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Elastic response of doleritic sill to high temperatures,Sonhat Basin,India
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作者 Chinmay Sethi Bodhisatwa Hazra +4 位作者 Ali Soleimani Mehdi Ostadhassan Soumyajit Mukherjee Dripta Dutta Jai Krishna PandeyHide More 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第12期7503-7514,共12页
Understanding the thermo-mechanical behavior of various rock types is important in a wide range of geoscientific applications.In this study,the effects of elevated temperature treatments(250℃-750℃)on the elastic res... Understanding the thermo-mechanical behavior of various rock types is important in a wide range of geoscientific applications.In this study,the effects of elevated temperature treatments(250℃-750℃)on the elastic response(wave velocities and mechanical properties)of dolerite,retrieved from a borehole in the Sonhat Basin,India,were analyzed.The results showed that uniaxial compressive strength(UCS)increased by 15.4%at 250℃ compared to their room temperature(25℃)counterparts due to drying effects and inherent rock strengthening,but declined steadily at higher temperatures due to heat-induced microcracking and mineral transformations.Similarly,Young's modulus of the rock samples increased up to 250℃ and then decreased sharply above 450℃,aligning with the brittle-ductile transition temperature of 450℃.Petrographic and electron microscopy analyses of the samples revealed the development of intergranular and intragranular fractures at temperatures above 450℃,contributing to the observed mechanical weakening.Furthermore,ultrasonic wave velocities(P-and S-waves)exhibited significant reductions with increasing temperature,highlighting microstructural damage.These findings provide critical knowledge for designing underground geological engineering structures by identifying temperature thresholds and understanding mechanical degradation under thermal stress.The findings are particularly relevant for underground coal gasification(UCG)projects in the Sonhat Coalfield,where dolerite sills overlying coal seams may be exposed to significant heat.The identified threshold temperatures and trends in mechanical behaviour provide valuable insights for addressing structural stability challenges and mitigating environmental risks,such as surface subsidence. 展开更多
关键词 Uniaxial compressive strength Young’s modulus Microfractures
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Formation Mechanism of the High-quality Upper Paleozoic Natural Gas Reservoirs in the Ordos Basin 被引量:13
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作者 ZHAO Wenzhi WANG Zecheng CHEN Menjin ZHENG Hongju 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2005年第6期843-855,共13页
The upper Paleozoic natural gas reservoirs in the Ordos basin are generally characterized by a large gas-bearing area and low reserve abundance. On such a geological background, there still exist gas-enriched zones, w... The upper Paleozoic natural gas reservoirs in the Ordos basin are generally characterized by a large gas-bearing area and low reserve abundance. On such a geological background, there still exist gas-enriched zones, with relatively high outputs, high reserve abundance and stably distributed gas layers. The gas-enriched layers with relatively high permeability (the lower limit permeability is 0.5×10^-3μm^2) are key factors for the enrichment and high output of natural gas. Based on core observation, analytic results of inclusions, and a great deal of drilling data, we proposed the following four mechanisms for the formation of high-quality reservoirs: (1) in the source area the parent rocks are mainly metamorphic rocks and granites, which are favorable to keeping primary porosity; (2) under the condition of low A/S (accommodation/sediment supply) ratios, sandstone complex formed due to multistage fluvial stacking and filling are coarse in grain size with a high degree of sorting, low content of mud and good physical properties; (3) early-stage recharge of hydrocarbons restricted compaction and cementation, and thus are favorable to preservation of primary pores; (4) microfractures caused by the activity of basement faults during the Yanshan Movement stage can not only improve the permeability of tight sandstones, but also afford vertical pathways for hydrocarbon gas migration. 展开更多
关键词 lithology of parent rock A/S ratio recharge of hydrocarbons microfractures multistage fluvial complex upper Paleozoic Ordos Basin
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Stability analysis of surrounding rock mass in underground powerhouse considering damage effect of microfractures 被引量:3
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作者 Peiwei Xiao Haoyu Mao +3 位作者 Bo Qian Biao Li Xingguo Yang Nuwen Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2022年第4期1115-1130,共16页
