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Measurement of aerodynamic heating of micro-scale rotational shearing flow and its heat flux identification
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作者 Yuan LIU Yuanwei LYU +3 位作者 Jingyang ZHANG Chunyang LI Jingzhou ZHANG Zhongwen HUANG 《Chinese Journal of Aeronautics》 2025年第4期70-90,共21页
This study conducted the experimental investigation of aerodynamic heating of Micro-scale Rotational Shearing Flow with Axial Limited-Length(MRSFALL).The temperature riseof the stator is captured by the high response ... This study conducted the experimental investigation of aerodynamic heating of Micro-scale Rotational Shearing Flow with Axial Limited-Length(MRSFALL).The temperature riseof the stator is captured by the high response thermocouples.The eccentricity ratio and clearanceheight are guaranteed by means of instantaneous trajectory and torsion monitoring of the rotator.The result shows that the maximum temperature rise takes place upstream of the minimum clear-ance height along circumferential direction.The distribution of temperature rise presents asymmet-ric curve along axial direction,and peak value occurs near the dimensionless axial position of-0.18.The effect of aerodynamic heating becomes notable as the rotational speed is larger than3×10^(4)r/min.The effect of end leakage and the viscous dissipation have great impact on temper-ature rise of MRSFALL.More specially,the peak value of temperature rise at dimensionless clear-ance height of 0.0080 is larger than the case at dimensionless clearance height of 0.0044.Furthermore,when the eccentricity ratio is too large,the viscous dissipation is induced,and theadditional temperature rise is achieved.The heat flux identification of shear flow has been realizedby Sequential Function Specification Method(SFSM)and its estimation of thermal load has been given.The heat flux induced by the aerodynamic heating in this study varies from 950 W/m^(2)to1330 W/m^(2). 展开更多
关键词 micro-scale Rotational Shearing flow with Axial Limited-Length(MRSFALL) Hyper-rotate-speed End leakage Aerodynamic heating experimental measurement Heat flux identification
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Recent Advances in Computational Simulation of Macro-,Meso-,and Micro-Scale Biomimetics Related Fluid Flow Problems 被引量:5
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作者 Y. Y. Yan 《Journal of Bionic Engineering》 SCIE EI CSCD 2007年第2期97-107,共11页
Over the last decade, computational methods have been intensively applied to a variety of scientific researches and engineering designs. Although the computational fluid dynamics (CFD) method has played a dominant r... Over the last decade, computational methods have been intensively applied to a variety of scientific researches and engineering designs. Although the computational fluid dynamics (CFD) method has played a dominant role in studying and simulating transport phenomena involving fluid flow and heat and mass transfers, in recent years, other numerical methods for the simulations at meso- and micro-scales have also been actively applied to solve the physics of complex flow and fluid-interface interactions. This paper presents a review of recent advances in multi-scale computational simulation of biomimetics related fluid flow problems. The state-of-the-art numerical techniques, such as lattice Boltzmann method (LBM), molecular dynamics (MD), and conventional CFD, applied to different problems such as fish flow, electro-osmosis effect of earthworm motion, and self-cleaning hydrophobic surface, and the numerical approaches are introduced. The new challenging of modelling biomimetics problems in developing the physical conditions of self-clean hydrophobic surfaces is discussed. 展开更多
关键词 biomimetics computational simulation macro- meso- micro-scale HYDROPHOBIC SURFACES
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Unveiling micro-scale mechanisms of in-situ silicon alloying for tailoring mechanical properties in titanium alloys:Experiments and computational modeling
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作者 Sisi Tang Li Li +3 位作者 Jinlong Su Yuan Yuan Yong Han Jinglian Fan 《Journal of Materials Science & Technology》 2025年第17期150-163,共14页
