Joining dissimilar materials encounters significant engineering challenges due to the contrast in material properties that makes conventional welding not feasible.Magnetic Pulse Welding(MPW)offers a solidstate joining...Joining dissimilar materials encounters significant engineering challenges due to the contrast in material properties that makes conventional welding not feasible.Magnetic Pulse Welding(MPW)offers a solidstate joining technique that overcomes these issues by using impact to create strong bonds without melting the substrate materials.This study investigates the weldability of aluminum alloy Al-5754 with Al-7075 and MARS 380 steel,used in armouring solutions of defense systems,by the use of MPW.In this work,weldability windows are investigated by varying standoff distances between the coating material and its substrate(0.25-4.5 mm)and discharge energies(5-13 kJ)with both O-shape and U-shape inductors.Mechanical strength of the welded joints were assessed through single lap shear tests,identifying optimal welding parameters.Then,the velocity profiles of the flyer plates were measured using heterodyne velocimetry to understand the dynamics of the impact.Then,substructures assembled with the optimal welding conditions were subjected to ballistic testing using 7.62 mm×51 mm NATO and 9 mm×19 mm Parabellum munitions to evaluate the resilience of the welds under ballistic impact.The outcomes demonstrate that MPW effectively joins Al-5754 with both Al-7075 and MARS 380,producing robust welds capable of withstanding ballistic impacts under certain conditions.This research advances the application of MPW in lightweight ballistic protection of defense systems,contributing to the development of more resilient and lighter protective structures.展开更多
It is challenging to diagnose isolated hyperbilirubinemia with rare and complex etiologies under the constraints of traditional testing conditions.Herein,we present a rare case of coexisting Gilbert syndrome(GS)and er...It is challenging to diagnose isolated hyperbilirubinemia with rare and complex etiologies under the constraints of traditional testing conditions.Herein,we present a rare case of coexisting Gilbert syndrome(GS)and erythropoietic protoporphyria(EPP),which has not been previously documented.CASE SUMMARY We present a rare case of coexisting GS and EPP in a 23-year-old Chinese male with a long history of jaundice and recently found splenomegaly.Serial nonspecific hemolysis screening tests yielded inconsistent results,and investigations for common hemolytic etiologies were negative.However,Levitt’s carbon monoxide breath test,which measures erythrocyte lifespan(the gold-standard marker of hemolysis),demonstrated significant hemolysis,revealing a markedly shortened erythrocyte lifespan of 11 days(normal average 120 days).Genetic testing subsequently confirmed EPP with a homozygous ferrochelatase gene mutation and GS with a heterozygous uridine diphosphate glucuronosyl trans-ferase 1A1 gene mutation.CONCLUSION The rapid,non-invasive Levitt’s carbon monoxide breath test resolved the diagnostic challenge posed by a rare and complex cause of hyperbilirubinemia.展开更多
There exists an increasing need for Milli-Arc-Seconds(MAS)accuracy pointing measurement for current and future space systems.To meet the 0.1″space pointing measurement accuracy requirements of spacecraft in future,th...There exists an increasing need for Milli-Arc-Seconds(MAS)accuracy pointing measurement for current and future space systems.To meet the 0.1″space pointing measurement accuracy requirements of spacecraft in future,the influence of spacecraft micro-vibration on a 0.1″Space Pointing Measuring Instrument(SPMI)is studied.A Quasi-Zero Stiffness Device(QZSD)with adaptive adjustment and variable stroke was proposed.Then,a series of micro-vibration experiments of the SPMI were carried out.The influence of the micro-vibration generated by Guidance Navigation Control(GNC)attitude control components under different attitudes on the SPMI was analyzed.Point spread function of image motion in micro-vibration was also derived.Further,the changes of image motion under the micro-vibration environment were evaluated by extracting the gray centroid of the images,and the experiment processes and results are deeply discussed.The results show that the firstorder frequency of the QZSD system is 0.114 Hz,and it is induced by a double pendulum system;the image motion of single flywheel spinning reached 0.015 pixels;whilst the image motion reached 0.03 pixels when three flywheels are combined spinning.These latest findings provide a beneficial theoretical and technical support for the development of spacecraft with 0·1″pointing accuracy.展开更多
Micro-vibration is an important factor affecting the imaging quality and pointing accu-racy of the in-orbit satellites.To address the problem of micro-vibration compensation,a general summary for modeling,analysis,sup...Micro-vibration is an important factor affecting the imaging quality and pointing accu-racy of the in-orbit satellites.To address the problem of micro-vibration compensation,a general summary for modeling,analysis,suppression,and compensation approach should be outlined.In this review,micro-vibration characteristics and its impacts on the payloads are firstly analyzed.Afterwards,methods for micro-vibration measurement are provided.In detail,the principles and practical applications of these methods are introduced.Then,advanced technologies for micro-vibration suppression are summarized from micro-vibration source attenuation,transfer path opti-mization and sensitive load isolation.Two approaches have been found to be effective for micro-vibration compensation.The one is the Line-of-Sight(LOS)stabilization assisted with Inertial Ref-erence Unit(IRU).The other is using image restoration technology to remove the blur caused by platform jitter.The compensation technique and research status of the two techniques are reviewed.This work will provide researchers with technical guidelines for micro-vibration suppression.展开更多
