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Research progress and application of carbon sequestration in industrial flue gas by microalgae: A review 被引量:3
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作者 Rui Wang Xue Wang Tingyu Zhu 《Journal of Environmental Sciences》 2025年第6期14-28,共15页
Global warming caused by the emission of CO_(2) in industrial flue gas has attractedmore and more attention.Therefore,to fix CO_(2) with high efficiency and environmentally friendly had become the hot research field.C... Global warming caused by the emission of CO_(2) in industrial flue gas has attractedmore and more attention.Therefore,to fix CO_(2) with high efficiency and environmentally friendly had become the hot research field.Compared with the traditional coal-fired power plant flue gas emission reduction technology,carbon fixation and emission reduction by microalgae is considered as a promising technology due to the advantages of simple process equipment,convenient operation and environmental protection.When the flue gas is treated by microalgae carbon fixation and emission reduction technology,microalgae cells can fix CO_(2) in the flue gas through photosynthesis,and simultaneously absorb NO_(x) and SO_(x) as nitrogen and sulfur sources required for growth.Meanwhile,they can also absorb mercury,selenium,arsenic,cadmium,lead and other heavy metal ions in the flue gas to obtain microalgae biomass.The obtained microalgae biomass can be further transformed into high valueadded products,which has broad development prospects.This paper reviews the mechanisms and pathways of CO_(2) sequestration,the mechanism and impacts of microalgal emission reduction of flue gas pollutants,and the applications of carbon sequestration in industrial flue gas by microalgae.Finally,this paper provides some guidelines and prospects for the research and application of green emission reduction technology for industrial flue gas. 展开更多
关键词 microalgae Bio-mitigation Flue gas Carbon sequestration Carbon emission reduction Photosynthetic carbon fixation
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Biomass Production of Microalgae Scenedesmus in a Raceway and Tubular Photobioreactor
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作者 José F.Reyes Paulina J.Vielma +1 位作者 Wilson D.Esquivel Johannes P.de Bruijn 《Journal of Environmental Science and Engineering(B)》 2025年第6期255-264,共10页
A comparison of culture biomass evolution for the microalgae Scenedesmus spinosus in a tubular pilot photobioreactor of 1.6 m^(3)and a raceway pilot photobioreactor of 1.2 m^(3)was carried out,using a nutritional Z-8 ... A comparison of culture biomass evolution for the microalgae Scenedesmus spinosus in a tubular pilot photobioreactor of 1.6 m^(3)and a raceway pilot photobioreactor of 1.2 m^(3)was carried out,using a nutritional Z-8 medium with the injection of carbon dioxide,and using an electronic system for monitoring and control of operational variables.For three weeks of testing,each culture was exposed to three pH levels of 6.5,7.0 or 7.5,where random samples from both bioreactors were taken three times a week,to analyze pH,turbidity,transmittance at 640 nm and temperature.At the beginning and the end of culture,total solids were analyzed,and photographs were taken with a microscope to study the cell conditions of culture.This study revealed that the highest biomass production of Scenedesmus spinosus was obtained at pH 6.5 in the raceway photobioreactor,with a productivity of 371 g m^(-3) day^(-1),0.78%total solids,a turbidity of 858 NTU and 5%transmittance at the end of the culture. 展开更多
