific emphasis on the evolution of the expansion force signal.Results indicated significant degradation at 110%SOC including conductivity loss,loss of lithium inventory,and loss of active material accompanied by internal gas generation.These failure behaviors slow down the expansion force rate during reovercharging,reducing the efficacy of active warnings that depend on rate thresholds of expansion force.Specifically,the warning time for 115%SOC battery is only 144 s,which is 740 s shorter than that for fresh battery,and the time to TR is advanced by 9 min.Moreover,the initial self-heating temperature(T1)is reduced by 62.4℃compared to that of fresh battery,reaching only 70.8℃.To address the low safety of overcharged batteries,a passive overcharge warning method utilizing relaxation expansion force was proposed,based on the continued gas generation after stopping charging,leading to a sustained increase in force.Compared to active methods that rely on thresholds of expansion force rate,the passive method can issue warnings 115 s earlier.By combining the passive and active warning methods,guaranteed effective overcharge warning can be issued 863-884 s before TR.This study introduces a novel perspective for enhancing the safety of batteries. 展开更多
关键词 Lithium-ion battery Slight overcharging Thermal runaway Overcharging warning Safety assessment Relaxation expansion force
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Tuning negative thermal expansion in Sm_(0.85)Zn_(0.15)MnO_(3−δ)via synthesis optimization for enhancing the stability of heterostructured solid oxide fuel cell cathodes 被引量:1
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作者 Jakub Fudalewski Piotr Winiarz Kun Zheng 《International Journal of Minerals,Metallurgy and Materials》 2025年第11期2689-2698,共10页
Minimizing the thermal expansion coefficient(TEC)mismatch between the cathode and electrolyte in solid oxide fuel cells is crucial for achieving stable,durable operation and high performance.Recently,materials with ne... Minimizing the thermal expansion coefficient(TEC)mismatch between the cathode and electrolyte in solid oxide fuel cells is crucial for achieving stable,durable operation and high performance.Recently,materials with negative thermal expansion(NTE)have at-tracted significant attention as effective additives for tailoring the thermomechanical properties of electrodes and enhancing cell durability.In this work,for the first time,single-phase NTE perovskite Sm_(0.85)Zn_(0.15)MnO_(3−δ)(SZM15)was successfully synthesized via the sol-gel method,eliminating the unwanted ZnO phase typically observed in materials obtained through the conventional solid-state reaction route.The sol-gel approach proved highly advantageous,offering low cost,robustness,excellent chemical homogeneity,precise compositional control,and high phase purity.After optimization of synthesis parameters,a negative TEC of approximately−6.5×10^(−6)K^(−1)was achieved in the 400-850℃range.SZM15 was then incorporated as an additive(10wt%-50wt%)into a SmBa0.5Sr0.5CoCuO_(5+δ)(SBSCCO)cathode to tune the thermomechanical properties with a La_(0.8)Sr_(0.2)Ga_(0.8)Mg_(0.2)O_(3−δ)(LSGM)electrolyte,achieving a minimal TEC mismatch of only 1%.Notably,the SBSCCO+10wt%SZM15 composite cathode exhibited the lowest polarization resistance of 0.019Ω·cm^(2)at 900℃,showing approximately 70%lower than that of the pristine cathode.Excellent long-term stability after 100 h of operation was achieved.In addition,a high peak power density of 680 mW·cm^(−2)was achieved in a Ni-YSZ(yttria-stabilized zirconia)|YSZ|Ce_(0.9)Gd_(0.1)O_(2−δ)(GDC10)|SBSCCO+10wt%SZM15 anode-supported fuel cell at 850℃,highlighting the effectiveness of incorporating NTE materials as a promising strategy for regulating the thermomechanical properties and improving the long-term stability of intermediate temperature solid oxide fuel cells(IT-SOFCs). 展开更多
关键词 negative thermal expansion solid oxide fuel cell cathodes for solid oxide fuel cells sol-gel synthesis method
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On the Relative Growth Rate of the Digits in Sylvester Continued Fraction Expansions
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作者 LV Meiying RAO Guilin 《应用数学》 北大核心 2025年第2期468-476,共9页
For the Sylvester continued fraction expansions of real numbers,FAN et al.(2007)proved that,for almost all real numbers,the nth partial quotient grows exponentially with respect to the product of the first n-1 partial... For the Sylvester continued fraction expansions of real numbers,FAN et al.(2007)proved that,for almost all real numbers,the nth partial quotient grows exponentially with respect to the product of the first n-1 partial quotients.In this paper,we establish the Hausdorff dimension of the exceptional set where the growth rate is a general function. 展开更多
关键词 Sylvester continued fraction expansions Growth rate Hausdorff dimension
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Evolution of the volume expansion of SiO/C composite electrodes in lithium-ion batteries during aging cycles