In this paper, a soft active isolator（SAI） derived from a voice coil motor is studied to determine its abilities as a micro-vibration isolation device for sensitive satellite payloads. Firstly,the two most important...In this paper, a soft active isolator（SAI） derived from a voice coil motor is studied to determine its abilities as a micro-vibration isolation device for sensitive satellite payloads. Firstly,the two most important parts of the SAI, the mechanical unit and the low-noise driver, are designed and manufactured. Then, a rigid-flexible coupling dynamic model of the SAI is built, and a dynamic analysis is conducted. Furthermore, a controller with a sky-hook damper is designed. Finally,results from the performance tests of the mechanical/electronic parts and the isolation experiments are presented. The SAI attenuations are found to be more than 20 d B above 5 Hz, and the control effect is stable.展开更多
Magneto-rheological elastomers （MILEs） are used to construct composite structures for micro-vibration control of equipment under stochastic support-motion excitations. The dynamic behavior of MREs as a smart viscoel...Magneto-rheological elastomers （MILEs） are used to construct composite structures for micro-vibration control of equipment under stochastic support-motion excitations. The dynamic behavior of MREs as a smart viscoelastic material is characterized by a complex modulus dependent on vibration frequency and controllable by external magnetic fields. Frequency-domain solution methods for stochastic micro-vibration response analysis of the MRE-based structural systems are developed to derive the system frequency-response function matrices and the expressions of the velocity response spectrum. With these equations, the root-mean-square （RMS） velocity responses in terms of the one-third octave frequency band spectrum can be calculated. Further, the optimization problem of the complex moduli of the MRE cores is defined by minimizing the velocity response spectra and the RMS velocity responses through altering the applied magnetic fields. Simulation results illustrate the influences of MRE parameters on the RMS velocity responses and the high response reduction capacities of the MRE-based structures. In addition, the developed frequency-domain analysis methods are applicable to sandwich beam structures with arbitrary cores characterized by complex shear moduli under stochastic excitations described by power spectral density functions, and are valid for a wide frequency range.展开更多
Based on the 1 550 nm all-fiber pulsed laser Doppler vibrometer(LDV) system independently developed by our laboratory, empirical mode decomposition(EMD) and optimally modified Log-spectral amplitude estimator(OM-LSA) ...Based on the 1 550 nm all-fiber pulsed laser Doppler vibrometer(LDV) system independently developed by our laboratory, empirical mode decomposition(EMD) and optimally modified Log-spectral amplitude estimator(OM-LSA) algorithms are associated to separate the speech micro-vibration from the target macro motion. This combined algorithm compensates for the weakness of the EMD algorithm in denoising and the inability of the OM-LSA algorithm on signal separation, achieving separation and simultaneous acquisition of the macro motion and speech micro-vibration of a target. The experimental results indicate that using this combined algorithm, the LDV system can functionally operate within 30 m and gain a 4.21 d B promotion in the signal-to-noise ratio(SNR) relative to a traditional OM-LSA algorithm.展开更多
Environmental micro-vibration is one of the key factors impacting the running of electronic workshop.Low frequency micro-vibration has a significant influence on the normal operation of high precision machining and te...Environmental micro-vibration is one of the key factors impacting the running of electronic workshop.Low frequency micro-vibration has a significant influence on the normal operation of high precision machining and testing equipment,and even causes irreversible damage to the equipment.Micro-vibration testing and response analysis are important to guide the vibration isolation design and ensure the stable operation of various precision equipment in the workshop.Parameters of Davidenkov model are fitted based on whale swarm optimization algorithm,and its applicability is verified.At the same time,taking the testing project of an electronic workshop raw land as an example,the micro-vibration response is analyzed.The results show that the nonlinear constitutive model constructed by whale optimization algorithm can simulate the dynamic nonlinear behavior of soil under the action of micro-vibration better.Compared with the traditional equivalent linearization method,the nonlinear constitutive model based on the whale optimization algorithm has a smaller acceleration response value.It can effectively suppress the“virtual resonance effect”produced by the equivalent linearization method.展开更多