关键词 microalgae PHOTOBIOREACTOR BIOMASS RACEWAY TUBULAR
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Design and optimization of microalgae photobioreactors for treatment of nitrogen and phosphorus in wastewater
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作者 Shanyu Xie Yuanpeng Wang Qingbiao Li 《Chinese Journal of Chemical Engineering》 2025年第10期222-232,共11页
The use of microalgae to recover nitrogen and phosphorus from wastewater has garnered significant attention,positioning it as one of the most promising and sustainable strategies in modern wastewater treatment.While v... The use of microalgae to recover nitrogen and phosphorus from wastewater has garnered significant attention,positioning it as one of the most promising and sustainable strategies in modern wastewater treatment.While various photobioreactors(PBRs)configurations have been widely applied for microalgae cultivation,limited research has focused on optimizing PBR design specificallyto enhance nitrogen and phosphorus removal efficiency.The high operational costs of wastewater treatment,combined with the inherent variability of microalgal growth,have prompted the search for advanced solutions that improve nitrogen and phosphorus removal while minimizing resource consumption and enabling predictive process control.Recently,the integration of PBR systems with artificialintelligence and machine learning(AI/ML)modeling has emerged as a transformative approach to enhancing nutrient removal,particularly for nitrogen and phosphorus.This study firstsummarizes existing PBR designs tailored for diverse applications,then outlines strategies for system enhancement through the optimization of mixing methods,construction materials,light intensity,and light source configuration.Furthermore,computational fluiddynamics(CFD)and AI/ML modeling are presented as tools to guide the structural design and operational optimization of microalgae-based nitrogen and phosphorus removal processes.Finally,future research directions and key challenges are discussed. 展开更多
关键词 microalgae PHOTOBIOREACTOR Design Optimization Nitrogen phosphorus removal ARTIFICIALINTELLIGENCE
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Responses of antibiotic resistance genes and microbial community in the microalgae-bacteria system under sulfadiazine:Mechanisms and implications
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作者 Shengnan Li Yucan Xi +3 位作者 Ke Wang Nianhong Wan Haiyan Liu Shih-Hsin Ho 《Journal of Environmental Sciences》 2025年第11期443-456,共14页
Microalgae-bacteria system is an emerging alternative for sustainable wastewater treatment.Exploring the structure and diversity of microbial community in microalgae-bacteria system under sulfadiazine stress can contr... Microalgae-bacteria system is an emerging alternative for sustainable wastewater treatment.Exploring the structure and diversity of microbial community in microalgae-bacteria system under sulfadiazine stress can contribute to the understanding of the sulfadiazine behavior in environments.Furthermore,as important carriers of antibiotic resistance genes(ARGs),microalgae