Objectives:24-h movement behaviors(24-HMB),encompassing physical activity,sedentary behavior,and sleep duration,are increasingly regarded as interrelated and important factors for mental health.However,evidence on the...Objectives:24-h movement behaviors(24-HMB),encompassing physical activity,sedentary behavior,and sleep duration,are increasingly regarded as interrelated and important factors for mental health.However,evidence on the comprehensive association of these behaviors with mental health in adults with diabetes in developing countries remains scarce.This study examined the association between 24-HMB guidelines and psychological health among adults with diabetes in developing countries.Methods:Data were retrieved from the World Health Organization’s study on Global Aging and Adult Health Survey dataset.Adults(N=1905)diagnosed with diabetes from five low-and middle-income countries were included.The exposure of interest was adherence to 24-HMB guidelines,depression,cognition,and quality of life(QoL).Multiple logistic and multiple linear regression analyses were used to examine the association between meeting 24-HMB guidelines and depression,cognition,and QoL,respectively.Results:This cross-sectional study revealed that 28.61%complied with all three 24-HMB guidelines.Diabetic patients who met more numbers of 24-HMB guidelines had lower depression risk(OR=0.74,95%CI:0.61 to 0.91,p=0.004),greater cognition(β=0.42,95%CI:0.25 to 0.60,p<0.001),and QoL(β=1.30,95%CI:1.04 to 1.55,p<0.001)with the non-compliant population.For specific combinations,meeting all three guidelines were significantly associated with lower odds of depression,improved cognitive function,and enhanced QoL(all p<0.001).Conclusion:These findings support that meeting 24-HMB guidelines in a single or combined movement behaviors was significantly related to reduced risk of depression,enhanced cognitive function,and improved QoL among individuals with diabetes.展开更多
Purpose.This study aimed to examine the levels and correlates of 24-h movement behaviors(i.e.,physical activity,sedentary time,and sleep),and different patterns of these behaviors in a nationally representative sample...Purpose.This study aimed to examine the levels and correlates of 24-h movement behaviors(i.e.,physical activity,sedentary time,and sleep),and different patterns of these behaviors in a nationally representative sample of South Koreans aged 12 years and older.This study also aimed to examine the sociodemographic correlates of 24?h movement behaviors stratified by age groups.Methods.Self-reported,repeated cross-sectional data from 10,708 participants in the 2014 and 2015 Korea National Health and Nutrition Examination surveys were used.Key variables included moderate-to-vigorous intensity physical activity,muscular strengthening exercises,walking,active transportation,sedentary time,and sleep.Sociodemographic variables included age,sex,household income,area of residence,and education level.Descriptive statistics by sex and age as well as general linear models by age group were performed.Results.The proportions of individuals meeting the moderate-to-vigorous intensity physical activity,muscular strengthening exercises,and sleep guidelines were,respectively,21.6%,22.1%,and 32.5%in male youth;6.9%,4.5%,and 22.8%in female youth;55.5%,30.8%,and 54.0%in male adults;48.8%,14.4%,and 57.6%in female adults;44.0%,30.6%,and 45.5%in male older adults;and 29.5%,8.9%,and 37.3%in female older adults.The proportions of individuals showing the most ideal combinations of 24-h movement behaviors were only 3.2%in youth,0.4%in adults,and 0 in older adults.Universally,older age,female sex,or living in metro Seoul were associated with unfavorable patterns of 24-h movement behaviors across different age groups.However,the associations of income and education with movement behaviors were mixed across age groups.Conclusion.Overall,the proportion of South Koreans with a healthy 24-h movement behavior pattern is low.The sociodemographic correlates of different types of 24-h movement behaviors should be considered when designing targeted interventions for the promotion of healthy active living for South Koreans.展开更多
Purpose:The purpose of this study was to examine the associations between adherence to the 24-Hour Movement Guidelines and all-cause and cause-specific mortality in a large Spanish prospective cohort.Methods:We analyz...Purpose:The purpose of this study was to examine the associations between adherence to the 24-Hour Movement Guidelines and all-cause and cause-specific mortality in a large Spanish prospective cohort.Methods:We analyzed data from 14,288 participants of the Seguimiento Universidad de Navarra(SUN)Project,followed for a mean of 12.8 years(mean baseline age=38.3 years;60.1%women).Data were collected at baseline and through biennial follow-up questionnaires(up to 10 waves,depending on year of entry).The participants self-reported 24-h movement behaviors at baseline and were categorized based on the number of guidelines met(0-3).Behaviors were assessed at baseline only;changes in adherence during follow-up were not accounted for.Cox proportional hazards models were used to estimate hazard ratios(HRs)for all-cause and cause-specific mortality,adjusting for sociodemographic,lifestyle,and clinical covariates.Results:Meeting a greater number of 24-Hour Movement Guidelines at baseline was associated with a progressively lower risk of all-cause mortality.Compared with those meeting none,the multivariable-adjusted HRs were 0.52(95%confidence interval(95%CI):0.33-0.82)for meeting 1 guideline,0.47(95%CI:0.30-0.73)for meeting 2 guidelines,and 0.44(95%CI:0.28-0.71)for meeting all 3 guidelines.Only adherence to the physical activity guidelines was independently associated with a significantly lower mortality risk(HR=0.70;95%CI:0.55-0.89).A reduced risk was also observed for cancer and other-cause mortality among those meeting 2 or more guidelines.Conclusion:Adherence to the 24-Hour Movement Guidelines at baseline,particularly physical activity,was associated with a lower risk of mortality.Promoting an integrated approach to movement behaviors may be an effective strategy for improving population health and longevity.展开更多
