To investigate a contribution of O-methylguanineto mutagenesis in mouse cells,we constructed ashuttle vector plasmid,pYZ289,from a part ofpZ189 plasmid and polyoma virus DNA.The plasmidcontains a supF gene as a marker...To investigate a contribution of O-methylguanineto mutagenesis in mouse cells,we constructed ashuttle vector plasmid,pYZ289,from a part ofpZ189 plasmid and polyoma virus DNA.The plasmidcontains a supF gene as a marker of mutation andcan replicate in both E.coli and mouse cells.ThepYZ289 treated with N-methyl-N-nitrosourea (MNU)展开更多
In this study the sperm morphology assay of Wyrobek andco-workers was adapted and expanded to assesstris-(2-methy1-1-aziridinyl) phosphine oxide (MAPO) relatedtesticular toxicity.The aim was to allow detection of
As one of the ways of tackling the energy problem, scientists all over the world have developed many active research programs in the photolysis of water to give hydrogen gas. It has been demonstrated that sensitized p...As one of the ways of tackling the energy problem, scientists all over the world have developed many active research programs in the photolysis of water to give hydrogen gas. It has been demonstrated that sensitized photoreduction of methyl viologen (MV2+) yields MV+, the cation radical which, upon the catalytic action of colloidal platinum or hydrogenase, can reduce water to molecular hydrogen,展开更多
Objective: To explore the effects of methylprednisone on induction of apotosis and expression of interleukin-1 B converting enzyme in the kidneys. Methods: We investigated the effects of MPS on
The need for sustainable fuels has resulted in the production of renewables from a wide range of sources,in particular organic fats and oils.The use of biofuel is becoming more widespread as a result of environmental ...The need for sustainable fuels has resulted in the production of renewables from a wide range of sources,in particular organic fats and oils.The use of biofuel is becoming more widespread as a result of environmental and economic considerations.Several efforts have been made to substitute fossil fuels with green fuels.Ester molecules extracted from processed animal fats and organic plant materials are considered alternatives for the use in modern engine technologies.Two different methods have been adopted for converting esters in vegetable oils/animal fats into compounds consistent with petroleum products,namely the transesterification and the hydro-processing of ester bonds for the production of biodiesel.This review paper primarily focuses on conventional and renewable biodiesel feedstocks,the catalyst used and reaction kinetics of the production process.展开更多
24 0rganophosphates(0PPs) were tested by Salmonella test(SAL),B.subtilis DNA repair test(SUB),mouse micronucleustest(MNT-M),CHL cell micronucleus test(MNT-C) and SOSinduction test(S0S).The results of 33 0PPs in SCE te...24 0rganophosphates(0PPs) were tested by Salmonella test(SAL),B.subtilis DNA repair test(SUB),mouse micronucleustest(MNT-M),CHL cell micronucleus test(MNT-C) and SOSinduction test(S0S).The results of 33 0PPs in SCE test invitro from literatures were also analysed.The results werecontradicted to those reported by Fahrig and Klopman,thatis not only the methyl-0PPs shown genetic activity or highprobability of positive reaction,but the ethyl-0PPs in pre-sent studies,also demostrated high positive reaction rate.展开更多
With the Unscheduied DNA Synthesls (UDS),We studiedorganotropism of DNA damage in different organ cells ofrat induced by Alternariol (AOH) and Alternariol mono-methyl ether (AME) produced by Alternaria alternata thatw...With the Unscheduied DNA Synthesls (UDS),We studiedorganotropism of DNA damage in different organ cells ofrat induced by Alternariol (AOH) and Alternariol mono-methyl ether (AME) produced by Alternaria alternata thatwas preponderate strain isolated from the grain in thehigh incidence area of esophageal cancer.The展开更多
The methods of in vitro and in vivo-in vitro combinationassay for autoradiographic detection of unscheduled DNAsynthesis(UDS)induced by chemical carcinogens wasestablished.To estimate the reliability of these assays,U...The methods of in vitro and in vivo-in vitro combinationassay for autoradiographic detection of unscheduled DNAsynthesis(UDS)induced by chemical carcinogens wasestablished.To estimate the reliability of these assays,UDS in tissues slices was measured with the establishedmethods after exposure to MNNG and dimethylnitrosamine(DMN)in vitro or in vivo respectively.To study thesusceptibility of various tissues to chemicals,UDS展开更多
The aliphatic fraction of Shuicheng boghead is characterized by the mixed source inputs of microbes and higher plants. The products of microbial source inputs, i. e. C21- n-alkanes. tricyclic terpanes, steranes, singl...The aliphatic fraction of Shuicheng boghead is characterized by the mixed source inputs of microbes and higher plants. The products of microbial source inputs, i. e. C21- n-alkanes. tricyclic terpanes, steranes, single-methyl branched alkanes, isoprenoid alkanes except phytane series, drimane series, tetracyclic terpanes and hopane type of triterpanes, amount to 52.4% of the aliphatic fraction, while hydrocarbons of higher plant source input, including C22+ alkanes and some sesquiterpenoids, account for 32.2%. In addition, the phytane series of photoautotrophic chlorophyll source input just make up 7.0% of the fraction.展开更多
In a continuous effort to pursue the generality on the relationship between photoreaction mechanism and molecular orbital overlap of ground chromophores, a molecule of particular interest is 3-methyl-3-biphenylyl-1-bu...In a continuous effort to pursue the generality on the relationship between photoreaction mechanism and molecular orbital overlap of ground chromophores, a molecule of particular interest is 3-methyl-3-biphenylyl-1-butene, 1, due to the presence of excitation energy gap of 74 kcal/mol, which might make the MO overlap channel of chromophores more efficient.展开更多
