To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the stre...To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the strength and elastic modulus of mortar and concrete prepared with mechanism aggregates of the corresponding lithology,and the stress-strain curves of concrete were investigated.In this paper,a coarse aggregate and mortar matrix bonding assumption is proposed,and a prediction model for the elastic modulus of mortar is established by considering the lithology of the mechanism sand and the slurry components.An equivalent coarse aggregate elastic modulus model was established by considering factors such as coarse aggregate particle size,volume fraction,and mortar thickness between coarse aggregates.Based on the elastic modulus of the equivalent coarse aggregate and the remaining mortar,a prediction model for the elastic modulus of the two and three components of concrete in series and then in parallel was established,and the predicted values differed from the measured values within 10%.It is proposed that the coarse aggregate elastic modulus in highstrength concrete is the most critical factor affecting the elastic modulus of concrete,and as the coarse aggregate elastic modulus increases by 27.7%,the concrete elastic modulus increases by 19.5%.展开更多
Alkali-free SiO_(2)-Al_(2)O_(3)-CaO-MgO with different SiO_(2)/Al_(2)O_(3)mass ratios was prepared by conventional melt quenching method.The glass network structure,thermodynamic properties and elastic modulus changes...Alkali-free SiO_(2)-Al_(2)O_(3)-CaO-MgO with different SiO_(2)/Al_(2)O_(3)mass ratios was prepared by conventional melt quenching method.The glass network structure,thermodynamic properties and elastic modulus changes with SiO_(2)and Al_(2)O_(3)ratios were investigated using various techniques.It is found that when SiO_(2)is replaced by Al_(2)O_(3),the Q^(4) to Q^(3) transition of silicon-oxygen network decreases while the aluminum-oxygen network increases,which result in the transformation of Si-O-Si bonds to Si-O-Al bonds and an increase in glass network connectivity even though the intermolecular bond strength decreases.The glass transition temperature(T_(g))increases continuously,while the thermal expansion coefficient increases and high-temperature viscosity first decreases and then increases.Meanwhile,the elastic modulus values increase from 93 to 102 GPa.This indicates that the elastic modulus is mainly affected by packing factor and dissociation energy,and elements with higher packing factors and dissociation energies supplant those with lower values,resulting in increased rigidity within the glass.展开更多
s:A divide- by- 12 8/ 12 9or6 4/ 6 5 dual- modulus prescaler based on new optimized structure and dynam ic circuit technique im plem ented in 0 .2 5 μm CMOS digital technology is described.New optimized structure re...s:A divide- by- 12 8/ 12 9or6 4/ 6 5 dual- modulus prescaler based on new optimized structure and dynam ic circuit technique im plem ented in 0 .2 5 μm CMOS digital technology is described.New optimized structure reduces the propagation delay and has higher operating speed.Based on this structure,an im proved D- flip- flop(DFF) using dynam ic circuit technique is proposed.A prototype is fabricated and the measured results show that this prescaler works well in gigahertz frequency range and consumes only35 m W(including three power- hungry output buffers) when the input frequency is2 .5 GHz and the power supply voltage is2 .5 V.Due to its excellent perform ance,the prescaler could be applied to many RF system s.展开更多
杂种优势利用是提高大豆产量的有效策略之一,细胞质雄性不育(Cytoplasmic-nuclear Male Sterility,CMS)在大豆杂种优势利用中具有重要作用,为了阐明大豆CMS发生的分子机制,利用大豆CMS系W931A及其保持系W931B的单核小孢子(Uninucleate M...杂种优势利用是提高大豆产量的有效策略之一,细胞质雄性不育(Cytoplasmic-nuclear Male Sterility,CMS)在大豆杂种优势利用中具有重要作用,为了阐明大豆CMS发生的分子机制,利用大豆CMS系W931A及其保持系W931B的单核小孢子(Uninucleate Microspore,UM)和二胞花粉期(Binucleate Pollen,BP)花蕾进行代谢组学研究,并与转录组数据联合分析,挖掘大豆CMS相关基因及代谢途径。代谢组分析结果显示,在CMS系W931A的UM和BP阶段分别鉴定到147和305个差异代谢物,主要包括脂质及类脂分子化合物、苯丙烷及聚酮化合物和有机杂环化合物等。转录组和代谢组联合分析揭示,差异表达基因(Differentially Expressed Genes,DEGs)和差异代谢物主要参与黄酮类化合物生物合成、苯丙氨酸代谢和苯丙烷类生物合成。在花粉发育过程中,黄酮类及衍生物的合成被显著抑制,F3H(Glyma.01G166200)和FLS(Glyma.06G110600)基因在CMS系W931A中显著下调表达,推测其在相应代谢途径中发挥关键调控作用,导致花药中相关代谢物的差异,进而引发不育系花粉的败育。研究结果有助于构建大豆CMS分子调控网络,并推动大豆CMS分子机制的研究进程。展开更多
