期刊文献+
共找到78,127篇文章
< 1 2 250 >
每页显示 20 50 100
基于UPLC-Orbitrap Fusion Lumos Tribrid-MS的女贞子酒蒸前后血清药物化学对比分析
1
作者 刘昊霖 郑历史 +3 位作者 孙淑仃 赵迪 李焕茹 冯素香 《中华中医药学刊》 北大核心 2026年第1期175-186,I0027,共13页
目的基于超高效液相色谱-四极杆-静电场轨道阱-线性离子阱质谱法(ultra performance liquid chromatography-orbitrap fusion lumos tribrid-mass spectrometry,UPLC-Orbitrap Fusion Lumos Tribrid-MS)对大鼠灌胃女贞子、酒女贞子水提... 目的基于超高效液相色谱-四极杆-静电场轨道阱-线性离子阱质谱法(ultra performance liquid chromatography-orbitrap fusion lumos tribrid-mass spectrometry,UPLC-Orbitrap Fusion Lumos Tribrid-MS)对大鼠灌胃女贞子、酒女贞子水提液后血清中的移行成分进行对比分析。方法雄性Sprague-Dawley(SD)大鼠随机分为空白组、女贞子组(10.8 g·kg^(-1)·d^(-1))和酒女贞子组(10.8 g·kg^(-1)·d^(-1)),每组6只,给药组分别灌胃给予女贞子、酒女贞子水提液,空白组灌胃等体积纯净水,早晚各1次,连续5 d,末次给药1 h后腹主动脉取血,制备血清样品。采用Accucore^(TM) C_(18)(100 mm×2.1 mm,2.6μm)色谱柱,流动相为乙腈(A)-0.1%甲酸水(B),梯度洗脱(0~5 min,95%B→85%B;5~10 min,85%B→73%B;10~24 min,73%B→15%B),流速0.2 mL·min^(-1),进样量5μL,正、负离子模式扫描,扫描范围m/z 120~1200。采用Compound Discoverer 3.3软件,根据质谱数据和相关文献对女贞子、酒女贞子入血原型成分和代谢产物进行分析鉴定;采用多元统计分析方法对比女贞子、酒女贞子含药血清间的差异性成分。结果在给予女贞子水提液大鼠血清中共鉴定得到64个入血成分,包括40个原型成分和24个代谢产物;在给予酒女贞子水提液大鼠血清中共鉴定得到57个入血成分,包括35个原型成分和22个代谢产物。原型成分主要包括苯乙醇苷类、环烯醚萜类、三萜类、黄酮类等,代谢途径主要包括羟基化、甲基化、葡萄糖醛酸化等。根据变量重要性投影(variable importance in projection,VIP)值>1,t检验(Student's t test)结果P<0.05筛选出特女贞苷、女贞苷酸等12个差异性入血成分,其中7个原型成分、5个代谢产物。结论女贞子酒蒸后血清移行成分发生明显改变,可为阐明女贞子、酒女贞子药效物质基础提供理论依据。 展开更多
关键词 女贞子 炮制 血清药物化学 UPLC-Orbitrap fusion Lumos Tribrid-MS 多元统计分析
原文传递
A Synergistic Multi-Attribute Decision-Making Method for Educational Institutions Evaluation Using Similarity Measures of Possibility Pythagorean Fuzzy Hypersoft Sets
2
作者 Khuram Ali Khan Saba Mubeen Ishfaq +1 位作者 Atiqe Ur Rahman Salwa El-Morsy 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期501-530,共30页
Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pP... Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be difficult.The concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such uncertainties.This study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and AND-operations.Some results related to these operations are also modified for pPyFHSS.Additionally,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and results.Lastly,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested system.The algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical models.Similarly,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison. 展开更多
关键词 Hypersoft set Pythagorean fuzzy hypersoft set computational complexity multi-attribute decision-making optimization similarity measures uncertainty
在线阅读 下载PDF
Medical Diagnosis Based on Multi-Attribute Group Decision-Making Using Extension Fuzzy Sets,Aggregation Operators and Basic Uncertainty Information Granule
3
作者 Anastasios Dounis Ioannis Palaiothodoros Anna Panagiotou 《Computer Modeling in Engineering & Sciences》 SCIE EI 2025年第1期759-811,共53页
Accurate medical diagnosis,which involves identifying diseases based on patient symptoms,is often hindered by uncertainties in data interpretation and retrieval.Advanced fuzzy set theories have emerged as effective to... Accurate medical diagnosis,which involves identifying diseases based on patient symptoms,is often hindered by uncertainties in data interpretation and retrieval.Advanced fuzzy set theories have emerged as effective tools to address these challenges.In this paper,new mathematical approaches for handling uncertainty in medical diagnosis are introduced using q-rung orthopair fuzzy sets(q-ROFS)and interval-valued q-rung orthopair fuzzy sets(IVq-ROFS).Three aggregation operators are proposed in our methodologies:the q-ROF weighted averaging(q-ROFWA),the q-ROF weighted geometric(q-ROFWG),and the q-ROF weighted neutrality averaging(qROFWNA),which enhance decision-making under uncertainty.These operators are paired with ranking methods such as the similarity measure,score function,and inverse score function to improve the accuracy of disease identification.Additionally,the impact of varying q-rung values is explored through a sensitivity analysis,extending the analysis beyond the typical maximum value of 3.The Basic Uncertain Information(BUI)method is employed to simulate expert opinions,and aggregation operators are used to combine these opinions in a group decisionmaking context.Our results provide a comprehensive comparison of methodologies,highlighting their strengths and limitations in diagnosing diseases based on uncertain patient data. 展开更多
