The data describing of the light scattering intensity relaxation above the glass transition temperature by boron oxide obtained by using of the temperature jump methods are presented. It is found that the stabilizatio...The data describing of the light scattering intensity relaxation above the glass transition temperature by boron oxide obtained by using of the temperature jump methods are presented. It is found that the stabilization of the glass at 220℃ resulted in increasing of the anisotropic intensity at the same time the isotropic intensity is not practically unchangeable. It is shown that after the temperature jump to 330℃the intensity is characterized by the formation of a maximum. This effect is in compliance with the results obtained for the other oxide glasses. It is established that characteristic time of the relaxation of the maximum height is about two orders of magnitude more than the structural relaxation time for this temperature.展开更多
The complexes formed by the interaction of human serum albumin and ampicillin sodium in aqueous solutions were investigated at 25 ± 0.1℃, ionic strength I = 0.085 mol·kg-1, pH 4.9, 5.8 and 7.4. The results ...The complexes formed by the interaction of human serum albumin and ampicillin sodium in aqueous solutions were investigated at 25 ± 0.1℃, ionic strength I = 0.085 mol·kg-1, pH 4.9, 5.8 and 7.4. The results of static light scattering have suggested that at pH 7.4, 5.8, 4.9, the molecular weight of the protein/drug complexes is 210,000 g·mol-1, 418,000 g·mol-1, 448,000 g·mol-1, re- spectively. The z-average root-mean-square radius of gyration and the second virial coefficients de- crease with pH decreasing. Dynamic light scattering provides information on diffusion coefficient and particle distributions of protein/drug complexes under different conditions, which suggests a broad hydrodynamic diameter range of scatters. The diffusion coefficients of the systems change with am- picillin sodium concentration and pH changing.展开更多
文摘The data describing of the light scattering intensity relaxation above the glass transition temperature by boron oxide obtained by using of the temperature jump methods are presented. It is found that the stabilization of the glass at 220℃ resulted in increasing of the anisotropic intensity at the same time the isotropic intensity is not practically unchangeable. It is shown that after the temperature jump to 330℃the intensity is characterized by the formation of a maximum. This effect is in compliance with the results obtained for the other oxide glasses. It is established that characteristic time of the relaxation of the maximum height is about two orders of magnitude more than the structural relaxation time for this temperature.
基金This work was supported by the National Natural Science Foundation of China (Grant No.20275014).
文摘The complexes formed by the interaction of human serum albumin and ampicillin sodium in aqueous solutions were investigated at 25 ± 0.1℃, ionic strength I = 0.085 mol·kg-1, pH 4.9, 5.8 and 7.4. The results of static light scattering have suggested that at pH 7.4, 5.8, 4.9, the molecular weight of the protein/drug complexes is 210,000 g·mol-1, 418,000 g·mol-1, 448,000 g·mol-1, re- spectively. The z-average root-mean-square radius of gyration and the second virial coefficients de- crease with pH decreasing. Dynamic light scattering provides information on diffusion coefficient and particle distributions of protein/drug complexes under different conditions, which suggests a broad hydrodynamic diameter range of scatters. The diffusion coefficients of the systems change with am- picillin sodium concentration and pH changing.
