Putin’s forceful,almost contemptuous dismissal of warnings from U. S. and European leaders about the dangerous path he was pursuing led to anxious speclation about what lay behind it. After years of pursuing a pragma...Putin’s forceful,almost contemptuous dismissal of warnings from U. S. and European leaders about the dangerous path he was pursuing led to anxious speclation about what lay behind it. After years of pursuing a pragmatic geopolitical game that was understandable,though not always appreciated by the West,Putin seemed to be operating in a different world. He had spent years courting acceptance in organizations like the G8,whose meeting he had planned on hosting in the new Sochi Winter Olympics setting,but in 2014 he seemed to be throwing everything away in pursuit of some sort of mission that few in the west understood.展开更多
This paper rethinks critically the Italian serial production of fiction, in recent years, placing it in relation to the dynamics of collective memory. The analysis starts from two Italian fiction： Raccontami, the his...This paper rethinks critically the Italian serial production of fiction, in recent years, placing it in relation to the dynamics of collective memory. The analysis starts from two Italian fiction： Raccontami, the history of a family returns the great changes of the 60s＇; I Medici dedicated to the biography of the great Florentine Renaissance banker family, exemplified by similar international productions （including the Borgia） and subject to strong promotion by Rai 1. Around these two lines of address is also the analysis of some miniseries among these biopics dedicated to figures of the national imagination such as pontiffs, doctors, partisans, entrepreneurs. If the twentieth century was defined as the ＂century of testimony＂ this is also due to the massive and pervasive presence of media that are often at the center of the processes of transformation and transition of the public and cultural life of societies. Television, in particular, confirms itself as the real, symbolic and rhetorical place in which historical events unfold, to be, on some occasions, a substitute simulacrum. Fiction, as a form of popular narrative and reworking, is an intermediary and central element in the processes of building the social imagery and collective memory, responding to the need for a typical tale of every society.展开更多
Since the 1990s,an increasing number of 1.5 generation Vietnamese-American writers who were raised and educated in America have emerged.Their writings have explored the devastating effects of the Vietnam War on immigr...Since the 1990s,an increasing number of 1.5 generation Vietnamese-American writers who were raised and educated in America have emerged.Their writings have explored the devastating effects of the Vietnam War on immigrants,offering American literature an alternative angle on the conflict.Lan Cao,a Vietnamese-American,is the author of The Lotus and the Storm which set in war-torn Vietnam.The novel’s main characters go through the excruciating anguish of losing families and displacement.Meanwhile,they suffered from everlasting trauma although they immigrated to the United States.This essay examines the novel’s ongoing war trauma and post-war memories,illustrates the post-traumatic syndrome brought on by the Vietnam War in the Vietnamese people as a whole,and investigates how practitioners heal the trauma.展开更多
This paper draws from“The Material Turn”in literary criticism to explore the multi-functions of“things”in The Book of Collateral Damage,a semi-autobiographical novel by Sinan Antoon,analyzing their roles in carryi...This paper draws from“The Material Turn”in literary criticism to explore the multi-functions of“things”in The Book of Collateral Damage,a semi-autobiographical novel by Sinan Antoon,analyzing their roles in carrying memories,constructing identities,and reconstructing history.Each object encountered in the novel holds the memories of a character,which are constructed and reconstructed as casualties of war’s collateral damage.Each object also reflects a character’s sense of social belonging,which is impacted by the collateral experiences of the war.Moreover,each object actively records and reflects the war narrative,rethinking and revising the official historical narrative.It is hoped that the present study might throw a new light on the vital role played by things in this novel,which are no longer just static backdrops,but rather dynamic narrative subjects that record and reflect individual and collective perceptions and emotions,as well as provide a more complex and multidimensional view of historical truth.展开更多
A strategic narrative is not merely a discursive account through which a state explains its behavior;it also serves as an instrument of discursive power and a key mechanism of interaction and rivalry among states.Upon...A strategic narrative is not merely a discursive account through which a state explains its behavior;it also serves as an instrument of discursive power and a key mechanism of interaction and rivalry among states.Upon his return to the White House,Donald Trump declared that“the golden age of America begins right now,”signaling a new round of adjustments to the U.S.strategic narrative.While the“golden age”narrative functions to promote the new administration’s policies externally and provide interpretive framing,it also incorporates deterrence into its broader narrative structure and employs deterrent rhetoric to project highly intense and wide-ranging aggressive discourse.展开更多
The distinctive feature of the adaptive immune system is its ability to generate immunological memory that can provide defense against subsequent infections.In the case of antibody-mediated immune responses,this memor...The distinctive feature of the adaptive immune system is its ability to generate immunological memory that can provide defense against subsequent infections.In the case of antibody-mediated immune responses,this memory comes in two cellular forms:plasma cells(PCs)and memory B cells(MBCs).PCs protect against reinfection by constitutively producing antibodies.The presence of a diverse pool of MBCs,which can expand and differentiate into PCs in secondary immune responses,is thought to be particularly important for defense against new pathogen variants.Recent studies have shown that the MBC compartment is far more heterogeneous than previously anticipated.This heterogeneity,among other factors,is shaped by their developmental pathway(germinal center(GC)vs non-GC-derived MBCs),the duration and strength of antigenic stimulation,anatomical and microanatomical localization,and the timing of generation in ontogeny.Combinations of these“layers”of MBC identities can define MBCs’properties and their fate in recall responses.Here,we review the mechanisms underlying MBC differentiation,maintenance,and reactivation and explore how the layered identity of MBCs contributes to the functions of these cells.展开更多
