Elevation of serum transaminases is a frequent cause of consultation in hepatology departments.1 The most common causes of hypertransaminasemia are alcoholic and metabolic dysfunction–associated steatotic liver disea...Elevation of serum transaminases is a frequent cause of consultation in hepatology departments.1 The most common causes of hypertransaminasemia are alcoholic and metabolic dysfunction–associated steatotic liver disease,viral infections,autoimmune liver disease,celiac disease,iron overload,Wilson’s disease,and exposure to toxic compounds,including drugs.2 Although serum biochemistry,serological methods,functional approaches,imaging techniques,and liver biopsy can help to identify the etiology of liver damage,up to 15%of hypertransaminasemia cases in adults3 and 13%in children4 remain idiopathic.展开更多
基金funded by Instituto de Salud Carlos Ⅲ(PI22/00526),co-funded by the European Unionthe Ministry of Science and Innovation through the grant PID2022-140210OB-I00+2 种基金CIBERehd(EHD15PI05/2016)CIBEResp(ESP23PI08)the“Junta de Castilla y León”(SA113P23),Spain.
文摘Elevation of serum transaminases is a frequent cause of consultation in hepatology departments.1 The most common causes of hypertransaminasemia are alcoholic and metabolic dysfunction–associated steatotic liver disease,viral infections,autoimmune liver disease,celiac disease,iron overload,Wilson’s disease,and exposure to toxic compounds,including drugs.2 Although serum biochemistry,serological methods,functional approaches,imaging techniques,and liver biopsy can help to identify the etiology of liver damage,up to 15%of hypertransaminasemia cases in adults3 and 13%in children4 remain idiopathic.