The impact of underwater bubbles on solid surfaces with a gradient wettability is important for fundamental science and technological applications. Despite progress in the translational motion of underwater bubbles on...The impact of underwater bubbles on solid surfaces with a gradient wettability is important for fundamental science and technological applications. Despite progress in the translational motion of underwater bubbles on asymmetric surface, a fundamental dynamic understanding of asymmetrical bounce behavior of the underwater bubble needs to be further improved.Herein, we investigate asymmetrical bounce of underwater bubbles after impacting the wettability gradient copper mesh surface.Asymmetrical bounce of the underwater bubble on the wettability gradient mesh(WGM) surface is composed by asymmetrical spread in the spread process and asymmetrical recoil in the recoil process, which induce the unidirectional movement behavior.Additionally, effective bubble-size manipulation can be easily implemented due to different volumes of bubbles remaining at different locations of WGM surface. We envision that this work will provide a new understanding of asymmetrical bounce behavior of the underwater bubble on the wettability gradient surface, and propose a novel and feasible strategy for constructing the underwater bubble manipulation system.展开更多
Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which inc...Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which include sleep,sedentary behavior(SED),and physical activity,underscore the inherent connections between different daily activities and the comprehensive impact of overall movement patterns on health.Evidence suggested that modifying patterns of 24-hour movement behaviors can aid in preventing and attenuating the progression of NCDs.This study systematically delineated the concept,evolution,analytical methods,and intrinsic associations of 24-hour movement behaviors,emphasizing their pivotal role in the prevention and management of NCDs such as obesity,mental disorders,cardiovascular diseases,diabetes,and renal diseases.Future research endeavors should focus on refining methodologies,broadening study populations,developing research tools,and exploring precise intervention strategies and interdisciplinary approaches to comprehensively enhance the effectiveness of NCDs prevention and management from a temporal perspective.Such efforts are poised to provide substantive guidance and support for public health practices.展开更多
It is well-known that not meeting the 24-hours(h)movement guidelines,including insufficient physical activity(PA),excessive sedentary behavior(SB),inadequate sleep duration,and their combinations,are independent risk ...It is well-known that not meeting the 24-hours(h)movement guidelines,including insufficient physical activity(PA),excessive sedentary behavior(SB),inadequate sleep duration,and their combinations,are independent risk factors for noncommunicable diseases(NCDs).The prevalence of not meeting the guidelines is high across the world,especially in China where has one of the largest population.Some studies have estimated the economic cost of insufficient PA in China,which is useful to guide policymakers to develop and implement effective health actions.However,several research gaps should be discussed and addressed for better evidence base and decision making.This commentary aims to provide a research insight into gaps and recommendations related to the analysis of economic cost of not meeting the 24-h movement guidelines.Some major research gaps can be indicated,including less research attention on excessive SB and inadequate sleep,limited evidence regarding NCDs associated with not meeting all 24-h movement guidelines considered in economic cost analysis,absence of evidence on estimated cost of not meeting the guidelines,and the adherence to methodological guide.Future research is required to address the gaps to guide effective health policy development in China.We hope that this commentary can play an important role in updating research evidence and advancing policy practice.展开更多
Little is known about differences in physical activity among children from urban and rural areas in low-to middleincome countries and some previous investigations revealed disparities in physical activity levels among...Little is known about differences in physical activity among children from urban and rural areas in low-to middleincome countries and some previous investigations revealed disparities in physical activity levels among children and adolescents residing in urban and rural environments.We aimed to:(i)assess the proportion of preschoolaged children(3.0-4.9 years)meeting the global movement guidelines,(ii)evaluate the feasibility of the methods for the SUNRISE study,(iii)examine gender-and urban-rural differences in health and behavior outcomes.Urban and rural location was based on national classifications.Physical activity(waist-worn ActiGraph);sleep duration,screen time and movement behaviors;Gross and fine motor skills(Lower body strength and mobility,Supine-Timed up and go[S-TUG],One-leg standing balance test,hand grip dynamometer,9-hole pegboard test);and executive functions(visual-spatial working memory and inhibition)were assessed in 112 preschoolers(n=50 boys,33 urban),(n=62 girls,41 urban).The results showed that only 18% of children met all movement guidelines,with 53% and 41%meeting the recommendations for sedentary screen time and total physical activity,respectively.A large proportion of children(81%)met the recommended sleep duration of 10-13 hours(h)per day.There is a clear need to promote healthy movement behaviours among preschool-aged children through targeted interventions that address their unique challenges related to gender and urban/rural residence.展开更多