Aerobic exercise facilitates synaptic plasticity,thereby improving cognitive functions such as learning and memory.The 5-hydroxytryptamine system has been indicated in these processes.5-Hydroxytryptamine type 3 recept...Aerobic exercise facilitates synaptic plasticity,thereby improving cognitive functions such as learning and memory.The 5-hydroxytryptamine system has been indicated in these processes.5-Hydroxytryptamine type 3 receptors are necessary for exercise-induced hippocampal neurogenesis.Some antipsychotic drugs with 5-hydroxytryptamine type 3 receptor antagonistic properties may impede the amelioration of cognitive impairment and hippocampal plasticity induced by exercise.However,the mechanisms underlying the facilitation of synaptic plasticity by aerobic exercise have not yet been elucidated.In this study,we found that 5-hydroxytryptamine type 3 receptors played an important role in aerobic exercise-mediated improvement of hippocampal-dependent spatial and exploratory memory in mice.While 5-hydroxytryptamine type 3 receptors did not affect baseline neurogenesis in the hippocampal dentate gyrus,5-hydroxytryptamine type 3 receptors were required for aerobic exercise-induced neurogenesis and astrocyte proliferation in this region.In addition,5-hydroxytryptamine type 3 receptors were crucial for maintaining long-term potentiation in the CA1,dentate gyrus,and CA3 regions of the hippocampus.The long-term potentiation changes induced by aerobic exercise in sub-regions of the hippocampus were heterogeneous:5-hydroxytryptamine type 3 receptors were essential for aerobic exercise to enhance long-term potentiation in the CA3,but not the CA1 or dentate gyrus,regions of the hippocampus.Furthermore,aerobic exercise up-regulated 5-hydroxytryptamine type 3 receptor expression and increased brain-derived neurotrophic factor release in the hippocampus in a 5-hydroxytryptamine type 3 receptor-dependent manner.These results suggest that aerobic exercise increases hippocampal dentate gyrus neurogenesis and astrocyte proliferation via the up-regulation of 5-hydroxytryptamine type 3 receptors,leading to more brain-derived neurotrophic factor production and release from these cells,which results in long-term potentiation facilitation in the hippocampal CA3 region and help improve memory.Our findings provide insight into the mechanisms by which physical activity enhances memory and may have implications for improving memory through modulating 5-hydroxytryptamine type 3 receptor.展开更多
The main purpose of this paper is to investigate the singularities of solutions to the single Tricomi equation with derivative term and combined memory term.In addition,the blow-up of the solution to the weakly couple...The main purpose of this paper is to investigate the singularities of solutions to the single Tricomi equation with derivative term and combined memory term.In addition,the blow-up of the solution to the weakly coupled system with memory term is also considered,where one is a power nonlinear term and the other is a derivative nonlinear term.Upper bound lifespan estimates of solution are obtained in the sub-critical by utilizing the test function method and iteration technique.The innovation of this paper focuses on the lifespan estimates of the solutions,which extends the well-known Strauss and Glassey conjectures.展开更多
This article utilizes Katherine Mansfield’s short story The Garden Party as the research object to explore the narrative generation conditions of ethical experience in the text. Through a close analysis of the novel...This article utilizes Katherine Mansfield’s short story The Garden Party as the research object to explore the narrative generation conditions of ethical experience in the text. Through a close analysis of the novel’s narrative structure and key scenes, the article argues that ethical discomfort does not evolve into enduring moral judgments within the text;rather, it is continually managed and deferred through the interplay of aesthetic order, familial discourse, and the distribution of social roles. The novel eschews a linear trajectory of ethical awakening, instead crafting a narrative mechanism that keeps ethical experience palpable yet inarticulable. The female subject is given the role of sensing ethical incongruity, but lacks the narrative position from which to articulate it as judgment. Consequently, ethics remains confined to the level of personalization and unimplementability. Far from a narrative of moral growth or awakening, The Garden Party exposes why ethical judgment has become structurally unrealizable in modern narratives.展开更多
To explore effective paths for improving college students’ mental health, this study integrates narrative therapy and painting therapy to design a 7-week online group psychological counseling program. A total of 121 ...To explore effective paths for improving college students’ mental health, this study integrates narrative therapy and painting therapy to design a 7-week online group psychological counseling program. A total of 121 volunteer college students participated as subjects, and themed painting counseling was conducted via Tencent Meeting. Five scales, including the General Self-Efficacy Scale, Self-Esteem Scale, and Self-Rating Depression Scale, were used for pre-test and post-test comparisons. The results show that after the intervention, students’ self-efficacy (t = -5.528, p = 0.000) and self-esteem level (t = -2.153, p = 0.033) significantly improved statistically, and depression and anxiety showed a positive improvement trend. The research indicates that online narrative painting therapy can effectively release students’ psychological pressure, promote in-depth self-cognition and interpersonal connection construction, providing an operable innovative paradigm for college mental health education. Its interactivity and effectiveness are compatible with the psychological needs and internet usage habits of contemporary college students.展开更多
Background:In mental health,recovery is emphasized,and qualitative analyses of service users’narratives have accumulated;however,while qualitative approaches excel at capturing rich context and generating new concept...Background:In mental health,recovery is emphasized,and qualitative analyses of service users’narratives have accumulated;however,while qualitative approaches excel at capturing rich context and generating new concepts,they are limited in generalizability and feasible data volume.This study aimed to quantify the subjective life history narratives of users of psychiatric home-visit nursing using natural language processing(NLP)and to clarify the relationships between linguistic features and recovery-related indicators.Methods:We conducted audio-recorded and transcribed semi-structured interviews on daily life verbatim and collected self-report questionnaires(Recovery Assessment Scale[RAS])and clinician ratings(Global Assessment of Functioning[GAF])from Japanese users of psychiatric home-visit nursing.Using the artificial intelligence-based topic-modeling method BERTopic,we extracted topics from the interview texts and calculated each participant’s topic proportions,and then examined associations between topic proportions and recovery-related indicators using Pearson correlation analyses.Results:“School”showed a significant positive correlation with RAS(r=0.39,p=0.05),whereas“Family”showed a significant negative correlation(r=–0.46,p=0.02).GAF was positively correlated with word count(r=0.44,p=0.02)and“Hospital”(r=0.42,p=0.03),and negatively correlated with“Backchannels”(aizuchi)(r=–0.41,p=0.03).Conclusion:The present results suggest that the quantity,quality,and content of narratives can serve as useful indicators of mental health and recovery,and that objective NLP-based analysis of service users’narratives can complement traditional self-report scales and clinician ratings to inform the design of recovery-oriented care in psychiatric home-visit nursing.展开更多