can influence the profiles of ARGs either directly or indirectly through the secretion of metabolites.However,the effects of sulfadiazine on ARGs dissemination of microalgae-bacteria systems remain underreported.Herein,the impacts of sulfadiazine(1 mg/L)on the structural diversity and metabolic activity of microorganisms were examined in microalgae-bacteria systems.Results showed thatmicroalgae-bacteria system could remove NH_(4)^(+)-N better(about 72.3%)than activated sludge system,and hydrolysis was the first step in sulfadiazine degradation.A high level of intI1(5.7×10^(4) copies/mL)was detected in the initial media of the microalgae-bacteria system.Microalgae could hamper the rate of horizontal gene transfer activation.Compared with activated sludge system,the abundance of sul genes(sul1,sul2,sul3,and sulA)was significantly lowered after treating with microalgae-bacteria system.Additionally,the number of proteins and the sum of polysaccharides in the extracellular polymeric substances of the activated sludge system were lower than those of themicroalgae-bacteria system.Microalgae can altermicrobial communities.The genus Rozellomycota predominated all samples.Fungi with relatively high abundance increased in the microalgae-bacteria system,including Dipodascaceae,Rhodotorula,and Geotrichum.These results offer valuable insights into the application processes involving microalgae-bacteria system. 展开更多
关键词 microalgae microalgae-bacteria consortia Antibiotic resistance genes Microbial community Chlorella pyrenoidosa SULFADIAZINE
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Microalgae-carrying nanomedicine for bioadhesive drug delivery for treating chemotherapy-induced intestinal injury
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作者 Jie Chen Bing Wang +1 位作者 Lan Shen Yongzhuo Huang 《Asian Journal of Pharmaceutical Sciences》 2025年第2期106-119,共14页
Gastrointestinal tract toxicity represents a serious adverse effect of chemotherapy,leading to reduced quality of life and survival.For instance,irinotecan(CPT-11)usually causes severe gastrointestinal toxicity,with a... Gastrointestinal tract toxicity represents a serious adverse effect of chemotherapy,leading to reduced quality of life and survival.For instance,irinotecan(CPT-11)usually causes severe gastrointestinal toxicity,with a lack of effective therapeutic interventions,making treatment often unsustainable.Therefore,development of an effective and safe therapy is crucial for improving chemotherapy efficacy and the patients’quality of life.In this work,we developed a novel approach involving the helical-shaped cyanobacterium microalgae,Spirulina platensis(SP),to carry the bornyl acetate(BA)-loaded chitosan nanoparticles to enhance drug retention in the small intestine.We demonstrated the protection effect of BA against chemotherapy-induced intestinal injury using an epithelial cell model.In a mouse model,orally administered BA-ChNPs@SP accumulated in the small intestine and attenuated inflammation by reducing dsDNA release and oxidative stress.This was concomitant with the restoration of the intestinal barrier and modulation of the immune microenvironment.This work suggests the promise of the microalgae-carrying nanomedicine strategy for treatment of intestinal diseases,emphasizing its potential in addressing chemotherapy-induced gastrointestinal complications. 展开更多
