This study examines how organizational support influences the career adaptability of novice university teachers in Guangdong,China,and the mediating role of teacher self-efficacy.Drawing on social cognitive theory and...This study examines how organizational support influences the career adaptability of novice university teachers in Guangdong,China,and the mediating role of teacher self-efficacy.Drawing on social cognitive theory and organizational support theory,we hypothesized that organizational support would positively predict career adaptability through self-efficacy.A cross-sectional survey was conducted with 326 novice teachers(with 1–3 years of teaching experience)from 12 universities in Guangdong.Data were analyzed using correlation analysis,hierarchical regression,and bootstrap.Results showed that:(1)organizational support was positively associated with both self-efficacy(r=0.62,P<0.001)and career adaptability(r=0.58,P<0.001);(2)self-efficacy fully mediated the relationship between organizational support and career adaptability(indirect effect=0.24,95%CI[0.18,0.31]),with a partial reduction in the direct effect fromβ=0.35 toβ=0.17(P<0.05);(3)female teachers reported higher self-efficacy than males(P<0.05),and teachers with 2 years of experience showed significantly higher adaptability than those with 1 year(P<0.05).The findings highlight the critical role of self-efficacy in translating organizational support into adaptability,providing empirical evidence for universities to design targeted support strategies.展开更多
Background:Childhood environmental unpredictability(CEU)is crucial to personal development,profoundly influence physical and psychological growth particularly,and psychopathy is recognized as a dark personality trait....Background:Childhood environmental unpredictability(CEU)is crucial to personal development,profoundly influence physical and psychological growth particularly,and psychopathy is recognized as a dark personality trait.The aim of this study is to investigate the effects of insecure attachment and life history strategy(LHS)on the relationship between CEU and psychopathy by establishing a sequential mediation model based on evolutionary life history theory and cognitive-affective personality system.Methods:A group of 532 undergraduates completed the measurements for CEU,insecure attachment,LHS,and psychopathy,and Bootstrap mediation test through SPSS 25.0 and PROCESS macro tool was used to examine the relationship among these variables.Results:The results revealed positive relations between CEU and insecure attachment(β=0.87,p<0.001),CEU and LHS(β=0.11,p<0.001),and CEU and psychopathy(β=0.14,p<0.001).Insecure attachment was also positively associated with LHS(β=0.62,p<0.001)and psychopathy(β=0.04,p<0.001).In addition,LHS was significantly associated with psychopathy(β=0.08,p<0.001).The relationship between CEU and psychopathy is mediated independently and sequentially by insecure attachment and LHS.Conclusion:The current research shows the relationship between CEU and psychopathy,as well as the mechanism of insecure attachment and life history strategy as mediators.展开更多
Objective:To analyze the mediating effect of psychological flexibility between death anxiety and quality of life in cancer patients.Methods:A convenience sampling method was used to select cancer patients who received...Objective:To analyze the mediating effect of psychological flexibility between death anxiety and quality of life in cancer patients.Methods:A convenience sampling method was used to select cancer patients who received treatment at our hospital from January 2022 to January 2024,by the inclusion and exclusion criteria.General information,psychological flexibility,death anxiety,and quality of life scores were collected for analysis.Result:The psychological flexibility and quality of life scores of cancer patients with an annual family income≤100,000 RMB were significantly lower than those of cancer patients with an annual family income>100,000 RMB(P<0.05),while the death anxiety scores were significantly lower for the former group as well(P<0.05).Cancer patients staged as Ⅰ-Ⅱ had significantly higher psychological flexibility and quality of life scores than those staged as Ⅲ-Ⅳ(P<0.05),while their death anxiety scores were significantly lower(P<0.05).Psychological flexibility in cancer patients was negatively correlated with death anxiety(r=-0.614,P<0.05)and positively correlated with quality of life(r=0.628,P<0.05),while death anxiety was negatively correlated with quality of life(r=-0.112,P<0.05).The direct effect of death anxiety on quality of life was-0.232,accounting for 58.32%of the total effect.The mediating effect of psychological flexibility between death anxiety and quality of life was-0.218,accounting for 41.83%of the total effect.Conclusion:Death anxiety can directly affect the quality of life of cancer patients,and it can also indirectly affect the quality of life through psychological flexibility.Clinicians should promptly address patients’death anxiety and provide interventions to enhance psychological flexibility,thereby improving the quality of life.展开更多
Objective:Investigating the Mediating Role of Pain in the Relationship Between Sleep Quality and Health-Related Quality of Life Among Elderly Patients with Chronic Diseases.Methods:Using data from the 2018 China Healt...Objective:Investigating the Mediating Role of Pain in the Relationship Between Sleep Quality and Health-Related Quality of Life Among Elderly Patients with Chronic Diseases.Methods:Using data from the 2018 China Health and Retirement Longitudinal Study(CHARLS),this study included 3,284 participants aged 60 years or older with chronic diseases.The sleep quality,pain status,health-related quality of life,and demographic-related data of these elderly patients were obtained.Pearson correlation analysis was conducted to assess the bivariate relationships among the variables.The mediating role of pain in the sleep quality-HRQoL relationship was tested using linear regression models,complemented by bootstrap sampling to verify the indirect effect.Results:Sleep quality was positively associated with health-related quality of life(r=0.218,p<0.001).Conversely,pain demonstrated significant negative correlations with both sleep quality(r=-0.496,p<0.001)and health-related quality of life(r=-0.067,p<0.001).The mediating effect results showed that pain played a partial mediating role between sleep quality and health-related quality of life in elderly patients with chronic diseases(effect value=0.049),and the mediating effect accounted for 23.33%.Conclusion:Pain is a mediating variable between sleep quality and health-related quality of life in elderly patients with chronic diseases.This suggests that clinical practice should incorporate pain assessment into standard clinical care of elderly patients with sleep disorders and chronic diseases.By alleviating pain,sleep quality can be improved,and subsequently,their health-related quality of life can be enhanced.展开更多
BACKGROUND Several studies have suggested a close link between depression,overweight,and new-onset diabetes,particularly among middle-aged and older populations;however,the causal associations remain poorly understood...BACKGROUND Several studies have suggested a close link between depression,overweight,and new-onset diabetes,particularly among middle-aged and older populations;however,the causal associations remain poorly understood.AIM To investigate the role of overweight in mediating the association between depression and new-onset diabetes in middle-aged and older populations.METHODS Data of 9426 individuals aged≥50 years from the 1998-2016 Health and Retirement Study database were analyzed.Weighted logistic regression was employed to obtain odds ratios(ORs)and 95%confidence intervals(95%CIs)for depression and new-onset diabetes in the middle-aged and older populations.Mediation analysis and the Sobel test were used to test the mediating effects of overweight between depression and the risk of new-onset diabetes.RESULTS New-onset diabetes was identified in 23.6%of the study population.Depression was significantly associated with new-onset diabetes(OR:1.18,95%CI:1.03-1.35,P value:0.014).Further adjustment for overweight attenuated the effect of depression on new-onset diabetes to 1.14(95%CI:1.00-1.30,P=0.053),with a significant mediating effect(P of Sobel test=0.003).The mediation analysis demonstrated that overweight accounted for 61%in depression for the risk of new-onset diabetes,with overweight having a partially mediating role in the depression-to-diabetes pathway.CONCLUSION New-onset diabetes was not necessarily a direct complication of depression;rather,depression led to behaviors that increase the risk of overweight and,consequently,new-onset diabetes.展开更多
