AIM:To investigate the ultrasonographic features of ciliary body mesectodermal leiomyomas(CBL).METHODS:Ultrasonographic data of 18 eyes from 18 patients with histopathologically confirmed CBL were analyzed,covering th...AIM:To investigate the ultrasonographic features of ciliary body mesectodermal leiomyomas(CBL).METHODS:Ultrasonographic data of 18 eyes from 18 patients with histopathologically confirmed CBL were analyzed,covering the period from March 2018 to February 2024.The study included 5 male and 13 female patients,aged 14-64y,with a mean age of 40.11±13.54y.The following ultrasonographic features were evaluated:tumor base diameter,thickness,maximum base diameterto-thickness ratio,shape,internal echogenicity,margin echogenicity,internal echo homogeneity,secondary changes,color Doppler flow imaging(CDFI)findings,and contrast-enhanced ultrasound(CEUS)characteristics.RESULTS:Conventional ultrasound findings of the 18 CBL cases were as follows:1)Tumor size:base diameter of(13.48±4.74)×(11.57±4.00)mm^(2),thickness of 7.70±2.60 mm,and maximum base diameter-to-thickness ratio of 1.77±0.36.2)Shape:14 cases(77.8%)were hemispherical,and 4 cases(22.2%)were irregular.3)Internal echogenicity:the solid component of the tumor was hypoechoic in 16 cases(88.9%)and low-to-medium echogenic in 2 cases(11.1%).4)Margin echogenicity:relatively hyperechoic with a“ring-shaped”margin in 15 cases(83.3%)and isoechoic in 3 cases(16.7%;compared with internal echogenicity).5)Internal echo homogeneity:homogeneous in 11 cases(61.1%)and heterogeneous in 7 cases(38.9%),with 6 cases(33.3%)among the 7 heterogeneous cases exhibiting cystic anechoic areas.6)Secondary retinal detachment was observed in 4 cases(22.2%).CDFI revealed heterogeneous vascularity within the tumors,with blood flow signals ranging from minimal to marked.CEUS was performed in 14 patients:complete contrast agent perfusion was observed in 10 cases(71.4%),and partial perfusion was noted in 4 cases(28.6%).Additionally,8 cases(57.1%)showed a rapid wash-in and slow wash-out pattern,while 6 cases(42.9%)demonstrated a rapid wash-in and rapid wash-out pattern.CONCLUSION:CBL exhibit relatively typical ultrasonographic features,which can provide valuable evidence for the clinical diagnosis and differential diagnosis of intraocular tumors.展开更多
基金Supported by National Key R&D Program of China(No.2018YFC0116000).
文摘AIM:To investigate the ultrasonographic features of ciliary body mesectodermal leiomyomas(CBL).METHODS:Ultrasonographic data of 18 eyes from 18 patients with histopathologically confirmed CBL were analyzed,covering the period from March 2018 to February 2024.The study included 5 male and 13 female patients,aged 14-64y,with a mean age of 40.11±13.54y.The following ultrasonographic features were evaluated:tumor base diameter,thickness,maximum base diameterto-thickness ratio,shape,internal echogenicity,margin echogenicity,internal echo homogeneity,secondary changes,color Doppler flow imaging(CDFI)findings,and contrast-enhanced ultrasound(CEUS)characteristics.RESULTS:Conventional ultrasound findings of the 18 CBL cases were as follows:1)Tumor size:base diameter of(13.48±4.74)×(11.57±4.00)mm^(2),thickness of 7.70±2.60 mm,and maximum base diameter-to-thickness ratio of 1.77±0.36.2)Shape:14 cases(77.8%)were hemispherical,and 4 cases(22.2%)were irregular.3)Internal echogenicity:the solid component of the tumor was hypoechoic in 16 cases(88.9%)and low-to-medium echogenic in 2 cases(11.1%).4)Margin echogenicity:relatively hyperechoic with a“ring-shaped”margin in 15 cases(83.3%)and isoechoic in 3 cases(16.7%;compared with internal echogenicity).5)Internal echo homogeneity:homogeneous in 11 cases(61.1%)and heterogeneous in 7 cases(38.9%),with 6 cases(33.3%)among the 7 heterogeneous cases exhibiting cystic anechoic areas.6)Secondary retinal detachment was observed in 4 cases(22.2%).CDFI revealed heterogeneous vascularity within the tumors,with blood flow signals ranging from minimal to marked.CEUS was performed in 14 patients:complete contrast agent perfusion was observed in 10 cases(71.4%),and partial perfusion was noted in 4 cases(28.6%).Additionally,8 cases(57.1%)showed a rapid wash-in and slow wash-out pattern,while 6 cases(42.9%)demonstrated a rapid wash-in and rapid wash-out pattern.CONCLUSION:CBL exhibit relatively typical ultrasonographic features,which can provide valuable evidence for the clinical diagnosis and differential diagnosis of intraocular tumors.