Micro-mechanical properties of a claystone were tested after undergoing alkaline perturbation on site(Tournemire,CD borehole)for 18 years.In a saturated context and outside the excavation disturbed zone(EDZ),the clays...Micro-mechanical properties of a claystone were tested after undergoing alkaline perturbation on site(Tournemire,CD borehole)for 18 years.In a saturated context and outside the excavation disturbed zone(EDZ),the claystone exhibits a 11.6-mm black rim at the cement/paste interface,which shows a different mechanical behaviour from the rest of the claystone.Three sets of measurements of elastic modulus were performed using:(i)nano-indentation tests with a constant indentation depth of 2 mm,(ii)microindentation tests with a constant indentation depth of 20 mm,and(iii)meso-compression tests with a constant displacement of 200 mm.The increase of the modulus of deformability in the black rim is between 15 GPa and 20 GPa according to the scale.Moreover,an overall decrease of the modulus of deformability from the smallest to the largest scale is observed in each zone.In view of the mineralogy and petrographic observations,higher values of modulus of deformability in the black rim are related to carbonate content and its distribution.Precipitation of cementitious carbonates as inclusions and very thin partings leads to hardening of the claystone.展开更多
Young's modulus and Poisson's ratio are crucial parameters for reservoir characterization and rock brittleness evaluation.Conventional methods often rely on indirect computation or approximations of the Zoeppr...Young's modulus and Poisson's ratio are crucial parameters for reservoir characterization and rock brittleness evaluation.Conventional methods often rely on indirect computation or approximations of the Zoeppritz equations to estimate Young's modulus,which can introduce cumulative errors and reduce the accuracy of inversion results.To address these issues,this paper introduces the analytical solution of the Zoeppritz equation into the inversion process.The equation is re-derived and expressed in terms of Young's modulus,Poisson's ratio,and density.Within the Bayesian framework,we construct an objective function for the joint inversion of PP and PS waves.Traditional gradient-based algorithms often suffer from low precision and the computational complexity.In this study,we address limitations of conventional approaches related to low precision and complicated code by using Circle chaotic mapping,Levy flights,and Gaussian mutation to optimize the quantum particle swarm optimization(QPSO),named improved quantum particle swarm optimization(IQPSO).The IQPSO demonstrates superior global optimization capabilities.We test the proposed inversion method with both synthetic and field data.The test results demonstrate the proposed method's feasibility and effectiveness,indicating an improvement in inversion accuracy over traditional methods.展开更多
Optogenetic has been widely applied in various pathogenesis investigations of neuropathic diseases since its accurate and targeted regulation of neuronal activity.However,due to the mismatch between the soft tissues a...Optogenetic has been widely applied in various pathogenesis investigations of neuropathic diseases since its accurate and targeted regulation of neuronal activity.However,due to the mismatch between the soft tissues and the optical waveguide,the long-term neural regulation within soft tissue(such as brain and spinal cord)by implantable optical fibers is a large challenge.Herein,we designed a modulus selfadaptive hydrogel optical fiber(MSHOF)with tunable mechanical properties(Young’modulus was tunable in the range of 0.32-10.56MPa)and low light attenuation(0.12-0.21 dB/cm,472nm laser light),which adapts to light transmission under soft tissues.These advantages of MSHOF can ensure the effectiveness of optogenetic stimulation meanwhile safeguarding the safety of the brain/materials interaction interface.In addition,this work provides more design possibilities of MSHOF for photogenetic stimuli and has significant application prospects in photomedical therapy.展开更多