New-type urbanization(NTU)is proposed by China to solve unsustainable issues and improve green development efficiency(GDE)during the process of rapid urbanization.However,the impact mechanism of NTU on GDE is unclear....New-type urbanization(NTU)is proposed by China to solve unsustainable issues and improve green development efficiency(GDE)during the process of rapid urbanization.However,the impact mechanism of NTU on GDE is unclear.Using panel data of 282 prefecture-level cities in China from 2010 to 2019,we measured NTU and GDE to describe their spatiotemporal pattern and relationship evolution.The fixed effects panel model and mediating effect panel model were further utilized to analyze the benchmark impact,mediating mechanism and spatiotem-poral heterogeneity of NTU on GDE.The results showed that NTU improved,with the highest levels observed in the eastern region,while GDE increased with fluctuations,performing better in both the eastern and western regions.With the proportion of double-high cities increasing from 13.83%to 43.62%,the NTU-GDE relationship was upgraded.Overall,every 1%improvement in NTU increased GDE by 0.3111%,and the enterprise effect,resident effect and government effect played a positive mediating role from high to low.During the later stage of NTU,its impact on GDE strengthened significantly,and the mediating role of governments was optimized.The eastern region was the only region with three positive mediating roles of governments,enterprises and residents.These findings will promote GDE through NTU in China and serve as a valuable reference for sustainable global urbanization.展开更多
With the development of minimally invasive gynecological technology,hysteroscopic surgery has been widely used in the treatment of gynecological diseases due to its advantages of rapid recovery and minimal trauma.From...With the development of minimally invasive gynecological technology,hysteroscopic surgery has been widely used in the treatment of gynecological diseases due to its advantages of rapid recovery and minimal trauma.From the perspective of patients undergoing hysteroscopic surgery,this paper explores the influence of their psychological security on quality of life,analyzes the mediating effect of social support,and puts forward specific countermeasures and suggestions.The purpose is to improve the psychological security and quality of life of patients undergoing hysteroscopic surgery,and provide reference for the subsequent development of hysteroscopic surgery.展开更多
BACKGROUND Depression is a leading global health concern with high suicide rates and recurrence.Cognitive models suggest that mental pain and automatic thoughts are central to depression's impact.The hypothesis is...BACKGROUND Depression is a leading global health concern with high suicide rates and recurrence.Cognitive models suggest that mental pain and automatic thoughts are central to depression's impact.The hypothesis is that self-compassion will be negatively associated with mental pain,mediated by automatic thoughts.AIM To determine the mediating role of automatic thoughts in the relationship between self-compassion and mental pain in individuals with depression.METHODS This cross-sectional study included 389 inpatients with depression from Tianjin Anding Hospital.Participants completed the Self-Compassion Scale-Chinese Version(SCS-C),Automatic Thought Questionnaire(ATQ),and Orbach&Mikulincer Mental Pain Scale-Chinese Version(OMMP).Data were analyzed using Pearson correlations,multiple linear regressions,and mediation analysis.RESULTS The SCS-C total score was 68.95±14.89,ATQ was 87.02±28.91,and OMMP was 129.01±36.74.Correlation analysis showed mental pain was positively associated with automatic thoughts(r=0.802,P<0.001)and negatively with selfcompassion(r=-0.636,P<0.001).Regression analysis indicated automatic thoughts(β=0.623,P<0.001)and self-compassion(β=-0.301,P<0.001)significantly predicted mental pain.Mediation analysis confirmed automatic thoughts partially mediated the relationship between self-compassion and mental pain(ab=-0.269,95%CI:-0.363 to-0.212).CONCLUSION Self-compassion is inversely related to mental pain in depression,with automatic thoughts playing a mediating role.These findings suggest potential therapeutic targets for alleviating mental pain in depressed patients.展开更多
Background:Recent scholarly attention has increasingly focused on filial piety beliefs'impact on youth's psychological development.However,the mechanisms by which filial piety indirectly influences adolescent ...Background:Recent scholarly attention has increasingly focused on filial piety beliefs'impact on youth's psychological development.However,the mechanisms by which filial piety indirectly influences adolescent autonomy through depression and well-being remain underexplored.This study aimed to test a sequential mediation model among filial piety beliefs,depression,well-being,and autonomy in Taiwan region of China university students.Methods:A total of 566 Taiwan region of China undergraduate and graduate students,comprising 390 females and 176 males,and including 399 undergraduates and 167 graduate students,were recruited through convenience sampling.Data were collected via an online questionnaire.Validated instruments were employed,including the Filial Piety Scale(FPS),the Center for Epidemiological Studies Depression Scale(CES-D),the Chinese Well-being Inventory(CHI),and the Adolescent Autonomy Scale-Short Form(AAS-SF).Statistical analyses included group comparisons,correlation analyses,and structural equation modeling to examine the hypothesized relationships and mediation effects.Results:The results revealed that filial piety beliefs exerted a significant positive impact on adolescent autonomy,with depression and well-being serving as key mediators in this relationship.A sequential mediation effect was confirmed through structural equation modeling(β=0.052,95%CI[0.028,0.091]),with good model fit indices(x^(2)/df=4.25,RMSEA=0.076,CFI=0.968),supporting the hypothesized pathway from filial piety to autonomy via depression and well-being.In terms of demographic differences,male students showed significantly higher autonomy than females(p<0.001);students from single-parent families reported significantly higher depression levels than those from two-parent families(p<0.05);and graduate students exhibited significantly higher autonomy and well-being than undergraduates(p<0.05).Conclusions:These findings underscore not only the importance of filial piety beliefs for developing youth autonomy but also the critical role that mental health factors,such as depression and well-being,play in this process.The study concludes with a discussion of both theoretical implications and practical recommendations.These include strategies to foster reciprocal filial piety,strengthen parent-child relationships,and promote mental health.Additionally,the study outlines its limitations and proposes directions for future research.展开更多
This study investigated the relationship between college students’awe and depression,along with the mediating roles of future self-continuity and presence of meaning.891 Chinese college students(570 female;mean age 1...This study investigated the relationship between college students’awe and depression,along with the mediating roles of future self-continuity and presence of meaning.891 Chinese college students(570 female;mean age 18.59;SD 1.34)from one university completed four surveys:Dispositional Awe Subscale,Future self-continuity Scale,Meaning in Life Scale and Depression Scale.Using structural equation modelling and the bootstrap method,the results delineated that awe negatively related to depression,and future self-continuity and presence of meaning had a serial mediation effect,reducing depression.The study implies educational institutions should foster a positive mental health education environment,urging students to develop positive traits,enhancing well-being and resilience,and facilitating psychological development.展开更多
