BACKGROUND Acute appendicitis(AP)is a frequently encountered surgical emergency,and appendectomy is conventionally regarded as the predominant treatment moda-lity.Nevertheless,the therapeutic efficacy of this surgical...BACKGROUND Acute appendicitis(AP)is a frequently encountered surgical emergency,and appendectomy is conventionally regarded as the predominant treatment moda-lity.Nevertheless,the therapeutic efficacy of this surgical approach remains to be improved.Thus,the exploration and implementation of surgical refinements are necessary.AIM To elucidate the therapeutic effectiveness and influencing factors of laparoscopic appendectomy(LA)with mesoappendix dissection in the treatment of AP.METHODS First,150 patients with AP who visited Shangrao Municipal Hospital between January 2022 and June 2024 were enrolled in this study.Among them,72 patients were assigned to the control group to receive conventional LA,whereas 78 cases were included in the observation group for LA with mesoappendix dissection.Subsequently,indicators such as therapeutic effectiveness,surgical indices(ope-ration time,intraoperative blood loss,and hospital stay),postoperative recovery indices(time to ambulation,gastrointestinal function recovery time,and time to food intake),incidence of adverse events(postoperative bleeding,pelvic infection,puncture site infection,and ileus),and serum inflammatory factors[tumor necro-sis factor(TNF)-α,interleukin(IL)-6,and C-reactive protein(CRP)]were collected and comparatively analyzed,and the influencing factors of therapeutic effecti-veness in patients with AP were analyzed.RESULTS Compared with the control group,the observation group had higher clinical the-rapeutic effectiveness,less operation time,intraoperative blood loss,and hospital stay;shorter time to ambulation,gastrointestinal function recovery,and food intake;and a lower total incidence of adverse events,and this difference is statistically significant.In addition,the expression levels of various serum inflammatory factors in the observation group were significantly reduced postoperatively,which were markedly lower than those in the control group.Moreover,sex,age,body mass index,time from acute onset to admission,family medical history,preoperative TNF-α,preoperative IL-6,preoperative CRP,and treatment modality were identified to be not independent factors affecting the therapeutic effectiveness of LA with mesoappendix dissection in patients with AP.CONCLUSION Overall,LA with mesoappendix dissection has a remarkable curative effect in treating patients with AP,which is worthy of clinical promotion.展开更多
目的:对比腹腔镜阑尾切除术患者中阑尾系膜电凝法与超声刀应用的效果。方法:选取我院普外科2017年3月—2018年8月收治的行腹腔镜阑尾切除术患者60例为对象,根据术中阑尾系膜的处理方法分组:对照组患者应用电凝法,观察组患者应用超声刀,...目的:对比腹腔镜阑尾切除术患者中阑尾系膜电凝法与超声刀应用的效果。方法:选取我院普外科2017年3月—2018年8月收治的行腹腔镜阑尾切除术患者60例为对象,根据术中阑尾系膜的处理方法分组:对照组患者应用电凝法,观察组患者应用超声刀,对比两组患者的围术期指标。结果:手术时间、术中出血量、术后住院时间对比,两组差异均无统计学意义, P >0.05;观察组的术后排气时间短于对照组, P <0.05。结论:腹腔镜阑尾切除术中采用超声刀和电凝法处理阑尾系膜均是可行的,均能顺利完成,但是相较于电凝法,超声刀处理系膜具有快速简便、适用范围广等优点,更有利于患者术后尽早排气,值得推广。展开更多
文摘BACKGROUND Acute appendicitis(AP)is a frequently encountered surgical emergency,and appendectomy is conventionally regarded as the predominant treatment moda-lity.Nevertheless,the therapeutic efficacy of this surgical approach remains to be improved.Thus,the exploration and implementation of surgical refinements are necessary.AIM To elucidate the therapeutic effectiveness and influencing factors of laparoscopic appendectomy(LA)with mesoappendix dissection in the treatment of AP.METHODS First,150 patients with AP who visited Shangrao Municipal Hospital between January 2022 and June 2024 were enrolled in this study.Among them,72 patients were assigned to the control group to receive conventional LA,whereas 78 cases were included in the observation group for LA with mesoappendix dissection.Subsequently,indicators such as therapeutic effectiveness,surgical indices(ope-ration time,intraoperative blood loss,and hospital stay),postoperative recovery indices(time to ambulation,gastrointestinal function recovery time,and time to food intake),incidence of adverse events(postoperative bleeding,pelvic infection,puncture site infection,and ileus),and serum inflammatory factors[tumor necro-sis factor(TNF)-α,interleukin(IL)-6,and C-reactive protein(CRP)]were collected and comparatively analyzed,and the influencing factors of therapeutic effecti-veness in patients with AP were analyzed.RESULTS Compared with the control group,the observation group had higher clinical the-rapeutic effectiveness,less operation time,intraoperative blood loss,and hospital stay;shorter time to ambulation,gastrointestinal function recovery,and food intake;and a lower total incidence of adverse events,and this difference is statistically significant.In addition,the expression levels of various serum inflammatory factors in the observation group were significantly reduced postoperatively,which were markedly lower than those in the control group.Moreover,sex,age,body mass index,time from acute onset to admission,family medical history,preoperative TNF-α,preoperative IL-6,preoperative CRP,and treatment modality were identified to be not independent factors affecting the therapeutic effectiveness of LA with mesoappendix dissection in patients with AP.CONCLUSION Overall,LA with mesoappendix dissection has a remarkable curative effect in treating patients with AP,which is worthy of clinical promotion.
文摘目的:对比腹腔镜阑尾切除术患者中阑尾系膜电凝法与超声刀应用的效果。方法:选取我院普外科2017年3月—2018年8月收治的行腹腔镜阑尾切除术患者60例为对象,根据术中阑尾系膜的处理方法分组:对照组患者应用电凝法,观察组患者应用超声刀,对比两组患者的围术期指标。结果:手术时间、术中出血量、术后住院时间对比,两组差异均无统计学意义, P >0.05;观察组的术后排气时间短于对照组, P <0.05。结论:腹腔镜阑尾切除术中采用超声刀和电凝法处理阑尾系膜均是可行的,均能顺利完成,但是相较于电凝法,超声刀处理系膜具有快速简便、适用范围广等优点,更有利于患者术后尽早排气,值得推广。