Titanium-silicon(Ti-Si)alloy system shows significant potential for aerospace and automotive applications due to its superior specific strength,creep resistance,and oxidation resistance.For Si-containing Ti alloys,the... Titanium-silicon(Ti-Si)alloy system shows significant potential for aerospace and automotive applications due to its superior specific strength,creep resistance,and oxidation resistance.For Si-containing Ti alloys,the sufficient content of Si is critical for achieving these favorable performances,while excessive Si addition will result in mechanical brittleness.Herein,both physical experiments and finite element(FE)simulations are employed to investigate the micro-mechanisms of Si alloying in tailoring the mechanical properties of Ti alloys.Four typical states of Si-containing Ti alloys(solid solution state,hypoeutectoid state,near-eutectoid state,hypereutectoid state)with varying Si content(0.3-1.2 wt.%)were fabricated via in-situ alloying spark plasma sintering.Experimental results indicate that in-situ alloying of 0.6 wt.%Si enhances the alloy’s strength and ductility simultaneously due to the formation of fine and uniformly dispersed Ti_(5)Si_(3)particles,while higher content of Si(0.9 and 1.2 wt.%)results in coarser primary Ti_(5)Si_(3)agglomerations,deteriorating the ductility.FE simulations support these findings,highlighting the finer and more uniformly distributed Ti_(5)Si_(3)particles contribute to less stress concentration and promote uniform deformation across the matrix,while agglomerated Ti_(5)Si_(3)particles result in increased local stress concentrations,leading to higher chances of particle fracture and reduced ductility.This study not only elucidates the micro-mechanisms of in-situ Si alloying for tailoring the mechanical properties of Ti alloys but also aids in optimizing the design of high-performance Si-containing Ti alloys. 展开更多
关键词 Titanium alloy Spark plasma sintering micro-scale deformation behavior Mechanical property tailoring Computational modeling
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Effect of Initial Microstructure States on Flow Behavior of Al-Zn-Mg-Cu Alloy During Hot Tensile Deformation
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作者 Wang Shuyan Zhou Yuting +3 位作者 Du Ruibo Long Shuai Lin Haitao Wang Shaoyang 《稀有金属材料与工程》 北大核心 2026年第2期302-314,共13页
To investigate the influence of Al-Zn-Mg-Cu alloy with as-homogenized and as-rolled initial microstructures on the tensile flow behavior,isothermal tensile tests were conducted on a GLEEBLE-3500 isothermal simulator a... To investigate the influence of Al-Zn-Mg-Cu alloy with as-homogenized and as-rolled initial microstructures on the tensile flow behavior,isothermal tensile tests were conducted on a GLEEBLE-3500 isothermal simulator at temperatures of 380-440℃and strain rates of 0.05-1 s^(−1).The Johnson-Cook model,Hensel-Spittel model,strain-compensated Arrhenius model,and critical fracture strain model were established.Results show that through the evaluation of the models using the correlation coefficient(R)and the average absolute relative error,the strain-compensated Arrhenius model can represent the flow behavior of the alloy more accurately.Shear bands are more pronounced in the as-homogenized specimens,whereas dynamic recrystallization is predominantly observed in as-rolled specimens.Fracture morphology analysis reveals that a mixed fracture mechanism is prevalent in the as-homogenized specimen,whereas a ductile fracture mechanism is predominant in the as-rolled specimen.The processing maps indicate that the unstable region is reduced in the as-rolled specimens compared with that in the as-homogenized specimens.The optimal hot working windows for the as-homogenized and as-rolled specimens are determined as 410-440℃/0.14-1 s^(−1)and 380-400℃/0.05-0.29 s^(−1),respectively. 展开更多
关键词 Al-Zn-Mg-Cu alloy tensile flow behavior MICROSTRUCTURE constitutive modelling processing map
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Comparative studies on nanocarbon-modified carbon paper electrodes for enhanced electrocatalytic performance in vanadium redox flow batteries
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作者 Jaeho Jo Jaeeon Chang Doohwan Lee 《新型炭材料(中英文)》 北大核心 2026年第1期196-208,共13页
Vanadium redox flow batteries(VRFBs)are a means of large-scale energy storage due to their excellent scalability,safety,long cycling life,and decoupled power and energy capacities.However,the slow redox kinetics of va... Vanadium redox flow batteries(VRFBs)are a means of large-scale energy storage due to their excellent scalability,safety,long cycling life,and decoupled power and energy capacities.However,the slow redox kinetics of vanadium species on conventional carbon electrodes remains a major limitation to their performance.We investigated the deposition of carbon black,carbon nanotubes,and electrochemically exfoliated graphene(Exf-Gr)onto thermally-activated carbon paper(ACP)by spray coating to increase the electrode electrocatalytic activity.The modified electrodes were characterized using scanning electron microscopy,X-ray diffraction,Raman spectroscopy,X-ray photoelectron microscopy,and surface area analysis,while their electrochemical properties were evaluated by cyclic voltammetry,electrochemical impedance spectroscopy,and singlecell VRFB testing.Among the modified electrodes,Exf-Gr/ACP had the best performance,achieving a 2.9-fold reduction in charge transfer resistance compared to pristine ACP and delivering 2.5 times the discharge capacity in single-cell tests.This improvement is attributed to Exf-Gr’s high surface area,favorable catalytic activity,and excellent dispersion on the ACP substrate.Surface modification with electrochemically exfoliated graphene is a highly effective strategy for improving the electrode performance in VRFB systems,with significant implications for large-scale energy storage. 展开更多