This longitudinal study examined the association between parental autonomy support and school-aged children’s adjustment across four major domains of school functioning,as well as the mediating role of children’s ex...This longitudinal study examined the association between parental autonomy support and school-aged children’s adjustment across four major domains of school functioning,as well as the mediating role of children’s executive function.Participants were 476 school-aged children(girl:49.2%,M_(age)=10.49 years,SD=1.32 years),who completed the Psychological Autonomy Support Scale,the Behavior Rating Inventory of Executive Function–2,and the Primary School Students’Psychological Suzhi Scale at baseline and at two subsequent follow-up assessments.Results from unconditional latent growth curve models and structural equation modeling indicated that paternal autonomy support was a significant predictor of children’s adjustment across all four school domains.In contrast,maternal autonomy support was significantly associated only with interpersonal adjustment.Both the intercept(initial level)and slope(rate of change)of children’s executive function significantly predicted their adjustment in all four domains.Notably,the initial level of executive function fully mediated the association between paternal autonomy support and school adjustment,whereas the rate of change in executive function did not serve as a significant mediator.Thesefindings underscore the importance of promoting parental autonomy-supportive behaviors-particularly among fathers-as a means to enhance children’s executive functioning and,consequently,their school adjustment.展开更多
BACKGROUND Dysphoria and despondency are prevalent psychological issues in patients undergoing Maintenance Hemodialysis(MHD)that significantly affect their quality of life(QOL).High levels of social support can signif...BACKGROUND Dysphoria and despondency are prevalent psychological issues in patients undergoing Maintenance Hemodialysis(MHD)that significantly affect their quality of life(QOL).High levels of social support can significantly improve the physical and mental well-being of patients undergoing MHD.Currently,there is limited research on how social support mediates the relationship between dysphoria,despondency,and overall QOL in patients undergoing MHD.It is imperative to investigate this mediating effect to mitigate dysphoria and despondency in patients undergoing MHD,ultimately enhancing their overall QOL.AIM To investigate the mediating role of social support in relationships between dysphoria,despondency,and QOL among patients undergoing MHD.METHODS Participants comprised 289 patients undergoing MHD,who were selected using a random sampling approach.The Social Support Rating Scale,Self-Rating Anxiety Scale,Self-Rating Depression Scale,and QOL Scale were administered.Correlation analysis was performed to examine the associations between social support,dysphoria,despondency,and QOL in patients undergoing MHD.To assess the mediating impact of social support on dysphoria,despondency,and QOL in patients undergoing MHD,a bootstrap method was applied.RESULTS Significant correlations among social support,dysphoria,despondency,and quality in patients undergoing MHD were observed(all P<0.01).Dysphoria and despondency negatively correlated with social support and QOL(P<0.01).Dysphoria and despondency had negative predictive impacts on the QOL of patients undergoing MHD(P<0.05).The direct effect of dysphoria on QOL was statistically significant(P<0.05).Social support mediated the relationship between dysphoria and QOL,and this mediating effect was significant(P<0.05).Similarly,the direct effect of despondency on QOL was significant(P<0.05).Moreover,social support played a mediating role between despondency and QOL,with a significant mediating effect(P<0.05).CONCLUSION These findings suggest that social support plays a significant mediating role in the relationship between dysphoria,despondency,and QOL in patients undergoing MHD.展开更多
BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health bec...BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health because of acute onset of disease,rapid progression,high recurrence rates,complex treatment methods,and treatment costs.AIM To explore the mediating effect of resilience on fear of disease progression and sleep quality in patients with hematological malignancies.METHODS A cross-sectional analysis of 100 patients with hematological malignancies,treated in the First Affiliated Hospital of Jinzhou Medical University between August 2022 and August 2023,was conducted.Patients were assessed using a general data survey,a simplified scale for the fear of progression(FoP)of disease,a resilience scale,and the Pittsburgh Sleep Quality Index.Statistical analysis was conducted to determine the relationship between various patient characteristics and FoP,resilience,and sleep quality.Spearman’s correlation analysis was used to examine the correlations between mental resilience,FoP,and sleep quality.RESULTS The total FoP score mean value in patients with hematological malignancies was 38.09±5.16;the total resilience score mean value was 40.73±7.04;and the Pittsburgh Sleep Quality Index score mean value was 10.72±1.90.FoP,resilience,and sleep quality of the patients were associated with family per capita monthly income and patient education level(P<0.05).Spearman correlation analysis revealed that FoP was negatively correlated with resilience and sleep quality scores(r=-0.560,-0.537,P<0.01),respectively,and resilience was significantly associated with sleep quality scores(r=0.688,P<0.01).Mediation analysis showed that the mediating effect of resilience between FoP and sleep quality in patients with hematological malignancies was-0.100 and accounted for 50.51%of the total effect.This indicated that FoP directly and indirectly affected sleep quality through the mesomeric effect of resilience.CONCLUSION Resilience is an intermediary variable between FoP and sleep quality in patients with hematological malignancies.Medical staff should evaluate and follow-up FoP and resilience to implement measures to improve sleep quality.展开更多
Background:In today’s society,parental stress has become a prevalent and significant issue,impacting not only parents’mental health but also potentially profoundly affecting children’s growth and education.This top...Background:In today’s society,parental stress has become a prevalent and significant issue,impacting not only parents’mental health but also potentially profoundly affecting children’s growth and education.This topic has garnered continuous attention from scholars.The present study aims to delve into the relationship between parental stress and children’s behavior,particularly focusing on children’s conformity and discipline development during crucial stages.This study aims to explore the relationship between parental stress,child conformity,and resilience,and further examines the mediating role of resilience in the relationship between parental stress and child conformity.Methods:We used three scales:the Parental Stress Scale,the Child Conformity Scale,and the Resilience Scale,to survey 890 elementary school students(aged 6–12)and their parents in the Beijing-Tianjin-Hebei region of China.We employed SPSS 26.0 software for data analysis,conducting descriptive statistics,correlation analysis,and mediation effect tests sequentially.In the mediation effect tests,we utilized structural equation modeling(SEM)and regression analysis to examine the mediation effects,ensuring the accuracy and scientific nature of our analysis.Results:Through descriptive statistics,correlation analysis,regression models,and mediation effect tests,we found that parental stress significantly negatively predicts child conformity,while resilience shows a significant positive prediction.Further mediation analysis indicates that resilience plays a partial mediating role between parental stress and child conformity,with the mediation effect accounting for 36.67%.Conclusion:These findings highlight the importance of the family environment on child behavior and provide valuable insights and recommendations for family education practices in the Beijing-Tianjin-Hebei region.Therefore,we suggest future research should further explore the complex relationships among parental stress,child conformity,and resilience,and examine regional differences to better promote children’s overall development.展开更多
Background:Adolescent anxiety has a significant impact on physical and mental health,and overparenting is recognized as one of the major factors affecting adolescent anxiety.The objective of this study was to investig...Background:Adolescent anxiety has a significant impact on physical and mental health,and overparenting is recognized as one of the major factors affecting adolescent anxiety.The objective of this study was to investigate the relationship between overparenting and adolescent anxiety,while also examining the mediating role of cognitive avoidance.Methods:Data were collected through a cross-sectional survey with 1931 valid responses using the Overparenting Scale,the Cognitive Avoidance Scale,and the Anxiety Self-Rating Scale.A structural equation modelling approach was used to test the mediating role of cognitive avoidance between overparenting and adolescent anxiety and to reveal the underlying mechanisms.The significance of the mediating effect was assessed based on maximum likelihood estimation.Differences in the mediating role of cognitive avoidance in the male and female samples were comparatively analyzed in the mediation effect analysis.Results:The study’s findings reveal a significant positive correlation between overparenting and adolescent anxiety(p<0.01),between overparenting and cognitive avoidance(p<0.01),and between cognitive avoidance and adolescent anxiety(p<0.01).Cognitive avoidance mediated the relationship between overparenting and adolescent anxiety.Overparenting can not only directly predict adolescent anxiety but also indirectly predict it through the mediating role of cognitive avoidance.Conclusion:This study validates the direct effect of overparenting on adolescent anxiety and reveals the mechanism of cognitive avoidance as a mediator.展开更多