关键词 Medical diagnosis multi-attribute group decision-making(MAGDM) q-ROFS IVq-ROFS BUI aggregation operators similarity measures inverse score function
在线阅读 下载PDF
Cultural Landscape Zoning of Traditional Villages in Southwest Hubei Based on Multi-attribute Weighted k-modes Clustering
4
作者 Yiran GUO Wei XU Jie XU 《Meteorological and Environmental Research》 2025年第3期33-39,43,共8页
Cultural landscape zoning research of traditional villages is the basic premise for carrying out overall protection and regional development.Through the clustering algorithm,cultural area zoning research of traditiona... Cultural landscape zoning research of traditional villages is the basic premise for carrying out overall protection and regional development.Through the clustering algorithm,cultural area zoning research of traditional villages can provide objective basis for its overall protection and development.Based on the field research,drawing on the theory of cultural landscape,southwest Hubei is taken as the research object,and the index system of cultural landscape type division of traditional villages is constructed from three levels of culture,geography and village carrier.Adopting the multi-attribute weighted k-modes clustering algorithm,92 traditional villages in southwest Hubei are divided into three major types,which are the western Tujia cultural characteristic area,the southern Tujia-Miao cultural penetration area,and the northern multi-ethnic cultural mixed area,and the characteristics of each area are summarized.The regional characteristics of traditional villages in southwest Hubei at the cultural landscape level are analysed from a macro point of view,which provides a reference for more objective cognition of the distribution law of traditional villages in southwest Hubei,and carrying out the contiguous protection of traditional villages. 展开更多
关键词 multi-attribute weighted k-modes clustering Cultural landscape Southwest Hubei Traditional village
在线阅读 下载PDF
Subgraph Matching on Multi-Attributed Graphs Based on Contrastive Learning
5
作者 LIU Bozhi FANG Xiu +1 位作者 SUN Guohao LU Jinhu 《Journal of Donghua University(English Edition)》 2025年第5期523-533,共11页
Graphs have been widely used in fields ranging from chemical informatics to social network analysis.Graph-related problems become increasingly significant,with subgraph matching standing out as one of the most challen... Graphs have been widely used in fields ranging from chemical informatics to social network analysis.Graph-related problems become increasingly significant,with subgraph matching standing out as one of the most challenging tasks.The goal of subgraph matching is to find all subgraphs in the data graph that are isomorphic to the query graph.Traditional methods mostly rely on search strategies with high computational complexity and are hard to apply to large-scale real datasets.With the advent of graph neural networks(GNNs),researchers have turned to GNNs to address subgraph matching problems.However,the multi-attributed features on nodes and edges are overlooked during the learning of graphs,which causes inaccurate results in real-world scenarios.To tackle this problem,we propose a novel model called subgraph matching on multi-attributed graph network(SGMAN).SGMAN first utilizes improved line graphs to capture node and edge features.Then,SGMAN integrates GNN and contrastive learning(CL)to derive graph representation embeddings and calculate the matching matrix to represent the matching results.We conduct experiments on public datasets,and the results affirm the superior performance of our model. 展开更多
关键词 subgraph matching graph neural network(GNN) multi-attributed graph contrastive learning(CL)
在线阅读 下载PDF
Effect of Addition of Er-TiB_(2)Dual-Phase Nanoparticles on Strength-Ductility of Al-Mn-Mg-Sc-Zr Alloy Prepared by Laser Powder Bed Fusion
6
作者 Li Suli Zhang Yanze +5 位作者 Yang Mengjia Zhang Longbo Xie Qidong Yang Laixia MaoFeng Chen Zhen 《稀有金属材料与工程》 北大核心 2026年第1期9-17,共9页