Near-infrared(NIR)light-responsive shape memory polymers(SMPs)show great promise for biomedical applications,but conventional photothermal agents suffer from high cost,complex preparation,or poor biocompatibility,whil...Near-infrared(NIR)light-responsive shape memory polymers(SMPs)show great promise for biomedical applications,but conventional photothermal agents suffer from high cost,complex preparation,or poor biocompatibility,while lignin-based alternatives exhibit insufficient photothermal conversion efficiency.Herein,we developed a novel strategy to enhance photothermal performance of lignin through sequential demethylation modification and Fe^(3+)complexation for constructing NIR light responsive SMPs.Dealkaline lignin(DL)was first demethylated using iodocyclohexane to produce demethylated lignin(DDL)with increased catechol content,which was then incorporated into polycaprolactone-based polyurethane synthesis followed by Fe^(3+)complexation.Results showed that DDL-Fe^(3+)complexes have significantly enhanced photothermal conversion performance,and the resulting PU-DDL+Fe^(3+)polyurethane with 0.5 wt%DDL content demonstrated a temperature increases of 39.8℃under 0.33 W·cm-2808 nm NIR irradiation.This excellent photothermal performance enables the shape-fixed PU-DDL+Fe^(3+)polyurethane to rapidly recover to its initial shape under NIR light irradiation.Additionally,PU-DDL+Fe^(3+)polyurethane exhibits good mechanical properties and biocompatibility,demonstrating significant biomedical application potential.展开更多
This narrative review examines recent advances in salivary biomarkers for oral squamous cell carcinoma(OSCC),a major subtype of oral cancer with persistently low five-year survival rates due to delayed diagnosis.Saliv...This narrative review examines recent advances in salivary biomarkers for oral squamous cell carcinoma(OSCC),a major subtype of oral cancer with persistently low five-year survival rates due to delayed diagnosis.Saliva has emerged as a noninvasive diagnostic medium capable of reflecting both local tumor activity and systemic physiological changes.Various salivary biomarkers,including microRNAs,cytokines,proteins,metabolites,and exosomes,have been linked to oncogenic signaling pathways involved in tumor progression,immune modulation,and therapeutic resistance.Advances in quantitative polymerase chain reaction,mass spectrometry,and next-generation sequencing have enabled comprehensive biomarker profiling,while point-of-care detection systems and saliva-based omics platforms are accelerating clinical translation.Remaining challenges include variability in salivary composition,lack of standardized collection protocols,and insufficient validation across large patient cohorts.This review highlights the mechanistic relevance,diagnostic potential,and translational challenges of salivary biomarkers in OSCC.展开更多
The goal of this paper is to investigate the long-time dynamics of solutions to a Kirchhoff type suspension bridge equation with nonlinear damping and memory term.For this problem we establish the well-posedness and e...The goal of this paper is to investigate the long-time dynamics of solutions to a Kirchhoff type suspension bridge equation with nonlinear damping and memory term.For this problem we establish the well-posedness and existence of uniform attractor under some suitable assumptions on the nonlinear term g(u),the nonlinear damping f(u_(t))and the external force h(x,t).Specifically,the asymptotic compactness of the semigroup is verified by the energy reconstruction method.展开更多
GABA_(A) receptors containingα5-subunits(GABA_(A)R-α5)cluster at both extrasynaptic and synaptic locations,interacting with the scaffold proteins radixin and gephyrin,respectively,and the re-localization of GABA_(A...GABA_(A) receptors containingα5-subunits(GABA_(A)R-α5)cluster at both extrasynaptic and synaptic locations,interacting with the scaffold proteins radixin and gephyrin,respectively,and the re-localization of GABA_(A)R-α5 influences GABAergic transmission.Here,we found that when early spatial memory deficits occurred in aged mice at 24 h after sevoflurane anesthesia,there was a re-localization of GABA_(A)R-α5 that enhanced tonic inhibition and reduced the decay kinetics of miniature inhibitory postsynaptic currents in the hippocampal CA1 region.Mechanistically,increased phosphorylation of radixin at threonine 564(Thr564)mediates the re-localization of GABA_(A)R-α5.Acute treatment with the selective extrasynaptic GABA_(A)R-α5 antagonist S44819 restored the GABA_(A)R-α5-mediated inhibitory currents by reversing radixin phosphorylation-dependent GABA_(A)R-α5 re-localization,then improved the sevoflurane-induced spatial memory impairment in aged mice.Our results suggest that the localization of GABA_(A)R-α5 altered by sevoflurane is linked to unbalanced GABAergic transmission,which induces early memory impairment in aged mice.Modulating the GABA_(A)R-α5 localization might be a novel strategy to improve memory after sevoflurane exposure.展开更多
Oxide semiconductors(OSs),introduced by the Hosono group in the early 2000s,have evolved from display backplane materials to promising candidates for advanced memory and logic devices.The exceptionally low leakage cur...Oxide semiconductors(OSs),introduced by the Hosono group in the early 2000s,have evolved from display backplane materials to promising candidates for advanced memory and logic devices.The exceptionally low leakage current of OSs and compatibility with three-dimensional(3D)architectures have recently sparked renewed interest in their use in semiconductor applications.This review begins by exploring the unique material properties of OSs,which fundamentally originate from their distinct electronic band structure.Subsequently,we focus on atomic layer deposition(ALD),a core technique for growing excellent OS films,covering both basic and advanced processes compatible with 3D scaling.The basic surface reaction mechanisms—adsorption and reaction—and their roles in film growth are introduced.Furthermore,material design strategies,such as cation selection,crystallinity control,anion doping,and heterostructure engineering,are discussed.We also highlight challenges in memory applications,including contact resistance,hydrogen instability,and lack of p-type materials,and discuss the feasibility of ALD-grown OSs as potential solutions.Lastly,we provide an outlook on the role of ALD-grown OSs in memory technologies.This review bridges material fundamentals and device-level requirements,offering a comprehensive perspective on the potential of ALD-driven OSs for next-generation semiconductor memory devices.展开更多
