The intestinal microbiome,which is a key factor in the maintenance of host gut homeostasis,enhances intestinal mucosal barrier function and immune tolerance(Rooks and Garrett,2016;Skelly et al.,2019).However,the speci...The intestinal microbiome,which is a key factor in the maintenance of host gut homeostasis,enhances intestinal mucosal barrier function and immune tolerance(Rooks and Garrett,2016;Skelly et al.,2019).However,the specific immunomodulatory functions of microbiota-derived metabolites in mucosal inflammatory responses remain largely unknown.展开更多
基金supported by the National Natural Science Foundation of China(Nos.323B200243,32172864,and U21A20261)the National Key Research and Development Plan of China(No.2022YFD1800804).
文摘The intestinal microbiome,which is a key factor in the maintenance of host gut homeostasis,enhances intestinal mucosal barrier function and immune tolerance(Rooks and Garrett,2016;Skelly et al.,2019).However,the specific immunomodulatory functions of microbiota-derived metabolites in mucosal inflammatory responses remain largely unknown.