To avoid the negative effects of disturbances on satellites,the characteristics of micro-vibration on flywheels are studied.Considering rotor imbalance,bearing imperfections and structural elasticity,the extended mode...To avoid the negative effects of disturbances on satellites,the characteristics of micro-vibration on flywheels are studied.Considering rotor imbalance,bearing imperfections and structural elasticity,the extended model of micro-vibration is established.In the feature extraction of micro-vibration,singular value decomposition combined with the improved Akaike Information Criterion(AIC-SVD)is applied to denoise.More robust and self-adaptable than the peak threshold denoising,AIC-SVD can effectively remove the noise components.Subsequently,the effective harmonic coefficients are extracted by the binning algorithm.The results show that the harmonic coefficients have great identification in frequency domain.Except for the fundamental frequency caused by rotor imbalance,the harmonics are also caused by the coupling of imperfections on bearing components.展开更多
This study investigated the vibration frequency in micro-vibration therapy (MVT) performed as a part of nursing care in Japan. We surveyed 31 nurses (25 women and 6 men) who performed MVT with accelerometers attached ...This study investigated the vibration frequency in micro-vibration therapy (MVT) performed as a part of nursing care in Japan. We surveyed 31 nurses (25 women and 6 men) who performed MVT with accelerometers attached to the backs of their hands, and the data obtained were analyzed. The mean vibration frequency was 8.3 Hz (standard deviation [SD]: 1.9 Hz) bilaterally, with a left-right difference of 0.8 Hz (SD: 1.1 Hz, right > left). Furthermore, vibration frequency was correlated with duration of MVT use (rs = 0.5, P < 0.01). The vibration frequency was higher in men (9.2 Hz, SD: 2.4 Hz) than in women (8.1 Hz, SD: 1.8 Hz), but this difference was not significant (P = 0.34). The vibrations of MVT are of a lower frequency than those of other vibration therapies.展开更多
NOx sensors, as a core component of diesel engine exhaust treatment system, play an important role in exhaust emission control, which can accurately and quickly detect the NOx and O2 concentration. It has become a nec...NOx sensors, as a core component of diesel engine exhaust treatment system, play an important role in exhaust emission control, which can accurately and quickly detect the NOx and O2 concentration. It has become a necessary option for the detection of existing exhaust emission standards. At present, there is limited and scattered information on knowledge and test methods of NOx sensors, the research of NOx sensors has become a challenging research topic at home and abroad. Based on these requirements, the article systematically integrates the knowledge of principle and testing methods. First of all, through introducing functional description of NOx sensors and the basic principle of NOx sensors, the relevant scholars can have an overall understanding of the product and master the operation mode of products. Secondly, the current status of performance test bench and methods of NOx sensors were described, which can contribute to having a clear understanding of the development process. After that, a new structure of NOx sensors test bench was purposed, which contains six major units including standard gas source, gas mixing unit, analyzer measurement unit, sensor measurement unit, data processing and display unit, exhaust gas treatment unit. And the test bench was validated. The experimental results show that the test bench has the advantages of high-repeatability, high reliability and low cost. And it can realize automatic detection of multiple target values, which is worthy further promotion. Thereby, the article can contribute to the development of its technology indirectly.展开更多
Advances in the identification of molecular biomarkers and the development of targeted therapies have enhanced the prognosis of patients with advanced gastric cancer.Several established biomarkers have been widely int...Advances in the identification of molecular biomarkers and the development of targeted therapies have enhanced the prognosis of patients with advanced gastric cancer.Several established biomarkers have been widely integrated into routine clinical diagnostics of gastric cancer to guide personalized treatment.Human epidermal growth factor receptor 2(HER2)was the first molecular biomarker to be used in gastric cancer with trastuzumab being the first approved targeted therapy for HER2-positive gastric cancer.Programmed death-ligand 1 positivity and microsatellite instability can guide the use of immunotherapies,such as pembrolizumab and nivolumab.More recently,zolbetuximab has been approved for patients with claudin 18.2-positive diseases in some countries.More targeted therapies,including savolitinib for MET-positive patients,are currently under clinical investigation.However,the clinical application of these diagnostic approaches could be hampered by many existing challenges,including invasive and costly sampling methods,variability in immunohistochemistry interpretation,high costs and long turnaround times for next-generation sequencing,the absence of standardized and clinically validated diagnostic cut-off values for some biomarkers,and tumor heterogeneity.Novel testing and analysis techniques,such as artificial intelligence-assisted image analysis and multiplex immunohistochemistry,and emerging therapeutic strategies,including combination therapies that integrate immune checkpoint inhibitors with targeted therapies,offer potential solutions to some of these challenges.This article reviews recent progress in gastric cancer testing,outlines current challenges,and explores future directions for biomarker testing and targeted therapy for gastric cancer.展开更多
