Accurately diagnosing Alzheimer's disease is essential for improving elderly health.Meanwhile,accurate prediction of the mini-mental state examination score also can measure cognition impairment and track the prog...Accurately diagnosing Alzheimer's disease is essential for improving elderly health.Meanwhile,accurate prediction of the mini-mental state examination score also can measure cognition impairment and track the progression of Alzheimer's disease.However,most of the existing methods perform Alzheimer's disease diagnosis and mini-mental state examination score prediction separately and ignore the relation between these two tasks.To address this challenging problem,we propose a novel multi-task learning method,which uses feature interaction to explore the relationship between Alzheimer's disease diagnosis and minimental state examination score prediction.In our proposed method,features from each task branch are firstly decoupled into candidate and non-candidate parts for interaction.Then,we propose feature sharing module to obtain shared features from candidate features and return shared features to task branches,which can promote the learning of each task.We validate the effectiveness of our proposed method on multiple datasets.In Alzheimer's disease neuroimaging initiative 1 dataset,the accuracy in diagnosis task and the root mean squared error in prediction task of our proposed method is 87.86%and 2.5,respectively.Experimental results show that our proposed method outperforms most state-of-the-art methods.Our proposed method enables accurate Alzheimer's disease diagnosis and mini-mental state examination score prediction.Therefore,it can be used as a reference for the clinical diagnosis of Alzheimer's disease,and can also help doctors and patients track disease progression in a timely manner.展开更多
Purpose： To investigate the profiles of cognitive impairment through Montreal Cognitive Assessment （MoCA） and Mini-Mental State Examination （MMSE） in patients with chronic traumatic brain injury （TBI） or stroke...Purpose： To investigate the profiles of cognitive impairment through Montreal Cognitive Assessment （MoCA） and Mini-Mental State Examination （MMSE） in patients with chronic traumatic brain injury （TBI） or stroke and to evaluate the sensitivity of the two scales in patients with TBI. Methods： In this cohort study, a total of 230 patients were evaluated, including TBI group （n = 103） and stroke group （n - 127）. The cognitive functions of two groups were evaluated by designated specialists using MoCA （Beijing version） and MMSE （Chinese version）. Results： Compared with the patients with stroke, the patients with TBI received significantly lower score in orientation subtest and recall subtest in both tests. MoCA abnormal rates in the TBI group and stroke group were 94.17% and 86.61% respectively, while MMSE abnormal rates were 69.90% and 57.48%, respectively. In the TBI group, 87.10% patients with normal MMSE score had abnormal MoCA score and in the stroke group, about 70.37% patients with normal MMSE score had abnormal MoCA score. The diagnostic consistency of two scales in the TBI group and the stroke group were 72% and 69%, re.spectively. Conclusion： In our rehabilitation center, patients with TBI may have mare extensive and severe cognitive impairments than patients with stroke, prominently in orientation and recall domain. In screening post- TBI cognitive impairment, MoCA tends to be more sensitive than MIV[SE.展开更多
目的研究快乐感知训练团体护理模式用于老年痴呆伴发抑郁情绪患者的价值。方法观察我院在2022年1月~2023年1月就诊的老年痴呆伴发抑郁情绪患者80例,按抽签法分为观察组40例及对照组40例。对照组采取常规护理,观察组在对照组的基础上进...目的研究快乐感知训练团体护理模式用于老年痴呆伴发抑郁情绪患者的价值。方法观察我院在2022年1月~2023年1月就诊的老年痴呆伴发抑郁情绪患者80例,按抽签法分为观察组40例及对照组40例。对照组采取常规护理,观察组在对照组的基础上进行快乐感知训练团体护理。比较两组心理状态,记录两组焦虑自评量表(Self-Rating Anxiety Scale,SAS)、抑郁自评量表(Self-Rating Dpression Scale,SDS)、简易精神状态评价量表(Mini-Mental State Examination,MMSE)、临床痴呆评定量表(Clinical Dementia Rating,CDR)、日常生活能力量表(Activity of Daily Living Scale,ADL)及健康状况调查简表(the MOS item short from health survey,SF-36)评分,收集患者家属满意度。结果干预后两组患者SAS、SDS评分较干预前显著下降,且观察组低于对照组(P<0.05);干预后两组MMSE、ADL、SF-36评分较干预前上升,CDR评分下降,观察组MMSE、ADL、SF-36高于对照组,CDR低于对照组(P<0.05);观察组患者家属满意度高于对照组(P<0.05)。结论快乐感知训练团体护理模式用于老年痴呆伴发抑郁情绪患者的临床价值高,能够有效缓解患者焦虑、抑郁情绪,适用于临床。展开更多
基金supported in part by the National Natural Science Foundation of China(No.62172444)Natural Science Foundation of Hunan Province(No.2022JJ30753)+1 种基金Central South University Innovation-Driven Research Programme(No.2023CXQD018)High Performance Computing Center of Central South University.
