Phrenic nerve stimulation(PNS)may preserve diaphragm activation and mitigate multiorgan injury during mechanical ventilation(MV);however,a minimal invasive rat model integrating PNS with MV is lacking.We established a...Phrenic nerve stimulation(PNS)may preserve diaphragm activation and mitigate multiorgan injury during mechanical ventilation(MV);however,a minimal invasive rat model integrating PNS with MV is lacking.We established an omohyoid muscle-based PNS rat model combined with MV.Bilateral nerves were exposed within 20±2 min by transection at the intermediate tendon of omohyoid muscle,minimizing trauma and bleeding.Threshold stimulation(0.6±0.2 mA)correlated with body weight.Ventilator-synchronized stimulation increased compound muscle action potentials by~30%,whereas histology confirmed intact nerve.Physiological parameters remained stable throughout ventilation.This model provides a safe and scalable platform for mechanistic and preclinical studies on PNS-mediated protection against MV-induced organ injury.展开更多
Evaporation duct is an abnormal refractive phenomenon in the marine atmosphere boundary layer. It has been generally accepted that the evaporation duct prominently affects the performance of the electronic equipment o...Evaporation duct is an abnormal refractive phenomenon in the marine atmosphere boundary layer. It has been generally accepted that the evaporation duct prominently affects the performance of the electronic equipment over the sea because of its wide distribution and frequent occurrence. It has become a research focus of the navies all over the world. At present, the diagnostic models of the evaporation duct are all based on the Monin-Obukhov similarity theory, with only differences in the flux and character scale calculations in the surface layer. These models are applicable to the stationary and uniform open sea areas without considering the alongshore effect. This paper introduces the nonlinear factor a and the gust wind item wg into the Babin model, and thus extends the evaporation duct diagnostic model to the offshore area under extremely low wind speed. In addition, an evaporation duct prediction model is designed and coupled with the fifth generation mesoscale model （MMS）. The tower observational data and radar data at the Pingtan island of Fujian Province on May 25-26, 2002 were used to validate the forecast results. The outputs of the prediction model agree with the observations from 0 to 48 h. The relative error of the predicted evaporation duct height is 19.3% and the prediction results are consistent with the radar detection.展开更多
The structure and modeling of a novel unmanned coaxial rotor ducted fan helicopter(RDFH)are introduced,and then,based on the helicopter air dynamics and kinematics principles,a nonlinear model of the coaxial rotor duc...The structure and modeling of a novel unmanned coaxial rotor ducted fan helicopter(RDFH)are introduced,and then,based on the helicopter air dynamics and kinematics principles,a nonlinear model of the coaxial rotor ducted fan helicopter is developed and implemented on the basis of the wind tunnel experiment.After that,the helicopter′s stability and coupling characteristics of manipulation are analyzed through time-domain.Finally,a sliding mode controller(SMC)with boundary layers is developed on a hardware in the loop platform using digital signal processor(DSP)as the flight control computer.The results show that the RDFH′s tracking ability performs well under the use of proposed controller.展开更多
The maritime tropospheric duct is a low-altitude anomalous refractivity structure over the ocean surface,and it can significantly affect the performance of many shore-based/shipboard radar and communication systems.We...The maritime tropospheric duct is a low-altitude anomalous refractivity structure over the ocean surface,and it can significantly affect the performance of many shore-based/shipboard radar and communication systems.We propose the idea that maritime tropospheric ducts can be retrieved from ocean forward-scattered low-elevation global positioning system（GPS） signals.Retrieval is accomplished by matching the measured power patterns of the signals to those predicted by the forward propagation model as a function of the modified refractivity profile.On the basis of a parabolic equation method and bistatic radar equation,we develop such a forward model for computing the trapped propagation characteristics of an ocean forward-scattered GPS signal within a tropospheric duct.A new GPS scattering initial field is defined for this model to start the propagation modeling.A preliminary test on the performance of this model is conducted using measured data obtained from a 2009-experiment in the South China Sea.Results demonstrate that this model can predict GPS propagation characteristics within maritime tropospheric ducts and serve as a forward model for duct inversion.展开更多
AIM:To establish the end-to-end anastomosis (EEA) model of guinea pig bile duct and evaluate the healing process of bile duct.METHODS:Thirty-two male guinea pigs were randomly divided into control group,2-,3-,and 6-mo...AIM:To establish the end-to-end anastomosis (EEA) model of guinea pig bile duct and evaluate the healing process of bile duct.METHODS:Thirty-two male guinea pigs were randomly divided into control group,2-,3-,and 6-mo groups after establishment of EEA model.Histological,immunohistochemical and serologic tests as well as measurement of bile contents were performed.The bile duct diameter and the diameter ratio (DR) were measured to assess the formation of relative stricture.RESULTS:Acute and chronic inflammatory reactions occurred throughout the healing process of bile duct.Serology test and bile content measurement showed no formation of persistent stricture in 6-mo group.The DR revealed a transient formation of relative stricture in 2-mo group in comparation to control group (2.94 ± 0.17 vs 1.89 ± 0.27,P=0.004).However,this relative stricture was released in 6-mo group (2.14 ± 0.18,P=0.440).CONCLUSION:A simple and reliable EEA model of guinea pig bile duct can be established with a good reproducibility and a satisfactory survival rate.展开更多
In order to know the ventilating capacity of imperial smelt furnace(ISF), and increase the output of plumbum, an intelligent modeling method based on gray theory and artificial neural networks(ANN) is proposed, in whi...In order to know the ventilating capacity of imperial smelt furnace(ISF), and increase the output of plumbum, an intelligent modeling method based on gray theory and artificial neural networks(ANN) is proposed, in which the weight values in the integrated model can be adjusted automatically. An intelligent predictive model of the ventilating capacity of the ISF is established and analyzed by the method. The simulation results and industrial applications demonstrate that the predictive model is close to the real plant, the relative predictive error is 0.72%, which is 50% less than the single model, leading to a notable increase of the output of plumbum.展开更多