A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5w... A dual-phase synergistic enhancement method was adopted to strengthen the Al-Mn-Mg-Sc-Zr alloy fabricated by laser powder bed fusion(LPBF)by leveraging the unique advantages of Er and TiB_(2).Spherical powders of 0.5wt%Er-1wt%TiB_(2)/Al-Mn-Mg-Sc-Zr nanocomposite were prepared using vacuum homogenization technique,and the density of samples prepared through the LPBF process reached 99.8%.The strengthening and toughening mechanisms of Er-TiB_(2)were investigated.The results show that Al_(3)Er diffraction peaks are detected by X-ray diffraction analysis,and texture strength decreases according to electron backscatter diffraction results.The added Er and TiB_(2)nano-reinforcing phases act as heterogeneous nucleation sites during the LPBF forming process,hindering grain growth and effectively refining the grains.After incorporating the Er-TiB_(2)dual-phase nano-reinforcing phases,the tensile strength and elongation at break of the LPBF-deposited samples reach 550 MPa and 18.7%,which are 13.4%and 26.4%higher than those of the matrix material,respectively. 展开更多
关键词 Al-Mn-Mg-Sc-Zr alloy laser powder bed fusion nano-reinforcing phase synergistic enhancement
原文传递
Bearing Fault Diagnosis Based on Multimodal Fusion GRU and Swin-Transformer
7
作者 Yingyong Zou Yu Zhang +2 位作者 Long Li Tao Liu Xingkui Zhang 《Computers, Materials & Continua》 2026年第1期1587-1610,共24页
Fault diagnosis of rolling bearings is crucial for ensuring the stable operation of mechanical equipment and production safety in industrial environments.However,due to the nonlinearity and non-stationarity of collect... Fault diagnosis of rolling bearings is crucial for ensuring the stable operation of mechanical equipment and production safety in industrial environments.However,due to the nonlinearity and non-stationarity of collected vibration signals,single-modal methods struggle to capture fault features fully.This paper proposes a rolling bearing fault diagnosis method based on multi-modal information fusion.The method first employs the Hippopotamus Optimization Algorithm(HO)to optimize the number of modes in Variational Mode Decomposition(VMD)to achieve optimal modal decomposition performance.It combines Convolutional Neural Networks(CNN)and Gated Recurrent Units(GRU)to extract temporal features from one-dimensional time-series signals.Meanwhile,the Markovian Transition Field(MTF)is used to transform one-dimensional signals into two-dimensional images for spatial feature mining.Through visualization techniques,the effectiveness of generated images from different parameter combinations is compared to determine the optimal parameter configuration.A multi-modal network(GSTCN)is constructed by integrating Swin-Transformer and the Convolutional Block Attention Module(CBAM),where the attention module is utilized to enhance fault features.Finally,the fault features extracted from different modalities are deeply fused and fed into a fully connected layer to complete fault classification.Experimental results show that the GSTCN model achieves an average diagnostic accuracy of 99.5%across three datasets,significantly outperforming existing comparison methods.This demonstrates that the proposed model has high diagnostic precision and good generalization ability,providing an efficient and reliable solution for rolling bearing fault diagnosis. 展开更多
关键词 MULTI-MODAL GRU swin-transformer CBAM CNN feature fusion
在线阅读 下载PDF
Trajectory and influencing factors of changes in anxiety and depression in elderly patients after lumbar interbody fusion
8
作者 Xiao-Feng Liu Yan-Hua Wu +4 位作者 Guang-Xi Huang Bin Yu Hui-Juan Xu Meng-Hua Qiu Lin Kang 《World Journal of Psychiatry》 2026年第1期312-321,共10页
