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Intelligent Educational Administration Management System Based on Data Mining Technology
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作者 Xiaofei Yang 《Journal of Contemporary Educational Research》 2025年第6期123-128,共6页
With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the c... With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the campus.They have been applied to teaching,scientific research,student management,and other fields,improving the quality and efficiency of management.This paper mainly studies the intelligent educational administration management system based on data mining technology.Firstly,this paper introduces the application process of data mining technology,and builds an intelligent educational administration management system based on data mining technology.Then,this paper optimizes the application of the Apriori algorithm in educational administration management through transaction compression and frequent sampling.Compared with the traditional Apriori algorithm,the optimized Apriori algorithm in this paper has a shorter execution time under the same minimum support. 展开更多
关键词 Data mining Educational administration management System construction Apriori algorithm
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Pollution Characteristics and Sources of Heavy Metal in the Soil Around a Concentrated Lead and Zinc Mining Area in Guangxi
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作者 LU Yuqiu TANG Xiaohui +5 位作者 XIN Meifen HUANG Yanhong LI Yang WU Hao LUO Dongyuan ZHOU Lang 《有色金属(中英文)》 北大核心 2026年第2期392-411,共20页
39 soil samples surrounding a lead-zinc mining area in Guangxi were collected,and the contents of Pb,Hg,Cd,Cr,As,Cu,Zn,and Ni were determined to investigate the pollution characteristics and sources of heavy metals.Ar... 39 soil samples surrounding a lead-zinc mining area in Guangxi were collected,and the contents of Pb,Hg,Cd,Cr,As,Cu,Zn,and Ni were determined to investigate the pollution characteristics and sources of heavy metals.ArcGIS inverse distance weight difference method was used to analyze the characteristics of pollution distribution,and single-factor pollution index,Nemerow comprehensive pollution index,ground accumulation index,and potential ecological risk index were selected to evaluate the characteristics of heavy metal pollution.Based on correlation analysis,the absolute principal component-multiple linear regression(APCS-MLR)and positive definite matrix factorization(PMF)models were used to analyze the sources of soil heavy metals.The results showed that the average concentrations of all eight heavy metals exceeded both national and Guangxi soil background values.Hg,Cd,and Zn exhibited high variation(greater than 0.5),indicating significant external disturbances,and their spatial distribution was closely related to mining activity locations.The single-factor pollution index evaluation indicated varying degrees of pollution risk for Cd,Zn,and As,with Cd and Zn being the most severe pollutants,as 69.23%and 30.77%of the samples fell into the moderate pollution or higher category.The geoaccumulation index analysis ranked the mean pollution levels of the eight elements as follows:Zn>Cd>Ni>Pb>Cu>Cr>Hg>As,with Cd and Zn showing the most severe contamination,and 51.28%of the samples exhibiting moderate or higher pollution levels.The Nemerow comprehensive pollution index evaluation showed that 74.35%of soil samples were classified as moderate to heavy pollution.The potential ecological risk index assessment indicated significant ecological risks posed by Cd and Zn,with 82.05%and 5.12%of the samples classified as causing strong to extreme ecological risks,respectively.The source apportionment analysis revealed minor differences between the two models.The APCS-MLR model identified three pollution sources and their contribution rates:anthropogenic mining sources(31.13%),parent material sources(40.38%),and unidentified sources(28.49%).The PMF model identified three pollution sources with contribution rates of anthropogenic mining sources(26.10%),parent material sources(46.96%),and a combined traffic and agricultural source(26.61%).Pb,Hg,Cd,and Zn mainly originated from mining activities;Cr,As,and Ni were primarily derived from the parent material,while Cu was predominantly attributed to traffic and agricultural sources.These findings provide a scientific basis for the prevention and control of heavy metal pollution in mining areas. 展开更多