The highly dynamic nature,strong uncertainty,and coupled multiple safety constraints inherent in carrier aircraft recovery operations pose severe challenges for real-time decision-making.Addressing bolter scenarios,th...The highly dynamic nature,strong uncertainty,and coupled multiple safety constraints inherent in carrier aircraft recovery operations pose severe challenges for real-time decision-making.Addressing bolter scenarios,this study proposes an intelligent decision-making framework based on a deep long short-term memory Q-network.This framework transforms the real-time sequencing for bolter recovery problem into a partially observable Markov decision process.It employs a stacked long shortterm memory network to accurately capture the long-range temporal dependencies of bolter event chains and fuel consumption.Furthermore,it integrates a prioritized experience replay training mechanism to construct a safe and adaptive scheduling system capable of millisecond-level real-time decision-making.Experimental demonstrates that,within large-scale mass recovery scenarios,the framework achieves zero safety violations in static environments and maintains a fuel safety violation rate below 10%in dynamic scenarios,with single-step decision times at the millisecond level.The model exhibits strong generalization capability,effectively responding to unforeseen emergent situations—such as multiple bolters and fuel emergencies—without requiring retraining.This provides robust support for efficient carrier-based aircraft recovery operations.展开更多
Shape memory polymers used in 4D printing only had one permanent shape after molding,which limited their applications in requiring multiple reconstructions and multifunctional shapes.Furthermore,the inherent stability...Shape memory polymers used in 4D printing only had one permanent shape after molding,which limited their applications in requiring multiple reconstructions and multifunctional shapes.Furthermore,the inherent stability of the triazine ring structure within cyanate ester(CE)crosslinked networks after molding posed significant challenges for both recycling,repairing,and degradation of resin.To address these obstacles,dynamic thiocyanate ester(TCE)bonds and photocurable group were incorporated into CE,obtaining the recyclable and 3D printable CE covalent adaptable networks(CANs),denoted as PTCE1.5.This material exhibits a Young's modulus of 810 MPa and a tensile strength of 50.8 MPa.Notably,damaged printed PTCE1.5 objects can be readily repaired through reprinting and interface rejoining by thermal treatment.Leveraging the solid-state plasticity,PTCE1.5 also demonstrated attractive shape memory ability and permanent shape reconfigurability,enabling its reconfigurable 4D printing.The printed PTCE1.5 hinges and a main body were assembled into a deployable and retractable satellite model,validating its potential application as a controllable component in the aerospace field.Moreover,printed PTCE1.5 can be fully degraded into thiol-modified intermediate products.Overall,this material not only enriches the application range of CE resin,but also provides a reliable approach to addressing environmental issue.展开更多
As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM c...As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM cells based on conventional silicon-based devices suffer from structural complexity and large footprintlimitations. Here, we demonstrate an ultrafast nonvolatile TCAM cell based on the MoTe2/hBN/multilayergraphene (MLG) van der Waals heterostructure using a top-gated partial floating-gate field-effect transistor(PFGFET) architecture. Based on its ambipolar transport properties, the carrier type in the source/drain andcentral channel regions of the MoTe2 channel can be efficiently tuned by the control gate and top gate, respectively,enabling the reconfigurable operation of the device in either memory or FET mode. When working inthe memory mode, it achieves an ultrafast 60 ns programming/erase speed with a current on-off ratio of ∼105,excellent retention capability, and robust endurance. When serving as a reconfigurable transistor, unipolar p-typeand n-type FETs are obtained by adopting ultrafast 60 ns control-gate voltage pulses with different polarities.The monolithic integration of memory and logic within a single device enables the content-addressable memory(CAM) functionality. Finally, by integrating two PFGFETs in parallel, a TCAM cell with a high current ratioof ∼10^(5) between the match and mismatch states is achieved without requiring additional peripheral circuitry.These results provide a promising route for the design of high-performance TCAM devices for future in-memorycomputing applications.展开更多
Programmable/reprogrammable magneto-responsive composites(MRCs)are highly desirable for applications in soft robotics,morphable actuators,and biomedical devices due to their capabilities of undergoing reversible,compl...Programmable/reprogrammable magneto-responsive composites(MRCs)are highly desirable for applications in soft robotics,morphable actuators,and biomedical devices due to their capabilities of undergoing reversible,complex,untethered,and rapid deformations.However,current MRC-based devices primarily rely on soft matrices,which revert to their original shapes and cease functioning when external magnetic fields are removed.Moreover,their magnetization programming,deformations,and functioning need to alternate between encoding and actuation platforms,limiting the adaptability and efficiency.Here,we present a reprogrammable magnetic shape-memory composite(RM-SMC)integrating a shape-memory polymer(SMP)skeleton with phase-transition magnetic microcapsules.High-intensity laser melts microcapsules for magnetic realignment under programmed fields,while low-intensity laser softens SMP for structural reconfiguration without compromising integrity.This dual-laser strategy facilitates in situ magnetization programming,shape morphing,and function execution within a single material system.Our innovative approach enables unique applications,including omnidirectional multi-degree-of-freedom actuators that can activate light switches,solar trackers that optimize energy capture,and adaptive impellers that modulate fluid pumping.By eliminating platform alternation and enabling shape/function retention post-actuation,the RM-SMC platform overcomes critical limitations in conventional MRCs,establishing a paradigm for multifunctional devices requiring persistent configuration control and field-independent operation.展开更多
文摘Putin’s forceful,almost contemptuous dismissal of warnings from U. S. and European leaders about the dangerous path he was pursuing led to anxious speclation about what lay behind it. After years of pursuing a pragmatic geopolitical game that was understandable,though not always appreciated by the West,Putin seemed to be operating in a different world. He had spent years courting acceptance in organizations like the G8,whose meeting he had planned on hosting in the new Sochi Winter Olympics setting,but in 2014 he seemed to be throwing everything away in pursuit of some sort of mission that few in the west understood.
