In order to provide a judicious pulse waveform design required for ultra-wideband(UWB)communication to enable the UWB spectral mask compatible and coexistent with other existing wireless communication systems,a semi-d...In order to provide a judicious pulse waveform design required for ultra-wideband(UWB)communication to enable the UWB spectral mask compatible and coexistent with other existing wireless communication systems,a semi-definite programming(SDP)based pulse waveform design method for UWB radios is introduced and a further analysis is given in this paper.By using Sedumi and Yalmip toolboxes of Matlab,the procedure of solving the SDP problem is simplified.Simulation results show that this SDP based pulse waveform design method can be used to design pulses that fulfill the Federal Communications Commission(FCC)spectral mask strictly and optimize the power efficiency at the same time.This paper also analyzes the influences of the power efficiency duing to the changes of sampling interval and the number of combined pulses,and then the optimal sampling interval that maximizes the transmission power can be found.展开更多
Modified clay(MC),an effective material used for the emergency elimination of algal blooms,can rapidly reduce the biomass of harmful algal blooms(HABs)via flocculation.After that,MC can still control bloom population ...Modified clay(MC),an effective material used for the emergency elimination of algal blooms,can rapidly reduce the biomass of harmful algal blooms(HABs)via flocculation.After that,MC can still control bloom population through indirect effects such as oxidative stress,whichwas initially proposed to be related to programmedcell death(PCD)at molecular level.To further study theMC induced cell death in residual bloom organisms,especially identifying PCD process,we studied the physiological state of the residual Prorocentrum donghaiense.The experimental results showed that flocculation changed the physiological state of the residual cells,as evidenced by growth inhibition and increased reactive oxygen species production.Moreover,this research provides biochemical and ultrastructural evidence showing that MC induces PCD in P.donghaiense.Nuclear changes were observed,and increased caspase-like activity,externalization of phosphatidylserine and DNA fragmentation were detected in MC-treated groups and quantified.And the mitochondrial apoptosis pathway was activated in both MC-treated groups.Besides,the features of MC-induced PCD in a unicellular organism were summarized and its concentration dependent manner was proved.All our preliminary results elucidate the mechanism through which MC can further control HABs by inducing PCD and suggest a promising application of PCD in bloom control.展开更多
This paper proposes an inner product Laplacian embedding algorithm based on semi-definite programming, named as IPLE algorithm. The new algorithm learns a geodesic distance-based kernel matrix by using semi-definite p...This paper proposes an inner product Laplacian embedding algorithm based on semi-definite programming, named as IPLE algorithm. The new algorithm learns a geodesic distance-based kernel matrix by using semi-definite programming under the constraints of local contraction. The criterion function is to make the neighborhood points on manifold as close as possible while the geodesic distances between those distant points are preserved. The IPLE algorithm sufficiently integrates the advantages of LE, ISOMAP and MVU algorithms. The comparison experiments on two image datasets from COIL-20 images and USPS handwritten digit images are performed by applying LE, ISOMAP, MVU and the proposed IPLE. Experimental results show that the intrinsic low-dimensional coordinates obtained by our algorithm preserve more information according to the fraction of the dominant eigenvalues and can obtain the better comprehensive performance in clustering and manifold structure.展开更多
In this paper, a modified version of the Classical Lagrange Multiplier method is developed for convex quadratic optimization problems. The method, which is evolved from the first order derivative test for optimality o...In this paper, a modified version of the Classical Lagrange Multiplier method is developed for convex quadratic optimization problems. The method, which is evolved from the first order derivative test for optimality of the Lagrangian function with respect to the primary variables of the problem, decomposes the solution process into two independent ones, in which the primary variables are solved for independently, and then the secondary variables, which are the Lagrange multipliers, are solved for, afterward. This is an innovation that leads to solving independently two simpler systems of equations involving the primary variables only, on one hand, and the secondary ones on the other. Solutions obtained for small sized problems (as preliminary test of the method) demonstrate that the new method is generally effective in producing the required solutions.展开更多
During spaceflight,the cardiovascular system undergoes remarkable adaptation to microgravity and faces the risk of cardiac remodeling.Therefore,the effects and mechanisms of microgravity on cardiac morphology,physiolo...During spaceflight,the cardiovascular system undergoes remarkable adaptation to microgravity and faces the risk of cardiac remodeling.Therefore,the effects and mechanisms of microgravity on cardiac morphology,physiology,metabolism,and cellular biology need to be further investigated.Since China started constructing the China Space Station(CSS)in 2021,we have taken advantage of the Shenzhou-13 capsule to send human pluripotent stem cell-derived cardiomyocytes(hPSC-CMs)to the Tianhe core module of the CSS.In this study,hPSC-CMs subjected to space microgravity showed decreased beating rate and abnormal intracellular calcium cycling.Metabolomic and transcriptomic analyses revealed a battery of metabolic remodeling of hPSC-CMs in spaceflight,especially thiamine metabolism.The microgravity condition blocked the thiamine intake in hPSC-CMs.The decline of thiamine utilization under microgravity or by its antagonistic analog amprolium affected the process of the tricarboxylic acid cycle.It decreased ATP production,which led to cytoskeletal remodeling and calcium homeostasis imbalance in hPSC-CMs.More importantly,in vitro and in vivo studies suggest that thiamine supplementation could reverse the adaptive changes induced by simulated microgravity.This study represents the first astrobiological study on the China Space Station and lays a solid foundation for further aerospace biomedical research.These data indicate that intervention of thiamine-modified metabolic reprogramming in human cardiomyocytes during spaceflight might be a feasible countermeasure against microgravity.展开更多