关键词 Vanadium redox flow battery Carbon paper electrode Exfoliated graphene Carbon nanotube ELECTROCATALYSIS
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Influence of feature size of micro-scale channel on ink flow characteristics
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作者 初红艳 Lin Xuecong +1 位作者 Zhao Pile Cai Ligang 《High Technology Letters》 EI CAS 2018年第3期296-302,共7页
Under the micro-scale condition,feature size of the channel is one of the main factors influencing the fluid flow characteristics. In printing process,ink thickness in the extrusion zone formed by two ink rollers may ... Under the micro-scale condition,feature size of the channel is one of the main factors influencing the fluid flow characteristics. In printing process,ink thickness in the extrusion zone formed by two ink rollers may reach micron scale. Compared with macroscopic fluid,the velocity field and the pressure field of fluid may change when the feature size of fluid channel reaches micron scale. In order to control printing quality,it is necessary to research the influence of feature size on ink flow characteristics in micro scale. This paper analyzes it in theory,and then numerical simulation of an ink flow model with different feature sizes is carried out in no slip condition. The influence of the feature size on the ink flow characteristics and the wall shear force are obtained. Besides,the ink flow model with different feature sizes is simulated numerically in slip condition,and the influence of feature size on ink flow characteristics is obtained. Finally,by comparing and analyzing the above results,it can be concluded that both the ink velocity and pressure at the inlet of the extrusion zone are inversely proportional to the feature sizes whether in slip condition or not. And the ink velocity in slip condition is larger than that without slip,the pressure at the inlet of the extrusion zone is less than that in no slip condition. Within the micro-scale range,the ink velocity difference between the two conditions cannot be ignored. Therefore,it is necessary to consider slip when analyzing the influence of feature size of micro-scale channel on ink flow characteristics. 展开更多
关键词 ink flow feature size velocity slip VELOCITY PRESSURE
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Numerical investigation of mixed-phase turbulence in flow past a partially merged plate
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作者 Junqi Tong Rong Li Zixuan Yang 《Acta Mechanica Sinica》 2026年第1期3-14,共12页
Large-eddy simulation(LES)is conducted to study the statistical properties of mixed-phase turbulence induced by the breaking of bow waves in flow past a partially submerged plate.The simulation is performed using a fi... Large-eddy simulation(LES)is conducted to study the statistical properties of mixed-phase turbulence induced by the breaking of bow waves in flow past a partially submerged plate.The simulation is performed using a finite difference method,with the air-water interface captured by a coupled level-set and volume-of-fluid method.Four cases are conducted to investigate the effects of Froude number on turbulent statistics,including the mean velocity,turbulence kinetic energy,and turbulence mass flux(TMF),which is an additional unclosed term in the Reynolds-averaged momentum equation.The TMF,especially its vertical component,shows a complex behaviour with respect to the Froude number.This property of the TMF imposes high demands on the robustness of the closure model of TMF.The present LES data is further used to examine a closure model of the TMF production term,which shows a high correlation with the data obtained from LES. 展开更多
关键词 Turbulent flows Multiphase flows Wave breaking
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Multi-relaxation-time lattice Boltzmann simulation of slide damping in micro-scale shear-driven rarefied gas flow
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作者 Song Xucheng Li Pu Zhu Rui 《Journal of Southeast University(English Edition)》 EI CAS 2019年第1期30-35,共6页