Objective: To investigate the current situation and influencing factors of care giving burden among family caregivers with dementia and to analyze the Positive Aspect of caregivers between Social Capital and Caregiver...Objective: To investigate the current situation and influencing factors of care giving burden among family caregivers with dementia and to analyze the Positive Aspect of caregivers between Social Capital and Caregiver Burden. Methods: A total of 205 elderly dementia patients and family caregivers were select from 3 tertiary hospital by convenience sampling method in Zhengzhou. The general information questionnaire. The Social Capital Scale for Caregiver of People with Dementia, The Positive Aspect of Care giving scale and The Caregiver Burden Inventory were utilized for investigation. Results: In this study the scores of the Social Capital Scale of Caregivers with dementia were (48.76 ± 6.44), the scores of the Positive Aspect of Care giving scale were (37.41 ± 4.29), and the scores of the Caregiver Burden Inventory were (64.43 ± 10.89). The results of multiple linear regression analysis showed that patient’s age, patient’s disease duration, social capital, and positive feelings were the main influencing factors of caregiver’s burden of care (P Conclusion: The burden of family caregivers is at a medium-high level, and it is recommended that the medical, social levels fully mobilize the social support system of caregivers from the caregivers’ conditions, increase the level of the caregivers’ social capital, and pay attention to the positive feelings of the caregivers and regulate them in time social alleviate the burden of their care giving.展开更多
The shift towards online intelligent learning has become the norm in education and is now a fundamental part of modern educational activities.However,this new model can influence students’learning behavior and lead t...The shift towards online intelligent learning has become the norm in education and is now a fundamental part of modern educational activities.However,this new model can influence students’learning behavior and lead to changes in their approach to learning.Based on online intelligent learning,we investigated how the academic self-efficacy of nursing students affects their engagement with learning and explored the role of academic attribution as a mediator.Five hundred fifty-three nursing college students from Hebei and Hunan provinces in China participated in the online questionnaire.The results revealed that effort plays a mediating role in the relationship between academic self-efficacy and learning engagement.展开更多
Objective:To explore the association of sensory processing sensitivity(SPS)and stigma as well as the mediating role of fear of progression(FoP)in lung cancer patients.Methods:Two hundred and forty-two lung cancer pati...Objective:To explore the association of sensory processing sensitivity(SPS)and stigma as well as the mediating role of fear of progression(FoP)in lung cancer patients.Methods:Two hundred and forty-two lung cancer patients completed a self-reported questionnaire,which included the highly sensitive person scale(HSPS),fear of progression questionnaire-short form(FoP-Q-SF),and the Cataldo Lung Cancer Stigma Scale(CLCSS).Results:CLCSS was positively correlated with FoP(Pearson correlation=0.217,P<0.01)and HSPS(Pearson correlation=0.187,P<0.01),FoP was positively correlated with HSPS(Pearson correlation=0.199,P<0.01).FoP played a mediating role between SPS and stigma(a×b=0.025,95%confidence intervals[CI][0.004,0.054]),and the proportion of mediating effect(ab/c)was 21%(ab=0.025,c=0.120).Conclusions:Patients with higher SPS reported higher level of stigma,and FoP has a mediating role between SPS and stigma.Our discussion deemed that psychological intervention may help higher SPS patients reduce the harm of FoP and further reduce stigma.展开更多
Hexavalent chromium and its compounds are prevalent pollutants,especially in the work environment,pose a significant risk for multisystem toxicity and cancers.While it is known that chromium accumulation in the liver ...Hexavalent chromium and its compounds are prevalent pollutants,especially in the work environment,pose a significant risk for multisystem toxicity and cancers.While it is known that chromium accumulation in the liver can cause damage,the dose-response relationship between blood chromium(Cr)and liver injury,as well as the possible potential toxic mechanisms involved,remains poorly understood.To address this,we conducted a follow-up study of 590 visits from 305 participants to investigate the associations of blood Cr with biomarkers for liver injury,including serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBIL),and direct bilirubin(DBIL),and to evaluate the mediating effects of systemic inflammation.Platelet(PLT)and the platelet-to-lymphocyte ratio(PLR)were utilized as biomarkers of systemic inflammation.In the linear mixed-effects analyses,each 1-unit increase in blood Cr level was associated with estimated effect percentage increases of 0.82%(0.11%,1.53%)in TBIL,1.67%(0.06%,3.28%)in DBIL,0.73%(0.04%,1.43%)in ALT and 2.08%(0.29%,3.87%)in AST,respectively.Furthermore,PLT mediated 10.04%,11.35%,and 10.77%increases in TBIL,DBIL,and ALT levels induced by chromate,respectively.In addition,PLR mediated 8.26%and 15.58%of the association between blood Cr and TBIL or ALT.These findings shed light on the mechanisms underlying blood Cr-induced liver injury,which is partly due to worsening systemic inflammation.展开更多
AIM:To study the causal relationship between obesityrelated anthropometric traits and myopia and the mediating role of educational attainment(EA).METHODS:Univariable Mendelian randomization(UVMR)was performed to evalu...AIM:To study the causal relationship between obesityrelated anthropometric traits and myopia and the mediating role of educational attainment(EA).METHODS:Univariable Mendelian randomization(UVMR)was performed to evaluate the causal association between body mass index(BMI),height,waist-hip ratio(WHR,adjusted for BMI),and mean spherical equivalent(MSE).BMI was divided into fat and fat-free mass and included in multivariable Mendelian randomization(MVMR)to explore the roles of different BMI components in the causal relationship between BMI and MSE.A mediation analysis based on two-step Mendelian randomization(MR)was carried out.Specifically,UVMR was conducted to estimate the causal effect of BMI on EA.The direct effect of EA on MSE was estimated from MVMR.The mediation effect of EA in the BMI-EA-MSE model was calculated by the product of coefficients method.Expression quantitative trait loci(eQTL)-MR,reverse MR,and Linkage Disequilibrium Score Regression(LDSC)were performed to assess the robustness.RESULTS:Genetically predicted higher BMI had a positive total effect on MSE(βIVW=0.26 D,95%CI=0.14 to 0.37 D,P<0.001),whereas there was no significant association between height,WHR,and MSE.Fat mass was found to play a significant role in the effect of body mass on MSE(βIVW=0.50 D,95%CI=0.21 to 0.78 D,P=0.001),but there was no significant association between fat-free mass and MSE.The causal effect of BMI on EA was-0.14(95%CI=-0.16 to-0.11,P<0.001),and the direct effect of EA on MSE was-0.63 D(95%CI=-0.81 to-0.44 D,P<0.001).The mediating effect of EA in the BMI-EA-MSE model was 0.09 D(95%CI=0.06 to 0.12 D),with a mediation proportion of 33%(95%CI=22.1%to 44.6%).No reverse causal associations were detected except for BMI on EA.The results of eQTL-MR and LDSC were consistent with each MR analysis.CONCLUSION:Genetically predicted higher BMI decreases the degree of myopia with a 33%mediation proportion by EA,and fat mass provides a dominant protective role in body mass-myopia.As a supplement to previous observational studies,it provides strong evidence for the relationship between anthropometric traits and refractive errors and offers a theoretical basis for future measures to prevent and control myopia.展开更多
基金supported by the Teaching Quality and Teaching Reform Project of Dongguan City University(JY2022022301).