BACKGROUND Lumbar interbody fusion(LIF)is the primary treatment for lumbar degenerative diseases.Elderly patients are prone to anxiety and depression after undergoing surgery,which affects their postoperative recovery... BACKGROUND Lumbar interbody fusion(LIF)is the primary treatment for lumbar degenerative diseases.Elderly patients are prone to anxiety and depression after undergoing surgery,which affects their postoperative recovery speed and quality of life.Effective prevention of anxiety and depression in elderly patients has become an urgent problem.AIM To investigate the trajectory of anxiety and depression levels in elderly patients after LIF,and the influencing factors.METHODS Random sampling was used to select 239 elderly patients who underwent LIF from January 2020 to December 2024 in Shenzhen Pingle Orthopedic Hospital.General information and surgery-related indices were recorded,and participants completed measures of psychological status,lumbar spine dysfunction,and quality of life.A latent class growth model was used to analyze the post-LIF trajectory of anxiety and depression levels,and unordered multi-categorical logistic regression was used to analyze the influencing factors.RESULTS Three trajectories of change in anxiety level were identified:Increasing anxiety(n=26,10.88%),decreasing anxiety(n=27,11.30%),and stable anxiety(n=186,77.82%).Likewise,three trajectories of change in depression level were identified:Increasing depression(n=30,12.55%),decreasing depression(n=26,10.88%),and stable depression(n=183,76.57%).Regression analysis showed that having no partner,female sex,elevated Oswestry dysfunction index(ODI)scores,and reduced 36-Item Short Form Health Survey scores all contributed to increased anxiety levels,whereas female sex,postoperative opioid use,and elevated ODI scores all contributed to increased depression levels.CONCLUSION During clinical observation,combining factors to predict anxiety and depression in post-LIF elderly patients enables timely intervention,quickens recovery,and enhances quality of life. 展开更多
关键词 Lumbar interbody fusion Elderly patients ANXIETY DEPRESSION Trajectory of change Influencing factors
暂未订购
Cephalomedullary fusion nails for treatment of infected stemmed revision total knee arthroplasty:Four case reports
9
作者 Gregory M Georgiadis Isaac A Arefi +3 位作者 Summer M Drees Ajay Nair Drew Wagner Austin C Lawrence 《World Journal of Orthopedics》 2026年第1期189-196,共8页
BACKGROUND Salvage of the infected long stem revision total knee arthroplasty is challenging due to the presence of well-fixed ingrown or cemented stems.Reconstructive options are limited.Above knee amputation(AKA)is ... BACKGROUND Salvage of the infected long stem revision total knee arthroplasty is challenging due to the presence of well-fixed ingrown or cemented stems.Reconstructive options are limited.Above knee amputation(AKA)is often recommended.We present a surgical technique that was successfully used on four such patients to convert them to a knee fusion(KF)using a cephalomedullary nail.CASE SUMMARY Four patients with infected long stem revision knee replacements that refused AKA had a single stage removal of their infected revision total knee followed by a KF.They were all treated with a statically locked antegrade cephalomedullary fusion nail,augmented with antibiotic impregnated bone cement.All patients had successful limb salvage and were ambulatory with assistive devices at the time of last follow-up.All were infection free at an average follow-up of 25.5 months(range 16-31).CONCLUSION Single stage cephalomedullary nailing can result in a successful KF in patients with infected long stem revision total knees. 展开更多
关键词 Knee fusion Knee arthrodesis Intramedullary nail Cephalomedullary nail Total knee infection Case report
暂未订购
Identification of small impact craters in Chang’e-4 landing areas using a new multi-scale fusion crater detection algorithm
10
作者 FangChao Liu HuiWen Liu +7 位作者 Li Zhang Jian Chen DiJun Guo Bo Li ChangQing Liu ZongCheng Ling Ying-Bo Lu JunSheng Yao 《Earth and Planetary Physics》 2026年第1期92-104,共13页