To investigate the slide film damping in the micro-scale shear-driven rarefied gas flows, an effective multi-relaxation-time lattice Boltzmann method(MRT-LBM) is proposed. Through the Knudsen boundary layer model, the... To investigate the slide film damping in the micro-scale shear-driven rarefied gas flows, an effective multi-relaxation-time lattice Boltzmann method(MRT-LBM) is proposed. Through the Knudsen boundary layer model, the effects of wall and rarefaction are considered in the correction of relaxation time. The results of gas velocity distributions are compared among the MRT, Monte Carlo model(DSMC) and high-order LBM, and the effects of the tangential momentum accommodation coefficient on the gas velocity distributions are also compared between the MRT and the high-order LBM. It is indicated that the amendatory MRT-LBM can unlock the dilemma of simulation of micro-scale non-equilibrium. Finally, the effects of the Knudsen number, the Stokes number, and the gap between the plates on the damping are researched. The results show that by decreasing the Knudsen number or increasing the Stokes number, the slide film damping increases in the transition regime;however, as the size of the gap increases, the slide film damping decreases substantially. 展开更多
关键词 lattice Boltzmann method multi-relaxation-time slide film damping shear-driven oscillating flow
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基于SolidWorks Flow Simulation的调节阀流场模拟与固有流量特性研究
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作者 李庆 范文瀚 《阀门》 2026年第2期212-218,共7页
调节阀开度与流量特性直接影响工业过程的控制精度,流量系数C_(v)是评价其流通性能的核心指标。以DN100、CL150、可调比R=50的单座调节阀为对象,采用SolidWorks Flow Simulation构建三维流场模型,对10%~100%开度区间的阀门开展数值模拟... 调节阀开度与流量特性直接影响工业过程的控制精度,流量系数C_(v)是评价其流通性能的核心指标。以DN100、CL150、可调比R=50的单座调节阀为对象,采用SolidWorks Flow Simulation构建三维流场模型,对10%~100%开度区间的阀门开展数值模拟,通过模型简化、节流区网格加密与规范边界条件获取速度场、压力场分布;网格独立性验证表明,中等密度网格的C_(v)计算偏差小于3%,满足工程精度。恒定压差下提取各开度下的稳态流量并计算C_(v),结果显示C_(v)呈等百分比增长,小开度增长平缓、中大开度增速加快,与节流机理一致;仿真结果与R=50理论等百分比曲线在多数开度区间吻合,验证了方法的可靠性。该仿真方法为调节阀设计优化、流量特性预测与性能评估提供了有效支撑。 展开更多
关键词 单座调节阀 流量系数C_(v) CFD数值模拟 等百分比特性 SolidWorks flow Simulation
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Multiscale Single-Phase Flow Mechanisms of Shale Oil Revealed by High-Pressure Nuclear Magnetic Resonance Experiments
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作者 Maolei Cui Zengmin Lun +2 位作者 Jie Zhang Jun Niu Pufu Xiao 《Fluid Dynamics & Materials Processing》 2026年第2期253-264,共12页
To clarify fluid flow mechanisms and establish effective development conditions in continental shale oil reservoirs,a high-temperature,high-pressure steady-state flow system integrated with nuclear magnetic resonance(... To clarify fluid flow mechanisms and establish effective development conditions in continental shale oil reservoirs,a high-temperature,high-pressure steady-state flow system integrated with nuclear magnetic resonance(NMR)technology has been developed.The apparatus combines sample evacuation,rapid pressurization and saturation,and controlled displacement,enabling systematic investigation of single-phase shale oil flow under representative reservoir conditions.Related experiments allow proper quantification of the activation thresholds and relative contributions of different pore types to flow.A movable fluid index(MFI),defined using dual T_(2) cutoff values,is introduced accordingly and linked to key flow parameters.The results reveal distinct multi-scale characteristics of single-phase shale oil transport,namely micro-scale graded displacement and macro-scale segmented nonlinear behavior.As the injection-production pressure difference increases,flow pathways are activated progressively,beginning with fractures,followed by large and then smaller macropores,leading to a pronounced enhancement in apparent permeability.Although mesopores and micropores contribute little to direct flow,their indirect influence becomes increasingly important,and apparent permeability gradually approaches a stable limit at higher pressure difference.It is also shown that the MFI exhibits a strong negative correlation with the starting pressure gradient and a positive correlation with apparent permeability,providing a rapid and reliable indicator of shale oil flow capacity.Samples containing through-going fractures display consistently higher MFI values and superior flowability compared with those dominated by laminated fractures,highlighting the pivotal role of well-connected fracture networks generated by large-scale hydraulic fracturing in improving shale oil production. 展开更多
关键词 Shale oil laminated fractures steady-state flow Nuclear Magnetic Resonance(NMR) nonlinear flow
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Characteristics of wind-sand flow in longitudinal slope embankment section of desert highway
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作者 LI Liangying ZHANG Yu +3 位作者 XIN Guowei WANG Zhenqiang JI Shuai WANG Xu 《Journal of Mountain Science》 2026年第1期270-281,共12页