Since Jacob and Monod proposed the operon model, a great quantity of data on the transcriptional control of gene expression have been accumulated. On the contrary, evidence for the translational control is relatively ...Since Jacob and Monod proposed the operon model, a great quantity of data on the transcriptional control of gene expression have been accumulated. On the contrary, evidence for the translational control is relatively less. Examples of this type of regulation include the expression of RNA phage genes and that of ribosomal protein genes展开更多
Schizandrin C (Wuweizisu C) is a new component isolated from Schizandra chinensis Baill in our Institute. Pharmacological studies show that it is capable of lowering the elevated SGPT level and also possesses a sedati...Schizandrin C (Wuweizisu C) is a new component isolated from Schizandra chinensis Baill in our Institute. Pharmacological studies show that it is capable of lowering the elevated SGPT level and also possesses a sedative effect on CNS. Structure la was at first assigned to展开更多
文摘To investigate a contribution of O-methylguanineto mutagenesis in mouse cells,we constructed ashuttle vector plasmid,pYZ289,from a part ofpZ189 plasmid and polyoma virus DNA.The plasmidcontains a supF gene as a marker of mutation andcan replicate in both E.coli and mouse cells.ThepYZ289 treated with N-methyl-N-nitrosourea (MNU)
文摘In this study the sperm morphology assay of Wyrobek andco-workers was adapted and expanded to assesstris-(2-methy1-1-aziridinyl) phosphine oxide (MAPO) relatedtesticular toxicity.The aim was to allow detection of
文摘As one of the ways of tackling the energy problem, scientists all over the world have developed many active research programs in the photolysis of water to give hydrogen gas. It has been demonstrated that sensitized photoreduction of methyl viologen (MV2+) yields MV+, the cation radical which, upon the catalytic action of colloidal platinum or hydrogenase, can reduce water to molecular hydrogen,
文摘Objective: To explore the effects of methylprednisone on induction of apotosis and expression of interleukin-1 B converting enzyme in the kidneys. Methods: We investigated the effects of MPS on
文摘The need for sustainable fuels has resulted in the production of renewables from a wide range of sources,in particular organic fats and oils.The use of biofuel is becoming more widespread as a result of environmental and economic considerations.Several efforts have been made to substitute fossil fuels with green fuels.Ester molecules extracted from processed animal fats and organic plant materials are considered alternatives for the use in modern engine technologies.Two different methods have been adopted for converting esters in vegetable oils/animal fats into compounds consistent with petroleum products,namely the transesterification and the hydro-processing of ester bonds for the production of biodiesel.This review paper primarily focuses on conventional and renewable biodiesel feedstocks,the catalyst used and reaction kinetics of the production process.
文摘24 0rganophosphates(0PPs) were tested by Salmonella test(SAL),B.subtilis DNA repair test(SUB),mouse micronucleustest(MNT-M),CHL cell micronucleus test(MNT-C) and SOSinduction test(S0S).The results of 33 0PPs in SCE test invitro from literatures were also analysed.The results werecontradicted to those reported by Fahrig and Klopman,thatis not only the methyl-0PPs shown genetic activity or highprobability of positive reaction,but the ethyl-0PPs in pre-sent studies,also demostrated high positive reaction rate.
文摘With the Unscheduied DNA Synthesls (UDS),We studiedorganotropism of DNA damage in different organ cells ofrat induced by Alternariol (AOH) and Alternariol mono-methyl ether (AME) produced by Alternaria alternata thatwas preponderate strain isolated from the grain in thehigh incidence area of esophageal cancer.The
文摘The methods of in vitro and in vivo-in vitro combinationassay for autoradiographic detection of unscheduled DNAsynthesis(UDS)induced by chemical carcinogens wasestablished.To estimate the reliability of these assays,UDS in tissues slices was measured with the establishedmethods after exposure to MNNG and dimethylnitrosamine(DMN)in vitro or in vivo respectively.To study thesusceptibility of various tissues to chemicals,UDS
基金Project supported by the National Organic Geochemistry Key Laboratory, Chinese Academy of Sciences, Guangzhou.
文摘The aliphatic fraction of Shuicheng boghead is characterized by the mixed source inputs of microbes and higher plants. The products of microbial source inputs, i. e. C21- n-alkanes. tricyclic terpanes, steranes, single-methyl branched alkanes, isoprenoid alkanes except phytane series, drimane series, tetracyclic terpanes and hopane type of triterpanes, amount to 52.4% of the aliphatic fraction, while hydrocarbons of higher plant source input, including C22+ alkanes and some sesquiterpenoids, account for 32.2%. In addition, the phytane series of photoautotrophic chlorophyll source input just make up 7.0% of the fraction.
文摘In a continuous effort to pursue the generality on the relationship between photoreaction mechanism and molecular orbital overlap of ground chromophores, a molecule of particular interest is 3-methyl-3-biphenylyl-1-butene, 1, due to the presence of excitation energy gap of 74 kcal/mol, which might make the MO overlap channel of chromophores more efficient.
文摘Since Jacob and Monod proposed the operon model, a great quantity of data on the transcriptional control of gene expression have been accumulated. On the contrary, evidence for the translational control is relatively less. Examples of this type of regulation include the expression of RNA phage genes and that of ribosomal protein genes
文摘Schizandrin C (Wuweizisu C) is a new component isolated from Schizandra chinensis Baill in our Institute. Pharmacological studies show that it is capable of lowering the elevated SGPT level and also possesses a sedative effect on CNS. Structure la was at first assigned to