To improve the operational efficiency of global optimization in engineering, Kriging model was established to simplify the mathematical model for calculations. Ducted coaxial-rotors aircraft was taken as an example an...To improve the operational efficiency of global optimization in engineering, Kriging model was established to simplify the mathematical model for calculations. Ducted coaxial-rotors aircraft was taken as an example and Fluent software was applied to the virtual prototype simulations. Through simulation sample points, the total lift of the ducted coaxial-rotors aircraft was obtained. The Kriging model was then constructed, and the function was fitted. Improved particle swarm optimization(PSO) was also utilized for the global optimization of the Kriging model of the ducted coaxial-rotors aircraft for the determination of optimized global coordinates. Finally, the optimized results were simulated by Fluent. The results show that the Kriging model and the improved PSO algorithm significantly improve the lift performance of ducted coaxial-rotors aircraft and computer operational efficiency.展开更多
BACKGROUND Bile duct ligation(BDL)in animals is a classical method for mimicking cholestatic fibrosis.Although different surgical techniques have been described in rats and rabbits,mouse models can be more cost-effect...BACKGROUND Bile duct ligation(BDL)in animals is a classical method for mimicking cholestatic fibrosis.Although different surgical techniques have been described in rats and rabbits,mouse models can be more cost-effective and reproducible for investigating cholestatic fibrosis.Magnetic resonance imaging(MRI)has made great advances for noninvasive assessment of liver fibrosis.More comprehensive liver fibrotic features of BDL on MRI are important.However,the utility of multiparameter MRI to detect liver fibrosis in a BDL mouse model has not been assessed.AIM To evaluate the correlation between the pathological changes and multiparameter MRI characteristics of liver fibrosis in a BDL mouse model.METHODS Twenty-eight healthy adult male balb/c mice were randomly divided into four groups:sham,week 2 BDL,week 4 BDL,and week 6 BDL.Multiparameter MRI sequences,included magnetic resonance cholangiopancreatography,T1-weighted,T2-weighted,T2 mapping,and pre-and post-enhanced T1 mapping,were performed after sham and BDL surgery.Peripheral blood and liver tissue were collected after MRI.For statistical analysis,Student’s t-test and Pearson’s correlation coefficient were used.RESULTS Four mice died after BDL surgery;seven,six,five and six mice were included separately from the four groups.Signal intensities of liver parenchyma showed no difference on TI-and T2-weighted images.Bile duct volume,ΔT1 value,T2 value,and the rate of liver fibrosis increased steadily in week 2 BDL,week 4 BDL and week 6 BDL groups compared with those in the sham group(P<0.01).Alanine aminotransferase and aspartate transaminase levels initially surged after surgery,followed by a gradual decline over time.Strong correlations were found between bile duct volume(r=0.84),T2 value(r=0.78),ΔT1 value(r=0.62),and hepatic fibrosis rate(all P<0.01)in the BDL groups.CONCLUSION The BDL mouse model induces changes that can be observed on MRI.The MRI parameters correlate with the hepatic fibrosis rate and allow for detection of cholestatic fibrosis.展开更多
This paper proposes an event-triggered stochastic model predictive control for discrete-time linear time-invariant(LTI)systems under additive stochastic disturbances.It first constructs a probabilistic invariant set a...This paper proposes an event-triggered stochastic model predictive control for discrete-time linear time-invariant(LTI)systems under additive stochastic disturbances.It first constructs a probabilistic invariant set and a probabilistic reachable set based on the priori knowledge of system uncertainties.Assisted with enhanced robust tubes,the chance constraints are then formulated into a deterministic form.To alleviate the online computational burden,a novel event-triggered stochastic model predictive control is developed,where the triggering condition is designed based on the past and future optimal trajectory tracking errors in order to achieve a good trade-off between system resource utilization and control performance.Two triggering parametersσandγare used to adjust the frequency of solving the optimization problem.The probabilistic feasibility and stability of the system under the event-triggered mechanism are also examined.Finally,numerical studies on the control of a heating,ventilation,and air conditioning(HVAC)system confirm the efficacy of the proposed control.展开更多
Efforts to find an ideal model for pancreatitis date back to 1960’s. Many models are suggested since then. Every model has its own advantages and disadvantages. Some of these models test etiology while others simulat...Efforts to find an ideal model for pancreatitis date back to 1960’s. Many models are suggested since then. Every model has its own advantages and disadvantages. Some of these models test etiology while others simulate the complications of pancreatitis. An ideal model which by itself demonstrates all aspects of pancreatitis including systemic changes is yet to be described. In this review we tried to gather the basic, easy to construct models.展开更多
Acute Respiratory Distress Syndrome (ARDS) is a major cause of morbidity and has a high rate of mortality. ARDS patients in the intensive care unit (ICU) require mechan-ical ventilation (MV) for breathing support, but...Acute Respiratory Distress Syndrome (ARDS) is a major cause of morbidity and has a high rate of mortality. ARDS patients in the intensive care unit (ICU) require mechan-ical ventilation (MV) for breathing support, but inappropriate settings of MV can lead to ventilator induced lung injury (VILI). Those complications may be avoided by carefully optimizing ventilation parameters through model-based approaches. In this study we introduced a new model of lung mechanics (mNARX) which is a variation of the NARX model by Langdon et al. A multivariate process was undertaken to deter-mine the optimal parameters of the mNARX model and hence, the final structure of the model fit 25 patient data sets and successfully described all parts of the breathing cycle. The model was highly successful in predicting missing data and showed minimal error. Thus, this model can be used by the clinicians to find the optimal patient specific ventilator settings.展开更多