文摘This study examines how organizational support influences the career adaptability of novice university teachers in Guangdong,China,and the mediating role of teacher self-efficacy.Drawing on social cognitive theory and organizational support theory,we hypothesized that organizational support would positively predict career adaptability through self-efficacy.A cross-sectional survey was conducted with 326 novice teachers(with 1–3 years of teaching experience)from 12 universities in Guangdong.Data were analyzed using correlation analysis,hierarchical regression,and bootstrap.Results showed that:(1)organizational support was positively associated with both self-efficacy(r=0.62,P<0.001)and career adaptability(r=0.58,P<0.001);(2)self-efficacy fully mediated the relationship between organizational support and career adaptability(indirect effect=0.24,95%CI[0.18,0.31]),with a partial reduction in the direct effect fromβ=0.35 toβ=0.17(P<0.05);(3)female teachers reported higher self-efficacy than males(P<0.05),and teachers with 2 years of experience showed significantly higher adaptability than those with 1 year(P<0.05).The findings highlight the critical role of self-efficacy in translating organizational support into adaptability,providing empirical evidence for universities to design targeted support strategies.
基金supported by the Guangdong Basic and Applied Basic Research Foundation(2020A1515110608)Department of Education of Guangdong Province-Guangdong Province General University Youth Innovative Talent Project(2019KQNCX039).
文摘Background:Childhood environmental unpredictability(CEU)is crucial to personal development,profoundly influence physical and psychological growth particularly,and psychopathy is recognized as a dark personality trait.The aim of this study is to investigate the effects of insecure attachment and life history strategy(LHS)on the relationship between CEU and psychopathy by establishing a sequential mediation model based on evolutionary life history theory and cognitive-affective personality system.Methods:A group of 532 undergraduates completed the measurements for CEU,insecure attachment,LHS,and psychopathy,and Bootstrap mediation test through SPSS 25.0 and PROCESS macro tool was used to examine the relationship among these variables.Results:The results revealed positive relations between CEU and insecure attachment(β=0.87,p<0.001),CEU and LHS(β=0.11,p<0.001),and CEU and psychopathy(β=0.14,p<0.001).Insecure attachment was also positively associated with LHS(β=0.62,p<0.001)and psychopathy(β=0.04,p<0.001).In addition,LHS was significantly associated with psychopathy(β=0.08,p<0.001).The relationship between CEU and psychopathy is mediated independently and sequentially by insecure attachment and LHS.Conclusion:The current research shows the relationship between CEU and psychopathy,as well as the mechanism of insecure attachment and life history strategy as mediators.
文摘Objective:To analyze the mediating effect of psychological flexibility between death anxiety and quality of life in cancer patients.Methods:A convenience sampling method was used to select cancer patients who received treatment at our hospital from January 2022 to January 2024,by the inclusion and exclusion criteria.General information,psychological flexibility,death anxiety,and quality of life scores were collected for analysis.Result:The psychological flexibility and quality of life scores of cancer patients with an annual family income≤100,000 RMB were significantly lower than those of cancer patients with an annual family income>100,000 RMB(P<0.05),while the death anxiety scores were significantly lower for the former group as well(P<0.05).Cancer patients staged as Ⅰ-Ⅱ had significantly higher psychological flexibility and quality of life scores than those staged as Ⅲ-Ⅳ(P<0.05),while their death anxiety scores were significantly lower(P<0.05).Psychological flexibility in cancer patients was negatively correlated with death anxiety(r=-0.614,P<0.05)and positively correlated with quality of life(r=0.628,P<0.05),while death anxiety was negatively correlated with quality of life(r=-0.112,P<0.05).The direct effect of death anxiety on quality of life was-0.232,accounting for 58.32%of the total effect.The mediating effect of psychological flexibility between death anxiety and quality of life was-0.218,accounting for 41.83%of the total effect.Conclusion:Death anxiety can directly affect the quality of life of cancer patients,and it can also indirectly affect the quality of life through psychological flexibility.Clinicians should promptly address patients’death anxiety and provide interventions to enhance psychological flexibility,thereby improving the quality of life.
基金Henan Provincial Government-funded Excellent Clinical Medicine Talent Training Project(Project No.:ZF2024006)Hebei Province Medical Science Research Project Plan(Project No.:20240083)。
文摘Objective:Investigating the Mediating Role of Pain in the Relationship Between Sleep Quality and Health-Related Quality of Life Among Elderly Patients with Chronic Diseases.Methods:Using data from the 2018 China Health and Retirement Longitudinal Study(CHARLS),this study included 3,284 participants aged 60 years or older with chronic diseases.The sleep quality,pain status,health-related quality of life,and demographic-related data of these elderly patients were obtained.Pearson correlation analysis was conducted to assess the bivariate relationships among the variables.The mediating role of pain in the sleep quality-HRQoL relationship was tested using linear regression models,complemented by bootstrap sampling to verify the indirect effect.Results:Sleep quality was positively associated with health-related quality of life(r=0.218,p<0.001).Conversely,pain demonstrated significant negative correlations with both sleep quality(r=-0.496,p<0.001)and health-related quality of life(r=-0.067,p<0.001).The mediating effect results showed that pain played a partial mediating role between sleep quality and health-related quality of life in elderly patients with chronic diseases(effect value=0.049),and the mediating effect accounted for 23.33%.Conclusion:Pain is a mediating variable between sleep quality and health-related quality of life in elderly patients with chronic diseases.This suggests that clinical practice should incorporate pain assessment into standard clinical care of elderly patients with sleep disorders and chronic diseases.By alleviating pain,sleep quality can be improved,and subsequently,their health-related quality of life can be enhanced.
基金Supported by the Scientific Research Program of the Tianjin Education Commission(Natural Science),No.2023KJ033.
文摘BACKGROUND Several studies have suggested a close link between depression,overweight,and new-onset diabetes,particularly among middle-aged and older populations;however,the causal associations remain poorly understood.AIM To investigate the role of overweight in mediating the association between depression and new-onset diabetes in middle-aged and older populations.METHODS Data of 9426 individuals aged≥50 years from the 1998-2016 Health and Retirement Study database were analyzed.Weighted logistic regression was employed to obtain odds ratios(ORs)and 95%confidence intervals(95%CIs)for depression and new-onset diabetes in the middle-aged and older populations.Mediation analysis and the Sobel test were used to test the mediating effects of overweight between depression and the risk of new-onset diabetes.RESULTS New-onset diabetes was identified in 23.6%of the study population.Depression was significantly associated with new-onset diabetes(OR:1.18,95%CI:1.03-1.35,P value:0.014).Further adjustment for overweight attenuated the effect of depression on new-onset diabetes to 1.14(95%CI:1.00-1.30,P=0.053),with a significant mediating effect(P of Sobel test=0.003).The mediation analysis demonstrated that overweight accounted for 61%in depression for the risk of new-onset diabetes,with overweight having a partially mediating role in the depression-to-diabetes pathway.CONCLUSION New-onset diabetes was not necessarily a direct complication of depression;rather,depression led to behaviors that increase the risk of overweight and,consequently,new-onset diabetes.
