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Toeplitz Operators on the Bergman Space of Multi-connected Domains 被引量:3
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作者 于涛 曹广福 《Northeastern Mathematical Journal》 CSCD 2001年第4期487-493,共7页
In this paper, we investigate the Toeplitz operators with positive measure symbols on the Bergman spaces of bounded multi-connected domains and show that a Toeplitz operator is bounded or compact if and only if the sy... In this paper, we investigate the Toeplitz operators with positive measure symbols on the Bergman spaces of bounded multi-connected domains and show that a Toeplitz operator is bounded or compact if and only if the symbol measure is a Carleson or vanishing Carleson measure respectively. 展开更多
关键词 Bergman space Toeplitz operator Carleson measure multi-connected domain
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Viscosity prediction of refining slag based on machine learning with domain knowledge
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作者 Jianhua Chen Yijie Feng +4 位作者 Yixin Zhang Jun Luan Xionggang Lu Zhigang Yu Kuochih Chou 《International Journal of Minerals,Metallurgy and Materials》 2026年第2期555-566,共12页
The viscosity of refining slags plays a critical role in metallurgical processes.However,obtaining accurate viscosity data remains challenging due to the complexities of high-temperature experiments,often relying on e... The viscosity of refining slags plays a critical role in metallurgical processes.However,obtaining accurate viscosity data remains challenging due to the complexities of high-temperature experiments,often relying on empirical models with limited predictive capabilities.This study focuses on the influence of optical basicity on viscosity in CaO-Al_(2)O_(3)-based refining slags,leveraging machine learning to address data scarcity and improve prediction accuracy.An automated framework for algorithm integration,parameter tuning,and evaluation ranking framework(Auto-APE)is employed to develop customized data-driven models for various slag systems,including CaO-Al_(2)O_(3)-SiO_(2),CaO-Al_(2)O_(3)-CaF_(2),CaO-Al_(2)O_(3)-SiO_(2)-MgO,and CaO-Al_(2)O_(3)-SiO_(2)-MgO-CaF_(2).By incorporating optical basicity as a key feature,the models achieve an average validation error of 8.0%to 15.1%,significantly outperforming traditional empirical models.Additionally,symbolic regression is introduced to rapidly construct domain-specific features,such as optical basicity-like descriptors,offering a potential breakthrough in performance prediction for small datasets.This work highlights the critical role of domain-specific knowledge in understanding and predicting viscosity,providing a robust machine learning-based approach for optimizing refining slag properties. 展开更多
关键词 refining slag viscosity prediction machine learning domain knowledge
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FENet:Underwater Image Enhancement via Frequency Domain Enhancement and Edge-Guided Refinement
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作者 Xinwei Zhu Jianxun Zhang Huan Zeng 《Computers, Materials & Continua》 2026年第2期1942-1966,共25页
Underwater images often affect the effectiveness of underwater visual tasks due to problems such as light scattering,color distortion,and detail blurring,limiting their application performance.Existing underwater imag... Underwater images often affect the effectiveness of underwater visual tasks due to problems such as light scattering,color distortion,and detail blurring,limiting their application performance.Existing underwater image enhancement methods,although they can improve the image quality to some extent,often lead to problems such as detail loss and edge blurring.To address these problems,we propose FENet,an efficient underwater image enhancement method.FENet first obtains three different scales of images by image downsampling and then transforms them into the frequency domain to extract the low-frequency and high-frequency spectra,respectively.Then,a distance mask and a mean mask are constructed based on the distance and magnitude mean for enhancing the high-frequency part,thus improving the image details and enhancing the effect by suppressing the noise in the low-frequency part.Affected by the light scattering of underwater images and the fact that some details are lost if they are directly reduced to the spatial domain after the frequency domain operation.For this reason,we propose a multi-stage residual feature aggregation module,which focuses on detail extraction and effectively avoids information loss caused by global enhancement.Finally,we combine the edge guidance strategy to further enhance the edge details of the image.Experimental results indicate that FENet outperforms current state-of-the-art underwater image enhancement methods in quantitative and qualitative evaluations on multiple publicly available datasets. 展开更多