Investigating the wind-sand flow response regularity in the longitudinal slope sections of desert highways provides a scientific basis for selecting the slope of desert roads.This study uses the Tengger Desert section... Investigating the wind-sand flow response regularity in the longitudinal slope sections of desert highways provides a scientific basis for selecting the slope of desert roads.This study uses the Tengger Desert section of the Wuhai-Maqin Expressway as a case study,employing CFD numerical simulation methods to calculate and analyze the wind-sand flow field distribution characteristics in different longitudinal slope sections.The results show that:(1)Along with the direction of the incoming flow,the windward and leeward slope toes of the embankment are low-wind-speed zones,with the wind speed at the leeward slope toe being even lower.The higher the embankment,the larger the low-wind-speed zone at the windward and leeward slope toes.As the longitudinal slope increases,the extent of the lowwind-speed zone at the same location along the route also increases.(2)Along the route direction,the wind speed at the windward and leeward slope toes decreases as embankment height increases.At the embankment toe,sand particles are transported from the top to the bottom of the longitudinal slope,and the greater the longitudinal slope,the stronger the transport effect.(3)Along the route direction,the sand accumulation around the embankment gradually gathers toward the bottom of the longitudinal slope as the slope increases.When the longitudinal slope is 3%and 4%,the trend of sand accumulation moving from the windward side at the end of the route to the leeward side at the start of the route is more significant.When the longitudinal slope is less than or equal to 3%,severe sand accumulation within the embankment range is reduced by 86.4%or more compared to when the slope is 4%.(4)Under the same longitudinal slope,the higher the embankment height,the smaller its transport rate.When the embankment height is the same,the greater the longitudinal slope,the greater the embankment transport rate. 展开更多
关键词 Desert highway Wind-sand flow Longitudinal slope gradient flow field structure Sand accumulation law Numerical simulation
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Non-Newtonian rivulet flows on an inclined planar surface applying the 2nd Stokes problem
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作者 S.V.ERSHKOV E.S.BARANOVSKII A.V.YUDIN 《Applied Mathematics and Mechanics(English Edition)》 2026年第1期153-164,共12页
The newly formulated non-Newtonian rivulet flows streaming down an inclined planar surface,with additional periodic perturbations arising from the application of the 2nd Stokes problem to the investigation of rivulet ... The newly formulated non-Newtonian rivulet flows streaming down an inclined planar surface,with additional periodic perturbations arising from the application of the 2nd Stokes problem to the investigation of rivulet dynamics,are demonstrated in the current research.Hereby,the 2nd Stokes problem assumes that the surface,with a thin shared layer of the fluid on it,oscillates in a harmonic manner along the x-axis of the rivulet flow,which coincides with the main flow direction streaming down the underlying surface.We obtain the exact extension of the rivulet flow family,clarifying the structure of the pressure field,which fully absorbs the arising perturbation.The profile of the velocity field is assumed to be Gaussian-type with a non-zero level of plasticity.Hence,the absolutely non-Newtonian case of the viscoplastic flow solution,which satisfies the motion and continuity equations,is considered(with particular cases of exact solutions for pressure).The perturbed governing equations of motion for rivulet flows then result in the Riccati-type ordinary differential equation(ODE),describing the dynamics of the coordinate x(t).The approximated schematic dynamics are presented in graphical plots. 展开更多
关键词 rivulet flow non-Newtonian fluid creeping viscoplastic flow 1st/2nd Stokes problem
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Editorial:Computational simulations of particle-/drop-laden flows
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作者 Xiang Yang S.Balachandar +1 位作者 Robert Kunz Zixuan Yang 《Acta Mechanica Sinica》 2026年第1期1-2,共2页
Particle-and droplet-laden flows are central to many problems in mechanics and transport.They occur in sedimentladen boundary layers,gas-solid and gas-liquid dispersions,and surface-water films driven by external forc... Particle-and droplet-laden flows are central to many problems in mechanics and transport.They occur in sedimentladen boundary layers,gas-solid and gas-liquid dispersions,and surface-water films driven by external forcing.They also underpin practical applications ranging from environmental transport to high-speed and aerothermal systems.Despite decades of progress,prediction remains difficult.The physics spans a wide range of scales and often couples turbulence,interphase momentum exchange,collisions,and interfacial transport.Reliable computation therefore requires both robust numerical methodology and careful physical interpretation. 展开更多