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作者 Haosong Yang Kai Sun +2 位作者 Xueyan Li Peng Tan Lili Gong 《中国科学技术大学学报》 北大核心 2025年第2期27-33,26,I0001,共9页
As a negative electrode material for lithium-ion batteries,silicon monoxide(SiO)suffers from dramatic volume changes during cycling,causing excessive stress within the electrode and resulting in electrode deformation ... As a negative electrode material for lithium-ion batteries,silicon monoxide(SiO)suffers from dramatic volume changes during cycling,causing excessive stress within the electrode and resulting in electrode deformation and fragmentation.This ultimately leads to a decrease in cell capacity.The trends of volume expansion and capacity change of the SiO/graphite(SiO/C)composite electrode during cycling were investigated via in situ expansion monitoring.First,a series of expansion test schemes were designed,and the linear relationship between negative electrode expansion and cell capacity degradation was quantitatively analyzed.Then,the effects of different initial pressures on the long-term cycling performance of the cell were evaluated.Finally,the mechanism of their effects was analyzed by scanning electron microscope.The results show that after 50 cycles,the cell capacity decreases from 2.556 mAh to 1.689 mAh,with a capacity retention ratio(CRR)of only 66.08%.A linear relationship between the capacity retention ratio and thickness expansion was found.Electrochemical measurements and scanning electron microscope images demonstrate that intense stress inhibits the lithiation of the negative electrode and that the electrode is more susceptible to irreversible damage during cycling.Overall,these results reveal the relationship between the cycling performance of SiO and the internal pressure of the electrode from a macroscopic point of view,which provides some reference for the application of SiO/C composite electrodes in lithium-ion batteries. 展开更多
关键词 lithium-ion batteries in situ expansion measurement initial stress cycle life SiO/C composite electrode
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Impact of urban construction land gradient expansion on land subsidence in mountainous cities
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作者 JIAO Weijie ZHOU Liang +3 位作者 WANG Shaohua GAO Hong HUANG Chunlin YUAN Heli 《Journal of Mountain Science》 2025年第7期2586-2604,共19页
The expansion of construction land on slopes in mountainous cities like Lanzhou has addressed the shortage of flat land but compromised slope stability,leading to uneven land subsidence and risks to infrastructure.Thi... The expansion of construction land on slopes in mountainous cities like Lanzhou has addressed the shortage of flat land but compromised slope stability,leading to uneven land subsidence and risks to infrastructure.This study assessed the land subsidence before and after urban expansion in five areas of Lanzhou by using slope spectrum construction method and gradient expansion intensity measurement that integrated with SBAS-InSAR technology.The results show that construction land on slopes over 20°increased significantly,accounting for 16%of new construction land.The average slope spectrum index was 4.02,with the upper slope limit rising by 8.2°.The land subsidence rate threshold increased by 10 mm/a,and the proportion of pixels experiencing subsidence greater than 5 mm/year rose from 3.63%to 5.24%.Increased construction intensity on slopes caused higher and faster subsidence,which diminished with greater distance from the expansion areas.Areas with slopes between 10°and 25°saw the greatest acceleration in subsidence.Geological composition,building density,groundwater exploitation,and cut-and-fill thickness collectively influence land subsidence rates.This study provides a scientific basis for mitigating geological disaster risks and promoting safe urban development in mountainous cities. 展开更多
关键词 Gradient expansion Land subsidence SBAS-InSAR Land creation Urban expansion
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Retraced Multi-dimensional Chinese Logic System behind Chinese Medicine
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作者 Edwin C.L.Yu 《Chinese Medicine and Culture》 2025年第1期1-12,共12页
The ancient tacit knowledge behind the logic system permeated the culture and promoted numerous impactful inventions throughout the history. Traditional Chinese medicine with its effectiveness should also have stemmed... The ancient tacit knowledge behind the logic system permeated the culture and promoted numerous impactful inventions throughout the history. Traditional Chinese medicine with its effectiveness should also have stemmed out from such logic system. This article aims to rearticulate the underlying lucid multi-dimensional logic system, which faded in obscurity only because of time-out loss of the mid-right concept. Retracing this past tacit but important concept could uncover a multi-dimensional system over a point relating to all matters while capturing the central core of the matter. The seemingly unmanageable multidimensional logic was strengthened by verification processes which affirmed its further extensions, and made up the language of the people, the concepts of yin-yang(阴阳), and the development of extensions of Ba Gua(八卦) derivatives, which furthered the interpretation of the space-time properties and Chinese medicine. 展开更多