关键词 Detail extraction frequency domain operation edge guidance image enhancement
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EDTM:Efficient Domain Transition for Multi-Source Domain Adaptation
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作者 Mangyu Lee Jaekyun Jeong +2 位作者 Yun Wook Choo Keejun Han Jungeun Kim 《Computer Modeling in Engineering & Sciences》 2026年第2期955-970,共16页
Domain adaptation aims to reduce the distribution gap between the training data(source domain)and the target data.This enables effective predictions even for domains not seen during training.However,most conventional ... Domain adaptation aims to reduce the distribution gap between the training data(source domain)and the target data.This enables effective predictions even for domains not seen during training.However,most conventional domain adaptation methods assume a single source domain,making them less suitable for modern deep learning settings that rely on diverse and large-scale datasets.To address this limitation,recent research has focused on Multi-Source Domain Adaptation(MSDA),which aims to learn effectively from multiple source domains.In this paper,we propose Efficient Domain Transition for Multi-source(EDTM),a novel and efficient framework designed to tackle two major challenges in existing MSDA approaches:(1)integrating knowledge across different source domains and(2)aligning label distributions between source and target domains.EDTM leverages an ensemble-based classifier expert mechanism to enhance the contribution of source domains that are more similar to the target domain.To further stabilize the learning process and improve performance,we incorporate imitation learning into the training of the target model.In addition,Maximum Classifier Discrepancy(MCD)is employed to align class-wise label distributions between the source and target domains.Experiments were conducted using Digits-Five,one of the most representative benchmark datasets for MSDA.The results show that EDTM consistently outperforms existing methods in terms of average classification accuracy.Notably,EDTM achieved significantly higher performance on target domains such as Modified National Institute of Standards and Technolog with blended background images(MNIST-M)and Street View House Numbers(SVHN)datasets,demonstrating enhanced generalization compared to baseline approaches.Furthermore,an ablation study analyzing the contribution of each loss component validated the effectiveness of the framework,highlighting the importance of each module in achieving optimal performance. 展开更多
关键词 Multi-source domain adaptation imitation learning maximum classifier discrepancy ensemble based classifier EDTM
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Gearbox Fault Diagnosis under Varying Operating Conditions through Semi-Supervised Masked Contrastive Learning and Domain Adaptation
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作者 Zhixiang Huang Jun Li 《Computer Modeling in Engineering & Sciences》 2026年第2期448-470,共23页
To address the issue of scarce labeled samples and operational condition variations that degrade the accuracy of fault diagnosis models in variable-condition gearbox fault diagnosis,this paper proposes a semi-supervis... To address the issue of scarce labeled samples and operational condition variations that degrade the accuracy of fault diagnosis models in variable-condition gearbox fault diagnosis,this paper proposes a semi-supervised masked contrastive learning and domain adaptation(SSMCL-DA)method for gearbox fault diagnosis under variable conditions.Initially,during the unsupervised pre-training phase,a dual signal augmentation strategy is devised,which simultaneously applies random masking in the time domain and random scaling in the frequency domain to unlabeled samples,thereby constructing more challenging positive sample pairs to guide the encoder in learning intrinsic features robust to condition variations.Subsequently,a ConvNeXt-Transformer hybrid architecture is employed,integrating the superior local detail modeling capacity of ConvNeXt with the robust global perception capability of Transformer to enhance feature extraction in complex scenarios.Thereafter,a contrastive learning model is constructed with the optimization objective of maximizing feature similarity across different masked instances of the same sample,enabling the extraction of consistent features from multiple masked perspectives and reducing reliance on labeled data.In the final supervised