关键词 COLLISIONS particle laden flows interphase momentum exchange sedimentladen boundary layersgas solid practical applications environmental transport turbulence drop laden flows
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Studies of directed flow with event plane method in the HIRFL-CSR external-target experiment
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作者 Wan-Long Wu Xiong-Hong He +3 位作者 Yan-Yu Ren Di-Yu Shen Shu-Su Shi Xu Sun 《Nuclear Science and Techniques》 2026年第4期19-27,共9页
The Cooling-Storage-Ring External-target Experiment(CEE)at the Heavy Ion Research Facility in Lanzhou(HIRFL)is designed to study the properties of nuclear matter created in heavy-ion collisions at beam energies from a... The Cooling-Storage-Ring External-target Experiment(CEE)at the Heavy Ion Research Facility in Lanzhou(HIRFL)is designed to study the properties of nuclear matter created in heavy-ion collisions at beam energies from a few hundred MeV/u up to 1 GeV/u.It aims to facilitate research on the quantum chromodynamics(QCD)phase structure in the high-baryondensity region.Collective flow is a fundamental observable in heavy-ion collision experiments,providing information on the bulk properties of the produced matter.Although the standard event plane method has been widely used to measure collective flow,it is still important to validate and optimize this method for the CEE spectrometer.In this paper,we study the experimental procedures for measuring directed flow in^(238)U+^(238)U collisions at 500 MeV/u,using event planes reconstructed by Multi-Wire Drift Chamber and Zero Degree Calorimeter,respectively.Jet AA Microscopic(JAM)transport generator is used to generate events,and the detector response is simulated by the CEE Fast Simulation(CFS)package.Finally,the optimal kinematic region for proton directed flow measurements is discussed for the future CEE experiment. 展开更多
关键词 Heavy-ion collisions CEE Directed flow Event plane
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Stability of k-ε model in Kolmogorov flow
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作者 Jiashuo GUO Le FANG 《Applied Mathematics and Mechanics(English Edition)》 2026年第1期165-184,共20页
The Reynolds-averaged Navier-Stokes(RANS)technique enables critical engineering predictions and is widely adopted.However,since this iterative computation relies on the fixed-point iteration,it may converge to unexpec... The Reynolds-averaged Navier-Stokes(RANS)technique enables critical engineering predictions and is widely adopted.However,since this iterative computation relies on the fixed-point iteration,it may converge to unexpected non-physical phase points in practice.We conduct an analysis on the phase-space characteristics and the fixed-point theory underlying the k-ε turbulence model,and employ the classical Kolmogorov flow as a framework,leveraging its direct numerical simulation(DNS)data to construct a one-dimensional(1D)system under periodic/fixed boundary conditions.The RANS results demonstrate that under periodic boundary conditions,the k-ε model exhibits only a unique trivial fixed point,with asymptotes capturing the phase portraits.The stability of this trivial fixed point is determined by a mathematically derived stability phase diagram,indicating the fact that the k-ε model will never converge to correct values under periodic conditions.In contrast,under fixed boundary conditions,the model can yield a stable non-trivial fixed point.The evolutionary mechanisms and their relationship with boundary condition settings systematically explain the inherent limitations of the k-ε model,i.e.,its deficiency in computing the flow field under periodic boundary conditions and sensitivity to boundary-value specifications under fixed boundary conditions.These conclusions are finally validated with the open-source code OpenFOAM. 展开更多
关键词 k-εmodel Kolmogorov flow INSTABILITY turbulence model
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4D Flow CMR评估AMI患者左室血流组分与左室功能的相关性研究
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作者 王少喆 李炎 +7 位作者 李国策 潘志斌 边浩 张磊 张厚宁 康立清 张斌 刘凤海 《磁共振成像》 北大核心 2026年第2期73-79,共7页