关键词 microalgae Bioadhesive delivery Chemotherapy-induced intestinal injury Bornyl acetate Macrophages
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Adaptations,cultivation and commercial prospects of polar microalgae
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作者 Kiat Fatt CHIA Chiew Yen WONG +10 位作者 Rhun Yian KOH Choy Sin LEE Soi Moi CHYE Yih Yih KOK Siti Aqlima AHMAD Peter CONVEY Leyla Cárdenas TAVIE WANG Wei LUO Jiangyi Veeranoot NISSAPATORN Chooi Ling LIM 《Advances in Polar Science》 2025年第1期18-40,共23页
Polar microalgae are microscopic organisms adapted to survive in cold and extreme habitats such as sea-ice,glaciers,lakes and snow.These microorganisms provide an essential basis as primary food sources in polar ecosy... Polar microalgae are microscopic organisms adapted to survive in cold and extreme habitats such as sea-ice,glaciers,lakes and snow.These microorganisms provide an essential basis as primary food sources in polar ecosystems.Despite their ecological importance,polar microalgae remain relatively unexplored compared to their tropical and temperate counterparts,largely due to the practical challenges of obtaining and maintaining material from the harsh polar environments.However,interest has recently surged due to their specific adaptations and potential for utilization in various fields.This review explores the survival strategies of polar microalgae and their commercial applications in healthcare and other fields.We also consider the processes involved in processing polar microalgae,from cultivation to extraction of bioactive compounds.Our findings highlight a growing need for research in this rapidly evolving field to unlock the potential of polar microalgae in multiple fields. 展开更多
关键词 polar microalgae microalgal adaptations microalgal processing potential commercial applications
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C22-Ceramide Derived from Marine Microalgae Emiliania huxleyi Induces Melanosomal Autophagy via JNK/c-Jun Signaling Pathway in Mouse B16 Melanoma Cells
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作者 WAN Jiyue MA Hui +7 位作者 XU Yuxuan ZHANG Shumiao LI Jian LI Guiling HUANG Shiying YE Xiaotong ZHANG Zhengxiao LIU Jingwen 《Journal of Ocean University of China》 2025年第3期792-808,共17页
Melanosomes are specialized membrane-bound organelles within which melanin is synthesized and stored.The levels of melanin can be effectively reduced by inhibiting melanin synthesis or promoting melanosome degradation... Melanosomes are specialized membrane-bound organelles within which melanin is synthesized and stored.The levels of melanin can be effectively reduced by inhibiting melanin synthesis or promoting melanosome degradation via autophagy.Ceramide,a central molecule in sphingolipid metabolism,has been widely implicated in the regulation of autophagy.Few researchers have addressed the potential effects of ceramide analogs on suppressing melanin synthesis.However,whether ceramide can induce melanosome autophagy and the potential autophagy-dependent mechanism underlying this phenomenon remain unknown.Here,an active compound from the marine microalgae Emiliania huxleyi extract was firstly isolated and identified as a long-chain C22-ceramide(C22-Cer).In vitro results of mouse B16 melanoma cell experiments showed that treatment with 2-5µmol/L C22-Cer