Porous designs effectively reduce stress shielding in metallic orthopedic implants.However,current porous structures often fail to adequately meet the needs of patients with osteoporosis and low-modulus body regions.T...Porous designs effectively reduce stress shielding in metallic orthopedic implants.However,current porous structures often fail to adequately meet the needs of patients with osteoporosis and low-modulus body regions.This study proposes a sinusoidal-based lattice structure for an ultralow and widely tunable modulus design,aiming to match diverse bone tissue requirements and enhance biomechanical compatibility.Parametric modeling and finite element analysis were used to evaluate the performance of this structure.Results show that,within the design range suitable for bone growth,the elastic modulus of this lattice structure is tunable over a wide range,from 0.09 to 32.67 GPa,outperforming existing porous structures.The lowest value closely matched the minimum mechanical properties of human cancellous bone among porous structures.Moreover,the structure exhibited distinct anisotropic characteristics,allowing for directional design based on mechanical requirements.The structure’s permeability ranged from 1.19×10^(-8) m^(2) to 2.3×10^(-7) m^(2),making it highly compatible with human cancellous bone and meeting the requirements of orthopedic implants.Samples with porosities ranging from 46% to 87% were successfully fabricated using powder bed fusion additive manufacturing,validating the simulation predictions.This tunable low-modulus lattice structure provides a novel approach for developing personalized orthopedic implants,particularly for patients with specialized needs such as osteoporosis,and can potentially enhance biomechanical compatibility and long-term stability.展开更多
Discrete fracture network(DFN)commonly existing in natural rock masses plays an important role in geological complexity which can influence rock fracturing behaviour during fluid injection.This paper simulated the hyd...Discrete fracture network(DFN)commonly existing in natural rock masses plays an important role in geological complexity which can influence rock fracturing behaviour during fluid injection.This paper simulated the hydraulic fracturing process in lab-scale coal samples with DFNs and the induced seismic activities by the discrete element method(DEM).The effects of DFNs on hydraulic fracturing,induced seismicity and elastic property changes have been concluded.Denser DFNs can comprehensively decrease the peak injection pressure and injection duration.The proportion of strong seismic events increases first and then decreases with increasing DFN density.In addition,the relative modulus of the rock mass is derived innovatively from breakdown pressure,breakdown fracture length and the related initiation time.Increasing DFN densities among large(35–60 degrees)and small(0–30 degrees)fracture dip angles show opposite evolution trends in relative modulus.The transitional point(dip angle)for the opposite trends is also proportionally affected by the friction angle of the rock mass.The modelling results have much practical meaning to infer the density and geometry of pre-existing fractures and the elastic property of rock mass in the field,simply based on the hydraulic fracturing and induced seismicity monitoring data.展开更多
基金Funded by State Railway Administration Research Project(No.2023JS007)National Natural Science Foundation of China(No.52438002)+1 种基金Research and Development Programs for Science and Technology of China Railways Corporation(No.J2023G003)New Cornerstone Science Foundation through the XPLORER PRIZE。
文摘To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the strength and elastic modulus of mortar and concrete prepared with mechanism aggregates of the corresponding lithology,and the stress-strain curves of concrete were investigated.In this paper,a coarse aggregate and mortar matrix bonding assumption is proposed,and a prediction model for the elastic modulus of mortar is established by considering the lithology of the mechanism sand and the slurry components.An equivalent coarse aggregate elastic modulus model was established by considering factors such as coarse aggregate particle size,volume fraction,and mortar thickness between coarse aggregates.Based on the elastic modulus of the equivalent coarse aggregate and the remaining mortar,a prediction model for the elastic modulus of the two and three components of concrete in series and then in parallel was established,and the predicted values differed from the measured values within 10%.It is proposed that the coarse aggregate elastic modulus in highstrength concrete is the most critical factor affecting the elastic modulus of concrete,and as the coarse aggregate elastic modulus increases by 27.7%,the concrete elastic modulus increases by 19.5%.