关键词 multi-dimensional logic system Traditional Chinese medicine YIN-YANG
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Effective stress dissipation by multi-dimensional architecture engineering for ultrafast and ultralong sodium storage
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作者 Man Zhang Jing Zhu +7 位作者 Qianqian Li Fenghua Zheng Sijiang Hu Youguo Huang Hongqiang Wang Xing Ou Qichang Pan Qingyu Li 《Journal of Energy Chemistry》 2025年第2期619-629,I0013,共12页
Stress accumulation is a key factor leading to sodium storage performance deterioration for NiSe_(2)-based anodes.Therefore,inhibiting the concentrated local stress during the sodiataion/desodiation process is crucial... Stress accumulation is a key factor leading to sodium storage performance deterioration for NiSe_(2)-based anodes.Therefore,inhibiting the concentrated local stress during the sodiataion/desodiation process is crucial for acquiring stable NiSe2-based materials for sodium-ion batteries(SIBs),Herein,a stress dissipation strategy driven by architecture engineering is proposed,which can achieve ultrafast and ultralong sodium storage properties.Different from the conventional sphere-like or rod-like architecture,the three-dimensional(3D)flower-like NiSe_(2)@C composite is delicately designed and assembled with onedimensional nanorods and carbon framework.More importantly,the fundamental mechanism of improved structure stability is unveiled by simulations and experimental results simultaneously.It demonstrates that this designed multidimensional flower-like architecture with dispersed nanorods can balance the structural mismatch,avoid concentrated local strain,and relax the internal stress,mainly induced by the unavoidable volume variation during the repeated conversion processes.Moreover,it can provide more Na^(+)-storage sites and multi-directional migration pathways,leading to a fast Na^(+)-migration channel with boosted reaction kinetic.As expected,it delivers superior rate performance(441 mA h g^(-1)at 5.0 A g^(-1))and long cycling stability(563 mA h g^(-1)at 1.0 A g^(-1)over 1000 cycles)for SIBs.This work provides useful insights for designing high-performance conversion-based anode materials for SIBs. 展开更多
关键词 Stress dissipation multi-dimensional architecture Structure engineering Conversion-based anodes Sodium-ion batteries
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Construction of Integrated Education Model in Rural Communities:Research on Resource Aggregation and Multi-dimensional Linkage Path
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作者 Xianfei Ke 《New Horizon of Education》 2025年第1期48-61,共14页
This study focuses on the main problems encountered by rural community education and explores the main problems in key aspects such as resource integration and allocation,multi-party collaboration and sustainable deve... This study focuses on the main problems encountered by rural community education and explores the main problems in key aspects such as resource integration and allocation,multi-party collaboration and sustainable development through empirical analysis according to the theoretical framework of integrated education.The study finds that from the three dimensions of integration subject,integrated curriculum and integration mode,an integrated education system should be created on the basis of community,the social support system should be improved,the implementation of the rural revitalization strategy should be promoted,and the goal of talent training should be realized. 展开更多
关键词 Rural Community Education Integrated Education Resource Aggregation multi-dimensional Linkage
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Research on Multi-Dimensional Collaborative Strategies in Design Management,Investment Management,and Beyond from the Perspective of Whole-Process Engineering Consulting
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作者 Zexin Chen 《Journal of Architectural Research and Development》 2025年第5期21-28,共8页
This paper explores whole-process engineering consulting,including its application models in public buildings and elderly-friendly projects,such as service integration and whole lifecycle management.It also addresses ... This paper explores whole-process engineering consulting,including its application models in public buildings and elderly-friendly projects,such as service integration and whole lifecycle management.It also addresses the construction of multi-dimensional collaborative theoretical models,public space streamline organization,and other aspects,emphasizing the importance of multi-dimensional collaboration.Additionally,it highlights the role of talent cultivation and digital transformation in enhancing project efficiency. 展开更多