This paper proposes nonlinear Lagrangians based on modified Fischer-Burmeister NCP functions for solving nonlinear programming problems with inequality constraints. The convergence theorem shows that the sequence of p...This paper proposes nonlinear Lagrangians based on modified Fischer-Burmeister NCP functions for solving nonlinear programming problems with inequality constraints. The convergence theorem shows that the sequence of points generated by this nonlinear La- grange algorithm is locally convergent when the penalty parameter is less than a threshold under a set of suitable conditions on problem functions, and the error bound of solution, depending on the penalty parameter, is also established. It is shown that the condition number of the nonlinear Lagrangian Hessian at the optimal solution is proportional to the controlling penalty parameter. Moreover, the paper develops the dual algorithm associ- ated with the proposed nonlinear Lagrangians. Numerical results reported suggest that the dual algorithm based on proposed nonlinear Lagrangians is effective for solving some nonlinear optimization problems.展开更多
The effects of plasticizers,antioxidants and burning rate modifiers on the aging performance of the composite solid propellant based on hydroxyl-terminated polybutadiene(HTPB)/hexamethylene diisocyanate(HMDI)were expl...The effects of plasticizers,antioxidants and burning rate modifiers on the aging performance of the composite solid propellant based on hydroxyl-terminated polybutadiene(HTPB)/hexamethylene diisocyanate(HMDI)were explored by apply-ing an accelerated aging program for 90 day at 70 ℃. The HTPB propellant matrix with the diisooctyl sebacate(DOS)as plasti-cizers and diisooctyl azelate(DOZ), antioxidants as N,N ′-Diphenyl-p-phenylenediamine(AO) and 2,2′-methylenebis(4-methyl-6-tert-butylphenol)(cyanox 2246)and burning rate modifiers as barium ferrite(BF),copper chromites(CC)and fer-ric oxide(FO)were varied. Results show that sample(S1)which based on DOS decreases the stress value and increases the strain value which considered to be an excellent start for aging program. Sample(S3)containing AO presents the higher resis-tance to oxidation showing the better performance that reflects on increasing the shelf life of the composite solid propellant mo-tor. Sample(S5)which based on BF enhances the ballistic performance among over the other tested two samples. The accelerat-ed aging program allowed us to estimate the motor in-service lifetime.展开更多
In this paper we introduce a primal-dual potential reduction algorithm for positive semi-definite programming. Using the symetric preserving scalings for both primal and dual interior matrices, we can construct an alg...In this paper we introduce a primal-dual potential reduction algorithm for positive semi-definite programming. Using the symetric preserving scalings for both primal and dual interior matrices, we can construct an algorithm which is very similar to the primal-dual potential reduction algorithm of Huang and Kortanek [6] for linear programming. The complexity of the algorithm is either O(nlog(X0 · S0/ε) or O(nlog(X0· S0/ε) depends on the value of ρ in the primal-dual potential function, where X0 and S0 is the initial interior matrices of the positive semi-definite programming.展开更多
This paper first applies the fuzzy set theory to multi-objective semi-definite program-ming （MSDP）, and proposes the fuzzy multi-objective semi-definite programming （FMSDP） model whose optimal efficient solution i...This paper first applies the fuzzy set theory to multi-objective semi-definite program-ming （MSDP）, and proposes the fuzzy multi-objective semi-definite programming （FMSDP） model whose optimal efficient solution is defined for the first time, too. By constructing a membership function, the FMSDP is translated to the MSDP. Then we prove that the optimal efficient solution of FMSDP is consistent with the efficient solution of MSDP and present the optimality condition about these programming. At last, we give an algorithm for FMSDP by introducing a new membership function and a series of transformation.展开更多
基金the National Natural Science Foundation of China (Grant No.60432040)Program for New Century Excellent Talents in University(Grant No.NCET-04-0332)
文摘In order to provide a judicious pulse waveform design required for ultra-wideband(UWB)communication to enable the UWB spectral mask compatible and coexistent with other existing wireless communication systems,a semi-definite programming(SDP)based pulse waveform design method for UWB radios is introduced and a further analysis is given in this paper.By using Sedumi and Yalmip toolboxes of Matlab,the procedure of solving the SDP problem is simplified.Simulation results show that this SDP based pulse waveform design method can be used to design pulses that fulfill the Federal Communications Commission(FCC)spectral mask strictly and optimize the power efficiency at the same time.This paper also analyzes the influences of the power efficiency duing to the changes of sampling interval and the number of combined pulses,and then the optimal sampling interval that maximizes the transmission power can be found.