A high-precision microseismic(MS)monitoring system was built to monitor surrounding rock microfractures in the underground powerhouse on the left bank of Shuangjiangkou Hydropower Station.The surrounding rock damage a... A high-precision microseismic(MS)monitoring system was built to monitor surrounding rock microfractures in the underground powerhouse on the left bank of Shuangjiangkou Hydropower Station.The surrounding rock damage area with spatiotemporal clustering of MS activities was studied for qualitative analysis of the damage mechanism of surrounding rock microfractures,based on the source parameters of MS events.The surrounding rock microfracture scale characterized by the source radius of MS events was considered to establish the constitutive relation.MS information was imported into the model for numerical analysis using fast Lagrangian analysis of continuain 3 dimensions(FLAC^(3D)).The results indicated that the numerical simulation results considering MS damage can better reflect the actual situation of the field.The surrounding rock microfractures mainly showed mixed failure characteristics.Shear failures appeared in localized areas while the fracture scale of sections from K0e33 m to K0e15 m on the vault was large.The deformation increment caused by microfracture damage in the shallow surrounding rock of the top arch accounted for 10%e13%,and the stress decrement in the surrounding rock caused by microfracture damage accounted for about 10%. 展开更多
关键词 Underground powerhouse Microseismic(MS)monitoring Numerical modeling Microfracture damage Constitutive relation
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Treatment for cartilage injuries of the knee with a new treatment algorithm 被引量:3
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作者 Ahmet ?zmeri? Kadir Bahad?r Alemdaro?lu Nevres Hürriyet Aydo?an 《World Journal of Orthopedics》 2014年第5期677-684,共8页
Treatment of articular cartilage injuries to the knee remains a considerable challenge today. Current procedures succeed in providing relief of symptoms, however damaged articular tissue is not replaced with new tissu... Treatment of articular cartilage injuries to the knee remains a considerable challenge today. Current procedures succeed in providing relief of symptoms, however damaged articular tissue is not replaced with new tissue of the same biomechanical properties and long-term durability as normal hyaline cartilage. Despite many arthroscopic procedures that often manage to achieve these goals, results are far from perfect and there is no agreement on which of these procedures are appropriate, particularly when full-thickness chondral defects are considered.Therefore, the search for biological solution in long-term functional healing and increasing the quality of wounded cartilage has been continuing. For achieving this goal and apply in wide defects, scaffolds are developed.The rationale of using a scaffold is to create an environment with biodegradable polymers for the in vitro growth of living cells and their subsequent implantation into the lesion area. Previously a few numbers of surgical treatment algorithm was described in reports, however none of them contained one-step or two –steps scaffolds. The ultimate aim of this article was to review various arthroscopic treatment options for different stage lesions and develop a new treatment algorithm which included the scaffolds. 展开更多
关键词 CHONDRAL lesion MICROFRACTURE OSTEOCHONDRAL transplantation AUTOLOGOUS CHONDROCYTE implantation Scaffolds
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Microfracture Characterization in Sandstone Reservoirs:A Case Study from the Upper Triassic of Syria's Euphrates Graben 被引量:2
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作者 Ibrahem Yousef Vladimir Morozov +1 位作者 Vladislav Sudakov Ilyas Idrisov 《Journal of Earth Science》 SCIE CAS CSCD 2022年第4期901-915,共15页
The Euphrates Graben is located in eastern Syria.The Upper Triassic Mulussa F Formation sandstones serve as the primary reservoir intervals in the majority of the graben fields.The study’s findings were based on core... The Euphrates Graben is located in eastern Syria.The Upper Triassic Mulussa F Formation sandstones serve as the primary reservoir intervals in the majority of the graben fields.The study’s findings were based on core studies:petrographic examination of thin sections,scanning electron microscope(SEM),imaging of backscatter scanning electron microscope(BSE),X-ray microprobe examinations,and carbon-oxygen stable isotope analysis of microfracture-filling cements.Three of the most common types of microfracture found in the investigated sandstones are intragranular or intracrystalline microfractures,grain boundary or grain-edge microfractures,and transgranular(crossing grains)microfractures.Sandstone microfractures that are open and free of secondary mineralization improve sandstone storage and permeability.However,microfractures that are cemented and filled with secondary mineralization reduce storage and permeability.Common siderite and pyrite cements were identified within the microfractures and the nearby sandstone matrix.Larger anhedral or euhedral siderites are thought to form during shallow burial diagenesis,whereas poikilotopic siderites are thought to form during deep burial diagenesis.Poikilotopic pyrite is believed to be a diagenetic cement,which is attributed to the reduction of iron oxides present in the sediments in the presence of hydrocarbons.Microfractures reflect tectonic,overpressure,and diagenetic origins.Microfractures of tectonic origin are associated with folding and thrust activities over the Euphrates Graben area,and they were formed at the beginning of the Upper Triassic with siderite and pyrite cement equilibration temperatures of approximately 100–105℃,and they continued forming from the middle to the end of the Upper Triassic with cement equilibration temperatures of approximately 90–100℃in conjunction with the first phase of the Euphrates Graben.Microfractures related to diagenetic and overpressure processes are tension microfractures and were formed in compression settings during the Upper Triassic. 展开更多