关键词 mining area soil heavy metals pollution characteristics risk assessment source apportionment
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根皮苷通过调节IRS-1/PI3K/Akt信号通路改善T2DM大鼠的糖脂代谢紊乱
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作者 努尔·艾力 曹清雨 +3 位作者 刘欢 何军伟 钟卫红 曹岚 《中国实验方剂学杂志》 北大核心 2026年第3期139-148,共10页
目的:观察根皮苷改善2型糖尿病(T2DM)大鼠肝脏糖脂代谢紊乱的药效学作用,并基于胰岛素受体底物-1(IRS-1)/磷脂酰肌醇3-激酶(PI3K)/蛋白激酶B(Akt)通路探讨其作用机制。方法:采用高脂饲料和链脲佐菌素(STZ)建立T2DM大鼠模型,分为空白组,... 目的:观察根皮苷改善2型糖尿病(T2DM)大鼠肝脏糖脂代谢紊乱的药效学作用,并基于胰岛素受体底物-1(IRS-1)/磷脂酰肌醇3-激酶(PI3K)/蛋白激酶B(Akt)通路探讨其作用机制。方法:采用高脂饲料和链脲佐菌素(STZ)建立T2DM大鼠模型,分为空白组,模型组,二甲双胍组(300 mg·kg^(-1)),根皮苷高、低剂量组(100、25 mg·kg^(-1)),灌胃给药6周,观察大鼠体质量和空腹血糖(FBG)的变化,开展口服葡萄糖耐量实验(OGTT);全自动生化分析仪检测血清中总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)及高密度脂蛋白胆固醇(HDL-C)、糖化血清蛋白(GSP)水平、天冬氨酸氨基转移酶(AST),丙氨酸氨基转移酶(ALT);酶联免疫吸附测定法(ELISA)检测空腹胰岛素(FINS)、白细胞介素(IL)-1β、IL-6、肿瘤坏死因子(TNF)-α;生化法测定肝脏中超氧化物歧化酶(SOD)、丙二醛(MDA)水平;计算胰腺指数、肝脏指数、胰岛素抵抗指数;苏木素-伊红(HE)染色观察大鼠肝脏和胰腺病理变化,免疫荧光法(IF)检测胰腺组织中胰岛素和胰高血糖素的变化;蛋白免疫印迹法(Western blot)检测肝脏组织IRS-1/PI3K/Akt通路相关蛋白及其下游糖原合酶激酶-3β(GSK-3β)和叉头盒转录因子O1(FoxO1)蛋白的表达。结果:与空白组比较,模型组大鼠体质量持续下降、FBG水平明显升高,OGTT血糖曲线下面积(AUC)、GSP、TC、TG、LDL-C、MDA、IL-1β、IL-6、TNF-α水平及胰腺指数、肝脏指数、胰岛素抵抗指数明显升高,HDL-C、SOD、FINS水平明显降低(P<0.05,P<0.01);组织学结果显示,模型组大鼠胰岛萎缩,呈现显著结构紊乱,胰岛素阳性β细胞显著减少(P<0.01),胰高血糖素阳性α细胞显著增加(P<0.01);模型组大鼠肝有炎性细胞浸润,部分细胞坏死,而且肝脏磷酸化(p)-IRS-1/IRS-1、p-GSK-3β/GSK-3β、p-FoxO1/FoxO1蛋白表达显著升高(P<0.01),p-PI3K/PI3K、p-Akt/Akt蛋白表达显著降低(P<0.01)。与模型组比较,各给药组大鼠糖尿病症状有所改善,体质量和FBG变化趋势接近空白组,OGTT-AUC、GSP、TC、TG、LDL-C、MDA、IL-1β、IL-6、TNF-α水平及胰腺指数、肝脏指数、胰岛素抵抗指数明显减少(P<0.05,P<0.01),HDL-C、SOD、FINS水平明显升高(P<0.05,P<0.01);各给药组大鼠胰腺和肝脏病理改变得到有效改善,胰腺中胰岛素阳性β细胞显著增加(P<0.01),胰高血糖素阳性α细胞显著减少(P<0.01),肝脏中p-IRS-1/IRS-1、p-GSK-3β/GSK-3β、p-FoxO1/FoxO1蛋白表达显著减少(P<0.01),p-PI3K/PI3K、p-Akt/Akt蛋白表达显著升高(P<0.01)。结论:根皮苷逆转T2DM大鼠出现的体质量减轻和FBG异常升高,改善血脂、氧化应激、炎症水平,缓解胰岛素抵抗,且对肝脏和胰腺有一定的保护作用,其降糖作用机制可能是通过调节IRS-1/PI3K/Akt信号通络,降低GSK-3β和FoxO1活性,促进肝脏糖原合成,抑制肝脏糖异生功能,进而发挥改善糖脂代谢紊乱。 展开更多
关键词 根皮苷 胰岛素受体底物-1(IRS-1)/磷脂酰肌醇3-激酶(PI3K)/蛋白激酶B(Akt) 2型糖尿病(T2dm) 胰岛素抵抗 糖脂代谢
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Mine surveying science and technology for contemporary and future mining industries
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作者 Zhengfu Bian Qiuzhao Zhang +2 位作者 Runfa Tong Nanshan Zheng Axel Preusse 《International Journal of Mining Science and Technology》 2026年第2期251-275,共25页
Mine surveying is an indispensable and crucial basic technical work in the process of mineral resource development.It plays an important role throughout the entire life cycle of a mine,from exploration,design,construc... Mine surveying is an indispensable and crucial basic technical work in the process of mineral resource development.It plays an important role throughout the entire life cycle of a mine,from exploration,design,construction,and production to closure,and is known as the“eyes of the mine”.With the rapid development of satellite technology,computer science,artificial intelligence,robotics,and spatiotemporal big data,mine surveying science and technology supported by spatial information technology is increasingly playing the role of the“brain of the mine”.This paper systematically summarizes the characteristics of mining surveying science and technology in contemporary and future mining development.First,based on the requirements of safe,efficient,and green development in modern mining,an analysis is conducted on the innovative practices of intelligent mining methods;secondly,it