fine-tuning phase,a multi-scale attention mechanism is incorporated for feature rectification,and a domain adaptation module combining Local Maximum Mean Discrepancy(LMMD)with adversarial learning is proposed.This module embodies a dual mechanism:LMMD facilitates fine-grained class-conditional alignment,compelling features of identical fault classes to converge across varying conditions,while the domain discriminator utilizes adversarial training to guide the feature extractor toward learning domain-invariant features.Working in concert,they markedly diminish feature distribution discrepancies induced by changes in load,rotational speed,and other factors,thereby boosting the model’s adaptability to cross-condition scenarios.Experimental evaluations on the WT planetary gearbox dataset and the Case Western Reserve University(CWRU)bearing dataset demonstrate that the SSMCL-DA model effectively identifies multiple fault classes in gearboxes,with diagnostic performance substantially surpassing that of conventional methods.Under cross-condition scenarios,the model attains fault diagnosis accuracies of 99.21%for the WT planetary gearbox and 99.86%for the bearings,respectively.Furthermore,the model exhibits stable generalization capability in cross-device settings. 展开更多
关键词 GEARBOX variable working conditions fault diagnosis semi-supervised masked contrastive learning domain adaptation
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Motion In-Betweening via Frequency-Domain Diffusion Model
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作者 Qiang Zhang Shuo Feng +2 位作者 Shanxiong Chen Teng Wan Ying Qi 《Computers, Materials & Continua》 2026年第1期275-296,共22页
Human motion modeling is a core technology in computer animation,game development,and humancomputer interaction.In particular,generating natural and coherent in-between motion using only the initial and terminal frame... Human motion modeling is a core technology in computer animation,game development,and humancomputer interaction.In particular,generating natural and coherent in-between motion using only the initial and terminal frames remains a fundamental yet unresolved challenge.Existing methods typically rely on dense keyframe inputs or complex prior structures,making it difficult to balance motion quality and plausibility under conditions such as sparse constraints,long-term dependencies,and diverse motion styles.To address this,we propose a motion generation framework based on a frequency-domain diffusion model,which aims to better model complex motion distributions and enhance generation stability under sparse conditions.Our method maps motion sequences to the frequency domain via the Discrete Cosine Transform(DCT),enabling more effective modeling of low-frequency motion structures while suppressing high-frequency noise.A denoising network based on self-attention is introduced to capture long-range temporal dependencies and improve global structural awareness.Additionally,a multi-objective loss function is employed to jointly optimize motion smoothness,pose diversity,and anatomical consistency,enhancing the realism and physical plausibility of the generated sequences.Comparative experiments on the Human3.6M and LaFAN1 datasets demonstrate that our method outperforms state-of-the-art approaches across multiple performance metrics,showing stronger capabilities in generating intermediate motion frames.This research offers a new perspective and methodology for human motion generation and holds promise for applications in character animation,game development,and virtual interaction. 展开更多
关键词 Motion generation diffusion model frequency domain human motion synthesis self-attention network 3D motion interpolation
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Coordination Thermodynamic Control of Magnetic Domain Configuration Evolution toward Low‑Frequency Electromagnetic Attenuation
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作者 Tong Huang Dan Wang +9 位作者 Xue He Zhaobo Feng Zhiqiang Xiong Yuqi Luo Yuhui Peng Guangsheng Luo Xuliang Nie Mingyue Yuan Chongbo Liu Renchao Che 《Nano-Micro Letters》 2026年第3期860-875,共16页