关键词 Whole-process engineering consulting multi-dimensional collaboration Project efficiency
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Practical Application of the Multi-Dimensional Interactive Teaching Model in College English
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作者 Bo Sun 《Journal of Contemporary Educational Research》 2025年第10期106-111,共6页
The multi-dimensional interactive teaching model significantly enhances the effectiveness of college English instruction by emphasizing dynamic engagement between teachers and students,as well as among students themse... The multi-dimensional interactive teaching model significantly enhances the effectiveness of college English instruction by emphasizing dynamic engagement between teachers and students,as well as among students themselves.This paper explores practical strategies for implementing this model,focusing on four key aspects:deepening teachers’understanding of the model through continuous learning,innovating interactive methods such as questioning techniques and practical activities,leveraging modern technology to integrate resources and track learning progress,and establishing a communication platform that centers on student participation.By adopting these approaches,the model fosters a student-centered classroom environment,improves comprehensive English application skills,and optimizes overall teaching quality. 展开更多
关键词 multi-dimensional interactive teaching model Student-centered approach Teacher-student interaction
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Construction of the Practice System of Landscape Architecture Major Based on“Multi-dimensional Integration”
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作者 LI Yinan DING Juan +4 位作者 ZHU Yan WU Jing ZHAO Zhiyan LI Jie XIANG Cheng 《Journal of Landscape Research》 2025年第3期89-92,共4页
During the critical transformation period of landscape architecture major after the adjustment of disciplinary structure and the changes in market demand,private colleges and universities,as important places for culti... During the critical transformation period of landscape architecture major after the adjustment of disciplinary structure and the changes in market demand,private colleges and universities,as important places for cultivating local talents,have pain points such as uneven quality of teachers and students and weak innovation and practice.The practice system with“multi-dimensional Integration”integrates four dimensions:interdisciplinary integration,spatial and temporal intersection,historical inheritance,and behavioral activity,deepens the disciplinary connotation,and integrates the three elements of nature,humanity,and technology,aiming to provide a new path for private colleges and universities to cultivate application-oriented and compound talents with innovative capabilities.In terms of optimizing talent cultivation and adapting to industry changes,this system provides thinking and reference for landscape architecture major,helping the major reshape its core competitiveness and promoting educational innovation and industry development. 展开更多
关键词 Landscape architecture Practice system multi-dimensional integration”model Talent cultivation Teaching reform
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Reliability of multi-dimensional network systems with nodes having stochastic connection ranges
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作者 FU Yuqiang MA Xiaoyang ZHAO Fei 《Journal of Systems Engineering and Electronics》 2025年第4期1017-1023,共7页
This paper proposes a reliability evaluation model for a multi-dimensional network system,which has potential to be applied to the internet of things or other practical networks.A multi-dimensional network system with... This paper proposes a reliability evaluation model for a multi-dimensional network system,which has potential to be applied to the internet of things or other practical networks.A multi-dimensional network system with one source element and multiple sink elements is considered first.Each element can con-nect with other elements within a stochastic connection ranges.The system is regarded as successful as long as the source ele-ment remains connected with all sink elements.An importance measure is proposed to evaluate the performance of non-source elements.Furthermore,to calculate the system reliability and the element importance measure,a multi-valued decision diagram based approach is structured and its complexity is analyzed.Finally,a numerical example about the signal transfer station system is illustrated to analyze the system reliability and the ele-ment importance measure. 展开更多
关键词 multi-dimensional network multi-valued decision diagram stochastic connection range reliability analysis impor-tance measure.