Impact craters are important for understanding the evolution of lunar geologic and surface erosion rates,among other functions.However,the morphological characteristics of these micro impact craters are not obvious an... Impact craters are important for understanding the evolution of lunar geologic and surface erosion rates,among other functions.However,the morphological characteristics of these micro impact craters are not obvious and they are numerous,resulting in low detection accuracy by deep learning models.Therefore,we proposed a new multi-scale fusion crater detection algorithm(MSF-CDA)based on the YOLO11 to improve the accuracy of lunar impact crater detection,especially for small craters with a diameter of<1 km.Using the images taken by the LROC(Lunar Reconnaissance Orbiter Camera)at the Chang’e-4(CE-4)landing area,we constructed three separate datasets for craters with diameters of 0-70 m,70-140 m,and>140 m.We then trained three submodels separately with these three datasets.Additionally,we designed a slicing-amplifying-slicing strategy to enhance the ability to extract features from small craters.To handle redundant predictions,we proposed a new Non-Maximum Suppression with Area Filtering method to fuse the results in overlapping targets within the multi-scale submodels.Finally,our new MSF-CDA method achieved high detection performance,with the Precision,Recall,and F1 score having values of 0.991,0.987,and 0.989,respectively,perfectly addressing the problems induced by the lesser features and sample imbalance of small craters.Our MSF-CDA can provide strong data support for more in-depth study of the geological evolution of the lunar surface and finer geological age estimations.This strategy can also be used to detect other small objects with lesser features and sample imbalance problems.We detected approximately 500,000 impact craters in an area of approximately 214 km2 around the CE-4 landing area.By statistically analyzing the new data,we updated the distribution function of the number and diameter of impact craters.Finally,we identified the most suitable lighting conditions for detecting impact crater targets by analyzing the effect of different lighting conditions on the detection accuracy. 展开更多
关键词 impact craters Chang’e-4 landing area multi-scale automatic detection YOLO11 fusion algorithm
在线阅读 下载PDF
Multi-attribute decision-making based on subjective and objective integrated eigenvector method 被引量:12
11
作者 龚艳冰 陈森发 《Journal of Southeast University(English Edition)》 EI CAS 2007年第1期144-147,共4页
An integrated approach is proposed to investigate the fuzzy multi-attribute decision-making (MADM) problems, where subjective preferences are expressed by a pairwise comparison matrix on the relative weights of attr... An integrated approach is proposed to investigate the fuzzy multi-attribute decision-making (MADM) problems, where subjective preferences are expressed by a pairwise comparison matrix on the relative weights of attributes and objective information is expressed by a decision matrix. An eigenvector method integrated the subjective fuzzy preference matrix and objective information is proposed. Two linear programming models based on subjective and objective information are introduced to assess the relative importance weights of attributes in an MADM problem. The simple additive weighting method is utilized to aggregate the decision information, and then all the alternatives are ranked. Finally, a numerical example is given to show the feasibility and effectiveness of the method. The result shows that it is easier than other methods of integrating subjective and objective information. 展开更多
关键词 multi-attribute decision-making eigenvector method alternative ranking
在线阅读 下载PDF
APPROACH FOR FUZZY MULTI-ATTRIBUTE DECISION-MAKING WITH FUZZY COMPLEMENTARY PREFERENCE RELATION ON ALTERNATIVES 被引量:2
12
作者 周宏安 刘三阳 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2007年第1期74-79,共6页
In presented fuzzy multi-attribute decision-making (FMADM) problems, the information about attribute weights is interval numbers and the decision maker (DM) has fuzzy complementary preference relation on alternati... In presented fuzzy multi-attribute decision-making (FMADM) problems, the information about attribute weights is interval numbers and the decision maker (DM) has fuzzy complementary preference relation on alternatives. Firstly, the decision-making information based on the subjective preference information in the form of the fuzzy complementary judgment matrix is uniform by using a translation function. Then