Idiopathic rapid eye movement sleep behavior disorder(iRBD) is often a precursor to neurodegenerative disease. However, voxel-based morphological studies evaluating structural abnormalities in the brains of iRBD patie...Idiopathic rapid eye movement sleep behavior disorder(iRBD) is often a precursor to neurodegenerative disease. However, voxel-based morphological studies evaluating structural abnormalities in the brains of iRBD patients are relatively rare. This study aimed to explore cerebral structural alterations using magnetic resonance imaging and to determine their association with clinical parameters in iRBD patients. Brain structural T1-weighted MRI scans were acquired from 19 polysomnogram-confirmed iRBD patients(male:female 16:3; mean age 66.6 ± 7.0 years) and 20 age-matched healthy controls(male:female 5:15; mean age 63.7 ± 5.9 years). Gray matter volume(GMV) data were analyzed based on Statistical Parametric Mapping 8, using a voxel-based morphometry method and two-sample t-test and multiple regression analysis. Compared with controls, iRBD patients had increased GMV in the middle temporal gyrus and cerebellar posterior lobe, but decreased GMV in the Rolandic operculum, postcentral gyrus, insular lobe, cingulate gyrus, precuneus, rectus gyrus, and superior frontal gyrus. iRBD duration was positively correlated with GMV in the precuneus, cuneus, superior parietal gyrus, postcentral gyrus, posterior cingulate gyrus, hippocampus, lingual gyrus, middle occipital gyrus, middle temporal gyrus, and cerebellum posterior lobe. Furthermore, phasic chin electromyographic activity was positively correlated with GMV in the hippocampus, precuneus, fusiform gyrus, precentral gyrus, superior frontal gyrus, cuneus, inferior parietal lobule, angular gyrus, superior parietal gyrus, paracentral lobule, and cerebellar posterior lobe. There were no significant negative correlations of brain GMV with disease duration or electromyographic activity in iRBD patients. These findings expand the spectrum of known gray matter modifications in iRBD patients and provide evidence of a correlation between brain dysfunction and clinical manifestations in such patients. The protocol was approved by the Ethics Committee of Huashan Hospital(approval No. KY2013-336) on January 6, 2014. This trial was registered in the ISRCTN registry(ISRCTN18238599).展开更多
Rapid eye movement(REM)sleep behavior disorder(RBD)is a parasomnia that is featured by elevated motor behaviors and dream enactments during REM sleep.Clinical observations show that RBD bears significant relevance wit...Rapid eye movement(REM)sleep behavior disorder(RBD)is a parasomnia that is featured by elevated motor behaviors and dream enactments during REM sleep.Clinical observations show that RBD bears significant relevance with several synucleinopathies such as Lewy body dementia and Parkinson disease(PD),and often develops prior to their diagnosis.Being a potential biomarker of PD,investigating the relationship of RBD symptoms and their emergence in developing PD would provide insight intoits pathogenesis.Here,in a chronic model of PD,rats with daily rotenone treatment exhibited key RBD features,including elevated sleep muscle tone,sleep fragmentation and EEG slowing at different time points.Based on detectedearly alpha synuclein aggregation and neural apoptosis in the sublaterodorsal tegmental nucleus(SLD),an area known to promote REM sleep and maintain sleep muscle atonia,the possible involvement of SLD glutamatergic neurons was interrogated.Via chemogenetic activation of SLD glutamatergic neurons,key RBD symptoms and EEG slowing in REM sleep were alleviated.These results are consistent with a progressive degeneration in REM sleep promoting pathways.Our findings provide a foundation for further studies into RBD and its relationship to neurodegenerative diseases.展开更多
Background:New research suggests that the composition(mix)of movement behaviors within a 24-h period may have important implications for health across the lifespan.Consistent with this integrated movement behavior par...Background:New research suggests that the composition(mix)of movement behaviors within a 24-h period may have important implications for health across the lifespan.Consistent with this integrated movement behavior paradigm,a number of countries across the world have developed and released 24-h movement guidelines for specific age groups.The purpose of this systematic review was to examine the associations between the 24-h time-use composition of movement behaviors,or adherence to 24-h movement guidelines,and multiple health indicators across the lifespan.Methods:Five online databases(PsycINFO,PubMed,SPORTDiscus,Web of Science,and Ovid MEDLINE)were searched for relevant peer-reviewed studies published between January 2015 and January 2020 that met the a priori inclusion criteria,with no study design limits.The methodological quality of research evidence for each individual study and for each health indicator was assessed by using a modified version of the Downs and Black checklist.Results:A total of 51 studies from 20 different countries met the inclusion criteria.A total of 31 studies examined adherence(meeting vs.not meeting)to 24-h movement guidelines,and 20 studies used compositional analyses to explore the 24-h time-use composition of movement behaviors.Findings indicated that meeting the 24-h movement guidelines were(1)not associated with adiposity among toddlers,(2)favorably associated with health-related quality of life,social-cognitive development,and behavioral and emotional problems among preschoolers,(3)favorably associated with global cognition,health-related quality of life,and healthy dietary patterns in children,and(4)favorably associated with adiposity,fitness,and cardiometabolic,mental,social,and emotional health among children and youth.Significant associations were also found between the composition of 24-h movement behaviors and indicators of(1)adiposity and bone and skeletal health among preschoolers,(2)health-related quality of life among children,(3)adiposity,fitness,and cardiometabolic,social,and emotional health among children and youth,(4)cardiometabolic health in adults,(5)adiposity and fitness among adults and older adults,and(6)mental health and risk of mortality among older adults.The quality of the available evidence ranged from poor to good.Conclusion:The current evidence indicates that the composition of movement behaviors within a 24-h period may have important implications for health at all ages and that meeting the current 24-h movement guidelines is associated with a number of desirable health indicators in children and youth.Future studies should employ longitudinal and experimental designs,include valid and reliable measures of 24-h movement behaviors,and examine a wide array of health indicators across all age groups.Such studies would confirm the results from the primarily cross-sectional evidence drawn from studies included in our review and further advance our understanding of the relationships between 24-h movement behaviors and health.展开更多