The internal flow field study of car compartments is an important step in railroad vehicle design and optimization. The flow field profile has a significant impact on the temperature distribution and passenger comfort...The internal flow field study of car compartments is an important step in railroad vehicle design and optimization. The flow field profile has a significant impact on the temperature distribution and passenger comfort level. Experimental studies on flow field can yield accurate results but carry a high time and computational cost. In contrast, the numerical simulation method can yield an internal flow field profile in less time than an experimental study. This study aims to improve the computational efficiency of numerical simulation by adapting two simplified models—the porous media model and the porous jump face model—to study the internal flow field of a railroad car compartment. The results provided by both simplified models are compared with the original numerical simulation model and with experimental data. Based on the results, the porous media model has a better agreement with the original model and with the experimental results. The flow field parameters (temperature and velocity) of the porous media model have relatively small numerical errors, with a maximum numerical error of 4.7%. The difference between the numerical results of the original model and those of the porous media model is less than 1%. By replacing the original numerical simulation model with the porous media model, the flow field of subway car compartments can be calculated with a reduction of about 25% in computing resources, while maintaining good accuracy.展开更多
The Miami Isopycnal Coordinate Ocean Model (MICOM) is adopted to simulate the intevdecadal variability in the Pacific Ocean with most emphasis on regime shifts in the North Pacific. The computational domain covers 60&...The Miami Isopycnal Coordinate Ocean Model (MICOM) is adopted to simulate the intevdecadal variability in the Pacific Ocean with most emphasis on regime shifts in the North Pacific. The computational domain covers 60°N to 40°S with an enclosed boundary condition for momentum flux, whereas there are thermohalirie fluxes across the southern end as a restoring term. In addition, sea surface salinity of the model relaxes to the climatological season cycle, which results in climatological fresh water fluxes. Surface forcing functions from January 1945 through December 1998 are derived from the Comprehensive Ocean and Atmospheric Data Set (COADS). Such a numerical experiment reproduces the observed evolution of the interdecadal variability in the heat content over the upper 400-m layer by a two-year lag. Subduction that occurs at the ventilated thermocline in the central North Pacific is also been simulated and the subducted signals propagate from 35°N to 25°N, taking about 8 to 10 years, in agreement with the expendable Bathy Thermograph observation over recent decades. Interdecadal signals take a southwest-ward and downward path rather than westward propagation, meaning they are less associated with the baroclinic planetary waves. During travel, the signals appear to conserve potential vorticity. Therefore, the ventilated thermocline and related subduction are probably the fundamental physics for interdecadal variability in the mid-latitude subtropics of the North Pacific.展开更多
Evaporation duct is an ubiquitous natural phenomenon over the ocean and can be diagnosed by evaporation duct model.The model proposed by Paulus and Jeske and another model established by the American naval postgraduat...Evaporation duct is an ubiquitous natural phenomenon over the ocean and can be diagnosed by evaporation duct model.The model proposed by Paulus and Jeske and another model established by the American naval postgraduate school are the most widely used.They are called PJ model and NPS model,respectively.Two methods are used to investigate the global sensitivity of PJ model and NPS model in China Seas.The first method is based on meteorological and oceanographic observation data in China Seas.Considering the system random error caused by sensor measurement inaccuracies,the mean relative error and mean absolute error are used as criterion for sensitivity analysis.The second method,called Extended Fourier Amplitude Sensitivity Test(EFAST),takes into account the interaction between input parameters and is used for sensitivity analysis.The results show that NPS model is more sensitive to the random errors of sensors than PJ model.The mean relative errors of PJ model and NPS model are 11.43%and 14.81%,respectively.The results of global sensitivity parameter analysis indicate that wind speed is the key factor of PJ model,while all input parameter of NPS model have relatively large total sensitivity index.In addition,sensitivity analysis results confirm that wind speed is one of main driving factors for the formation of evaporation duct.These results are valuable for the selection of diagnosis models for evaporation duct,the evaluation of radio wave propagation in the marine atmospheric surface layer,and the prediction technique of evaporation duct based on numerical weather prediction(NWP)in China seas.展开更多
At high altitudes, an Aviation Oxygen Supply System （AOSS） protects pilots from low pressure and hypoxia by continuously providing oxygen corresponding to the pilots＇ dynamic respiratory properties. An AOSS mainly ...At high altitudes, an Aviation Oxygen Supply System （AOSS） protects pilots from low pressure and hypoxia by continuously providing oxygen corresponding to the pilots＇ dynamic respiratory properties. An AOSS mainly consists of oxygen supercharging machines which are used in a high-altitude flight cabin to supply pressurized oxygen to pilots. Therefore, it is of great significance to study the airflow dynamic characteristics of an AOSS for safe, continuous, and efficient oxygen supply. In this paper, an AOSS is firstly simplified and considered as a mechanical ventilation system. Then, its corresponding mathematical model is constructed. Next, to verify the mathematical model, a prototype AOSS with a lung simulator is proposed for an experimental study. Afterwards, to build a foundation for the optimization of the AOSS, the airflow dynamic characteristics of an aircraft are analyzed, and the effects of key parameters on the respiration system are researched. Through experimental and simulation studies, it can be concluded that the mathematical model is effective. Subsequently, for stability during the respiration process, we consider setting the equivalent throttling areas of the inspiration and expiration pipelines smaller within certain limits; additionally, an excessively high oxygen supply pressure will disturb smooth airflow, and in a low-pressure environment, the pressure can be 84 cmH20 lower than the standard atmospheric pressure. This research can be referred to in the design of an oxygen supply system and the study on optimization of airflow dynamic characteristics.展开更多