significantly suppressed the increase ofα-MSH-induced melanin levels and tyrosinase activity without cytotoxicity.C22-Cer induced typical hallmarks of autophagy such as accumulation of autophagosomes,enhanced autophagic flux and microtubule-associated protein light chain 3,LC3-II expression,and p62 degradation through activating c-Jun N-terminal kinase(JNK)directly.Furthermore,C22-Cer activated JNK-Bcl-2 signaling,dissociated the Beclin1/Bcl-2 complex,and induced melanosome autophagy without affecting the expression of MITF.Besides,the Ca^(2+)influx induced by treatment with C22-Cer further increased the substantial accumulation of autophagosomes.Together,we found a novel marine-derived compound,C22-Cer,targeting JNK pathway and Ca^(2+)signaling to induce melanosome autophagy and suppress melanin accumulation in B16 cells.This study implicates that C22-Cer might be a potential therapeutic mediator against skin pigmentation in mammals. 展开更多
关键词 marine microalgae Emiliania huxleyi C22-ceramide melanosomal autophagy JNKc-Jun signaling pathway mouse B16 cells
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黄丝藻营养特点及用于饲料开发的研究进展
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作者 陈林 任英豪 +6 位作者 周文俊 加晶 陈昱 张明 王佳宁 刘天中 吕雪峰 《中国饲料》 北大核心 2026年第3期179-188,共10页
黄丝藻的油脂、蛋白质和碳水化合物比例均衡,富含多不饱和脂肪酸和β-葡聚糖等功能活性成分。此外,黄丝藻生长快、环境耐受性强,易于大规模获得。饲料中适量添加黄丝藻或其功能成分对多种水产动物和畜禽的产品品质、生长和动物健康具有... 黄丝藻的油脂、蛋白质和碳水化合物比例均衡,富含多不饱和脂肪酸和β-葡聚糖等功能活性成分。此外,黄丝藻生长快、环境耐受性强,易于大规模获得。饲料中适量添加黄丝藻或其功能成分对多种水产动物和畜禽的产品品质、生长和动物健康具有积极影响。本文综述了黄丝藻的营养特点、生产技术及其在动物饲料中的应用研究进展,并对黄丝藻饲料应用的研究方向进行了展望,旨在为推动黄丝藻在饲料中的规模化应用提供参考。 展开更多
关键词 黄丝藻 微藻 饲料 二十碳五烯酸 棕榈油酸 Β-葡聚糖
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熔融氢氧盐体系微藻颗粒热化学制氢特性及结构演化机制
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作者 李俊 雷玲 +5 位作者 曹文轩 朱瀚 钟典 曾阔 杨海平 陈汉平 《燃料化学学报(中英文)》 北大核心 2026年第3期136-145,共10页
本研究旨在探究微藻颗粒在熔融氢氧盐(80%NaOH-20%Na_(2)CO_(3))体系中的热化学转化行为对氢气生成的影响。通过对比有无熔融盐条件下的微藻颗粒温度演变、气体释放特性及结构演化规律,并结合焦炭碱化反应实验,分析了熔融盐对微藻颗粒... 本研究旨在探究微藻颗粒在熔融氢氧盐(80%NaOH-20%Na_(2)CO_(3))体系中的热化学转化行为对氢气生成的影响。通过对比有无熔融盐条件下的微藻颗粒温度演变、气体释放特性及结构演化规律,并结合焦炭碱化反应实验,分析了熔融盐对微藻颗粒反应路径及制氢行为的调控机制。结果表明,熔融盐显著提升了颗粒内部传热效率,中心升温速率达177℃/s,有效缓解了颗粒传热滞后。同时,熔融盐通过渗透、侵蚀与催化作用促进了颗粒孔隙发育,颗粒反应10 s后的孔隙率增幅达53.2%–104.3%;并显著提升了转化效率,反应主导路径在反应70 s后即转为焦炭碱化反应。在高于600℃提高升温速率时,焦炭碱化反应的氢气产率提升更为显著,主要归因于熔融盐的催化作用与快速升温过程对挥发分重整的协同促进效应。本研究为深入理解熔融氢氧盐体系生物质高效制氢的机制提供了理论依据。 展开更多
关键词 熔融氢氧盐 微藻颗粒 结构演化 制氢 焦炭碱化
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Fluorescence-assisted Image Analysis of Harmful Microalgae 被引量:1
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作者 王学民 孙勇 曹红宝 《Marine Science Bulletin》 CAS 2006年第1期75-82,共8页
In order to realize the detection and analysis of microalgae in sediment samples with complex scenes, the project takes advantage of the character of microalgae that they can auto-fluoresce when exposed to the illumin... In order to realize the detection and analysis of microalgae in sediment samples with complex scenes, the project takes advantage of the character of microalgae that they can auto-fluoresce when exposed to the illumination of certain exciation waves. The project takes grey-scale and fluorescent pictures of microalgae in the same field of view and uses the image processing technique to deal with the images, such as threshold segmentation, contour and texture analysis and pattern recognition. The results show that the fluorescent image can effectively elimate the yawp in the complex background and make the consequent image processing more effective and easy. Then the project comes to the conclusion that fluorescence-assisted image processing can realize the detection and analysis of microalgae in sediment samples containing complex scenes. 展开更多