目的探讨基于四维血流心脏磁共振(four-dimensional flow cardiac magnetic resonance,4D Flow CMR)成像技术的左室血流组分在急性心肌梗死(acute myocardial infarction,AMI)患者左心室血流动力学评估中的应用价值。材料与方法回顾性分... 目的探讨基于四维血流心脏磁共振(four-dimensional flow cardiac magnetic resonance,4D Flow CMR)成像技术的左室血流组分在急性心肌梗死(acute myocardial infarction,AMI)患者左心室血流动力学评估中的应用价值。材料与方法回顾性分析62例AMI患者(AMI组),根据左心室射血分数(left ventricular ejection fraction,LVEF)分为LVEF受损组(34例)及LVEF保留组(28例),另纳入同期就诊的年龄性别基本匹配的25例对照受试者。所有受试者均收集临床资料及心脏磁共振(cardiac magnetic resonance,CMR)数据,包括常规心功能参数、左心室(left ventricular,LV)功能性血流成分[直接血流(direct flow,DF)、保留流入量(retained inflow,RIF)、延迟射血流量(delayed ejection flow,DEF)、剩余量(residual volume,RV)]比例及动能(kinetic energy,KE)值,比较组间差异性。结果AMI组的四个血流分量比例与对照组差异均具有统计学意义(均P<0.05),具体为DF[(27.4±12.4)%vs.(38.4±6.2)%],RIF[(17.4±4.6)%vs.(15.1±4.3)%],DEF[(20.9±5.0)%vs.(16.5±3.8)%],RV[(33.9±9.2)%vs.(30.0±5.9)%]。LVEF受损组与LVEF保留组的LVEF和四个血流分量比例差异均有统计学意义,分别为LVEF[(37.5±10.4)%vs.(60.6±7.8)%,P<0.001],DF[(22.4±9.9)%vs.(33.4±12.6)%,P<0.001],RIF[(18.5±3.9)%vs.(16.2±5.2)%,P=0.048],DEF[(22.7±4.6)%vs.(18.7±4.5)%,P=0.001],RV[(36.1±10.3)%vs.(31.2±7.0)%,P=0.034]。与对照组相比,LVEF保留组DF比例减少,DEF比例增多,差异有统计学意义(P=0.046,P=0.014)。AMI组的DF收缩期峰值及平均KE均显著低于对照组[25(20,31)vs.38(31,45)µJ/mL],[12(9,18)vs.18(15,22)µJ/mL],均P<0.001。AMI组左心室每搏输出量(left ventricular stroke volume,LVSV)与DF比例的相关性较对照组减弱(r=0.668,r=0.375),两组其余血流组分与LVSV均无显著相关性(均P>0.05)。结论4D Flow CMR技术衍生的左室血流组分参数对AMI后左室血流动力学评估具有较高的价值,可辅助临床评估AMI后的左心室功能,并为识别AMI后具有潜在风险的患者提供线索。 展开更多
关键词 急性心肌梗死 磁共振成像 四维血流心脏磁共振成像 血流组分 血流动力学 左室功能
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Influence of Multiple Electromagnetic Sources for Heat Transfer Improvement of Ferrofluid Flow inside the Serpentine Tube:A Computational Study
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作者 M.Barzegar Gerdroodbary S.Valiallah Mousavi Seyyed Amirreza Abdollahi 《Computer Modeling in Engineering & Sciences》 2026年第2期624-641,共18页
This study investigates the enhancement of convective heat transfer in a serpentine pipe using ferrofluid flow influenced by dual non-uniform magnetic sources.The primary objective is to improve thermal performance in... This study investigates the enhancement of convective heat transfer in a serpentine pipe using ferrofluid flow influenced by dual non-uniform magnetic sources.The primary objective is to improve thermal performance in compact cooling systems,such as those used in heat exchangers.A two-dimensional,steady-state Computational Fluid Dynamic(CFD)model is developed in ANSYS Fluent to simulate the behavior of an incompressible ferrofluid under applied constant heat flux and magnetic fields.The magnetic force is modeled using the Kelvin force,which acts on magnetized nanoparticles in response to spatially varying electromagnetic fields generated by two strategically positioned current-carrying wires.The effects of magnetic field strength,quantified by the magnetic number(Mn),on flow behavior and temperature distribution are thoroughly analyzed.The results indicate that increasing Mn leads to higher Nusselt numbers,demonstrating enhanced convective heat transfer.Secondary vortices induced by magnetic forcing improve fluid mixing,particularly in curved regions of the pipe.A mesh-independence study and model validation with benchmark data support the reliability of the numerical framework.This work highlights the potential of magnetic-field-assisted thermal control in energy-efficient cooling applications and provides a foundation for the further development of advanced ferrofluid-based heat transfer systems. 展开更多
关键词 Ferrofluid flow heat transfer CFD serpentine pipe heat exchangers
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Quantitative laser speckle blood flow imaging using event cameras
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作者 Zeren GAO Tongxin LIAO +2 位作者 Shangquan WU Chao LI Yu FU 《Science China(Technological Sciences)》 2026年第3期383-393,共11页
Vascular abnormalities are closely associated with the pathogenesis and progression of numerous diseases, such as thrombosis, tumors, and diabetes. Blood flow velocity serves as a critical biomarker for evaluating per... Vascular abnormalities are closely associated with the pathogenesis and progression of numerous diseases, such as thrombosis, tumors, and diabetes. Blood flow velocity serves as a critical biomarker for evaluating perfusion status. Quantitative detection of full-field blood flow variations in lesion areas holds significant scientific and clinical value for pathological studies,diagnosis, and intraoperative monitoring of related diseases. While laser speckle contrast imaging(LSCI) enables full-field blood flow visualization, its reliance on frame-based sensors necessitates handling massive data volumes, leading to inherent trade-offs among spatiotemporal resolution, real-time performance, and quantitative capabilities. Leveraging the asynchronous dynamic sensing, high temporal sampling rate, and low data redundancy of event cameras, this study proposes a quantitative blood flow imaging method termed laser speckle event imaging(LSEI). Experiments using off-the-shelf event cameras demonstrate that LSEI achieves real-time blood flow imaging with minimal computational overhead compared to frame-based LSCI. Furthermore,we investigate the relationship between event data streams and flow velocity through spatial-temporal autocorrelation analysis,enabling quantitative measurements without compromising temporal or spatial resolution. In in vivo imaging experiments of mouse ear blood flow, LSEI exhibits superior imaging details and real-time performance over conventional methods. The proposed approach holds promise as an efficient tool for diagnosis, therapeutic evaluation, and research on vascular-related diseases. 展开更多
