The tumor microenvironment plays a key role in malignant tumor progression.As a place where tumor cells survive,the tumor microenvironment contains not only tumor cells themselves but also biochemical and biophysical ...The tumor microenvironment plays a key role in malignant tumor progression.As a place where tumor cells survive,the tumor microenvironment contains not only tumor cells themselves but also biochemical and biophysical elements.Tumor cells can change the microenvironment,which in turn affects the survival and development of tumor cells.Tumor malignancy is a highly regulated pathological process following a series of complex cellular-biological events called invasion–metastasis cascades.In this correspondence,we intend to provide a comprehensive background on the tumor environment to inspire further innovations in relevant research areas in the future.展开更多
基金supported,in part or in whole,by the National Natural Science Foundation of China(11772088,31700811,11802056,31800780,and 81671821)the Research Program of Sichuan Science and Technology(2017JY0019,2017JY0217,2019YJ0183,and 2019YJ0184)+1 种基金the China Postdoctoral Science Foundation(2017JY0217,2018M640904,and 2019T120831)the Fundamental Research Funds for the Central Universities(ZYGX2016Z001).
文摘The tumor microenvironment plays a key role in malignant tumor progression.As a place where tumor cells survive,the tumor microenvironment contains not only tumor cells themselves but also biochemical and biophysical elements.Tumor cells can change the microenvironment,which in turn affects the survival and development of tumor cells.Tumor malignancy is a highly regulated pathological process following a series of complex cellular-biological events called invasion–metastasis cascades.In this correspondence,we intend to provide a comprehensive background on the tumor environment to inspire further innovations in relevant research areas in the future.