基金supported by the Third Xinjiang Scientific Expedition Program(Grant No.2021xjkk0905)the National Natural Science Foundation of China(Grant No.42121001).
文摘New-type urbanization(NTU)is proposed by China to solve unsustainable issues and improve green development efficiency(GDE)during the process of rapid urbanization.However,the impact mechanism of NTU on GDE is unclear.Using panel data of 282 prefecture-level cities in China from 2010 to 2019,we measured NTU and GDE to describe their spatiotemporal pattern and relationship evolution.The fixed effects panel model and mediating effect panel model were further utilized to analyze the benchmark impact,mediating mechanism and spatiotem-poral heterogeneity of NTU on GDE.The results showed that NTU improved,with the highest levels observed in the eastern region,while GDE increased with fluctuations,performing better in both the eastern and western regions.With the proportion of double-high cities increasing from 13.83%to 43.62%,the NTU-GDE relationship was upgraded.Overall,every 1%improvement in NTU increased GDE by 0.3111%,and the enterprise effect,resident effect and government effect played a positive mediating role from high to low.During the later stage of NTU,its impact on GDE strengthened significantly,and the mediating role of governments was optimized.The eastern region was the only region with three positive mediating roles of governments,enterprises and residents.These findings will promote GDE through NTU in China and serve as a valuable reference for sustainable global urbanization.
文摘With the development of minimally invasive gynecological technology,hysteroscopic surgery has been widely used in the treatment of gynecological diseases due to its advantages of rapid recovery and minimal trauma.From the perspective of patients undergoing hysteroscopic surgery,this paper explores the influence of their psychological security on quality of life,analyzes the mediating effect of social support,and puts forward specific countermeasures and suggestions.The purpose is to improve the psychological security and quality of life of patients undergoing hysteroscopic surgery,and provide reference for the subsequent development of hysteroscopic surgery.
文摘BACKGROUND Depression is a leading global health concern with high suicide rates and recurrence.Cognitive models suggest that mental pain and automatic thoughts are central to depression's impact.The hypothesis is that self-compassion will be negatively associated with mental pain,mediated by automatic thoughts.AIM To determine the mediating role of automatic thoughts in the relationship between self-compassion and mental pain in individuals with depression.METHODS This cross-sectional study included 389 inpatients with depression from Tianjin Anding Hospital.Participants completed the Self-Compassion Scale-Chinese Version(SCS-C),Automatic Thought Questionnaire(ATQ),and Orbach&Mikulincer Mental Pain Scale-Chinese Version(OMMP).Data were analyzed using Pearson correlations,multiple linear regressions,and mediation analysis.RESULTS The SCS-C total score was 68.95±14.89,ATQ was 87.02±28.91,and OMMP was 129.01±36.74.Correlation analysis showed mental pain was positively associated with automatic thoughts(r=0.802,P<0.001)and negatively with selfcompassion(r=-0.636,P<0.001).Regression analysis indicated automatic thoughts(β=0.623,P<0.001)and self-compassion(β=-0.301,P<0.001)significantly predicted mental pain.Mediation analysis confirmed automatic thoughts partially mediated the relationship between self-compassion and mental pain(ab=-0.269,95%CI:-0.363 to-0.212).CONCLUSION Self-compassion is inversely related to mental pain in depression,with automatic thoughts playing a mediating role.These findings suggest potential therapeutic targets for alleviating mental pain in depressed patients.
文摘Background:Recent scholarly attention has increasingly focused on filial piety beliefs'impact on youth's psychological development.However,the mechanisms by which filial piety indirectly influences adolescent autonomy through depression and well-being remain underexplored.This study aimed to test a sequential mediation model among filial piety beliefs,depression,well-being,and autonomy in Taiwan region of China university students.Methods:A total of 566 Taiwan region of China undergraduate and graduate students,comprising 390 females and 176 males,and including 399 undergraduates and 167 graduate students,were recruited through convenience sampling.Data were collected via an online questionnaire.Validated instruments were employed,including the Filial Piety Scale(FPS),the Center for Epidemiological Studies Depression Scale(CES-D),the Chinese Well-being Inventory(CHI),and the Adolescent Autonomy Scale-Short Form(AAS-SF).Statistical analyses included group comparisons,correlation analyses,and structural equation modeling to examine the hypothesized relationships and mediation effects.Results:The results revealed that filial piety beliefs exerted a significant positive impact on adolescent autonomy,with depression and well-being serving as key mediators in this relationship.A sequential mediation effect was confirmed through structural equation modeling(β=0.052,95%CI[0.028,0.091]),with good model fit indices(x^(2)/df=4.25,RMSEA=0.076,CFI=0.968),supporting the hypothesized pathway from filial piety to autonomy via depression and well-being.In terms of demographic differences,male students showed significantly higher autonomy than females(p<0.001);students from single-parent families reported significantly higher depression levels than those from two-parent families(p<0.05);and graduate students exhibited significantly higher autonomy and well-being than undergraduates(p<0.05).Conclusions:These findings underscore not only the importance of filial piety beliefs for developing youth autonomy but also the critical role that mental health factors,such as depression and well-being,play in this process.The study concludes with a discussion of both theoretical implications and practical recommendations.These include strategies to foster reciprocal filial piety,strengthen parent-child relationships,and promote mental health.Additionally,the study outlines its limitations and proposes directions for future research.
基金supported by the Fundamental Research Funds for the Central Universities,and the Research Funds of Civil Aviation University of China,No.3122024012.
文摘This study investigated the relationship between college students’awe and depression,along with the mediating roles of future self-continuity and presence of meaning.891 Chinese college students(570 female;mean age 18.59;SD 1.34)from one university completed four surveys:Dispositional Awe Subscale,Future self-continuity Scale,Meaning in Life Scale and Depression Scale.Using structural equation modelling and the bootstrap method,the results delineated that awe negatively related to depression,and future self-continuity and presence of meaning had a serial mediation effect,reducing depression.The study implies educational institutions should foster a positive mental health education environment,urging students to develop positive traits,enhancing well-being and resilience,and facilitating psychological development.
基金supported by the National Natural Science Foundation of China(CN)(Grant No.32071074).