explains the transformation of regional economic and mining economic integration towards lengthening the industrial chain and scientific and technological innovation.Regarding intelligent mining,this paper discusses three technical dimensions:(1)By establishing a spatiotemporal data model of the mine,real-time perception and remote intelligent control of the production system are realized;(2)Based on the transparent mine three-dimensional geological modelling technology,the accuracy of geological condition prediction and the scientific nature of mining decisions are significantly improved;(3)By integrating multi-source remote sensing data and deep learning algorithms,a high-precision coal and rock identification system is constructed.The study further revealed the innovative application value of mine surveying in the post-mining era,including:diversified utilization of underground space in mining areas(tourism development,geothermal energy storage,pumped storage,etc.),multi-platform remote sensing coordinated ecological restoration monitoring,and optimized land space planning in mining areas.Practice has proved that mine surveying technology is an important technical engine for promoting green transformation and high-quality development in resource-based regions,and has irreplaceable strategic significance for achieving coordinated development of energy,economy,and environment. 展开更多
关键词 Mine surveying Intelligent mining Post-mining era Ecological restoration
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Stability of base-exposed backfill roof considering interfaces between adjacent drifts in underhand drift-and-fill mining
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作者 Qinghai Ma Guangsheng Liu +2 位作者 Xiaocong Yang Lijie Guo Andy Fourie 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期214-229,共16页
Stability of base-exposed backfill roof in underhand drift-and-fill mining is crucial for the safety of those working beneath.Given the commonly used primary-and-secondary mining sequence,interfaces are formed between... Stability of base-exposed backfill roof in underhand drift-and-fill mining is crucial for the safety of those working beneath.Given the commonly used primary-and-secondary mining sequence,interfaces are formed between adjacent filled drifts,which can weaken the integrity of the backfill roof.These interfaces also lead to two common drift layouts:aligned drifts and staggered drifts.However,less attention has been paid to the interfaces and the two drift layouts were not adequately distinguished in previous studies.In this paper,the interfaces between filled drifts were firstly considered to investigate the stability of backfill roof.Failure modes and strength requirements of backfill roof in aligned and staggered drifts are comprehensively investigated by FLAC3D,with a focus on considerations of varied shear parameters of the interfaces.Results show that failure modes in aligned drifts transition from block sliding to top caving,bottom caving or sloughing as the interface cohesion increases from zero to at least half of the backfill cohesion.Further increases in interface cohesion allow aligned drifts to behave as if there are no interfaces between them.The critical stability conditions of backfill roof in aligned drifts were mostly determined by the interface strength instead of the backfill strength.However,the stability of backfill roof in staggered drifts is barely affected by the interface strength.The outcomes are expected to provide references for mining engineers to optimize drift layouts and perform cost-effective backfill roof strength design at mines using underhand drift-and-fill mining method. 展开更多
关键词 Base-exposed backfill Interface Failure mode Strength requirement Underhand drift-and-fill mining
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DriftXMiner: A Resilient Process Intelligence Approach for Safe and Transparent Detection of Incremental Concept Drift in Process Mining
