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Programmable deaminative functionalization driven by N-nitroamines
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作者 Gen-Qiang Chen Xumu Zhang 《Science China Chemistry》 2026年第4期1569-1571,共3页
Aromatic amines represent one of the most prevalent functional groups in bioactive molecules,serving as cornerstones in natural products and pharmaceutical scaffolds[1].However,alternative strategies that utilize thes... Aromatic amines represent one of the most prevalent functional groups in bioactive molecules,serving as cornerstones in natural products and pharmaceutical scaffolds[1].However,alternative strategies that utilize these compounds have remained largely underexplored.For decades,strategies like the Sandmeyer reaction,despite being a foundational method for amine derivatization,have suffered from stoichiometric copper consumption. 展开更多
关键词 natural products n nitroamines bioactive moleculesserving sandmeyer reactiondespite bioactive molecules programmable deaminative functionalization pharmaceutical scaffolds howeveralternative aromatic amines
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