The rapid progress in the construction of heavy-haul and high-speed railways has led to a surge in rail defects and unforeseen failures.Addressing this issue necessitates the implementation of more sophisticated rail ...The rapid progress in the construction of heavy-haul and high-speed railways has led to a surge in rail defects and unforeseen failures.Addressing this issue necessitates the implementation of more sophisticated rail inspection methods,specifically involving real-time,precise detection,and assessment of rail defects.Current applications fail to address the evolving requirements,prompting the need for advancements.This paper provides a summary of various types of rail defects and outlines both traditional and innovative non-destructive inspection techniques,examining their fundamental features,benefits,drawbacks,and practical suitability for railway track inspection.It also explores potential enhancements to equipment and software.The comprehensive review draws upon pertinent international research and review papers.Furthermore,the paper introduces a fusion of inspection methods aimed at enhancing the overall reliability of defect detection.展开更多
The purpose of this study is to analyze the application of ultrasonic non-destructive testing technology in bridge engineering.During the research phase,based on literature collection and reading,as well as the analys...The purpose of this study is to analyze the application of ultrasonic non-destructive testing technology in bridge engineering.During the research phase,based on literature collection and reading,as well as the analysis of bridge inspection materials,the principle of ultrasonic non-destructive testing technology and its adaptability to bridge engineering are elaborated.Subsequently,starting from the preparation work before inspection until damage assessment,the entire process of ultrasonic non-destructive testing is studied,and finally,a technical system of ultrasonic non-destructive testing for bridge engineering that runs through the entire process is formed.It is hoped that this article can provide technical reference value for relevant units in China,and promote the high-quality development of China’s bridge engineering from a macro perspective.展开更多
The mechanical behavior of cohesive soil is sensitized to drying-wetting cycles under confinements.However,the hydromechanical coupling effect has not been considered in current constitutive models.A macro-micro analy...The mechanical behavior of cohesive soil is sensitized to drying-wetting cycles under confinements.However,the hydromechanical coupling effect has not been considered in current constitutive models.A macro-micro analysis scheme is proposed in this paper to investigate the soil deformation behavior under the coupling of stress and drying-wetting cycles.A new device is developed based on CT(computerized tomography)workstation to apply certain normal and shear stresses on a soil specimen during drying-wetting cycles.A series of tests are conducted on a type of loess with various coupling of stress paths and drying-wetting cycles.At macroscopic level,stress sensor and laser sensor are used to acquire stress and strain,respectively.The shear and volumetric strain increase during the first few drying-wetting cycles and then become stable.The increase of the shear stress level or confining pressure would cause higher increase rate and the value of shear strain in the process of drying-wetting cycles.At microscopic level,the grayscale value(GSV)of CT scanning image is characterized as the proportion of soil particles to voids.A fabric state parameter is proposed to characterize soil microstructures under the influence of stress and drying-wetting cycle.Test results indicate that the macroand micro-responses show high consistence and relevance.The stress and drying-wetting cycles would both induce collapse of the soil microstructure,which dominants degradation of the soil mechanical properties.The evolution of the macro-mechanical property of soil exhibits a positive linear relationship with the micro-evolution of the fabric state parameter.展开更多
With the depletion of fossil fuels and increasing environmental concerns,the development of renewable energy,such as wave energy,has become a critical component of global energy strategies.However,challenges persist i...With the depletion of fossil fuels and increasing environmental concerns,the development of renewable energy,such as wave energy,has become a critical component of global energy strategies.However,challenges persist in the field testing methodologies for wave energy converters(WECs).In this paper,a numerical wave field of the Dawanshan Island Sea Area in Zhuhai City is constructed based on the MIKE21 SW wave model and by using an NCEP wind field driving model.In conjunction with the IEC-62600-100 standard,by taking site testing of the“Wanshan”wave energy converter on which a sea trial has been conducted in Dawanshan Island of Zhuhai city as an example,research on-site testing method for a wave energy converter has been carried out.The wave measurement position for the“Wanshan”converter was determined by combining statistically analyzed field data with a validated numerical wave model.By comparing a valid wave height at the position where a wave rider is located with a valid wave height at the position where the“Wanshan”wave energy converter is situated,the correlation coefficient between simulation and observed data reached 0.90,with a root-mean-square error of 0.19.The representativeness of wave measurement data during site testing is verified and can be used as a basis for calculating the input energy of the“Wanshan”wave energy converter.展开更多
Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the su...Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the substantial pressures exerted by vehicles,trains,and other forms of transportation,but also efficiently transfer these loads to the underlying foundation,ensuring the stability and longevity of the roadway.In recent years,advancements in subgrade engineering technology have propelled the industry towards smarter,greener,and more sustainable practices,particularly in the areas of intelligent monitoring,disaster management,and innovative construction methods.This paper reviews the application and methodologies of intelligent testing equipment,including cone penetration testing(CPT)devices,soil resistivity testers,and intelligent rebound testers,in subgrade engineering.It examines the operating principles,advantages,limitations,and application ranges of these tools in subgrade testing.Additionally,the paper evaluates the practical use of advanced equipment from both domestic and international perspectives,addressing the challenges encountered by various instruments in realworld applications.These devices enable precise,comprehensive testing and evaluation of subgrade conditions at different stages,providing real-time data analysis and intelligent early warnings.This supports effective subgrade health management and maintenance.As intelligent technologies continue to evolve and integrate,these tools will increasingly enhance the accuracy,efficiency,and sustainability of subgrade monitoring.展开更多
基金funded on the one hand by Agence de l'Innovation de Défense(AID)grant reference number 2021650044on the other hand by Ecole Centrale de Nantes。
文摘Joining dissimilar materials encounters significant engineering challenges due to the contrast in material properties that makes conventional welding not feasible.Magnetic Pulse Welding(MPW)offers a solidstate joining technique that overcomes these issues by using impact to create strong bonds without melting the substrate materials.This study investigates the weldability of aluminum alloy Al-5754 with Al-7075 and MARS 380 steel,used in armouring solutions of defense systems,by the use of MPW.In this work,weldability windows are investigated by varying standoff distances between the coating material and its substrate(0.25-4.5 mm)and discharge energies(5-13 kJ)with both O-shape and U-shape inductors.Mechanical strength of the welded joints were assessed through single lap shear tests,identifying optimal welding parameters.Then,the velocity profiles of the flyer plates were measured using heterodyne velocimetry to understand the dynamics of the impact.Then,substructures assembled with the optimal welding conditions were subjected to ballistic testing using 7.62 mm×51 mm NATO and 9 mm×19 mm Parabellum munitions to evaluate the resilience of the welds under ballistic impact.The outcomes demonstrate that MPW effectively joins Al-5754 with both Al-7075 and MARS 380,producing robust welds capable of withstanding ballistic impacts under certain conditions.This research advances the application of MPW in lightweight ballistic protection of defense systems,contributing to the development of more resilient and lighter protective structures.
文摘It is challenging to diagnose isolated hyperbilirubinemia with rare and complex etiologies under the constraints of traditional testing conditions.Herein,we present a rare case of coexisting Gilbert syndrome(GS)and erythropoietic protoporphyria(EPP),which has not been previously documented.CASE SUMMARY We present a rare case of coexisting GS and EPP in a 23-year-old Chinese male with a long history of jaundice and recently found splenomegaly.Serial nonspecific hemolysis screening tests yielded inconsistent results,and investigations for common hemolytic etiologies were negative.However,Levitt’s carbon monoxide breath test,which measures erythrocyte lifespan(the gold-standard marker of hemolysis),demonstrated significant hemolysis,revealing a markedly shortened erythrocyte lifespan of 11 days(normal average 120 days).Genetic testing subsequently confirmed EPP with a homozygous ferrochelatase gene mutation and GS with a heterozygous uridine diphosphate glucuronosyl trans-ferase 1A1 gene mutation.CONCLUSION The rapid,non-invasive Levitt’s carbon monoxide breath test resolved the diagnostic challenge posed by a rare and complex cause of hyperbilirubinemia.
基金the support from the National Natural Science Foundation of China(No.51905034,52275083)。
文摘There exists an increasing need for Milli-Arc-Seconds(MAS)accuracy pointing measurement for current and future space systems.To meet the 0.1″space pointing measurement accuracy requirements of spacecraft in future,the influence of spacecraft micro-vibration on a 0.1″Space Pointing Measuring Instrument(SPMI)is studied.A Quasi-Zero Stiffness Device(QZSD)with adaptive adjustment and variable stroke was proposed.Then,a series of micro-vibration experiments of the SPMI were carried out.The influence of the micro-vibration generated by Guidance Navigation Control(GNC)attitude control components under different attitudes on the SPMI was analyzed.Point spread function of image motion in micro-vibration was also derived.Further,the changes of image motion under the micro-vibration environment were evaluated by extracting the gray centroid of the images,and the experiment processes and results are deeply discussed.The results show that the firstorder frequency of the QZSD system is 0.114 Hz,and it is induced by a double pendulum system;the image motion of single flywheel spinning reached 0.015 pixels;whilst the image motion reached 0.03 pixels when three flywheels are combined spinning.These latest findings provide a beneficial theoretical and technical support for the development of spacecraft with 0·1″pointing accuracy.
基金supported by the National Natural Science Foundation of China (No.62203322)the China Postdoctoral Science Foundation (No.2022M712372)the Enlisting and Leading Program of the Taihu Laboratory of Deepsea Technological Science,China (No.2022JBGS03001).