关键词 MICROFRACTURE SANDSTONE Upper Triassic Mulussa F Euphrates Graben SYRIA
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Anisotropic Variation Law of Rock Permeability with the Burial Depth of Limestone 被引量:2
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作者 TIAN Kaiming, WAN Li and TIAN Jiping Department of Water Resources and Environmental Science, China University of Geosciences,27 Xueyuan Road, Beijing 100083, Department of Computer Sciences, Guangzhou University, Guangzhou, Guangdong 510091 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2003年第1期125-128,共4页
Permeability tensors of both macrofracture and microfracture Systems weremeasured progressively along the depth of limestone formations at severed sites. It was found thatthe principal permeability values K_x, K_y and... Permeability tensors of both macrofracture and microfracture Systems weremeasured progressively along the depth of limestone formations at severed sites. It was found thatthe principal permeability values K_x, K_y and K_z in these permeability tensors all decreasesimultaneously and logarithmically with depth. However, the limestone aquifers are composed of anupper region where the larger permeability ellipsoid is upright or prolate and characterized byK_z>K_x and K_z>K_y, a transitional zone, and a lower zone whose smaller permeability ellipsoid ishorizontal or oblate and characterized by K_z>K_x and K_z>K_y. The inversion of the permeabilityellipsoids in direction indicates that the anisotropy of rock permeability with the depth oflimestone formations has evidently changed. The anisotropic variation law of permeability tensors ina macrofracture system displays a similar pattern with that in a microfracture system. It is nextto impossible to examine the rock permeability tensor of the aquifer just by measuring the hydraulicparameters of macrofracture system directly, unless the limestone aquifer is exposed on or near theearth's surface. Therefore, the permeability tensors of a macrofracture system at any depth may beindirectly and roughly determined from the gaugeable permeability tensors of the microfracturesystem by conversion. This anisotropic variation law of rock permeability with depth is of greatsignificance in the study of three-dimensional fracture water flow the huge carbonate formations andin the research on the conditions of karst development and karst distribution. 展开更多
关键词 macrofracture system microfracture system permeability tensor permeability ellipsoid
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Effect of thermal maturation and organic matter content on oil shale fracturing 被引量:2
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作者 Fatemeh Saberi Mahboubeh Hosseini‑Barzi 《International Journal of Coal Science & Technology》 EI CAS CSCD 2024年第2期16-34,共19页
The Pabdeh Formation represents organic matter enrichment in some oil fields,which can be considered a source rock.This study is based on the Rock–Eval,Iatroscan,and electron microscopy imaging results before and aft... The Pabdeh Formation represents organic matter enrichment in some oil fields,which can be considered a source rock.This study is based on the Rock–Eval,Iatroscan,and electron microscopy imaging results before and after heating the samples.We discovered this immature shale that undergoes burial and diagenesis,in which organic matter is converted into hydro-carbons.Primary migration is the process that transports hydrocarbons in the source rock.We investigated this phenomenon by developing a model that simulates hydrocarbon generation and fluid pressure during kerogen-to-hydrocarbon conversion.Microfractures initially formed at the tip/edge of kerogen and were filled with hydrocarbons,but as catagenesis progressed,the pressure caused by the volume increase of kerogen decreased due to hydrocarbon release.The transformation of solid kerogen into low-density bitumen/oil increased the pressure,leading to the development of damage zones in the source rock.The Pabdeh Formation’s small porethroats hindered effective expulsion,causing an increase in pore fluid pressure inside the initial microfractures.The stress accumulated due to hydrocarbon production,reaching the rock’s fracture strength,further contributed to damage zone development.During the expansion process,microfractures preferentially grew in low-strength pathways such as lithology changes,laminae boundaries,and pre-existing microfractures.When the porous pressure created by each kerogen overlapped,individual microfractures interconnected,forming a network of microfractures within the source rock.This research sheds light on the complex interplay between temperature,hydrocarbon generation,and the development of expulsion fractures in the Pabdeh Formation,providing valuable insights for understanding and optimizing hydrocarbon extraction in similar geological settings. 展开更多
关键词 Oil shale MICROFRACTURE Hydrocarbon generation Organic matter Thermal maturation Primary migration
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Enhanced microfracture techniques in cartilage knee surgery: Fact or fiction? 被引量:3
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作者 Stefan Bark Tomasz Piontek +3 位作者 Peter Behrens Sabiah Mkalaluh Deike Varoga Justus Gille 《World Journal of Orthopedics》 2014年第4期444-449,共6页
