In China, CM has been applied to treat almost every cancer patient, especially during the observation period after surgery, routine radiotherapy and chemotherapy. Several decades of CM treatment results have shown tha...In China, CM has been applied to treat almost every cancer patient, especially during the observation period after surgery, routine radiotherapy and chemotherapy. Several decades of CM treatment results have shown that CM treatment could be helpful in improving patients＇ physical rehabilitation, relieving symptoms and strengthening immunity. CM also could aid in the decline of rates of recurrence and metastasis, prolong the survival time, and especially, have significant effects on relieving symptoms such as relieving fatigue, improving syndromes caused by conventional therapies （surgery, radiotherapy, chemotherapy and biological treatment）, and indescribable discomforts caused by the unknown reason. It has been found in several studies that conventional medical treatment combined with CM could significantly improve QOL, and reduce treatment-related and disease-related symptoms. Patients treated with CM and Western medicine have higher scores in the fields of psychology, society,展开更多
Objective：To assess the efficacy of Chinese medicine（CM） on patients with pancreatic cancer（PC） in a retrospective population-based study.Methods：Between January 1,2013,and August 30,2016,according to whether re...Objective：To assess the efficacy of Chinese medicine（CM） on patients with pancreatic cancer（PC） in a retrospective population-based study.Methods：Between January 1,2013,and August 30,2016,according to whether received Western medicine treatment,the patients were included into either integrative medicine（IM） group or CM group.All enrolled patients were orally administrated with Gexia Zhuyu Decoction（膈下逐瘀汤） or Liujun Ermu Decoction（六君二母汤） by syndrome differentiation,twice a day,last for at least 2 months.The primary end point was overall survival（OS）.Results：A total of 174 patients with PC were enrolled in this study.In stage Ⅰ/Ⅱ,the median OS was 20.5 months in the IM group [95% confidence interval（CI）,12.499 to 28.501] and 11.17 months in the CM group（95% CI,5.160 to 17.180,P=0.015）.The 1-and 2-year survival rates for the two groups were 47.0%,40.0% and 21.0%,21.0%,respectively.In stage Ⅲ/Ⅳ,median OS was 13.53 months（95% CI,8.665 to 18.395） in the IM group versus 6.4 months（95% CI,0.00 to 15.682） in the CM group,respectively（P=0.32）.The 1-and 2-year survival rate for the IM and CM groups were 27.0%,7.0% and 20.0%,2.0%,respectively.Conclusions：Intervention of CM contributes to the different survival benefits for PC in different stages.Multimodality treatment might be a promising strategy for PC patients in early stage.While,in advanced stage,CM might be an alternative candidate for PC patients.展开更多
文摘In China, CM has been applied to treat almost every cancer patient, especially during the observation period after surgery, routine radiotherapy and chemotherapy. Several decades of CM treatment results have shown that CM treatment could be helpful in improving patients＇ physical rehabilitation, relieving symptoms and strengthening immunity. CM also could aid in the decline of rates of recurrence and metastasis, prolong the survival time, and especially, have significant effects on relieving symptoms such as relieving fatigue, improving syndromes caused by conventional therapies （surgery, radiotherapy, chemotherapy and biological treatment）, and indescribable discomforts caused by the unknown reason. It has been found in several studies that conventional medical treatment combined with CM could significantly improve QOL, and reduce treatment-related and disease-related symptoms. Patients treated with CM and Western medicine have higher scores in the fields of psychology, society,
基金Supported by the National Natural Science Foundation of China(No.81673797)
文摘Objective：To assess the efficacy of Chinese medicine（CM） on patients with pancreatic cancer（PC） in a retrospective population-based study.Methods：Between January 1,2013,and August 30,2016,according to whether received Western medicine treatment,the patients were included into either integrative medicine（IM） group or CM group.All enrolled patients were orally administrated with Gexia Zhuyu Decoction（膈下逐瘀汤） or Liujun Ermu Decoction（六君二母汤） by syndrome differentiation,twice a day,last for at least 2 months.The primary end point was overall survival（OS）.Results：A total of 174 patients with PC were enrolled in this study.In stage Ⅰ/Ⅱ,the median OS was 20.5 months in the IM group [95% confidence interval（CI）,12.499 to 28.501] and 11.17 months in the CM group（95% CI,5.160 to 17.180,P=0.015）.The 1-and 2-year survival rates for the two groups were 47.0%,40.0% and 21.0%,21.0%,respectively.In stage Ⅲ/Ⅳ,median OS was 13.53 months（95% CI,8.665 to 18.395） in the IM group versus 6.4 months（95% CI,0.00 to 15.682） in the CM group,respectively（P=0.32）.The 1-and 2-year survival rate for the IM and CM groups were 27.0%,7.0% and 20.0%,2.0%,respectively.Conclusions：Intervention of CM contributes to the different survival benefits for PC in different stages.Multimodality treatment might be a promising strategy for PC patients in early stage.While,in advanced stage,CM might be an alternative candidate for PC patients.