文摘Micro-vibration is an important factor affecting the imaging quality and pointing accu-racy of the in-orbit satellites.To address the problem of micro-vibration compensation,a general summary for modeling,analysis,suppression,and compensation approach should be outlined.In this review,micro-vibration characteristics and its impacts on the payloads are firstly analyzed.Afterwards,methods for micro-vibration measurement are provided.In detail,the principles and practical applications of these methods are introduced.Then,advanced technologies for micro-vibration suppression are summarized from micro-vibration source attenuation,transfer path opti-mization and sensitive load isolation.Two approaches have been found to be effective for micro-vibration compensation.The one is the Line-of-Sight(LOS)stabilization assisted with Inertial Ref-erence Unit(IRU).The other is using image restoration technology to remove the blur caused by platform jitter.The compensation technique and research status of the two techniques are reviewed.This work will provide researchers with technical guidelines for micro-vibration suppression.
基金co-supported by the National Natural Science Foundation of China (No. 11302010)Shanghai Institute of Satellite Engineering (No. HT-2010-0753)
文摘In this paper, a soft active isolator（SAI） derived from a voice coil motor is studied to determine its abilities as a micro-vibration isolation device for sensitive satellite payloads. Firstly,the two most important parts of the SAI, the mechanical unit and the low-noise driver, are designed and manufactured. Then, a rigid-flexible coupling dynamic model of the SAI is built, and a dynamic analysis is conducted. Furthermore, a controller with a sky-hook damper is designed. Finally,results from the performance tests of the mechanical/electronic parts and the isolation experiments are presented. The SAI attenuations are found to be more than 20 d B above 5 Hz, and the control effect is stable.
基金Research Grants Council of the Hong Kong Special Administrative Region,China Under Grant No.PolyU 5252/07EThe Hong Kong Polytechnic University through the Development of Niche Areas Programme Under Grant No.1-BB95Zhejiang Provincial Natural Science Foundation of China Under Grant No.Y607087)
文摘Magneto-rheological elastomers （MILEs） are used to construct composite structures for micro-vibration control of equipment under stochastic support-motion excitations. The dynamic behavior of MREs as a smart viscoelastic material is characterized by a complex modulus dependent on vibration frequency and controllable by external magnetic fields. Frequency-domain solution methods for stochastic micro-vibration response analysis of the MRE-based structural systems are developed to derive the system frequency-response function matrices and the expressions of the velocity response spectrum. With these equations, the root-mean-square （RMS） velocity responses in terms of the one-third octave frequency band spectrum can be calculated. Further, the optimization problem of the complex moduli of the MRE cores is defined by minimizing the velocity response spectra and the RMS velocity responses through altering the applied magnetic fields. Simulation results illustrate the influences of MRE parameters on the RMS velocity responses and the high response reduction capacities of the MRE-based structures. In addition, the developed frequency-domain analysis methods are applicable to sandwich beam structures with arbitrary cores characterized by complex shear moduli under stochastic excitations described by power spectral density functions, and are valid for a wide frequency range.
基金supported by the National Natural Science Foundation of China (No.61805234)the Key Research Program of Frontier Science,CAS (No.QYZDB-SSWSLH014)the Foundation of State Key Laboratory of Laser Interaction with Matter (No.SKLLIM1704)。
文摘Based on the 1 550 nm all-fiber pulsed laser Doppler vibrometer(LDV) system independently developed by our laboratory, empirical mode decomposition(EMD) and optimally modified Log-spectral amplitude estimator(OM-LSA) algorithms are associated to separate the speech micro-vibration from the target macro motion. This combined algorithm compensates for the weakness of the EMD algorithm in denoising and the inability of the OM-LSA algorithm on signal separation, achieving separation and simultaneous acquisition of the macro motion and speech micro-vibration of a target. The experimental results indicate that using this combined algorithm, the LDV system can functionally operate within 30 m and gain a 4.21 d B promotion in the signal-to-noise ratio(SNR) relative to a traditional OM-LSA algorithm.
文摘Environmental micro-vibration is one of the key factors impacting the running of electronic workshop.Low frequency micro-vibration has a significant influence on the normal operation of high precision machining and testing equipment,and even causes irreversible damage to the equipment.Micro-vibration testing and response analysis are important to guide the vibration isolation design and ensure the stable operation of various precision equipment in the workshop.Parameters of Davidenkov model are fitted based on whale swarm optimization algorithm,and its applicability is verified.At the same time,taking the testing project of an electronic workshop raw land as an example,the micro-vibration response is analyzed.The results show that the nonlinear constitutive model constructed by whale optimization algorithm can simulate the dynamic nonlinear behavior of soil under the action of micro-vibration better.Compared with the traditional equivalent linearization method,the nonlinear constitutive model based on the whale optimization algorithm has a smaller acceleration response value.It can effectively suppress the“virtual resonance effect”produced by the equivalent linearization method.