The limited intrinsic healing potential of human articular cartilage is a well-known problem in orthopedic surgery. Thus a variety of surgical techniques have been developed to reduce joint pain, improve joint functio... The limited intrinsic healing potential of human articular cartilage is a well-known problem in orthopedic surgery. Thus a variety of surgical techniques have been developed to reduce joint pain, improve joint function and delay the onset of osteoarthritis. Microfractures as a bone marrow stimulation technique present the most common applied articular cartilage repair procedure today. Unfortunately the deficiencies of fibrocartilaginous repair tissue inevitably lead to breakdown under normal joint loading and clinical results deteriorate with time. To overcome the shortcomings of microfracture, an enhanced microfracture technique was developed with an additional collagen Ⅰ/Ⅲ membrane(Autologous, Matrix-Induced Chondrogenesis, AMIC). This article reviews the pre-clinical rationale of microfractures and AMIC, presents clinical studies and shows the advantages and disadvantages of these widely usedtechniques. PubM ed and the Cochrane database were searched to identify relevant studies. We used a comprehensive search strategy with no date or language restrictions to locate studies that examined the AMIC technique and microfracture. Search keywords included cartilage, microfracture, AMIC, knee, ChondroGide. Besides this, we included our own experiences and study authors were contacted if more and non published data were needed. Both cartilage repair techniques represent an effective and safe method of treating full-thickness chondral defects of the knee in selected cases. While results after microfracture deteriorate with time, mid-term results after AMIC seem to be enduring. Randomized studies with long-term followup are needed whether the grafted area will maintain functional improvement and structural integrity over time. 展开更多
关键词 CARTILAGE MICROFRACTURE Autologous Matrix-Induced Chondrogenesis Knee Chondro-Gide
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Identification and characterization of microfractures in carbonate samples 被引量:2
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作者 PERMADI Pudji MARHAENDRAJANA Taufan +1 位作者 NANDYA Sesilia IDEA Kharisma 《Petroleum Exploration and Development》 CSCD 2022年第2期415-427,共13页
Based on the rock typing method of pore geometry and structure(PGS), rock samples from carbonate reservoir A and carbonate reservoir B were classified using data of routine and special core analysis and thin section i... Based on the rock typing method of pore geometry and structure(PGS), rock samples from carbonate reservoir A and carbonate reservoir B were classified using data of routine and special core analysis and thin section images, and microfractures in the carbonate reservoir samples were identified and characterized. Establishment of rock types demonstrates that microfractures have developed in all rock types in carbonate reservoir A, but only partially in certain rock types in carbonate reservoir B with porosity of 1%–11%, less vuggy, and hardness of medium hard to hard. The cut-off porosity was determined for each type of rock to distinguish samples with and without conductive microfractures. The impact of conductive microfractures on improving permeability was analyzed. On the basis of relationship of permeability and original initial water saturation, the permeability equation was derived by certain special core analysis data with conductive microfractures selected by PGS equation, and the permeability of samples with conductive microfractures has been successfully predicted. 展开更多
关键词 carbonate rock MICROFRACTURE rock classification PERMEABILITY
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Effect of fracture fluid flowback on shale microfractures using CT scanning 被引量:2
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作者 Jiale He Zhihong Zhao +6 位作者 Yiran Geng Yuping Chen Jianchun Guo Cong Lu Shouyi Wang Xueliang Han Jun Zhang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第2期426-436,共11页
The field data of shale fracturing demonstrate that the flowback performance of fracturing fluid is different from that of conventional reservoirs,where the flowback rate of shale fracturing fluid is lower than that o... The field data of shale fracturing demonstrate that the flowback performance of fracturing fluid is different from that of conventional reservoirs,where the flowback rate of shale fracturing fluid is lower than that of conventional reservoirs.At the early stage of flowback,there is no single-phase flow of the liquid phase in shale,but rather a gas-water two-phase flow,such that the single-phase flow model for tight oil and gas reservoirs is not applicable.In this study,pores and microfractures are extracted based on the experimental results of computed tomography(CT)scanning,and a spatial model of microfractures is established.Then,the influence of rough microfracture surfaces on the flow is corrected using the modified cubic law,which was modified by introducing the average deviation of the microfracture height as a roughness factor to consider the influence of microfracture surface roughness.The flow in the fracture network is simulated using the modified cubic law and the lattice Boltzmann method(LBM).The results obtained demonstrate that most of the fracturing fluid is retained in the shale microfractures,which explains the low fracturing fluid flowback rate in shale hydraulic fracturing. 展开更多
关键词 SHALE Flowback of fracturing fluid MICROFRACTURE Lattice Boltzmann method(LBM)
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Pore and fracture characteristics of Cretaceous tight reservoir and its control effect on hydrocarbon accumulation in the Liuhe Basin 被引量:1