关键词 harmful microalgae image segmentation FLUORESCENCE
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四种微藻提取物对谷子生长和生化组分的影响
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作者 赵璐 宋庆辉 +7 位作者 钟志海 崔红利 刘正一 冯大伟 李丁军 镡玉玲 白泽文 张新明 《分子植物育种》 北大核心 2026年第2期496-502,共7页
微藻具有生物刺激素的特性,不同藻种内含的活性物质和提取方式不同,因此不同藻种对植物的影响可能表现出差异。为了探究不同藻种的活性物质及其提取方式对植物的影响,本研究检测和分析了埃式小球藻、莱茵衣藻、极大螺旋藻和雨生红球藻... 微藻具有生物刺激素的特性,不同藻种内含的活性物质和提取方式不同,因此不同藻种对植物的影响可能表现出差异。为了探究不同藻种的活性物质及其提取方式对植物的影响,本研究检测和分析了埃式小球藻、莱茵衣藻、极大螺旋藻和雨生红球藻的水提液和醇提液对谷子生长和生化组分的影响。结果表明,埃式小球藻和极大螺旋藻水提液和醇提液增加了谷子根长和茎长,对茎生长的促进作用比对根伸长的促进作用更好,且醇提液的效果更好。埃式小球藻和极大螺旋藻水提液和醇提液提高了谷子根系活力和叶绿素含量,促进了谷子鲜重的增加。此外,雨生红球藻醇提液也促进了谷子的生长和根系活力。四种微藻的水提液和醇提液对谷子的可溶性糖和蛋白含量以及过氧化物酶活性有着不同的改善作用。总体来看,埃式小球藻提取液对谷子的促生效果最好,但同一藻种在不同的提取方法下对谷子的影响存在显著差异。该研究体现了不同提取方法下四种微藻提取物对谷子生长和生化组分的影响和差异,为后续相关研究提供了参考。 展开更多
关键词 微藻 提取 谷子 生长 生化组分
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活性微生态水凝胶促进皮肤创面的愈合 被引量:1
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作者 黄新旭 张鑫 王剑 《中国组织工程研究》 北大核心 2026年第2期489-498,共10页
背景:活性微生态水凝胶是创面敷料研究领域的一大热点,受到广泛关注。目的:概述活性微生态水凝胶的基本特点与优势,综述近年来各种活性微生态水凝胶在皮肤创面修复中的应用进展。方法:以“cell,probiotics,phage,chlorella,algae,living... 背景:活性微生态水凝胶是创面敷料研究领域的一大热点,受到广泛关注。目的:概述活性微生态水凝胶的基本特点与优势,综述近年来各种活性微生态水凝胶在皮肤创面修复中的应用进展。方法:以“cell,probiotics,phage,chlorella,algae,living microecological,hydrogel,skin,wound healing,wound repair”为英文检索词,以“细胞,益生菌,噬菌体,小球藻,微藻,活性微生态,水凝胶,皮肤,伤口愈合,伤口修复”为中文检索词,在Web of Science、PubMed、中国知网及万方数据库进行文献检索,文献检索时限为各数据库建库至2024年。按照排除和纳入标准筛选纳入文献,最终纳入108篇文献进行综述。结果与结论:活性微生态水凝胶具有良好的生物相容性,能为负载的生物提供适宜的生存环境,并在活性生物与皮肤创面之间发挥屏障作用,避免潜在威胁。相较于传统伤口敷料,活性微生态水凝胶的作用是可持续可更新的,生物调节能使创面处微环境保持相对稳定的状态,可以长时间为创面愈合提供适宜条件,减少频繁更换敷料给皮肤创面造成的额外创伤。相较于直接使用活性生物促进皮肤创面愈合,活性微生态水凝胶能提高生物的存活率,保障其发挥生物调节作用。活性微生态水凝胶主要是通过调控创面愈合进程中“炎症”和“增殖”这两阶段来促进皮肤创面愈合。现有的活性微生态水凝胶主要负载细胞、益生菌、微藻、噬菌体这几类生物,赋予了水凝胶不同的生物特性,使其通过释放创面愈合所需物质或者改善创面环境等促进皮肤创面愈合,具有较大的应用潜力。为进一步扩大活性微生态水凝胶的实际临床运用,未来还需要进一步深入把控水凝胶中活性生物的生物安全风险,避免潜在的生物威胁,并需要研究更能适应人体皮肤创面复杂变化且能负载活性生物的水凝胶基质。 展开更多
关键词 水凝胶 创面愈合 生物活性材料 微生态 细胞 益生菌 微藻 噬菌体 工程化皮肤材料
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基于文献计量学的氟喹诺酮类抗生素对微藻的毒性效应与生态风险评估
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作者 孙静薇 王馨悦 +5 位作者 张瑾 朱曙光 王啸宇 成潜 纪广振 谢明江 《环境科学研究》 北大核心 2026年第1期127-137,共11页
氟喹诺酮类(Fluoroquinolone,FQ)抗生素是一类应用广泛的抗菌药物,其使用后在水环境中大量残留,对生态环境构成了威胁。因此,为评估FQ类抗生素的生态风险,采用文献计量学的方法,系统总结了2000年1月1日−2025年7月1日WoS和CNKI数据库中关... 氟喹诺酮类(Fluoroquinolone,FQ)抗生素是一类应用广泛的抗菌药物,其使用后在水环境中大量残留,对生态环境构成了威胁。因此,为评估FQ类抗生素的生态风险,采用文献计量学的方法,系统总结了2000年1月1日−2025年7月1日WoS和CNKI数据库中关于FQ类抗生素毒性研究方面的相关文献,全面分析了5种代表性FQ类抗生素−诺氟沙星(NFLX)、氧氟沙星(OFLX)、恩诺沙星(ENR)、环丙沙星(CIP)和加替沙星(GAT)对微藻的毒性效应与作用机制,并采用风险熵值法评估了其生态风险。结果表明:①2000年1月1日−2025年7月1日,关于FQ类抗生素毒性研究方面的发文量和被引次数总体上处于波动上升趋势,其中,中国的发文量与被引次数综合排名最高。文献来源最多的学科是环境科学与资源利用,主要集中在FQ类抗生素对微藻毒性、生态风险等方面的研究。②FQ类抗生素对微藻的毒性效应与受试生物、抗生素种类、暴露浓度和暴露时间以及复合污染状态等有关,其毒性作用机制为细胞结构被破坏,细胞内积累大量的活性氧(ROS),导致光合作用减弱,蛋白质含量下降,并引起细胞膜脂质化。③FQ类抗生素在水环境、土壤和沉积物中的残留浓度相对较高,且在不同水域中FQ类抗生素含量不同,部分水域的抗生素处于中高风险水平。建议未来开展FQ类抗生素的联合毒性效应,并从分子水平探讨其毒性作用机制,抗性基因在微藻中的迁移转化机制,以及低剂量长期暴露下FQ类抗生素对生态系统影响等方面的研究工作,以期为FQ类抗生素的污染治理提供参考。 展开更多
关键词 氟喹诺酮类(FQ类)抗生素 微藻 作用机制 生态风险
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真菌-微藻共生体技术及其在废水处理中的研究进展 被引量:1