基金National Natural Science Foundation of China(No.U1831123)Fundamental Research Funds for the Central Universities,China(No.2232017A3-04)。
文摘To avoid the negative effects of disturbances on satellites,the characteristics of micro-vibration on flywheels are studied.Considering rotor imbalance,bearing imperfections and structural elasticity,the extended model of micro-vibration is established.In the feature extraction of micro-vibration,singular value decomposition combined with the improved Akaike Information Criterion(AIC-SVD)is applied to denoise.More robust and self-adaptable than the peak threshold denoising,AIC-SVD can effectively remove the noise components.Subsequently,the effective harmonic coefficients are extracted by the binning algorithm.The results show that the harmonic coefficients have great identification in frequency domain.Except for the fundamental frequency caused by rotor imbalance,the harmonics are also caused by the coupling of imperfections on bearing components.
文摘This study investigated the vibration frequency in micro-vibration therapy (MVT) performed as a part of nursing care in Japan. We surveyed 31 nurses (25 women and 6 men) who performed MVT with accelerometers attached to the backs of their hands, and the data obtained were analyzed. The mean vibration frequency was 8.3 Hz (standard deviation [SD]: 1.9 Hz) bilaterally, with a left-right difference of 0.8 Hz (SD: 1.1 Hz, right > left). Furthermore, vibration frequency was correlated with duration of MVT use (rs = 0.5, P < 0.01). The vibration frequency was higher in men (9.2 Hz, SD: 2.4 Hz) than in women (8.1 Hz, SD: 1.8 Hz), but this difference was not significant (P = 0.34). The vibrations of MVT are of a lower frequency than those of other vibration therapies.
文摘NOx sensors, as a core component of diesel engine exhaust treatment system, play an important role in exhaust emission control, which can accurately and quickly detect the NOx and O2 concentration. It has become a necessary option for the detection of existing exhaust emission standards. At present, there is limited and scattered information on knowledge and test methods of NOx sensors, the research of NOx sensors has become a challenging research topic at home and abroad. Based on these requirements, the article systematically integrates the knowledge of principle and testing methods. First of all, through introducing functional description of NOx sensors and the basic principle of NOx sensors, the relevant scholars can have an overall understanding of the product and master the operation mode of products. Secondly, the current status of performance test bench and methods of NOx sensors were described, which can contribute to having a clear understanding of the development process. After that, a new structure of NOx sensors test bench was purposed, which contains six major units including standard gas source, gas mixing unit, analyzer measurement unit, sensor measurement unit, data processing and display unit, exhaust gas treatment unit. And the test bench was validated. The experimental results show that the test bench has the advantages of high-repeatability, high reliability and low cost. And it can realize automatic detection of multiple target values, which is worthy further promotion. Thereby, the article can contribute to the development of its technology indirectly.
基金support by grants from Capital’s Funds for Health Improvement and Research(Grant No.2024-2-1024)Beijing Natural Science Foundation(Grant No.7232018).
文摘Advances in the identification of molecular biomarkers and the development of targeted therapies have enhanced the prognosis of patients with advanced gastric cancer.Several established biomarkers have been widely integrated into routine clinical diagnostics of gastric cancer to guide personalized treatment.Human epidermal growth factor receptor 2(HER2)was the first molecular biomarker to be used in gastric cancer with trastuzumab being the first approved targeted therapy for HER2-positive gastric cancer.Programmed death-ligand 1 positivity and microsatellite instability can guide the use of immunotherapies,such as pembrolizumab and nivolumab.More recently,zolbetuximab has been approved for patients with claudin 18.2-positive diseases in some countries.More targeted therapies,including savolitinib for MET-positive patients,are currently under clinical investigation.However,the clinical application of these diagnostic approaches could be hampered by many existing challenges,including invasive and costly sampling methods,variability in immunohistochemistry interpretation,high costs and long turnaround times for next-generation sequencing,the absence of standardized and clinically validated diagnostic cut-off values for some biomarkers,and tumor heterogeneity.Novel testing and analysis techniques,such as artificial intelligence-assisted image analysis and multiplex immunohistochemistry,and emerging therapeutic strategies,including combination therapies that integrate immune checkpoint inhibitors with targeted therapies,offer potential solutions to some of these challenges.This article reviews recent progress in gastric cancer testing,outlines current challenges,and explores future directions for biomarker testing and targeted therapy for gastric cancer.
文摘The rapid progress in the construction of heavy-haul and high-speed railways has led to a surge in rail defects and unforeseen failures.Addressing this issue necessitates the implementation of more sophisticated rail inspection methods,specifically involving real-time,precise detection,and assessment of rail defects.Current applications fail to address the evolving requirements,prompting the need for advancements.This paper provides a summary of various types of rail defects and outlines both traditional and innovative non-destructive inspection techniques,examining their fundamental features,benefits,drawbacks,and practical suitability for railway track inspection.It also explores potential enhancements to equipment and software.The comprehensive review draws upon pertinent international research and review papers.Furthermore,the paper introduces a fusion of inspection methods aimed at enhancing the overall reliability of defect detection.