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作者 Wen-Hao Li Er-Qiang Yang +1 位作者 Min Wang Yan-Ran Huang 《Petroleum Science》 SCIE CAS CSCD 2022年第5期1939-1949,共11页
Tight oil and gas in the Cretaceous has been found in the Liuhe Basin,but the rules of tight reservoir and oil and gas accumulation are not clear.This paper discusses the developmental characteristics and evolution la... Tight oil and gas in the Cretaceous has been found in the Liuhe Basin,but the rules of tight reservoir and oil and gas accumulation are not clear.This paper discusses the developmental characteristics and evolution law of pores and fractures in the Cretaceous tight reservoir in the Liuhe Basin,and reveals its controlling effect on tight oil and gas accumulation.The results show that intercrystalline pores,intergranular pores and dissolution pores are scattered and only developed in shallow tight reservoirs,while microfractures are developed in both shallow and deep layers,which are the main type of reservoir space in the study area.The results of mercury intrusion porosimetry and nitrogen gas adsorption show that with the increase of depth,the proportion of macropores(microcracks)increases,while the proportion of micropores decreases.There are two stages of microfractures developed in the study area,corresponding to the initial fault depression stage from late Jurassic to early late Cretaceous and compressional uplift at the end of late Cretaceous.According to the principle of“inversion and back-stripping method”,combined with the data of optical microscopy and inclusions,the time of each key diagenesis and its contribution to porosity are revealed,and the porosity evolution history of reservoirs in different diagenetic stages is quantitatively restored.The porosity reduction rate of compaction can reach more than 80%,which is the main reason for reservoir densification.The relationship between pore evolution history and oil and gas accumulation history reveals that during the oil and gas filling period of the Xiahuapidianzi Formation(90-85 Ma),the reservoir porosity is only 1.15%,but the development of microfractures in the first stage of the reservoir is conducive to oil and gas accumulation. 展开更多
关键词 Tight reservoir Microscopic pore structure MICROFRACTURE Porosity evolution Hydrocarbon accumulation the liuhe Basin
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A discontinuum-based model to simulate compressive and tensile failure in sedimentary rock 被引量:1
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作者 T.Kazerani 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2013年第5期378-388,共11页
The study presented in this paper discusses a discontinuum-based model for investigating strength and failure in sedimentary rocks.The model has been implemented by UDEC to incorporate an innovative orthotropic cohesi... The study presented in this paper discusses a discontinuum-based model for investigating strength and failure in sedimentary rocks.The model has been implemented by UDEC to incorporate an innovative orthotropic cohesive constitutive law for contact.To reach this purpose,a user-defned model has been established by creating dynamic link libraries(DLLs)and attaching them into the code.The model reproduces rock material by a dense collection of irregular-sized deformable particles interacting at their cohesive boundaries which are viewed as flexible contacts whose stress-displacement law is assumed to control the fracture and the fragmentation behaviours of the material.The model has been applied to a sandstone.The individual and interactional effects of the microstructural parameters on the material compressive and tensile failure responses have been examined.In addition,the paper presents a new methodical calibration procedure to ft the modelling microparameters.It is shown that the model can successfully reproduce the rock mechanical behaviour quantitatively and qualitatively.The study also shows how discontinuum-based modelling can be used to characterize the relation between the microstructural parameters and the macro-scale properties of a material. 展开更多
关键词 Rock microstructure Microparameter MICROFRACTURE Orthotropic cohesive interface Discrete element method
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Quantitative characterization of tight gas sandstone reservoirs using seismic data via an integrated rock-physics-based framework 被引量:1
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作者 Zhi-Qi Guo Xiao-Ying Qin Cai Liu 《Petroleum Science》 SCIE EI CAS CSCD 2023年第6期3428-3440,共13页
Seismic characterizing of tight gas sandstone (TGS) reservoirs is essential for identifying promising gas-bearing regions. However, exploring the petrophysical significance of seismic-inverted elastic properties is ch... Seismic characterizing of tight gas sandstone (TGS) reservoirs is essential for identifying promising gas-bearing regions. However, exploring the petrophysical significance of seismic-inverted elastic properties is challenging due to the complex microstructures in TGSs. Meanwhile, interbedded structures of sandstone and mudstone intensify the difficulty in accurately extracting the crucial tight sandstone properties. An integrated rock-physics-based framework is proposed to estimate the reservoir quality of TGSs from seismic data. TGSs with complex pore structures are modeled using the double-porosity model, providing a practical tool to compute rock physics templates for reservoir