基金Supported by the National Key Research Program(No.2024-1129-954-112)National Natural Science Foundation of China(No.52372033)Guangxi Science and Technology Major Program(No.AA24263054)。
文摘Alkali-free SiO_(2)-Al_(2)O_(3)-CaO-MgO with different SiO_(2)/Al_(2)O_(3)mass ratios was prepared by conventional melt quenching method.The glass network structure,thermodynamic properties and elastic modulus changes with SiO_(2)and Al_(2)O_(3)ratios were investigated using various techniques.It is found that when SiO_(2)is replaced by Al_(2)O_(3),the Q^(4) to Q^(3) transition of silicon-oxygen network decreases while the aluminum-oxygen network increases,which result in the transformation of Si-O-Si bonds to Si-O-Al bonds and an increase in glass network connectivity even though the intermolecular bond strength decreases.The glass transition temperature(T_(g))increases continuously,while the thermal expansion coefficient increases and high-temperature viscosity first decreases and then increases.Meanwhile,the elastic modulus values increase from 93 to 102 GPa.This indicates that the elastic modulus is mainly affected by packing factor and dissociation energy,and elements with higher packing factors and dissociation energies supplant those with lower values,resulting in increased rigidity within the glass.
文摘s:A divide- by- 12 8/ 12 9or6 4/ 6 5 dual- modulus prescaler based on new optimized structure and dynam ic circuit technique im plem ented in 0 .2 5 μm CMOS digital technology is described.New optimized structure reduces the propagation delay and has higher operating speed.Based on this structure,an im proved D- flip- flop(DFF) using dynam ic circuit technique is proposed.A prototype is fabricated and the measured results show that this prescaler works well in gigahertz frequency range and consumes only35 m W(including three power- hungry output buffers) when the input frequency is2 .5 GHz and the power supply voltage is2 .5 V.Due to its excellent perform ance,the prescaler could be applied to many RF system s.
文摘Micro-mechanical properties of a claystone were tested after undergoing alkaline perturbation on site(Tournemire,CD borehole)for 18 years.In a saturated context and outside the excavation disturbed zone(EDZ),the claystone exhibits a 11.6-mm black rim at the cement/paste interface,which shows a different mechanical behaviour from the rest of the claystone.Three sets of measurements of elastic modulus were performed using:(i)nano-indentation tests with a constant indentation depth of 2 mm,(ii)microindentation tests with a constant indentation depth of 20 mm,and(iii)meso-compression tests with a constant displacement of 200 mm.The increase of the modulus of deformability in the black rim is between 15 GPa and 20 GPa according to the scale.Moreover,an overall decrease of the modulus of deformability from the smallest to the largest scale is observed in each zone.In view of the mineralogy and petrographic observations,higher values of modulus of deformability in the black rim are related to carbonate content and its distribution.Precipitation of cementitious carbonates as inclusions and very thin partings leads to hardening of the claystone.
基金supported by Fundamental Research Funds for the Central Universities,CHD300102264715National Key Research and Development Program of China under Grant 2021YFA0716902Natural Science Basic Research Program of Shaanxi 2024JCYBMS-199。
文摘Young's modulus and Poisson's ratio are crucial parameters for reservoir characterization and rock brittleness evaluation.Conventional methods often rely on indirect computation or approximations of the Zoeppritz equations to estimate Young's modulus,which can introduce cumulative errors and reduce the accuracy of inversion results.To address these issues,this paper introduces the analytical solution of the Zoeppritz equation into the inversion process.The equation is re-derived and expressed in terms of Young's modulus,Poisson's ratio,and density.Within the Bayesian framework,we construct an objective function for the joint inversion of PP and PS waves.Traditional gradient-based algorithms often suffer from low precision and the computational complexity.In this study,we address limitations of conventional approaches related to low precision and complicated code by using Circle chaotic mapping,Levy flights,and Gaussian mutation to optimize the quantum particle swarm optimization(QPSO),named improved quantum particle swarm optimization(IQPSO).The IQPSO demonstrates superior global optimization capabilities.We test the proposed inversion method with both synthetic and field data.The test results demonstrate the proposed method's feasibility and effectiveness,indicating an improvement in inversion accuracy over traditional methods.