Background:Meeting the 24-Hour Movement Guidelines(physical activity,screen time,and sleep duration) has been associated with positive health indicators.However,there are no previous meta-analyses that have examined t...Background:Meeting the 24-Hour Movement Guidelines(physical activity,screen time,and sleep duration) has been associated with positive health indicators.However,there are no previous meta-analyses that have examined the overall adherence to the 24-Hour Movement Guidelines from pre-school to adolescence across the world.Therefore,the main purpose of this systematic review and meta-analysis was to examine the overall(non)adherence to the 24-Hour Movement Guidelines among preschoolers,children,and adolescents worldwide.Methods:Four electronic databases(MEDLINE,Scopus,Web of Science,and Cochrane Database of Systematic Reviews) were searched for quantitative studies published in Spanish and English between January 2016 and May 2021.Studies that were conducted with apparently healthy participants and reported the overall(non)adherence to the 24-Hour Movement Guidelines in preschoolers and/or children and/or adolescents were included.Results:Sixty-three studies comprising 387,437 individuals(51% girls) aged 3-18 years from 23 countries were included.Overall,7.12%(95%confidence interval(95%CI):6.45%-7.78%) of youth met all three 24-Hour Movement Guidelines,and 19.21%(95%CI:16.73%-21.69%)met none of the 3 recommendations.Concerning sex,adherence to all recommendations was significantly lower in girls(3.75%,95%CI:3.23%-4.27%) than in boys(6.89%,95%CI:5.89%-7.89%)(p <0.001).However,there were no sex differences regarding adherence to any of the 3 individual recommendations(girls,15.66%,95%CI:8.40%-22.92%;boys,12.95%,95%CI:6.57%-19.33%).In terms of age group,adherence to the 3 recommendations was 11.26%(95%CI:8.68%-13.84%),10.31%(95%CI:7.49%-13.12%),and 2.68%(95%CI:1.78%-3.58%) in preschoolers,children,and adolescents,respectively.Conversely,8.81%(95%CI:5.97%-11.64%) of preschoolers,15.57%(95%CI:11.60%-19.54%) of children,and 28.59%(95%CI:22.42%-34.75%) of adolescents did not meet any of the recommendations.South America was the region with the lowest adherence(all:2.93%;none:31.72%).Overall adherence to the 24-Hour Movement Guidelines was positively related to country Human Development Index(β=-0.37,95%CI:-0.65 to-0.09;p=0.010).Conclusion:Most young people fail to meet the three 24-Hour Movement Guidelines,particularly adolescents,girls,and those who are from countries with a lower Human Development Index.Moreover,1 in 5 young people did not meet any of these recommendations.Therefore,these results highlight the need to develop age-and sex-specific strategies to promote these movement behaviors from the early stages of life.展开更多
Background:Emerging adulthood is a pivotal life stage,presenting significant psychological and social changes,such as decreased sociability,depression,and other mental health problems.Previous studies have associated ...Background:Emerging adulthood is a pivotal life stage,presenting significant psychological and social changes,such as decreased sociability,depression,and other mental health problems.Previous studies have associated these changes with an unhealthy lifestyle.The 24-h movement guidelines for healthy lifestyles have been developed to promote appropriate health behaviors and improve individual wellness.However,the relationship between adherence to the 24-h movement guidelines and different characteristics of Chinese emerging adults is yet to be explored.This cross-sectional study aimed to investigate the association between adherence to the 24-h movement guidelines and four characteristics(self-exploration,instability,possibilities,and responsibility)of Chinese emerging adults.Methods:Overall,1,510 Chinese emerging adults aged 18–29 years were included in this study.Each participant completed a self-administered questionnaire that included questions on adherence to the 24-h movement guidelines(physical activity,sedentary behavior,and sleep)and the inventory of dimensions of emerging adulthood.Multivariable logistic regression analysis was employed to investigate the associations between adherence to the 24-h movement guidelines and each of the four characteristics.Results:The proportion of participants who adhered to the 24-h movement guidelines was 31.72%.Multiple regression analysis revealed a significantly negative relationship between adhering to more guidelines and instability(β=−0.51,p<0.001).A statistically significant association was observed between instability and meeting only sedentary behavior(β=−1.27,95%confidence interval[CI]:[−2.32,−0.24],p=0.02),sedentary behavior+sleep(β=−1.30,95%CI:[−2.24,−0.35],p<0.01),and physical activity+sedentary behavior(β=−1.08,95%CI:[1.94,−0.21],p=0.02)guidelines.Further,positive and significant associations were observed between possibilities and meeting the guidelines for only physical activity(β=0.70,95%CI:[0.14,1.27),p=0.01),only sleep(β=0.61,95%CI:[0.01,1.21],p=0.04),physical activity+sedentary behavior(β=0.56,95%CI:[0.04,1.07),p=0.01),and physical activity+sleep(β=0.76,95%CI:[0.23,1.27],p=0.01).Conclusions:These findings suggest that adherence to the 24-h movement guidelines was associated with instability in Chinese emerging adults.Future studies are warranted to verify our findings to highlight the importance of maintaining a heath lifestyle to promote health in emerging adulthood.展开更多