文摘This paper rethinks critically the Italian serial production of fiction, in recent years, placing it in relation to the dynamics of collective memory. The analysis starts from two Italian fiction： Raccontami, the history of a family returns the great changes of the 60s＇; I Medici dedicated to the biography of the great Florentine Renaissance banker family, exemplified by similar international productions （including the Borgia） and subject to strong promotion by Rai 1. Around these two lines of address is also the analysis of some miniseries among these biopics dedicated to figures of the national imagination such as pontiffs, doctors, partisans, entrepreneurs. If the twentieth century was defined as the ＂century of testimony＂ this is also due to the massive and pervasive presence of media that are often at the center of the processes of transformation and transition of the public and cultural life of societies. Television, in particular, confirms itself as the real, symbolic and rhetorical place in which historical events unfold, to be, on some occasions, a substitute simulacrum. Fiction, as a form of popular narrative and reworking, is an intermediary and central element in the processes of building the social imagery and collective memory, responding to the need for a typical tale of every society.
文摘Since the 1990s,an increasing number of 1.5 generation Vietnamese-American writers who were raised and educated in America have emerged.Their writings have explored the devastating effects of the Vietnam War on immigrants,offering American literature an alternative angle on the conflict.Lan Cao,a Vietnamese-American,is the author of The Lotus and the Storm which set in war-torn Vietnam.The novel’s main characters go through the excruciating anguish of losing families and displacement.Meanwhile,they suffered from everlasting trauma although they immigrated to the United States.This essay examines the novel’s ongoing war trauma and post-war memories,illustrates the post-traumatic syndrome brought on by the Vietnam War in the Vietnamese people as a whole,and investigates how practitioners heal the trauma.
基金funded by key project of China National Social Science Fund(Project Number:19AWW007).
文摘This paper draws from“The Material Turn”in literary criticism to explore the multi-functions of“things”in The Book of Collateral Damage,a semi-autobiographical novel by Sinan Antoon,analyzing their roles in carrying memories,constructing identities,and reconstructing history.Each object encountered in the novel holds the memories of a character,which are constructed and reconstructed as casualties of war’s collateral damage.Each object also reflects a character’s sense of social belonging,which is impacted by the collateral experiences of the war.Moreover,each object actively records and reflects the war narrative,rethinking and revising the official historical narrative.It is hoped that the present study might throw a new light on the vital role played by things in this novel,which are no longer just static backdrops,but rather dynamic narrative subjects that record and reflect individual and collective perceptions and emotions,as well as provide a more complex and multidimensional view of historical truth.
文摘A strategic narrative is not merely a discursive account through which a state explains its behavior;it also serves as an instrument of discursive power and a key mechanism of interaction and rivalry among states.Upon his return to the White House,Donald Trump declared that“the golden age of America begins right now,”signaling a new round of adjustments to the U.S.strategic narrative.While the“golden age”narrative functions to promote the new administration’s policies externally and provide interpretive framing,it also incorporates deterrence into its broader narrative structure and employs deterrent rhetoric to project highly intense and wide-ranging aggressive discourse.
基金Our laboratory is supported by grants from the Swedish Research Council(2021-01468)Cancerfonden(211602 Pj and 243516 Pj)+2 种基金Barncancerfonden(PR2023-0091)Radiumhemmets Forskningsfonder(231233)the Knut and Alice Wallenberg Foundation(KAW 2024.0097).
文摘The distinctive feature of the adaptive immune system is its ability to generate immunological memory that can provide defense against subsequent infections.In the case of antibody-mediated immune responses,this memory comes in two cellular forms:plasma cells(PCs)and memory B cells(MBCs).PCs protect against reinfection by constitutively producing antibodies.The presence of a diverse pool of MBCs,which can expand and differentiate into PCs in secondary immune responses,is thought to be particularly important for defense against new pathogen variants.Recent studies have shown that the MBC compartment is far more heterogeneous than previously anticipated.This heterogeneity,among other factors,is shaped by their developmental pathway(germinal center(GC)vs non-GC-derived MBCs),the duration and strength of antigenic stimulation,anatomical and microanatomical localization,and the timing of generation in ontogeny.Combinations of these“layers”of MBC identities can define MBCs’properties and their fate in recall responses.Here,we review the mechanisms underlying MBC differentiation,maintenance,and reactivation and explore how the layered identity of MBCs contributes to the functions of these cells.
基金supported by the National Natural Science Foundation of China,Nos.31972914,31771175(both to YH).
文摘Aerobic exercise facilitates synaptic plasticity,thereby improving cognitive functions such as learning and memory.The 5-hydroxytryptamine system has been indicated in these processes.5-Hydroxytryptamine type 3 receptors are necessary for exercise-induced hippocampal neurogenesis.Some antipsychotic drugs with 5-hydroxytryptamine type 3 receptor antagonistic properties may impede the amelioration of cognitive impairment and hippocampal plasticity induced by exercise.However,the mechanisms underlying the facilitation of synaptic plasticity by aerobic exercise have not yet been elucidated.In this study,we found that 5-hydroxytryptamine type 3 receptors played an important role in aerobic exercise-mediated improvement of hippocampal-dependent spatial and exploratory memory in mice.While 5-hydroxytryptamine type 3 receptors did not affect baseline neurogenesis in the hippocampal dentate gyrus,5-hydroxytryptamine type 3 receptors were required for aerobic exercise-induced neurogenesis and astrocyte proliferation in this region.In addition,5-hydroxytryptamine type 3 receptors were crucial for maintaining long-term potentiation in the CA1,dentate gyrus,and CA3 regions of the hippocampus.The long-term potentiation changes induced by aerobic exercise in sub-regions of the hippocampus were heterogeneous:5-hydroxytryptamine type 3 receptors were essential for aerobic exercise to enhance long-term potentiation in the CA3,but not the CA1 or dentate gyrus,regions of the hippocampus.Furthermore,aerobic exercise up-regulated 5-hydroxytryptamine type 3 receptor expression and increased brain-derived neurotrophic factor release in the hippocampus in a 5-hydroxytryptamine type 3 receptor-dependent manner.These results suggest that aerobic exercise increases hippocampal dentate gyrus neurogenesis and astrocyte proliferation via the up-regulation of 5-hydroxytryptamine type 3 receptors,leading to more brain-derived neurotrophic factor production and release from these cells,which results in long-term potentiation facilitation in the hippocampal CA3 region and help improve memory.Our findings provide insight into the mechanisms by which physical activity enhances memory and may have implications for improving memory through modulating 5-hydroxytryptamine type 3 receptor.