文摘This longitudinal study examined the association between parental autonomy support and school-aged children’s adjustment across four major domains of school functioning,as well as the mediating role of children’s executive function.Participants were 476 school-aged children(girl:49.2%,M_(age)=10.49 years,SD=1.32 years),who completed the Psychological Autonomy Support Scale,the Behavior Rating Inventory of Executive Function–2,and the Primary School Students’Psychological Suzhi Scale at baseline and at two subsequent follow-up assessments.Results from unconditional latent growth curve models and structural equation modeling indicated that paternal autonomy support was a significant predictor of children’s adjustment across all four school domains.In contrast,maternal autonomy support was significantly associated only with interpersonal adjustment.Both the intercept(initial level)and slope(rate of change)of children’s executive function significantly predicted their adjustment in all four domains.Notably,the initial level of executive function fully mediated the association between paternal autonomy support and school adjustment,whereas the rate of change in executive function did not serve as a significant mediator.Thesefindings underscore the importance of promoting parental autonomy-supportive behaviors-particularly among fathers-as a means to enhance children’s executive functioning and,consequently,their school adjustment.
基金Supported by the Natural Science Foundation Project of Xinjiang Uygur Autonomous Region,No.2021D01C143.
文摘BACKGROUND Dysphoria and despondency are prevalent psychological issues in patients undergoing Maintenance Hemodialysis(MHD)that significantly affect their quality of life(QOL).High levels of social support can significantly improve the physical and mental well-being of patients undergoing MHD.Currently,there is limited research on how social support mediates the relationship between dysphoria,despondency,and overall QOL in patients undergoing MHD.It is imperative to investigate this mediating effect to mitigate dysphoria and despondency in patients undergoing MHD,ultimately enhancing their overall QOL.AIM To investigate the mediating role of social support in relationships between dysphoria,despondency,and QOL among patients undergoing MHD.METHODS Participants comprised 289 patients undergoing MHD,who were selected using a random sampling approach.The Social Support Rating Scale,Self-Rating Anxiety Scale,Self-Rating Depression Scale,and QOL Scale were administered.Correlation analysis was performed to examine the associations between social support,dysphoria,despondency,and QOL in patients undergoing MHD.To assess the mediating impact of social support on dysphoria,despondency,and QOL in patients undergoing MHD,a bootstrap method was applied.RESULTS Significant correlations among social support,dysphoria,despondency,and quality in patients undergoing MHD were observed(all P<0.01).Dysphoria and despondency negatively correlated with social support and QOL(P<0.01).Dysphoria and despondency had negative predictive impacts on the QOL of patients undergoing MHD(P<0.05).The direct effect of dysphoria on QOL was statistically significant(P<0.05).Social support mediated the relationship between dysphoria and QOL,and this mediating effect was significant(P<0.05).Similarly,the direct effect of despondency on QOL was significant(P<0.05).Moreover,social support played a mediating role between despondency and QOL,with a significant mediating effect(P<0.05).CONCLUSION These findings suggest that social support plays a significant mediating role in the relationship between dysphoria,despondency,and QOL in patients undergoing MHD.
文摘BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health because of acute onset of disease,rapid progression,high recurrence rates,complex treatment methods,and treatment costs.AIM To explore the mediating effect of resilience on fear of disease progression and sleep quality in patients with hematological malignancies.METHODS A cross-sectional analysis of 100 patients with hematological malignancies,treated in the First Affiliated Hospital of Jinzhou Medical University between August 2022 and August 2023,was conducted.Patients were assessed using a general data survey,a simplified scale for the fear of progression(FoP)of disease,a resilience scale,and the Pittsburgh Sleep Quality Index.Statistical analysis was conducted to determine the relationship between various patient characteristics and FoP,resilience,and sleep quality.Spearman’s correlation analysis was used to examine the correlations between mental resilience,FoP,and sleep quality.RESULTS The total FoP score mean value in patients with hematological malignancies was 38.09±5.16;the total resilience score mean value was 40.73±7.04;and the Pittsburgh Sleep Quality Index score mean value was 10.72±1.90.FoP,resilience,and sleep quality of the patients were associated with family per capita monthly income and patient education level(P<0.05).Spearman correlation analysis revealed that FoP was negatively correlated with resilience and sleep quality scores(r=-0.560,-0.537,P<0.01),respectively,and resilience was significantly associated with sleep quality scores(r=0.688,P<0.01).Mediation analysis showed that the mediating effect of resilience between FoP and sleep quality in patients with hematological malignancies was-0.100 and accounted for 50.51%of the total effect.This indicated that FoP directly and indirectly affected sleep quality through the mesomeric effect of resilience.CONCLUSION Resilience is an intermediary variable between FoP and sleep quality in patients with hematological malignancies.Medical staff should evaluate and follow-up FoP and resilience to implement measures to improve sleep quality.
文摘Background:In today’s society,parental stress has become a prevalent and significant issue,impacting not only parents’mental health but also potentially profoundly affecting children’s growth and education.This topic has garnered continuous attention from scholars.The present study aims to delve into the relationship between parental stress and children’s behavior,particularly focusing on children’s conformity and discipline development during crucial stages.This study aims to explore the relationship between parental stress,child conformity,and resilience,and further examines the mediating role of resilience in the relationship between parental stress and child conformity.Methods:We used three scales:the Parental Stress Scale,the Child Conformity Scale,and the Resilience Scale,to survey 890 elementary school students(aged 6–12)and their parents in the Beijing-Tianjin-Hebei region of China.We employed SPSS 26.0 software for data analysis,conducting descriptive statistics,correlation analysis,and mediation effect tests sequentially.In the mediation effect tests,we utilized structural equation modeling(SEM)and regression analysis to examine the mediation effects,ensuring the accuracy and scientific nature of our analysis.Results:Through descriptive statistics,correlation analysis,regression models,and mediation effect tests,we found that parental stress significantly negatively predicts child conformity,while resilience shows a significant positive prediction.Further mediation analysis indicates that resilience plays a partial mediating role between parental stress and child conformity,with the mediation effect accounting for 36.67%.Conclusion:These findings highlight the importance of the family environment on child behavior and provide valuable insights and recommendations for family education practices in the Beijing-Tianjin-Hebei region.Therefore,we suggest future research should further explore the complex relationships among parental stress,child conformity,and resilience,and examine regional differences to better promote children’s overall development.
基金supported by funding of Educational Development Research Center of Southern Xinjiang.
文摘Background:Adolescent anxiety has a significant impact on physical and mental health,and overparenting is recognized as one of the major factors affecting adolescent anxiety.The objective of this study was to investigate the relationship between overparenting and adolescent anxiety,while also examining the mediating role of cognitive avoidance.Methods:Data were collected through a cross-sectional survey with 1931 valid responses using the Overparenting Scale,the Cognitive Avoidance Scale,and the Anxiety Self-Rating Scale.A structural equation modelling approach was used to test the mediating role of cognitive avoidance between overparenting and adolescent anxiety and to reveal the underlying mechanisms.The significance of the mediating effect was assessed based on maximum likelihood estimation.Differences in the mediating role of cognitive avoidance in the male and female samples were comparatively analyzed in the mediation effect analysis.Results:The study’s findings reveal a significant positive correlation between overparenting and adolescent anxiety(p<0.01),between overparenting and cognitive avoidance(p<0.01),and between cognitive avoidance and adolescent anxiety(p<0.01).Cognitive avoidance mediated the relationship between overparenting and adolescent anxiety.Overparenting can not only directly predict adolescent anxiety but also indirectly predict it through the mediating role of cognitive avoidance.Conclusion:This study validates the direct effect of overparenting on adolescent anxiety and reveals the mechanism of cognitive avoidance as a mediator.