parameter estimation. The VP/VS ratio is utilized to predict the cumulative thickness of the TGS reservoirs within the target range via the threshold value evaluated from wireline logs for lithology discrimination. This approach also facilitates better capturing the elastic properties of the TGSs for quantitative seismic interpretation. Total porosity is estimated from P-wave impedance using the correlation obtained based on wireline log analysis. After that, the three-dimensional rock-physics templates integrated with the estimated total porosity are constructed to interpret microfracture porosity and gas saturation from velocity ratio and bulk modulus. The integrated framework can optimally estimate the parameters dominating the reservoir quality. The results of the indicator proposed based on the obtained parameters are in good agreement with the gas productions and can be utilized to predict promising TGS reservoirs. Moreover, the results suggest that considering microfracture porosity allows a more accurate prediction of high-quality reservoirs, further validating the applicability of the proposed method in the studied region. 展开更多
关键词 Tight gas sandstone reservoirs Quantitative reservoir characterization Rock-physics-based framework Microfracture porosity Rock physics template
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DEFORMATION AND MICROFRACTURE OF GRANULAR BAINITE 被引量:1
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作者 CHEN Huangpu Xi’an Jiaotong University,Xi’an,China Lecturer,The Research Institute for Strength of Metals,Xi’an Jiaotong University,Xi’an 710049,China 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 1992年第6期432-435,共4页
Relationship among deformation history,fracture process and stress distribution of granular bainite has been investigated.The main process of fracture of granular bainite is the forma- tion.growth and coalescence of t... Relationship among deformation history,fracture process and stress distribution of granular bainite has been investigated.The main process of fracture of granular bainite is the forma- tion.growth and coalescence of the microvoids.Even though the microcracks have formed at the earlier stage of deformation,they are not fateful for fracture because in the successive deformation stage the microcracks change their orientation toward the tensile axis.The strain hardening rate of granular bainite has a minimal value during the deformation process. Before and after the strain of the minimal value,the material shows different stress distribu- tion and microfracture mechanism. 展开更多
关键词 granular bainite MICROFRACTURE strain hardening rate
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Repair of articular cartilage defects in minipigs by microfracture surgery and BMSCs transplantation 被引量:1
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作者 左镇华 杨柳 +1 位作者 段小军 郭林 《Journal of Medical Colleges of PLA(China)》 CAS 2007年第5期288-292,共5页
Objective:To investigate the feasibility of minimal invasive repair of cartilage defect by arthroscope-aided microfracture surgery and autologous transplantation of mesenchymal stem cells. Methods: Bone marrow of mini... Objective:To investigate the feasibility of minimal invasive repair of cartilage defect by arthroscope-aided microfracture surgery and autologous transplantation of mesenchymal stem cells. Methods: Bone marrow of minipigs was taken out and the bone marrow derived mesenchymal stem cells (BMSCs) were isolated and cultured to passage 3. Then 6 minipigs were randomly divided into 2 groups with 6 knees in each group. After the articular cartilage defect was induced in each knee, the left defect received microfracture surgery and was injected with 2.5 ml BMSCs cells at a concentration of 3×107 cells/ml into the articular cavity; while right knee got single microfracture or served as blank control group. The animals were killed at 8 or 16 weeks, and the repair tissue was histologically and immunohistochemically examined for the presence of type Ⅱ collagen and glycosaminoglycans (GAGs) at 8 and 16 weeks. Results: Eight weeks after the surgery, the overlying articular surface of the cartilage defect showed normal color and integrated to adjacent cartilage. And 16 weeks after surgery, hyaline cartilage was observed at the repairing tissues and immunostaining indicated the diffuse presence of this type Ⅱ collagen and GAGs throughout the repair cartilage in the treated defects. Single microfracture group had the repairing of fibrocartilage, while during the treatment, the defects of blank group were covered with fewer fiber tissues, and no blood capillary growth or any immunological rejection was observed. Conclusion: Microfracture technique and BMSCs transplantation to repair cartilage defect is characterized with minimal invasion and easy operation, and it will greatly promote the regeneration repair of articular cartilage defect. 展开更多
关键词 cartilage defect MICROFRACTURE bone marrow derived mesenchymal stem cells cartilage regeneration
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Action mechanisms of abnormal fluid pressure on physical properties of deep reservoirs: A case study on Jurassic Toutunhe Formation in the southern margin of Junggar Basin, NW China 被引量:1
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作者 GAO Zhiyong CUI Jinggang +3 位作者 FAN Xiaorong FENG Jiarui SHI Yuxin LUO Zhong 《Petroleum Exploration and Development》 SCIE 2023年第6期1398-1410,共13页