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作者 Puneetha B.H Manoj Kumar M.V +1 位作者 Prashanth B.S. Piyush Kumar Pareek 《Computers, Materials & Continua》 2026年第1期1086-1118,共33页
Processes supported by process-aware information systems are subject to continuous and often subtle changes due to evolving operational,organizational,or regulatory factors.These changes,referred to as incremental con... Processes supported by process-aware information systems are subject to continuous and often subtle changes due to evolving operational,organizational,or regulatory factors.These changes,referred to as incremental concept drift,gradually alter the behavior or structure of processes,making their detection and localization a challenging task.Traditional process mining techniques frequently assume process stationarity and are limited in their ability to detect such drift,particularly from a control-flow perspective.The objective of this research is to develop an interpretable and robust framework capable of detecting and localizing incremental concept drift in event logs,with a specific emphasis on the structural evolution of control-flow semantics in processes.We propose DriftXMiner,a control-flow-aware hybrid framework that combines statistical,machine learning,and process model analysis techniques.The approach comprises three key components:(1)Cumulative Drift Scanner that tracks directional statistical deviations to detect early drift signals;(2)a Temporal Clustering and Drift-Aware Forest Ensemble(DAFE)to capture distributional and classification-level changes in process behavior;and(3)Petri net-based process model reconstruction,which enables the precise localization of structural drift using transition deviation metrics and replay fitness scores.Experimental validation on the BPI Challenge 2017 event log demonstrates that DriftXMiner effectively identifies and localizes gradual and incremental process drift over time.The framework achieves a detection accuracy of 92.5%,a localization precision of 90.3%,and an F1-score of 0.91,outperforming competitive baselines such as CUSUM+Histograms and ADWIN+Alpha Miner.Visual analyses further confirm that identified drift points align with transitions in control-flow models and behavioral cluster structures.DriftXMiner offers a novel and interpretable solution for incremental concept drift detection and localization in dynamic,process-aware systems.By integrating statistical signal accumulation,temporal behavior profiling,and structural process mining,the framework enables finegrained drift explanation and supports adaptive process intelligence in evolving environments.Its modular architecture supports extension to streaming data and real-time monitoring contexts. 展开更多
关键词 Process mining concept drift gradual drift incremental drift clustering ensemble techniques process model event log
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TyG指数联合WATCH-DM评分对2型糖尿病患者射血分数保留心力衰竭的预测价值
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作者 邝姣姣 杨庆宇 黄宇理 《中国现代医药杂志》 2026年第1期8-13,共6页
目的评估甘油三酯-葡萄糖(TyG)指数与WATCH-DM评分及其联合应用对2型糖尿病(T2DM)患者发生射血分数保留心力衰竭(HFpEF)的预测价值。方法以2024年8月~2025年8月为调查时段,共纳入蚌埠医科大学第一附属医院收治的T2DM患者308例。所有患... 目的评估甘油三酯-葡萄糖(TyG)指数与WATCH-DM评分及其联合应用对2型糖尿病(T2DM)患者发生射血分数保留心力衰竭(HFpEF)的预测价值。方法以2024年8月~2025年8月为调查时段,共纳入蚌埠医科大学第一附属医院收治的T2DM患者308例。所有患者均采集基线资料并完成心脏超声检查左心室射血分数(LVEF)。依据2024年版中国心力衰竭诊疗指南,将患者分为两组:T2DM组(n=152,LVEF≥50%且无心力衰竭临床表现)和T2DM-HFpEF组(n=156,LVEF≥50%且符合HFpEF诊断标准)。对两组间的TyG指数与WATCH-DM评分进行比较,并运用多因素Logistic回归分析以明确HFpEF发生的独立危险因素。此外,通过绘制受试者工作特征(ROC)曲线,评估上述两个指标及其联合模型对HFpEF的预测价值。结果T2DM-HFpEF组的年龄、空腹血糖(FBG)、甘油三酯(TG)、肌酐(Cr)、血尿素氮(BUN)、TyG指数及WATCH-DM评分均显著高于T2DM组,而左房前后径(LAD)、高密度脂蛋白胆固醇(HDL-C)低于T2DM组(P<0.05)。多因素Logistic回归分析显示,TyG指数(OR=2.159,95%CI:1.391~3.353)和WATCH-DM评分(OR=1.302,95%CI:1.129~1.502)为T2DM患者并发HFpEF的独立危险因素(P<0.05)。ROC曲线分析提示,TyG指数预测HFpEF的曲线下面积(AUC)为0.663,WATCH-DM评分的AUC为0.757,而两者联合的AUC提高至0.776,差异有统计学意义(P<0.05)。结论TyG指数与WATCH-DM评分对T2DM患者并发HFpEF均具有一定的预测价值,二者联合可显著提升预测效能,为筛查高危人群提供了一种简单实用的方法。 展开更多
