Modularized circuit designs for chaotic systems are introduced in this paper.Especially,a typical improved modularized design strategy is proposed and applied to a new hyper-chaotic system circuit implementation.In th...Modularized circuit designs for chaotic systems are introduced in this paper.Especially,a typical improved modularized design strategy is proposed and applied to a new hyper-chaotic system circuit implementation.In this paper,the detailed design procedures are described.Multisim simulations and physical experiments are conducted,and the simulation results are compared with Matlab simulation results for different system parameter pairs.These results are consistent with each other and they verify the existence of the hyper-chaotic attractor for this new hyper-chaotic system.展开更多
合成生物学作为基于工程化理念的生命系统工程设计学科,其核心挑战在于基于工程化原理,“由下至上”建立由基因元件组装而成的各种生物功能模块和系统,并建立序列-功能映射的预测模型。大语言模型(large language models, LLMs)凭借其...合成生物学作为基于工程化理念的生命系统工程设计学科,其核心挑战在于基于工程化原理,“由下至上”建立由基因元件组装而成的各种生物功能模块和系统,并建立序列-功能映射的预测模型。大语言模型(large language models, LLMs)凭借其自监督预训练机制与注意力架构优势,通过解析DNA/RNA序列中的语法规则与语义特征,在从基因元件到基因组系统的多个微观层次,为生物序列的跨尺度建模提供了新工具。本综述聚焦LLMs如何辅助解决合成生物学中的关键设计难题,系统地综述了LLMs在合成生物学中的创新应用,系统梳理了其在基因元件、基因线路、基因簇重构、基因组等多个层次的研究进展,并探讨其如何与传统模型及工程化方法结合,共同提升面向模块化生命系统构建的理性设计能力,并分析当前面临的挑战与未来发展方向。展开更多
基金supported by the Young Scientists Fund of the National Natural Science Foundation of China(Grant No.61403395)the Natural Science Foundation of Tianjin,China(Grant No.13JCYBJC39000)+3 种基金the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry of Chinathe Fund from the Tianjin Key Laboratory of Civil Aircraft Airworthiness and Maintenance in Civil Aviation of China(Grant No.104003020106)the National Basic Research Program of China(Grant No.2014CB744904)the Fund for the Scholars of Civil Aviation University of China(Grant No.2012QD21x)
文摘Modularized circuit designs for chaotic systems are introduced in this paper.Especially,a typical improved modularized design strategy is proposed and applied to a new hyper-chaotic system circuit implementation.In this paper,the detailed design procedures are described.Multisim simulations and physical experiments are conducted,and the simulation results are compared with Matlab simulation results for different system parameter pairs.These results are consistent with each other and they verify the existence of the hyper-chaotic attractor for this new hyper-chaotic system.
文摘合成生物学作为基于工程化理念的生命系统工程设计学科,其核心挑战在于基于工程化原理,“由下至上”建立由基因元件组装而成的各种生物功能模块和系统,并建立序列-功能映射的预测模型。大语言模型(large language models, LLMs)凭借其自监督预训练机制与注意力架构优势,通过解析DNA/RNA序列中的语法规则与语义特征,在从基因元件到基因组系统的多个微观层次,为生物序列的跨尺度建模提供了新工具。本综述聚焦LLMs如何辅助解决合成生物学中的关键设计难题,系统地综述了LLMs在合成生物学中的创新应用,系统梳理了其在基因元件、基因线路、基因簇重构、基因组等多个层次的研究进展,并探讨其如何与传统模型及工程化方法结合,共同提升面向模块化生命系统构建的理性设计能力,并分析当前面临的挑战与未来发展方向。