The precise tuning of magnetic nanoparticle size and magnetic domains,thereby shaping magnetic properties.However,the dynamic evolution mechanisms of magnetic domain configurations in relation to electromagnetic(EM)at... The precise tuning of magnetic nanoparticle size and magnetic domains,thereby shaping magnetic properties.However,the dynamic evolution mechanisms of magnetic domain configurations in relation to electromagnetic(EM)attenuation behavior remain poorly understood.To address this gap,a thermodynamically controlled periodic coordination strategy is proposed to achieve precise modulation of magnetic nanoparticle spacing.This approach unveils the evolution of magnetic domain configurations,progressing from individual to coupled and ultimately to crosslinked domain configurations.A unique magnetic coupling phenomenon surpasses the Snoek limit in low-frequency range,which is observed through micromagnetic simulation.The crosslinked magnetic configuration achieves effective low-frequency EM wave absorption at 3.68 GHz,encompassing nearly the entire C-band.This exceptional magnetic interaction significantly enhances radar camouflage and thermal insulation properties.Additionally,a robust gradient metamaterial design extends coverage across the full band(2–40 GHz),effectively mitigating the impact of EM pollution on human health and environment.This comprehensive study elucidates the evolution mechanisms of magnetic domain configurations,addresses gaps in dynamic magnetic modulation,and provides novel insights for the development of high-performance,low-frequency EM wave absorption materials. 展开更多
关键词 Thermodynamically controlled coordination strategy Magnetic domain configuration Low-frequency electromagnetic wave absorption Electrical/magnetic coupling MULTIFUNCTION
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拟连续domain上的广义理想收敛
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作者 王武 谭彬 张舜 《安徽大学学报(自然科学版)》 北大核心 2025年第5期11-18,共8页
在定向完备偏序集中引入了广义理想下极限和广义理想终下界极限的概念,并研究了其与Scott拓扑和Lawson拓扑的关系.主要结果有:(1)在定向完备偏序集上,广义理想下极限拓扑与Scott拓扑一致;(2)广义理想下极限收敛是拓扑的当且仅当定向完... 在定向完备偏序集中引入了广义理想下极限和广义理想终下界极限的概念,并研究了其与Scott拓扑和Lawson拓扑的关系.主要结果有:(1)在定向完备偏序集上,广义理想下极限拓扑与Scott拓扑一致;(2)广义理想下极限收敛是拓扑的当且仅当定向完备偏序集是拟连续domain;(3)在拟连续domain中,广义理想终下界极限拓扑与Lawson拓扑一致,并给出了定向完备偏序集为连续domain的一个充分条件. 展开更多
关键词 拟连续domain 广义理想下极限 广义理想终下界极限 SCOTT拓扑 LAWSON拓扑
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INVERSE PROBLEMS FOR A GENERAL MULTI-CONNECTED BOUNDED DRUM WITH APPLICATIONS IN PHYSICS 被引量:1
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作者 E.M.E.Zayed 《Acta Mathematica Scientia》 SCIE CSCD 2003年第1期104-116,共13页
This paper studies the influence of a finite container on an ideal gas.The trace of the heat kernel (t) =exp, where are the eigenvalues of the negative Laplacian -in Rn(n = 2 or 3), is studied for a general multi-conn... This paper studies the influence of a finite container on an ideal gas.The trace of the heat kernel (t) =exp, where are the eigenvalues of the negative Laplacian -in Rn(n = 2 or 3), is studied for a general multi-connected bounded drum ft which is surrounded by simply connected bounded domains Ωi with smooth boundaries Ωi(i = 1,… ,m) where the Dirichlet, Neumann and Robin boundary conditions on Ωi(i = 1,…,m) are considered. Some geometrical properties of Ω are determined. The thermodynamic quantities for an ideal gas enclosed in Ω are examined by using the asymptotic expansions of (t) for short-time t. It is shown that the ideal gas can not feel the shape of its container Ω, although it can feel some geometrical properties of it. 展开更多
关键词 Inverse problem heat kernel EIGENVALUES an ideal gas multi-connected bounded domain
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Interwell interference model of horizontal wells in shale gas reservoirs based on multi-connected boundary element method
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作者 Yu-Long Zhao Hao-Yan Feng +4 位作者 Cheng-Zhong Bu Li-Sha Zhou Jian-Fa Wu Lie-Hui Zhang Ying-Fang Zhou 《Petroleum Science》 CSCD 2024年第6期4278-4297,共20页
Due to the wide application of closely spaced multi-well horizontal pads for developing unconventional gas reservoirs,interference between wells becomes a significant concern.Communication between wells mainly occurs ... Due to the wide application of closely spaced multi-well horizontal pads for developing unconventional gas reservoirs,interference between wells becomes a significant concern.Communication between wells mainly occurs through natural fractures.However,previous studies have found that interwell communication through natural fractures is varied,and non-communication also appears in the mid and late stages of production due to natural fracture closure.This study proposes a boundary element method for coupling multi-connected regions for the first time.Using this method,we coupled multiple flow fields to establish dual-well models with various connectivity conditions of the stimulated reservoir volume(SRV)region.These models also take into consideration of adsorption and desorption mechanism of natural gas as well as the impact of fracturing fluid retention.The study found that when considering the non-communication of SRV regions between multi-well horizontal pads,the transient behavior of the targeted well exhibits a transitional flow stage occurring before the well interference flow stage.In addition,sensitivity analysis shows that the well spacing and production regime,as well as the connectivity conditions of the SRV region,affect the timing of interwell interference.Meanwhile,the productivity of the two wells,reservoir properties,and fracturing operations affect the intensity of interwell interference. 展开更多