文摘The purpose of this study is to analyze the application of ultrasonic non-destructive testing technology in bridge engineering.During the research phase,based on literature collection and reading,as well as the analysis of bridge inspection materials,the principle of ultrasonic non-destructive testing technology and its adaptability to bridge engineering are elaborated.Subsequently,starting from the preparation work before inspection until damage assessment,the entire process of ultrasonic non-destructive testing is studied,and finally,a technical system of ultrasonic non-destructive testing for bridge engineering that runs through the entire process is formed.It is hoped that this article can provide technical reference value for relevant units in China,and promote the high-quality development of China’s bridge engineering from a macro perspective.
基金funded by National Key R&D Program of China(Grant No.2023YFC3007001)Beijing Natural Science Foundation(Grant No.8244053)China Postdoctoral Science Foundation(Grant No.2024M754065).
文摘The mechanical behavior of cohesive soil is sensitized to drying-wetting cycles under confinements.However,the hydromechanical coupling effect has not been considered in current constitutive models.A macro-micro analysis scheme is proposed in this paper to investigate the soil deformation behavior under the coupling of stress and drying-wetting cycles.A new device is developed based on CT(computerized tomography)workstation to apply certain normal and shear stresses on a soil specimen during drying-wetting cycles.A series of tests are conducted on a type of loess with various coupling of stress paths and drying-wetting cycles.At macroscopic level,stress sensor and laser sensor are used to acquire stress and strain,respectively.The shear and volumetric strain increase during the first few drying-wetting cycles and then become stable.The increase of the shear stress level or confining pressure would cause higher increase rate and the value of shear strain in the process of drying-wetting cycles.At microscopic level,the grayscale value(GSV)of CT scanning image is characterized as the proportion of soil particles to voids.A fabric state parameter is proposed to characterize soil microstructures under the influence of stress and drying-wetting cycle.Test results indicate that the macroand micro-responses show high consistence and relevance.The stress and drying-wetting cycles would both induce collapse of the soil microstructure,which dominants degradation of the soil mechanical properties.The evolution of the macro-mechanical property of soil exhibits a positive linear relationship with the micro-evolution of the fabric state parameter.
基金supported by the“National Ocean Technology Center Innovation Fund”under Project No.N3220Z002,led by Ning Jia.The official website of the National Ocean Technology Center is accessible at:http://www.notcsoa.org.cn/.
文摘With the depletion of fossil fuels and increasing environmental concerns,the development of renewable energy,such as wave energy,has become a critical component of global energy strategies.However,challenges persist in the field testing methodologies for wave energy converters(WECs).In this paper,a numerical wave field of the Dawanshan Island Sea Area in Zhuhai City is constructed based on the MIKE21 SW wave model and by using an NCEP wind field driving model.In conjunction with the IEC-62600-100 standard,by taking site testing of the“Wanshan”wave energy converter on which a sea trial has been conducted in Dawanshan Island of Zhuhai city as an example,research on-site testing method for a wave energy converter has been carried out.The wave measurement position for the“Wanshan”converter was determined by combining statistically analyzed field data with a validated numerical wave model.By comparing a valid wave height at the position where a wave rider is located with a valid wave height at the position where the“Wanshan”wave energy converter is situated,the correlation coefficient between simulation and observed data reached 0.90,with a root-mean-square error of 0.19.The representativeness of wave measurement data during site testing is verified and can be used as a basis for calculating the input energy of the“Wanshan”wave energy converter.
基金supported by the National Natural Science Foundation of China for Distinguished Young Scholars(Grant No.42225206)National Natural Science Foundation of China(42207180,42477209,42302320).
文摘Subgrade engineering is a fundamental aspect of infrastructure construction in China.As the primary structural element responsible for bearing and distributing traffic loads,the subgrade must not only withstand the substantial pressures exerted by vehicles,trains,and other forms of transportation,but also efficiently transfer these loads to the underlying foundation,ensuring the stability and longevity of the roadway.In recent years,advancements in subgrade engineering technology have propelled the industry towards smarter,greener,and more sustainable practices,particularly in the areas of intelligent monitoring,disaster management,and innovative construction methods.This paper reviews the application and methodologies of intelligent testing equipment,including cone penetration testing(CPT)devices,soil resistivity testers,and intelligent rebound testers,in subgrade engineering.It examines the operating principles,advantages,limitations,and application ranges of these tools in subgrade testing.Additionally,the paper evaluates the practical use of advanced equipment from both domestic and international perspectives,addressing the challenges encountered by various instruments in realworld applications.These devices enable precise,comprehensive testing and evaluation of subgrade conditions at different stages,providing real-time data analysis and intelligent early warnings.This supports effective subgrade health management and maintenance.As intelligent technologies continue to evolve and integrate,these tools will increasingly enhance the accuracy,efficiency,and sustainability of subgrade monitoring.
