Cellular reprograming offers an opportunity to convert one somatic cell type into another,providing promising potential for disease modeling and regenerative medicine.This cell fate conversion can be achieved using li...Cellular reprograming offers an opportunity to convert one somatic cell type into another,providing promising potential for disease modeling and regenerative medicine.This cell fate conversion can be achieved using lineage-specific transcription factors,microRNAs or combinations of small molecules.A better understanding of how cell fate conversion is regulated will provide novel insights for precise manipulation of reprogramming,paving the way for developing novel strategies to regenerate the damaged tissue.展开更多
Cellular reprograming offers an opportunity to convert one somatic cell type into another,providing promising potential for disease modeling and regenerative medicine.This cell fate conversion can be achieved using li...Cellular reprograming offers an opportunity to convert one somatic cell type into another,providing promising potential for disease modeling and regenerative medicine.This cell fate conversion can be achieved using lineage-specific transcription factors,microRNAs or combinations of small molecules.A better understanding of how cell fate conversion is regulated will provide novel insights for precise manipulation of reprogramming,paving the way for developing novel strategies to regenerate the damaged tissue.展开更多
文摘Cellular reprograming offers an opportunity to convert one somatic cell type into another,providing promising potential for disease modeling and regenerative medicine.This cell fate conversion can be achieved using lineage-specific transcription factors,microRNAs or combinations of small molecules.A better understanding of how cell fate conversion is regulated will provide novel insights for precise manipulation of reprogramming,paving the way for developing novel strategies to regenerate the damaged tissue.
文摘Cellular reprograming offers an opportunity to convert one somatic cell type into another,providing promising potential for disease modeling and regenerative medicine.This cell fate conversion can be achieved using lineage-specific transcription factors,microRNAs or combinations of small molecules.A better understanding of how cell fate conversion is regulated will provide novel insights for precise manipulation of reprogramming,paving the way for developing novel strategies to regenerate the damaged tissue.