Hard coal mines are required to constantly ventilate mine workings to ensure that the air composition is at a certain humidity and temperature level that is comfortable for underground mine workers,especially in deep ...Hard coal mines are required to constantly ventilate mine workings to ensure that the air composition is at a certain humidity and temperature level that is comfortable for underground mine workers,especially in deep deposits.All underground workings,which are part of the mine ventilation network,should be ventilated in a way that allows maintaining proper oxygen concentration not lower than 19%(by volume),and limits concentration of gases in the air such as methane,carbon monoxide or carbon dioxide.The air flow in the mine ventilation network may be disturbed due to the natural convergence(deformation)and lead to change in its original cross-section.Reducing the cross-sectional area of the mining excavation causes local resistances in the air flow and changes in aerodynamic potentials,which leads to emergency states in the mine ventilation network.This paper presents the results of numerical simulations of the influence of gateroad convergence on the ventilation process of a selected part of the mine ventilation network.The gateroad convergence was modelled with the finite element software PHASE 2.The influence of changes in the cross-sectional area of the gateroad on the ventilation process was carried out using the computational fluid dynamics software Ansys-Fluent.展开更多
Ventilation system is significant in underground metal mine of alpine region.Reasonable evaluation of ventilation effectiveness will lead to a practical improvement for the maintenance and management of ventilation sy...Ventilation system is significant in underground metal mine of alpine region.Reasonable evaluation of ventilation effectiveness will lead to a practical improvement for the maintenance and management of ventilation system.However,it is difficult to make an effective evaluation of ventilation system due to the lack of classification criteria with respect to underground metal mine in alpine region.This paper proposes a novel evaluation method called the cloud model-clustering analysis(CMCA).Cloud model(CM)is utilized to process collected data of ventilation system,and they are converted into cloud descriptors by CM.Cloud similarity(CS)based Euclidean distance(ED)is proposed to make clustering analysis of assessed samples.Then the classification of assessed samples will be identified by clustering analysis results.A case study is developed based on CMCA.Evaluation results show that ventilation effectiveness can be well classified.Moreover,CM is used alone to make comparison of evaluation results obtained by CMCA.Then the availability and validity of CMCA is verified.Meanwhile,difference of CS based ED and classical ED is analyzed.Two new clustering analysis methods are introduced to make comparison with CMCA.Then the ability of proposed CMCA to meet evaluation requirements of ventilation system is verified.展开更多
One area of concern in longwall coal mines is the active gob directly behind the longwall face,where high concentrations of methane are likely to accumulate and active roof caving occurs.Using computational fluid dyna...One area of concern in longwall coal mines is the active gob directly behind the longwall face,where high concentrations of methane are likely to accumulate and active roof caving occurs.Using computational fluid dynamics(CFD)to simulate gas flows in and through the gob,most researchers have represented the entire gob as a porous medium governed by Darcy’s law.However,Darcy-type porous flow may not be applicable for the highly porous and unconsolidated fringes of the gob.In addition,porous medium models do not allow for representative combustion modeling to simulate in-gob ignition and flame propagation.This study presents a hybrid approach to modeling the gob using CFD:the outer part of the gob is modeled as discrete objects that simulate coarse rock rubble,while the gob center is modeled as a porous medium.展开更多
Ventilation is an effective solution for improving indoor air quality and reducing airborne transmission.Buildings need sufficient ventilation to maintain a low infection risk but also need to avoid an excessive venti...Ventilation is an effective solution for improving indoor air quality and reducing airborne transmission.Buildings need sufficient ventilation to maintain a low infection risk but also need to avoid an excessive ventilation rate,which may lead to high energy consumption.The Wells-Riley(WR)model is widely used to predict infection risk and control the ventilation rate.However,few studies compared the non-steady-state(NSS)and steady-state(SS)WR models that are used for ventilation control.To fill in this research gap,this study investigates the effects of the mechanical ventilation control strategies based on NSS/SS WR models on the required ventilation rates to prevent airborne transmission and related energy consumption.The modified NSS/SS WR models were proposed by considering many parameters that were ignored before,such as the initial quantum concentration.Based on the NSS/SS WR models,two new ventilation control strategies were proposed.A real building in Canada is used as the case study.The results indicate that under a high initial quantum concentration(e.g.,0.3 q/m^(3))and no protective measures,SS WR control underestimates the required ventilation rate.The ventilation energy consumption of NSS control is up to 2.5 times as high as that of the SS control.展开更多