关键词 Interwell interference multi-connected boundary element method Shalegas reservoirs Complex flow mechanisms Transient analysis
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Ferroelectric domain engineering of Lithium niobate 被引量:1
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作者 Jackson J.Chakkoria Aditya Dubey +1 位作者 Arnan Mitchell Andreas Boes 《Opto-Electronic Advances》 2025年第2期46-79,共34页
Lithium niobate(LN)has remained at the forefront of academic research and industrial applications due to its rich material properties,which include second-order nonlinear optic,electro-optic,and piezoelectric properti... Lithium niobate(LN)has remained at the forefront of academic research and industrial applications due to its rich material properties,which include second-order nonlinear optic,electro-optic,and piezoelectric properties.A further aspect of LN’s versatility stems from the ability to engineer ferroelectric domains with micro and even nano-scale precision in LN,which provides an additional degree of freedom to design acoustic and optical devices with improved performance and is only possible in a handful of other materials.In this review paper,we provide an overview of the domain engineering techniques developed for LN,their principles,and the typical domain size and pattern uniformity they provide,which is important for devices that require high-resolution domain patterns with good reproducibility.It also highlights each technique's benefits,limitations,and adaptability for an application,along with possible improvements and future advancement prospects.Further,the review provides a brief overview of domain visualization methods,which is crucial to gain insights into domain quality/shape and explores the adaptability of the proposed domain engineering methodologies for the emerging thin-film lithium niobate on an insulator platform,which creates opportunities for developing the next generation of compact and scalable photonic integrated circuits and high frequency acoustic devices. 展开更多
关键词 lithium niobate FERROELECTRIC domain engineering lithium niobate on insulator domain visualization periodic poling quasi-phase matching acoustic
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Leci:Learnable Evolutionary Category Intermediates for Unsupervised Domain Adaptive Segmentation 被引量:1
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作者 Qiming ZHANG Yufei XU +1 位作者 Jing ZHANG Dacheng TAO 《Artificial Intelligence Science and Engineering》 2025年第1期37-51,共15页
To avoid the laborious annotation process for dense prediction tasks like semantic segmentation,unsupervised domain adaptation(UDA)methods have been proposed to leverage the abundant annotations from a source domain,s... To avoid the laborious annotation process for dense prediction tasks like semantic segmentation,unsupervised domain adaptation(UDA)methods have been proposed to leverage the abundant annotations from a source domain,such as virtual world(e.g.,3D games),and adapt models to the target domain(the real world)by narrowing the domain discrepancies.However,because of the large domain gap,directly aligning two distinct domains without considering the intermediates leads to inefficient alignment and inferior adaptation.To address this issue,we propose a novel learnable evolutionary Category Intermediates(CIs)guided UDA model named Leci,which enables the information transfer between the two domains via two processes,i.e.,Distilling and Blending.Starting from a random initialization,the CIs learn shared category-wise semantics automatically from two domains in the Distilling process.Then,the learned semantics in the CIs are sent back to blend the domain features through a residual attentive fusion(RAF)module,such that the categorywise features of both domains shift towards each other.As the CIs progressively and consistently learn from the varying feature distributions during training,they are evolutionary to guide the model to achieve category-wise feature alignment.Experiments on both GTA5 and SYNTHIA datasets demonstrate Leci's superiority over prior representative methods. 展开更多
关键词 unsupervised domain adaptation semantic segmentation deep learning
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Complex cross-regional landslide susceptibility mapping by multi-source domain transfer learning 被引量:1