基金Supported by National Natural Science Foundation of China Under Grant(12401647)Supported by Fundamental Research Program of Shanxi Province(202203021212336)+2 种基金Taiyuan Institute of Technology Scientific Research Initial Funding(2023KJ057,2024KJ007,2024LJ005)Supported by Scientific and Technologial Innovation Programs of Higher Education Institutions in Shanxi(2024L358)Youth Program of Taiyuan University(24TYQN10)。
文摘The main purpose of this paper is to investigate the singularities of solutions to the single Tricomi equation with derivative term and combined memory term.In addition,the blow-up of the solution to the weakly coupled system with memory term is also considered,where one is a power nonlinear term and the other is a derivative nonlinear term.Upper bound lifespan estimates of solution are obtained in the sub-critical by utilizing the test function method and iteration technique.The innovation of this paper focuses on the lifespan estimates of the solutions,which extends the well-known Strauss and Glassey conjectures.
文摘This article utilizes Katherine Mansfield’s short story The Garden Party as the research object to explore the narrative generation conditions of ethical experience in the text. Through a close analysis of the novel’s narrative structure and key scenes, the article argues that ethical discomfort does not evolve into enduring moral judgments within the text;rather, it is continually managed and deferred through the interplay of aesthetic order, familial discourse, and the distribution of social roles. The novel eschews a linear trajectory of ethical awakening, instead crafting a narrative mechanism that keeps ethical experience palpable yet inarticulable. The female subject is given the role of sensing ethical incongruity, but lacks the narrative position from which to articulate it as judgment. Consequently, ethics remains confined to the level of personalization and unimplementability. Far from a narrative of moral growth or awakening, The Garden Party exposes why ethical judgment has become structurally unrealizable in modern narratives.
基金General Project of the 14th Five-Year Plan for Educational Science in Liaoning Province(2025):“Teaching Research on Group Narrative Painting Training to Improve College Students’Self-Efficacy and Psychological Resilience”(Project No.:JG25DB118)。
文摘To explore effective paths for improving college students’ mental health, this study integrates narrative therapy and painting therapy to design a 7-week online group psychological counseling program. A total of 121 volunteer college students participated as subjects, and themed painting counseling was conducted via Tencent Meeting. Five scales, including the General Self-Efficacy Scale, Self-Esteem Scale, and Self-Rating Depression Scale, were used for pre-test and post-test comparisons. The results show that after the intervention, students’ self-efficacy (t = -5.528, p = 0.000) and self-esteem level (t = -2.153, p = 0.033) significantly improved statistically, and depression and anxiety showed a positive improvement trend. The research indicates that online narrative painting therapy can effectively release students’ psychological pressure, promote in-depth self-cognition and interpersonal connection construction, providing an operable innovative paradigm for college mental health education. Its interactivity and effectiveness are compatible with the psychological needs and internet usage habits of contemporary college students.
文摘Background:In mental health,recovery is emphasized,and qualitative analyses of service users’narratives have accumulated;however,while qualitative approaches excel at capturing rich context and generating new concepts,they are limited in generalizability and feasible data volume.This study aimed to quantify the subjective life history narratives of users of psychiatric home-visit nursing using natural language processing(NLP)and to clarify the relationships between linguistic features and recovery-related indicators.Methods:We conducted audio-recorded and transcribed semi-structured interviews on daily life verbatim and collected self-report questionnaires(Recovery Assessment Scale[RAS])and clinician ratings(Global Assessment of Functioning[GAF])from Japanese users of psychiatric home-visit nursing.Using the artificial intelligence-based topic-modeling method BERTopic,we extracted topics from the interview texts and calculated each participant’s topic proportions,and then examined associations between topic proportions and recovery-related indicators using Pearson correlation analyses.Results:“School”showed a significant positive correlation with RAS(r=0.39,p=0.05),whereas“Family”showed a significant negative correlation(r=–0.46,p=0.02).GAF was positively correlated with word count(r=0.44,p=0.02)and“Hospital”(r=0.42,p=0.03),and negatively correlated with“Backchannels”(aizuchi)(r=–0.41,p=0.03).Conclusion:The present results suggest that the quantity,quality,and content of narratives can serve as useful indicators of mental health and recovery,and that objective NLP-based analysis of service users’narratives can complement traditional self-report scales and clinician ratings to inform the design of recovery-oriented care in psychiatric home-visit nursing.
基金supported by the National Natural Science Foundation of China(Nos.51603005,52403186 and 52573150)Fujian Provincial Natural Science Foundation of China(No.2024J011447)+1 种基金Natural Science Foundation of Xiamen,China(No.3502Z20227305)the Postdoctoral Fellowship Program of CPSF(No.GZC20240095)。
文摘Near-infrared(NIR)light-responsive shape memory polymers(SMPs)show great promise for biomedical applications,but conventional photothermal agents suffer from high cost,complex preparation,or poor biocompatibility,while lignin-based alternatives exhibit insufficient photothermal conversion efficiency.Herein,we developed a novel strategy to enhance photothermal performance of lignin through sequential demethylation modification and Fe^(3+)complexation for constructing NIR light responsive SMPs.Dealkaline lignin(DL)was first demethylated using iodocyclohexane to produce demethylated lignin(DDL)with increased catechol content,which was then incorporated into polycaprolactone-based polyurethane synthesis followed by Fe^(3+)complexation.Results showed that DDL-Fe^(3+)complexes have significantly enhanced photothermal conversion performance,and the resulting PU-DDL+Fe^(3+)polyurethane with 0.5 wt%DDL content demonstrated a temperature increases of 39.8℃under 0.33 W·cm-2808 nm NIR irradiation.This excellent photothermal performance enables the shape-fixed PU-DDL+Fe^(3+)polyurethane to rapidly recover to its initial shape under NIR light irradiation.Additionally,PU-DDL+Fe^(3+)polyurethane exhibits good mechanical properties and biocompatibility,demonstrating significant biomedical application potential.