In order to reveal the influence of forced ventilation on the dispersion of droplets ejected from roadheader-mounted external sprayer,the paper studies the air-flowing field and the droplet distribution under the cond...In order to reveal the influence of forced ventilation on the dispersion of droplets ejected from roadheader-mounted external sprayer,the paper studies the air-flowing field and the droplet distribution under the condition of gentle breeze and normal forced ventilation in heading face using the particle tracking technology of computational fluid dynamics(CFD).The results show that air-flowing tendency in the same section presents great comparability in the period of gentle breeze and forced ventilation,and the difference mainly embodies in the different wind velocity.The influence of ventilation on the dispersion of droplets is faint under the gentle breeze condition.The droplet can be evenly distributed around the cutting head.However,under the normal forced ventilation,a large number of droplets will drift to the return air side.At the same time,droplet clusters are predominantly presented in the lower part of windward side and the middle of the leeward side around the cutting head.In contrast,the droplet concentration in other parts around cutting head decreases a lot and the droplets are unable to form close-grained mist curtain.So the dust escape channel is formed.In addition,the simulation results also reveal that the disturbance of air flow on the droplet distribution can be effectively relieved when using ventilation duct with Coanda effect(VDCE).Field experiment results show that the dust suppression efficiency of total dust and respirable dust increases respectively by 10.5%and 9.3%when using VDCE,which proves that it can weaken the influence of airflow on droplet dispersion.展开更多
基金Outstanding Young Investigator Program of Capital Medical University,Grant/Award Number:A2308。
文摘Phrenic nerve stimulation(PNS)may preserve diaphragm activation and mitigate multiorgan injury during mechanical ventilation(MV);however,a minimal invasive rat model integrating PNS with MV is lacking.We established an omohyoid muscle-based PNS rat model combined with MV.Bilateral nerves were exposed within 20±2 min by transection at the intermediate tendon of omohyoid muscle,minimizing trauma and bleeding.Threshold stimulation(0.6±0.2 mA)correlated with body weight.Ventilator-synchronized stimulation increased compound muscle action potentials by~30%,whereas histology confirmed intact nerve.Physiological parameters remained stable throughout ventilation.This model provides a safe and scalable platform for mechanistic and preclinical studies on PNS-mediated protection against MV-induced organ injury.
文摘Evaporation duct is an abnormal refractive phenomenon in the marine atmosphere boundary layer. It has been generally accepted that the evaporation duct prominently affects the performance of the electronic equipment over the sea because of its wide distribution and frequent occurrence. It has become a research focus of the navies all over the world. At present, the diagnostic models of the evaporation duct are all based on the Monin-Obukhov similarity theory, with only differences in the flux and character scale calculations in the surface layer. These models are applicable to the stationary and uniform open sea areas without considering the alongshore effect. This paper introduces the nonlinear factor a and the gust wind item wg into the Babin model, and thus extends the evaporation duct diagnostic model to the offshore area under extremely low wind speed. In addition, an evaporation duct prediction model is designed and coupled with the fifth generation mesoscale model （MMS）. The tower observational data and radar data at the Pingtan island of Fujian Province on May 25-26, 2002 were used to validate the forecast results. The outputs of the prediction model agree with the observations from 0 to 48 h. The relative error of the predicted evaporation duct height is 19.3% and the prediction results are consistent with the radar detection.
基金supported by the National Natural Science Foundation of China(Nos.6130422361374116+1 种基金61503185)Specialized Research Fund for the Doctoral Program of Higher Education(20123218120015)
文摘The structure and modeling of a novel unmanned coaxial rotor ducted fan helicopter(RDFH)are introduced,and then,based on the helicopter air dynamics and kinematics principles,a nonlinear model of the coaxial rotor ducted fan helicopter is developed and implemented on the basis of the wind tunnel experiment.After that,the helicopter′s stability and coupling characteristics of manipulation are analyzed through time-domain.Finally,a sliding mode controller(SMC)with boundary layers is developed on a hardware in the loop platform using digital signal processor(DSP)as the flight control computer.The results show that the RDFH′s tracking ability performs well under the use of proposed controller.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 61172031 and 41175012)
文摘The maritime tropospheric duct is a low-altitude anomalous refractivity structure over the ocean surface,and it can significantly affect the performance of many shore-based/shipboard radar and communication systems.We propose the idea that maritime tropospheric ducts can be retrieved from ocean forward-scattered low-elevation global positioning system（GPS） signals.Retrieval is accomplished by matching the measured power patterns of the signals to those predicted by the forward propagation model as a function of the modified refractivity profile.On the basis of a parabolic equation method and bistatic radar equation,we develop such a forward model for computing the trapped propagation characteristics of an ocean forward-scattered GPS signal within a tropospheric duct.A new GPS scattering initial field is defined for this model to start the propagation modeling.A preliminary test on the performance of this model is conducted using measured data obtained from a 2009-experiment in the South China Sea.Results demonstrate that this model can predict GPS propagation characteristics within maritime tropospheric ducts and serve as a forward model for duct inversion.
基金Supported by A grant from National 863 Program of China,No.2007AA04Z313
文摘AIM:To establish the end-to-end anastomosis (EEA) model of guinea pig bile duct and evaluate the healing process of bile duct.METHODS:Thirty-two male guinea pigs were randomly divided into control group,2-,3-,and 6-mo groups after establishment of EEA model.Histological,immunohistochemical and serologic tests as well as measurement of bile contents were performed.The bile duct diameter and the diameter ratio (DR) were measured to assess the formation of relative stricture.RESULTS:Acute and chronic inflammatory reactions occurred throughout the healing process of bile duct.Serology test and bile content measurement showed no formation of persistent stricture in 6-mo group.The DR revealed a transient formation of relative stricture in 2-mo group in comparation to control group (2.94 ± 0.17 vs 1.89 ± 0.27,P=0.004).However,this relative stricture was released in 6-mo group (2.14 ± 0.18,P=0.440).CONCLUSION:A simple and reliable EEA model of guinea pig bile duct can be established with a good reproducibility and a satisfactory survival rate.