Insufficient physical activity(PA),prolonged sedentary behavior(SB)and inadequate sleep(SLP)are detrimental factors to population health.To address health issues caused by insufficient PA,excessive SB and poor SLP,the...Insufficient physical activity(PA),prolonged sedentary behavior(SB)and inadequate sleep(SLP)are detrimental factors to population health.To address health issues caused by insufficient PA,excessive SB and poor SLP,the World Health Organization(WHO)updated PA and SB guidelines for all populations aged from 5 years to 65 years and older in 2020.For children under 5 years old,the WHO issued the first global guidelines for PA,SB and SLP(collectively refer to movement behaviors)in April 2019.The guidelines applied a holistic approach to promote health behaviors,filling the gap of no comprehensive global movement guidelines for young children.Although the guidelines for young children offer guidance for health promotion,some research and practice implications and other issues should be mentioned.This commentary includes considerations for the importance of the WHO guidelines for younger children,critical analysis of evidence for developing the guidelines,and recommendations for future research and practice.The aim of this paper is to further advance health research in younger populations.展开更多
文摘Objectives:24-h movement behaviors(24-HMB),encompassing physical activity,sedentary behavior,and sleep duration,are increasingly regarded as interrelated and important factors for mental health.However,evidence on the comprehensive association of these behaviors with mental health in adults with diabetes in developing countries remains scarce.This study examined the association between 24-HMB guidelines and psychological health among adults with diabetes in developing countries.Methods:Data were retrieved from the World Health Organization’s study on Global Aging and Adult Health Survey dataset.Adults(N=1905)diagnosed with diabetes from five low-and middle-income countries were included.The exposure of interest was adherence to 24-HMB guidelines,depression,cognition,and quality of life(QoL).Multiple logistic and multiple linear regression analyses were used to examine the association between meeting 24-HMB guidelines and depression,cognition,and QoL,respectively.Results:This cross-sectional study revealed that 28.61%complied with all three 24-HMB guidelines.Diabetic patients who met more numbers of 24-HMB guidelines had lower depression risk(OR=0.74,95%CI:0.61 to 0.91,p=0.004),greater cognition(β=0.42,95%CI:0.25 to 0.60,p<0.001),and QoL(β=1.30,95%CI:1.04 to 1.55,p<0.001)with the non-compliant population.For specific combinations,meeting all three guidelines were significantly associated with lower odds of depression,improved cognitive function,and enhanced QoL(all p<0.001).Conclusion:These findings support that meeting 24-HMB guidelines in a single or combined movement behaviors was significantly related to reduced risk of depression,enhanced cognitive function,and improved QoL among individuals with diabetes.
文摘Purpose.This study aimed to examine the levels and correlates of 24-h movement behaviors(i.e.,physical activity,sedentary time,and sleep),and different patterns of these behaviors in a nationally representative sample of South Koreans aged 12 years and older.This study also aimed to examine the sociodemographic correlates of 24?h movement behaviors stratified by age groups.Methods.Self-reported,repeated cross-sectional data from 10,708 participants in the 2014 and 2015 Korea National Health and Nutrition Examination surveys were used.Key variables included moderate-to-vigorous intensity physical activity,muscular strengthening exercises,walking,active transportation,sedentary time,and sleep.Sociodemographic variables included age,sex,household income,area of residence,and education level.Descriptive statistics by sex and age as well as general linear models by age group were performed.Results.The proportions of individuals meeting the moderate-to-vigorous intensity physical activity,muscular strengthening exercises,and sleep guidelines were,respectively,21.6%,22.1%,and 32.5%in male youth;6.9%,4.5%,and 22.8%in female youth;55.5%,30.8%,and 54.0%in male adults;48.8%,14.4%,and 57.6%in female adults;44.0%,30.6%,and 45.5%in male older adults;and 29.5%,8.9%,and 37.3%in female older adults.The proportions of individuals showing the most ideal combinations of 24-h movement behaviors were only 3.2%in youth,0.4%in adults,and 0 in older adults.Universally,older age,female sex,or living in metro Seoul were associated with unfavorable patterns of 24-h movement behaviors across different age groups.However,the associations of income and education with movement behaviors were mixed across age groups.Conclusion.Overall,the proportion of South Koreans with a healthy 24-h movement behavior pattern is low.The sociodemographic correlates of different types of 24-h movement behaviors should be considered when designing targeted interventions for the promotion of healthy active living for South Koreans.
文摘Purpose:The purpose of this study was to examine the associations between adherence to the 24-Hour Movement Guidelines and all-cause and cause-specific mortality in a large Spanish prospective cohort.Methods:We analyzed data from 14,288 participants of the Seguimiento Universidad de Navarra(SUN)Project,followed for a mean of 12.8 years(mean baseline age=38.3 years;60.1%women).Data were collected at baseline and through biennial follow-up questionnaires(up to 10 waves,depending on year of entry).The participants self-reported 24-h movement behaviors at baseline and were categorized based on the number of guidelines met(0-3).Behaviors were assessed at baseline only;changes in adherence during follow-up were not accounted for.Cox proportional hazards models were used to estimate hazard ratios(HRs)for all-cause and cause-specific mortality,adjusting for sociodemographic,lifestyle,and clinical covariates.Results:Meeting a greater number of 24-Hour Movement Guidelines at baseline was associated with a progressively lower risk of all-cause mortality.Compared with those meeting none,the multivariable-adjusted HRs were 0.52(95%confidence interval(95%CI):0.33-0.82)for meeting 1 guideline,0.47(95%CI:0.30-0.73)for meeting 2 guidelines,and 0.44(95%CI:0.28-0.71)for meeting all 3 guidelines.Only adherence to the physical activity guidelines was independently associated with a significantly lower mortality risk(HR=0.70;95%CI:0.55-0.89).A reduced risk was also observed for cancer and other-cause mortality among those meeting 2 or more guidelines.Conclusion:Adherence to the 24-Hour Movement Guidelines at baseline,particularly physical activity,was associated with a lower risk of mortality.Promoting an integrated approach to movement behaviors may be an effective strategy for improving population health and longevity.