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Expansion strategies for Vδ2 γδT cells in cancer immunotherapy: Activation, cytokines, and culture conditions
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作者 Natalia Lehman Michal Zarobkiewicz 《World Journal of Clinical Oncology》 2025年第10期186-197,共12页
TheγδT cells are an emerging class of immune effectors with potent antitumor activity,bridging innate and adaptive immunity.Their unique ability to recognise stress-induced ligands independently of major histocompat... TheγδT cells are an emerging class of immune effectors with potent antitumor activity,bridging innate and adaptive immunity.Their unique ability to recognise stress-induced ligands independently of major histocompatibility complex restriction makes them attractive candidates for cancer immunotherapy.However,the clinical application ofγδT cells requires efficient in vitro expansion strategies to generate large numbers of functional cells.This mini-review explores the latest advancements inγδT cell expansion protocols,focusing on key activation stimuli,cytokine support,and culture conditions that optimise proliferation and cytotoxicity. 展开更多
关键词 ΓΔT expansion IMMUNOTHERAPY ZOLEDRONATE N-aminobisphosphonates Mevalonate pathway
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From solid to fluid: The possible role of tissue fluidity in mechanical stretch-induced tissue expansion
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作者 Shengzhou Shan Xusong Luo 《Chinese Journal of Plastic and Reconstructive Surgery》 2025年第1期56-58,共3页
Tissue expansion is a widely utilized technique in plastic and reconstructive surgery;however,the biological mechanisms underlying the skin response remain poorly understood.We propose that tissue fluidity,the transit... Tissue expansion is a widely utilized technique in plastic and reconstructive surgery;however,the biological mechanisms underlying the skin response remain poorly understood.We propose that tissue fluidity,the transition of tissue from a solid-like state to a fluid-like state,plays a pivotal role in enabling the reorganization of the epidermal structure and cellular spatial order,which is essential for effective tissue expansion.Drawing parallels between fluidity in materials science and biological systems,we suggest that the fluid-like behavior in the skin may be critical for mechanical adaptability.Understanding the influence of tissue fluidity may open pathways for modulating this process,potentially enhancing tissue expansion efficiency,reducing procedural duration,and improving clinical outcomes.This perspective highlights the importance of investigating the biological dynamics of tissue fluidity and exploring the potential for targeted manipulation of fluidity-related pathways to optimize tissue expansion.Such advancements could profoundly affect regenerative and reconstructive surgical practices. 展开更多
关键词 Tissue expansion Tissue fluidity Mechanical stretch EPIDERMIS
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Multi-dimensional hydrogen bonds regulated emissions of single-molecule system enabling surficial hydrophobicity/hydrophilicity mapping
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作者 Hao Gu Rui Li +6 位作者 Qiuying Li Sheng Lu Yahui Chen Xiaoning Yang Huili Ma Zhijun Xu Xiaoqiang Chen 《Chinese Chemical Letters》 2025年第5期515-520,共6页
Constructing multi-dimensional hydrogen bond(H-bond)regulated single-molecule systems with multiemission remains a challenge.Herein,we report the design of a new excited-state intramolecular proton transfer(ESIPT)feat... Constructing multi-dimensional hydrogen bond(H-bond)regulated single-molecule systems with multiemission remains a challenge.Herein,we report the design of a new excited-state intramolecular proton transfer(ESIPT)featured chromophore(HBT-DPI)that shows flexible emission tunability via the multidimensional regulation of intra-and intermolecular H-bonds.The feature of switchable intramolecular Hbonds is induced via incorporating several hydrogen bond acceptors and donors into one single HBT-DPI molecule,allowing the“turn on/off”of ESIPT process by forming isomers with distinct intramolecular Hbonds configurations.In response to different external H-bonding environments,the obtained four types of crystal/cocrystals vary in the contents of isomers and the molecular packing modes,which are mainly guided by the intermolecular H-bonds,exhibiting non-emissive features or emissions ranging from green to orange.Utilizing the feature of intermolecular H-bond guided molecular packing,we demonstrate the utility of this fluorescent material for visualizing hydrophobic/hydrophilic areas on large-scale heterogeneous surfaces of modified poly(1,1-difluoroethylene)(PVDF)membranes and quantitatively estimating the surface hydrophobicity,providing a new approach for hydrophobicity/hydrophilicity monitoring and measurement.Overall,this study represents a new design strategy for constructing multi-dimensional hydrogen bond regulated ESIPT-based fluorescent materials that enable multiple emissions and unique applications. 展开更多