文摘In order to know the ventilating capacity of imperial smelt furnace(ISF), and increase the output of plumbum, an intelligent modeling method based on gray theory and artificial neural networks(ANN) is proposed, in which the weight values in the integrated model can be adjusted automatically. An intelligent predictive model of the ventilating capacity of the ISF is established and analyzed by the method. The simulation results and industrial applications demonstrate that the predictive model is close to the real plant, the relative predictive error is 0.72%, which is 50% less than the single model, leading to a notable increase of the output of plumbum.
基金Project(2013AA063903)supported by High-tech Research and Development Program of China
文摘To improve the operational efficiency of global optimization in engineering, Kriging model was established to simplify the mathematical model for calculations. Ducted coaxial-rotors aircraft was taken as an example and Fluent software was applied to the virtual prototype simulations. Through simulation sample points, the total lift of the ducted coaxial-rotors aircraft was obtained. The Kriging model was then constructed, and the function was fitted. Improved particle swarm optimization(PSO) was also utilized for the global optimization of the Kriging model of the ducted coaxial-rotors aircraft for the determination of optimized global coordinates. Finally, the optimized results were simulated by Fluent. The results show that the Kriging model and the improved PSO algorithm significantly improve the lift performance of ducted coaxial-rotors aircraft and computer operational efficiency.
基金the Natural Science Foundation of Hunan Province,No.2019JJ40444(to Xiao EH)and 2021JJ30945(to Luo YH).
文摘BACKGROUND Bile duct ligation(BDL)in animals is a classical method for mimicking cholestatic fibrosis.Although different surgical techniques have been described in rats and rabbits,mouse models can be more cost-effective and reproducible for investigating cholestatic fibrosis.Magnetic resonance imaging(MRI)has made great advances for noninvasive assessment of liver fibrosis.More comprehensive liver fibrotic features of BDL on MRI are important.However,the utility of multiparameter MRI to detect liver fibrosis in a BDL mouse model has not been assessed.AIM To evaluate the correlation between the pathological changes and multiparameter MRI characteristics of liver fibrosis in a BDL mouse model.METHODS Twenty-eight healthy adult male balb/c mice were randomly divided into four groups:sham,week 2 BDL,week 4 BDL,and week 6 BDL.Multiparameter MRI sequences,included magnetic resonance cholangiopancreatography,T1-weighted,T2-weighted,T2 mapping,and pre-and post-enhanced T1 mapping,were performed after sham and BDL surgery.Peripheral blood and liver tissue were collected after MRI.For statistical analysis,Student’s t-test and Pearson’s correlation coefficient were used.RESULTS Four mice died after BDL surgery;seven,six,five and six mice were included separately from the four groups.Signal intensities of liver parenchyma showed no difference on TI-and T2-weighted images.Bile duct volume,ΔT1 value,T2 value,and the rate of liver fibrosis increased steadily in week 2 BDL,week 4 BDL and week 6 BDL groups compared with those in the sham group(P<0.01).Alanine aminotransferase and aspartate transaminase levels initially surged after surgery,followed by a gradual decline over time.Strong correlations were found between bile duct volume(r=0.84),T2 value(r=0.78),ΔT1 value(r=0.62),and hepatic fibrosis rate(all P<0.01)in the BDL groups.CONCLUSION The BDL mouse model induces changes that can be observed on MRI.The MRI parameters correlate with the hepatic fibrosis rate and allow for detection of cholestatic fibrosis.
基金supported by the National Nature Science Foundation of China(62073194)the Natural Science Foundation of Shandong Province of China(ZR2023MF028)the Taishan Scholars Program of Shandong Province(tsqn202312008)
文摘This paper proposes an event-triggered stochastic model predictive control for discrete-time linear time-invariant(LTI)systems under additive stochastic disturbances.It first constructs a probabilistic invariant set and a probabilistic reachable set based on the priori knowledge of system uncertainties.Assisted with enhanced robust tubes,the chance constraints are then formulated into a deterministic form.To alleviate the online computational burden,a novel event-triggered stochastic model predictive control is developed,where the triggering condition is designed based on the past and future optimal trajectory tracking errors in order to achieve a good trade-off between system resource utilization and control performance.Two triggering parametersσandγare used to adjust the frequency of solving the optimization problem.The probabilistic feasibility and stability of the system under the event-triggered mechanism are also examined.Finally,numerical studies on the control of a heating,ventilation,and air conditioning(HVAC)system confirm the efficacy of the proposed control.
文摘Efforts to find an ideal model for pancreatitis date back to 1960’s. Many models are suggested since then. Every model has its own advantages and disadvantages. Some of these models test etiology while others simulate the complications of pancreatitis. An ideal model which by itself demonstrates all aspects of pancreatitis including systemic changes is yet to be described. In this review we tried to gather the basic, easy to construct models.
文摘Acute Respiratory Distress Syndrome (ARDS) is a major cause of morbidity and has a high rate of mortality. ARDS patients in the intensive care unit (ICU) require mechan-ical ventilation (MV) for breathing support, but inappropriate settings of MV can lead to ventilator induced lung injury (VILI). Those complications may be avoided by carefully optimizing ventilation parameters through model-based approaches. In this study we introduced a new model of lung mechanics (mNARX) which is a variation of the NARX model by Langdon et al. A multivariate process was undertaken to deter-mine the optimal parameters of the mNARX model and hence, the final structure of the model fit 25 patient data sets and successfully described all parts of the breathing cycle. The model was highly successful in predicting missing data and showed minimal error. Thus, this model can be used by the clinicians to find the optimal patient specific ventilator settings.
