Introduction:Cardiovascular disease(CVD)has emerged as a critical determinant of prognosis and quality of life among individuals living with human immunodeficiency virus(HIV).The primary objective of this study is to ...Introduction:Cardiovascular disease(CVD)has emerged as a critical determinant of prognosis and quality of life among individuals living with human immunodeficiency virus(HIV).The primary objective of this study is to assess the CVD risk among HIVinfected individuals and determine the proportion of high-risk individuals using multiple evaluation methods.Methods:A cross-sectional study was conducted among HIV-infected individuals aged 18 years and older who were receiving antiretroviral therapy between April 26,2023,and December 16,2023.Participants were categorized into low-risk,intermediate-risk,and high-risk groups for CVD based on six risk assessment tools.Results:Our analysis revealed that the 5-year overall CVD risk estimates ranged from 2.37%to 2.50%,while the 10-year overall risk estimates spanned from 3.42%to 18.35%,with significant variations observed between subgroups.The proportion of high-risk individuals in the 10-year risk assessment,identified using five different tools,ranged from 7.85%to 31.94%,demonstrating moderate consistency across tools.Conclusions:The findings underscore the importance of closely monitoring and managing CVD risk in HIV-infected individuals.Given the variability in risk stratification methods,it is imperative to develop an assessment model tailored to the specific characteristics of the Chinese population.展开更多
基金Supported by the Shanghai Hospital Development Center(grant number SHDC22024317)Shanghai’s Three-Year Action Plan for Strengthening Public Health System Construction(2023-2025)—Building a Precision Integrated Prevention and Control Model for Major Chronic Infectious Diseases Such as Tuberculosis and AIDS(grant number GWVI-9)+1 种基金Science and Technology Commission of Shanghai Municipality(grant numbers 20MC1920100 and 21Y31900400)and Shanghai Municipal Science and Technology Major Project(grant number ZD2021CY001).
文摘Introduction:Cardiovascular disease(CVD)has emerged as a critical determinant of prognosis and quality of life among individuals living with human immunodeficiency virus(HIV).The primary objective of this study is to assess the CVD risk among HIVinfected individuals and determine the proportion of high-risk individuals using multiple evaluation methods.Methods:A cross-sectional study was conducted among HIV-infected individuals aged 18 years and older who were receiving antiretroviral therapy between April 26,2023,and December 16,2023.Participants were categorized into low-risk,intermediate-risk,and high-risk groups for CVD based on six risk assessment tools.Results:Our analysis revealed that the 5-year overall CVD risk estimates ranged from 2.37%to 2.50%,while the 10-year overall risk estimates spanned from 3.42%to 18.35%,with significant variations observed between subgroups.The proportion of high-risk individuals in the 10-year risk assessment,identified using five different tools,ranged from 7.85%to 31.94%,demonstrating moderate consistency across tools.Conclusions:The findings underscore the importance of closely monitoring and managing CVD risk in HIV-infected individuals.Given the variability in risk stratification methods,it is imperative to develop an assessment model tailored to the specific characteristics of the Chinese population.