基金supported by the China Postdoctoral Science Foundation (2021TQ0023, 2022TQ0022, 2022M720012)the National Natural Science Foundation of China (52303143, 22005015,22105014)+5 种基金the National Key R&D Program of China (2019YFB1309702)Beijing Young Talent Support ProgramTianmushan Laboratory Research Project (TK2023C018)Beijing Nova Program (20220484213)the 111Projectthe Fundamental Research Funds for the Central Universities。
文摘The impact of underwater bubbles on solid surfaces with a gradient wettability is important for fundamental science and technological applications. Despite progress in the translational motion of underwater bubbles on asymmetric surface, a fundamental dynamic understanding of asymmetrical bounce behavior of the underwater bubble needs to be further improved.Herein, we investigate asymmetrical bounce of underwater bubbles after impacting the wettability gradient copper mesh surface.Asymmetrical bounce of the underwater bubble on the wettability gradient mesh(WGM) surface is composed by asymmetrical spread in the spread process and asymmetrical recoil in the recoil process, which induce the unidirectional movement behavior.Additionally, effective bubble-size manipulation can be easily implemented due to different volumes of bubbles remaining at different locations of WGM surface. We envision that this work will provide a new understanding of asymmetrical bounce behavior of the underwater bubble on the wettability gradient surface, and propose a novel and feasible strategy for constructing the underwater bubble manipulation system.
基金supported by two grants from the Philosophy and Social Science Foundation of Hunan Province(23YBQ027)the Education Department of Hunan Province(HNJG-2022-0483).
文摘Chronic non-communicable diseases(NCDs)represent a significant impediment to improve life expectancy and remain a focal point in global public health and disease prevention efforts.24-hour movement behaviors,which include sleep,sedentary behavior(SED),and physical activity,underscore the inherent connections between different daily activities and the comprehensive impact of overall movement patterns on health.Evidence suggested that modifying patterns of 24-hour movement behaviors can aid in preventing and attenuating the progression of NCDs.This study systematically delineated the concept,evolution,analytical methods,and intrinsic associations of 24-hour movement behaviors,emphasizing their pivotal role in the prevention and management of NCDs such as obesity,mental disorders,cardiovascular diseases,diabetes,and renal diseases.Future research endeavors should focus on refining methodologies,broadening study populations,developing research tools,and exploring precise intervention strategies and interdisciplinary approaches to comprehensively enhance the effectiveness of NCDs prevention and management from a temporal perspective.Such efforts are poised to provide substantive guidance and support for public health practices.
文摘It is well-known that not meeting the 24-hours(h)movement guidelines,including insufficient physical activity(PA),excessive sedentary behavior(SB),inadequate sleep duration,and their combinations,are independent risk factors for noncommunicable diseases(NCDs).The prevalence of not meeting the guidelines is high across the world,especially in China where has one of the largest population.Some studies have estimated the economic cost of insufficient PA in China,which is useful to guide policymakers to develop and implement effective health actions.However,several research gaps should be discussed and addressed for better evidence base and decision making.This commentary aims to provide a research insight into gaps and recommendations related to the analysis of economic cost of not meeting the 24-h movement guidelines.Some major research gaps can be indicated,including less research attention on excessive SB and inadequate sleep,limited evidence regarding NCDs associated with not meeting all 24-h movement guidelines considered in economic cost analysis,absence of evidence on estimated cost of not meeting the guidelines,and the adherence to methodological guide.Future research is required to address the gaps to guide effective health policy development in China.We hope that this commentary can play an important role in updating research evidence and advancing policy practice.
基金the“Ministry of Higher Education and Scientific Research,Tunis,Tunisia”for financial support.
文摘Little is known about differences in physical activity among children from urban and rural areas in low-to middleincome countries and some previous investigations revealed disparities in physical activity levels among children and adolescents residing in urban and rural environments.We aimed to:(i)assess the proportion of preschoolaged children(3.0-4.9 years)meeting the global movement guidelines,(ii)evaluate the feasibility of the methods for the SUNRISE study,(iii)examine gender-and urban-rural differences in health and behavior outcomes.Urban and rural location was based on national classifications.Physical activity(waist-worn ActiGraph);sleep duration,screen time and movement behaviors;Gross and fine motor skills(Lower body strength and mobility,Supine-Timed up and go[S-TUG],One-leg standing balance test,hand grip dynamometer,9-hole pegboard test);and executive functions(visual-spatial working memory and inhibition)were assessed in 112 preschoolers(n=50 boys,33 urban),(n=62 girls,41 urban).The results showed that only 18% of children met all movement guidelines,with 53% and 41%meeting the recommendations for sedentary screen time and total physical activity,respectively.A large proportion of children(81%)met the recommended sleep duration of 10-13 hours(h)per day.There is a clear need to promote healthy movement behaviours among preschool-aged children through targeted interventions that address their unique challenges related to gender and urban/rural residence.