关键词 甘油三酯-葡萄糖指数 WATCH-dm评分 射血分数保留的心力衰竭 2型糖尿病 预测
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Mineral resources of Asia continent:Resource endowment,mining industry pattern,and contributions to the world economy
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作者 Xi-feng Chen Gang Wang +2 位作者 Yan-xiong Mei Hai-jie Zhao Yan-yun Ma 《China Geology》 2026年第1期1-24,共24页
Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of mineral... Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation. 展开更多
关键词 Mineral resource endowment Minerogenetic series Metallogenic specialization Carbonate-type REE deposits Weathering-type REE deposits Hard rock-type lithium deposits Laterite nickel deposits Crystalline graphite deposits Magmatic nickel deposits Significant metallogenic belt mining industry development pattern Mineral exploration and exploitation World economy Contribution Asia continent
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Remediation of in-situ Leach Mining Contaminated Soil by Amendment-plant Synergism 被引量:1
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作者 冯秀娟 朱易春 +4 位作者 阎思诺 鄱洋 马彩云 高咪 张素贞 《Agricultural Science & Technology》 CAS 2014年第1期63-70,78,共9页
This study aimed to remediate in-situ leach mining contaminated soil by amendment-plant synergism. The results showed that plant species exhibited ex-tremely significant effects on the concentration of nitrate nitroge... This study aimed to remediate in-situ leach mining contaminated soil by amendment-plant synergism. The results showed that plant species exhibited ex-tremely significant effects on the concentration of nitrate nitrogen; to be specific, the concentration of nitrate nitrogen in soil planted with wheat was reduced from 692.19 mg/kg to lower than 100 mg/kg; when the mass ratio of amendment to soil reached 3:50 and the amendment particle size was 1-2 mm, the concentration of nitrate ni-trogen in soil planted with wheat was reduced to 43 mg/kg. The amendment type exhibited extremely significant effects on the concentration of ammonium nitrogen; to be specific, when the mass ratio of amendment to soil reached 10:50, the concen-tration of ammonium nitrogen in soil added with 2-3 mm zeolite was reduced from 23 593.75 to 3 300 mg/kg on day 15. Amendments and plants mainly exhibited desorption performance for sulfate radical in soil, and the amendment type extreme-ly significantly affected the concentration of sulfate radical; to be specific, the con-centration of sulfate radical in soil added with limestone increased from 370 mg/kg to 900 mg/kg on day 7. 展开更多
关键词 In-situ leach mining of rare earth mine Leaching reagent ammonia sul-fate Soil contamination Amendment-plant synergism REMEDIATION
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沙格列汀与达格列净分别联合阿法骨化醇对T2DM性骨质疏松症患者疗效和25-羟维生素D水平,骨代谢指标的影响 被引量:2
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作者 吴静 姜惠 +2 位作者 王丽 束燕雯 孙璐 《现代生物医学进展》 2025年第3期468-473,共6页
目的:对比研究沙格列汀与达格列净分别联合阿法骨化醇对T2DM性骨质疏松症(DOP)患者疗效、25-羟维生素D[25(OH)D]及骨代谢指标的影响。方法:选入2021.4~2024.4收治的DOP患者84例,分为沙格列汀组(42例)和达格列净组(42例),两组均联合阿法... 目的:对比研究沙格列汀与达格列净分别联合阿法骨化醇对T2DM性骨质疏松症(DOP)患者疗效、25-羟维生素D[25(OH)D]及骨代谢指标的影响。方法:选入2021.4~2024.4收治的DOP患者84例,分为沙格列汀组(42例)和达格列净组(42例),两组均联合阿法骨化醇治疗。比较临床疗效、25(OH)D水平及骨代谢指标。结果:(1)两组治疗后FPG、2hPG、HbA1c降低(P<0.05),组间比较无差异(P>0.05)。(2)两组治疗后BMD、血清25(OH)D和OC升高,PINP降低(P<0.05),而沙格列汀组升高/降低幅度明显大于达格列净组(P<0.05);(3)沙格列汀组治疗总有效率显著高于达格列净组(95.24%vs.76.19%,P<0.05)。(4)两组均未见明显不良反应。结论:沙格列汀与达格列净均可有效控制血糖水平,而前者在增加BMD、改善骨代谢指标、提高DOP整体疗法方面更具优势。 展开更多
关键词 沙格列汀 达格列净 阿法骨化醇 T2dm 骨质疏松症 疗效 25(OH)D 骨代谢指标
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Regional assessment of cadmium pollution in agricultural lands and the potential health risk related to intensive mining activities: A case study in Chenzhou City, China 被引量:36
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作者 ZHAI Limei LIAO Xiaoyong +4 位作者 CHEN Tongbin YAN Xiulan XIE Hua WU Bin WANG Lixia 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2008年第6期696-703,共8页