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作者 梅丹娅 冯晓丽 +2 位作者 李杰 颜晓林 李潜 《生物工程学报》 北大核心 2026年第1期1-9,共9页
真菌-微藻共生体技术因环境友好、处理效率高、节能降碳且能实现废水资源化,已成为最具前景的废水生物处理技术之一。本文首先概述了真菌-微藻共生体技术的发展历程,进而总结了真菌-微藻共生体可能的形成机制及影响因素,最后综述了该技... 真菌-微藻共生体技术因环境友好、处理效率高、节能降碳且能实现废水资源化,已成为最具前景的废水生物处理技术之一。本文首先概述了真菌-微藻共生体技术的发展历程,进而总结了真菌-微藻共生体可能的形成机制及影响因素,最后综述了该技术在废水处理领域的研究进展,并展望了其未来发展前景,以期为真菌-微藻共生体技术的深入研究和工程化应用提供理论参考与实践指导。 展开更多
关键词 微藻生物技术 真菌-微藻共生体 微藻固定化 废水处理与资源化 共培养
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Preliminary screening of antimicrobial and antitumor activities from cultivated microalgaes
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作者 邓伟 王雪青 宋文军 《Marine Science Bulletin》 CAS 2011年第1期60-70,共11页
Hydrophilic and lipophilic extracts were prepared from 8 microalgal strains, and screened for antimicrobial and antitumor activities. Antimicrobial activity was determined by observing bacterial ( S. aureus, Bacillus... Hydrophilic and lipophilic extracts were prepared from 8 microalgal strains, and screened for antimicrobial and antitumor activities. Antimicrobial activity was determined by observing bacterial ( S. aureus, Bacillus subtilis and Escherichia coh~ and fungal(Aspergillus niger and Penicillium chrysogenum) growth inhibition. All the microalgae had different degrees of antimicrobial activity against one or more microbe - tested, and 56.47% of the extracts showing the anti-S.aureus activity exhibited the antibacterial activity against (MRSA). Cytotoxic activities were measured in vitro against human cancer cell lines HeLa by the MTT assay. Most of these extracts showed potent activity against the growth of the tumor cells, especially the intracellular lipophilic extracts from Isochrysis galbana Parke 3011 and Isochrysis galbana Parke H29, which exhibited strong antitumor activity against HeLa cell lines. The overall results of this study indicate that the extracts from microalgae represent a potential sources of medicine for the treatment of infectious and cancer diseases. 展开更多
关键词 microalgae SCREENING ANTIMICROBIAL ANTITUMOR
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2-氯乙基乙基硫醚暴露对淡水微藻光合代谢的影响及毒理效应
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作者 王莹 郑升 +3 位作者 赖金龙 付倩 张宇 罗学刚 《生态毒理学报》 北大核心 2026年第1期503-513,共11页
硫芥类化合物模拟剂2-氯乙基乙基硫醚(2-CEES)因潜在环境泄漏风险可能威胁水生生态系统,但其对淡水微藻的水生态毒理效应鲜有报道。本研究以9种淡水微藻(含蓝藻、绿藻、红藻)为对象,经2-CEES暴露后,分析藻液理化参数、叶绿素荧光动力学... 硫芥类化合物模拟剂2-氯乙基乙基硫醚(2-CEES)因潜在环境泄漏风险可能威胁水生生态系统,但其对淡水微藻的水生态毒理效应鲜有报道。本研究以9种淡水微藻(含蓝藻、绿藻、红藻)为对象,经2-CEES暴露后,分析藻液理化参数、叶绿素荧光动力学及微藻代谢谱的变化,解析2-CEES暴露对微藻光合电子传递链与碳代谢途径的毒理机制。结果显示,2-CEES导致微藻pH显著降低(2.6%~13.0%)、电导率升高1.93%~10.29%;其中,紫球藻和片状微囊藻生长受抑制最显著,表现出明显的种间差异。藻类叶绿素荧光参数显示,经2-CEES暴露,7种微藻光系统Ⅱ(PSⅡ)最大光化学效率(F_(v)/F_(m))显著降低,单位反应中心光能捕获(ABS/RC)与热耗散(DI_(o)/RC)增强,但电子传递活性(ET_(o)/RC)受抑,表明微藻光反应能量转化效率下降。代谢组学分析共鉴定2404个代谢物,KEGG富集通路显示,14种碳水化合物显著富集于糖酵解、磷酸戊糖途径(PPP)及卡尔文循环,其中10种代谢物在处理组间呈现显著性差异(P<0.05)。结果表明,2-CEES通过破坏PSⅡ反应中心电子传递、诱导代谢能量再分配,抑制微藻光合碳同化效率,其毒性效应具有显著种属特异性,该结果可为硫芥类污染物生态风险评估及生物标志物开发提供理论依据。 展开更多
关键词 2-氯乙基乙基硫醚 淡水微藻 光合代谢 叶绿素荧光动力学 生态风险评估
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Study on Tolerance and Biosorption of Various Microalgae Species to Arsenic
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作者 李妍丽 柯林 《Agricultural Science & Technology》 CAS 2012年第6期1303-1308,1327,共7页