文摘Objective: To investigate the current situation and influencing factors of care giving burden among family caregivers with dementia and to analyze the Positive Aspect of caregivers between Social Capital and Caregiver Burden. Methods: A total of 205 elderly dementia patients and family caregivers were select from 3 tertiary hospital by convenience sampling method in Zhengzhou. The general information questionnaire. The Social Capital Scale for Caregiver of People with Dementia, The Positive Aspect of Care giving scale and The Caregiver Burden Inventory were utilized for investigation. Results: In this study the scores of the Social Capital Scale of Caregivers with dementia were (48.76 ± 6.44), the scores of the Positive Aspect of Care giving scale were (37.41 ± 4.29), and the scores of the Caregiver Burden Inventory were (64.43 ± 10.89). The results of multiple linear regression analysis showed that patient’s age, patient’s disease duration, social capital, and positive feelings were the main influencing factors of caregiver’s burden of care (P Conclusion: The burden of family caregivers is at a medium-high level, and it is recommended that the medical, social levels fully mobilize the social support system of caregivers from the caregivers’ conditions, increase the level of the caregivers’ social capital, and pay attention to the positive feelings of the caregivers and regulate them in time social alleviate the burden of their care giving.
基金Research Project on Education and Teaching Reform at Hebei University of Chinese Medicine(22yb-45)Hebei Province Higher Education Teaching Reform Research and Practice Project(2021GJJG278)。
文摘The shift towards online intelligent learning has become the norm in education and is now a fundamental part of modern educational activities.However,this new model can influence students’learning behavior and lead to changes in their approach to learning.Based on online intelligent learning,we investigated how the academic self-efficacy of nursing students affects their engagement with learning and explored the role of academic attribution as a mediator.Five hundred fifty-three nursing college students from Hebei and Hunan provinces in China participated in the online questionnaire.The results revealed that effort plays a mediating role in the relationship between academic self-efficacy and learning engagement.
基金supported by the Scientific Research Fund project of Education Department of Yunnan Province(No.2022J0177)Yunnan Province Science and Technology Plan Project(No.202101AY070001-178)Topic of Nursing Psychology Professional Committee of Chinese Mental Health Association(No.22-23-121)。
文摘Objective:To explore the association of sensory processing sensitivity(SPS)and stigma as well as the mediating role of fear of progression(FoP)in lung cancer patients.Methods:Two hundred and forty-two lung cancer patients completed a self-reported questionnaire,which included the highly sensitive person scale(HSPS),fear of progression questionnaire-short form(FoP-Q-SF),and the Cataldo Lung Cancer Stigma Scale(CLCSS).Results:CLCSS was positively correlated with FoP(Pearson correlation=0.217,P<0.01)and HSPS(Pearson correlation=0.187,P<0.01),FoP was positively correlated with HSPS(Pearson correlation=0.199,P<0.01).FoP played a mediating role between SPS and stigma(a×b=0.025,95%confidence intervals[CI][0.004,0.054]),and the proportion of mediating effect(ab/c)was 21%(ab=0.025,c=0.120).Conclusions:Patients with higher SPS reported higher level of stigma,and FoP has a mediating role between SPS and stigma.Our discussion deemed that psychological intervention may help higher SPS patients reduce the harm of FoP and further reduce stigma.
基金supported by the National Natural Science Foundation of China(Nos.82273603,82003427,U2004202)。
文摘Hexavalent chromium and its compounds are prevalent pollutants,especially in the work environment,pose a significant risk for multisystem toxicity and cancers.While it is known that chromium accumulation in the liver can cause damage,the dose-response relationship between blood chromium(Cr)and liver injury,as well as the possible potential toxic mechanisms involved,remains poorly understood.To address this,we conducted a follow-up study of 590 visits from 305 participants to investigate the associations of blood Cr with biomarkers for liver injury,including serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBIL),and direct bilirubin(DBIL),and to evaluate the mediating effects of systemic inflammation.Platelet(PLT)and the platelet-to-lymphocyte ratio(PLR)were utilized as biomarkers of systemic inflammation.In the linear mixed-effects analyses,each 1-unit increase in blood Cr level was associated with estimated effect percentage increases of 0.82%(0.11%,1.53%)in TBIL,1.67%(0.06%,3.28%)in DBIL,0.73%(0.04%,1.43%)in ALT and 2.08%(0.29%,3.87%)in AST,respectively.Furthermore,PLT mediated 10.04%,11.35%,and 10.77%increases in TBIL,DBIL,and ALT levels induced by chromate,respectively.In addition,PLR mediated 8.26%and 15.58%of the association between blood Cr and TBIL or ALT.These findings shed light on the mechanisms underlying blood Cr-induced liver injury,which is partly due to worsening systemic inflammation.
基金Supported by Hubei Province Key Research and Development Program Project,Hubei Provincial Department of Science and Technology(No.2022BCA044)Key Scientific Research Projects of Health Commission of Hubei Province in 2023-2024,Health Commission of Hubei Province(No.WJ2023Z006).
文摘AIM:To study the causal relationship between obesityrelated anthropometric traits and myopia and the mediating role of educational attainment(EA).METHODS:Univariable Mendelian randomization(UVMR)was performed to evaluate the causal association between body mass index(BMI),height,waist-hip ratio(WHR,adjusted for BMI),and mean spherical equivalent(MSE).BMI was divided into fat and fat-free mass and included in multivariable Mendelian randomization(MVMR)to explore the roles of different BMI components in the causal relationship between BMI and MSE.A mediation analysis based on two-step Mendelian randomization(MR)was carried out.Specifically,UVMR was conducted to estimate the causal effect of BMI on EA.The direct effect of EA on MSE was estimated from MVMR.The mediation effect of EA in the BMI-EA-MSE model was calculated by the product of coefficients method.Expression quantitative trait loci(eQTL)-MR,reverse MR,and Linkage Disequilibrium Score Regression(LDSC)were performed to assess the robustness.RESULTS:Genetically predicted higher BMI had a positive total effect on MSE(βIVW=0.26 D,95%CI=0.14 to 0.37 D,P<0.001),whereas there was no significant association between height,WHR,and MSE.Fat mass was found to play a significant role in the effect of body mass on MSE(βIVW=0.50 D,95%CI=0.21 to 0.78 D,P=0.001),but there was no significant association between fat-free mass and MSE.The causal effect of BMI on EA was-0.14(95%CI=-0.16 to-0.11,P<0.001),and the direct effect of EA on MSE was-0.63 D(95%CI=-0.81 to-0.44 D,P<0.001).The mediating effect of EA in the BMI-EA-MSE model was 0.09 D(95%CI=0.06 to 0.12 D),with a mediation proportion of 33%(95%CI=22.1%to 44.6%).No reverse causal associations were detected except for BMI on EA.The results of eQTL-MR and LDSC were consistent with each MR analysis.CONCLUSION:Genetically predicted higher BMI decreases the degree of myopia with a 33%mediation proportion by EA,and fat mass provides a dominant protective role in body mass-myopia.As a supplement to previous observational studies,it provides strong evidence for the relationship between anthropometric traits and refractive errors and offers a theoretical basis for future measures to prevent and control myopia.