基金supported by the National Key Research and Development Program of China(Nos.2021YFA1201302 and 2021YFA1201300)the National Natural Science Foundation of China(Nos.52303033,52173029)+1 种基金Shanghai Sailing Program(No.23YF1400400)the Natural Science Foundation of Shanghai(No.21ZR1400500).
文摘Optogenetic has been widely applied in various pathogenesis investigations of neuropathic diseases since its accurate and targeted regulation of neuronal activity.However,due to the mismatch between the soft tissues and the optical waveguide,the long-term neural regulation within soft tissue(such as brain and spinal cord)by implantable optical fibers is a large challenge.Herein,we designed a modulus selfadaptive hydrogel optical fiber(MSHOF)with tunable mechanical properties(Young’modulus was tunable in the range of 0.32-10.56MPa)and low light attenuation(0.12-0.21 dB/cm,472nm laser light),which adapts to light transmission under soft tissues.These advantages of MSHOF can ensure the effectiveness of optogenetic stimulation meanwhile safeguarding the safety of the brain/materials interaction interface.In addition,this work provides more design possibilities of MSHOF for photogenetic stimuli and has significant application prospects in photomedical therapy.
基金supported by National Key R&D Program of China(Grant No.2022YFB4600500)Fundamental Research Funds for the Central Universities,and the Program for Innovation Team of Shaanxi Province(Grant No.2023-CX-TD-17).
文摘Porous designs effectively reduce stress shielding in metallic orthopedic implants.However,current porous structures often fail to adequately meet the needs of patients with osteoporosis and low-modulus body regions.This study proposes a sinusoidal-based lattice structure for an ultralow and widely tunable modulus design,aiming to match diverse bone tissue requirements and enhance biomechanical compatibility.Parametric modeling and finite element analysis were used to evaluate the performance of this structure.Results show that,within the design range suitable for bone growth,the elastic modulus of this lattice structure is tunable over a wide range,from 0.09 to 32.67 GPa,outperforming existing porous structures.The lowest value closely matched the minimum mechanical properties of human cancellous bone among porous structures.Moreover,the structure exhibited distinct anisotropic characteristics,allowing for directional design based on mechanical requirements.The structure’s permeability ranged from 1.19×10^(-8) m^(2) to 2.3×10^(-7) m^(2),making it highly compatible with human cancellous bone and meeting the requirements of orthopedic implants.Samples with porosities ranging from 46% to 87% were successfully fabricated using powder bed fusion additive manufacturing,validating the simulation predictions.This tunable low-modulus lattice structure provides a novel approach for developing personalized orthopedic implants,particularly for patients with specialized needs such as osteoporosis,and can potentially enhance biomechanical compatibility and long-term stability.
基金Australian Research Council Linkage Program(LP200301404)for sponsoring this researchthe financial support provided by the State Key Laboratory of Geohazard Prevention and Geoenvironment Protection(Chengdu University of Technology,SKLGP2021K002)National Natural Science Foundation of China(52374101,32111530138).
文摘Discrete fracture network(DFN)commonly existing in natural rock masses plays an important role in geological complexity which can influence rock fracturing behaviour during fluid injection.This paper simulated the hydraulic fracturing process in lab-scale coal samples with DFNs and the induced seismic activities by the discrete element method(DEM).The effects of DFNs on hydraulic fracturing,induced seismicity and elastic property changes have been concluded.Denser DFNs can comprehensively decrease the peak injection pressure and injection duration.The proportion of strong seismic events increases first and then decreases with increasing DFN density.In addition,the relative modulus of the rock mass is derived innovatively from breakdown pressure,breakdown fracture length and the related initiation time.Increasing DFN densities among large(35–60 degrees)and small(0–30 degrees)fracture dip angles show opposite evolution trends in relative modulus.The transitional point(dip angle)for the opposite trends is also proportionally affected by the friction angle of the rock mass.The modelling results have much practical meaning to infer the density and geometry of pre-existing fractures and the elastic property of rock mass in the field,simply based on the hydraulic fracturing and induced seismicity monitoring data.