基金supported by the Taishan Scholars Climbing Program of Shandong Province of 2019,the Special Research Assistant Program of Chinese Academy of Sciences,China Postdoctoral Science Foundation Funded Project(No.2020M672153)the AoShan Talents Cultivation Program from Qingdao National Laboratory for Marine Science and Technology(No.2017ASTCP-OS16).
文摘Modified clay(MC),an effective material used for the emergency elimination of algal blooms,can rapidly reduce the biomass of harmful algal blooms(HABs)via flocculation.After that,MC can still control bloom population through indirect effects such as oxidative stress,whichwas initially proposed to be related to programmedcell death(PCD)at molecular level.To further study theMC induced cell death in residual bloom organisms,especially identifying PCD process,we studied the physiological state of the residual Prorocentrum donghaiense.The experimental results showed that flocculation changed the physiological state of the residual cells,as evidenced by growth inhibition and increased reactive oxygen species production.Moreover,this research provides biochemical and ultrastructural evidence showing that MC induces PCD in P.donghaiense.Nuclear changes were observed,and increased caspase-like activity,externalization of phosphatidylserine and DNA fragmentation were detected in MC-treated groups and quantified.And the mitochondrial apoptosis pathway was activated in both MC-treated groups.Besides,the features of MC-induced PCD in a unicellular organism were summarized and its concentration dependent manner was proved.All our preliminary results elucidate the mechanism through which MC can further control HABs by inducing PCD and suggest a promising application of PCD in bloom control.
文摘This paper proposes an inner product Laplacian embedding algorithm based on semi-definite programming, named as IPLE algorithm. The new algorithm learns a geodesic distance-based kernel matrix by using semi-definite programming under the constraints of local contraction. The criterion function is to make the neighborhood points on manifold as close as possible while the geodesic distances between those distant points are preserved. The IPLE algorithm sufficiently integrates the advantages of LE, ISOMAP and MVU algorithms. The comparison experiments on two image datasets from COIL-20 images and USPS handwritten digit images are performed by applying LE, ISOMAP, MVU and the proposed IPLE. Experimental results show that the intrinsic low-dimensional coordinates obtained by our algorithm preserve more information according to the fraction of the dominant eigenvalues and can obtain the better comprehensive performance in clustering and manifold structure.
文摘In this paper, a modified version of the Classical Lagrange Multiplier method is developed for convex quadratic optimization problems. The method, which is evolved from the first order derivative test for optimality of the Lagrangian function with respect to the primary variables of the problem, decomposes the solution process into two independent ones, in which the primary variables are solved for independently, and then the secondary variables, which are the Lagrange multipliers, are solved for, afterward. This is an innovation that leads to solving independently two simpler systems of equations involving the primary variables only, on one hand, and the secondary ones on the other. Solutions obtained for small sized problems (as preliminary test of the method) demonstrate that the new method is generally effective in producing the required solutions.
基金This study was supported by the National Key R&D Program of China(2022YFA1104300)the Space Medical Experiment Project of China Manned Space Program(HYZHXM01018)+4 种基金the National Natural Science Foundation of China(82241202)Scientific Innovation Project of the State Key Laboratory of Radiation Medicine and Protection(GZC00101)The Natural Science Foundation of the Jiangsu Higher Education Institutions of China(21KJB310003)Jiangsu Cardiovascular Medicine Innovation Center(CXZX202210)National Center for International Research(2017B01012).