The purpose of this study was to assess the extent of cadmium (Cd) contamination in agricultural soil and its potential risk for people. Soils, rice, and vegetables from Chenzhou City, Southern China were sampled an... The purpose of this study was to assess the extent of cadmium (Cd) contamination in agricultural soil and its potential risk for people. Soils, rice, and vegetables from Chenzhou City, Southern China were sampled and analyzed. In the surface soils, the 95% confidence interval for the mean concentration of Cd varied between 2.72 and 4.83 mg/kg (P 〈 0.05) in the survey, with a geometric mean concentration of 1.45 mg/kg. Based on the GIS map, two hot spot areas of Cd in agricultural soils with high Cd concentrations were identified to be located around the Shizhuyuan, Jinshiling, and Yaogangxian mines, and the Baoshan and Huangshaping mines, in the center of the city. About 60% of the total investigated area, where the agricultural soil Cd concentration is above 1 mg/kg, is distributed in a central belt across the region. The critical distances, at which the soil Cd concentration were increased by the mining activities, from the mines of the soils were 23 km for the Baoshan mine, 46 km for the Huangshaping mine, and 63 km for the Shizhuyuan mine, respectively. These are distances calculated from models. The Cd concentrations in rice samples ranged from 0.01 to 4.43 mg/kg and the mean dietary Cd intake from rice for an adult was 191 μg/d. Results of risk indexes showed that soil Cd concentrations possessed risks to local residents whose intake of Cd from rice and vegetables grown in soils in the vicinity of the mine was 596 μg/d. 展开更多
关键词 CAdmIUM health risk mining activities RICE soil contamination VEGETABLE
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基于DM2的异构数据一致性校验方法研究
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作者 朱文 方文崇 +3 位作者 周志峰 李文朝 攀腾飞 吴海勇 《自动化技术与应用》 2025年第2期75-79,共5页
随着物联网技术的快速发展,网络中存在大量的异构数据库,其异构性表现在多个方面。当数据库模式不同时,产生的数据类型也不尽相同,为保证数据的一致性,研究基于DM2的异构数据一致性校验方法。在异构系统中捕获异构数据包,通过良性和恶... 随着物联网技术的快速发展,网络中存在大量的异构数据库,其异构性表现在多个方面。当数据库模式不同时,产生的数据类型也不尽相同,为保证数据的一致性,研究基于DM2的异构数据一致性校验方法。在异构系统中捕获异构数据包,通过良性和恶意线程运行模式,分析异构数据的特点。划分异构数据类型,处理并计算数据值。基于DM2技术构建输出图,设定一致性校验原则。以校验原则为基础,构建一致性验证矩阵,实现异构数据的一致性校验。实验结果表明:在不同数据源的并发过程中,所提方法能够有效召回错误数据记录,且召回正确率均在95%以上,具有较好的应用效果。 展开更多
关键词 异构数据 一致性校验 校验方法 dm2技术
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超宽阻带DMS微带低通滤波器设计与神经网络优化
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作者 杨维明 杨武韬 +2 位作者 姜立新 王炳辉 潘东阳 《电子器件》 2025年第5期968-973,共6页
针对微带低通滤波器宽阻带、低损耗及小型化要求难以兼顾的问题,采用加载DMS单元并结合BP神经网络算法进行优化设计的方法加以解决。首先在高低阻抗线微带滤波器的微带金属面引入T型DMS单元,采用BP神经网络算法对DMS单元进行结构优化,... 针对微带低通滤波器宽阻带、低损耗及小型化要求难以兼顾的问题,采用加载DMS单元并结合BP神经网络算法进行优化设计的方法加以解决。首先在高低阻抗线微带滤波器的微带金属面引入T型DMS单元,采用BP神经网络算法对DMS单元进行结构优化,使滤波器的通带性能明显改善、体积明显减小;接着在滤波器接地面上蚀刻DGS单元,并对微带并联枝节的矩形结构单元进行优化,进一步提高滤波器阻带的谐波抑制能力。测试结果表明,优化设计后滤波器的通带截止频率为2 GHz,通带插入损耗≤0.1dB、回波损耗S_(11)降低到-15.49 dB,阻带抑制S_(21)低于-20 dB的频率范围为2.73 GHz~15.39 GHz,而面积为20 mm×18.75 mm,满足某L波段雷达抗谐波干扰、低损耗和小型化的要求。 展开更多
关键词 微带低通滤波器 超宽阻带 dmS单元 神经网络优化
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Optimal control of cobalt crust seabedmining parameters based on simulated annealing genetic algorithm 被引量:2
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作者 夏毅敏 张刚强 +2 位作者 聂四军 卜英勇 张振华 《Journal of Central South University》 SCIE EI CAS 2011年第3期650-657,共8页