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作者 Yan Su Jiayuan Fu +7 位作者 Xiaohe Lai Chuan Lin Lvyun Zhu Xiudong Xie Jun Jiang Yaoxin Chen Jingyu Huang Wenhong Huang 《Geoscience Frontiers》 2025年第4期25-39,共15页
Landslide susceptibility evaluation plays an important role in disaster prevention and reduction.Feature-based transfer learning(TL)is an effective method for solving landslide susceptibility mapping(LSM)in target reg... Landslide susceptibility evaluation plays an important role in disaster prevention and reduction.Feature-based transfer learning(TL)is an effective method for solving landslide susceptibility mapping(LSM)in target regions with no available samples.However,as the study area expands,the distribution of land-slide types and triggering mechanisms becomes more diverse,leading to performance degradation in models relying on landslide evaluation knowledge from a single source domain due to domain feature shift.To address this,this study proposes a Multi-source Domain Adaptation Convolutional Neural Network(MDACNN),which combines the landslide prediction knowledge learned from two source domains to perform cross-regional LSM in complex large-scale areas.The method is validated through case studies in three regions located in southeastern coastal China and compared with single-source domain TL models(TCA-based models).The results demonstrate that MDACNN effectively integrates transfer knowledge from multiple source domains to learn diverse landslide-triggering mechanisms,thereby significantly reducing prediction bias inherent to single-source domain TL models,achieving an average improvement of 16.58%across all metrics.Moreover,the landslide susceptibility maps gener-ated by MDACNN accurately quantify the spatial distribution of landslide risks in the target area,provid-ing a powerful scientific and technological tool for landslide disaster management and prevention. 展开更多
关键词 Landslide susceptibility Deep learning MDACNN Feature domain adaptation Data scarcity
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异源WHy-Domain蛋白的结构与抗逆功能比较分析
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作者 邓云峰 贺小丽 +7 位作者 韦廷舟 赖瑞林 范清锋 张泽颖 代其林 周正富 王劲 江世杰 《分子植物育种》 北大核心 2025年第14期4679-4687,共9页
水胁迫与过敏反应结构域(WHy-Domain)是第5C家族LEA蛋白(LEA5C)包含的一个典型结构域,该WHy-Domain蛋白在细胞抵抗非生物胁迫过程中发挥重要作用。前期研究发现,不同来源的WHy-Domain蛋白序列差异较大,可能具有不同的生物学功能。为探... 水胁迫与过敏反应结构域(WHy-Domain)是第5C家族LEA蛋白(LEA5C)包含的一个典型结构域,该WHy-Domain蛋白在细胞抵抗非生物胁迫过程中发挥重要作用。前期研究发现,不同来源的WHy-Domain蛋白序列差异较大,可能具有不同的生物学功能。为探究不同WHy-Domain蛋白结构和抗逆功能的关系,本研究选择植物、细菌和古菌来源的4个WHy-Domain蛋白,开展了生物信息学分析、重组菌株构建及非生物胁迫表型试验。结果显示,4个WHy-Domain蛋白均具有LEA5C家族蛋白疏水等特性,但氨基酸组成、二级结构等差异较大。异常球菌属DrWHy基因过量表达提高重组大肠杆菌氧化和渗透胁迫抗性;假单胞菌属BnWHy表达提高大肠杆菌的抗氧化能力;古菌AfWHy表达增强重组大肠杆菌耐受氧化、高渗、高温和高盐能力,植物OsWHy表达能够有效增强重组大肠杆菌低温和渗透胁迫抗性。表明结构不同的WHy-Domain蛋白具有不同的非生物胁迫抗性功能。本研究为进一步探讨WHy-Domain蛋白的进化机制提供科学依据,同时也为农业逆境合成生物学研究提供最小元器件。 展开更多
关键词 WHy-domain蛋白 生物信息学分析 重组大肠杆菌 非生物胁迫抗性
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The Characterization of Self-adjoint Domains of Two-interval Odd Order Differential Operators
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作者 WANG Linyu HAO Xiaoling LI Kun 《数学进展》 北大核心 2025年第4期784-802,共19页
In this paper,we give a complete characterization of all self-adjoint domains of odd order differential operators on two intervals.These two intervals with all four endpoints are singular(one endpoint of each interval... In this paper,we give a complete characterization of all self-adjoint domains of odd order differential operators on two intervals.These two intervals with all four endpoints are singular(one endpoint of each interval is singular or all four endpoints are regulars are the special cases).And these extensions yield"new"self-adjoint operators,which involve interactions between the two intervals. 展开更多
关键词 self-adjoint domain odd order differential operator two-interval
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The Paley-Wiener Theorem for General Weighted Hardy Spaces on Tube Domains
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作者 HUANG Yun ZHANG Dawei 《应用数学》 北大核心 2025年第3期841-849,共9页
In this paper,the Paley-Wiener theorem is extended to the analytic function spaces with general weights.We first generalize the theorem to weighted Hardy spaces Hp(0<p<∞)on tube domains by constructing a sequen... In this paper,the Paley-Wiener theorem is extended to the analytic function spaces with general weights.We first generalize the theorem to weighted Hardy spaces Hp(0<p<∞)on tube domains by constructing a sequence of L^(1)functions converging to the given function and verifying their representation in the form of Fourier transform to establish the desired result of the given function.Applying this main result,we further generalize the Paley-Wiener theorem for band-limited functions to the analytic function spaces L^(p)(0<p<∞)with general weights. 展开更多