文摘During spaceflight,the cardiovascular system undergoes remarkable adaptation to microgravity and faces the risk of cardiac remodeling.Therefore,the effects and mechanisms of microgravity on cardiac morphology,physiology,metabolism,and cellular biology need to be further investigated.Since China started constructing the China Space Station(CSS)in 2021,we have taken advantage of the Shenzhou-13 capsule to send human pluripotent stem cell-derived cardiomyocytes(hPSC-CMs)to the Tianhe core module of the CSS.In this study,hPSC-CMs subjected to space microgravity showed decreased beating rate and abnormal intracellular calcium cycling.Metabolomic and transcriptomic analyses revealed a battery of metabolic remodeling of hPSC-CMs in spaceflight,especially thiamine metabolism.The microgravity condition blocked the thiamine intake in hPSC-CMs.The decline of thiamine utilization under microgravity or by its antagonistic analog amprolium affected the process of the tricarboxylic acid cycle.It decreased ATP production,which led to cytoskeletal remodeling and calcium homeostasis imbalance in hPSC-CMs.More importantly,in vitro and in vivo studies suggest that thiamine supplementation could reverse the adaptive changes induced by simulated microgravity.This study represents the first astrobiological study on the China Space Station and lays a solid foundation for further aerospace biomedical research.These data indicate that intervention of thiamine-modified metabolic reprogramming in human cardiomyocytes during spaceflight might be a feasible countermeasure against microgravity.
文摘This paper proposes nonlinear Lagrangians based on modified Fischer-Burmeister NCP functions for solving nonlinear programming problems with inequality constraints. The convergence theorem shows that the sequence of points generated by this nonlinear La- grange algorithm is locally convergent when the penalty parameter is less than a threshold under a set of suitable conditions on problem functions, and the error bound of solution, depending on the penalty parameter, is also established. It is shown that the condition number of the nonlinear Lagrangian Hessian at the optimal solution is proportional to the controlling penalty parameter. Moreover, the paper develops the dual algorithm associ- ated with the proposed nonlinear Lagrangians. Numerical results reported suggest that the dual algorithm based on proposed nonlinear Lagrangians is effective for solving some nonlinear optimization problems.
文摘The effects of plasticizers,antioxidants and burning rate modifiers on the aging performance of the composite solid propellant based on hydroxyl-terminated polybutadiene(HTPB)/hexamethylene diisocyanate(HMDI)were explored by apply-ing an accelerated aging program for 90 day at 70 ℃. The HTPB propellant matrix with the diisooctyl sebacate(DOS)as plasti-cizers and diisooctyl azelate(DOZ), antioxidants as N,N ′-Diphenyl-p-phenylenediamine(AO) and 2,2′-methylenebis(4-methyl-6-tert-butylphenol)(cyanox 2246)and burning rate modifiers as barium ferrite(BF),copper chromites(CC)and fer-ric oxide(FO)were varied. Results show that sample(S1)which based on DOS decreases the stress value and increases the strain value which considered to be an excellent start for aging program. Sample(S3)containing AO presents the higher resis-tance to oxidation showing the better performance that reflects on increasing the shelf life of the composite solid propellant mo-tor. Sample(S5)which based on BF enhances the ballistic performance among over the other tested two samples. The accelerat-ed aging program allowed us to estimate the motor in-service lifetime.
基金This research was partially supported by a fund from Chinese Academy of Science,and a fund from the Personal Department of the State Council.It is also sponsored by scientific research foundation for returned overseas Chinese Scholars,State Education
文摘In this paper we introduce a primal-dual potential reduction algorithm for positive semi-definite programming. Using the symetric preserving scalings for both primal and dual interior matrices, we can construct an algorithm which is very similar to the primal-dual potential reduction algorithm of Huang and Kortanek [6] for linear programming. The complexity of the algorithm is either O(nlog(X0 · S0/ε) or O(nlog(X0· S0/ε) depends on the value of ρ in the primal-dual potential function, where X0 and S0 is the initial interior matrices of the positive semi-definite programming.
基金Supported by the National Natural Science Foundation of China (Grant No.10671057)
文摘This paper first applies the fuzzy set theory to multi-objective semi-definite program-ming （MSDP）, and proposes the fuzzy multi-objective semi-definite programming （FMSDP） model whose optimal efficient solution is defined for the first time, too. By constructing a membership function, the FMSDP is translated to the MSDP. Then we prove that the optimal efficient solution of FMSDP is consistent with the efficient solution of MSDP and present the optimality condition about these programming. At last, we give an algorithm for FMSDP by introducing a new membership function and a series of transformation.