Considering the action mechanisms of overpressure on physical changes in skeleton particles of deep reservoir rocks and the differences in physical changes of skeleton particles under overpressure and hydrostatic pres... Considering the action mechanisms of overpressure on physical changes in skeleton particles of deep reservoir rocks and the differences in physical changes of skeleton particles under overpressure and hydrostatic pressure, the sandstone of the Jurassic Toutunhe Formation in the southern margin of Junggar Basin was taken as an example for physical modeling experiment to analyze the action mechanisms of overpressure on the physical properties of deep reservoirs. (1) In the simulated ultra-deep layer with a burial depth of 6000-8000 m, the mechanical compaction under overpressure reduces the remaining primary pores by about a half that under hydrostatic pressure. Overpressure can effectively suppress the mechanical compaction to allow the preservation of intergranular primary pores. (2) The linear contact length ratio under overpressure is always smaller than the linear contact length ratio under hydrostatic pressure at the same depth. In deep reservoirs, the difference between the mechanical compaction degree under overpressure and hydrostatic pressure shows a decreasing trend, the effect of abnormally high pressure to resist the increase of effective stress is weakened, and the degree of mechanical compaction is gradually close to that under hydrostatic pressure. (3) The microfractures in skeleton particles of deep reservoirs under overpressure are thin and long, while the microfractures in skeleton particles of deep reservoirs under hydrostatic pressure are short and wide. This difference is attributed to the probable presence of tension fractures in the rocks containing abnormally high pressure fluid. (4) The microfractures in skeleton particles under overpressure were mainly formed later than that under hydrostatic pressure, and the development degree and length of microfractures both extend deeper. (5) The development stages of microfractures under overpressure are mainly controlled by the development stages of abnormally high pressure and the magnitude of effective stress acting on the skeleton particles. Moreover, the development stages of microfractures in skeleton particles are more than those under hydrostatic pressure in deep reservoir. The multi-stage abnormally high pressure plays an important role in improving the physical properties of deep reservoirs. 展开更多
关键词 abnormally high fluid pressure deep reservoir MICROFRACTURE physical simulation of diagenesis Jurassic Toutunhe Formation southern margin of Junggar Basin
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Quantitative characterization of irregular microfracture network and its effect on the permeability of porous media 被引量:1
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作者 LI Tao LI Qian +4 位作者 HU Yong PENG Xian FENG Xi ZHU Zhanmei ZHAO Zihan 《Petroleum Exploration and Development》 CSCD 2021年第2期430-441,共12页
Based on the comprehensive understanding on microfractures and matrix pores in reservoir rocks,numerical algorithms are used to construct fractured porous media and fracture-pore media models.Connectivity coefficient ... Based on the comprehensive understanding on microfractures and matrix pores in reservoir rocks,numerical algorithms are used to construct fractured porous media and fracture-pore media models.Connectivity coefficient and strike factor are introduced into the models to quantitatively characterize the connectivity and strike of fracture network,respectively.The influences of fracture aperture,fracture strike and fracture connectivity on the permeability of porous media are studied by using multi-relaxation-time lattice Boltzmann model to simulate fluid flow in them.The greater the strike factor and the smaller the tortuosity of the fractured porous media,the greater the permeability of the fractured porous media.The greater the connectivity coefficient of the fracture network is,the greater the permeability of the fracture-pore media is,and the more likely dominant channel effect occurs.The fracture network connectivity has stronger influence on seepage ability of fracture-pore media than fracture aperture and fracture strike.The tortuosity and strike factor of fracture network in fractured porous media are in polynomial relation,while the permeability and fracture network connectivity coefficient of the fracture-pore media meet an exponential relation. 展开更多
关键词 MICROFRACTURE fracture network connectivity fracture network strike lattice Boltzmann model PERMEABILITY
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EFFECTS OF ROCK BEHAVIOR AND STRESS CONDITION ON FIELD STRESS DETERMINATION 被引量:1
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作者 D. H. (Steve) Zou (Department of Mining and Metallurgical Engineering,Technical University of Nova Scotia, Canada) 《Journal of China University of Mining and Technology》 1995年第1期23-33,共11页