Under the condition of the designated collection ratio and the interfused ratio of mullock, to ensure the least energy consumption, the parameters of collecting head (the feed speed, the axes height of collecting hea... Under the condition of the designated collection ratio and the interfused ratio of mullock, to ensure the least energy consumption, the parameters of collecting head (the feed speed, the axes height of collecting head, and the rotate speed) are chosen as the optimized parameters. According to the force on the cutting pick, the collecting size of the cobalt crust and bedrock and the optimized energy consumption of the collecting head, the optimized design model of collecting head is built. Taking two hundred groups seabed microtopography for grand in the range of depth displacement from 4.5 to 5.5 era, then making use of the improved simulated annealing genetic algorithm (SAGA), the corresponding optimized result can be obtained. At the same time, in order to speed up the controlling of collecting head, the optimization results are analyzed using the regression analysis method, and the conclusion of the second parameter of the seabed microtopography is drawn. 展开更多
关键词 cobalt crust mining parameter specific energy consumption simulated annealing genetic algorithm
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基于经典Hippo信号通路探索Neu-P11改善T2DM胰岛素抵抗的机制 被引量:1
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作者 李秀平 蔡世昌 +3 位作者 谢柳 贺娟 陈玲群 孟雯雯 《中国药理学通报》 CAS 北大核心 2025年第1期199-200,共2页
褪黑素(melatonin,Mel)是主要由松果体释放的一种循环激素,有一定的抗糖尿病作用,但其进入人体后,代谢较快,半衰期短,直接药用效果不明显,提取与合成较难,剂量过高还会产生副作用。Neu-P11是一种新式褪黑素非选择性受体激动剂,体外合成... 褪黑素(melatonin,Mel)是主要由松果体释放的一种循环激素,有一定的抗糖尿病作用,但其进入人体后,代谢较快,半衰期短,直接药用效果不明显,提取与合成较难,剂量过高还会产生副作用。Neu-P11是一种新式褪黑素非选择性受体激动剂,体外合成容易,作用时间持久,副作用小,能代替褪黑素,与其受体结合,发挥生物学作用[1]。 展开更多
关键词 Hippo信号通路 褪黑素 Neu-P11 dm T2dm 胰岛素抵抗
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Mobile Data Mining-Based Services on the Base of Mobile Device Management (MDM) System
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作者 Mazin Omar Khairo 《Journal of Signal and Information Processing》 2014年第3期89-96,共8页
Client software on mobile devices that can cause the remote control perform data mining tasks and show production results is significantly added the value for the nomadic users and organizations that need to perform d... Client software on mobile devices that can cause the remote control perform data mining tasks and show production results is significantly added the value for the nomadic users and organizations that need to perform data analysis stored in the repository, far away from the site, where users work, allowing them to generate knowledge regardless of their physical location. This paper presents new data analysis methods and new ways to detect people work location via mobile computing technology. The growing number of applications, content, and data can be accessed from a wide range of devices. It becomes necessary to introduce a centralized mobile device management. MDM is a KDE software package working with enterprise systems using mobile devices. The paper discussed the design system in detail. 展开更多
关键词 Data mining Mobile Device MANAGEMENT USER RECOMMENDATION KDE Software PACKAGE
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基于TLR4/MyD88/NF-κB信号通路探讨梓醇对T2DM大鼠肾损伤的保护作用 被引量:1
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作者 周宏园 朱勤伟 彭淑芹 《齐齐哈尔医学院学报》 2025年第12期1107-1112,共6页
目的分析基于TLR4/MyD88/NF-κB信号通路探讨梓醇对T2DM大鼠肾损伤的保护作用。方法选择SPF级雄性SD大鼠50只,造模过程中有10只大鼠造模失败,采用随机数表法将大鼠分为正常组(control,10只)和模型组、西药组、梓醇组四组,每组各10只。... 目的分析基于TLR4/MyD88/NF-κB信号通路探讨梓醇对T2DM大鼠肾损伤的保护作用。方法选择SPF级雄性SD大鼠50只,造模过程中有10只大鼠造模失败,采用随机数表法将大鼠分为正常组(control,10只)和模型组、西药组、梓醇组四组,每组各10只。比较各组大鼠干预前后空腹血糖、肾功能指标以及TLR4、MyD88、NF-κB蛋白表达量。结果干预4周后,模型组和西药组、梓醇组FPG、FINS、HOMA-IR水平比较,差异均具有统计学意义(P<0.05);模型组、西药组和梓醇组FPG、FINS、HOMAIR均高于正常组,差异均具有统计学意义(P<0.05);西药组和梓醇组FPG、FINS、HOMAIR低于模型组,差异具有统计学意义(P<0.05);且梓醇组FPG、FINS、HOMAIR低于西药组,差异均具有统计学意义(P<0.05);干预4周后,模型组和西药组、梓醇组BUN、Scr及24 h mALB水平比较,差异均具有统计学意义(P<0.05);模型组、西药组和梓醇组BUN、Scr及24 h mALB均高于正常组,差异均具有统计学意义(P<0.05);西药组和梓醇组BUN、Scr及24 h mALB低于模型组,差异具有统计学意义(P<0.05);且梓醇组BUN、Scr及24 h mALB低于西药组,差异均具有统计学意义(P<0.05);模型组与正常组相比,大鼠肾组织TLR4、MyD88、NF-κB的表达明显上调;与模型组相比,西药组、梓醇组的肾组织TLR4、MyD88、NF-κB的表达明显下调。模型组、西药组、梓醇组TLR4、MyD88、NF-κB的mRNA相对表达量均明显高于正常组,且西药组、梓醇组TLR4、MyD88、NF-κB的mRNA相对表达量明显低于模型组,差异具有统计学意义(P<0.05);梓醇组TLR4、MyD88、NF-κB的mRNA相对表达量低于西药组,差异具有统计学意义(P<0.05)。结论梓醇对2型糖尿病大鼠肾损伤有一定保护作用,可能与抑制TLR4/MyD88/NF-κB信号通路异常激活有关。 展开更多
关键词 TLR4 MYD88 NF-ΚB 通路 梓醇 T2dm 肾损伤
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磁共振IDEAL-IQ定量预测T2DM合并骨质疏松症患者骨折风险的价值
