Metallic biomaterials are increasingly being used in various medical applications due to their high strength,fracture resistance,good electrical conductivity,and biocompatibility.However,their practical applications h...Metallic biomaterials are increasingly being used in various medical applications due to their high strength,fracture resistance,good electrical conductivity,and biocompatibility.However,their practical applications have been largely limited due to poor surface performance.Laser microprocessing is an advanced method of enhancing the surface-related properties of biomaterials.This work demonstrates the capability of laser microprocessing for biomedical metallic materials including magnesium and titanium alloys,with potential applications in cell adhesion and liquid biopsy.We investigate laser-material interaction,microstructural evolution,and surface performance,and analyze cell behavior and the surface-enhanced Raman scattering(SERS)effect.Furthermore,we explore a theoretical study on the laser microprocessing of metallic alloys that shows interesting results with potential applications.The results show that cells exhibit good adhesion behavior at the surface of the laser-treated surface,with a preferential direction based on the textured structure.A significant SERS enhancement of 6×10^3 can be obtained at the laser-textured surface during Raman measurement.展开更多
采用聚焦连续波 CO2 激光束对 n型 In P基片进行局域加热 ,并利用专用的温度测量系统对 In P基片曝光区的温度分布及温度随时间的变化进行了测量 .结果表明 ,在基片初始温度为室温时 ,难以得到满足加工所要求的温度上升 .增大曝光区面...采用聚焦连续波 CO2 激光束对 n型 In P基片进行局域加热 ,并利用专用的温度测量系统对 In P基片曝光区的温度分布及温度随时间的变化进行了测量 .结果表明 ,在基片初始温度为室温时 ,难以得到满足加工所要求的温度上升 .增大曝光区面积和对基片预热可以使温度上升的幅度达到要求 ,但温度的稳定性较差 .采用研制的温度控制系统 。展开更多
基金the National Key R&D Program of China(2018YFB1107400)the National Key Basic Research Program of China(2015CB059900)+1 种基金the National Natural Science Foundation of China(51705013)the Beijing Natural Science Foundation(3162019 and J170002).
文摘Metallic biomaterials are increasingly being used in various medical applications due to their high strength,fracture resistance,good electrical conductivity,and biocompatibility.However,their practical applications have been largely limited due to poor surface performance.Laser microprocessing is an advanced method of enhancing the surface-related properties of biomaterials.This work demonstrates the capability of laser microprocessing for biomedical metallic materials including magnesium and titanium alloys,with potential applications in cell adhesion and liquid biopsy.We investigate laser-material interaction,microstructural evolution,and surface performance,and analyze cell behavior and the surface-enhanced Raman scattering(SERS)effect.Furthermore,we explore a theoretical study on the laser microprocessing of metallic alloys that shows interesting results with potential applications.The results show that cells exhibit good adhesion behavior at the surface of the laser-treated surface,with a preferential direction based on the textured structure.A significant SERS enhancement of 6×10^3 can be obtained at the laser-textured surface during Raman measurement.