关键词 Paley-Wiener Theorem Fourier transform Weighted Hardy space Tube domain
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The Citron homology domain of MAP4Ks improves outcomes of traumatic brain injury
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作者 Xiaoling Zhong Wenjiao Tai +4 位作者 Meng-Lu Liu Shuaipeng Ma Tianjin Shen Yuhua Zou Chun-Li Zhang 《Neural Regeneration Research》 SCIE CAS 2025年第11期3233-3244,共12页
The mitogen-activated protein kinase kinase kinase kinases(MAP4Ks)signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following insults.Whether targeting this pathway is beneficial to b... The mitogen-activated protein kinase kinase kinase kinases(MAP4Ks)signaling pathway plays a pivotal role in axonal regrowth and neuronal degeneration following insults.Whether targeting this pathway is beneficial to brain injury remains unclear.In this study,we showed that adeno-associated virus-delivery of the Citron homology domain of MAP4Ks effectively reduces traumatic brain injury-induced reactive gliosis,tauopathy,lesion size,and behavioral deficits.Pharmacological inhibition of MAP4Ks replicated the ameliorative effects observed with expression of the Citron homology domain.Mechanistically,the Citron homology domain acted as a dominant-negative mutant,impeding MAP4K-mediated phosphorylation of the dishevelled proteins and thereby controlling the Wnt/β-catenin pathway.These findings implicate a therapeutic potential of targeting MAP4Ks to alleviate the detrimental effects of traumatic brain injury. 展开更多
关键词 adeno-associated virus Citron homology Citron homology domain gene therapy mitogen-activated protein kinase kinase kinase kinases traumatic brain injury
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Enhanced Piezoelectric Properties of (1-x)(0.8PZT-0.2PZN)-xBZT Ceramics via Phase Boundary and Domain Engineering
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作者 CHEN Xiangjie LI Ling +2 位作者 LEI Tianfu WANG Jiajia WANG Yaojin 《无机材料学报》 北大核心 2025年第6期729-734,共6页
Pb(Zr,Ti)O_(3)-Pb(Zn_(1/3)Nb_(2/3))O_(3) (PZT-PZN) based ceramics, as important piezoelectric materials, have a wide range of applications in fields such as sensors and actuators, thus the optimization of their piezoe... Pb(Zr,Ti)O_(3)-Pb(Zn_(1/3)Nb_(2/3))O_(3) (PZT-PZN) based ceramics, as important piezoelectric materials, have a wide range of applications in fields such as sensors and actuators, thus the optimization of their piezoelectric properties has been a hot research topic. This study investigated the effects of phase boundary engineering and domain engineering on (1-x)[0.8Pb(Zr_(0.5)Ti_(0.5))O_(3)-0.2Pb(Zn_(1/3)Nb_(2/3))O_(3)]-xBi(Zn_(0.5)Ti_(0.5))O_(3) ((1-x)(0.8PZT-0.2PZN)- xBZT) ceramic to obtain excellent piezoelectric properties. The crystal phase structure and microstructure of ceramic samples were characterized. The results showed that all samples had a pure perovskite structure, and the addition of BZT gradually increased the grain size. The addition of BZT caused a phase transition in ceramic samples from the morphotropic phase boundary (MPB) towards the tetragonal phase region, which is crucial for optimizing piezoelectric properties. By adjusting content of BZT and precisely controlling position of the phase boundary, the piezoelectric performance can be optimized. Domain structure is one of the key factors affecting piezoelectric performance. By using domain engineering techniques to optimize grain size and domain size, piezoelectric properties of ceramic samples have been significantly improved. Specifically, excellent piezoelectric properties (piezoelectric constant d_(33)=320 pC/N, electromechanical coupling factor kp=0.44) were obtained simultaneously for x=0.08. Based on experimental results and theoretical analysis, influence mechanisms of phase boundary engineering and domain engineering on piezoelectric properties were explored. The study shows that addition of BZT not only promotes grain growth, but also optimizes the domain structure, enabling the polarization reversal process easier, thereby improving piezoelectric properties. These research results not only provide new ideas for the design of high-performance piezoelectric ceramics, but also lay a theoretical foundation for development of related electronic devices. 展开更多
关键词 phase boundary 0.8PZT-0.2PZN domain engineering piezoelectric property
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From Spatial Domain to Patch-Based Models:A Comprehensive Review and Comparison of Multimodal Medical Image Denoising Algorithms