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作者 马娟 马依迪丽·尼加提 +6 位作者 马海婷 任镇伟 仇馨悦 栾丽 张梅 袁雁 郭辉 《中国CT和MRI杂志》 2025年第10期183-185,共3页
目的分析磁共振(MRI)非对称回波的最小二程估算法迭代水脂分离(IDEAL-IQ)预测T2DM合并骨质疏松症患者骨折风险的价值。方法选取2022年7月至2024年8月新疆医科大学附属中医医院影像中心收治的T2DM合并骨质疏松症患者148例为研究对象,依... 目的分析磁共振(MRI)非对称回波的最小二程估算法迭代水脂分离(IDEAL-IQ)预测T2DM合并骨质疏松症患者骨折风险的价值。方法选取2022年7月至2024年8月新疆医科大学附属中医医院影像中心收治的T2DM合并骨质疏松症患者148例为研究对象,依据是否发生椎体压缩性骨折分为骨折组(n=85)、无骨折组(n=63),均接受脊柱MRI IDEAL-IQ检查,测定L_(1-5)各椎体脂肪分数值(FF)及L_(1-5)椎体平均FF,比较骨折组、无骨折组骨代谢生化指标[25-(OH)D水平、β-胶原特殊序列(β-CTX)、Ⅰ型胶原氨基端延长肽(PⅠNP)]及骨密度(BMD)与IDEAL-IQ定量参数,分析FF值与各指标相关性,绘制受试者工作特征曲线(ROC)分析FF值对T2DM合并骨质疏松症患者骨折风险的预测价值。结果骨折组血清25-(OH)D、BMD低于无骨折组,而β-CTX、PⅠNP高于无骨折组(P<0.05);骨折组L1FF值、L2FF值及L_(1-5)椎体平均FF值均高于无骨折组(P<0.05);Pearson相关分析发现,T2DM合并骨质疏松症患者L1FF值、L2FF值及L_(1-5)椎体平均FF值均与25-(OH)D、BMD呈负相关,而与β-CTX、PⅠNP呈正相关(P<0.05);ROC显示,L1FF值、L2FF值及L_(1-5)椎体平均FF值预测T2DM合并骨质疏松症患者骨折风险的曲线下面积分别为0.791、0.806、0.876。结论MRI IDEAL-IQ定量预测T2DM合并骨质疏松症患者骨折风险的价值较高,值得在临床推广实践。 展开更多
关键词 磁共振 IDEAL-IQ T2dm 骨质疏松症 骨折风险
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黄芪葛根配伍通过调控线粒体自噬抑制铁死亡改善T2DM大鼠IR的机制研究
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作者 魏爽 章文春 +2 位作者 邢欢 西旺 郝峰 《中国医院药学杂志》 北大核心 2025年第9期1006-1014,共9页
目的:探讨黄芪葛根配伍改善2型糖尿病(type 2 diabetes mellitus,T2DM)大鼠胰岛素抵抗(insulin resistance,IR)的作用机制。方法:将SD大鼠随机分为正常组与造模组,造模组采用高脂饮食联合STZ尾静脉注射法建立T2DM IR模型,成模大鼠随机... 目的:探讨黄芪葛根配伍改善2型糖尿病(type 2 diabetes mellitus,T2DM)大鼠胰岛素抵抗(insulin resistance,IR)的作用机制。方法:将SD大鼠随机分为正常组与造模组,造模组采用高脂饮食联合STZ尾静脉注射法建立T2DM IR模型,成模大鼠随机分为模型(Model)、T2DM IR+黄芪葛根配伍(T2DM IR+QG)、T2DM IR+铁死亡抑制剂(T2DM IR+Fer-1)、T2DM IR+黄芪葛根配伍+铁死亡诱导剂(T2DM IR+QG+Erastin)、T2DM IR+线粒体自噬激动剂(T2DM IR+CCCP)、T2DM IR+黄芪葛根配伍+线粒体自噬抑制剂(T2DM IR+QG+3-MA)6组。使用血糖仪检测大鼠空腹血糖(FBG)水平、酶联免疫吸附法(ELISA)检测空腹胰岛素(FINS)水平并依据FBG及FINS值计算胰岛素敏感指数(ISI)及胰岛素抵抗指数(HOMA-IR);比色法检测肝组织超氧化物歧化酶(SOD)、谷胱甘肽(GSH)、丙二醛(MDA)、铁离子(Fe2+)、铁(Fe)水平;流式细胞仪检测肝组织活性氧簇(ROS)水平;微板法检测肝脏组织还原型辅酶Ⅱ/辅酶Ⅱ(NADPH/NADP+)水平及极谱法检测线粒体RCR、ATP、MMP水平;透射电镜观察肝脏线粒体形态结构;蛋白免疫印迹法(Western blot)检测铁死亡及线粒体自噬相关蛋白水平。结果:与正常组相比,Model组FBG、FINS、MDA、ROS水平,HOMA-IR值,Fe2+及Fe含量,LC3Ⅱ、PINK1、Parkin、P62、ACSL4蛋白表达,以及LC3Ⅱ/LC3Ⅰ、NADPH/NADP+水平升高(P<0.05);GSH、SOD水平,胰岛素敏感指数对数(IAI)值,MMP、ATP、RCR水平,TOM20、TIM23、GPX4、FTH1、ACSL3、FTMT、xCT表达显著降低(P<0.01)。与Model组相比,T2DM IR+QG、T2DM IR+Fer-1及T2DM IR+CCCP组FBG、FINS、MDA、ROS、Fe2+及Fe水平,HOMAIR值,ACSL4表达,NADPH/NADP+水平降低(P<0.05);GPX4、FTH1、ACSL3、GSH、SOD、xCT水平及IAI值升高(P<0.05);T2DM IR+QG组FTMT表达显著升高(P<0.01);T2DM IR+CCCP组TOM20、P62蛋白表达降低(P<0.05);MMP、ATP、RCR水平,LC3Ⅱ、PINK1、Parkin蛋白表达及LC3Ⅱ/LC3Ⅰ水平显著升高(P<0.01)。透射电镜观察见正常组大鼠肝脏组织中线粒体大小、形态良好且分布于整个细胞质中,线粒体内外膜完整光滑,内部基质存在且分布均匀;模型组中见线粒体体积缩小,存在核周聚集,外膜不规则或碎裂。与模型组相比,T2DM IR+QG、T2DM IR+Fer-1与T2DM IR+CCCP组正常形态的线粒体比例明显增多,结构与分布整体有显著改善;而T2DM IR+QG+Erastin及T2DM IR+QG+3-MA组中线粒体形态结构未见改善,且损害更加严重。结论:黄芪葛根配伍提高胰岛素敏感性,改善IR,防治T2DM的作用可能是通过PINK1/Parkin通路调控线粒体自噬抑制铁死亡机制实现的。 展开更多
关键词 黄芪葛根配伍 线粒体自噬 铁死亡 PINK1/Parkin通路 T2dm 胰岛素抵抗
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基于XGBoost算法的T2DM合并颈动脉斑块风险预测及致因研究
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作者 李桃 徐映梅 蒋伏松 《医疗卫生装备》 2025年第12期9-14,共6页
目的:基于梯度提升决策树的集成学习(eXtreme gradient boosting,XGBoost)算法进行2型糖尿病(type 2 diabetes mellitus,T2DM)合并颈动脉斑块的风险预测及影响因素研究,以期为该疾病的发现、预防和治疗提供有价值的指导。方法:收集2019... 目的:基于梯度提升决策树的集成学习(eXtreme gradient boosting,XGBoost)算法进行2型糖尿病(type 2 diabetes mellitus,T2DM)合并颈动脉斑块的风险预测及影响因素研究,以期为该疾病的发现、预防和治疗提供有价值的指导。方法:收集2019—2023年上海市某三甲医院3 707例T2DM患者的临床数据,包括2 359例横断面数据和1 348例纵向随访数据。采用方差分析法和Pearson相关系数法对数据进行交叉验证和变量筛选。基于横断面数据和纵向随访数据,采用XGBoost算法构建预测模型,并与人工神经网络、支持向量机以及高斯朴素贝叶斯3种机器学习模型进行对比以验证XGBoost模型的性能;采用沙普利加法解释(Shapley additive explanations,SHAP)分析模型的可解释性,采用特征权重图分析模型中各特征的重要性,并基于横断面数据和纵向随访数据对影响T2DM合并颈动脉斑块的因素进行对比。结果:XGBoost模型在横断面数据中准确率为0.77、精确率为0.62、召回率为0.59、F1分数为0.51,在纵向随访数据中准确率为0.75、精确率为0.57、召回率为0.68、F1分数为0.62。综合2类数据下的性能表现,XGBoost模型整体预测效果优于人工神经网络、支持向量机以及高斯朴素贝叶斯3种机器学习模型。SHAP值散点图和特征权重图显示,口干、高血压和年龄是影响T2DM合并颈动脉斑块的主要因素。结论:通过XGBoost算法可以实现对T2DM合并颈动脉斑块的预测。临床实践中应对影响该疾病的相关因素加强监测、评估和干预,以降低罹患该疾病的可能性。 展开更多
关键词 T2dm 颈动脉斑块 XGBoost算法 风险预测 影响因素
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