基金supported by the China-US Biomedical Collaborative Research Program,No.81361120393(to CTZ)the National Natural Science Foundation of China,No.81401135(to PW),81671239(to CTZ)the Shanghai Sailing Program,No.18YF1403100(to JJG)
文摘Idiopathic rapid eye movement sleep behavior disorder(iRBD) is often a precursor to neurodegenerative disease. However, voxel-based morphological studies evaluating structural abnormalities in the brains of iRBD patients are relatively rare. This study aimed to explore cerebral structural alterations using magnetic resonance imaging and to determine their association with clinical parameters in iRBD patients. Brain structural T1-weighted MRI scans were acquired from 19 polysomnogram-confirmed iRBD patients(male:female 16:3; mean age 66.6 ± 7.0 years) and 20 age-matched healthy controls(male:female 5:15; mean age 63.7 ± 5.9 years). Gray matter volume(GMV) data were analyzed based on Statistical Parametric Mapping 8, using a voxel-based morphometry method and two-sample t-test and multiple regression analysis. Compared with controls, iRBD patients had increased GMV in the middle temporal gyrus and cerebellar posterior lobe, but decreased GMV in the Rolandic operculum, postcentral gyrus, insular lobe, cingulate gyrus, precuneus, rectus gyrus, and superior frontal gyrus. iRBD duration was positively correlated with GMV in the precuneus, cuneus, superior parietal gyrus, postcentral gyrus, posterior cingulate gyrus, hippocampus, lingual gyrus, middle occipital gyrus, middle temporal gyrus, and cerebellum posterior lobe. Furthermore, phasic chin electromyographic activity was positively correlated with GMV in the hippocampus, precuneus, fusiform gyrus, precentral gyrus, superior frontal gyrus, cuneus, inferior parietal lobule, angular gyrus, superior parietal gyrus, paracentral lobule, and cerebellar posterior lobe. There were no significant negative correlations of brain GMV with disease duration or electromyographic activity in iRBD patients. These findings expand the spectrum of known gray matter modifications in iRBD patients and provide evidence of a correlation between brain dysfunction and clinical manifestations in such patients. The protocol was approved by the Ethics Committee of Huashan Hospital(approval No. KY2013-336) on January 6, 2014. This trial was registered in the ISRCTN registry(ISRCTN18238599).
基金The project supported by the HKGRCGRF gran(t14111715)
文摘Rapid eye movement(REM)sleep behavior disorder(RBD)is a parasomnia that is featured by elevated motor behaviors and dream enactments during REM sleep.Clinical observations show that RBD bears significant relevance with several synucleinopathies such as Lewy body dementia and Parkinson disease(PD),and often develops prior to their diagnosis.Being a potential biomarker of PD,investigating the relationship of RBD symptoms and their emergence in developing PD would provide insight intoits pathogenesis.Here,in a chronic model of PD,rats with daily rotenone treatment exhibited key RBD features,including elevated sleep muscle tone,sleep fragmentation and EEG slowing at different time points.Based on detectedearly alpha synuclein aggregation and neural apoptosis in the sublaterodorsal tegmental nucleus(SLD),an area known to promote REM sleep and maintain sleep muscle atonia,the possible involvement of SLD glutamatergic neurons was interrogated.Via chemogenetic activation of SLD glutamatergic neurons,key RBD symptoms and EEG slowing in REM sleep were alleviated.These results are consistent with a progressive degeneration in REM sleep promoting pathways.Our findings provide a foundation for further studies into RBD and its relationship to neurodegenerative diseases.
文摘Background:New research suggests that the composition(mix)of movement behaviors within a 24-h period may have important implications for health across the lifespan.Consistent with this integrated movement behavior paradigm,a number of countries across the world have developed and released 24-h movement guidelines for specific age groups.The purpose of this systematic review was to examine the associations between the 24-h time-use composition of movement behaviors,or adherence to 24-h movement guidelines,and multiple health indicators across the lifespan.Methods:Five online databases(PsycINFO,PubMed,SPORTDiscus,Web of Science,and Ovid MEDLINE)were searched for relevant peer-reviewed studies published between January 2015 and January 2020 that met the a priori inclusion criteria,with no study design limits.The methodological quality of research evidence for each individual study and for each health indicator was assessed by using a modified version of the Downs and Black checklist.Results:A total of 51 studies from 20 different countries met the inclusion criteria.A total of 31 studies examined adherence(meeting vs.not meeting)to 24-h movement guidelines,and 20 studies used compositional analyses to explore the 24-h time-use composition of movement behaviors.Findings indicated that meeting the 24-h movement guidelines were(1)not associated with adiposity among toddlers,(2)favorably associated with health-related quality of life,social-cognitive development,and behavioral and emotional problems among preschoolers,(3)favorably associated with global cognition,health-related quality of life,and healthy dietary patterns in children,and(4)favorably associated with adiposity,fitness,and cardiometabolic,mental,social,and emotional health among children and youth.Significant associations were also found between the composition of 24-h movement behaviors and indicators of(1)adiposity and bone and skeletal health among preschoolers,(2)health-related quality of life among children,(3)adiposity,fitness,and cardiometabolic,social,and emotional health among children and youth,(4)cardiometabolic health in adults,(5)adiposity and fitness among adults and older adults,and(6)mental health and risk of mortality among older adults.The quality of the available evidence ranged from poor to good.Conclusion:The current evidence indicates that the composition of movement behaviors within a 24-h period may have important implications for health at all ages and that meeting the current 24-h movement guidelines is associated with a number of desirable health indicators in children and youth.Future studies should employ longitudinal and experimental designs,include valid and reliable measures of 24-h movement behaviors,and examine a wide array of health indicators across all age groups.Such studies would confirm the results from the primarily cross-sectional evidence drawn from studies included in our review and further advance our understanding of the relationships between 24-h movement behaviors and health.
基金the financial support of the Ministry of Economy and Infrastructures and European Communitysupported by the Ministry of Economy and Infrastructures of Extremadura (PD 18015)funded by FEDER,FSE and Govern of Extremadura,grant numbers GR18102 and TA18027.