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作者 Apoorav Sharma Ayush Dogra +2 位作者 Bhawna Goyal Archana Saini Vinay Kukreja 《Computers, Materials & Continua》 2025年第10期367-481,共115页
To enable proper diagnosis of a patient,medical images must demonstrate no presence of noise and artifacts.The major hurdle lies in acquiring these images in such a manner that extraneous variables,causing distortions... To enable proper diagnosis of a patient,medical images must demonstrate no presence of noise and artifacts.The major hurdle lies in acquiring these images in such a manner that extraneous variables,causing distortions in the form of noise and artifacts,are kept to a bare minimum.The unexpected change realized during the acquisition process specifically attacks the integrity of the image’s quality,while indirectly attacking the effectiveness of the diagnostic process.It is thus crucial that this is attended to with maximum efficiency at the level of pertinent expertise.The solution to these challenges presents a complex dilemma at the acquisition stage,where image processing techniques must be adopted.The necessity of this mandatory image pre-processing step underpins the implementation of traditional state-of-the-art methods to create functional and robust denoising or recovery devices.This article hereby provides an extensive systematic review of the above techniques,with the purpose of presenting a systematic evaluation of their effect on medical images under three different distributions of noise,i.e.,Gaussian,Poisson,and Rician.A thorough analysis of these methods is conducted using eight evaluation parameters to highlight the unique features of each method.The covered denoising methods are essential in actual clinical scenarios where the preservation of anatomical details is crucial for accurate and safe diagnosis,such as tumor detection in MRI and vascular imaging in CT. 展开更多
关键词 Image denoising MRI CT spatial domain filters transform domain
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Interaction of major facilitator superfamily domain containing 2A with the blood-brain barrier
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作者 Yilun Ma Taiwei Dong +3 位作者 Fei Luan Juanjuan Yang Feng Miao Peifeng Wei 《Neural Regeneration Research》 SCIE CAS 2025年第8期2133-2152,共20页
The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the bloo... The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the blood-brain barrier remain poorly understood.The major facilitator superfamily domain containing 2A has been identified as a key regulator of blood-brain barrier function.It plays a critical role in promoting and maintaining the formation and functional stability of the blood-brain barrier,in addition to the transport of lipids,such as docosahexaenoic acid,across the blood-brain barrier.Furthermore,an increasing number of studies have suggested that major facilitator superfamily domain containing 2A is involved in the molecular mechanisms of blood-brain barrier dysfunction in a variety of neurological diseases;however,little is known regarding the mechanisms by which major facilitator superfamily domain containing 2A affects the blood-brain barrier.This paper provides a comprehensive and systematic review of the close relationship between major facilitator superfamily domain containing 2A proteins and the blood-brain barrier,including their basic structures and functions,cross-linking between major facilitator superfamily domain containing 2A and the blood-brain barrier,and the in-depth studies on lipid transport and the regulation of blood-brain barrier permeability.This comprehensive systematic review contributes to an in-depth understanding of the important role of major facilitator superfamily domain containing 2A proteins in maintaining the structure and function of the blood-brain barrier and the research progress to date.This will not only help to elucidate the pathogenesis of neurological diseases,improve the accuracy of laboratory diagnosis,and optimize clinical treatment strategies,but it may also play an important role in prognostic monitoring.In addition,the effects of major facilitator superfamily domain containing 2A on blood-brain barrier leakage in various diseases and the research progress on cross-blood-brain barrier drug delivery are summarized.This review may contribute to the development of new approaches for the treatment of neurological diseases. 展开更多
关键词 blood-brain barrier(BBB) CAVEOLIN-1 central nervous system docosahexaenoic acid endothelial cells LYSOPHOSPHATIDYLCHOLINE major facilitator superfamily domain containing 2A(MFSD2A) TRANSCYTOSIS
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