an objective programming model is established. Attribute weights are obtained by solving the model, thus the fuzzy overall values of alternatives are derived by using the additive weighting method. Secondly, the ranking approach of alternatives is proposed based on the degree of similarity between the fuzzy positive ideal solution of alternatives (FPISA) and the fuzzy overall values. The method can sufficiently utilize the objective information of alternatives and meet the subjective requirements of the DM as much as possible. It is easy to be operated and implemented on a computer. Finally, the proposed method is applied to the project evaluation in the venture investment. 展开更多
关键词 fuzzy multi-attribute decision-making objective programming WEIGHT similarity degree PRIORITY
在线阅读 下载PDF
Multi-attribute Decision Making Method Based on the Attribute Difference Degree and Its Application in Rice Breeding
13
作者 邹永红 谭建林 《Agricultural Science & Technology》 CAS 2011年第8期1093-1095,1099,共4页
[Objective]The aim was to establish a multi-attribute decision making method and introduce its application in rice breeding.[Method]Based on the defined closeness degree among attributes,the difference degrees among a... [Objective]The aim was to establish a multi-attribute decision making method and introduce its application in rice breeding.[Method]Based on the defined closeness degree among attributes,the difference degrees among attributes were discussed.Furthermore,the weights of attributes were determined based on the difference degrees among the attributes.[Result]A multi-attribute decision making method based on difference degrees among attributes was established,the feasibility of applying it in rice breeding was also analyzed.[Conclusion]This study enriched the methods to determine attribute weights in multi-attribute decision making and provided the necessary theoretical support for selecting rice varieties scientifically and rationally. 展开更多
关键词 multi-attribute decision making Closeness degree WEIGHT PRIORITIZATION Rice breeding
在线阅读 下载PDF
基于UPLC-Orbitrap Fusion Lumos Tribrid-MS、网络药理学与实验验证的正骨紫金丸活性成分及作用机制研究
14
作者 冯志毅 孙淑仃 +3 位作者 郑历史 孙琪 刘泽 冯素香 《中国现代应用药学》 北大核心 2025年第21期3704-3716,共13页
目的基于UPLC-Orbitrap Fusion Lumos Tribrid-MS联合网络药理学与实验验证预测正骨紫金丸活血化瘀的活性成分及其作用机制。方法首先,采用UPLC-Orbitrap Fusion Lumos Tribrid-MS快速表征正骨紫金丸中的化学成分;其次,通过网络药理学... 目的基于UPLC-Orbitrap Fusion Lumos Tribrid-MS联合网络药理学与实验验证预测正骨紫金丸活血化瘀的活性成分及其作用机制。方法首先,采用UPLC-Orbitrap Fusion Lumos Tribrid-MS快速表征正骨紫金丸中的化学成分;其次,通过网络药理学的研究方法构建“药物-成分-靶点”网络,获取关键靶点及主要活性成分,结合String平台与CytoScape软件构建蛋白质-蛋白质相互作用(protein-protein interaction,PPI)网络,通过MateScape数据库富集分析通路,利用DiscoVery Studio 4.5软件进行分子对接验证;最后,建立急性软组织损伤动物模型,以急性软组织损伤评分与全血黏度为药效学指标开展药效学研究。结果正骨紫金丸中共鉴定出包括黄酮类、生物碱类、有机酸类和香豆素类等化合物67个,其中大黄素、藁本内酯、肉桂酸、水杨酸、芦荟大黄素可能为正骨紫金丸活血化瘀的主要活性成分。PPI网络拓扑分析得到TNF、ALB、AKT1等26个核心靶点,KEGG富集分析表明正骨紫金丸主要通过调控TNF、PI3K-Akt、NF-κB等信号通路发挥活血化瘀作用,分子对接结果显示正骨紫金丸主要活性成分与关键靶点结合良好,药效学结果表明正骨紫金丸可显著降低急性软组织损伤大鼠的全血黏度。结论本研究明确了正骨紫金丸活血化瘀的活性成分和作用机制,同时表明其可能通过作用于多靶点、多通路整体调节,共同发挥活血化瘀作用,为其后续深入研究提供参考。 展开更多
关键词 正骨紫金丸 UPLC-Orbitrap fusion Lumos Tribrid-MS 成分分析 网络药理学 活血化瘀
原文传递
Two-phase TOPSIS of uncertain multi-attribute group decision-making 被引量:17
15
作者 Wenkun Zhou Wenchun Jiang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2010年第3期423-430,共8页
To solve the uncertain multi-attribute group decision-making of unknown attribute weights,three optimal models are built to decide the corresponding ideal solution weights,standard deviation weights and mean deviation... To solve the uncertain multi-attribute group decision-making of unknown attribute weights,three optimal models are built to decide the corresponding ideal solution weights,standard deviation weights and mean deviation weights.The comprehensive attribute weights are gotten through the product of the above three kinds of weights.And each decision maker's weighted decision matrices are also received by using the integrated attribute weights.The closeness degrees are also gotten by use of technique for order preference by similarity to ideal solution(TOPSIS) through dealing with the weighted decision matrices.At the same time the group decision matrix and weighted group decision matrix are gotten by using each decision-maker's closeness degree to every project.Then the vertical TOPSIS method is used to calculate the closeness degree of each project.So these projects can be ranked according to their values of the closeness degree.The process of the method is also given step by step.Finally,a numerical example demonstrates the feasibility and effectiveness of the approach. 展开更多