文摘Background:Meeting the 24-Hour Movement Guidelines(physical activity,screen time,and sleep duration) has been associated with positive health indicators.However,there are no previous meta-analyses that have examined the overall adherence to the 24-Hour Movement Guidelines from pre-school to adolescence across the world.Therefore,the main purpose of this systematic review and meta-analysis was to examine the overall(non)adherence to the 24-Hour Movement Guidelines among preschoolers,children,and adolescents worldwide.Methods:Four electronic databases(MEDLINE,Scopus,Web of Science,and Cochrane Database of Systematic Reviews) were searched for quantitative studies published in Spanish and English between January 2016 and May 2021.Studies that were conducted with apparently healthy participants and reported the overall(non)adherence to the 24-Hour Movement Guidelines in preschoolers and/or children and/or adolescents were included.Results:Sixty-three studies comprising 387,437 individuals(51% girls) aged 3-18 years from 23 countries were included.Overall,7.12%(95%confidence interval(95%CI):6.45%-7.78%) of youth met all three 24-Hour Movement Guidelines,and 19.21%(95%CI:16.73%-21.69%)met none of the 3 recommendations.Concerning sex,adherence to all recommendations was significantly lower in girls(3.75%,95%CI:3.23%-4.27%) than in boys(6.89%,95%CI:5.89%-7.89%)(p <0.001).However,there were no sex differences regarding adherence to any of the 3 individual recommendations(girls,15.66%,95%CI:8.40%-22.92%;boys,12.95%,95%CI:6.57%-19.33%).In terms of age group,adherence to the 3 recommendations was 11.26%(95%CI:8.68%-13.84%),10.31%(95%CI:7.49%-13.12%),and 2.68%(95%CI:1.78%-3.58%) in preschoolers,children,and adolescents,respectively.Conversely,8.81%(95%CI:5.97%-11.64%) of preschoolers,15.57%(95%CI:11.60%-19.54%) of children,and 28.59%(95%CI:22.42%-34.75%) of adolescents did not meet any of the recommendations.South America was the region with the lowest adherence(all:2.93%;none:31.72%).Overall adherence to the 24-Hour Movement Guidelines was positively related to country Human Development Index(β=-0.37,95%CI:-0.65 to-0.09;p=0.010).Conclusion:Most young people fail to meet the three 24-Hour Movement Guidelines,particularly adolescents,girls,and those who are from countries with a lower Human Development Index.Moreover,1 in 5 young people did not meet any of these recommendations.Therefore,these results highlight the need to develop age-and sex-specific strategies to promote these movement behaviors from the early stages of life.
基金the Research on Youth Physical Behavior and Mental Health Problems-Department of Science and Technology of Guangdong Province(2022SB0022).
文摘Background:Emerging adulthood is a pivotal life stage,presenting significant psychological and social changes,such as decreased sociability,depression,and other mental health problems.Previous studies have associated these changes with an unhealthy lifestyle.The 24-h movement guidelines for healthy lifestyles have been developed to promote appropriate health behaviors and improve individual wellness.However,the relationship between adherence to the 24-h movement guidelines and different characteristics of Chinese emerging adults is yet to be explored.This cross-sectional study aimed to investigate the association between adherence to the 24-h movement guidelines and four characteristics(self-exploration,instability,possibilities,and responsibility)of Chinese emerging adults.Methods:Overall,1,510 Chinese emerging adults aged 18–29 years were included in this study.Each participant completed a self-administered questionnaire that included questions on adherence to the 24-h movement guidelines(physical activity,sedentary behavior,and sleep)and the inventory of dimensions of emerging adulthood.Multivariable logistic regression analysis was employed to investigate the associations between adherence to the 24-h movement guidelines and each of the four characteristics.Results:The proportion of participants who adhered to the 24-h movement guidelines was 31.72%.Multiple regression analysis revealed a significantly negative relationship between adhering to more guidelines and instability(β=−0.51,p<0.001).A statistically significant association was observed between instability and meeting only sedentary behavior(β=−1.27,95%confidence interval[CI]:[−2.32,−0.24],p=0.02),sedentary behavior+sleep(β=−1.30,95%CI:[−2.24,−0.35],p<0.01),and physical activity+sedentary behavior(β=−1.08,95%CI:[1.94,−0.21],p=0.02)guidelines.Further,positive and significant associations were observed between possibilities and meeting the guidelines for only physical activity(β=0.70,95%CI:[0.14,1.27),p=0.01),only sleep(β=0.61,95%CI:[0.01,1.21],p=0.04),physical activity+sedentary behavior(β=0.56,95%CI:[0.04,1.07),p=0.01),and physical activity+sleep(β=0.76,95%CI:[0.23,1.27],p=0.01).Conclusions:These findings suggest that adherence to the 24-h movement guidelines was associated with instability in Chinese emerging adults.Future studies are warranted to verify our findings to highlight the importance of maintaining a heath lifestyle to promote health in emerging adulthood.
基金supported by the General Program in Education of Planning Project by Shanghai Philosophy and Social Science(A1904)the General Project of the National Social Science Foundation of China(19BTY077).
文摘Insufficient physical activity(PA),prolonged sedentary behavior(SB)and inadequate sleep(SLP)are detrimental factors to population health.To address health issues caused by insufficient PA,excessive SB and poor SLP,the World Health Organization(WHO)updated PA and SB guidelines for all populations aged from 5 years to 65 years and older in 2020.For children under 5 years old,the WHO issued the first global guidelines for PA,SB and SLP(collectively refer to movement behaviors)in April 2019.The guidelines applied a holistic approach to promote health behaviors,filling the gap of no comprehensive global movement guidelines for young children.Although the guidelines for young children offer guidance for health promotion,some research and practice implications and other issues should be mentioned.This commentary includes considerations for the importance of the WHO guidelines for younger children,critical analysis of evidence for developing the guidelines,and recommendations for future research and practice.The aim of this paper is to further advance health research in younger populations.