基金supported by the College of Oral Medicine,Taipei Medical University,Taipei,Taiwan(Grant No.TMUCOM202502)supported by Taipei Medical University Hospital,Taipei,Taiwan(Grant No.114TMUH-NE-05).
文摘This narrative review examines recent advances in salivary biomarkers for oral squamous cell carcinoma(OSCC),a major subtype of oral cancer with persistently low five-year survival rates due to delayed diagnosis.Saliva has emerged as a noninvasive diagnostic medium capable of reflecting both local tumor activity and systemic physiological changes.Various salivary biomarkers,including microRNAs,cytokines,proteins,metabolites,and exosomes,have been linked to oncogenic signaling pathways involved in tumor progression,immune modulation,and therapeutic resistance.Advances in quantitative polymerase chain reaction,mass spectrometry,and next-generation sequencing have enabled comprehensive biomarker profiling,while point-of-care detection systems and saliva-based omics platforms are accelerating clinical translation.Remaining challenges include variability in salivary composition,lack of standardized collection protocols,and insufficient validation across large patient cohorts.This review highlights the mechanistic relevance,diagnostic potential,and translational challenges of salivary biomarkers in OSCC.
基金Supported by the National Natural Science Foundation of China(Grant Nos.11961059,1210502)the University Innovation Project of Gansu Province(Grant No.2023B-062)the Gansu Province Basic Research Innovation Group Project(Grant No.23JRRA684).
文摘The goal of this paper is to investigate the long-time dynamics of solutions to a Kirchhoff type suspension bridge equation with nonlinear damping and memory term.For this problem we establish the well-posedness and existence of uniform attractor under some suitable assumptions on the nonlinear term g(u),the nonlinear damping f(u_(t))and the external force h(x,t).Specifically,the asymptotic compactness of the semigroup is verified by the energy reconstruction method.
基金supported by the Tianjin Scientific Research Start-up Foundation for Talent Introduction(2021-1-10)the 14th Five-Year Plan Peak Discipline Support Plan of Tianjin Medical University Cancer Institute and Hospital(7-2-13)+3 种基金National Natural Science Foundation of China(82171221),Beijing Bethune Charitable Foundation(YXJL-2024-0778-0030)Beijing Science and Technology Innovation Medical Development Foundation(KC2024-JF-0069)Tianjin Medical University Postgraduate Education Reform Research Program(TMUYY02)Tianjin Key Medical Discipline(Specialty)Construction(TJYXZDXK-009A).
文摘GABA_(A) receptors containingα5-subunits(GABA_(A)R-α5)cluster at both extrasynaptic and synaptic locations,interacting with the scaffold proteins radixin and gephyrin,respectively,and the re-localization of GABA_(A)R-α5 influences GABAergic transmission.Here,we found that when early spatial memory deficits occurred in aged mice at 24 h after sevoflurane anesthesia,there was a re-localization of GABA_(A)R-α5 that enhanced tonic inhibition and reduced the decay kinetics of miniature inhibitory postsynaptic currents in the hippocampal CA1 region.Mechanistically,increased phosphorylation of radixin at threonine 564(Thr564)mediates the re-localization of GABA_(A)R-α5.Acute treatment with the selective extrasynaptic GABA_(A)R-α5 antagonist S44819 restored the GABA_(A)R-α5-mediated inhibitory currents by reversing radixin phosphorylation-dependent GABA_(A)R-α5 re-localization,then improved the sevoflurane-induced spatial memory impairment in aged mice.Our results suggest that the localization of GABA_(A)R-α5 altered by sevoflurane is linked to unbalanced GABAergic transmission,which induces early memory impairment in aged mice.Modulating the GABA_(A)R-α5 localization might be a novel strategy to improve memory after sevoflurane exposure.
基金supported by National Research Foundation of Korea(NRF)funded by Ministry of Science and ICT(MSIT)(No.RS-2023-00260527,RS-2024-00407282,RS-2025-00557667)supported by Hanyang University Industry-University Cooperation Foundation(No.202400000003943)supported by Korea Planning&Evaluation Institute of Industrial Technology(KEIT)funded by South Korean Ministry of Trade,Industry and Energy(MOTIE)(No.RS-2025-25454815,RS-2025-02308064,20017382)。
文摘Oxide semiconductors(OSs),introduced by the Hosono group in the early 2000s,have evolved from display backplane materials to promising candidates for advanced memory and logic devices.The exceptionally low leakage current of OSs and compatibility with three-dimensional(3D)architectures have recently sparked renewed interest in their use in semiconductor applications.This review begins by exploring the unique material properties of OSs,which fundamentally originate from their distinct electronic band structure.Subsequently,we focus on atomic layer deposition(ALD),a core technique for growing excellent OS films,covering both basic and advanced processes compatible with 3D scaling.The basic surface reaction mechanisms—adsorption and reaction—and their roles in film growth are introduced.Furthermore,material design strategies,such as cation selection,crystallinity control,anion doping,and heterostructure engineering,are discussed.We also highlight challenges in memory applications,including contact resistance,hydrogen instability,and lack of p-type materials,and discuss the feasibility of ALD-grown OSs as potential solutions.Lastly,we provide an outlook on the role of ALD-grown OSs in memory technologies.This review bridges material fundamentals and device-level requirements,offering a comprehensive perspective on the potential of ALD-driven OSs for next-generation semiconductor memory devices.