关键词 multi-dimensional hydrogen bonds Emission regulation Hydrophobicity/hydrophilicity Surficial mapping Excited-state intramolecular proton transfer
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Discussion on Traffic Organization Design for the Expansion and Reconstruction of Highway Interchanges
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作者 Xiaoxi Yang 《Journal of Architectural Research and Development》 2025年第3期58-63,共6页
As a critically important transportation infrastructure in China,highways play a significant role in supporting socio-economic development.However,due to the rapid growth of the current socio-economic landscape and th... As a critically important transportation infrastructure in China,highways play a significant role in supporting socio-economic development.However,due to the rapid growth of the current socio-economic landscape and the dramatic increase in the number of cars,many early-built highways have experienced a surge in traffic volume,making it difficult to meet the growing traffic demand.This has led to various issues such as traffic congestion and inefficient operation.Therefore,it is necessary to expand and reconstruct the highway interchanges,effectively optimizing traffic organization design and significantly improving the overall service level of the highway.This article provides a detailed analysis of the principles and key points of traffic organization design for the expansion and reconstruction of highway interchanges.Additionally,it delves into the design scheme for the traffic organization of these interchanges. 展开更多
关键词 HIGHWAY expansion and reconstruction INTERCHANGE Traffic organization design
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Achieving scalable expansion of therapeutic porcine hepatocytes in vivo through serial transplantation
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作者 Zhiqiang Han Xin Wang +8 位作者 Dawei Yu Jing Wang Ke Sun Siqi Wang Ying Zhang Guihai Feng Wei Li Tang Hai Jilong Ren 《Animal Models and Experimental Medicine》 2025年第7期1337-1344,共8页
The clinical application of hepatocyte transplantation has been significantly hindered by the scarcity of primary hepatocytes and the functional immaturity of in vitro-pro-duced hepatocytes.By performing serial alloge... The clinical application of hepatocyte transplantation has been significantly hindered by the scarcity of primary hepatocytes and the functional immaturity of in vitro-pro-duced hepatocytes.By performing serial allogeneic hepatocyte transplantation in CRISPR/Cas9-mediated Fah-knockout pigs,we successfully achieved large-scale ex-pansion of hepatocytes while maintaining their authentic biological characteristics.Particularly,the established model enables sustained in vivo liver reconstruction,concurrently ameliorating hepatic fibrosis and demonstrating functional microenvi-ronmental remodeling.Moreover,through comprehensive single-cell transcriptomic profiling of 52418 hepatocytes across transplant generations(F0-F2),we discovered that the cellular composition of these transplanted hepatocytes is similar to that of wild-type hepatocytes.The regenerated liver exhibits all six major hepatic cell types identical to the wild-type counterparts,with the characteristic lobular zonation pat-terns well preserved.Our research provides valuable insights into the large-scale expansion of physiologically functional hepatocytes in vivo without compromising their biological properties.This finding holds great promise for advancing the clinical application of human hepatocyte transplantation,potentially offering more effective treatment options for patients with liver diseases. 展开更多
关键词 cellular therapy HEPATOCYTE large-scale expansion regeneration single-cell RNA sequencing
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