文摘Accurately diagnosing Alzheimer's disease is essential for improving elderly health.Meanwhile,accurate prediction of the mini-mental state examination score also can measure cognition impairment and track the progression of Alzheimer's disease.However,most of the existing methods perform Alzheimer's disease diagnosis and mini-mental state examination score prediction separately and ignore the relation between these two tasks.To address this challenging problem,we propose a novel multi-task learning method,which uses feature interaction to explore the relationship between Alzheimer's disease diagnosis and minimental state examination score prediction.In our proposed method,features from each task branch are firstly decoupled into candidate and non-candidate parts for interaction.Then,we propose feature sharing module to obtain shared features from candidate features and return shared features to task branches,which can promote the learning of each task.We validate the effectiveness of our proposed method on multiple datasets.In Alzheimer's disease neuroimaging initiative 1 dataset,the accuracy in diagnosis task and the root mean squared error in prediction task of our proposed method is 87.86%and 2.5,respectively.Experimental results show that our proposed method outperforms most state-of-the-art methods.Our proposed method enables accurate Alzheimer's disease diagnosis and mini-mental state examination score prediction.Therefore,it can be used as a reference for the clinical diagnosis of Alzheimer's disease,and can also help doctors and patients track disease progression in a timely manner.
文摘Purpose： To investigate the profiles of cognitive impairment through Montreal Cognitive Assessment （MoCA） and Mini-Mental State Examination （MMSE） in patients with chronic traumatic brain injury （TBI） or stroke and to evaluate the sensitivity of the two scales in patients with TBI. Methods： In this cohort study, a total of 230 patients were evaluated, including TBI group （n = 103） and stroke group （n - 127）. The cognitive functions of two groups were evaluated by designated specialists using MoCA （Beijing version） and MMSE （Chinese version）. Results： Compared with the patients with stroke, the patients with TBI received significantly lower score in orientation subtest and recall subtest in both tests. MoCA abnormal rates in the TBI group and stroke group were 94.17% and 86.61% respectively, while MMSE abnormal rates were 69.90% and 57.48%, respectively. In the TBI group, 87.10% patients with normal MMSE score had abnormal MoCA score and in the stroke group, about 70.37% patients with normal MMSE score had abnormal MoCA score. The diagnostic consistency of two scales in the TBI group and the stroke group were 72% and 69%, re.spectively. Conclusion： In our rehabilitation center, patients with TBI may have mare extensive and severe cognitive impairments than patients with stroke, prominently in orientation and recall domain. In screening post- TBI cognitive impairment, MoCA tends to be more sensitive than MIV[SE.
文摘目的研究快乐感知训练团体护理模式用于老年痴呆伴发抑郁情绪患者的价值。方法观察我院在2022年1月~2023年1月就诊的老年痴呆伴发抑郁情绪患者80例,按抽签法分为观察组40例及对照组40例。对照组采取常规护理,观察组在对照组的基础上进行快乐感知训练团体护理。比较两组心理状态,记录两组焦虑自评量表(Self-Rating Anxiety Scale,SAS)、抑郁自评量表(Self-Rating Dpression Scale,SDS)、简易精神状态评价量表(Mini-Mental State Examination,MMSE)、临床痴呆评定量表(Clinical Dementia Rating,CDR)、日常生活能力量表(Activity of Daily Living Scale,ADL)及健康状况调查简表(the MOS item short from health survey,SF-36)评分,收集患者家属满意度。结果干预后两组患者SAS、SDS评分较干预前显著下降,且观察组低于对照组(P<0.05);干预后两组MMSE、ADL、SF-36评分较干预前上升,CDR评分下降,观察组MMSE、ADL、SF-36高于对照组,CDR低于对照组(P<0.05);观察组患者家属满意度高于对照组(P<0.05)。结论快乐感知训练团体护理模式用于老年痴呆伴发抑郁情绪患者的临床价值高,能够有效缓解患者焦虑、抑郁情绪,适用于临床。