[Objective] This study aimed to select microalgae species which are capable to effectively remove arsenic contamination from water under natural conditions. [Method] Four microalgae species [Chlorella sp. (zfsaia), ... [Objective] This study aimed to select microalgae species which are capable to effectively remove arsenic contamination from water under natural conditions. [Method] Four microalgae species [Chlorella sp. (zfsaia), Chlorella minata, Chlorella vulgaris and Selenastrum capricormulum] were used as experimental materials and cultured with six different concentrations of As (Ⅲ) (0.5, 1.0, 2.0, 5.0, 10.0, 20.0 mg/L). Biomass, chlorophyll a content and other physiological indicators were determined to investigate the arsenic tolerance and biosorption of four microalgae species. [Result] Chlorella sp. is sensitive to arsenic toxicity, its growth was inhibited when arsenic concentration exceeded 10 mg/L, with an EC 50 of 17.32 mg/L; when the arsenic concentration was 0-20 mg/L, growth of S.c, ww1 and C.v was not affected, which showed relatively high tolerance to arsenic, with arsenic removal rates of 77.02% , 72.18% and 81.36% respectively after 24 h. [Conclusion] This study indicates that microalgae have good application prospects for processing arsenic wastewater and being indicator plants of arsenic wastewater. 展开更多
关键词 As(Ⅲ) microalgae Toxicity effect BIOSORPTION
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小球藻驱动6PPDQ的降解动力学过程和机制
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作者 陈书杨 卢坤 +2 位作者 郭芳婕 李娜 汪美贞 《生态毒理学报》 北大核心 2026年第1期306-317,共12页
由于城市雨水径流和水体中存在大量的轮胎磨损颗粒物,导致N-(1,3-二甲基丁基)-N’-苯基对苯二胺-醌(6PPDQ)对自然水环境的威胁越来越受到关注。因此,亟须开发绿色、高效的处理技术以实现对水中6PPDQ的去除。本研究系统探究了小球藻对6P... 由于城市雨水径流和水体中存在大量的轮胎磨损颗粒物,导致N-(1,3-二甲基丁基)-N’-苯基对苯二胺-醌(6PPDQ)对自然水环境的威胁越来越受到关注。因此,亟须开发绿色、高效的处理技术以实现对水中6PPDQ的去除。本研究系统探究了小球藻对6PPDQ的降解动力学过程和机制。结果表明,在96 h内小球藻对6PPDQ的去除率为70%~84%,且去除过程符合假一级动力学模型。生物吸附与生物降解的协同作用是小球藻驱动6PPDQ去除的主要机理。一方面,6PPDQ能够诱导小球藻细胞分泌更多的胞外聚合物(EPS),进而提供了更多的吸附位点。另一方面,6PPDQ能够激活CYP450、GST和POD的活性,协同实现对6PPDQ的生物降解。分子对接结果进一步表明,6PPDQ与CYP450、GST和POD的结合能分别是-33.9、-28.5、-27.6 kJ·mol^(-1),说明CYP450为6PPDQ初始代谢的关键酶。总的来说,本研究所揭示的微藻驱动6PPDQ降解的动力学过程和机制,为开发基于微藻的有毒有机污染物的去除技术提供了理论支撑。 展开更多
关键词 6PPD-醌 微藻 生物降解 胞外聚合物 CYP450 分子对接
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有机碳源对小球衣藻生长和聚集的影响
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作者 贾伟 陈国炜 +2 位作者 汪锞 吴雪菲 刘丽 《合肥工业大学学报(自然科学版)》 北大核心 2026年第2期194-201,共8页
由于碳源作为主要营养物质对于微藻的培养过程有着重要影响,文章以小球衣藻(Chlamydomonas microsphaera)为研究对象,探究在葡萄糖和乙酸钠2种有机碳源影响下,微藻生长和聚集的变化。研究结果表明:一次性投加化学需氧量(chemical oxygen... 由于碳源作为主要营养物质对于微藻的培养过程有着重要影响,文章以小球衣藻(Chlamydomonas microsphaera)为研究对象,探究在葡萄糖和乙酸钠2种有机碳源影响下,微藻生长和聚集的变化。研究结果表明:一次性投加化学需氧量(chemical oxygen demand,COD)为100mg/L的乙酸钠时,菌藻细胞数量比为3∶1的菌藻体系中有最大微藻聚集率63%,是纯藻对照组的2.2倍,是无碳源实验组的1.8倍;乙酸钠和葡萄糖对于微藻的聚集和生长均有促进作用,且乙酸钠促进效果优于葡萄糖,但是随着其投加量增加,促进微藻聚集和生长的效果下降,甚至出现抑制生长的情况;此外,相较于一次性投加碳源,分批式投加碳源更有利于微藻生长。 展开更多
关键词 小球衣藻 菌藻互作 微藻聚集率 有机碳源
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微藻及其生物活性物质在水产饲料中的应用
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作者 赵展铖 王桂芹 刘冰莉 《饲料工业》 北大核心 2026年第5期17-29,共13页
微藻富含优质蛋白、脂质及多种生物活性物质(如ω-3多不饱和脂肪酸、色素和β-1,3-葡聚糖等),可部分替代水产饲料中的鱼粉和鱼油,其生物活性物质还可作为饲料添加剂,促进水产动物生长和增强机体免疫。文章综述了微藻及其生物活性物质在... 微藻富含优质蛋白、脂质及多种生物活性物质(如ω-3多不饱和脂肪酸、色素和β-1,3-葡聚糖等),可部分替代水产饲料中的鱼粉和鱼油,其生物活性物质还可作为饲料添加剂,促进水产动物生长和增强机体免疫。文章综述了微藻及其生物活性物质在水产饲料中的研究进展与应用现状,分析了其替代传统饲料原料的优势与不足,并从生物技术提升产量和产业化应用的角度,探讨了微藻在新型水产饲料中的研发方向,为相关研究和实践提供理论参考与指导。 展开更多
关键词 微藻 水产饲料 生物活性物质 功能 应用
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