关键词 blood flow imaging laser speckle imaging event cameras
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Batch and continuous-flow asymmetric synthesis of d-pantothenic acid precursor enabled by immobilized ketoreductase mutant
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作者 Pan Hu Xiaofan Wu +6 位作者 Yi An Xianjing Zheng Liang Gao Yuan Tao Yajiao Zhang Zedu Huang Fener Chen 《Chinese Chemical Letters》 2026年第2期471-476,共6页
We report an immobilized enzyme-catalyzed batch and continuous-flow synthesis of optically pure ethyl(R)-pantothenate((R)-PaOEt),the direct precursor of d-pantothenic acid.Firstly,a ketoreductase mutant designated as ... We report an immobilized enzyme-catalyzed batch and continuous-flow synthesis of optically pure ethyl(R)-pantothenate((R)-PaOEt),the direct precursor of d-pantothenic acid.Firstly,a ketoreductase mutant designated as M2,carrying two-point mutations of F97L and M242F relative to the wild-type SSCR,was constructed by site-directed mutagenesis,exhibited simultaneously improved activity toward ethyl 2′-ketopantothenate(K-PaOEt)and isopropanol,and could effectively catalyze the stereoselective reduction of K-PaOEt to(R)-PaOEt by using isopropanol as the sacrificial co-substrate to regenerate NADPH.After screening six commercially available carriers,an amino resin LXTE-700 was identified as the best solid support for the immobilization of M2 via the glutaraldehyde activation method.Upon optimization of the immobilization process and reaction conditions,the fabricated immobilized enzyme M2@amino resin demonstrated excellent recyclability and reusability,with the complete conversion of K-PaOEt to(R)-PaOEt being still realized after 12 cycles of reuse.Finally,M2@amino resin-catalyzed synthesis of(R)-PaOEt was successfully implemented in continuous-flow,accomplishing a 6.3 times higher space-time yield than that with the batch synthesis(529.2 versus 84 g L^(-1) d^(-1)).Our developed flow biocatalysis system also features an outstanding operational stability,as evidenced by the 100%conversion rate achieved after 15 consecutive days of operation. 展开更多
关键词 Asymmetric synthesis Continuous flow synthesis Enzyme immobilization KETOREDUCTASE D-Pantothenic acid
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Heat flow as a catalyst for radiogenic helium release in the East Africa Rift System
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作者 Ernest Mulaya Jon Gluyas +2 位作者 Ken McCaff rey David Byrne Chris Ballentine 《Acta Geochimica》 2026年第1期65-85,共21页
The Rukwa Rift section of the East Africa Rift System presents a type setting for radiogenic helium accumulation in a petroleum free basin.As a prerequisite for accumulation,a considerable high heat flow anomaly is re... The Rukwa Rift section of the East Africa Rift System presents a type setting for radiogenic helium accumulation in a petroleum free basin.As a prerequisite for accumulation,a considerable high heat flow anomaly is required from tectonothermal events to drive the release and circulation of radiogenic helium in the continental crust.Here we apply statistical analysis on geochemical data observed in thermal springs and recorded heat flow to account for crustal helium mass balance for each tectonothermal event in the region.Our results demonstrate anomalously high heat flow~64-99 mW/m^(2) with a consistent trend of helium isotopic ratio and fluid chemistry in the Rukwa Rift.Mass balance calculation show that the whole crustal volume underlying the East Africa Helium Pool(EAHP)has a capability of producing radiogenic helium of about 9.9×10^(6) mol/yr(22×10^(-6) mol 4He/m^(2) yr)while the total radiogenic helium flux ranges between~2.39×10^(6) mol/yr and~2.68×10^(9) mol/yr.The Tanzania Craton contributes largely to radiogenic helium releasing up to 50% of the total capacity in the region.The total ^(4)He emission in the Rukwa Rift Basin is about 4.45×10^(5)-5.01×10^(8) mol/yr which is thus equivalent to 19%-21% of the total production capacity in the region.These results imply that the helium accumulation in the EAHP would have started as early as Paleoproterozoic(2.349 Ga).These results provide a qualitative and quantitative insight to assess both helium and geothermal potentiality in the region. 展开更多
关键词 Radiogenic helium Rukwa Rift Heat flow Helium potential Helium concentration
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