文摘The internal flow field study of car compartments is an important step in railroad vehicle design and optimization. The flow field profile has a significant impact on the temperature distribution and passenger comfort level. Experimental studies on flow field can yield accurate results but carry a high time and computational cost. In contrast, the numerical simulation method can yield an internal flow field profile in less time than an experimental study. This study aims to improve the computational efficiency of numerical simulation by adapting two simplified models—the porous media model and the porous jump face model—to study the internal flow field of a railroad car compartment. The results provided by both simplified models are compared with the original numerical simulation model and with experimental data. Based on the results, the porous media model has a better agreement with the original model and with the experimental results. The flow field parameters (temperature and velocity) of the porous media model have relatively small numerical errors, with a maximum numerical error of 4.7%. The difference between the numerical results of the original model and those of the porous media model is less than 1%. By replacing the original numerical simulation model with the porous media model, the flow field of subway car compartments can be calculated with a reduction of about 25% in computing resources, while maintaining good accuracy.
基金supported by the IARC-Frontier Research System for Global Changethe National Natural Science Foundation of China(40136010)the Chinese Academy of Sciences(KZCX2-205 and KZCX2-203).
文摘The Miami Isopycnal Coordinate Ocean Model (MICOM) is adopted to simulate the intevdecadal variability in the Pacific Ocean with most emphasis on regime shifts in the North Pacific. The computational domain covers 60°N to 40°S with an enclosed boundary condition for momentum flux, whereas there are thermohalirie fluxes across the southern end as a restoring term. In addition, sea surface salinity of the model relaxes to the climatological season cycle, which results in climatological fresh water fluxes. Surface forcing functions from January 1945 through December 1998 are derived from the Comprehensive Ocean and Atmospheric Data Set (COADS). Such a numerical experiment reproduces the observed evolution of the interdecadal variability in the heat content over the upper 400-m layer by a two-year lag. Subduction that occurs at the ventilated thermocline in the central North Pacific is also been simulated and the subducted signals propagate from 35°N to 25°N, taking about 8 to 10 years, in agreement with the expendable Bathy Thermograph observation over recent decades. Interdecadal signals take a southwest-ward and downward path rather than westward propagation, meaning they are less associated with the baroclinic planetary waves. During travel, the signals appear to conserve potential vorticity. Therefore, the ventilated thermocline and related subduction are probably the fundamental physics for interdecadal variability in the mid-latitude subtropics of the North Pacific.
基金supported by the National Natural Science Foundation of China (No. 61471329)
文摘Evaporation duct is an ubiquitous natural phenomenon over the ocean and can be diagnosed by evaporation duct model.The model proposed by Paulus and Jeske and another model established by the American naval postgraduate school are the most widely used.They are called PJ model and NPS model,respectively.Two methods are used to investigate the global sensitivity of PJ model and NPS model in China Seas.The first method is based on meteorological and oceanographic observation data in China Seas.Considering the system random error caused by sensor measurement inaccuracies,the mean relative error and mean absolute error are used as criterion for sensitivity analysis.The second method,called Extended Fourier Amplitude Sensitivity Test(EFAST),takes into account the interaction between input parameters and is used for sensitivity analysis.The results show that NPS model is more sensitive to the random errors of sensors than PJ model.The mean relative errors of PJ model and NPS model are 11.43%and 14.81%,respectively.The results of global sensitivity parameter analysis indicate that wind speed is the key factor of PJ model,while all input parameter of NPS model have relatively large total sensitivity index.In addition,sensitivity analysis results confirm that wind speed is one of main driving factors for the formation of evaporation duct.These results are valuable for the selection of diagnosis models for evaporation duct,the evaluation of radio wave propagation in the marine atmospheric surface layer,and the prediction technique of evaporation duct based on numerical weather prediction(NWP)in China seas.
文摘At high altitudes, an Aviation Oxygen Supply System （AOSS） protects pilots from low pressure and hypoxia by continuously providing oxygen corresponding to the pilots＇ dynamic respiratory properties. An AOSS mainly consists of oxygen supercharging machines which are used in a high-altitude flight cabin to supply pressurized oxygen to pilots. Therefore, it is of great significance to study the airflow dynamic characteristics of an AOSS for safe, continuous, and efficient oxygen supply. In this paper, an AOSS is firstly simplified and considered as a mechanical ventilation system. Then, its corresponding mathematical model is constructed. Next, to verify the mathematical model, a prototype AOSS with a lung simulator is proposed for an experimental study. Afterwards, to build a foundation for the optimization of the AOSS, the airflow dynamic characteristics of an aircraft are analyzed, and the effects of key parameters on the respiration system are researched. Through experimental and simulation studies, it can be concluded that the mathematical model is effective. Subsequently, for stability during the respiration process, we consider setting the equivalent throttling areas of the inspiration and expiration pipelines smaller within certain limits; additionally, an excessively high oxygen supply pressure will disturb smooth airflow, and in a low-pressure environment, the pressure can be 84 cmH20 lower than the standard atmospheric pressure. This research can be referred to in the design of an oxygen supply system and the study on optimization of airflow dynamic characteristics.