Non-consistency of stress results is of ten observed during field measurements. In some cases, even the rneasurernents are made at the same location in a massive rockrnass, the results can vary widely. In order to sol... Non-consistency of stress results is of ten observed during field measurements. In some cases, even the rneasurernents are made at the same location in a massive rockrnass, the results can vary widely. In order to solve the problem, extensive research has been carried out to study the major factors wh1ch rnay affect stress deterrnlnation. They include the rock behaviour and the stress state. For rocks showing non-isotropic behaviour, the values of Young’s modulus and Poisson ratio vary with the orientation of loading and measurement. Stress condition in the rock affects the rock behaviour. Furtherrnore, the loading condition on rock samples durlng laboratory tests is different from in the field and therefore the determined e1astic constants may not represent the field condi tion. In general , the Young’s modulus may depend on the orientation, the loading path, the stress magnitude and the stress ratio. This paper examines in detail the effects of those factors, especially for rocks showing transversely isotropic behaviour. It is found that the discrepancy of stress results from field measurernents in this type of rock is mainly due to over simplification of the rock behavior and inadequate use of elastic constants of the rock during stress calculation. A case study is given,which indicates the significance of these factors and demonstrates the proper procedure for stress calculation from measurements. 展开更多
关键词 in-situ stress overcoring transverse isotropy microfractures Young 's modulus stress state
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Effects of Early Weightbearing on Microfracture Treatment of Osteochondral Lesions of Talus with Subchondral Bone Defects
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作者 Min WEI Yu WEI Yang LIU 《Current Medical Science》 SCIE CAS 2019年第1期88-93,共6页
When subchondral bone defects are present in osteochondral lesions of the talus(OCLT),it is inconclusive whether to allow early weightbearing after microfracture treatment because of the lack of effective support of t... When subchondral bone defects are present in osteochondral lesions of the talus(OCLT),it is inconclusive whether to allow early weightbearing after microfracture treatment because of the lack of effective support of the newly-formed fibrocartilage.After performing arthroscopic debridement and microfracture treatment on OCLT patients with subchondral bone defects,we allowed patients to have an early postoperative weightbearing exercise to observe their clinical outcome.Forty-two OCLT patients with subchondral bone defects were analyzed.Patients were randomly divided into two groups with 21 patients in each group.After arthroscopic debridement and microfracture treatment,group A was allowed to have early partial weightbearing while weightbearing was delayed in group B.Visual analogue scale(VAS)was used to evaluate joint pain before and after surgery.American Orthopaedic Foot and Ankle Society(AOFAS)anklc-hindfoot score was used to evaluate joint function.Tegner activity scale was used to assess patient's exercise level.The AOFAS ankle-hindfoot score in group A increased from 54.4 to 87.6,and that in group B increased from 54.9 to 87.3.The VAS score in group A decreased from 6.5 to 2.2,and that in group B decreased from 6.4 to 2.3.The Tegner activity scale increased from 2.6 to 4.4 in group A,and that in group B increased from 2.6 to 3.9.There was significant difference in the Tegner activity scale between group A and group B(P<0.05).It was suggested that when performing microfracture treatmenf on OCLT patients with subchondral bone defects,early postoperative weightbearing may achieve similar clinical outcomes as delayed weightbearing,and patients may be better able to return to sports. 展开更多
关键词 OSTEOCHONDRAL LESIONS of the TALUS subchondral BONE ARTHROSCOPIC MICROFRACTURE weightbearing time
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Imaging dynamic water invasion behavior in microfractures based on microfluidics
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作者 ZHANG Ji-cheng CHEN Shao-jie +3 位作者 JI Song-tao FENG Fan ALEKSEY A.Khoreshok ZAKI M.Mohammed 《Journal of Central South University》 SCIE EI CAS CSCD 2022年第12期3986-4001,共16页
Fluid invasion through fractures is frequently observed in subsurface engineering. To elucidate the microkinetic behavior of fracture fluids, the microfracture structure of coal from the Surat Basin was reconstructed ... Fluid invasion through fractures is frequently observed in subsurface engineering. To elucidate the microkinetic behavior of fracture fluids, the microfracture structure of coal from the Surat Basin was reconstructed using a 3D morphometric system and stitching algorithm, then the transparent models characterizing the fracture structure were produced using microfluidics, and water invasion in the microfracture model was measured via visualization experiments under various conditions. High flow rate facilitated the invasion of the water phase into the closed channel, improving the efficiency of water invasion in the neutral wetting system. Wettability reversal changed the dominant channel for water invasion in the hydrophobic system. The invasion efficiency in closed and small aperture bypass channels was low.The reduction of effective seepage channels led to the fastest breakthrough time. Higher surface tension and interfacial curvature promoted the hysteresis effect. The reduction of effective seepage channels led to the fastest breakthrough time. The larger surface tension and interfacial curvature make the hysteresis effect more significant. These results will enable a better understanding of the rock-gas-liquid multiphase interaction mechanisms under unsaturated conditions of rocks. 展开更多
关键词 MICROFRACTURE visualized models MICROFLUIDICS phase distribution capillary hysteresis
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