关键词 multi-attribute decision-making uncertain numbers TOPSIS WEIGHTS the closeness degree.
在线阅读 下载PDF
An Improved Method Based on TODIM and TOPSIS for Multi-Attribute Decision-Making with Multi-Valued Neutrosophic Sets 被引量:4
16
作者 Dongsheng Xu Lijuan Peng 《Computer Modeling in Engineering & Sciences》 SCIE EI 2021年第11期907-926,共20页
Due to the complexity of decision-making problems and the subjectivity of decision-makers in practical application,it is necessary to adopt different forms of information expression according to the actual situation o... Due to the complexity of decision-making problems and the subjectivity of decision-makers in practical application,it is necessary to adopt different forms of information expression according to the actual situation of specific decision-making problems and choose the best method to solve them.Multi-valued neutrosophic set,as an extension of neutrosophic set,can more effectively and accurately describe incomplete,uncertain or inconsistent information.TODIM and TOPSIS methods are two commonly used multi-attribute decision-making methods,each of which has its advantages and disadvantages.This paper proposes a new method based on TODIM and TOPSIS to solve multi-attribute decision-making problems under multi-valued neutrosophic environment.After introducing the related theory of multi-valued neutrosophic set and the traditional TODIM and TOPSIS methods,the new method based on a combination of TODIM and TOPSIS methods is described.And then,two illustrative examples proved the feasibility and validity of the proposed method.Finally,the result has been compared with some existing methods under the same examples and the proposed method’s superiority has been proved.This paper studies this kind of decision-making problem from algorithm idea,algorithm steps and decision-making influencing factors. 展开更多
关键词 Multi-valued neutrosophic set TODIM TOPSIS multi-attribute decision-making
在线阅读 下载PDF
Novel combinatorial algorithm for the problems of fuzzy grey multi-attribute group decision making 被引量:13
17
作者 Rao Congjun Xiao Xinping Peng Jin 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第4期774-780,共7页
To study the fuzzy and grey information in the problems of multi-attribute group decision making, the basic concepts of both fuzzy grey numbers and grey interval numbers are given firstly, then a new model of fuzzy gr... To study the fuzzy and grey information in the problems of multi-attribute group decision making, the basic concepts of both fuzzy grey numbers and grey interval numbers are given firstly, then a new model of fuzzy grey multi-attribute group decision making based on the theories of fuzzy mathematics and grey system is presented. Furthermore, the grey interval relative degree and deviation degree is defined, and both the optimistic algorithm of the grey interval relational degree and the algorithm of deviation degree minimization for solving this new model are also given. Finally, a decision making example to demonstrate the feasibility and rationality of this new method is given, and the results by using these two algorithms are uniform. 展开更多
关键词 multi-attribute group decision making fuzzy grey number grey interval relational degree deviation degree
在线阅读 下载PDF
Multi-attributed decision making for mining methods based on grey system and interval numbers 被引量:8
18
作者 刘浪 陈建宏 +1 位作者 王革民 劳德正 《Journal of Central South University》 SCIE EI CAS 2013年第4期1029-1033,共5页