基金research realized at the Central Mining Institute in Katowice,Poland(No.10030217-152)financed by the Polish Ministry of Science and Higher Education
文摘Hard coal mines are required to constantly ventilate mine workings to ensure that the air composition is at a certain humidity and temperature level that is comfortable for underground mine workers,especially in deep deposits.All underground workings,which are part of the mine ventilation network,should be ventilated in a way that allows maintaining proper oxygen concentration not lower than 19%(by volume),and limits concentration of gases in the air such as methane,carbon monoxide or carbon dioxide.The air flow in the mine ventilation network may be disturbed due to the natural convergence(deformation)and lead to change in its original cross-section.Reducing the cross-sectional area of the mining excavation causes local resistances in the air flow and changes in aerodynamic potentials,which leads to emergency states in the mine ventilation network.This paper presents the results of numerical simulations of the influence of gateroad convergence on the ventilation process of a selected part of the mine ventilation network.The gateroad convergence was modelled with the finite element software PHASE 2.The influence of changes in the cross-sectional area of the gateroad on the ventilation process was carried out using the computational fluid dynamics software Ansys-Fluent.
基金Project(2018YFC0808404)supported by National Key Research and Development Program of China。
文摘Ventilation system is significant in underground metal mine of alpine region.Reasonable evaluation of ventilation effectiveness will lead to a practical improvement for the maintenance and management of ventilation system.However,it is difficult to make an effective evaluation of ventilation system due to the lack of classification criteria with respect to underground metal mine in alpine region.This paper proposes a novel evaluation method called the cloud model-clustering analysis(CMCA).Cloud model(CM)is utilized to process collected data of ventilation system,and they are converted into cloud descriptors by CM.Cloud similarity(CS)based Euclidean distance(ED)is proposed to make clustering analysis of assessed samples.Then the classification of assessed samples will be identified by clustering analysis results.A case study is developed based on CMCA.Evaluation results show that ventilation effectiveness can be well classified.Moreover,CM is used alone to make comparison of evaluation results obtained by CMCA.Then the availability and validity of CMCA is verified.Meanwhile,difference of CS based ED and classical ED is analyzed.Two new clustering analysis methods are introduced to make comparison with CMCA.Then the ability of proposed CMCA to meet evaluation requirements of ventilation system is verified.
基金the National Institute for Occupational Safety and Health(NIOSH)under contract number 211-2014-60050.
文摘One area of concern in longwall coal mines is the active gob directly behind the longwall face,where high concentrations of methane are likely to accumulate and active roof caving occurs.Using computational fluid dynamics(CFD)to simulate gas flows in and through the gob,most researchers have represented the entire gob as a porous medium governed by Darcy’s law.However,Darcy-type porous flow may not be applicable for the highly porous and unconsolidated fringes of the gob.In addition,porous medium models do not allow for representative combustion modeling to simulate in-gob ignition and flame propagation.This study presents a hybrid approach to modeling the gob using CFD:the outer part of the gob is modeled as discrete objects that simulate coarse rock rubble,while the gob center is modeled as a porous medium.
基金Project(RGPIN-2019-05824)supported by the Start-up Fund of Universitéde Sherbrooke and Discovery Grants of Natural Sciences and Engineering Research Council of Canada(NSERC)。
文摘Ventilation is an effective solution for improving indoor air quality and reducing airborne transmission.Buildings need sufficient ventilation to maintain a low infection risk but also need to avoid an excessive ventilation rate,which may lead to high energy consumption.The Wells-Riley(WR)model is widely used to predict infection risk and control the ventilation rate.However,few studies compared the non-steady-state(NSS)and steady-state(SS)WR models that are used for ventilation control.To fill in this research gap,this study investigates the effects of the mechanical ventilation control strategies based on NSS/SS WR models on the required ventilation rates to prevent airborne transmission and related energy consumption.The modified NSS/SS WR models were proposed by considering many parameters that were ignored before,such as the initial quantum concentration.Based on the NSS/SS WR models,two new ventilation control strategies were proposed.A real building in Canada is used as the case study.The results indicate that under a high initial quantum concentration(e.g.,0.3 q/m^(3))and no protective measures,SS WR control underestimates the required ventilation rate.The ventilation energy consumption of NSS control is up to 2.5 times as high as that of the SS control.
基金supported by the Program for Postgraduates Research Innovation in University of Jiangsu Province of China (No.CXLX13_955)the National Natural Science Foundation of China (No.51104153)
文摘In order to reveal the influence of forced ventilation on the dispersion of droplets ejected from roadheader-mounted external sprayer,the paper studies the air-flowing field and the droplet distribution under the condition of gentle breeze and normal forced ventilation in heading face using the particle tracking technology of computational fluid dynamics(CFD).The results show that air-flowing tendency in the same section presents great comparability in the period of gentle breeze and forced ventilation,and the difference mainly embodies in the different wind velocity.The influence of ventilation on the dispersion of droplets is faint under the gentle breeze condition.The droplet can be evenly distributed around the cutting head.However,under the normal forced ventilation,a large number of droplets will drift to the return air side.At the same time,droplet clusters are predominantly presented in the lower part of windward side and the middle of the leeward side around the cutting head.In contrast,the droplet concentration in other parts around cutting head decreases a lot and the droplets are unable to form close-grained mist curtain.So the dust escape channel is formed.In addition,the simulation results also reveal that the disturbance of air flow on the droplet distribution can be effectively relieved when using ventilation duct with Coanda effect(VDCE).Field experiment results show that the dust suppression efficiency of total dust and respirable dust increases respectively by 10.5%and 9.3%when using VDCE,which proves that it can weaken the influence of airflow on droplet dispersion.