基金supported by the National Natural Science Foundation of China(Grant No.62403486)。
文摘The highly dynamic nature,strong uncertainty,and coupled multiple safety constraints inherent in carrier aircraft recovery operations pose severe challenges for real-time decision-making.Addressing bolter scenarios,this study proposes an intelligent decision-making framework based on a deep long short-term memory Q-network.This framework transforms the real-time sequencing for bolter recovery problem into a partially observable Markov decision process.It employs a stacked long shortterm memory network to accurately capture the long-range temporal dependencies of bolter event chains and fuel consumption.Furthermore,it integrates a prioritized experience replay training mechanism to construct a safe and adaptive scheduling system capable of millisecond-level real-time decision-making.Experimental demonstrates that,within large-scale mass recovery scenarios,the framework achieves zero safety violations in static environments and maintains a fuel safety violation rate below 10%in dynamic scenarios,with single-step decision times at the millisecond level.The model exhibits strong generalization capability,effectively responding to unforeseen emergent situations—such as multiple bolters and fuel emergencies—without requiring retraining.This provides robust support for efficient carrier-based aircraft recovery operations.
基金supported by the National Natural Science Foundation of China(Nos.52473080,52403167 and 52173079)the Fundamental Research Funds for the Central Universities(Nos.xtr052023001 and xzy012023037)+1 种基金the Postdoctoral Research Project of Shaanxi Province(No.2024BSHSDZZ054)the Shaanxi Laboratory of Advanced Materials(No.2024ZY-JCYJ-04-12).
文摘Shape memory polymers used in 4D printing only had one permanent shape after molding,which limited their applications in requiring multiple reconstructions and multifunctional shapes.Furthermore,the inherent stability of the triazine ring structure within cyanate ester(CE)crosslinked networks after molding posed significant challenges for both recycling,repairing,and degradation of resin.To address these obstacles,dynamic thiocyanate ester(TCE)bonds and photocurable group were incorporated into CE,obtaining the recyclable and 3D printable CE covalent adaptable networks(CANs),denoted as PTCE1.5.This material exhibits a Young's modulus of 810 MPa and a tensile strength of 50.8 MPa.Notably,damaged printed PTCE1.5 objects can be readily repaired through reprinting and interface rejoining by thermal treatment.Leveraging the solid-state plasticity,PTCE1.5 also demonstrated attractive shape memory ability and permanent shape reconfigurability,enabling its reconfigurable 4D printing.The printed PTCE1.5 hinges and a main body were assembled into a deployable and retractable satellite model,validating its potential application as a controllable component in the aerospace field.Moreover,printed PTCE1.5 can be fully degraded into thiol-modified intermediate products.Overall,this material not only enriches the application range of CE resin,but also provides a reliable approach to addressing environmental issue.
基金supported by the National Key Research&Development Projects of China(Grant No.2022YFA1204100)National Natural Science Foundation of China(Grant No.62488201)+1 种基金CAS Project for Young Scientists in Basic Research(YSBR-003)the Innovation Program of Quantum Science and Technology(2021ZD0302700)。
文摘As a typical in-memory computing hardware design, nonvolatile ternary content-addressable memories(TCAMs) enable the logic operation and data storage for high throughout in parallel big data processing. However,TCAM cells based on conventional silicon-based devices suffer from structural complexity and large footprintlimitations. Here, we demonstrate an ultrafast nonvolatile TCAM cell based on the MoTe2/hBN/multilayergraphene (MLG) van der Waals heterostructure using a top-gated partial floating-gate field-effect transistor(PFGFET) architecture. Based on its ambipolar transport properties, the carrier type in the source/drain andcentral channel regions of the MoTe2 channel can be efficiently tuned by the control gate and top gate, respectively,enabling the reconfigurable operation of the device in either memory or FET mode. When working inthe memory mode, it achieves an ultrafast 60 ns programming/erase speed with a current on-off ratio of ∼105,excellent retention capability, and robust endurance. When serving as a reconfigurable transistor, unipolar p-typeand n-type FETs are obtained by adopting ultrafast 60 ns control-gate voltage pulses with different polarities.The monolithic integration of memory and logic within a single device enables the content-addressable memory(CAM) functionality. Finally, by integrating two PFGFETs in parallel, a TCAM cell with a high current ratioof ∼10^(5) between the match and mismatch states is achieved without requiring additional peripheral circuitry.These results provide a promising route for the design of high-performance TCAM devices for future in-memorycomputing applications.
基金supported by the National Natural Science Foundation of China(Nos.52075516,61927814,62325507,and 52122511)the National Key Research and Development Program of China(No.2021YFF0502700)+2 种基金the Major Scientific and Technological Projects in Anhui Province(202103a05020005,202203a05020014)the Students’Innovation and Entrepreneurship Foundation of USTC(CY2022G09)the Hefei Municipal Natural Science Foundation(No.HZR2450)。
文摘Programmable/reprogrammable magneto-responsive composites(MRCs)are highly desirable for applications in soft robotics,morphable actuators,and biomedical devices due to their capabilities of undergoing reversible,complex,untethered,and rapid deformations.However,current MRC-based devices primarily rely on soft matrices,which revert to their original shapes and cease functioning when external magnetic fields are removed.Moreover,their magnetization programming,deformations,and functioning need to alternate between encoding and actuation platforms,limiting the adaptability and efficiency.Here,we present a reprogrammable magnetic shape-memory composite(RM-SMC)integrating a shape-memory polymer(SMP)skeleton with phase-transition magnetic microcapsules.High-intensity laser melts microcapsules for magnetic realignment under programmed fields,while low-intensity laser softens SMP for structural reconfiguration without compromising integrity.This dual-laser strategy facilitates in situ magnetization programming,shape morphing,and function execution within a single material system.Our innovative approach enables unique applications,including omnidirectional multi-degree-of-freedom actuators that can activate light switches,solar trackers that optimize energy capture,and adaptive impellers that modulate fluid pumping.By eliminating platform alternation and enabling shape/function retention post-actuation,the RM-SMC platform overcomes critical limitations in conventional MRCs,establishing a paradigm for multifunctional devices requiring persistent configuration control and field-independent operation.