In the case of unknown weights, theories of multi-attributed decision making based on interval numbers and grey related analysis were used to optimize mining methods. As the representative of independence for the indi... In the case of unknown weights, theories of multi-attributed decision making based on interval numbers and grey related analysis were used to optimize mining methods. As the representative of independence for the indicator, the smaller the correlation of indicators is, the greater the weight is. Hence, the weights of interval numbers of indicators were determined by using correlation coefficient. Relative closeness based on positive and negative ideal methods was calculated by introducing distance between interval numbers, which made decision making more rational and comprehensive. A new method of ranking interval numbers based on normal distribution was proposed for the optimization of mining methods, whose basic properties were discussed. Finally, the feasibility and effectiveness of this method were verified by theories and practice. 展开更多
关键词 mining method interval number multi-attributed decision making grey related analysis correlation coefficient normaldistribution RANKING
在线阅读 下载PDF
A decision support system for satellite layout integrating multi-objective optimization and multi-attribute decision making 被引量:3
19
作者 LIANG Yan’gang QIN Zheng 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2019年第3期535-544,共10页
A decision support system, including a multi-objective optimization framework and a multi-attribute decision making approach is proposed for satellite equipment layout. Firstly, given three objectives (to minimize the... A decision support system, including a multi-objective optimization framework and a multi-attribute decision making approach is proposed for satellite equipment layout. Firstly, given three objectives (to minimize the C.G. offset, the cross moments of inertia and the space debris impact risk), we develop a threedimensional layout optimization model. Unlike most of the previous works just focusing on mass characteristics of the system, a space debris impact risk index is developed. Secondly, we develop an efficient optimization framework for the integration of computer-aided design (CAD) software as well as the optimization algorithm to obtain the Pareto front of the layout optimization problem. Thirdly, after obtaining the candidate solutions, we present a multi-attribute decision making approach, which integrates the smart Pareto filter and the correlation coefficient and standard deviation (CCSD) method to select the best tradeoff solutions on the optimal Pareto fronts. Finally, the framework and the decision making approach are applied to a case study of a satellite platform. 展开更多
关键词 layout OPTIMIZATION SATELLITE MULTI-OBJECTIVE OPTIMIZATION PARETO FRONT multi-attribute decision making
在线阅读 下载PDF
Multi-attribute decision making method for air target threat evaluation based on intuitionistic fuzzy sets 被引量:47
20
作者 Yongjie XU Yongchun Wang Xudong Miu 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2012年第6期891-897,共7页
The function of the air target threat evaluation(TE)is the foundation for weapons allocation and senor resources management within the surface air defense.The multi-attribute evaluation methodology is utilized to addr... The function of the air target threat evaluation(TE)is the foundation for weapons allocation and senor resources management within the surface air defense.The multi-attribute evaluation methodology is utilized to address the issue of the TE in which the tactic features of the detected target are treated as evaluation attributes.Meanwhile,the intuitionistic fuzzy set(IFS)is employed to deal with information uncertainty in the TE process.Furthermore,on the basis of the entropy weight and inclusion-comparison probability,a hybrid TE method is developed.In order to accommodate the demands of naturalistic decision making,the proposed method allows air defense commanders to express their intuitive opinions besides incorporating into the threat features of the detected target.An illustrative example is provided to indicate the feasibility and advantage of the proposed method. 展开更多
关键词 threat evaluation(TE) intuitionistic fuzzy set(IFS) multi-attribute evaluation intuitive opinions entropy weight inclusion-comparison probability(ICP).
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部